{
    "rJZe1IHB": {
        "id": "rJZe1IHB",
        "title": "Enhanced Terrestrial Carbon Uptake in the Northern High Latitudes in the 21st Century from the C4MIP Model Projections",
        "abstract": "",
        "keywords": [
            "carbon-climate",
            "terrestrial carbon",
            "northern high latitudes",
            "climate change",
            "soil carbon",
            "organic matter",
            "carbon cycle",
            "cumulant",
            "vegetative growth",
            "global change",
            "climate model",
            "boreal forest",
            "carbon storage",
            "carbon sink"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Renu Joseph",
                "org": ""
            },
            {
                "name": "Ning Zeng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "LNZGIKx7": {
        "id": "LNZGIKx7",
        "title": "Interactions between biogenic selenium nanoparticles and goethite colloids and consequence for remediation of elemental mercury contaminated groundwater.",
        "abstract": "Ubiquitous colloidal minerals such as goethite can have a significant impact on the performance of nanoparticles-based groundwater remediation due to aggregation. Heteroaggregation and retention of Se nanoparticles (SeNPs) by goethite in groundwater, and its impact on Hg remediation by SeNPs were investigated in this study. In order to mitigate the adverse effects of aggregation, the effects of bacterial extracellular polymeric substances (EPS) on the stability of SeNPs and Hg sequestration using SeNPs were also evaluated. Heteroaggregation of SeNPs with goethite in groundwater was stronger than homoaggregation of SeNPs or goethite. Addition of EPS could slightly decrease homoaggregation of SeNPs and significantly reduce heteroaggregation. Column transport experiments showed that goethite coated quartz sand could retain 1.36 times a higher amount of SeNPs than uncoated quartz sand. Hg remediation by SeNPs was significantly inhibited by heteroaggregation of SeNPs with goethite and EPS could effectively mitigate this inhibitory effect. The Hg removal efficiency decreased to 71.6% and 66.9%, respectively in the presence of 20 and 100mgL goethite. When 200mgL EPS was added together with 100mgL goethite, 81.2% of the supplied Hg was removed from the groundwater. This study demonstrates that the widespread presence of goethite could significantly reduce the remediation efficiency of Hg contaminated groundwater and that EPS is a promising amendment for mitigating the adverse effects of heteroaggregation. This research also contributes to a further understanding of the environmental behaviour of nanoparticles.",
        "keywords": [
            "Attachment efficiency",
            "Extracellular polymeric substances",
            "Heteroaggregation",
            "Homoaggregation",
            "Remediation"
        ],
        "authors": [
            {
                "name": "Xiaonan Wang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Geomicrobiology Group, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK; University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Daoyong Zhang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Yan Liang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province, College of Environment, Zhejiang University of Technology, Hangzhou 310014, China. Electronic address: panxl@zjut.edu.cn."
            },
            {
                "name": "Geoffrey Michael Gadd",
                "org": "Geomicrobiology Group, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "vI8C99RT": {
        "id": "vI8C99RT",
        "title": "Multiwall carbon nanotubes modulate paraquat toxicity in Arabidopsis thaliana.",
        "abstract": "Carbon nanotubes can be either toxic or beneficial to plant growth and can also modulate toxicity of organic contaminants through surface sorption. The complex interacting toxic effects of carbon nanotubes and organic contaminants in plants have received little attention in the literature to date. In this study, the toxicity of multiwall carbon nanotubes (MWCNT, 50 mg/L) and paraquat (MV, 0.82 mg/L), separately or in combination, were evaluated at the physiological and the proteomic level in Arabidopsis thaliana for 7-14 days. The results revealed that the exposure to MWCNT had no inhibitory effect on the growth of shoots and leaves. Rather, MWCNT stimulated the relative electron transport rate and the effective photochemical quantum yield of PSII value as compared to the control by around 12% and lateral root production up to nearly 4-fold as compared to the control. The protective effect of MWCNT on MV toxicity on the root surface area could be quantitatively explained by the extent of MV adsorption on MWCNT and was related to stimulation of photosynthesis, antioxidant protection and number and area of lateral roots which in turn helped nutrient assimilation. The influence of MWCNT and MV on photosynthesis and oxidative stress at the physiological level was consistent with the proteomics analysis, with various over-expressed photosynthesis-related proteins (by more than 2 folds) and various under-expressed oxidative stress related proteins (by about 2-3 folds). This study brings new insights into the interactive effects of two xenobiotics (MWCNT and MV) on the physiology of a model plant.",
        "keywords": [
            "Arabidopsis thaliana",
            "Multiwall carbon nanotubes",
            "Oxidative stress",
            "Paraquat",
            "Photosynthesis",
            "Proteomics"
        ],
        "authors": [
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Jiahui Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300 RA, Leiden, The Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, The Netherlands."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tingheng Zhu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2017
    },
    "t3gN6z5u": {
        "id": "t3gN6z5u",
        "title": "Understanding the influence of glyphosate on the structure and function of freshwater microbial community in a microcosm.",
        "abstract": "Glyphosate, one of the most popular herbicides, has become a prominent aquatic contaminant because of its huge usage. The eco-safety of glyphosate is still in controversy, and it is inconclusive how glyphosate influences aquatic microbial communities. In the present study, the effects of glyphosate on the structure and function of microbial communities in a freshwater microcosm were investigated. 16S/18S rRNA gene sequencing results showed that glyphosate treatment (2.5 mg L, 15 days) did not significantly alter the physical and chemical condition of the microcosm or the composition of the main species in the community, but metatranscriptomic analyses indicated that the transcriptions of some cyanobacteria were significantly influenced by glyphosate. The microbial community enhanced the gene expression in pathways related to translation, secondary metabolites biosynthesis, transport and catabolism to potentially withstand glyphosate contamination. In the low phosphorus (P) environment, a common cyanobacterium, Synechococcus, plays a special role by utilizing glyphosate as P source and thus reducing its toxicity to other microbes, such as Pseudanabaena. In general, addition of glyphosate in our artificial microcosms did not strongly affect the aquatic microbial community composition but did alter the community's transcription levels, which might be potentially explained by that some microbes could alleviate glyphosate's toxicity by utilizing glyphosate as a P source.",
        "keywords": [
            "Cyanobacteria",
            "Ecotoxicity",
            "Metatranscriptome",
            "Pesticides",
            "Phosphorus source"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Nuohan Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Andries Debognies",
                "org": "Faculty of Bioscience Engineering, Ghent University Campus Kortrijk, Graaf Karel de Goedelaan 5, 8500, Kortrijk, Belgium."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2020
    },
    "2ZZGVOEP": {
        "id": "2ZZGVOEP",
        "title": "Assessment of the Bacterial Community for Denitrifying Removal of Nitric Oxide in a Rotating Drum Biofilter by Denaturing Gradient Gel Electrophoresis",
        "abstract": "",
        "keywords": [
            "16s ribosome dna (16s rrna)",
            "denaturing gradient gel electrophoresis (dgge)",
            "microbial diversity",
            "rotating drum biofilter",
            "sequence",
            "denitrification",
            "efficiency",
            "denitrifying bacteria",
            "phylogenetics",
            "biofilms",
            "biological treatment",
            "waste treatment",
            "ribosomal rna",
            "nitric oxide",
            "denaturing gradient gel electrophoresis"
        ],
        "authors": [
            {
                "name": "Jun Chen",
                "org": ""
            },
            {
                "name": "Zhi-Ye Wang",
                "org": ""
            },
            {
                "name": "Yi-Feng Jiang",
                "org": ""
            },
            {
                "name": "Hai-Feng Qian",
                "org": ""
            },
            {
                "name": "Wei Zhang",
                "org": ""
            },
            {
                "name": "Jian-Meng Chen",
                "org": ""
            }
        ],
        "venue": "Environmental Engineering Science",
        "year": 2009
    },
    "YXCUhKzb": {
        "id": "YXCUhKzb",
        "title": "The effect of glufosinate on nitrogen assimilation at the physiological, biochemical and molecular levels in Phaeodactylum tricornutum.",
        "abstract": "This study investigated the effects of glufosinate, a widely used herbicide, on the marine diatom Phaeodactylum tricornutum through short-term toxicity tests at the physiological and gene transcriptional levels. Glufosinate (4 mg L(-1)) decreased the amount of pigments but increased reactive oxygen species (ROS) and malondialdehyde levels. As a glutamine synthetase (GS) inhibitor, glufosinate affected the transcripts and activities of key enzymes related to nitrogen assimilation. Transcript levels of GS and nitrate reductase (NR) in P. tricornutum decreased to only 57 and 26 % of the control. However, transcript levels of nitrate transporter (NRT) and the small subunit of glutamate synthase (GltD) were 1.79 and 1.76 times higher than that of the control. The activities of NRT, GS and GOGAT were consistent with gene expression except for NR, which was regulated mainly by post-translational modification. Furthermore, the results of electron microscopy showed that chloroplast structure was disrupted in response to glufosinate exposure. These results demonstrated that glufosinate first disturbed nitrogen metabolism and caused a ROS burst, which disrupted chloroplast ultrastructure. Ultimately, the growth of P. tricornutum was greatly inhibited by glufosinate.",
        "keywords": [],
        "authors": [
            {
                "name": "Jun Xie",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xiaocui Bai",
                "org": ""
            },
            {
                "name": "Yali Li",
                "org": ""
            },
            {
                "name": "Chongchong Sun",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Ecotoxicology (London, England)",
        "year": 2014
    },
    "wwQnWCm7": {
        "id": "wwQnWCm7",
        "title": "Enzymatic preparation and functional properties of wheat gluten hydrolysates",
        "abstract": "The water-insolublity of wheat gluten is one of the major limitations for its more extensive use in food processing. Wheat gluten was enzymatically hydrolyzed by several commercially available proteases (Pancreatin Trypsin 6.0S, Porcine pepsin, Pancreatin and Alcalase 2.4L) with protein recovery varying from 42.5 ± 0.7% to 81.3 ± 0.1%. The hydrolytic efficiency of these proteases on wheat gluten was also compared. Alcalase served best for the preparation of wheat gluten hydrolysates (WGHs). Thus, Alcalase-assisted hydrolysates of wheat gluten (AWGHs) with different degrees of hydrolysis (DH 5.0, 10.0 and 15.0%) were further assessed for their functionalities. All the AWGHs had excellent solubility (>60%) over a pH range of 2–12. The emulsifying and foaming properties of AWGH with relatively low DH (5.0%) were remarkably higher compared to the original gluten. However, extensive hydrolysis of gluten resulted in remarkable reduction in emulsifying and foaming properties. Keywords Wheat gluten Enzymatic hydrolysis Alcalase Functional property 1 Introduction Proteases can be used to prepare peptides with characteristics that are a function of hydrolyzed protein, enzyme used, and conditions of hydrolysis. The products are distinguished from the original protein mainly by their small molecular size. Moreover, cleavage is usually accompanied by important structural rearrangements that tend to expose to the aqueous phase some hydrophobic regions originally buried within the protein molecule ( Phillips & Beuchat, 1981 ). Peptides can therefore be very different from the parent proteins and may possess new nutritional, functional or biological properties. Enzymatic hydrolysates are thus used in food industry, parachemistry and pharmacy. Wheat gluten represents about 72% of wheat protein. It is essentially used to improve the properties of flour for bread-making and as an additive in the baking industry; however its uses are becoming more diversified, both inside and outside the food industries, with the expansion of wheat starch production ( Bietz & Lookhart, 1996; Lens, Mulder, & Kolster, 1999; Maningart, Demeritt, Chinnaswamy, & Bassi, 1999 ). Some studies have shown the possibility of using limited enzymatic proteolysis as a processing technology. Study of protease action on wheat gluten proteins has had three major objectives. The first was to relate the physicochemical properties of gluten proteins with their functional properties. In particular, a number of authors have tried to modify the solubility of the gluten fraction enzymatically ( Batey, 1985; Mimouni, Azanza, & Raymond, 1999 ). This property is primordial, since it governs the use of these protein components as stabilizers for foams or emulsions ( Linarès, Larré, Lemeste, & Popineau, 2000; Popineau, Huchet, Larré, & Bérot, 2002 ). The second objective was to search for peptides with biological activity, especially with respect to celiac disease (gluten intolerance) ( Huebner, Lieberman, Rubino, & Wall, 1984; Cornell & Mothes, 1995; Cornell, 1998; Suetsuna & Chen, 2002 ). The third objective was to obtain structural or genetic information by comparing the composition of peptide fractions from different proteins ( Bietz & Rothfus, 1970; Danno & Natake, 1980; Galili & Feldman, 1985; Masson, Tomé, & Popineau, 1986; Shewry et al., 1984b ). Because of the insoluble nature of wheat gluten and the complexity of their composition, enzymatic hydrolysis of wheat gluten must usually be studied in heterogeneous dispersed or paste systems, and the products of hydrolysis are difficult to isolate and to characterize. Different proteases have been tried, such as pepsin, trypsin, papain, bromelain, and subtilisin. Wheat gluten hydrolysis results in peptide mixtures with high solubilities and altered foaming and emulsifying characteristics, depending on the degree of hydrolysis. The present study was designed to examine the use of commercially available proteolytic enzymes for the preparation of wheat gluten hydrolysates (WGHs), to select a suitable protease for the preparation of WGHs with different degrees of hydrolysis and to investigate selected functionalities of the resultant products. 2 Materials and methods 2.1 Materials Wheat gluten was kindly supplied by Lotus Gourmet Powder Group Company (Henan, China). 2.2 Chemicals and reagents All chemicals and reagents used in this work were food-grade or reagent-grade. Alcalase 2.4L (EC 3.4.21.62, from B. licheniformis, 2.4 AU/g) and Pancreatin Trypsin Novo 6.0S (PTN 6.0S) (EC 3.4.21.4, from porcine pancreas, 1350 usp-u/mg)were donated by Novo Nordisk (Bagsvaerd, Denmark). Porcine pepsin (EC 3.4.23.1, 3140 BP u/g) and Pancreatin (146 USP u/mg) were supplied by Deyang biochemical products company (Sichuan, China). 2.3 Proteolysis with different enzymes 2.3.1 Hydrolysis with pepsin Wheat gluten was dissolved as a 5% (w/v) solution in 100 mM HCl to make the final pH 2.0. Pepsin (0.1% in water) was added and the mixture was incubated at 37 °C for 24 h. No significant change of the pH was found during the reaction. 2.3.2 Proteolysis with Alcalase, trypsin and pancreatin Wheat gluten was dissolved as a 5% (w/v) solution in 100 mM phosphate buffer (pH 8.5). The suspension was incubated for 30 min at optimum temperature (see Table 1 ), depending on the enzyme used, and continuously stirred. The reaction was initiated by the addition of the enzyme to give a final enzyme-to-substrate ratio of 1:100 (w/w). The reaction was continued for 6 h and the pH of the mixture was kept constant by continuously adding a 4 M NaOH solution to the reaction mixture. 2.3.3 Termination of the enzymatic reaction After the reaction period, the mixture was cooled, adjusted the pH to 7.0 with 0.5 M and 4 M NaOH and heating at 95 °C for 10 min to inactivate the enzyme. Then the mixture was centrifuged at 10,000 g for 20 min at 4 °C in a ZOPR-52D refrigerating centrifuge (Hitachi Koki Co. Ltd., Tokyo, Japan). The supernatant was freeze-dried and stored at −20 °C. 2.3.4 Preparation of Alcalase-assisted wheat gluten hydrolysates (AWGHs) with different degrees of hydrolysis When the Alcalase hydrolysis had reached the set degree of hydrolysis (5%, 10% or 15%), it was terminated by adjusting the pH and heating at 95 °C for 10 min. Then the reaction mixture was centrifuged and the supernatant was freeze-dried. Samples were kept at −20 °C until needed for functional tests. 2.4 Degree of hydrolysis 2.4.1 pH-stat assay The degree of hydrolysis (DH%), defined as the percent ratio of the number of peptide bonds broken ( h ) to the total number of bonds per unit weight ( h tot ), in each case, was calculated from the amount of base consumed ( Adler-Nissen, 1986 ), as given below: DH % = h × 100 h tot = B × N b × 100 α × M p × h tot where B is base consumption in ml; N b is normality of the base; α is average degree of dissociation of the α-NH 2 groups; MP is mass of protein (N × 5.7) in g; h is the hydrolysis equivalents in meqv/g protein and h tot is total number of peptide bonds in the protein substrate (8.38 meqv/g gluten protein). 2.4.2 Trichloroacetic acid (TCA) assay For peptic hydrolysis, DH was determined by the ratio of the percentage of 10% TCA-soluble nitrogen to total nitrogen in the sample ( Drago & González, 2001 ). Aliquots were removed at the final time required and mixed with 20% TCA to create 10% TCA-soluble and TCA-insoluble fractions. After 30 min, the mixture was centrifuged at 3000 g and the supernatants were analysed for nitrogen by the semimicro-Kjeldahl method ( AOAC, 1990 ). The degree of hydrolysis was calculated as follows: DH % = 10% TCA-soluble N in hydrolysate - 10 % TCA-soluble N in sample without hydrolysis total N of dispersion × 100 2.5 Determination of protein recovery of WGHs from wheat gluten Protein recovery was calculated as the amount of protein (%N × 5.7) present in the hydrolysates relative to the initial amount of protein present in the reaction mixture. This is an important measurement because a maximum recovery is desired in the production of hydrolyzed food proteins. 2.6 Functional properties of AWGHs 2.6.1 Solubility The modified nitrogen solubility index (NSI) procedure of Morr et al. (1985) was used to measure the solubility of gluten and AWGH samples at a pH range of 2–12. The solubility of the hydrolysate was expressed as the fraction of soluble N to total N. 2.6.2 Emulsifying capacity and stability The emulsifying activity of gluten and AWGHs was determined by the turbidimetric method of Pearce and Kinsella (1978) , with minor modifications. To prepare the emulsions, 9 ml of soybean oil and 21 ml of 0.2% protein solution (pH 7.0) were shaken together and homogenized in blender at 12,000 g for 1 min at 20 °C. Emulsion (50 μl) was taken from the bottom of the container after different time intervals (0 and 30 min) and diluted with 5 ml of 0.1% SDS solution. The absorbance of diluted emulsions was then determined at 500 nm and indicated as a turbidity. Emulsifying activity was determined from the absorbance measured immediately after emulsion formation. The emulsion stability was expressed as the difference value of the absorbance between 0 and 30 min. 2.6.3 Foaming capacity and stability Foaming capacity was evaluated by the method of Bernardi Don, Pilosof, and Bartholomai (1991) , with minor modifications. A 50 ml quantity of 1.0% protein solution was mixed thoroughly using an homogenizer at 10,000 g for 1 min in a 250 ml graduated cylinder. Foaming capacity (FC) was calculated as the percent increase in volume of the protein dispersion upon mixing. Foaming stability (FS) was estimated as the percent of foam remaining after 60 min. 3 Results and discussion 3.1 Enzymatic hydrolysis of wheat gluten The control of enzymatic hydrolysis was related to the mechanism of proteolytic reactions involving a soluble enzyme and an insoluble substrate (wheat gluten). The hydrolysis of wheat gluten with Alcalase, Trypsin and Pancreatin proceeded at a rapid rate during the initial 30 min and then slowed down thereafter ( Fig. 1 ). This was typical for hydrolysis curves published for fish protein and whey protein ( Kristinsson & Rasco, 2000a; Mutilangi, Panyam, & Kilara, 1995 ). DH values varied from 0% to 15.8% after 360 min of incubation, depending upon the enzymes used. Alcalase gave the highest DH values and was more efficient for gluten hydrolysis than the others. For peptic hydrolysis of wheat gluten, DH was determined by the TCA assay. The hydrolytic curve ( Fig. 2 ) was similar to Fig. 1 , with DH values varied from 0% to 27.2% during 24 h of incubation. The correlation between the results of the two determination methods of degree of hydrolysis in wheat gluten hydrolysis with Alcalase is shown in Fig. 3 . The results obtained by the TCA assay were highly correlated with those obtained by the pH-stat assay (correlation coefficient of 0.9843), suggesting that the peptides formed during the initial stages of hydrolysis served as the substrate for the formation of smaller peptides, soluble in TCA. This was in agreement with the results reported by Netto and Galeazzi (1998) , who evaluated the hydrolysis of soy protein isolates by the two assays and obtained a good correlation between them. For the gluten hydrolysis with Alcalase, the DH varied from 0% to 16.0% and 0% to 63.7% determined, respectively, by pH-stat and TCA assays. This indicated that the hydrolytic efficiency of Alcalase was much higher than that of pepsin. 3.2 Protein recovery of WGHs from wheat gluten The yields of protein hydrolysates with different proteolytic enzymes are given in Table 2 . Although many factors affected the hydrolysis yield, the type of enzyme used had the greatest effect on the yield and properties of the final product. High protein recovery by Alcalase and its low cost may provide an incentive for using it in commercial operations. Thus, functional properties of protein hydrolysates so prepared (AWGHs) were further evaluated in order to determine their suitability in different industrial and/or food applications. 3.3 Functionalities of wheat gluten hydrolysates with Alcalase (AWGHs) 3.3.1 Solubility An increase in the extent of enzymatic hydrolysis corresponded to a considerable increase in the nitrogen solubility over the pH range studied, thus indicating a positive relationship ( Fig. 4 ). It has been suggested that an increase in the solubility of protein hydrolysates over that of the original protein is due to the reduction of its secondary structure and also to the enzymatic release of smaller polypeptide units from the protein ( Adler-Nissen, 1986; Chobert, Bertrand-Harb, & Nicolas, 1988 ). All AWGHs presented a similar pattern of NSI values, which could be due to the fact that the specificity of the enzyme used was the same in all these cases. With the increase of DH, the NSI values of the hydrolysates were gradually increased. The solubilities of AWGHs were pH-independent over the studied range. Such behavior was explained by the fact that smaller, more hydrophilic and more solvated polypeptide units were produced as a consequence of enzymatic hydrolysis; hence, aggregates were no longer formed, even at the isoelectric pH. 3.3.2 Emulsifying capacity and stability The emulsifying capacities of the hydrolysates were first increased and then decreased with increasing protein hydrolysis, as seen in Fig. 5 . The higher EC value (0.64) obtained for the sample of DH 5% can be attributed to the low level of degradation of wheat gluten molecules by Alcalase. This increased the availability of large peptide units at the oil–water interface, resulting in larger surface area and, consequently, greater emulsion formation ( Puski, 1975 ). With the increase of gluten hydrolysis, the extensive degradation of gluten resulted in the decrease of emulsifying capacity. The trend was similar to that reported in emulsifying properties of salmon muscle protein hydrolysates by Kristinsson and Rasco (2000b) . 3.3.3 Foaming capacity and stability Proteins in dispersions cause a lowering of the surface tension at the water–air interface, thus creating foaming capacity ( Surowka & Fik, 1992 ). Fig. 6 showed a significant increase in the foaming capacity for the DH 5% sample (158% volume increase) compared to the control sample (84.0% increase). This result suggested an increase in surface activity, probably due to the initially greater number of polypeptide chains that arose from partial proteolysis, which allowed more air to be incorporated. An improvement in foaming capacity for enzymatically modified food proteins was reported by Adler-Nissen (1986) . The decrease in foaming of the more extensively hydrolyzed samples, DH 10.0 (115%) and DH 15.0 (90%), suggested an opposite effect on the surface activity, probably due to the lower surfactant activity of smaller polypeptide chains from extensive hydrolysis. The most stable foam was obtained with the DH 5% sample, sustaining 40.0% of the initial foam after the 60 min quiescent period, far beyond the stability of the control sample, which sustained only 9.09% ( Fig. 7 ). Also, the foam stability decreased as the extent of hydrolysis increased. It has been suggested that stable protein foams were obtained from some larger protein components and partially hydrolyzed protein. More extensive hydrolysis increases the number of polypeptide chains which do not have the ability to stabilize the air cells of the foam. 4 Conclusion Compared with digestive enzymes (trypsin, pepsin and pancreatin), Alcalase-assisted hydrolysates of wheat gluten had a high protein recovery (81.3 ± 0.1%). The solubilities of all AWGHs were high at all DH over a wide pH range. And the emulsifying and foaming properties of AWGH with relatively low DH (5.0%) were remarkably higher compared to the original gluten. With the increasing of DH over 5%, the improved solubility did not translate into an improvement of interfacial properties, probably because the peptides generated were too small to stabilize the air/water and oil/water interfaces. Acknowledgement This work was supported by the Specialized Research Fund for the Doctoral Program of Higher Education (No.2004028500) from Educational Ministry of the People’s Republic of China. References Adler-Nissen, 1986 J. Adler-Nissen Enzymic hydrolysis of food proteins 1986 Elsevier Applied Science Publisher New York AOAC, 1990 AOAC Official Methods of Analysis 15th ed. 1990 Association of Official Analytical Chemists Washington, DC, USA Batey, 1985 I.L. Batey Enzymatic solubilization of wheat gluten Journal of Applied Biochemistry 7 1985 423 429 Bernardi Don et al., 1991 L.S. Bernardi Don A.M.R. Pilosof G.B. Bartholomai Enzymatic modification of soy protein concentrates by fungal and bacterial proteases Journal of the American Oil Chemists Society 68 1991 102 105 Bietz and Rothfus, 1970 J.A. Bietz J.A. Rothfus Comparison of peptides from wheat gliadin and glutenin Cereal Chemistry 47 1970 381 392 Bietz and Lookhart, 1996 J.A. Bietz G.L. Lookhart Properties and non-food potential of gluten Cereal Foods World 41 5 1996 376 382 Chobert et al., 1988 J.M. Chobert C. Bertrand-Harb M.G. Nicolas Solubility and emulsifying properties of caseins and whey proteins modified enzymatically by trypsin Journal of Agricultural and Food Chemistry 36 1988 883 886 Cornell and Mothes, 1995 H.J. Cornell T. Mothes Further studies of the in vitro activity of synthetic gliadin peptides in celiac disease Biochimica et Biophysica Acta 1270 1995 168 172 Cornell, 1998 H.J. Cornell Partial in vitro digestion of active gliadin-related peptides in celiac disease Journal of Protein Chemistry 17 8 1998 739 744 Danno and Natake, 1980 G. Danno M. Natake Susceptibility of wheat glutenin to enzymatic hydrolysis Agricultural and Biological Chemistry 44 9 1980 2155 2159 Drago and González, 2001 S.R. Drago R.J. González Foaming properties of enzymatically hydrolysed wheat gluten Innovative Food Science and Emerging Technologies 1 2001 269 273 Galili and Feldman, 1985 G. Galili M. Feldman Structural homology of endosperm high molecular weight glutenin subunits of common wheat ( Triticum aesivum L.) Theoretical and Applied Genetics 70 1985 634 642 Kristinsson and Rasco, 2000a H.G. Kristinsson B.A. Rasco Kinetics of the hydrolysis of Atlantic salmon (Salmo salar) muscle proteins by alkaline proteases and a visceral serine protease mixture Process Biochemistry 36 2000 131 139 Kristinsson and Rasco, 2000b H.G. Kristinsson B.A. Rasco Biochemical and Functional Properties of Atlantic Salmon (Salmo salar) Muscle Proteins Hydrolyzed with Various Alkaline Proteases Journal of Agricultural and Food Chemistry 48 2000 657 666 Huebner et al., 1984 F.R. Huebner K.W. Lieberman R.P. Rubino J.S. Wall Demonstration of high opioid-like activity in isolated peptides from wheat gluten hydrolysates Peptides 5 6 1984 1139 1147 Lens et al., 1999 J.P. Lens W.J. Mulder P. Kolster Modification of wheat gluten for nonfood applications Cereal Foods World 44 1 1999 5 9 Linarès et al., 2000 E. Linarès C. Larré M. Lemeste Y. Popineau Emulsifying and foaming properties of gluten hydrolysates with an increasing degree of hydrolysis: role of soluble and insoluble fractions Cereal Chemistry 77 4 2000 414 420 Masson et al., 1986 P. Masson D. Tomé Y. Popineau Peptic hydrolysis of gluten, glutenin and gliadin from wheat grain: kinetics and characterisation of peptides Journal of the Science of Food and Agriculture 37 1986 1223 1235 Maningart et al., 1999 C.C. Maningart G.K. Demeritt R. Chinnaswamy S.D. Bassi Properties and applications of texturized wheat gluten Cereal Foods World 44 9 1999 650 655 Mimouni et al., 1999 B. Mimouni J.L. Azanza J. Raymond Influence of double enzymic hydrolyses on gluten functionality Journal of the Science of Food and Agriculture 79 1999 1048 1053 Morr et al., 1985 V. Morr B. German J.E. Kinsella J.M. Regenstein J.P. Van Buren A. Kilara A collaborative study to develop a standardized food protein solubility procedure Journal of Food Science 50 1985 1715 1718 Mutilangi et al., 1995 W.A.M. Mutilangi D. Panyam A. Kilara Hydrolysates from proteolysis of heat-denatured whey proteins Journal of Food Science 60 5 1995 1104 1109 Netto and Galeazzi, 1998 F.M. Netto M.A.M. Galeazzi Production and Characterization of Enzymatic Hydrolysate from Soy Protein Isolate Lebensmittel-Wissenschaft und-Technologie 31 1998 624 631 Pearce and Kinsella, 1978 K.N. Pearce J.E. Kinsella Emulsifying properties of food proteins: evaluation of a turbidimetric technique Journal of Agricultural and Food Chemistry 26 1978 716 723 Phillips and Beuchat, 1981 Phillips, R. D., & Beuchat, L. R. (1981). Enzyme modification of proteins. In: Cherry, J.P. (Ed.), Protein functionality in foods , (pp. 275–298). ACS Symposium Series, Washington, DC. Popineau et al., 2002 Y. Popineau B. Huchet C. Larré S. Bérot Foaming and emulsifying properties of fractions of gluten peptides obtained by limited enzymatic hydrolysis and ultrafiltration Journal of Cereal Science 35 2002 327 335 Puski, 1975 G. Puski Modification of functional properties of soy proteins by proteolytic enzyme treatment Cereal Chemistry 52 1975 655 664 Shewry et al., 1984b P.R. Shewry J.M. Field A.J. Faulks S. Parmar B.J. Miflin M.D. Dietler The purification and N-terminal amino acid sequence analysis of the high molecular weight gluten polypeptides of wheat Biochimica et Biophysica Acta 788 1984 23 34 Suetsuna and Chen, 2002 K. Suetsuna J.R. Chen Isolation and characterization of peptides with antioxidant activity derived from wheat gluten Food Science and Technology Research 8 3 2002 227 230 Surowka and Fik, 1992 K. Surowka M. Fik Studies on the recovery of proteinaceous substances from chicken heads. I. An application of neutrase to the production of protein hydrolysate International Journal of Food Science and Technology 27 1992 9 20",
        "keywords": [
            "alcalase",
            "enzymatic hydrolysis",
            "functional property",
            "wheat gluten",
            "food processing"
        ],
        "authors": [
            {
                "name": "KONG Xiang-zhen",
                "org": "Key Laboratory of Food Science and Safety, Ministry of Education; Southern Yangtze University, 170 Huihe Road, Wuxi, 214036 Jiangsu Province, PR China"
            },
            {
                "name": "ZHOU Hui-ming",
                "org": "School of Food Science and Technology, Southern Yangtze University, Wuxi "
            },
            {
                "name": "QIAN Hai-feng",
                "org": "School of Food Science and Technology, Southern Yangtze University, 170 Huihe Road, Wuxi, 214036 Jiangsu Province, PR China"
            }
        ],
        "venue": "Scientia Agricultura Sinica",
        "year": 2007
    },
    "HgLxE34j": {
        "id": "HgLxE34j",
        "title": "New application of partitioning methodology: identity-based dual receiver encryption.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Wen Chen",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2016
    },
    "grSPTW3S": {
        "id": "grSPTW3S",
        "title": "I know where you are: Thwarting privacy protection in location-based social discovery services",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Minhui Xue",
                "org": "east china normal university"
            },
            {
                "name": "Yong Liu",
                "org": "new york university"
            },
            {
                "name": "Keith W. Ross",
                "org": "new york university"
            },
            {
                "name": "Haifeng Qian",
                "org": "new york university shanghai"
            }
        ],
        "venue": "INFOCOM Workshops",
        "year": 2015
    },
    "jagxkLCl": {
        "id": "jagxkLCl",
        "title": "ESTABLISHMENT OF REAL-TIME PCR FOR ANALYZING mRNA ABUNDANCE IN CHLORELLA VULGARIS EXPOSED TO XENOBIOTICS: ESTABLISHMENT OF REAL-TIME PCR FOR ANALYZING mRNA ABUNDANCE IN CHLORELLA VULGARIS EXPOSED TO XENOBIOTICS",
        "abstract": "",
        "keywords": [
            "real time pcr"
        ],
        "authors": [
            {
                "name": "fu zhengwei",
                "org": ""
            },
            {
                "name": "hong jiang",
                "org": ""
            },
            {
                "name": "wei chen",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "xu xiaoyan",
                "org": ""
            }
        ],
        "venue": "Acta Hydrobiologica Sinica",
        "year": 2010
    },
    "JT7dxgKE": {
        "id": "JT7dxgKE",
        "title": "Efficient Pairing-Based Threshold Proxy Signature Scheme with Known Signers",
        "abstract": "Since threshold proxy signature has been proposed, all threshold proxy signature schemes are based on the discrete logarithm problems in the modular multiplicative group which has an element g with a large prime order. Nowadays this kind of threshold proxy signature schemes become more and more complex and time-consuming for security and specific requirement. In this paper, we propose a (bilinear) pairing-based threshold proxy signature scheme with known signers, analyze its security and check the following properties the proposed scheme has: non-repudiation, unforgeability, identifiability, distinguishability, verifiability, prevention of misuse of proxy signing right, etc. Moreover, we point out that the proposed scheme is of great efficiency by comparing it with Sun's and Hsu et al.'s scheme.",
        "keywords": [
            "digital signatures",
            "following property",
            "proxy signature",
            "efficient pairing-based threshold proxy",
            "threshold proxy signature",
            "known signer",
            "cryptography",
            "discrete logarithm problem",
            "signature scheme",
            "pairing-based threshold proxy signature",
            "bilinear pairing.",
            "threshold proxy signature scheme",
            "element g",
            "proposed scheme",
            "great efficiency",
            "proxy signing right",
            "modular multiplication",
            "it security",
            "bilinear",
            "digital signature"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, the People's Republic of China, e-mail: ares@sjtu.edu.cn, cao-zf@cs.sjtu.edu.cn,  ..."
            },
            {
                "name": "Zhenfu Cao",
                "org": "(Corresponding author) Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, the People's Republic of China, e-mail: ares@sjtu.edu.cn,  ..."
            },
            {
                "name": "Qingshui Xue",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, the People's Republic of China, e-mail: ares@sjtu.edu.cn, cao-zf@cs.sjtu.edu.cn,  ..."
            }
        ],
        "venue": "Informatica, Lith. Acad. Sci.",
        "year": 2005
    },
    "1NDZGJwS": {
        "id": "1NDZGJwS",
        "title": "An ECDLP-Based Threshold Proxy Signature Scheme Using Self-Certified Public Key System",
        "abstract": "In a (t, n) threshold proxy signature scheme, one original signer delegates a group of n proxy signers to sign messages on behalf of the original signer. When the proxy signature is created, at leastt proxy signers cooperate to generate valid proxy signatures and any less than t proxy signers can’t cooperatively generate valid proxy signatures. So far, all of proposed threshold proxy signature schemes\n are based on public key systems with certificates, which have some disadvantages such as checking the certificate list when\n needing certificates. Most threshold proxy signature schemes use Shamir’s threshold secret share scheme. Identity-based public\n key system is not pretty mature. Self-certified public key systems have attracted more and more attention because of its advantages.\n Based on Hsu et al’s self-certified public key system and Li et al’s proxy signature scheme, one threshold proxy signature\n scheme based on ECDLP and self-certified public key system is proposed. As far as we know, it is the first scheme based on\n ECDLP and self-certified public key system. The proposed scheme can provide the security properties of proxy protection, verifiability,\n strong identifiability, strong unforgeability, strong repudiability, distinguishability, known signers and prevention of misuse\n of proxy signing power. That is, internal attacks, external attacks, collusion attacks, equation attacks and public key substitution\n attacks can be resisted. In the proxy signature verification phase, the authentication of the original and the proxy signers’\n public keys and the verification of the threshold proxy signature are executed together. In addition, the computation overhead\n and communication cost of the proposed scheme are analyzed as well.\n ",
        "keywords": [
            "public key"
        ],
        "authors": [
            {
                "name": "Qingshui Xue",
                "org": "Shanghai Jiao Tong University School of Techniques 201101 Shanghai China"
            },
            {
                "name": "Fengying Li",
                "org": "Shanghai Jiao Tong University School of Techniques 201101 Shanghai China"
            },
            {
                "name": "Yuan Zhou",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China Beijing 100029 China"
            },
            {
                "name": "Jiping Zhang",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China Beijing 100029 China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong University Dept. of Computer Science and Engineering 200240 Shanghai China"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University Dept. of Computer Science and Technology 200062 Shanghai China"
            }
        ],
        "venue": "MobiSec",
        "year": 2009
    },
    "sT6sggLz": {
        "id": "sT6sggLz",
        "title": "Effects of atrazine on photosynthesis and defense response and the underlying mechanisms in Phaeodactylum tricornutum",
        "abstract": "Atrazine (ATZ) is a commonly used herbicide that has recently come under scrutiny due to potential environmental toxicity and contamination. In this study, we found that the administration of ATZ indeed leads to reduction of photosynthesis and oxidative stress in Phaeodactylum tricornutum at the treated doses higher than 100 μg L−1 after 48 h. We further explored the effect of ATZ on photosystem II (PSII) and gene expression of electron transport chain. Collectively, our results may suggest that ATZ entered the chloroplasts in alga depending on ATZ’s liposolubility and directly attacked on the electron transport chain, especially PSII, contributing to reactive oxygen species (ROS) burst. The increasing ROS could act as signals to induce or disturb the expression of photosynthesis-related genes, resulting in the imbalance of antioxidation and pro-oxidation in the alga.",
        "keywords": [
            "Phaeodactylum tricornutum",
            " ATZ",
            " Real-time PCR",
            " Electron transport"
        ],
        "authors": [
            {
                "name": "xiaocui bai",
                "org": "zhejiang university of technology"
            },
            {
                "name": "chongchong sun",
                "org": "zhejiang university of technology"
            },
            {
                "name": "jun xie",
                "org": "zhejiang university of technology"
            },
            {
                "name": "hao song",
                "org": "zhejiang university of technology"
            },
            {
                "name": "qianqian zhu",
                "org": "zhejiang university of technology"
            },
            {
                "name": "yiyuan su",
                "org": "zhejiang university of technology"
            },
            {
                "name": "haifeng qian",
                "org": "chinese academy of sciences"
            },
            {
                "name": "zhengwei fu",
                "org": "zhejiang university of technology"
            }
        ],
        "venue": "Environmental Science and Pollution Research",
        "year": 2015
    },
    "nlcNH1Aq": {
        "id": "nlcNH1Aq",
        "title": "Impact of 1998–2002 midlatitude drought and warming on terrestrial ecosystem and the global carbon cycle",
        "abstract": "A rare drought occurred from 1998 to 2002 across much of the Northern Hemisphere midlatitude regions. Using observational data and numerical models, we analyze the impact of this event on terrestrial ecosystem and the global carbon cycle. The biological productivity in these regions was found to decrease by 0.9 PgC yr−1 or 5% compared to the average of the previous two decades, in conjunction with significantly reduced vegetation greenness. The drought led to a land carbon release that is large enough to significantly modify the canonical tropically dominated ENSO response. An atmospheric inversion reveals that during the 1998–2002 drought period, Northern Hemisphere midlatitude changed from a 1980–1998 average of 0.7 PgC yr−1 carbon sink to nearly neutral to the atmosphere, while a forward model suggests a change of 1.3 PgC yr−1 in the same direction. This large CO2 source may explain the consecutive large increase in atmospheric CO2 growth rate of about 2 ppmv yr−1 in recent years, as well as the anomalous timing of events. This Northern Hemisphere CO2 anomaly was largely caused by reduced vegetation growth due to less precipitation, but also with significant contribution from higher temperature that directly increases respiration loss and indirectly further reduces soil moisture. Since the Northern Hemisphere midlatitude landscape has been significantly modified by agriculture, grazing, irrigation and fire suppression, the strong signature in the global carbon cycle of a drought initiated by changes in tropical oceanic temperatures is a remarkable manifestation of climate variability, with implications for carbon cycle response and feedback to future climate change.",
        "keywords": [
            "global carbon cycle",
            "system modeling",
            "climate change",
            "carbon cycle",
            "soil moisture",
            "vegetative growth",
            "water cycle",
            "remote sensing",
            "biogeochemical cycle",
            "global change",
            "fire suppression",
            "carbon sink",
            "terrestrial ecosystems"
        ],
        "authors": [
            {
                "name": "Ning Zeng",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Christian Roedenbeck",
                "org": ""
            },
            {
                "name": "Martin Heimann",
                "org": ""
            }
        ],
        "venue": "Geophysical Research Letters",
        "year": 2005
    },
    "orJDyVdo": {
        "id": "orJDyVdo",
        "title": "Effects of different additives on rice cake texture and cake staling",
        "abstract": "MiGao, prepared from rice flour and sticky rice flour, is a kind of steam cooked Chinese cake. The purpose of this work was to evaluate the effect of different additives (carboxylmethyl cellulose [CMC], xanthan, β-amylase and α-amylase) on the MiGao quality during storage for 0, 1, 3 and 5 days at room temperature (25C). MiGao texture was determined by measure the hardness of MiGao crumb during storage. Differential scanning calorimetry (DSC) was used to follow changes of starch retrogradation in MiGao crumb. Among the preparations supplemented with additives as determined by texture and DSC measurements, followed the order of β-amylase > CMC > xanthan. In general, except when α-amylase was used, the overall acceptability of MiGao was always improved by the addition of additives. The simultaneous analysis of the firming and starch retrogradation results revealed that the anti-staling effect of additives might be due to the retardation in the starch retrogradation. © 2010 Wiley Periodicals, Inc.",
        "keywords": [
            "additive",
            "differential scanning calorimetry",
            "rice cake",
            "staling",
            "texture"
        ],
        "authors": [
            {
                "name": "Ying Ji",
                "org": "Dalian Nationalities University(Dalian Nationalities University),Dalian,China"
            },
            {
                "name": "Kexue Zhu",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Zhicheng Chen",
                "org": "Henan University of Technology(Henan University of Technology),Zhengzhou,China"
            },
            {
                "name": "Huiming Zhou",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Jiaxi Ma",
                "org": "Dalian Nationalities University(Dalian Nationalities University),Dalian,China"
            },
            {
                "name": "HaiFeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "Journal of Texture Studies",
        "year": 2010
    },
    "kuC3plno": {
        "id": "kuC3plno",
        "title": "Forward Secure Public Key Encryption with Keyword Search for Outsourced Cloud Storage",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Ming Zeng",
                "org": ""
            },
            {
                "name": "Hai-Feng Qian",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            }
        ],
        "venue": "IEEE Transactions on Cloud Computing",
        "year": 2019
    },
    "cKEedrnU": {
        "id": "cKEedrnU",
        "title": "Gate movement for timing improvement on row based Dual-VDD designs.",
        "abstract": "The scale of technology node increases power-density dynamically. Various techniques are proposed to reduce the power consumption. One approach is Dual-Supply Voltage (DSV).DSV is to apply a lower supply voltage on selected non-critical gates for power saving while maintaining chip performance at the same time. In order to facilitate the power design in DSV, the same voltage gates are grouped to form islands. [21] presents a flow to generate and place voltage islands. However, after relocating gates to voltage islands, the original placement is changed and the timing might become worse. In this paper, we propose algorithms to redistribute gates for performance improvement. At the same time, all the DSV island/gate constraints are satisfied. On tested designs, our algorithm greatly improved the timing, and the final worst slack is less than 10ps worse than that of the original design.",
        "keywords": "",
        "authors": [
            {
                "name": "Hua Xiang",
                "org": ""
            },
            {
                "name": "Lakshmi N. Reddy",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Ching Zhou",
                "org": ""
            },
            {
                "name": "Yu-Shiang Lin",
                "org": ""
            },
            {
                "name": "Fanchieh Yee",
                "org": ""
            },
            {
                "name": "Andrew Sullivan",
                "org": ""
            },
            {
                "name": "Pong-Fei Lu",
                "org": ""
            }
        ],
        "venue": "ISQED",
        "year": 2016
    },
    "M1UHZmUM": {
        "id": "M1UHZmUM",
        "title": "Microbiological characteristics of cake prepared from rice flour and sticky rice flour",
        "abstract": "Microbiological, chemical and sensory changes in MiGao (a traditional Chinese steamed cake) were studied during five days of storage at 25 °C. Microorganisms examined for were: Enterobactericeae, lactic acid bacteria, Gram-positive, catalase-positive cocci, Staphylococcus aureus , Bacillus strains, yeasts and moulds, and pH and moisture content were also analyzed. Total plate counts in the products under study in the third day of storage were in the range <10 3 CFU/g and the shelf-life of the product was estimated to be only two or three days by the panelists. During the first two days, Gram-positive bacteria were dominant, mainly represented by Staphylococcus epidermidis . Bacillus strains occurred by the third day, reaching a maximum level of 1 × 10 6 CFU/g after five days of storage. No Enterobactericeae or Lactic acid bacteria were detected in the processed products throughout the storage period. All the isolated strains from the mannitol salt agar belonged to the genus Staphylococcus . The predominant species were S. epidermidis and S. aureus. Most Bacillus strains, isolated from the tryptone soya agar, belonged to the species Bacillus brevis . The count of yeasts and moulds increased slowly but remained low throughout the storage period. Keywords MiGao Microbiology Staphylococcus Bacillus 1 Introduction A small segment of the world population suffers from celiac disease. The responsible pathogenic factor has been traced to the gliadin fraction of gluten. The only effective treatment for coeliac disease is a strict adherence to a gluten free diet throughout the patient’s lifetime, which, in time, results in clinical and mucosal recovery ( Gallagher, Gormley, & Arendt, 2004 ). Rice has properties such as the absence of gluten, low levels of sodium, protein, fat and fibre, and a high amount of easily digested carbohydrates, which are desirable for certain special diets. Rice is one of the leading food crops in South East Asia including China, and the production of rice in this part of the world is much higher than that of wheat. It can be ground into powder and utilized to produce many kinds of foods, including several types of cake. Sticky rice has properties genetically different from the non-sticky variety, such as its lack of amylose in the starch and with abundant amylopectin starch. MiGao is one of the most widespread of these types of cake ( Fig. 1 ). This kind of cake is a steam cooked traditional Chinese food prepared from rice powder and sticky rice powder (in the ratio of 1:3) by steaming in a bamboo steamer ( Fig. 2 ). It is famous for its soft and sticky texture and is usually served as a dessert. With abundant nutrients, water activity of 0.92, and almost neutral pH of 6.7, MiGao can be considered a good medium for microbial growth. Microbial spoilage is the major problem causing deterioration of products but there is also a problem with physiological spoilage such as enzymic spoilage. The bacterial numbers were over 10 3 CFU/g, even if bacteria were not detected (<10 CFU/g) in the initial product analysis. Post-process contamination from the atmosphere or from surfaces during the steaming, finishing and wrapping procedures is unavoidable. Many workers have examined different aspects of MiGao production. Particular attention has been given to the various aspects such as process variations and preservation, and nutritional improvement ( Fu, Feng, & Lin, 2003; Peng & Luo, 2004 ). Nowadays, producers of MiGao are interested in extending the shelf life of this product in order to increase the potential market and satisfy consumer demands. The aim of this study was to investigate the evolution of the different categories of the microorganisms in MiGao and discuss their interactions, to identify and characterize the desirable groups (Bacilli and cocci), in order to select the most suitable strains, according to their technological properties and antimicrobial activity against foodborne pathogens, as starter or protective cultures. 2 Materials and methods 2.1 Preparation of the MiGao and sampling schedule Rice flour and sticky rice flour were obtained from the local market. MiGao was made from 180 g sticky rice flour; 120 g rice flour and 60 g sucrose. Ingredients were mixed with water and shaped by a mold, and then steamed in a bamboo steamer for 15–20 min. After cooling for 10 min the Migao samples packaged in polyethylene bags. These trials were repeated three times during the duration of the study. MiGao have a thickness of approximately 1.5 cm and diameter of 60 cm 2 . Freshly steamed MiGao are soft, pliable and elastic. 2.2 Storage and sampling After cooling, the processed product was stored at 25 °C, for up to five days and temperatures monitored on a daily basis throughout the storage period. The microbiological quality of raw materials was determined on the day of receipt and a microbiological analysis and sensory evaluation carried out on the processed product on the day of production and at daily intervals during the storage period. 2.3 Microbiological analysis On each sampling day, three packages were analysed. A 10 g portion of minced sample was aseptically weighed into 90 ml of physiological saline (0.85% NaCl) in a sterile plastic bag and blended in a stomacher for 2 min. After 30 min at room temperature, serial decimal dilutions in linger solution were prepared and 1 or 0.1 ml samples of appropriate dilutions were poured or spread on non-selective and selective agar plates. Total plate counts were determined on plate count agar pour plates and enumerated after an incubation period of 48–72 h at 30 °C. The number of Enterobacteriaceae was determined using a pour plate method on Violet Red Bile Glucose Agar at 37 °C for 24 h. Lactic acid bacteria were inoculated into de Man–Rogosa–Sharpe agar at 30 °C for five days. Populations of Gram-positive, catalase-positive cocci were determined by surface plating samples on mannitol salt agar followed by incubation at 30 °C for 72 h, Staphylococcus aureus was determined by Baird-Parker agar incubated at 37 °C for 48 h. Bacillus strains were inoculated into tryptone soya agar at 30 °C for 24 h. Yeasts and molds populations were determined by surface plating sample on potato dextrose agar at 30 °C for seven days. 2.4 Identification of strains On each sampling day, 30 and 15 isolates (10 and 5 for each of the three samples) were randomly selected by picking colonies respectively from MSA, BP and TSA plates of highest dilution showing growth. The 270 isolates obtained were purified three times on MSA, BP and TSA plates and characterized morphologically by phase contrast microscopy and examined for motility, and for Gram reaction and catalase activity by dropping a 3% H 2 O 2 solution directly onto each plate. For the presumptive cocci strains, tests were performed at 30 °C. The isolates were subjected to the following tests: sensitivity to novobiocin, production of ammonia from urea, coagulase production, β-galactosidase activity, oxidase reaction, nitrate reduction, acetoin formation ( Baird-Parker, 1979 ) and fermentation of the following sugars: maltose, mannitol, mannose, lactose, l -arabinose, sucrose, raffinose, cellobiose, trehalose and d -xylose according to Sharp (1979) . For the presumptive Bacillus strains, tests were performed at 30 °C. Bacillus strains were identified with the standard tests and classification schemes described by Balows, Truper, Dworkin, Harder, and Schleifer (1992) and Claus and Berkeley (1986) . The following characteristics were determined: morphology, anaerobic growth, utilization of citrate and propionate, hydrolysis of casein, production of acetoin, reduction of nitrate, formation of dihydroxyacetone, growth at 50 and 65 °C, growth at 7% NaCl, Voges–Proskauer (V–P) test, catalase activity, and fermentation of carbohydrates. 2.5 Chemical analysis Moisture content was determined by the AACC moisture procedure 44–15A (2000). The pH was determined using a pH meter (PHS-3C, Ruili Analysis Instrument Company, Shanghai, China). 2.6 Sensory analysis Sensory evaluation carried out on the product on the day of production and at daily intervals during the storage period. Ten panelists gave a score between 1 and 9 for tenderness, colour, texture, flavour and overall acceptability and a mean score was estimated for each product. 3 Results Table 1 shows the microbiological analysis of the different groups during storage at 25 °C for five days. Populations of microorganisms increased overtime. Total plate counts in the products under study in the third day of storage at 25 °C were in the range <10 3 CFU/g, all under the maximum 10 3 CFU/g specification in the PR China Department of Health and Chinese guidelines. The shelf life is determined by the total plate counts according to the PR China Department of Health and Chinese guidelines. Although the bacterial counts were initially <10 CFU/g, this increased to 6 × 10 6 CFU/g after five days of storage. Populations of cocci on MiGao increased quickly for the first three days of storage, reaching a maximum level of 7 × 10 4 CFU/g. Bacillus strains, which were in the minority at the beginning increased to 2 × 10 4 CFU/g during the four days and reached a maximum after five days of storage. The yeasts and moulds counts increased slowly but remained low throughout the storage period. No Enterobactericeae and Lactic acid bacteria were detected in the processed products throughout the storage period. The chemical results are presented in Table 2 . The pH was fairly stable during storage, slowly declining from 6.70 to 6.66. MiGao moisture decreased sharply with time. The freshly cooked MiGao contained about 39.5% moisture. However, during two days of storage the moisture dropped to 28.4%. With additional storage time the moisture continued to decrease, but at a slow rate. In the course of storage, the moisture migrates from the crumb toward the crust and evaporates from the surface of the product ( Piazza & Masi, 1995 ). The result of sensory analyses demonstrated that storage for two days did not modify the sensory characteristics of the standard. After two days the MiGao were became more hard in texture and taste scores were lower (results not shown). The more detailed taxonomic studies for the Gram-positive bacteria, identified according to Sharp (1979) and Claus and Berkeley (1986) showed that during storage, staphylococci were initially dominant bacterial ( Table 1 ). They were present throughout the storage period however, after three days of storage, a group of large Gram-positive bacilli became important, and eventually dominated the microflora. All of the 206 gram-positive, catalase-positive cocci strains isolated from MiGao belonged to the genus Staphylococcus ( Table 3 ). In accordance with the separation of staphylococci and Kocuria proposed by Schleifer and Kloos (1975) , the staphylococci strains were able to grow in the presence of novobiocin, were lysozyme resistant and lysostaphin sensitive. The staphylococcal isolates were susceptible to novobiocin, 80% were coagulase-negative, thus belonged to the S. epidermidis group, whilst 20% were coagulase-positive; all coagulase-positive stains produced acid from mannitol anaerobically, as only S. aureus does ( Kloos, 1990 ). After three days of storage, a group of large Gram-positive bacilli became important. For identification of the bacilli, 115 isolates from TSA plates were examined. Based on our tests, two groups were found ( Table 4 ), tentatively identified according to Claus and Berkeley (1986) . One of the bacilli strains produced acid from glucose, but not from xylose. All strains of this group grew at 50 °C but failed to grow in 7% NaCl, According to Balows et al. (1992) , they were tentatively identified as Bacillus brevies . The other strains produced acid from glucose, and the sporangium was not swollen. All strains of this group grew in 7% NaCl indicating that they belong to Bacillus subtilis. Claus and Berkeley (1986) . 4 Discussion The rate of microbial growth in MiGao was very rapid during the five days storage. Although the total viable counts were still increasing rapidly at five days, the product was completely spoiled after only three days of storage. The high water content and higher water activity values in MiGao may play an important role in controlling the growth of bacteria. Gram-positive bacteria were dominant species during storage. During the first three days, Staphylococci were the dominant bacterial group. Occurrence of S. epidermidis at the beginning is not surprising, probably entering due to human manipulation during manufacturing of MiGao since they are the most prevalent species found on normal human skin and are isolated occasionally from the skin of domestic animals ( Schleifer, 1986 ). The bacilli strains eventually became the dominant microorganisms. The water activity, pH and temperature during storage may play important roles in spore germination and growth of vegetative cells of Bacillus spp ( Condon, Palop, Raso, & Sala, 1996; Quintavalla & Parolari, 1993 ). B. brevis and B. subtilis were found. It was not widely represented during the first two days of storage. The dominance of B. brevis and B. subtilis in MiGao could be explained by the higher resistance to heat. These aerobic, rod-shaped, spore-forming bacteria are incorporated into MiGao dough by flour contaminated with bacterial spores ( Pattison, Lindsay, & Vonholy, 2003 ). Spores that are not killed during steaming in a bamboo steamer subsequently germinate and grow. Studies of the thermal resistance of Bacillus strains indicated a need for controlling survival and growth of B. brevis and B. subtilis in MiGao. The usual recommended control procedures such as stringent temperature control during cooking and testing of raw materials ( Bailey & Von Holy, 1993 ) can reduce the initial spore counts in dough, but not prevent germination and growth in MiGao. Bacterial survival processing of foods depended on pH, a w and other micro-environmental factors ( Condon, Lopez, Oria, & Sala, 1989 ). The work described in this article aimed at detection of rope spoilage, performed directly with MiGao samples, allowed isolation of different strains of spoilage-causing bacteria. The potential hazard of the presence of Bacilli and cocci in food or food ingredients should not, therefore, be ignored. In addition, new formulations should be assessed individually, as an ingredient may alter the shelf life or safety aspect considerably. Aspects that require further investigation include the formulation of products for improved microbial safety during storage (e.g. combined pH, temperature and natural preservatives). References Bailey and Von Holy, 1993 C.P. Bailey A. Von Holy Bacillus spore contamination associated with commercial bread manufacture Food Microbiol 10 1993 287 294 Baird-Parker, 1979 A.C. Baird-Parker Methods for identifying staphylococci and micrococci F.A. Skinner P.W. Lovelock Identification methods for microbiologists 1979 Academic London 201 210 Balows et al., 1992 A. Balows H.G. Truper M. Dworkin W. Harder K.H. Schleifer The Prokaryotes 2nd ed. A handbook on the biology of bacteria: Ecophysiology, isolation, identification, applications Vol. I–IV 1992 Springer New York Claus and Berkeley, 1986 D. Claus R.C.W. Berkeley Genus Bacillus Colin 1872, 174 P.H.A. Sneath N.S. Mair M.E. Sharpe J.G. Holt Bergey’s Manual of Systematic Bacteriology Vol. 2 1986 Williams and Wilkins Baltimore, MD 1043 1071 Condon et al., 1989 S. Condon P. Lopez R. Oria F.J. Sala Thermal death determination: design and evaluation of a thermoresistometer Journal of Food Science 54 1989 451 457 Condon et al., 1996 S. Condon A. Palop J. Raso F.J. Sala Influence of the incubation temperature after heat treatment upon the estimated heat resistance values of spores of Bacillus subtilis Letters in Applied Bacteriology 22 1996 149 152 Fu et al., 2003 X.W. Fu F.Q. Feng M.F. Lin Experimental study on the compound quality improver of sticky rice-products Transactions of The Chinese Society of Agricultural Engineering 4 2003 212 215 Gallagher et al., 2004 E. Gallagher T.R. Gormley E.K. Arendt Recent advances in the formulation of gluten-free cereal-based products Trends in Food Science and Technology 15 2004 143 152 Kloos, 1990 W.E. Kloos Systematics and the natural history of staphylococci 1 J. Appl. Bacteriol. Symp. Suppl. 69 1990 25S 37S Pattison et al., 2003 T.L. Pattison D. Lindsay A. Vonholy In vitro growth response of bread-spoilage Bacillus strains to selected natural antimicrobials Journal of Basic Microbiology 43 2003 341 347 Peng and Luo, 2004 S.S. Peng X.B. Luo The application of deoxidizer in storing cake Packaging Engineering China 4 2004 147 148 Piazza and Masi, 1995 L. Piazza P. Masi Moisture distribution throughout the bread loaf during staling and its effect on mechanical properties Cereal Chemistry 73 1995 320 325 Quintavalla and Parolari, 1993 S. Quintavalla G. Parolari Effects of temperature, aw and pH on the growth of Bacillus cells and spores: a response surface methodology study International Journal of Food Microbiology 19 1993 207 216 Schleifer, 1986 K.H. Schleifer Gram positive cocci P.H.A. Sneath N.S. Mair M.E. Sharpe J.G. Holt Bergey’s manual of systematic bacteriology 1986 Williams and Wilkins Baltimore 999 1003 Schleifer and Kloos, 1975 K.H. Schleifer W.E. Kloos A simple test for separation of staphylococci from micrococci Journal of Clinical Microbiology 1 1975 337 338 Sharp, 1979 M.E. Sharp Identification of the lactic acid bacteria F.A. Skinner D.W. Lovelock Identification methods for microbiologists 1979 Academic Press London 233 259",
        "keywords": [
            "bacillus",
            "microbiology",
            "migao",
            "staphylococcus",
            "moisture content",
            "shelf life"
        ],
        "authors": [
            {
                "name": "Ying Ji",
                "org": "School of Food Science and Technology, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Kexue Zhu",
                "org": "School of Food Science and Technology, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Huiming Zhou",
                "org": ""
            }
        ],
        "venue": "Food Control",
        "year": 2007
    },
    "gchDRtGu": {
        "id": "gchDRtGu",
        "title": "Effect of soaking and cooking on structure formation of cooked rice through thermal properties, dynamic viscoelasticity, and enzyme activity.",
        "abstract": "The quality of cooked rice and its influence factors have always been the focus of researches. However, the formative mechanisms of its eating quality and structural changes of rice during cooking have seldom been evaluated. In this study, sectional real-time cooking was performed by differential scanning calorimetry (DSC) and dynamic viscoelasticity analysis to monitor the phase transitions and mechanical changes of kernels, which exhibited different characteristics in different stages. Both glass transition and pasting behavior were captured, and showed more viscoelasticity of cooked rice at higher soaking temperatures. Meanwhile, the enzyme activity of rice during soaking was successfully measured by a rapid viscosity analyzer (RVA). Along with the differences of morphologies and crystalline structure at different soaking conditions, the findings of DSC and rheometer were further verified. This study provides effective methods to evaluate changes in rice during cooking and explains the mechanism of differences formed by the soaking temperature.",
        "keywords": [
            "Enzyme effect",
            "Mechanical behavior",
            "Phase transition",
            "Rice",
            "Soaking"
        ],
        "authors": [
            {
                "name": "Ling Zhu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Lilin Cheng",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China. Electronic address: zhanghui@jiangnan.edu.cn."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "2jh0Xo6K": {
        "id": "2jh0Xo6K",
        "title": "In-orbit response versus scan-angle (RVS) validation for the GOES-16 ABI solar reflective bands.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2018
    },
    "0HHbfajR": {
        "id": "0HHbfajR",
        "title": "Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in : IM-induced inhibition of key genes regulating anther and pollen biosynthesis",
        "abstract": "Understanding how herbicides affect plant reproduction and growth is critical to develop herbicide toxicity model and refine herbicide risk assessment. Although our knowledge of herbicides toxicity mechanisms at the physiological and molecular level in plant vegetative phase has increased substantially in the last decades, few studies have addressed the herbicide toxicity problematic on plant reproduction. Here, we determined the long-term (4-8 weeks) effect of a chiral herbicide, imazethapyr (IM), which has been increasingly used in plant crops, on floral organ development and reproduction in the model plant Arabidopsis thaliana. More specifically, we followed the effect of two IM enantiomers (R- and S-IM) on floral organ structure, seed production, pollen viability and the transcription of key genes involved in anther and pollen development. The results showed that IM strongly inhibited the transcripts of genes regulating A. thaliana tapetum development (DYT1: DYSFUNCTIONAL TAPETUM 1), tapetal differentiation and function (TDF1: TAPETAL DEVELOPMENT AND FUNCTION1), and pollen wall formation and developments (AMS: ABORTED MICROSPORES, MYB103: MYB DOMAIN PROTEIN 103, MS1: MALE STERILITY 1, MS2: MALE STERILITY 2). Since DYT1 positively regulates 33 genes involved in cell-wall modification (such as, TDF1, AMS, MYB103, MS1, MS2) that can catalyze the breakdown of polysaccharides to facilitate anther dehiscence, the consistent decrease in the transcription of these genes after IM exposure should hamper anther opening as observed under scanning electron microscopy. The toxicity of IM on anther opening further lead to a decrease in pollen production and pollen viability. Furthermore, long-term IM exposure increased the number of apurinic/apyrimidinic sites (AP sites) in the DNA of A. thaliana and also altered the DNA of A. thaliana offspring grown in IM-free soils. Toxicity of IM on floral organs development and reproduction was generally higher in the presence of the R-IM enantiomer than of the S-IM enantiomer. This study unraveled several IM toxicity targets and mechanisms at the molecular and structural level linked to the toxicity of IM trace concentrations on A. thaliana reproduction.",
        "keywords": [
            "Arabidopsis thaliana",
            "Imazethapyr",
            "Floral organs",
            "Enantiomer",
            "Reproduction"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of ChinaCollege of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Yali Li",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Chongchong Sun",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit,Université Laval,Quebec,Canada"
            },
            {
                "name": "Jun Xie",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiaocui Bai",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Ecotoxicology (London, England)",
        "year": 2015
    },
    "HusyXga7": {
        "id": "HusyXga7",
        "title": "Inhibitory effects of tributyl phosphate on algal growth, photosynthesis, and fatty acid synthesis in the marine diatom Phaeodactylum tricornutum.",
        "abstract": "The widely used solvent extractant, tributyl phosphate (TBP), primarily used as a solvent for the conventional processing of nuclear fuel, has come under scrutiny recently due to concerns surrounding potential environmental contamination and toxicity. In this study, we found that, in Phaeodactylum tricornutum, administration of TBP severely inhibited algal cell growth by reducing photosynthetic efficiency and inducing oxidative stress. We further explored the effect of TBP by examining the gene expression of the photosynthetic electron transport chain and its contribution to reactive oxygen species (ROS) burst. Our data revealed that TBP affected both fatty acid content and profile by regulating the transcription of genes related to glycolysis, fatty acid biosynthesis, and β-oxidation. These results demonstrated that TBP did in fact trigger the synthesis of ROS, disrupting the subcellular membrane structure of this aquatic organism. Our study brings new insight into the fundamental mechanism of toxicity exerted by TBP on the marine alga P. tricornutum.",
        "keywords": [
            "Electron transfer chains",
            "Fatty acid",
            "Gene transcript",
            "Phaeodactylum tricornutum",
            "Tributyl phosphate"
        ],
        "authors": [
            {
                "name": "Hao Song",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Guangfu Liu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xingxing Li",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Yuzhu Tan",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China. hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental science and pollution research international",
        "year": 2016
    },
    "9CqBoupe": {
        "id": "9CqBoupe",
        "title": "Influence of the degree of hydrolysis (DH) on antioxidant properties and radical-scavenging activities of peanut peptides prepared from fermented peanut meal",
        "abstract": "To study the influence of degree of hydrolysis (DH) on antioxidant properties of peanut peptides, the peanut meal was fermented\n by Bacillus subtilis. The fermentation time was 48, 72, and 96 h, respectively, to prepare peanut peptides at different degree of hydrolysis.\n The peanut peptides (11.18, 16.20, and 21.41% of DH, respectively) were extracted from fermentation liquid. The antioxidant\n properties of these peanut peptides were evaluated based on DPPH· radical (1,1-Diphenyl-2-picrylhydrazyl radical) scavenging activity, superoxide anion-scavenging activity, reducing power,\n metal-chelating activity, and inhibition of linoleic acid autooxidation. Peanut peptides (21.41% of DH) at 1 mg/mL exhibited\n 80.86 and 29.35% of scavenging concentration percent on DPPH· and superoxide anion radical, respectively. In addition, the reducing power of peanut peptides was 0.368 at 2 mg/mL, and\n they possessed 76.32% of Fe2+-chelation ability at 2 mg/mL and 63.75% of inhibition of linoleic acid autooxidation at 0.8 mg/mL. The antioxidant activities\n of the peanut peptides (21.41% of DH) were stronger compared with others (11.18 and 16.20% of DH), and this indicated the\n antioxidant activities of peanut peptides increased with increasing DH (p < 0.05). To know much about the peanut peptides, they were subjected to amino acid analysis and determination of molecular\n weight distribution. Some acidic amino acids and essential amino acids were found, and the average molecular weight distributions\n were concentrated in <1,400 Da (86.96%). Combined with the results of the amino acid profiles, the peanut peptides were believed\n to have high nutritive value besides antioxidant activities.",
        "keywords": [
            "degree of hydrolysisantioxidant propertiespeanut mealbacillus subtilis � fermentationmolecular weight"
        ],
        "authors": [
            {
                "name": "Youwei ZhangHui",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            },
            {
                "name": "Xiaona Guo",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, China"
            }
        ],
        "venue": "",
        "year": 2011
    },
    "TT7fTWWa": {
        "id": "TT7fTWWa",
        "title": "Combined effect of copper and cadmium on Chlorella vulgaris growth and photosynthesis-related gene transcription.",
        "abstract": "Chlorella vulgaris was tested to assess their toxicities in freshwater contaminated by the metal compounds of copper (Cu) and cadmium (Cd), both singly and combined. Exposure to 0.5 and 1.5μM Cu or 1.0 and 2.0μM Cd alone significantly decreased algal growth and chlorophyll content and increased reactive oxygen species (ROS) content. Two-way ANOVA analysis shows that the combination of these two metal compounds decreased cell growth, chlorophyll content and increased ROS content synergistically. The highest algal cell inhibition was 78.55%, the lowest levels of chl a, chl b and total-chl were 10.59%, 33.33% and 17.94% of the control, respectively. The highest increase in ROS was 9.15-fold greater than that of the control when exposed to Cu(1.5)+Cd(2.0). Real-time PCR shows that Cu and Cd reduced the transcript abundance of psbA and rbcL, but without a synergistic interaction, whereas Cu and Cd increased the transcript abundance of psaB synergistically. These results demonstrate that Cu and Cd independently inhibit PSII activity and CO2 assimilation, but synergistically increase ROS content to disrupt chlorophyll synthesis and inhibit cell growth.",
        "keywords": [
            "Copper",
            "Cadmium",
            "Interaction",
            "ROS",
            "Gene transcription"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Jingjing Li",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Wei Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "G Daniel Sheng",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Corresponding author. Tel.: +86 571 8832 0599; fax: +86 571 8832 0599."
            }
        ],
        "venue": "Aquatic Toxicology",
        "year": 2009
    },
    "jpnrDSt0": {
        "id": "jpnrDSt0",
        "title": "Regular local clock buffer placement and latch clustering by iterative optimization",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ruchir puri",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "chin ngai sze",
                "org": ""
            },
            {
                "name": "j warnock",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "spLPCkRm": {
        "id": "spLPCkRm",
        "title": "Proteins Extracted from Defatted Wheat Germ: Nutritional and Structural Properties",
        "abstract": "Cereal Chem. 83(1):69-75 The main by-product of the wheat germ oil extraction process is a defatted wheat germ meal, which has a relatively high protein content, making it an attractive and promising source of vegetable proteins. Four protein fractions (albumin, globulin, prolamine, and glutelin) and protein isolate from defatted wheat germ flour (DWGF) were fractionated and then characterized by amino acid analysis, SDS-PAGE, and differential scanning calorimetry (DSC). Albumin was the major fraction (34.5%) extracted, followed by globulin (15.6%), glutelin (10.6%), and prolamine (4.6%). Protein isolate was mainly composed of albumin and globulin. These protein fractions and protein isolate showed an excellent balance of all essential amino acids, with a relatively high level of glutamic acid, arginine, leucine, and glycine, whereas cystine was lacking. All the esti- mated nutritional quality parameters based on amino acids composition showed that defatted wheat germ proteins had good nutritional quality. Nonreduced and reduced SDS-PAGE analyses showed that S-S bonds were deficient in the structure of wheat germ proteins. The albumin fraction consisted of 19 major polypeptide bands with Mr 14,000-84,000. The globulin fraction showed four distinct polypeptides or polypeptide group bands with Mr 55,000, 37,000-43,000, 24,000, and 12,000-20,000, which may be the components of the 8S-type and 11S-like proteins. The prolamine fraction showed a predominant doublet-like band at Mr 17,000-16,000, while the glutelin fraction showed five major polypeptide bands with Mr 39,000, 20,000, 18,000, 17,000, and 14,000. Protein isolate and DWGF showed very similar SDS-PAGE patterns. Except for prola- mine and glutelin fractions without detectable calorimetric response, the globulin fraction possessed the highest thermal stability (Td = 83.80°C, ΔH =1.36 J/g ), followed by protein isolate (Td = 80.05°C, ΔH = 0.76 J/g), while the albumin fraction was lowest (Td = 69.72°C, ΔH = 0.53 J/g). The findings on defatted wheat germ proteins are important for their potential application as functional food ingredients.",
        "keywords": [
            "differential scanning calorimetry",
            "amino acid",
            "thermal stability"
        ],
        "authors": [
            {
                "name": "Ke-Xue Zhu",
                "org": ""
            },
            {
                "name": "Hui-Ming Zhou",
                "org": ""
            },
            {
                "name": "Hai-Feng Qian",
                "org": "School of Food|Science and Technology|Yangtze University"
            }
        ],
        "venue": "Cereal Chemistry",
        "year": 2006
    },
    "uSXWltXX": {
        "id": "uSXWltXX",
        "title": "Adverse effects of levofloxacin and oxytetracycline on aquatic microbial communities.",
        "abstract": "The widespread use of levofloxacin (LEV) and oxytetracycline (OTC) in hospitals and farms inevitably contributes to water pollution through waste disposal processes, municipal wastewater treatment, and manure application to farmlands, which adversely affects aquatic microorganisms. Here, we evaluated the toxicity of LEV and OTC to cyanobacteria and eukaryotic algae monocultures and freshwater microcosms. Three test cyanobacteria were inhibited by both LEV and OTC at all examined concentrations. The growth of the eukaryotic organisms C. vulgaris and Monoraphidium sp. was only inhibited by high concentrations of OTC ranging from 1000 to 10,000 μg/L; however, they were less sensitive to LEV and OTC than cyanobacteria. In the aquatic microcosms, 5 μg/L of LEV and OTC did not affect the alpha diversity of prokaryotic and eukaryotic communities or the composition of the eukaryotic microbial communities after 14 d of exposure. However, this concentration of LEV and OTC significantly changed the prokaryotic microbial community structure at the genus level, and different antibiotics affected the prokaryotic microbial community differently, suggesting that different antibiotics affect prokaryotes through different molecular mechanisms, thereby leading to differences in prokaryotic microbial growth patterns. Moreover, the changes in the prokaryotic microbial community composition suggested that low antibiotic concentrations in water could disturb prokaryotic microbial communities and cause ecological risks.",
        "keywords": [
            "Algae",
            "Antibiotics",
            "Ecotoxicity",
            "Microcosm experiment"
        ],
        "authors": [
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Lan Feng",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Jinfeng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2020
    },
    "3dXRaHNn": {
        "id": "3dXRaHNn",
        "title": "Fast Poisson solvers for thermal analysis",
        "abstract": "Accurate and efficient thermal analysis for a VLSI chip is crucial, both for sign-off reliability verification and for design-time circuit optimization. To determine an accurate temperature profile, it is important to simulate a die together with its thermal mounts: this requires solving Poisson's equation on a non-rectangular 3D domain. This paper presents a class of eigendecomposition-based fast Poisson solvers (FPS) for chip-level thermal analysis. We start with a solver that solves a rectangular 3D domain with mixed boundary conditions in O(NlogN) time, where N is the dimension of the finite-difference matrix. Then we reveal, for the first time in the literature, a strong relation between fast Poisson solvers and Green-function-based methods. Finally, we propose an FPS method that leverages the preconditioned conjugate gradient method to solve non-rectangular 3D domains efficiently. We demonstrate that this approach solves a system of dimension 5.33e6 in only 11 Conjugate Gradient iterations, with a runtime of 171 seconds, a 6X speedup over the popular ICCG solver.\n\n",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "IBM T. J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota, Minneapolis, MN"
            }
        ],
        "venue": "ICCAD '10: The International Conference on Computer-Aided Design\n\t\t      San Jose\n\t\t      California\n\t\t    November, 2010",
        "year": 2010
    },
    "lWXBhhis": {
        "id": "lWXBhhis",
        "title": "Anti-diabetic activity of Vaccinium bracteatum Thunb. leaves' polysaccharide in STZ-induced diabetic mice.",
        "abstract": "Vaccinium bracteatum Thunb. (VBT) is a traditional Chinese herbal medicine. The anti-diabetic activity of VBT leaves' polysaccharide (VBTLP) is studied in this paper. The results indicated VBTLP had a dose-dependent decrease on the blood glucose (BG) level, and the time effect of VBTLP on BG level was also significant. The insulin level of high dose group (HDG) was significantly higher (p<0.05) than that of model control (MC) group. Compared to MC, HDG and lose dose group (LDG) had significantly lower (p<0.05) TC and LDL-C levels, however, TG and HDL-C levels are similar. Compared to non-diabetic control (NC), HDG and LDG had similar plasma lipid levels except for higher LDL-C level. Although body weights of LDG and HDG were significant lower (p<0.05) than that of NC from week 2 to week 6, they were similar to that of PC. The results indicate VBTLP possesses a potential hypoglycemic effect in streptozotocin-induced diabetic mice.",
        "keywords": [
            "vaccinium bracteatum thunb",
            "polysaccharides",
            "anti-diabetic activity"
        ],
        "authors": [
            {
                "name": "Li Wang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Ying Zhang",
                "org": "National Research Institute for Family Planning, Beijing(National Research Institute for Family Planning,Natl. Res. Inst. for Family Planning),Beijing,China"
            },
            {
                "name": "Maochao Xu",
                "org": "Illinois State University(Illinois State University),Chicago,United States"
            },
            {
                "name": "Yingyao Wang",
                "org": "Academy of State Administration of Grain(Academy of State Administration of Grain),Beijing,China"
            },
            {
                "name": "Sujiao Cheng",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Alex Liebrecht",
                "org": "Illinois State University(Illinois State University),Chicago,United States"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Xiguang Qi",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2013
    },
    "HDHNZwsC": {
        "id": "HDHNZwsC",
        "title": "Enzymatic hydrolysis of wheat gluten by proteases and properties of the resulting hydrolysates",
        "abstract": "The insolubility of gluten in aqueous solutions is one of the major limitations for its more extensive use in food processing. Wheat gluten was enzymatically hydrolyzed by several commercially available proteases (Alcalase 2.4L, PTN 6.0S, Pepsin, Pancreatin, Neutrase and Protamex™) with protein recovery of 81.3%, 42.5%, 53.3%, 61.6%, 46.3% and 43.8%, respectively. The hydrolytic efficiency of these proteases on wheat gluten was also compared. Alcalase served best for the preparation of wheat gluten hydrolysates with the maximum degree of hydrolysis (DH) 15.8%. Subsequently, the solubility of wheat gluten hydrolysates (WGHs) obtained with those enzymes was comparably evaluated. The products had excellent solubility (>60%) over a pH range of 2–12. The molecular weight distribution of WGHs was further determined by SDS-PAGE and size exclusion chromatography on Sephadex G-15. The results showed that with the increasing of DH values, there occurred a large amount of smaller polypeptides.",
        "keywords": [
            "wheat gluten",
            "solubility",
            "enzymatic hydrolysis",
            "sds-page",
            "enzyme",
            "maximum degree",
            "aqueous solution",
            "food processing",
            "size exclusion chromatography",
            "molecular weight distribution",
            "sds page"
        ],
        "authors": [
            {
                "name": "Xiangzhen Kong",
                "org": "Key Laboratory of Food Science and Safety, Ministry of Education, Southern Yangtze University, 170 Huihe Road, Wuxi, 214036 Jiangsu Province, PR China"
            },
            {
                "name": "Huiming Zhou",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology, Southern Yangtze University, 170 Huihe Road, Wuxi, 214036 Jiangsu Province, PR China"
            }
        ],
        "venue": "Food Chemistry",
        "year": 2007
    },
    "c28XDqCY": {
        "id": "c28XDqCY",
        "title": "Incubation Push or Business Pull? Investigating the Geography of U.S. Business Incubators",
        "abstract": "",
        "keywords": [
            "factor analysis",
            "entrepreneurship",
            "logistic regression",
            "geography"
        ],
        "authors": [
            {
                "name": "haifeng qian",
                "org": "cleveland state university"
            },
            {
                "name": "kingsley e haynes",
                "org": "george mason university"
            },
            {
                "name": "james d riggle",
                "org": "george mason university"
            }
        ],
        "venue": "Economic Development Quarterly",
        "year": 2011
    },
    "NMVey8Dw": {
        "id": "NMVey8Dw",
        "title": "Investigation of rhizospheric microbial communities in wheat, barley and two rice varieties at the seedling stage.",
        "abstract": "The plant rhizosphere microbiota plays multiple roles in plant growth. We investigated the taxonomic and functional variations in the rhizosphere microbial community, examining both prokaryotes and eukaryotes, of four crops at the seedling stage: wheat, barley and two rice varieties (indica and japonica) seeded in paddy soil. The diversity of rhizosphere communities in these four species were determined. Results showed that wheat and barley had much stronger selection effects than rice for the rhizosphere microbial community. Functional metagenomic profiling indicated that a series of sequences related to glycan, limonene and pinene degradation pathways, as well as some relatively rare functions related to N or S metabolism, were enriched in the rhizosphere soil. We conclude that the four tested crops induced the formation of microbial community with specific features which may influence the plant growth, but the stochastic processes also appreciably influenced the functional selection.",
        "keywords": "",
        "authors": [
            {
                "name": "Tao Lu",
                "org": ""
            },
            {
                "name": "Mingjing Ke",
                "org": ""
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300 RA Leiden, Netherlands"
            },
            {
                "name": "Youchao Zhu",
                "org": ""
            },
            {
                "name": "Meng Zhang",
                "org": ""
            },
            {
                "name": "Liwei Sun",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2018
    },
    "qHitmIB8": {
        "id": "qHitmIB8",
        "title": "Robust password changing and DoS resilience for human-centric password authentication: Robust password changing and DoS resilience",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiangxue li",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yu yu",
                "org": ""
            },
            {
                "name": "jian weng",
                "org": ""
            },
            {
                "name": "ziping wang",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2013
    },
    "5CykfUWe": {
        "id": "5CykfUWe",
        "title": "Color Image Cryptography Using Multiple One-Dimensional Chaotic Maps and OCML",
        "abstract": "In this paper, a stream color image cryptography has been proposed based on spatiotemporal chaos system. One-way coupled map lattices (OCML) are used to generate pseudorandom sequences and then encrypt image pixels one by one. By iterating randomly chosen chaotic maps from a set of chaotic maps for certain times, the generated pseudorandom sequences obtain high initial-value sensitivity and good randomness. The initial conditions of chaotic maps and parameters of the algorithm are generated by a 128-bit external key. Simulation results show that the proposed scheme is efficient and useful for the security of communication system.",
        "keywords": [
            "pseudorandom sequence",
            "good randomness",
            "multiple one-dimensional chaotic maps",
            "communication system",
            "chaotic map",
            "stream color image cryptography",
            "proposed scheme",
            "certain time",
            "128-bit external key",
            "encrypt image",
            "color image cryptography",
            "spatiotemporal chaos system",
            "cryptography",
            "coupled map lattice",
            "pixel",
            "lattices",
            "color",
            "initial condition",
            "correlation",
            "color image",
            "image resolution"
        ],
        "authors": [
            {
                "name": "Jun He",
                "org": ""
            },
            {
                "name": "Jun Zheng",
                "org": ""
            },
            {
                "name": "Zhi-bin Li",
                "org": ""
            },
            {
                "name": "Hai-feng Qian",
                "org": ""
            }
        ],
        "venue": "IEEC '09 Proceedings of the 2009 International Symposium on Information Engineering and Electronic Commerce",
        "year": 2009
    },
    "xF0R7skQ": {
        "id": "xF0R7skQ",
        "title": "EFFECTS OF DIFFERENT ADDITIVES ON RICE CAKE TEXTURE AND CAKE STALING: RICE CAKE TEXTURE AND CAKE STALING",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "YING JI",
                "org": ""
            },
            {
                "name": "KEXUE ZHU",
                "org": ""
            },
            {
                "name": "ZHI-CHENG CHEN",
                "org": ""
            },
            {
                "name": "HUIMING ZHOU",
                "org": ""
            },
            {
                "name": "JIAXI MA",
                "org": ""
            },
            {
                "name": "HAIFENG QIAN",
                "org": ""
            }
        ],
        "venue": "Journal of Texture Studies",
        "year": 2010
    },
    "2Ugk5F3y": {
        "id": "2Ugk5F3y",
        "title": "Cryptography based on Spatiotemporal Chaos System and Multiple Maps",
        "abstract": "",
        "keywords": [
            "chaos",
            "color image cipher",
            "multiple chaotic maps",
            "ocml"
        ],
        "authors": [
            {
                "name": "Jun He",
                "org": ""
            },
            {
                "name": "Zhi-bin Li",
                "org": ""
            },
            {
                "name": "Hai-feng Qian",
                "org": ""
            }
        ],
        "venue": "JSW",
        "year": 2010
    },
    "37qUGJWp": {
        "id": "37qUGJWp",
        "title": "Geographical dimensions of federal investment in small business development",
        "abstract": "",
        "keywords": [
            "economics and finance",
            "geography"
        ],
        "authors": [
            {
                "name": "kingsley e haynes",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "sidney c turner",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "JVFxhFol": {
        "id": "JVFxhFol",
        "title": "Geniposide improves glucose homeostasis via regulating FoxO1/PDK4 in skeletal muscle.",
        "abstract": "It is well known that imbalance state of glucose metabolism triggers many metabolic diseases and glucose uptake in skeletal muscle accounts for 90% of body weight. Geniposide is one of the major natural bioactive constituents of gardenia fruit, and the regulation of geniposide on glucose metabolism in skeletal muscle has not been investigated yet. Here, based on microarray analysis, we discovered that geinposide decreased PDK4 expression in skeletal muscle of mice, and we subsequently found that geniposide inhibited the expressions of FoxO1, PDK4, P-PDH in vitro and in vivo. Moreover, geniposide promoted a switch of slow-to-fast myofiber type and glucose utilization, suggesting that geniposide improved glucose homeostasis. In addition, mechanistic studies revealed that geniposide played above roles by regulating FoxO1/PDK4, which controlled fuel selection via PDH. Meanwhile, effects of geniposide mentioned above could be reversed by FoxO1 overexpression. Together, these results establish that geniposide confers controls on fuel usage and glucose homeostasis through FoxO1/PDK4 in skeletal muscle.",
        "keywords": "",
        "authors": [
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Haiou Pan",
                "org": ""
            },
            {
                "name": "Xuetong Zhang",
                "org": ""
            },
            {
                "name": "Hui Wang",
                "org": ""
            },
            {
                "name": "Shengnan Liu",
                "org": ""
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            },
            {
                "name": "Hao Ying",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2019
    },
    "tsxyZQJM": {
        "id": "tsxyZQJM",
        "title": "Antioxidant and Free Radical Scavenging Potential of Peanut Meal Hydrolysate Prepared Using Bacillus Subtilis Fermentation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "xiaona guo",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "youwei zhang",
                "org": ""
            },
            {
                "name": "xia lu",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            }
        ],
        "venue": "International Journal of Food Properties",
        "year": 2013
    },
    "XyUWSgBP": {
        "id": "XyUWSgBP",
        "title": "Two novel herbicide candidates affect Arabidopsis thaliana growth by inhibiting nitrogen and phosphate absorption.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "chongchong sun",
                "org": ""
            },
            {
                "name": "yujian jin",
                "org": ""
            },
            {
                "name": "haifeng he",
                "org": ""
            },
            {
                "name": "wei wang",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "Pesticide Biochemistry and Physiology",
        "year": 2015
    },
    "OzZ7O18Z": {
        "id": "OzZ7O18Z",
        "title": "Copper toxicity to : a survey of the sensitivity of various toxicity endpoints at the physiological, biochemical, molecular and structural levels",
        "abstract": "Copper (Cu) is one of the most toxic metals in phytoplankton but the toxicity mechanisms of this metal are still not fully understood. This study examines the toxicity targets of Cu in the modeled marine diatom, , at the physiological (cell division, DNA cell cycle), biochemical [pigments synthesis, reactive oxygen species (ROS) and malondialdehyde (MDA)], structural (subcellular observation by flow cytometry) and molecular (transcription of several metalloprotein genes) level. Cu toxicity was detectable at all these levels after 48 h of exposure to ≥20 μM total initial added Cu. The order of sensitivity of all the studied Cu toxicity endpoints was: G2/M phase > MDA > metalloproteins RNA of the photosynthetic electron transport chain (ETC) > metalloproteins RNA of the respiratory chains > G0/G1 phase > pigments ≈ S phase > propidium iodide > estimated cell yield > ROS. The relatively sensitive decrease of the transcription of metalloproteins RNA of the ETC in response to Cu exposure, if associated to an effective decrease in the expression of the proteins composing the ETC, may help to initially mitigate the ROS-mediated toxic effects of Cu in . . However, this cellular response to Cu was only transitory and the transcription of virtually all genes involved in redox electron transfer chains was up-regulated within an interval of 2 days. This study brings new insights into the cellular mechanisms of Cu toxicity by documenting the sensitivity and kinetics of multiple Cu-cellular targets in one marine alga.",
        "keywords": [
            "Phaeodactylum tricornutum",
            "Copper toxicity",
            "Electron transfer chains",
            "Gene transcript"
        ],
        "authors": [
            {
                "name": "Yong Wei",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of ChinaCollege of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Na Zhu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit,Université Laval,Quebec,Canada"
            },
            {
                "name": "Jiaying Wang",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "BioMetals",
        "year": 2014
    },
    "nhTEi5kw": {
        "id": "nhTEi5kw",
        "title": "Developmental neurotoxicity of organophosphate flame retardants in early life stages of Japanese medaka (Oryzias latipes).",
        "abstract": "Because brominated flame retardants are being banned or phased out worldwide, organophosphate flame retardants have been used as alternatives on a large scale and have thus become ubiquitous environmental contaminants; this raises great concerns about their environmental health risk and toxicity. Considering that previous research has identified the nervous system as a sensitive target, Japanese medaka were used as an aquatic organism model to evaluate the developmental neurotoxicity of 4 organophosphate flame retardants: triphenyl phosphate, tri-n-butyl phosphate, tris(2-butoxyethyl) phosphate, and tris(2-chloroethyl) phosphate (TCEP). The embryo toxicity test showed that organophosphate flame retardant exposure could decrease hatchability, delay time to hatching, increase the occurrence of malformations, reduce body length, and slow heart rate. Regarding locomotor behavior, exposure to the tested organophosphate flame retardants (except TCEP) for 96 h resulted in hypoactivity for medaka larvae in both the free-swimming and the dark-to-light photoperiod stimulation test. Changes of acetylcholinesterase activity and transcriptional responses of genes related to the nervous system likely provide a reasonable explanation for the neurobehavioral disruption. Overall, the present study clearly demonstrates the developmental neurotoxicity of various organophosphate flame retardants with very different potency and contribute to the determination of which organophosphate flame retardants are appropriate substitutes, as well as the consideration of whether regulations are reasonable and required. Environ Toxicol Chem 2016;35:2931-2940. © 2016 SETAC.",
        "keywords": [
            "Behavioral toxicology",
            "Embryo toxicity test",
            "Gene transcriptional analysis",
            "Neurotoxicity",
            "Organophosphate"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Hana Tan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Tao Peng",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Sisi Wang",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Wenbin Xu",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            }
        ],
        "venue": "Environmental toxicology and chemistry",
        "year": 2016
    },
    "pI9iZE8e": {
        "id": "pI9iZE8e",
        "title": "Influence of deep-frying using various commercial oils on acrylamide formation in French fries.",
        "abstract": "This study investigated the effect of different types of commercial oils (rice bran oil, shortening oil, high-oleic rapeseed oil, low-erucic acid rapeseed oil, blend oil A and blend oil B) and frying cycles on acrylamide formation during the preparation of French fries by deep-frying. Frying was carried out in intermittent mode (two batches each for 12 min without any time lag) and repeated for 600 frying cycles. Results indicated that the French fries that were fried in oils having lower heat transfer coefficients contained lower acrylamide concentrations (913 µg kg(-1)), whereas those fried with oils having higher heat transfer coefficients contained higher acrylamide concentrations (1219 µg kg(-1)). Unlike the peroxide value, acrylamide levels in French fries did not change significantly with an increase in the number of frying cycles when tested for 600 frying cycles for every type of oil. This study clearly indicates that the contribution of frying oils to the formation of acrylamide should not be neglected due to their different heat transfer coefficients. On the other hand, continuous use of frying oil does not lead to a higher acrylamide concentration in French fries.",
        "keywords": [
            "acrylamide",
            "commercial oils",
            "heat transfer coefficient",
            "peroxide value"
        ],
        "authors": [
            {
                "name": "Hao Zhang",
                "org": "a State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology , Jiangnan University , Wuxi , China."
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Lilin Cheng",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment",
        "year": 2015
    },
    "ZtqmaaaP": {
        "id": "ZtqmaaaP",
        "title": "Metabolomics approach reveals discriminatory metabolites associating with the blue pigments from Vaccinium bracteatum thunb. Leaves at different growth stages",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Mingcong Fan",
                "org": ""
            },
            {
                "name": "Weijia Lian",
                "org": ""
            },
            {
                "name": "Tingting Li",
                "org": ""
            },
            {
                "name": "Yihui Fan",
                "org": ""
            },
            {
                "name": "Zhiming Rao",
                "org": ""
            },
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Gangcheng Wu",
                "org": ""
            },
            {
                "name": "Xiguang Qi",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            }
        ],
        "venue": "Industrial Crops and Products",
        "year": 2020
    },
    "YvdsNZmL": {
        "id": "YvdsNZmL",
        "title": "Stability assessment of crocetin and crocetin derivatives in Gardenia yellow pigment and Gardenia fruit pomace in presence of different cooking methods.",
        "abstract": "Gardenia fruit pomace (GFP) is a byproduct during the Gardenia oil production and rich in Gardenia yellow pigment (GY) in which the major functional components are crocetin and crocetin derivatives (CDs). The application of GFP was still limited. In this research, the stabilities of CDs during thermal and lighting treatment were studied, food systems with GY or GFP were simulated to evaluate the effects of cooking methods on CDs. Seven CDs were identified and determined in GY and GFP by UPLC-QToF-MS and HPLC. The stability results showed that CDs were sensitive to heat and light, the great loss of total CDs and detachment of aglycon were observed during thermal treatment. Light-driven degradation reactions of CDs fitted the first-order model. Different cooking methods (boiling, baking, steaming) had distinct impacts on the CDs contents in the simulated food system with GY and GFP, steaming should be an appropriate method for cooking.",
        "keywords": [
            "Crocetin derivatives",
            "Different cooking methods",
            "Gardenia fruit pomace (GFP)",
            "Gardenia yellow pigment (GY)",
            "Stability"
        ],
        "authors": [
            {
                "name": "Na Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Mingcong Fan",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "aKT0W4tz": {
        "id": "aKT0W4tz",
        "title": "Comparison of the toxicity of silver nanoparticles and silver ions on the growth of terrestrial plant model Arabidopsis thaliana.",
        "abstract": "Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials, but the mechanism of AgNP toxicity in terrestrial plants is still unclear. We compared the toxic effects of AgNPs and Ag+ on Arabidopsis thaliana at the physiological, ultrastructural and molecular levels. AgNPs did not affect seed germination; however, they showed stronger inhibitory effect on root elongation than Ag+. The results of transmission electron microscopy and metal content analysis showed that AgNPs could be accumulated in leaves. These absorbed AgNPs disrupted the thylakoid membrane structure and decreased chlorophyll content, which can inhibit plant growth. By comparison, a small amount of Ag+ was absorbed by seedlings, and it did not pronouncedly affect chloroplast structure and other metal ion absorption as AgNPs did. Compared with Ag+, AgNPs could alter the transcription of antioxidant and aquaporin genes, indicating that AgNPs changed the balance between the oxidant and antioxidant systems, and also affected the homeostasis of water and other small molecules within the plant body. All the data from physiological, ultrastructural and molecular levels suggest that AgNPs were more toxic than Ag+.",
        "keywords": [
            "arabidopsis thaliana",
            "silver nanoparticles",
            "gene transcript",
            "antioxidant enzyme",
            "ag+",
            "aquaporins",
            "ag"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Xiaofeng Peng",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Xiao Han",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Jie Ren",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China."
            }
        ],
        "venue": "Journal of environmental sciences (China)",
        "year": 2013
    },
    "nVZXR80K": {
        "id": "nVZXR80K",
        "title": "The fungicide azoxystrobin promotes freshwater cyanobacterial dominance through altering competition.",
        "abstract": "Sharp increases in food production worldwide are attributable to agricultural intensification aided by heavy use of agrochemicals. This massive use of pesticides and fertilizers in combination with global climate change has led to collateral damage in freshwater systems, notably an increase in the frequency of harmful cyanobacterial blooms (HCBs). The precise mechanisms and magnitude of effects that pesticides exert on HCBs formation and proliferation have received little research attention and are poorly constrained. We found that azoxystrobin (AZ), a common strobilurin fungicide, can favor cyanobacterial growth through growth inhibition of eukaryotic competitors (Chlorophyta) and possibly by inhibiting cyanobacterial parasites (fungi) as well as pathogenic bacteria and viruses. Meta-transcriptomic analyses identified AZ-responsive genes and biochemical pathways in eukaryotic plankton and bacteria, potentially explaining the microbial effects of AZ. Our study provides novel mechanistic insights into the intertwined effects of a fungicide and eutrophication on microbial planktonic communities and cyanobacterial blooms in a eutrophic freshwater ecosystem. This knowledge may prove useful in mitigating cyanobacteria blooms resulting from agricultural intensification.",
        "keywords": [
            "Fungicide",
            " Eutrophication",
            " Algal bloom",
            " Meta-transcriptomics",
            " Indirect effects"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada"
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Jun Yang",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, People’s Republic of China"
            },
            {
                "name": "Hans W Paerl",
                "org": "Institute of Marine Sciences, University of North Carolina at Chapel Hill, Morehead City, USA"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Yong-Guan Zhu",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, People’s Republic of China"
            }
        ],
        "venue": "Microbiome",
        "year": 2019
    },
    "8igsLPU6": {
        "id": "8igsLPU6",
        "title": "Temperature-Aware Placement for SOCs High and uneven temperatures can be avoided when appropriate thermal modeling and simulation are incorporated in placement algorithms for components and interconnections in systems-on-chip",
        "abstract": "Dramatic rises in the power consumption and integration density of contemporary systems-on-chip (SoCs) have led to the need for careful attention to chip-level thermal integrity. High temperatures or uneven temperature distribu- tions may result not only in reliability issues, but also timing failures, due to the temperature-dependent nature of chip time-to-failure and delay, respectively. To resolve these issues, high-quality, accurate thermal modeling and analysis, and thermally oriented placement optimizations, are essential prior to tapeout. This paper first presents an overview of thermal modeling and simulation methods, such as finite-difference time domain, finite element, model reduction, random walk, and Green-function based algorithms, that are appropriate for use in placement algorithms. Next, two-dimensional and three- dimensional thermal-aware placement algorithms such as matrix-synthesis, simulated annealing, partition-driven, and force directed are presented. Finally, future trends and challenges are described.",
        "keywords": [
            "placement",
            "thermal analysis",
            "physical design",
            "thermal simulation",
            "system on chip",
            "random walk",
            "chip",
            "simulated annealing",
            "three dimensional",
            "green function",
            "finite element model",
            "finite difference time domain"
        ],
        "authors": [
            {
                "name": "Jeng-Liang Tsai",
                "org": ""
            },
            {
                "name": "Charlie Chung-Ping Chen",
                "org": ""
            },
            {
                "name": "Guoqiang Chen",
                "org": ""
            },
            {
                "name": "Brent Goplen",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yong Zhan",
                "org": ""
            },
            {
                "name": "Martin D. F. Wong",
                "org": ""
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "H10UXbFb": {
        "id": "H10UXbFb",
        "title": "Early radiometric calibration performances of GOES-16 advanced baseline imager.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Boryana Efremova",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Bob Iacovazzi",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems XXII",
        "year": 2017
    },
    "rlSCezs9": {
        "id": "rlSCezs9",
        "title": "Screening of chemicals with anti-estrogenic activity using in vitro and in vivo vitellogenin induction responses in zebrafish (Danio rerio).",
        "abstract": "Growing concern over possible adverse effects of endocrine-disrupting chemicals (EDCs) has driven the development of associated screening methods. The use of the vitellogenin (VTG) induction response in cultured teleost hepatocytes has been suggested as an in vitro screening assay for EDCs. However, current data do not sufficiently support this assay in the routine screening of chemicals. This study established and validated the use of primary cultured hepatocytes from zebrafish to screen chemicals for anti-estrogenic activities. Here we measured the transcript levels of selected hepatic estrogen-response genes, including vtg1, vtg2 and eralpha. Two model anti-estrogens, letrozole (LET), an aromatase inhibitor, and tamoxifen (TAM), a competitive estrogen receptor, were selected as representative chemicals. Additionally, comparisons between in vitro and in vivo assays were performed. As expected, there were concentration-dependent decreases for all three genes in the liver of female zebrafish exposed to LET in vivo for 72h. Similar responses were observed in males. As for in vitro testing, no discernable alterations in the gene transcripts were found in hepatocytes from males or females. In the case of TAM, exposure for 72h caused transcriptional reduction of hepatic estrogen-response genes in females in vivo and in vitro. In males, low concentrations of TAM resulted in increased expression of genes, while the expression decreased slightly at higher concentrations. Since these observations were in agreement with the pharmaceutical properties of two tested chemicals, the primary hepatocyte culture could be a promising tool for screening suspected EDCs.",
        "keywords": [
            "anti-estrogen",
            "mtt assay",
            "primary hepatocyte culture",
            "real-time quantitative pcr"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Liling Wen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Xiaolu Shao",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Chemosphere",
        "year": 2010
    },
    "s5sgPsIH": {
        "id": "s5sgPsIH",
        "title": "Early-stage power grid analysis for uncertain working modes",
        "abstract": "High-performance integrated circuits are now reaching the 100-plus watt regime, and power delivery and power grid signal integrity have become critical. Analyzing the performance of the power delivery system requires knowledge of the current drawn by the functional blocks that comprise a typical hierarchical design. However, current designs are of such complexity that it is difficult for a designer to determine what a realistic worst-case switching pattern for the various blocks would be in order to maximize noise at a specific location. This paper uses information about the power dissipation of a chip to derive an upper bound on the worst-case voltage drop at an early stage of design. An exact integer linear programming (ILP) method is first developed, followed by an effective heuristic to speed up the exact method. A circuit of 43 K nodes is analyzed within 70 s, and the worst-case scenarios found correlate well with the results from an ILP solver.",
        "keywords": [
            "ILP solver",
            "worst-case voltage drop",
            "exact integer linear programming",
            "power dissipation",
            "worst-case scenario",
            "Early-stage power grid analysis",
            "power delivery",
            "realistic worst-case switching pattern",
            "power grid signal integrity",
            "power delivery system",
            "uncertain working mode",
            "current design"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Dept. of Electr. & Comput. Eng., Univ. of Minnesota, Minneapolis, MN, USA"
            },
            {
                "name": "Sani R. Nassif",
                "org": "IBM Austin Research Labs, Austin, TX"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota, Minneapolis, MN"
            }
        ],
        "venue": "IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems",
        "year": 2006
    },
    "QXDb22qF": {
        "id": "QXDb22qF",
        "title": "Scalable and Soundness Verifiable Outsourcing Computation in Marine Mobile Computing.",
        "abstract": "Outsourcing computation with verifiability is a merging notion in cloud computing, which enables lightweight clients to outsource costly computation tasks to the cloud and efficiently check the correctness of the result in the end. This advanced notion is more important in marine mobile computing since the oceangoing vessels are usually constrained with less storage and computation resources. In such a scenario, vessels always firstly outsource data set and perform a function computing over them or at first outsource computing functions and input data set into them. However, vessels may choose which delegation computation type to outsource, which generally depends on the actual circumstances. Hence, we propose a scalable verifiable outsourcing computation protocol () in marine cloud computing at first and extract a single-mode version of it (), where both protocols allow anyone who holds verification tokens to efficiently verify the computed result returned from cloud. In this way, the introduced “scalable” property lets vessels adjust the protocol to cope with different delegation situations in practice. We additionally prove both and achieving selective soundness in the random oracle model and evaluate their performance in the end.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Lifei Wei",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Wireless Communications and Mobile Computing",
        "year": 2017
    },
    "7FaNbe4b": {
        "id": "7FaNbe4b",
        "title": "Certificateless Threshold Signature Schemes",
        "abstract": "\n We analyze the relationship and subtle difference between the notion of certificateless public key cryptography (CL-PKC) and\n identity-based schemes without a trusted private key generator (PKG), then propose a certificateless threshold signature scheme\n based on bilinear pairings. The proposed scheme is robust and existentially unforgeable against adaptive chosen message attacks\n under CDH assumption in the random oracle model.\n \n ",
        "keywords": [
            "existentially unforgeable",
            "cdh assumption",
            "identity-based scheme",
            "certificateless public key cryptography",
            "random oracle model",
            "proposed scheme",
            "certificateless threshold signature scheme",
            "message attack",
            "private key generator",
            "bilinear pairings",
            "public key cryptography"
        ],
        "authors": [
            {
                "name": "Licheng Wang",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200030 China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200030 China"
            },
            {
                "name": "Xiangxue Li",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200030 China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200030 China"
            }
        ],
        "venue": "Computational and Information Science",
        "year": 2005
    },
    "8Fq25UEA": {
        "id": "8Fq25UEA",
        "title": "Correction to l-Arabinose Inhibits Colitis by Modulating Gut Microbiota in Mice",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yan Li",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Haiou Pan",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Jin-xin Liu",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Tingting Li",
                "org": "Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Shengnan Liu",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Wenli Shi",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Chao Sun",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Mingcong Fan",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Lamei Xue",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Yu Wang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Chenzhipeng Nie",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            },
            {
                "name": "Hao Ying",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Li Wang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, China"
            }
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2020
    },
    "j4X4scSC": {
        "id": "j4X4scSC",
        "title": "Direct Construction of Signcryption Tag-KEM from Standard Assumptions in the Standard Model",
        "abstract": "The paper presents a direct construction of signcryption tag-KEM under the standard DBDH and CDH assumptions in the standard model, without using strongly unforgeable signature schemes as building blocks. We prove its confidentiality and unforgeability with respect to adversarially-chosen keys where the adversary is given more advantageous attack environment than existing models in the literature. The performance of our construction is comparable to existing signcryption tag-KEM schemes.",
        "keywords": [],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Jian Weng",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            }
        ],
        "venue": "ICICS",
        "year": 2013
    },
    "m6YVaacR": {
        "id": "m6YVaacR",
        "title": "Stereoselective Phytotoxicity of HCH Mediated by Photosynthetic and Antioxidant Defense Systems in Arabidopsis thaliana",
        "abstract": "",
        "keywords": [
            "photosynthesis",
            "physics",
            "biology",
            "risk assessment",
            "engineering",
            "medicine",
            "stereoisomerism",
            "plant leaves",
            "chemistry"
        ],
        "authors": [
            {
                "name": "cong zhou",
                "org": "zhejiang university of technology"
            },
            {
                "name": "quan zhang",
                "org": "zhejiang university of technology"
            },
            {
                "name": "haifeng qian",
                "org": "zhejiang university of technology"
            },
            {
                "name": "weiping liu",
                "org": "science college"
            },
            {
                "name": "meirong zhao",
                "org": "zhejiang university of technology"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2013
    },
    "OoeHXuy6": {
        "id": "OoeHXuy6",
        "title": "TEMPORARY REMOVAL: Effects of oxathiapiprolin on photosynthetic activity of Chlorella pyrenoidosa probed by chlorophyll fluorescence and thermoluminescence assays.",
        "abstract": "Oxathiapiprolin is the first member of the piperidinyl thiazole isoxazoline fungicides developed globally as DuPont™ Zorvec™ for the control of plant diseases caused by Oomycete pathogens. Although they have great application potential, ecotoxicological data, especially their non-target effects on photosynthesis of algae and higher plants are completely lacking. Effects of a novel oxathiapiprolin biocide on the photosynthesis of Chlorella pyrenoidosa were therefore investigated using chlorophyll a fluorescence and thermoluminescence techniques. Effects of the bioicide on photosynthetic electron transport and energy absorption and dissipation were concentration dependent. Inhibition of the electron donor side of PSII significantly increased as oxathiapiprolin concentration increased from 0 to 100 μM. The oxathiapiprolin treatment increased the effective antenna size per reaction center and the dissipated energy flux per reaction center. It damaged PSII reaction centers and blocked the electron transport flux, thus inhibiting photochemical activity in Chlorella pyrenoidosa. Exposure to oxathiapiprolin at concentrations up to 50 μM had little effect on QA− reoxidation kinetics on the electron acceptor side. Only a higher concentration (100 μM) of the oxathiapiprolin biocide exerted obvious inhibitory effects on QA− reoxidation. At 100 μM, electron transport beyond QA was drastically blocked, and more QA was reoxidized through S2(QAQB)− charge combination. As the concentration increased from 0 to 100 μM, the thermoluminescence C band decreased with increasing oxathiapiprolin concentration, whereas the intensity of the Q band increased which was associated with the decrease of B1 and B2 band intensity. This confirmed that the bioicide hindered electron transfer after QA and caused an increase of S2/S3QB− and TyrD+ QA− recombination. This study implies that when oxathiapiprolin biocides are applied to farmlands, they may pose a potential risk to algae and higher plants.",
        "keywords": "",
        "authors": [
            {
                "name": "Chudong Huang",
                "org": "College of Civil Engineering and Architecture, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Hang Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Daoyong Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Chengxia Tan",
                "org": "College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Yayun Pan",
                "org": "College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Shuzhi Wang",
                "org": "State Key Laboratory of Desert and Oasis Ecology, Xinjiang, Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Youmin Ying",
                "org": "College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China."
            },
            {
                "name": "Geoffrey Michael Gadd",
                "org": "Geomicrobiology Group, School of Life Sciences, University of Dundee, Dundee, DD15EH, Scotland, UK."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, China."
            }
        ],
        "venue": "Pesticide biochemistry and physiology",
        "year": 2017
    },
    "jeV1f8iY": {
        "id": "jeV1f8iY",
        "title": "Effects of the herbicide Imazethapyr on photosynthesis in PGR5- and NDH-deficient Arabidopsis thaliana at the biochemical, transcriptomic, and proteomic levels.",
        "abstract": "Photosynthesis is a very important metabolic pathway for plant growth and crop yield. This report investigated the effect of the herbicide imazethapyr on photosynthesis in the Arabidopsis thaliana pnsB3 mutant (a defect in the NDH pathway) and pgr5 mutant (a defect in the PGR5 pathway) to determine which cyclic electron transport chain (CET) of the NDH and PGR5 pathways is more important for protecting the photosynthetic system under herbicide stress. The results showed that 20 μg/L imazethapyr markedly inhibited the growth of the three ecotypes of A. thaliana and produced more anthocyanins and reactive oxygen species (ROS), particularly in the pgr5 mutant. The chlorophyll fluorescence results showed that PSII was severely damaged in the pgr5 mutant. Additionally, the CET was significantly stimulated to protect the photosynthetic system from light damage in Wt and the pnsB3 mutant but not the pgr5 mutant. The real-time PCR analysis indicated that imazethapyr treatment considerably decreased the transcript levels of most photosynthesis-related genes in the three treated groups. Several genes in the PGR5 pathway were significantly induced in the pnsB3 mutant, but no genes in the NDH pathway were induced in the pgr5 mutant. The gene transcription analysis showed that the pgr5 mutant cannot compensate for the deficit in the PGR5 pathway by stimulating the NDH pathway, whereas the pnsB3 mutant can compensate for the deficit in the CET cycle by regulating the PGR5 pathway. The iTRAQ analyses also showed that the photosynthesis system, glycolysis and TCA cycle suffered the most severe damage in the pgr5 mutant. All of these results showed that the PGR5 pathway is more critical for electron transfer around PSI than the NDH pathway to resist herbicide stress.",
        "keywords": "",
        "authors": [
            {
                "name": "Chongchong Sun",
                "org": ""
            },
            {
                "name": "Si Chen",
                "org": ""
            },
            {
                "name": "Yujian Jin",
                "org": ""
            },
            {
                "name": "Hao Song",
                "org": ""
            },
            {
                "name": "Songlin Ruan",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            },
            {
                "name": "Muhammad Asad Ullah Asad",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2016
    },
    "R1OprPgx": {
        "id": "R1OprPgx",
        "title": "Inhibitory effects of paraquat on photosynthesis and the response to oxidative stress in  ",
        "abstract": "This study investigated the effects of paraquat, a widely used herbicide, on the aquatic unicellular alga  through short-term toxicity tests at the physiological and gene transcriptional levels. Exposure to 0.5 μM paraquat increased the activities of the antioxidant enzymes superoxide dismutase, peroxidase, and catalase to levels 4.93, 3.19, and 3.09 times higher, respectively, than those of the control. Furthermore, exposure to 0.75 μM paraquat increased the activities of these antioxidant enzymes to even higher levels. The decrease in chlorophyll content and the increases in reactive oxygen species (ROS) and malondialdehyde content following exposure to paraquat suggest that the alga was severely damaged and cell growth was greatly inhibited. Real-time PCR showed that paraquat reduced the transcript abundance of B and L to 7.09 and 29.83% of the control, respectively. Our results demonstrate that paraquat inhibited electron transport and CO assimilation, and also triggered the synthesis of ROS that disrupt cellular structure and inhibit cell growth.",
        "keywords": [
            "Chlorella vulgaris",
            "Paraquat",
            "Real-time PCR",
            "Gene transcript"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            },
            {
                "name": "Wei Chen",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            },
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,China"
            }
        ],
        "venue": "Ecotoxicology",
        "year": 2009
    },
    "eD9gkhZx": {
        "id": "eD9gkhZx",
        "title": "Provably secure RSA‐type signature based on conic curve",
        "abstract": "In electronic communication and wireless communication, message authentication should\n         be necessary. However, traditional method message authentication code (MAC) employs\n         a symmetric cryptographical technique and it needs to keep a shared private key between\n         two parties. For convenience, people now begins to use public key techniques to provide\n         message authentication. In wireless communication, we shall save more space for message\n         itself because of the limited resources. Therefore, we believe that our proposed digital\n         signature scheme will be more fitful for this kind of communication due to the following\n         merits: (1) in addition to inheriting the merits of RSA signature such as high verification\n         efficiency, the proposed scheme also shows its advantage over RSA by resisting low\n         public key exponent attack; (2) comparing with 1024 bits RSA, our digital signature\n         scheme can sign 2048‐bit long message once, and generate a signature with 1025 bits\n         length which doubles the capacity of the 1024‐bit RSA signature; (3) the scheme is\n         provably secure and its security is tightly related to the hardness of conic‐based\n         (CB)‐RSA assumption. Copyright © 2008 John Wiley & Sons, Ltd.\n      ",
        "keywords": [
            "signature with message recovery",
            "mobile communication",
            "provable secure",
            "conic curve"
        ],
        "authors": [
            {
                "name": "Xiaolei Dong",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai\n               200240, P.R. China\n            "
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science, East China Normal University, Shanghai 200240, P.R.\n               China\n            "
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai\n               200240, P.R. China\n            "
            }
        ],
        "venue": "Wireless Communications and Mobile Computing",
        "year": 2009
    },
    "s3HKY1Nr": {
        "id": "s3HKY1Nr",
        "title": "Response of the terrestrial carbon cycle to the El Niño-Southern Oscillation",
        "abstract": "",
        "keywords": [
            "el nino southern oscillation",
            "leaf area index",
            "carbon cycle",
            "inverse modeling",
            "soil moisture",
            "global carbon cycle",
            "biogeochemical cycle"
        ],
        "authors": [
            {
                "name": "HAIFENG QIAN",
                "org": ""
            },
            {
                "name": "RENU JOSEPH",
                "org": ""
            },
            {
                "name": "NING ZENG",
                "org": ""
            }
        ],
        "venue": "Tellus Series B-chemical and Physical Meteorology",
        "year": 2008
    },
    "uEyK15si": {
        "id": "uEyK15si",
        "title": "Toxicity and enantiospecific differences of two β-blockers, propranolol and metoprolol, in the embryos and larvae of zebrafish ( Danio rerio ): Toxicity and Enantiospecific Differences of Two β-Blockers in Zebrafish",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yuanxiang jin",
                "org": ""
            },
            {
                "name": "rong jin",
                "org": ""
            },
            {
                "name": "zuhua peng",
                "org": ""
            },
            {
                "name": "lihua xin",
                "org": ""
            },
            {
                "name": "liwei sun",
                "org": ""
            }
        ],
        "venue": "Environmental Toxicology",
        "year": 2013
    },
    "MHUip3iW": {
        "id": "MHUip3iW",
        "title": "Evaluation of the Sensor Data Record from the nadir instruments of the Ozone Mapping Profiler Suite (OMPS): OMPS Nadir SDR Evaluation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "lawrence e flynn",
                "org": ""
            },
            {
                "name": "m z caponi",
                "org": ""
            },
            {
                "name": "daniel cumpton",
                "org": ""
            },
            {
                "name": "c owen",
                "org": ""
            },
            {
                "name": "wenhao li",
                "org": ""
            },
            {
                "name": "derek stuhmer",
                "org": ""
            },
            {
                "name": "m k rama varma raja",
                "org": ""
            },
            {
                "name": "wei yu",
                "org": ""
            },
            {
                "name": "eric beach",
                "org": ""
            },
            {
                "name": "trevor beck",
                "org": ""
            },
            {
                "name": "jianguo niu",
                "org": ""
            },
            {
                "name": "r buss",
                "org": ""
            },
            {
                "name": "bhaswar sen",
                "org": ""
            },
            {
                "name": "jian zeng",
                "org": ""
            },
            {
                "name": "michael grotenhuis",
                "org": ""
            },
            {
                "name": "glen jaross",
                "org": ""
            },
            {
                "name": "quanhua liu",
                "org": ""
            },
            {
                "name": "xiangqian wu",
                "org": ""
            },
            {
                "name": "chunhui pan",
                "org": ""
            },
            {
                "name": "s janz",
                "org": ""
            },
            {
                "name": "william johnsen",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "Journal of Geophysical Research",
        "year": 2014
    },
    "5OneT8Lv": {
        "id": "5OneT8Lv",
        "title": "A comparison of the effects of copper nanoparticles and copper sulfate on Phaeodactylum tricornutum physiology and transcription.",
        "abstract": "Copper nanoparticles (CuNPs) have been used in a broad range of applications. However, they are inevitably released into the marine environment, making it necessary to evaluate their potential effects on marine phytoplankton. In this study, the short-term (96h) effects of CuNPs and CuSO4 on Phacodactylum tricornutum growth, photosynthesis, reactive oxygen species production and transcription were assessed. It was found that high concentrations (40μM) of CuNPs and CuSO4 significantly inhibited the growth, photosynthesis and induced oxidative stress of P. tricornutum, while lower concentrations caused a hormetic response as indicated by a slight stimulation in algal growth. The high percentage of dissolved Cu (78-100%) in culture medium suggested that the dissolved Cu was the main driver of toxicity during CuNPs treatment. The algal cells upregulated electron transport chain-related genes to produce more energy and restore photosynthesis after 96h of treatment with CuNPs and CuSO4. This study delineates the cellular mechanism behind the toxicity of CuNPs and CuSO4 on marine diatoms.",
        "keywords": [
            "Copper nanoparticles",
            "Gene transcription",
            "Oxidative stress",
            "Phaeodactylum tricornutum"
        ],
        "authors": [
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            }
        ],
        "venue": "Environmental toxicology and pharmacology",
        "year": 2017
    },
    "nlk96yns": {
        "id": "nlk96yns",
        "title": "L-Arabinose inhibits colitis by modulating gut microbiota in mice.",
        "abstract": "L-Arabinose is a monosaccharide extracted from plants or fibers, which is known to have a variety of functional properties. In this study, we aim to investigate whether L-Arabinose could inhibit colitis by modulating gut microbiota. L-Arabinose was administrated in mice daily in a DSS-induced colitis model. The histological analysis, disease index and the expression of inflammatory genes were measured. 16S-rRNA sequence analysis was performed to investigate gut microbiota. Intriguingly, we found that L-Arabinose could repress DSS-induced colitis and inhibit p38-/p65-dependent inflammation activation. Besides that, our data revealed that L-Arabinose modulated gut microbiota disturbed by DSS treatment. Additionally, by antibiotic treatment, the perturbed gut microbiota was responsible for the suppressive effects of L-Arabinose on DSS-induced colitis. Lastly, Caco-2 cells was used to confirm the protective effects of L-Arabinose. As expected, the expression levels of pro-inflammatory proteins in Caco-2 cells treated with L-Arabinose in absence or presence of TNFα. Our work suggested that L-Arabinose exert anti-inflammation effect in DSS-induced colitis. These beneficial effects may be related to the diversity and composition of the gut microbiota regulated by L-Arabinose. L-Arabinose could be a remarkable candidate as a functional food or novel therapeutic strategies for intestinal health.",
        "keywords": "",
        "authors": [
            {
                "name": "Yan Li",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Haiou Pan",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Jin-Xin Liu",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Tingting Li",
                "org": "Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Shengnan Liu",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Wenli Shi",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Chao Sun",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Mingcong Fan",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Lamei Xue",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Yu Wang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Chenzhipeng Nie",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            },
            {
                "name": "Hao Ying",
                "org": "Chinese Academy of Sciences Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, Shanghai, China"
            },
            {
                "name": "Li Wang",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment & Technology, State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Nanjing 210037, Jiangsu, China"
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2019
    },
    "92X6ht5o": {
        "id": "92X6ht5o",
        "title": "Enantioselective effects of imazethapyr on Arabidopsis thaliana root exudates and rhizosphere microbes.",
        "abstract": "Imazethapyr (IM) is a chiral herbicide with two enantiomers (R-IM and S-IM). Here, we determined the enantioselective effects of IM on Arabidopsis thaliana biomass and chlorophyll content, root exudates and rhizosphere microbes after 7 days of exposure. The results suggested that 133 μg/kg R-IM enantiomer in soil slightly inhibited plant biomass but S-IM did not exert significant inhibitory effects. The rhizosphere microorganism composition was also found to have enantiomeric differences between R- and S-IM. The relative abundance of beneficial rhizosphere microbes such as Bacillus and Ramlibacter increased much more with R-IM treatment than with S-IM treatment, indicating that the rhizosphere recruited some beneficial microbes to resist the herbicide stress. The IM enantiomers exerted a significant influence on root exudates with enantioselectivity. R-IM resulted in higher levels of most amino acids, organic acids, sugars and other metabolites after 7 days of exposure; few metabolites were increased by only the S-IM treatment. The correlation analyses between compounds (sugars, amino acids and organic acid) and microbes at the genus level revealed that the number of microbes was more positively correlated with organic acids than other compounds, indicating that organic acids can attract more microbes than amino acids and sugars. Some organic acids, such as 3-hydroxybutyric acid, may be a carbon source for the beneficial microbe Ramlibacter. This study increases the understanding of the differences in IM enantiomer toxicity with respect to plant physiological activity and soil microorganisms.",
        "keywords": [
            "Arabidopsis thaliana",
            "Chiral herbicides",
            "Enantioselective",
            "Rhizosphere microorganisms",
            "Root exudates"
        ],
        "authors": [
            {
                "name": "Wanyue Liu",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Qianqiu Zhao",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Nuohan Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2020
    },
    "SJqCacVS": {
        "id": "SJqCacVS",
        "title": "Enantioselective Damage of Diclofop Acid Mediated by Oxidative Stress and Acetyl-CoA Carboxylase in Nontarget Plant Arabidopsis thaliana",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "meirong zhao",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "tao lu",
                "org": ""
            },
            {
                "name": "quan zhang",
                "org": ""
            },
            {
                "name": "weiping liu",
                "org": ""
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2012
    },
    "OEsv3a56": {
        "id": "OEsv3a56",
        "title": "An anonymous remote attestation for trusted cloud computing",
        "abstract": "Cloud computing provides users and companies a cost-efficient and flexible service. However, for a cloud computing client, one of most worrying problems is that IT infrastructure is under control of the cloud provider. To secure cloud users' computation, efficient remote attestation protocol is required. In this paper, by combining trusted computing and dynamic accumulators, we put forward an anonymous remote attestation scheme for cloud computing service provider. Under the help of online or offline trusted third parties, a user can attest remote trusted nodes and establish a secure communication. In addition, the scheme can also protect privacy of trusted nodes and greatly reduce the cost of storage and management.",
        "keywords": [
            "trusted cloud computing",
            "offline trusted third parties",
            "cloud computing service provider",
            "data privacy",
            "dynamic accumulators",
            "it infrastructure",
            "cloud computing client",
            "cloud computing",
            "trusted computing",
            "storage cost",
            "remote attestation",
            "secure communication",
            "cloud provider",
            "flexible service",
            "remote attestation protocol",
            "business data processing",
            "anonymous remote attestation",
            "cloud user computation",
            "cost-efficient service",
            "security of data"
        ],
        "authors": [
            {
                "name": "Yong Zhang",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Xiangxue Li",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            }
        ],
        "venue": "Proceedings - 2012 IEEE 2nd International Conference on Cloud Computing and Intelligence Systems, IEEE CCIS 2012",
        "year": 2013
    },
    "eIMXt4eY": {
        "id": "eIMXt4eY",
        "title": "Vicarious calibration of GOES visible channel using GOME-2",
        "abstract": "GOES Imager visible channel has no onboard calibration devices. While many methods of vicarious calibration exist, one of few viable options to render the calibration absolute is to make it traceable to MODIS. However, the spectral response function for the visible band of MODIS is very different from that of GOES Imager visible channel. In this study we use the hyperspectral data collected by GOME-2 to characterize the difference due to SRF under various conditions. It was found that this difference tends to be stable for bright clouds, although there are variations among GOES. This results offer guidance for target selection in inter-calibration with MODIS.",
        "keywords": [
            "calibration",
            "goes imager visible channel",
            "modis",
            "image resolution",
            "spectral analysis",
            "spectral characterization",
            "goes",
            "artificial satellites",
            "hyperspectral data",
            "image sensors",
            "geophysical image processing",
            "gome-2",
            "radiometers",
            "spectral response function",
            "target selection",
            "srf",
            "vicarious calibration",
            "visible channel",
            "calibration render",
            "reflectivity",
            "hyperspectral imaging"
        ],
        "authors": [
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Trevor Beck",
                "org": ""
            }
        ],
        "venue": "IGARSS",
        "year": 2011
    },
    "MIg0UF9i": {
        "id": "MIg0UF9i",
        "title": "Tightly Secure Non-Interactive Multisignatures in the Plain Public Key Model",
        "abstract": "Multisignature scheme allows a group of signers to generate a compact signature on a common document that certifies they endorsed the message. However, the existing state of the art multisignatures often suffers from the following problems: impractical key setup assumptions, loose security reductions and inefficient signature verification. In this paper, we propose a non-interactive multisignature scheme with tight security reduction in the random oracle model. Our proposed multisignatures address the above three problems by achieving: provable security in the plain public key model; tight security reduction under the standard Computational Diffie–Hellman (CDH) assumption and O(1) computational time for signature verification through pre-computation. Hence, our non-interactive multisignatures are of great use in routing authentication of networks.",
        "keywords": [
            "plain public key model",
            "provable security",
            "rogue key attacks",
            "multisignatures",
            "tight security"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Xinli Huang",
                "org": ""
            }
        ],
        "venue": "Informatica, Lith. Acad. Sci.",
        "year": 2012
    },
    "r7ZcOp8r": {
        "id": "r7ZcOp8r",
        "title": "Bilinear-pairings Based Designated-verifier Threshold Proxy Signature Scheme",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Qingshui Xue",
                "org": ""
            },
            {
                "name": "Fengying Li",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            },
            {
                "name": "Jiping Zhang",
                "org": ""
            },
            {
                "name": "Zhenfu Cao",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Security and Management",
        "year": 2009
    },
    "FwTMBsWj": {
        "id": "FwTMBsWj",
        "title": "Adaptively Secure Threshold Signature Scheme in the Standard Model",
        "abstract": "We propose a distributed key generation protocol for pairing-based cryptosystems which is adaptively secure in the erasure-free and secure channel model, and at the same time completely avoids the use of interactive zero-knowledge proofs. Utilizing it as the threshold key generation protocol, we present a secure (t,n) threshold signature scheme based on the Waters' signature scheme. We prove that our scheme is unforgeable and robust against any adaptive adversary who can choose players for corruption at any time during the run of the protocols and make adaptive chosen-message attacks. And the security proof of ours is in the standard model (without random oracles). In addition our scheme achieves optimal resilience, that is, the adversary can corrupt any t",
        "keywords": [
            "adaptively secure threshold signature",
            "threshold signature",
            "threshold signature scheme",
            "standard model",
            "optimal resilience",
            "signature scheme",
            "secure channel model",
            "computational diffie-hellman problem",
            "threshold key generation protocol",
            "interactive zero-knowledge proof",
            "adaptive adversary",
            "provable security.",
            "adaptively secure",
            "key generation protocol",
            "distributed key generation",
            "adaptive chosen-message attack",
            "zero knowledge proof",
            "random oracle",
            "provable security"
        ],
        "authors": [
            {
                "name": "Zecheng Wang",
                "org": "Department of Computer Sci. & Tech., East China Normal University, 200062 Shanghai, China and Dept. of Comp. Sci. & Tech., Anhui Univ. of Finance and Economics, 233041 Bengbu, China, e-mail: w5205 ..."
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Sci. & Tech., East China Normal University, 200062 Shanghai, China"
            },
            {
                "name": "Zhibin Li",
                "org": "Department of Computer Sci. & Tech., East China Normal University, 200062 Shanghai, China"
            }
        ],
        "venue": "Informatica, Lith. Acad. Sci.",
        "year": 2009
    },
    "JX4OHBfl": {
        "id": "JX4OHBfl",
        "title": "Combined effect of copper and cadmium on heavy metal ion bioaccumulation and antioxidant enzymes induction in Chlorella vulgaris.",
        "abstract": "The relationships between metal uptake and antioxidant enzyme activities or a response to membrane lipid peroxidation (i.e.,\n malondialdehyde production) in Chlorella vulgaris exposed to Cu and Cd compounds singly and in combination were investigated. The results showed that bioaccumulation of a\n single metal was influenced by the presence of the other metal. The activities of superoxide dismutase and peroxidase increased\n to more than fivefold of the control after exposure to Cu(1.5 μM) alone or to Cu(1.5 μM) with Cd mixtures. Malondialdehyde\n levels in C. vulgaris also increased to approximately twofold of the control after exposure to high concentration of Cu(1.5 μM) alone or to Cu\n and Cd mixtures. However, Cd alone did not significantly increase the levels of antioxidant enzymes or malondialdehyde.",
        "keywords": [
            "antioxidant enzyme",
            "bioaccumulation",
            "cadmium",
            "copper"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Jingjing Li",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Liwei Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Tao Lu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Hongyu Ran",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2011
    },
    "TyHGuacm": {
        "id": "TyHGuacm",
        "title": "Nitric oxide enhanced reduction in a rotating drum biofilter coupled with absorption by Fe II (EDTA): Nitric oxide enhanced reduction in a rotating drum biofilter",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qizhou dai",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yifeng jiang",
                "org": ""
            },
            {
                "name": "jianmeng chen",
                "org": ""
            }
        ],
        "venue": "Journal of Chemical Technology & Biotechnology",
        "year": 2013
    },
    "NOnMWyP7": {
        "id": "NOnMWyP7",
        "title": "Efficient CDH-based verifiably encrypted signatures with optimal bandwidth in the standard model",
        "abstract": "Exchanging items over mobile ad hoc network has been considered a challenging issue in recent years. To tackle this challenge, Verifiably Encrypted Signature (VES), which is employed as primitives when designing a large class of protocols such as certified email, fair exchange, and contract signing in wireless communication, provides a possible solution. However, the limited communication band, low computational ability and weak energy power restrict many existing verifiably encrypted signatures to be applied in ad hoc networks directly. In this paper, we propose a compact verifiably encrypted signature scheme without random oracles based on the Computational Diffie-Hellman problem (CDH) with pairings. Comparing with prior works, our scheme achieves the following desired features: (1) Our verifiably encrypted signature has compact size (only two group elements) which is optimal for both Elgamal encryption and the Waters signature; (2) The scheme is more efficient in terms of signature generation and verification; (3) Our scheme also achieves provable security under a standard complexity assumption in the standard model. Apparently, our schemes are amongst the most efficient solutions in terms of both signature size and computation (optimal ) because these features are important in wireless communication due to limited bandwidth and power. It can be surely applied flexibly to many secure exchange circumstances in mobile ad hoc network that solely allows the minimum cryptographic implementation.",
        "keywords": [
            "compact verifiably encrypted signature",
            "efficient solution",
            "compact size",
            "wireless communication",
            "signature size",
            "existing verifiably encrypted signature",
            "verifiably encrypted signature",
            "waters signature",
            "limited communication band",
            "optimal bandwidth",
            "signature generation",
            "standard model",
            "ad hoc network"
        ],
        "authors": [
            {
                "name": "Yuan Zhou",
                "org": "Department of Computer Science and Technology, East China Normal University and Network Emergency Response Technical Team/Coordination Center, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            }
        ],
        "venue": "ADHOC-NOW",
        "year": 2011
    },
    "3lviZdsw": {
        "id": "3lviZdsw",
        "title": "A practical optimal padding for signature schemes",
        "abstract": "A digital signature scheme that achieves an optimal bandwidth (generating signatures as short as possible) is called an optimal signature scheme. The previous optimal signature schemes all need the random permutations (or the ideal ciphers) with large block size as building blocks. However, the practical cipher with large block size such as Halevi and Rogaway's CMC-mode should call the underlying secure block cipher with small block size many times each time. This makes the previous optimal signature schemes which use the large domain permutation (or the ideal cipher) less efficient in the real world, even if there exist the methods that can encipher the messages with larger domain. On the other hand, all the practical signature schemes are not optimal in bandwidth including PSS-R, FDH, DSA, etc. Hence, the problem on how to design a practical, efficient and optimal signature scheme remains open. This paper uses two random oracles and an ideal cipher with a smaller block size to design an optimal padding for signature schemes. The ideal cipher in our scheme can be implemented with a truly real block cipher (e.g. AES). Therefore, we provide a perfect solution to the open problem. More precisely, we design a practical, efficient and optimal signature scheme. Particularly, in the case of RSA, the padding leads the signature scheme to achieve not only optimality in bandwidth but also a tight security.",
        "keywords": [
            "practical cipher",
            "previous optimal signature scheme",
            "optimal padding",
            "practical signature scheme",
            "digital signature scheme",
            "signature scheme",
            "optimal signature scheme",
            "practical optimal",
            "optimal bandwidth",
            "ideal cipher",
            "large block size",
            "block cipher",
            "random oracle model",
            "random oracle",
            "random permutation"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Computer Science & Technology Department, East China Normal University, Shanghai, China"
            },
            {
                "name": "Zhibin Li",
                "org": "Computer Science & Technology Department, East China Normal University, Shanghai, China"
            },
            {
                "name": "Zhijie Chen",
                "org": "Department of Mathematics, East China Normal University, Shanghai, China"
            },
            {
                "name": "Siman Yang",
                "org": "Department of Mathematics, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "CT-RSA",
        "year": 2007
    },
    "Vz5dxu0J": {
        "id": "Vz5dxu0J",
        "title": "Study of the retrogradation behaviour of rice cake using rapid visco analyser, Fourier transform infrared spectroscopy and X-ray analysis",
        "abstract": "Summary Retrogradation of gelatinised starch is the main phenomenon that influences the texture of MiGao (rice cake). The hardness of the MiGao increased during stored at 25 °C for 5 days. Rapid visco analyser (RVA), Fourier transform infrared (FT-IR) spectroscopy and X-ray were quantified to analysis the retrogradation behaviour of MiGao. The most significant change in the pasting curve was the increase in peak viscosity over time measured with an RVA. FT-IR indicated changes in crystallinity of the MiGao crumb. The X-ray diffraction patterns could be classified as typical of A-type starch for the fresh MiGao. With aging, the B type structure increases, while the A-type structure remains virtually unchanged. All the results suggested that the main mechanism underlying the changes in properties is suggested to be slow amylopectin crystallisation. © 2010 The Authors. Journal compilation © 2010 Institute of Food Science and Technology.",
        "keywords": [
            "fourier transform infrared",
            "rapid visco analyser",
            "rice cake",
            "texture",
            "x-ray"
        ],
        "authors": [
            {
                "name": "Ying Ji",
                "org": "Dalian Nationalities University(Dalian Nationalities University),Dalian,China"
            },
            {
                "name": "Kexue Zhu",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Huiming Zhou",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "HaiFeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "International Journal of Food Science and Technology",
        "year": 2010
    },
    "ibIXfeAn": {
        "id": "ibIXfeAn",
        "title": "Acute toxicity of the fungicide azoxystrobin on the diatom Phaeodactylum tricornutum.",
        "abstract": "Azoxystrobin (AZ) is an effective broad-spectrum fungicide. Due to its extensive application, AZ is detectable in aquatic ecosystems and thus influences aquatic organisms. In this study, the acute toxicity (96 h) of AZ at concentrations of 1.0 mg/L and 5.0 mg/L on the diatom Phaeodactylum tricornutum were examined. At the tested concentrations, AZ significantly inhibited P. tricornutum growth and destroyed its cellular structure. Furthermore, the mechanisms of AZ-induced toxicity on P. tricornutum changed as the exposure time extended. Forty-eight hours after exposure, AZ inhibited P. tricornutum growth primarily via inducing oxidative stress, which increased the activity of two main antioxidant enzymes, superoxide dismutase and peroxidase, and inhibited energy metabolism. However, after 96 h of treatment, the decline in the photosynthetic capacity of P. tricornutum demonstrated that the photosystem was the main AZ target. The pigment content and expression levels of genes related to photosynthetic electron transfer reactions were also significantly decreased. The present study describes AZ toxicity in P. tricornutum and is very valuable for assessing the environmental risk of AZ.",
        "keywords": [
            "Azoxystrobin",
            "Energy metabolism",
            "Oxidative stress",
            "Phaeodactylum tricornutum",
            "Photosynthesis"
        ],
        "authors": [
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Wanyue Liu",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China."
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhanyu Fu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2018
    },
    "q3Lojm7s": {
        "id": "q3Lojm7s",
        "title": "How strong is carbon cycle-climate feedback under global warming?",
        "abstract": "The behavior of the coupled carbon cycle and physical climate system in a global warming scenario is studied using an Earth system model including the atmosphere, land, ocean, and the carbon cycle embedded in these components. A fully coupled carbon-climate simulation and several sensitivity runs were conducted for the period of 1860–2100 with prescribed IPCC-SRES-A1B emission scenario. Results indicate a positive feedback to global warming from the interactive carbon cycle, with an additional increase of 90 ppmv in the atmospheric CO2, and 0.6 degree additional warming, thus confirming recent results from the Hadley Centre and IPSL. However, the changes in various carbon pools are more modest, largely due to the multiple limiting factors constraining terrestrial productivity and carbon loss. The large differences among the three models are manifestations of some of the poorly constrained processes such as the global strength of the CO2 fertilization effect and the turnover time and rates of soil decomposition.",
        "keywords": [
            "positive feedback",
            "system modeling",
            "limiting factor",
            "global change",
            "carbon cycle",
            "global warming"
        ],
        "authors": [
            {
                "name": "Ning Zeng",
                "org": "Department of Meteorology and Earth System Science Interdisciplinary Center, University of Maryland, College Park, Maryland, USA"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Meteorology and Earth System Science Interdisciplinary Center, University of Maryland, College Park, Maryland, USA"
            },
            {
                "name": "Ernesto Munoz",
                "org": "Department of Meteorology and Earth System Science Interdisciplinary Center, University of Maryland, College Park, Maryland, USA"
            },
            {
                "name": "Roberto Iacono",
                "org": "Climate Section, Ente per le Nuove Tecnologie, l'Energia, e l'Ambiente, Rome, Italy"
            }
        ],
        "venue": "Geophysical Research Letters",
        "year": 2004
    },
    "ES5gVpOo": {
        "id": "ES5gVpOo",
        "title": "PWG: Progressive Weight-Growth Algorithm for LDPC Codes.",
        "abstract": "Given specified parameters, the number of check nodes, the expected girth and the variable node degrees, the Progressive Weight- Growth (PWG) algorithm is proposed to generate high rate low-density parity-check (LDPC) codes. Based on the theoretic foundation that is to investigate the girth impact by adding/removing variable nodes and edges of the Tanner graph, the PWG progressively increases column weights of the parity check matrix without violating the constraints defined by the given parameters. The analysis of the computational complexity and the simulation of code performance show that the LDPC codes by the PWG provide better or comparable performance in comparison with LDPC codes by some well-known methods (e.g., Mackay's random constructions, the PEG algorithm, and the bit-filling algorithm). Copyright ? 2014 The Institute of Electronics, Information and Communication Engineers.",
        "keywords": [
            "girth",
            "ldpc code",
            "progressive weight growth"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Qingji Zheng",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Dong Zheng",
                "org": ""
            },
            {
                "name": "Kefei Chen",
                "org": ""
            }
        ],
        "venue": "IEICE Transactions",
        "year": 2014
    },
    "2vbP7GtV": {
        "id": "2vbP7GtV",
        "title": "Democratic group signatures with linkability from gap Diffie-Hellman group",
        "abstract": "Democratic group signatures (DGSs) attract many researchers due to their appealing properties, i.e., anonymity, traceability\n and no group manager. Security results of existing work are based on decisional Diffie-Hellman (DDH) assumption. In this paper,\n we present a democratic group signature scheme based on any gap Diffie-Hellman (GDH) group where DDH problem is easily but\n computational Diffe-Hellman (CDH) problem is hard to be solved. Besides the properties of ordinary DGSs, our scheme also provides\n the property of linkability, i.e., any public verifier can tell whether two group signatures are generated using the same\n private key. Security properties of our scheme employ a new and independently interesting decisional product Diffie-Hellman\n (DPDH) assumption which is weaker than DDH one.",
        "keywords": [
            "traceability",
            "gdh group",
            "democratic group signature",
            "linkability clc number: tp 309 document code: a",
            "linkability",
            "anonymity",
            "GDH group",
            "TP 309"
        ],
        "authors": [
            {
                "name": "yanbin liu 刘彦宾",
                "org": "ZunYi Normal College Department of Computer Science Zunyi 563002 China"
            },
            {
                "name": "xiangxue li 李祥学",
                "org": "Shanghai Jiaotong University School of Information Security Engineering Shanghai 200240 China"
            },
            {
                "name": "haifeng qian 钱海峰",
                "org": "East China Normal University Computer Science and Technology Department Shanghai 200062 China"
            },
            {
                "name": "wenzheng zhang 张文政",
                "org": "National Laboratory for Modern Communications Chengdu 610041 China"
            }
        ],
        "venue": "Journal of Shanghai Jiaotong University (science)",
        "year": 2008
    },
    "SBmkwJ9p": {
        "id": "SBmkwJ9p",
        "title": "Histopathological and proteomic analysis of hepatic tissue from adult male zebrafish exposed to 17β-estradiol.",
        "abstract": "17β-Estradiol (E2) is known to contribute significantly a large extent to the estrogenicity in aquatic system. In the present study, two-dimensional gel electrophoresis (2-DE) and mass spectrometry (MALDI-TOF-TOF MS), combined with histopathological analysis, was used to screen hepatic responses in adult male zebrafish. Eight proteins were found to be up-regulated more than 2-fold, whereas five protein spots were down-regulated more than 2-fold after 1nM E2 treatment for 14 days, which had caused histological effects in zebrafish livers. These differentially expressed proteins accounted for a variety of cellular biological processes, such as response to oxidative stress, cell surface receptor-linked signal transduction, oxidation-reduction and cellular calcium ion homeostasis. The results demonstrated that E2 comprehensively influenced a variety of cellular and biological processes in zebrafish. Moreover, the proteomic responses elicited in zebrafish allow us to better understand the underlying mechanisms of endocrine-disrupting chemicals (EDCs)-induced toxicity fully.",
        "keywords": [
            "zebrafish",
            "endocrine disrupting effects",
            "proteome",
            "17β-estradiol",
            "liver",
            "two dimensional gel electrophoresis",
            "biological process",
            "mass spectrometry",
            "signal transduction"
        ],
        "authors": [
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Xiangxiang Zhang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Dezhao Lu",
                "org": "College of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Environmental toxicology and pharmacology",
        "year": 2010
    },
    "dfVlA0cN": {
        "id": "dfVlA0cN",
        "title": "An Encrypted Database with Enforced Access Control and Blockchain Validation.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhimei Sui",
                "org": "East China Normal University"
            },
            {
                "name": "Shangqi Lai",
                "org": "Monash University, Clayton, Australia"
            },
            {
                "name": "Cong Zuo",
                "org": "Monash University, Clayton, Australia"
            },
            {
                "name": "Xingliang Yuan",
                "org": "Monash University, Clayton, Australia"
            },
            {
                "name": "Joseph K. Liu",
                "org": "Monash University, Clayton, Australia"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University, Shanghai, China"
            }
        ],
        "venue": "Inscrypt",
        "year": 2018
    },
    "OmP34vH5": {
        "id": "OmP34vH5",
        "title": "The effect of social diversity on regional innovation: measures and empirical evidence",
        "abstract": "",
        "keywords": [
            "economic development",
            "intellectual property",
            "openness",
            "foresight"
        ],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "roger r stough",
                "org": ""
            }
        ],
        "venue": "International Journal of Foresight and Innovation Policy",
        "year": 2011
    },
    "DwP4E9mp": {
        "id": "DwP4E9mp",
        "title": "Simulatability and security of certificateless threshold signatures",
        "abstract": "We analyze the relationship between the notion of certificateless public key cryptography (CL-PKC) and identity-based schemes without a trusted private key generator (PKG), formally define the security of certificateless threshold signatures, and propose a concrete implementation based on bilinear pairings. To exhibit the security of our proposal, we develop the theory of simulatability and relationship between the certificateless threshold signatures and the underlying (non-threshold) ID-based signatures. We show that the proposed scheme is robust and existentially unforgeable against adaptively chosen message attacks under CDH assumption in the random oracle model.",
        "keywords": [
            "existentially unforgeable",
            "cdh assumption",
            "identity-based scheme",
            "certificateless public key cryptography",
            "message attack",
            "id-based signature",
            "private key generator",
            "certificateless threshold signature",
            "concrete implementation",
            "bilinear pairings",
            "public key cryptography",
            "digital signature",
            "provable security",
            "key escrow",
            "random oracle model"
        ],
        "authors": [
            {
                "name": "Licheng Wang",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People's Republic of China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People's Republic of China"
            },
            {
                "name": "Xiangxue Li",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People's Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People's Republic of China"
            }
        ],
        "venue": "Inf. Sci.",
        "year": 2007
    },
    "1FHS7tbW": {
        "id": "1FHS7tbW",
        "title": "Understanding the molecular weight distribution, in vitro digestibility and rheological properties of the deep-fried wheat starch.",
        "abstract": "The effects of frying temperature on the properties of wheat starch were investigated, including the microstructure, weight-average molar mass (M), crystalline properties, functional groups, in vitro digestibility, static rheological properties, swelling power and solubility. SEM micrographs showed that the disc-shaped starch granules ruptured after being fried, and formed a continuous and dense gel structure. With the increasing frying temperature, the starch molecules underwent violent degradation, and the M decreased from 3.04 × 10 g/mol to 0.80 × 10 g/mol. The XRD and FTIR data indicated the formation of starch-lipid complexes during the frying process. In vitro digestion analysis revealed that the digestion rate of starch decreased, while the content of resistant starch (RS) increased after being fried. Besides, the shear stability of fried starch increased, whereas its swelling power and solubility decreased. These significant variations in physicochemical properties of starch could provide scientific basis for further improving the quality of instant noodles.",
        "keywords": [
            "Deep-frying",
            "FTIR",
            "In vitro digestion",
            "Physicochemical properties",
            "Starch-lipid complexes"
        ],
        "authors": [
            {
                "name": "Yi Yang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Tingting Li",
                "org": "Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, 159 Longpan Road, Nanjing 210037, China."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, Jiangnan University, 1800, Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            }
        ],
        "venue": "Food chemistry",
        "year": 2020
    },
    "V6jTEda9": {
        "id": "V6jTEda9",
        "title": "Effect of Extrusion on the Hydrophilic Antioxidant Capacity of Four Whole Grains",
        "abstract": "",
        "keywords": [
            "hplc"
        ],
        "authors": [
            {
                "name": "lingxiao yang",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "lilin cheng",
                "org": ""
            },
            {
                "name": "zhonghua gu",
                "org": ""
            },
            {
                "name": "dan hua",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            }
        ],
        "venue": "Journal of Food and Nutrition Research",
        "year": 2014
    },
    "Bt7qQ2Fk": {
        "id": "Bt7qQ2Fk",
        "title": "The distribution variance of airborne microorganisms in urban and rural environments.",
        "abstract": "Microorganisms are ubiquitous in the atmosphere, where they can disperse for a long distance. However, it remains poorly understood how these airborne microorganisms vary and which factors influence the microbial distribution in different anthropogenic activity regions. To explore the regional differences of bacteria and fungi in airborne particles, PM and PM samples were collected in the urban and rural areas of Hangzhou. The bacterial and fungal communities in the urban atmosphere was more similar to each other than those in the rural atmosphere. Analyses conducted by the concentration weighted trajectory model demonstrated that the local environment contributed more to the similarity of airborne bacteria and fungi compared with the atmospheric transport. The concentrations of local air pollutants (PM, PM, NO, SO and CO) were positively correlated with the similarity of the bacterial and fungal communities. Additionally, the concentrations of these air pollutants in the urban site were about 1.5 times than those in the rural site. This implicated that anthropogenic activity, which is the essential cause of air pollutants, influenced the similarity of airborne bacteria and fungi in the urban area. This work ascertains the outdoor bacterial and fungal distribution in the urban and the rural atmosphere and provides a prospective model for studying the contributing factors of airborne bacteria and fungi.",
        "keywords": [
            "Air pollutant",
            "Airborne bacteria",
            "Airborne fungi",
            "Atmospheric transport",
            "Rural",
            "Urban"
        ],
        "authors": [
            {
                "name": "Huan Liu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Zhichao Hu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Meng Zhou",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Jiajie Hu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Xiangwu Yao",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Hao Zhang",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Zheng Li",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Liping Lou",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Chuanwu Xi",
                "org": "Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, USA."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, China."
            },
            {
                "name": "Chunyan Li",
                "org": "College of Resources and Environment, Northeast Agricultural University, Harbin, 150030, China."
            },
            {
                "name": "Xiangyang Xu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Ping Zheng",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Baolan Hu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou, 310058, China; Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, 310058, China. Electronic address: blhu@zju.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2019
    },
    "xp71dGde": {
        "id": "xp71dGde",
        "title": "Generating signatures with optimal overhead: practical paddings for signature schemes.",
        "abstract": "Optimal signatures (generating signatures as short as possible), which achieve the\n         optimal bandwidth for communication, are extremely useful in bandwidth‐critical networks.\n         Previous approaches use the random permutations with large block size as building\n         blocks, which incurs less efficient implementations in the real world. Meanwhile,\n         all the practical signature schemes are not optimal in bandwidth including PSS‐R (probabilistic\n         signature scheme with message recovery ), FDH ( Full Domain Hash), and DSA (Digital\n         Signature Algorithm). This paper presents three constructions for optimal signature\n         schemes. All the proposals use both the random oracles and the ideal ciphers with\n         smaller block sizes as building blocks to obtain optimal paddings for signature schemes.\n         The ideal ciphers in our schemes can be implemented by real block ciphers (e.g., AES\n         (Advanced Encryption Standard)‐256). Concrete implementations of these signature schemes\n         can utilize the trapdoor permutations of Rabin and RSA, respectively. Surprisingly,\n         RSA and Rabin (trapdoor permutations) lead to not only optimality in bandwidth but\n         also a tight security. Therefore, besides yielding secure signatures with high efficiency,\n         our proposals can also be flexibly applied to the bandwidth‐limited networks that\n         reduces the communication cost as less as possible. Copyright © 2014 John Wiley &\n         Sons, Ltd.\n      ",
        "keywords": [
            "optimal signature",
            "tight security",
            "random oracle model",
            "ideal cipher model",
            "short signature"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            },
            {
                "name": "Zhibin Li",
                "org": ""
            },
            {
                "name": "Zhijie Chen",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2014
    },
    "wuCgwIgS": {
        "id": "wuCgwIgS",
        "title": "Oxidative stress response and gene expression with atrazine exposure in adult female zebrafish (Danio rerio).",
        "abstract": "Atrazine (ATZ) is the most common pesticide of freshwater ecosystems in the world. The effects of ATZ exposure on the induction of oxidative stress and the alteration of gene expression were studied in liver and ovary samples from female zebrafish (Danio rerio). Antioxidant enzyme activities (SOD and CAT), in addition to the GSH and MDA content, in the liver altered significantly; the mRNA levels for the genes encoding these antioxidant proteins, such as Cu/Zn-Sod, Mn-Sod, Cat, and Gpx, were up-regulated significantly in the liver when zebrafish were exposed to various concentrations of ATZ for 14d. However, the mRNA induction patterns were not in accordance with those of antioxidant enzyme changes in the liver and ovary. Moreover, the transcriptional expression of mitochondrial inner membrane genes related to ROS production, such as Ucp-2 and Bcl-2, were altered significantly in high ATZ treatment groups. However, the ATZ treatment did not induce any apparent changes in the transcriptional expression of CoxI, Ndi, or ATPo6, which are related to the mitochondrial respiratory chain and ATP synthesis. To our knowledge, this is the first report to study the transcriptional effects of ATZ stress on zebrafish. The information presented in this study will be helpful in fully understanding the mechanism of oxidative stress induced by ATZ in fish.",
        "keywords": [
            "female zebrafish",
            "real-time rt-pcr",
            "oxidative stress",
            "atrazine"
        ],
        "authors": [
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Xiangxiang Zhang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Linjun Shu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Lifang Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Chemosphere",
        "year": 2010
    },
    "y5uhYI7x": {
        "id": "y5uhYI7x",
        "title": "A hybrid linear equation solver and its application in quadratic placement",
        "abstract": "This paper presents a new hybrid linear equation solver for quadratic placement. The new solver is a combination of stochastic solver and iterative solver: it is proven in this paper that an approximate LDL factorization can be obtained from random walks, and used as a preconditioner for conjugate gradient solver. Testing on real-life placement benchmarks shows a speedup of up to 7.1 times over traditional Incomplete Cholesky preconditioned Conjugate Gradient (ICCG).",
        "keywords": [
            "random walk",
            "conjugate gradient",
            "iterative solver",
            "conjugate gradient solver",
            "hybrid linear equation solver",
            "quadratic placement",
            "real-life placement benchmarks",
            "new solver",
            "approximate ldl factorization",
            "new hybrid linear equation",
            "stochastic solver",
            "benchmark testing",
            "cholesky factorization",
            "integrated circuit design",
            "vlsi",
            "linear equations",
            "cost function",
            "equilibrium point",
            "positive definite",
            "vlsi design",
            "simulated annealing"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Minnesota Univ., Minneapolis, MN, USA"
            },
            {
                "name": "S. S. Sapatnekar",
                "org": "Minnesota Univ., Minneapolis, MN, USA"
            }
        ],
        "venue": "ICCAD",
        "year": 2005
    },
    "yx0JbkJt": {
        "id": "yx0JbkJt",
        "title": "Analyses of gene expression and physiological changes in Microcystis aeruginosa reveal the phytotoxicities of three environmental pollutants.",
        "abstract": "When the concentrations of ampicillin (Amp), atrazine (Atr) and cadmium chloride (Cd) reach excessive quantities, they become toxic to aquatic organisms. Due to the acceleration of the industrialization and the intensification of human activities, the incidence and concentrations of these types of pollutants in aquatic systems are increasing. The primary purpose of this study was to evaluate the short-term effects of Amp, Atr and Cd on the physiological indices and gene expression levels in Microcystis aeruginosa. These three pollutants significantly induced antioxidant activity but continuously accelerated the cellular oxidative damage in microalgae, which suggests an imbalance between the oxidant and the antioxidant systems. Amp, Atr and Cd also decreased the transcription of psaB, psbD1 and rbcL; the lowest transcription of these genes was only 38.1, 23.7 and 7% of the control, respectively. These three pollutants affected nitrogen (N) and phosphorous (P) uptake by inhibiting the transcription of N or P absorbing and transporting related genes, and they down regulated the transcription of microcystin-related genes, which caused a decrease of microcystin levels; and the lowest level of microcystin was only 42.4% of the control. Our results suggest that these pollutants may cause pleiotropic effects on algal growth and physiological and biochemical reactions, and they may even affect secondary metabolic processes.",
        "keywords": [
            "microcystis aeruginosa",
            "ampicillin",
            "microcystin",
            "cadmium chloride",
            "atrazine",
            "gene transcription"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Jun Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Dongming Zhou",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zuoguo Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Lin Zhang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Ecotoxicology (London, England)",
        "year": 2012
    },
    "yLVz9NWv": {
        "id": "yLVz9NWv",
        "title": "Combined Effect of Copper and Cadmium on Heavy Metal Ion Bioaccumulation and Antioxidant Enzymes Induction in  ",
        "abstract": "The relationships between metal uptake and antioxidant enzyme activities or a response to membrane lipid peroxidation (i.e., malondialdehyde production) in  exposed to Cu and Cd compounds singly and in combination were investigated. The results showed that bioaccumulation of a single metal was influenced by the presence of the other metal. The activities of superoxide dismutase and peroxidase increased to more than fivefold of the control after exposure to Cu(1.5 μM) alone or to Cu(1.5 μM) with Cd mixtures. Malondialdehyde levels in  also increased to approximately twofold of the control after exposure to high concentration of Cu(1.5 μM) alone or to Cu and Cd mixtures. However, Cd alone did not significantly increase the levels of antioxidant enzymes or malondialdehyde.",
        "keywords": [
            "Antioxidant enzyme",
            "Bioaccumulation",
            "Cadmium",
            "Copper"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Jingjing Li",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Tao Lu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Hongyu Ran",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Bulletin of Environmental Contamination and Toxicology",
        "year": 2011
    },
    "dtDxxxcB": {
        "id": "dtDxxxcB",
        "title": "Regional systems of entrepreneurship: the nexus of human capital, knowledge and new firm formation",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zoltan j acs",
                "org": ""
            },
            {
                "name": "roger r stough",
                "org": ""
            }
        ],
        "venue": "Journal of Economic Geography",
        "year": 2013
    },
    "Gsctyds8": {
        "id": "Gsctyds8",
        "title": "Hierarchical random-walk algorithms for power grid analysis",
        "abstract": "We present a power grid analyzer that combines a divide-and-conquer strategy with a random-walk engine. A single-level hierarchical method is first described and then extended to multilevel and \"virtual-layer\" hierarchy. Experimental results show that these algorithms not only achieve speedups over the generic random-walk method, but also are more robust in solving various types of industrial circuits. For example, a 71K-node circuit is solved in 4.16 seconds, showing a more than 4 times speedup over the generic method; a 348K-node wire-bond power grid, for which the performance of the generic method degrades, is solved in 75.88 seconds.",
        "keywords": [
            "divide-and-conquer strategy",
            "generic method degrades",
            "hierarchical random-walk algorithms",
            "random-walk engine",
            "generic random-walk method",
            "industrial circuit",
            "power grid analysis",
            "single-level hierarchical method",
            "vlsi",
            "circuit complexity",
            "hierarchical random-walk algorithm",
            "power integrated circuits",
            "wire-bond power grid",
            "divide and conquer methods",
            "generic method",
            "transient analysis",
            "power grid analyzer",
            "random walk",
            "divide and conquer"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "University of Minnesota, Minneapolis, MN"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota, Minneapolis, MN"
            }
        ],
        "venue": "ASP-DAC",
        "year": 2004
    },
    "EBdhMBV6": {
        "id": "EBdhMBV6",
        "title": "Enantioselective Oxidative Stress Induced by <Emphasis Type=\"Italic\">S</Emphasis>- and Rac-metolachlor in Wheat (<Emphasis Type=\"Italic\">Triticum aestivum</Emphasis> L.) Seedlings",
        "abstract": "The unfounded use of chiral pesticides has caused widespread concern. In this study, the enantioselective effects of S- and racemic (Rac)-metolachlor on the oxidative stress of wheat seedlings was determined based on physiological and gene transcription differences. Growth inhibition increased with increasing concentrations of tested metolachlor, and S-metolachlor had a stronger inhibitory effect than did Rac-metolachlor. Root growth was also significantly inhibited, but no enantioselective effects from the tested concentrations of the metolachlor enantiomers were observed. At a concentration of 5 mg L−1, the maximal fresh weight inhibition reached 63.7% and 53.8% for S-metolachlor and Rac-metolachlor, respectively. In response to the S-metolachlor treatment, the maximum level of superoxide anions and malondialdehyde (MDA) increased to 1.73 and 2.55 times that in response to the control treatment, both of which were greater than those in response to the Rac-metolachlor treatment. The activity of superoxide dismutase (SOD) also increased in response to the S-metolachlor treatment, but the activity of peroxidase (POD) decreased. Real-time polymerase chain reaction (PCR) revealed that, compared with the Rac-metolachlor treatment, the S-metolachlor treatment attenuated the expression of several antioxidant genes. Together, these results demonstrate that S-metolachlor has a greater effect than does Rac-metolachlor on wheat seedlings.",
        "keywords": [
            "Enantioselectivity",
            " Metolachlor",
            " Antioxidant enzyme",
            " Gene transcription"
        ],
        "authors": [
            {
                "name": "Qian Qu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Bulletin of Environmental Contamination and Toxicology",
        "year": 2019
    },
    "Jcg3zmVY": {
        "id": "Jcg3zmVY",
        "title": "Regional Science Association",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "kingsley e haynes",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "3DKK79ow": {
        "id": "3DKK79ow",
        "title": "A hybrid linear equation solver and its application in quadratic placement",
        "abstract": "This paper presents a new hybrid linear equation solver for quadratic placement. The new solver is a combination of stochastic solver and iterative solver: it is proven in this paper that an approximate LDL factorization can be obtained from random walks, and used as a preconditioner for conjugate gradient solver. Testing on real-life placement benchmarks shows a speedup of up to 7.1 times over traditional Incomplete Cholesky preconditioned Conjugate Gradient (ICCG).\n\n",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Minnesota Univ., Minneapolis, MN, USA"
            },
            {
                "name": "S. S. Sapatnekar",
                "org": "Minnesota Univ., Minneapolis, MN, USA"
            }
        ],
        "venue": "ICCAD: International Conference on Computer-Aided Design",
        "year": 2005
    },
    "B9PiPBwN": {
        "id": "B9PiPBwN",
        "title": "On the security of a group signcryption scheme from distributed signcryption scheme",
        "abstract": "Signcryption denotes a cryptographic method, which can process encryption and digital signature simultaneously. So, adopting such schemes, computational cost of encryption and signature compared to traditional signature-then-encryption can be reduced to a great extent. Based on the existing distributed signcryption schemes, Kwak and Moon proposed a new distributed signcryption scheme with sender ID confidentiality and extended it to a group signcryption. Their scheme is more efficient in both communication and computation aspects. Unfortunately we will demonstrate that their scheme is insecure by identifying some security flaws. Exploring these flaws, an attacker without any secret can mount universal forging attacks. That is, anyone (not necessary the group member) can forge valid group signatures on arbitrary messages of his/her choice.",
        "keywords": [
            "arbitrary message",
            "great extent",
            "valid group signature",
            "signcryption scheme",
            "group signcryption",
            "cryptographic method",
            "group signcryption scheme",
            "computational cost",
            "group member",
            "computation aspect",
            "digital signature",
            "group signature"
        ],
        "authors": [
            {
                "name": "Haiyong Bao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, PRC"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, PRC"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, PRC"
            }
        ],
        "venue": "CANS",
        "year": 2005
    },
    "gkVuYCSZ": {
        "id": "gkVuYCSZ",
        "title": "The Structure of US R&D Policymaking: An Overview",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "kingsley e haynes",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "iDngkQ35": {
        "id": "iDngkQ35",
        "title": "Fully secure identity-based signcryption scheme with shorter signcryptext in the standard model.",
        "abstract": "Identity-based signcryption (IBSC) is a cryptographic primitive which combines both the functions of identity-based signature and identity-based encryption in a single logical step, but with the cost of computation and communication significantly less than those needed by the signature-then-encryption approach. The first proposal Yu etal. (2009). [12] for IBSC schemes without random oracles and its improvement Zhang (2010). [15] were found insecure. Recently Li and Takagi (2011). [16] presented an improved IBSC, but at the price of large signcryptext expansion and more exponentiation computation. In this paper we reconsider the first (but insecure) IBSC proposal, and find that a small modification will result in a secure IBSC. Unlike that of Li and Takagi, our scheme does not sacrifice the bandwidth and computation efficiency to achieve the security goals. We use the proof techniques of Li and Takagi to prove in the standard model its indistinguishability against adaptive chosen ciphertext attack and existential unforgeability against adaptive chosen message attack. Through comparison of computational cost and communication overhead, our scheme is amongst the most efficient IBSC schemes without random oracles. © 2012 Elsevier Ltd.",
        "keywords": [
            "existential unforgeability",
            "identity-based cryptography",
            "semantic security",
            "signcryption",
            "standard model"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Jian Weng",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            }
        ],
        "venue": "Mathematical and Computer Modelling",
        "year": 2013
    },
    "vD8qPGwx": {
        "id": "vD8qPGwx",
        "title": "Developmental neurotoxicity of Microcystis aeruginosa in the early life stages of zebrafish.",
        "abstract": "Accumulating evidence suggests that cyanotoxins can exert neurotoxic effects on exposed aquatic organisms but most studies have focused on purified toxins rather than on the more complex effects of cyanobacterial blooms. To evaluate this issue in an environmentally relevant model, we assessed the developmental neurotoxicity induced by Microcystis aeruginosa on newly hatched zebrafish. After four days of exposure, the locomotor activity of zebrafish larvae was significantly decreased with increasing algae concentration. The levels of both acetylcholinesterase (AChE) and dopamine (DA) were decreased, accompanied by a decline in ache, chrna7 and manf and a compensatory increase in nr4a2b transcription. Furthermore, the expression of nine marker genes for nervous system function or development, namely, elavl3, gap43, gfap, mbp, nestin, ngn1, nkx2.2a, shha and syn2a, similarly decreased after algal exposure. These results demonstrated that Microcystis aeruginosa exposure affected cholinergic and dopaminergic neurotransmitter systems, the transcription of key nervous system genes, and consequently the activity level of larval zebrafish. Importantly, discrepancies in the neurotoxic effects observed in this study and in previous reports that were based on exposure to pure cyanotoxin highlight the necessity for further investigation of cyanobacterial bloom mixtures when assessing the ecotoxicity of cyanobacteria.",
        "keywords": [
            "Cyanobacterial bloom mixture",
            "Gene transcriptional analysis",
            "Locomotor behavior",
            "Microcystis aeruginosa",
            "Neurotransmitter system"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Guangfu Liu",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: sunliwei@zjut.edu.cn."
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2018
    },
    "iruUOisN": {
        "id": "iruUOisN",
        "title": "Characterizing user behaviors in location-based find-and-flirt services: Anonymity and demographics - A WeChat Case Study.",
        "abstract": "WeChat, both a location-based social network (LBSN) and an online social network (OSN), is an immensely popular application in China. In this paper we specifically focus on a popular WeChat sub-service, namely, the People Nearby service, which is exemplary of a find-and-flirt service, similar to those on Momo and Tinder. Specifically, the People Nearby service reads in the current geographic location of the device to locate a list of other people using WeChat who are in the same vicinity. The user can then request to establish a WeChat friendship relation with any of the users on the list. In this paper, we explore: (i) if one gender tends to use the People Nearby service more than another; (ii) if users of People Nearby are more anonymous than ordinary WeChat users; (iii) if ordinary WeChat users are more anonymous than Twitter users. We also take an in-depth examination of the user anonymity and demographics in a combined fashion and examine: (iv) if ordinary WeChat females are more anonymous than ordinary males; (v) if People Nearby females are more anonymous than People Nearby males. By answering these questions, we will gain significant insights into modern online dating and friendship creation, insights that should be able to inform sociologists as well as designers of future find-and-flirt services.",
        "keywords": "",
        "authors": [
            {
                "name": "Minhui Xue",
                "org": "East China Normal University"
            },
            {
                "name": "Limin Yang",
                "org": "East China Normal University"
            },
            {
                "name": "Keith W. Ross",
                "org": "NYU Shanghai"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University"
            }
        ],
        "venue": "Peer-to-Peer Networking and Applications",
        "year": 2017
    },
    "nUqilKNU": {
        "id": "nUqilKNU",
        "title": "Validation of GOES-16 ABI reflective solar band calibration through reanalysis and comparison with field campaign data.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Changyong Cao",
                "org": ""
            },
            {
                "name": "Sirish Uprety",
                "org": ""
            },
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Frank Padula",
                "org": ""
            },
            {
                "name": "Aaron Pearlman",
                "org": ""
            },
            {
                "name": "Taeyoung Choi",
                "org": ""
            },
            {
                "name": "Brent Bartlett",
                "org": ""
            },
            {
                "name": "Jason Casey",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2018
    },
    "njB4jWFk": {
        "id": "njB4jWFk",
        "title": "A chip-level electrostatic discharge simulation strategy",
        "abstract": "This work presents a chip-level charged device model (CDM) electrostatic discharge (ESD) simulation method. The chip-level simulation is formulated as a DC analysis problem. A network reduction algorithm based on random walks is proposed for rapid analysis, and to support incremental design. A benchmark with a 2.3M-node VDD net and 1000 I/O pads is checked in 13 minutes, and 10 re-simulations for incremental changes take a total of 9 minutes.",
        "keywords": [
            "o pad",
            "network reduction algorithm",
            "electrostatic discharge simulation",
            "chip-level simulation",
            "simulation method",
            "dc analysis problem",
            "chip-level electrostatic discharge simulation",
            "incremental design",
            "device model",
            "rapid analysis",
            "electrostatic discharge",
            "incremental change",
            "chip-level charged device model",
            "circuit simulation",
            "random walk",
            "chip"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Minnesota Univ., Minneapolis, MN, USA"
            },
            {
                "name": "Joseph N. Kozhaya",
                "org": ""
            },
            {
                "name": "Sani R. Nassif",
                "org": ""
            },
            {
                "name": "S. S. Sapatnekar",
                "org": "Dept. of Electr. & Comput. Eng., Toronto Univ., Ont., Canada"
            }
        ],
        "venue": "ICCAD",
        "year": 2004
    },
    "KzxzRlkx": {
        "id": "KzxzRlkx",
        "title": "Non-interactive multisignatures in the plain public-key model with efficient verification",
        "abstract": "Multisignatures extend standard digital signatures to allow an ad hoc set of users to jointly sign a message. Multisignature schemes are often evaluated from the following perspectives: (1) the cryptographic assumptions underlying the schemes; (2) the operational assumptions about the bootstrapping of the schemes in practice; (3) the number of communication rounds for signing a message; (4) the time complexity for signing a message; (5) the amount of communication for signing a message; (6) the time complexity for verifying a multisignature; (7) the length of the resulting multisignatures. Existing multisignature schemes achieve various trade-offs among these measures, but none of them can achieve simultaneously the desired properties with respect to all (or even most) of these measures. In this paper, we present a novel multisignature scheme that offers desired properties with respect to the above (1)-(7) simultaneously, except that it uses random oracles (which however are often required in order to design practical schemes). In particular, our scheme is featured by its weak operational (i.e., plain public-key) model, non-interactive signing, and efficient verification.",
        "keywords": [
            "plain public-key model",
            "novel multisignature scheme",
            "non-interactive multisignatures",
            "communication round",
            "practical scheme",
            "efficient verification",
            "non-interactive signing",
            "multisignature scheme",
            "operational assumption",
            "cryptographic assumption",
            "time complexity",
            "following perspective",
            "discrete logarithm",
            "cryptography",
            "public key",
            "digital signature",
            "random oracle",
            "random oracle model",
            "bilinear map"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai 200241, PR China"
            },
            {
                "name": "Shouhuai Xu",
                "org": "Department of Computer Science, University of Texas at San Antonio, TX, USA"
            }
        ],
        "venue": "Inf. Process. Lett.",
        "year": 2010
    },
    "q8z0J8KI": {
        "id": "q8z0J8KI",
        "title": "Strong Forward Security Proxy Signature Scheme",
        "abstract": "Forward security signature scheme satisfies forward security.However,the scheme is not secure if signature's secret key is revealed.For this reason,this paper proposes a new strong forward security proxy signature scheme combining strong forward security and proxy signature,which introduces strong forward concept and overcomes limitation of the previous scheme.",
        "keywords": [
            "forward security",
            "afterward security",
            "proxy signature",
            "strong forward security"
        ],
        "authors": [
            {
                "name": "YANG Jie",
                "org": "Department of Computer Science,East China Normal University,Shanghai "
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science,East China Normal University,Shanghai "
            },
            {
                "name": "LI Zhi-bin",
                "org": "Department of Computer Science,East China Normal University,Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2008
    },
    "hEbPNR0R": {
        "id": "hEbPNR0R",
        "title": "Induction of estrogen-responsive gene transcription in the embryo, larval, juvenile and adult life stages of zebrafish as biomarkers of short-term exposure to endocrine disrupting chemicals.",
        "abstract": "Real-time quantitative RT-PCR was adopted to investigate the transcription of the estrogen-responsive genes in different developmental stages of zebrafish exposed to endocrine disrupting chemicals (EDCs). The lowest observed effect concentrations (LOECs) of 17beta-estradiol for inducing vtg1 transcription were 0.25, 0.5, 0.25 and <or=0.1 microg/L for embryo, larvae, juvenile and adult male zebrafish, respectively, while the LOECs of nonylphenol for induction of vtgs transcription were 50 microg/L in embryo and 100 microg/L in larvae and adult stages. The mRNA levels of the two vtgs were low in both the embryo and larvae stages, even at the highest 17beta-estradiol or nonylphenol exposure concentrations, while the mRNA levels in liver of adult zebrafish of the two vtgs were 10(2) or even 10(4) times higher than those of the control groups at the corresponding nonylphenol or 17beta-estradiol exposure concentrations. Similarity, the ERalpha and ERbeta mRNA levels in juvenile and adult zebrafish livers were also higher. Results suggest that in the early developmental stages of zebrafish might be more sensitive (low LOECs) to the presence of EDCs such as nonylphenol, but juvenile and adult zebrafish have a more effective (high induction levels). The use of zebrafish juveniles, larvae and embryos offers an alternative stage to detect EDCs.",
        "keywords": [
            "developmental stages",
            "endocrine disruption",
            "gene expression",
            "zebrafish",
            "embryos",
            "control group",
            "gene transcription"
        ],
        "authors": [
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Rujia Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Comparative biochemistry and physiology. Toxicology & pharmacology : CBP",
        "year": 2009
    },
    "ecYZlhV4": {
        "id": "ecYZlhV4",
        "title": "Offspring toxicity of silver nanoparticles to Arabidopsis thaliana flowering and floral development.",
        "abstract": "Many studies have considered silver nanoparticles (AgNPs) cytotoxicity to mammalian and human cell lines and plant growth. However, only few studies considered toxic effects of AgNPs on plant offspring, especially on flowering. Arabidopsis thaliana was treated with 12.5 mg/kg AgNPs employing parental-(P-AgNPs) and offspring-generation (O-AgNPs) exposure to study the effects of AgNPs on flowering and floral development. Exposure to P-AgNPs was found to significantly decrease petal and pollen viability and subsequently reduced pod production. The inhibition of A. thaliana vegetative growth caused by P-AgNPs exposure was transferred to offspring and even became more severe in the O-AgNPs group. Further, the transcription of genes related to flowering and floral organ development in P-AgNPs and O-Con plants was downregulated by approximately 10-40% compared to the transcription in P-Con plants and showed a stronger decrease in the O-AgNPs group to 30-50% of that in the P-AgNPs group. This resulted in a delay in flowering of 4, 3 and 8 days in P-AgNPs, O-Con and O-AgNPs plants, respectively. Our research shows that the negative effects on floral development can be transferred to the offspring in A. thaliana, which may have significant implications with regard to the risks posed by NPs to food safety and security.",
        "keywords": [
            "Arabidopsis thaliana",
            "Floral organ",
            "Flowering time",
            "Offspring toxicity",
            "Silver nanoparticles"
        ],
        "authors": [
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, RA Leiden 2300, the Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, the Netherlands."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Nuohan Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Journal of hazardous materials",
        "year": 2019
    },
    "D0RVtlis": {
        "id": "D0RVtlis",
        "title": "The impact of germination on the characteristics of brown rice flour and starch.",
        "abstract": "In recent years, germinated brown rice as a functional food has received great attention with its improved sensory and nutritional properties. Particularly of interest are the high levels of γ-amino butyric acid (GABA) which can be obtained during germination. However, more studies are needed to fully understand the effect of germination on the physicochemical properties of brown rice.Germination altered the chemical composition of brown rice, resulting in an increase in reducing sugar and ash content, and a reduction in amylose. Solubility, paste viscosity, transition temperatures (T(o) , T(p) and T(c) ) and percentage of retrogradation (%Retrogradation) were decreased, while swelling power and turbidity were significantly increased. Scanning electron micrographs indicated that starch granules from germinated brown rice became smaller and less homogeneous. Moreover, germination shortened the chain length of amylopectin and amylose molecules.This investigation provides information on changes in the characteristics of rice flour and rice starch during germination, leading to a better understanding on the chemistry of brown rice germination.",
        "keywords": [
            "physicochemical properties",
            "amylopectin fine structure",
            "in vitro digestibility",
            "germinated brown rice",
            "germination"
        ],
        "authors": [
            {
                "name": "Jie Xu",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Xiaona Guo",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "Journal of the science of food and agriculture",
        "year": 2012
    },
    "n0bK7xgx": {
        "id": "n0bK7xgx",
        "title": "Extraction, purification and identification of antifreeze proteins from cold acclimated malting barley (Hordeum vulgare L.).",
        "abstract": "Antifreeze proteins from cold-acclimated malting barley were extracted by infiltration-centrifugation. The infiltration time was optimised, and its extraction effect was evaluated. The effect of cold acclimation on the accumulation of barley antifreeze proteins (BaAFPs) was assessed by comparing the thermal hysteresis activities (THA) of proteins extracted from both cold acclimated and non-cold acclimated barley grain. Ultra-filtration, ammonium precipitation and column chromatography were used successively to purify the BaAFPs, and MALDI-TOF-MS/MS was used for protein identification. The results showed that infiltration-centrifugation was more targeted than the traditional method, and 10h was the optimal infiltration time. THA was observed only after cold acclimation implied that AFPs only began to accumulate after cold acclimation. After purification, BaAFP-I was obtained at an electrophoresis level and its THA was 1.04°C (18.0 mg ml(-1)). The mass fingerprinting and sequencing results indicated the homology of the BaAFP-I to alpha-amylase inhibitor BDAI-1 (Hordeum vulgare).",
        "keywords": [
            "2-mercaptoethanol (pubchem cid: 1567)",
            "ammonium sulphate (pubchem cid: 6097028)",
            "antifreeze proteins",
            "barley (hordeum vulgare l.)",
            "bromophenol blue (pubchem cid: 8272)",
            "cold acclimate",
            "disodium phosphate dodecahydrate (pubchem cid: 61456)",
            "glycerol (pubchem cid: 753)",
            "hydrochloric acid (pubchem cid: 313)",
            "identification",
            "infiltration–centrifugation",
            "purification",
            "sodium chloride (pubchem cid: 5234)",
            "sodium dihydrogen phosphate (pubchem cid: 23673460)",
            "tromethamine (pubchem cid: 6503)"
        ],
        "authors": [
            {
                "name": "Xiangli Ding",
                "org": "State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            },
            {
                "name": "Haiying Chen",
                "org": "Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment &amp; Technology &amp; School of Mechanical Engineering, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology &amp; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, PR China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2015
    },
    "B4QY1VOx": {
        "id": "B4QY1VOx",
        "title": "Copper toxicity to Phaeodactylum tricornutum: a survey of the sensitivity of various toxicity endpoints at the physiological, biochemical, molecular and structural levels.",
        "abstract": "Copper (Cu) is one of the most toxic metals in phytoplankton but the toxicity mechanisms of this metal are still not fully understood. This study examines the toxicity targets of Cu in the modeled marine diatom, Phaeodactylum tricornutum, at the physiological (cell division, DNA cell cycle), biochemical [pigments synthesis, reactive oxygen species (ROS) and malondialdehyde (MDA)], structural (subcellular observation by flow cytometry) and molecular (transcription of several metalloprotein genes) level. Cu toxicity was detectable at all these levels after 48 h of exposure to a parts per thousand yen20 mu M total initial added Cu. The order of sensitivity of all the studied Cu toxicity endpoints was: G2/M phase > MDA > metalloproteins RNA of the photosynthetic electron transport chain (ETC) > metalloproteins RNA of the respiratory chains > G0/G1 phase > pigments a parts per thousand S phase > propidium iodide > estimated cell yield > ROS. The relatively sensitive decrease of the transcription of metalloproteins RNA of the ETC in response to Cu exposure, if associated to an effective decrease in the expression of the proteins composing the ETC, may help to initially mitigate the ROS-mediated toxic effects of Cu in P. tricornutum. However, this cellular response to Cu was only transitory and the transcription of virtually all genes involved in redox electron transfer chains was up-regulated within an interval of 2 days. This study brings new insights into the cellular mechanisms of Cu toxicity by documenting the sensitivity and kinetics of multiple Cu-cellular targets in one marine alga.",
        "keywords": [
            "Phaeodactylum tricornutum",
            "Copper toxicity",
            "Electron transfer chains",
            "Gene transcript"
        ],
        "authors": [
            {
                "name": "Yong Wei",
                "org": "Zhejiang Univ Technol, Dept Food Sci & Technol, Hangzhou 310032, Zhejiang, Peoples R China"
            },
            {
                "name": "Na Zhu",
                "org": "Zhejiang Univ Technol, Coll Biol & Environm Engn, Hangzhou 310032, Zhejiang, Peoples R China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Univ Laval, Quebec Ocean & Takuvik Joint Int Res Unit, Quebec City, PQ, Canada"
            },
            {
                "name": "Jiaying Wang",
                "org": "Zhejiang Univ Technol, Dept Food Sci & Technol, Hangzhou 310032, Zhejiang, Peoples R China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang Univ Technol, Dept Food Sci & Technol, Hangzhou 310032, Zhejiang, Peoples R China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang Univ Technol, Coll Biol & Environm Engn, Hangzhou 310032, Zhejiang, Peoples R China"
            }
        ],
        "venue": "BIOMETALS",
        "year": 2014
    },
    "Uq67T0AO": {
        "id": "Uq67T0AO",
        "title": "Microbial diversity analysis in rotating drum biofilter for nitric oxide denitrifying removal",
        "abstract": "PCR-DGGE was applied to analyze the microbial communities in rotating drum biofilter (RDB) for nitric oxide denitrifying removal under anaerobic conditions. The 16S rRNA genes (V3 region) were amplified with two universal primers (338F-GC and 518R). These amplified DNA fragments were separated by parallel DGGE. The DGGE profiles of biofilm samples from different sections of RDB are similar and about sixteen types of microorganisms are identified in the biofilm samples. These results show that microbial diversity of RDB firstly increases but then decreases with the addition of Cu II (EDTA) and the increase of NO removal efficiency. However, the change of microbial community is not significant during the process. Eight major bands of 16S rRNA genes fragments from DGGE profiles of biofilm samples were further eluted from gel, re-amplified, cloned and sequenced. The sequences of these fragments were compared with the database in GeneBank (NCBI). The gene analysis of 16S rRNA showed that the major populations are Cytopahga-Flexibacteria-Bacteroides (CFB) group Bacteroides, beta -Proteobacterium, gamma-Proteobacterium and Clostridium sp.. In addition, denitrification is related with band G-5, G-6 and G-8. G-5 is affiliated with gamma-Proteobacterium. Both G-6 and G-8 are affiliated with beta-Proteobacterium.",
        "keywords": [
            "16S ribosome RNA (16S rRNA)",
            "Denaturing gradient gel electrophoresis (DGGE)",
            "Microbial diversity",
            "Rotating drum biofilter",
            "Sequence"
        ],
        "authors": [
            {
                "name": "Jun Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhi-ye Wang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yi-feng Jiang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Hai-feng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Hao-lei Sha",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Jian-meng Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue / [bian ji, Zhongguo ke xue yuan huan jing ke xue wei yuan hui \"Huan jing ke xue\" bian ji wei yuan hui.]",
        "year": 2008
    },
    "dcP5vNPG": {
        "id": "dcP5vNPG",
        "title": "Effects of Soil Residual Plastic Film on Soil Microbial Community Structure and Fertility",
        "abstract": "Plastic films have previously displayed tremendous potential to increase water use efficiency in farmland and the yield of cash crops; however, long-term use of plastic film in soils can influence soil physiological and biochemical characteristics and change its biota. The present study aimed to investigate the effects of residual plastic film pollution on soil microbe community structure and fertility in Xinjiang province, China. Residual plastic film-contaminated soil and non-contaminated soil in Xinjiang farmland were selected for this study. The results indicated that residual plastic film pollution changed the structure of the soil biological community by significantly decreasing and increasing the abundance of  and , respectively; further, the pollution decreased soil organic matter and inorganic nitrogen content by downregulating microbial genes related to soil carbon and nitrogen cycles and decreasing related enzymatic activities. The present results indicated that long-term residual plastic film exposure (more than 10 years) in farmland significantly decreases soil fertility and alters the microbial community structure.",
        "keywords": [
            "Plastic film",
            "Microbial community structure",
            "16S rDNA sequencing",
            "Soil fertility"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation,Chinese Academy of Sciences,Urumqi,People’s Republic of ChinaCollege of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Guangfu Liu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Benben Du",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Water, Air, & Soil Pollution",
        "year": 2018
    },
    "lL8jsJgX": {
        "id": "lL8jsJgX",
        "title": "An efficient identity-based secret key management scheme for MANETs",
        "abstract": "",
        "keywords": [
            "key management",
            "mobile ad hoc networks",
            "security"
        ],
        "authors": [
            {
                "name": "yong zhang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "The Journal of China Universities of Posts and Telecommunications",
        "year": 2012
    },
    "pTjtfeGS": {
        "id": "pTjtfeGS",
        "title": "Inhibitory effects of atrazine on Chlorella vulgaris as assessed by real-time polymerase chain reaction.",
        "abstract": "Atrazine, a highly toxic herbicide, is frequently detected in surface water because of its heavy application. Algae are among the aquatic organisms most susceptible to atrazine pollution in water. In the present study, the aquatic alga Chlorella vulgaris Beijerinck was chosen to assess the acute toxicity of atrazine (48-96 h) in terms of gene transcription and physiological changes. A real-time polymerase chain reaction (PCR) assay was used to quantify transcript levels of three photosystem genes in C. vulgaris. The diel patterns for regulation of the psaB (photosystem I reaction center protein subunit B), psbC (an integral membrane protein component of photosystem II), and rbcL (large subunit of ribulose-1,5-bisphosphate carboxylase oxygenase) gene transcripts were successfully quantified. Results showed that atrazine reduced the transcript abundances of three target genes and that the abundances decreased with increasing atrazine concentration. The determined smallest transcript levels of psaB, psbC, and rbcL, which occurred at the highest atrazine concentration tested (400 mug/L), were only 34.6, 34.6, and 8.1%, respectively, of the control sample value. Exposure to atrazine increased the level of malondialdehyde by 1.74-fold (the highest value) in C. vulgaris, suggesting potential oxidative damage to the alga. The activities of antioxidation enzymes (e.g., superoxide dismutase, peroxidase, and catalase) also increased markedly in the presence of atrazine, with maximum increases of 1.82-, 1.59-, and 2.31-fold, respectively. These elevated activities may help to alleviate the oxidative damage. Our results demonstrate that atrazine is highly toxic to this alga and that real-time PCR is an efficient technique for assessing the toxicity of xenobiotic compounds in algae.",
        "keywords": [
            "atrazine",
            "chlorella vulgaris",
            "enzyme assay",
            "real-time polymerase chain reaction",
            "real time polymerase chain reaction"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "G Daniel Sheng",
                "org": ""
            },
            {
                "name": "Weiping Liu",
                "org": ""
            },
            {
                "name": "Yingcong Lu",
                "org": ""
            },
            {
                "name": "Zhenghai Liu",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Environmental toxicology and chemistry / SETAC",
        "year": 2008
    },
    "0Y6xeWyN": {
        "id": "0Y6xeWyN",
        "title": "Physiological and Molecular Response of  to CuO Nanoparticle (nCuO) Exposure",
        "abstract": "The widespread application of copper oxide nanoparticles (nCuO) results in ecological risk when nanoparticles enter the environment. This study clarifies the mechanism of nCuO toxicity in  seedlings via comparison with copper (Cu) ion bioeffects. Under the same culture conditions, Cu ion exposure exerted a stronger inhibitory effect on plant fresh weight and growth and caused stronger oxidative disruption (measured by malondialdehyde, MDA) than nCuO exposure. The Cu ions also showed a stronger induction effect than did nCuO on the activity of antioxidant enzymes and the transcription of antioxidant-related genes. Dissolved Cu ions contributed a minority of the toxicity of nCuO, implying that nCuO itself showed relative strong phytotoxicity. The work presented here will help increase our understanding of the toxicity of metal nanoparticles in plants.",
        "keywords": [
            "Copper oxide nanoparticle (nCuO)",
            "Arabidopsis thaliana",
            "Antioxidant gene",
            "Phytotoxicity"
        ],
        "authors": [
            {
                "name": "Mingjing Ke",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Hailiqieguli Gumai",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Junjie Xu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of ChinaXinjiang Key Laboratory of Environmental Pollution and Bioremediation,Chinese Academy of Sciences,Urumqi,People’s Republic of China"
            }
        ],
        "venue": "Bulletin of Environmental Contamination and Toxicology",
        "year": 2017
    },
    "S36yUHFX": {
        "id": "S36yUHFX",
        "title": "Enantioselective effects of imazethapyr residues on Arabidopsis thaliana metabolic profile and phyllosphere microbial communities.",
        "abstract": "Imazethapyr (IM) is a widely used acetolactate synthase-inhibiting chiral herbicide. It has long-term residuals that may be absorbed by the human body through the edible parts of plants, such as vegetable leaves or fruits. Here, we selected a model plant, Arabidopsis thaliana, to determine the effects of R-IM and S-IM on its leaf structure, photosynthetic efficiency, and metabolites, as well as the structures of microorganisms in the phyllosphere, after 7 days of exposure. Our results indicated enantiomeric differences in plant growth between R-IM and S-IM; 133 µg/kg R-IM showed heavier inhibition of photosynthetic efficiency and greater changes to subcellular structure than S-IM. R-IM and S-IM also had different effects on metabolism and leaf microorganisms. S-IM mainly increased lipid compounds and decreased amino acids, while R-IM increased sugar accumulation. The relative abundance of Moraxellaceae human pathogenic bacteria was increased by R-IM treatment, indicating that R-IM treatment may increase leaf surface pathogenic bacteria. Our research provides a new perspective for evaluating the harmfulness of pesticide residues in soil, phyllosphere microbiome changes via the regulation of plant metabolism, and induced pathogenic bacterial accumulation risks.",
        "keywords": [
            "Arabidopsis thaliana",
            "Chiral herbicides",
            "Enantioselectivity",
            "Leaf metabolism",
            "Phyllosphere microorganism"
        ],
        "authors": [
            {
                "name": "Qianqiu Zhao",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Wanyue Liu",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Wenting Yuan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Journal of environmental sciences (China)",
        "year": 2020
    },
    "MasOnDWE": {
        "id": "MasOnDWE",
        "title": "Effect of barley antifreeze protein on thermal properties and water state of dough during freezing and freeze-thaw cycles",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiangli ding",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            },
            {
                "name": "jianhui xiao",
                "org": ""
            }
        ],
        "venue": "Food Hydrocolloids",
        "year": 2015
    },
    "PYWVBESB": {
        "id": "PYWVBESB",
        "title": "Pitfalls in identity based encryption using an elliptic curve combined public key.",
        "abstract": "Recently, Zhang et al. proposed two encryption schemes using an elliptic curve combined public key. We show, via the trick of using a linear equation system, that both proposals are vulnerable to key recovery attack, and thus in the present form must be considered as insecure. We simulate our trick on a common personal laptop and always get the results at a sub-second level. © 2012 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "combined public key",
            "key privacy",
            "public key encryption"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            }
        ],
        "venue": "Appl. Math. Lett.",
        "year": 2012
    },
    "b04kSZsZ": {
        "id": "b04kSZsZ",
        "title": "A newly isolated and rapid denitrifier Pseudomonas citronellolis WXP-4: difference in N 2 O emissions under aerobic and anaerobic conditions.",
        "abstract": "A novel and efficient facultative anaerobic denitrifying bacterium was isolated and identified as Pseudomonas citronellolis WXP-4. The strain WXP-4 could achieve 100% nitrate and nitrite removal efficiency utilizing sodium succinate as a carbon source, C/N ratio 7, pH 7.0, and temperature 40 °C under both aerobic and anaerobic conditions. The bacterium could tolerate a wide range of NO3−–N concentrations from 100 to 1000 mg/L with a maximum nitrogen removal rate of 32.05 mg/(L h). An interesting phenomenon was found that no N2O emission occurred during the denitrifying process under anaerobic conditions, while there was 0.06 mg/L under aerobic conditions. This phenomenon had been confirmed by fluorescence quantitative PCR and the results showed that the relative abundance of nosZ gene increased by 17-fold based on the ratio of anaerobic to aerobic, and thus, nosZ gene could encode more nitrous oxide reductase to accelerate the conversion of N2O under anaerobic conditions. Moreover, the narG, nirK, and norB genes were also identified in the denitrifying pathway of the strain WXP-4. This investigation has demonstrated enormous potential for the future application in wastewater treatment systems.",
        "keywords": [
            "\n                Pseudomonas citronellolis\n              ",
            " Nitrogen removal",
            " Metabolic pathway",
            " Denitrification genes",
            " Nitrous oxide",
            " Fluorescence quantitative PCR"
        ],
        "authors": [
            {
                "name": "Xiaoping Wang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Yankai Duo",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Jinjia He",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Jiachao Yao",
                "org": "College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Dzmitry Hrynsphan",
                "org": "Research Institute of Physical and Chemical Problems, Blearusian State University, Minsk, Belarus"
            },
            {
                "name": "Savitskaya Tatsiana",
                "org": "Research Institute of Physical and Chemical Problems, Blearusian State University, Minsk, Belarus"
            },
            {
                "name": "Jun Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou, People’s Republic of China"
            }
        ],
        "venue": "Bioprocess and Biosystems Engineering",
        "year": 2020
    },
    "unLGGMJm": {
        "id": "unLGGMJm",
        "title": "Extraction of Oat ( L.) Antifreeze Proteins and Evaluation of Their Effects on Frozen Dough and Steamed Bread",
        "abstract": "In this study, vacuum infiltration-centrifugation of cold-induced oats at −18 °C was adopted in the extraction of oat antifreeze proteins (AFPs), and the effects of the oat AFPs on the physicochemical, rheological, and fermentation properties of frozen dough and the textural characteristics of steamed bread were investigated. Supplementation with oat AFPs lowered the freezable water content of the dough, resulting in some beneficial effects on final steamed bread. The rheological properties of the oat AFP group showed a greater fermentation capacity than did the control group (without oat AFP). A scanning electron microscopic analysis showed that supplementation with oat AFPs could protect the gluten matrix from disruption, thus resulting in superior textural properties in the steamed bread. In conclusion, oat AFPs could be used as a beneficial additive to frozen dough.",
        "keywords": [
            "Oat (",
            "Avena sativa",
            "L.)",
            "Vacuum infiltration-centrifugation",
            "Antifreeze proteins",
            "Frozen dough",
            "Steamed bread",
            "Properties"
        ],
        "authors": [
            {
                "name": "Yanjie Zhang",
                "org": "State Key laboratory of Food Science and Technology,Jiangnan University,Wuxi,ChinaSchool of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "State Key laboratory of Food Science and Technology,Jiangnan University,Wuxi,ChinaSchool of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Li Wang",
                "org": "State Key laboratory of Food Science and Technology,Jiangnan University,Wuxi,ChinaSchool of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key laboratory of Food Science and Technology,Jiangnan University,Wuxi,ChinaSchool of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key laboratory of Food Science and Technology,Jiangnan University,Wuxi,ChinaSchool of Food Science and Technology,Jiangnan University,Wuxi,China"
            }
        ],
        "venue": "Food and Bioprocess Technology",
        "year": 2015
    },
    "MGtytqJs": {
        "id": "MGtytqJs",
        "title": "Dynamic address configuration based on threshold in mobile Ad hoc network",
        "abstract": "Due to the vicious actions of malicious nodes in an adversarial network,address auto-configuration couldn’t be carried out with effect. To thwart corresponding security attacks about address auto-configuration in MANETs,this paper presented a dynamic address configuration based on threshold in an adversarial MANETs,referred to Threshconf. Threshconf with access control constructed by using threshold signature could prevent against correlative networks and guarantee the protocol could be executed effectively in hostile networks. Finally,also discussed the performance and security of Threshconf.",
        "keywords": [
            "access control",
            "threshold signature",
            "Threshconf",
            "malicious node",
            "dynamic address configuration",
            "mobile Ad hoc network"
        ],
        "authors": [
            {
                "name": "YI Shuang-feng",
                "org": " Dept. of Computer Science & Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": " Dept. of Computer Science & Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "ZHOU Yuan",
                "org": " National Computer Network Emergency Response Technical Team/Coordination Center of China,Beijing ,China"
            }
        ],
        "venue": "Application Research of Computers",
        "year": 2010
    },
    "M0Krwh6N": {
        "id": "M0Krwh6N",
        "title": "Enhanced terrestrial carbon uptake in the Northern High Latitudes in the 21st century from the Coupled Carbon Cycle Climate Model Intercomparison Project model projections",
        "abstract": "",
        "keywords": [
            "carbon cycle",
            "co2",
            "climate model",
            "climate change"
        ],
        "authors": [
            {
                "name": "HAIFENG QIAN",
                "org": ""
            },
            {
                "name": "RENU JOSEPH",
                "org": ""
            },
            {
                "name": "NING ZENG",
                "org": ""
            }
        ],
        "venue": "Global Change Biology",
        "year": 2010
    },
    "f4wK5wmY": {
        "id": "f4wK5wmY",
        "title": "Signcryption KEM/tag-KEM, revisited: Signcryption KEM/tag-KEM, revisited",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yu yu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yuan zhou",
                "org": ""
            },
            {
                "name": "xiangxue li",
                "org": ""
            },
            {
                "name": "jian weng",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2015
    },
    "jXACb96S": {
        "id": "jXACb96S",
        "title": "New proxy blind multi-signature scheme",
        "abstract": "With proxy multi-signature,many original signers can delegate their signing power to a proxy signer in such a way that the proxy signer can sign any message on behalf of them.In blind signature,the signer cannot make a linkage between the blind signature and the identity of the requester.Therefore,they are easily applied in electronic commerce.Based on Schnorr signature scheme,a new proxy blind multi-signature scheme was proposed.One proxy signer can generate a proxy blind multi-signature on behalf of many original signers.This scheme satisfies the security properties of both the blind signature scheme and the proxy multi-signature scheme.It has advantages such as low computation load,high efficiency and security,and that the length of signature does not increase when the new original signers join in.",
        "keywords": [
            "proxy blind multi-signature",
            "blind signature",
            "proxy signature",
            "proxy blind signature"
        ],
        "authors": [
            {
                "name": "HU Zhen-peng",
                "org": "Department of Computer Science,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science,East China Normal University,Shanghai ,China"
            },
            {
                "name": "LI Zhi-bin",
                "org": "Department of Computer Science,East China Normal University,Shanghai ,China"
            }
        ],
        "venue": "Journal of Computer Applications",
        "year": 2007
    },
    "XXFbrZPl": {
        "id": "XXFbrZPl",
        "title": "Braid-based bit commitment protocol",
        "abstract": "With recent advances of quantum computation, new threats have closed in upon to the classical public key cryptosystems. In order to build more secure bit commitment schemes, this paper gave a survey of the new coming braid-based cryptography and then brought forward the first braid-based bit commitment protocol. The security proof manifests that the proposed protocol is computationally binding and information-theoretically hiding. Furthermore, the proposed protocol is also invulnerable to currently known quantum attacks.",
        "keywords": [
            "Bit commitment",
            "Braid-based cryptography",
            "Quantum attack"
        ],
        "authors": [
            {
                "name": "Licheng Wang",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Feng Cao",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Journal of Shanghai Jiaotong University (Science)",
        "year": 2006
    },
    "PSsbRxUx": {
        "id": "PSsbRxUx",
        "title": "Practical round-optimal blind signatures without random oracles or non-interactive zero-knowledge proofs: Practical round-optimal blind signatures",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yuan zhou",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2011
    },
    "qpPb0vmU": {
        "id": "qpPb0vmU",
        "title": "Validation of GOES-16 ABI infrared spatial response uniformity.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "John Van Naarden",
                "org": ""
            },
            {
                "name": "Michael Ramirez",
                "org": ""
            },
            {
                "name": "Dan Lindsey",
                "org": ""
            },
            {
                "name": "Chad Gravelle",
                "org": ""
            },
            {
                "name": "Mathew M. Gunshor",
                "org": ""
            },
            {
                "name": "Timothy J. Schmit",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Zhipeng Wang",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            },
            {
                "name": "Bob Iacovazzi",
                "org": ""
            },
            {
                "name": "Vladimir Kondratovich",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2018
    },
    "ivF4XVIT": {
        "id": "ivF4XVIT",
        "title": "Rhizosphere microorganisms can influence the timing of plant flowering.",
        "abstract": "We document a novel metabolic network in which soil microbiota influenced plant flowering time, thus shedding light on the key role of soil microbiota on plant functioning. This opens up multiple opportunities for application, from helping to mitigate some of the effects of climate change and environmental stress on plants (e.g. abnormal temperature variation, drought, salinity) to manipulating plant characteristics using microbial inocula to increase crop potential.",
        "keywords": [
            "Arabidopsis",
            "Flowering time",
            "Indole acetic acid",
            "Microbiota",
            "Nitrogen",
            "Rhizosphere",
            "Root exudate"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, G1VOA6, Canada."
            },
            {
                "name": "Yujian Jin",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Michael Gillings",
                "org": "Department of Biological Sciences, Macquarie University, Sydney, NSW, 2109, Australia."
            },
            {
                "name": "Josep Peñuelas",
                "org": "CREAF, Cerdanyola del Vallès, Barcelona, Catalonia, Spain."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China. hfqian@zjut.edu.cn."
            },
            {
                "name": "Yong-Guan Zhu",
                "org": "State Key Lab of Urban and Regional Ecology, Research Center for Ecoenvironmental Sciences, Chinese Academy of Sciences, Beijing, 100085, People's Republic of China. ygzhu@iue.ac.cn."
            }
        ],
        "venue": "Microbiome",
        "year": 2018
    },
    "nZwVey1K": {
        "id": "nZwVey1K",
        "title": "Blind signature without random oracles",
        "abstract": "In recent years, the studies of blind signatures achieved a lot of results, but there still are many problems. Boneh and Boyen gave a new signature, derived the blind signature scheme from their idea. This paper first gave a blind signature without random oracles, with this property, the scheme was secure in standard model. Then, used common reference string to do non-interactive zero knowledge proof, made the blind signature into only two moves to achieve round optimal, and the concurrency operation of blind signature could be reach by this. For the algorithm is simple and not complicated, the blind signature is more efficient than the existing secure blind signature schemes,so save transmission bandwidth and improves transfer efficiency.",
        "keywords": [
            "blind signature",
            "blindness",
            "random oracle",
            "unforgeability"
        ],
        "authors": [
            {
                "name": "WANG Jing-ran",
                "org": "Dept. of Computer Science, East China Normal University, Shanghai , China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Dept. of Computer Science, East China Normal University, Shanghai , China"
            }
        ],
        "venue": "Application Research of Computers",
        "year": 2010
    },
    "GZiCj7LR": {
        "id": "GZiCj7LR",
        "title": "Optimal Power Control and Link Selection Policy for Buffer-Aided Two-Hop Secure Communications.",
        "abstract": "In this paper, secure communication over a buffer-aided two-hop communication link, in which a source sends data to a destination with the aid of a trusted half-duplex relay node in the presence of a passive eavesdropper, is studied. It is assumed that there is no direct link between the source and the destination, and the buffer-aided relay forwards the information to the destination by employing the decode-and-forward (DF) scheme. Both the source and the relay transmissions are assumed to be vulnerable to the eavesdropper. The perfect channel side information (CSI) of the network is assumed to be available at the source and the relay. Initially, conventional relaying protocols where equal partition of the time for the reception and transmission of the relay is considered. Then, the optimal time fraction with the optimal power control policy that maximizes the secrecy throughput is identified. Subsequently, the optimal joint link selection and power control policy that maximizes the secrecy throughput is derived. Numerical results demonstrate that the joint link selection and power control scheme can significantly improve the achievable secrecy throughput of the buffer-aided two-hop communication system.",
        "keywords": "",
        "authors": [
            {
                "name": "Jing Wan",
                "org": "School of Information Science & Technology, East China Normal University, Shanghai, China#TAB#"
            },
            {
                "name": "Deli Qiao",
                "org": "School of Information Science & Technology, East China Normal University, Shanghai, China#TAB#"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Computer Science and Software Engineering, East China Normal University, Shanghai, China#TAB#"
            }
        ],
        "venue": "ICNC",
        "year": 2018
    },
    "X4K61OaZ": {
        "id": "X4K61OaZ",
        "title": "Ecotoxicological Effects of Fungicides Azoxystrobin and Pyraclostrobin on Freshwater Aquatic Bacterial Communities.",
        "abstract": "Extensive use of the fungicides azoxystrobin (AZ) and pyraclostrobin (PYR) can have negative effects on aquatic environments, but comprehensive studies on their effect on aquatic microbial communities are still lacking. We found that AZ and PYR could both inhibit the growth of Chlorella vulgaris, but PYR also inhibited Microcystis aeruginosa more strongly than did AZ. High-throughput sequencing analysis showed that AZ promoted the growth of Cyanobacteria in microcosms, and both PYR and AZ disturbed the ecological balance in the aquatic bacterial community and created distinct ecological risks. Our study suggests that the ecological risk of fungicides is complex, and fungicide use should be better managed to reduce potential risks to the environment.",
        "keywords": [
            "Strobilurin",
            " Microalgae",
            " Microbial community",
            " Cyanobacterial bloom"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China"
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China"
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China"
            }
        ],
        "venue": "Bulletin of Environmental Contamination and Toxicology",
        "year": 2019
    },
    "PbNogyj7": {
        "id": "PbNogyj7",
        "title": "The effect of glufosinate on nitrogen assimilation at the physiological, biochemical and molecular levels in  ",
        "abstract": "This study investigated the effects of glufosinate, a widely used herbicide, on the marine diatom  through short-term toxicity tests at the physiological and gene transcriptional levels. Glufosinate (4 mg L) decreased the amount of pigments but increased reactive oxygen species (ROS) and malondialdehyde levels. As a glutamine synthetase (GS) inhibitor, glufosinate affected the transcripts and activities of key enzymes related to nitrogen assimilation. Transcript levels of  and nitrate reductase () in  decreased to only 57 and 26 % of the control. However, transcript levels of nitrate transporter () and the small subunit of glutamate synthase () were 1.79 and 1.76 times higher than that of the control. The activities of NRT, GS and GOGAT were consistent with gene expression except for NR, which was regulated mainly by post-translational modification. Furthermore, the results of electron microscopy showed that chloroplast structure was disrupted in response to glufosinate exposure. These results demonstrated that glufosinate first disturbed nitrogen metabolism and caused a ROS burst, which disrupted chloroplast ultrastructure. Ultimately, the growth of  was greatly inhibited by glufosinate.",
        "keywords": [
            "Phaeodactylum tricornutum",
            "Glufosinate",
            "Nitrogen assimilation",
            "Electron microscopy",
            "Real-time PCR"
        ],
        "authors": [
            {
                "name": "Jun Xie",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiaocui Bai",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Yali Li",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Chongchong Sun",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of ChinaCollege of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Ecotoxicology",
        "year": 2014
    },
    "KE7sO5dI": {
        "id": "KE7sO5dI",
        "title": "Anonymous password-based key exchange with low resources consumption and better user-friendliness",
        "abstract": "Anonymous password authenticated key exchange (APAKE) protocols allow the server to authenticate its clients without revealing their identities. In this paper, we first construct a basic protocol SAPAKE by using the homomorphic encryption scheme and an auxiliary memory device. Compared with the previous ones, SAPAKE is more suitable for those privacy-sensitive applications (e.g., cloud computing) where reducing server payload and improving user experience are both essential. Furthermore, we refine SAPAKE by removing the use of the memory device to gain an enhanced extension SAPAKE+ without increasing the resources consumption. SAPAKE+ achieves better user-friendliness than SAPAKE while it requires publishing more public parameters. Both of our protocols are practical due to their low (computation and communication) resources consumption and better user-friendliness, and achieve provable security in the random oracle model. Copyright © 2012 John Wiley & Sons, Ltd.",
        "keywords": [
            "anonymous password-based key exchange",
            "anonymous password",
            "memory device",
            "basic protocol sapake",
            "cloud computing",
            "low resources consumption",
            "auxiliary memory device",
            "better user-friendliness",
            "enhanced extension",
            "john wiley",
            "resources consumption",
            "server payload",
            "password",
            "provable security",
            "key exchange",
            "smart card",
            "authentication"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Junqing Gong",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Yuan Zhou",
                "org": "Network Emergency Response Technical Team/Coordination Center, China"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2012
    },
    "VNt1P1z4": {
        "id": "VNt1P1z4",
        "title": "Random walks in a supply network",
        "abstract": "This paper presents a power grid analyzer based on a random walk technique. A linear-time algorithm is first demonstrated for DC analysis, and is then extended to perform transient analysis. The method has the desirable property of localizing computation, so that it shows massive benefits over conventional methods when only a small part of the grid is to be analyzed (for example, when the effects of small changes to the grid are to be examined). Even for the full analysis of the grid, experimental results show tat the method is faster than existing approaches and has an acceptable error margin. This method has been applied to test circuits of up to 2.3M nodes. For example, for a circuit with 70K nodes, the solution time for a single node was 0.42 sec and the complete solution was obtained in 17.6 sec.",
        "keywords": [
            "full analysis",
            "small part",
            "linear-time algorithm",
            "circuit analysis computing",
            "supply network",
            "localizing computation",
            "digital circuits",
            "small change",
            "complete solution",
            "0.42 sec",
            "dc analysis",
            "conventional method",
            "acceptable error margin",
            "random walk",
            "integrated circuit design",
            "17.6 sec",
            "transient analysers",
            "solution time",
            "circuit testing",
            "transient analysis",
            "power grid analyzer",
            "rc circuits",
            "capacitors",
            "algorithm design and analysis",
            "mesh generation",
            "intelligent networks"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "University of Minnesota, Minneapolis, MN"
            },
            {
                "name": "Sani R. Nassif",
                "org": "IBM Austin Research Labs, Austin, TX"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota, Minneapolis, MN"
            }
        ],
        "venue": "DAC",
        "year": 2003
    },
    "XVUYi2z3": {
        "id": "XVUYi2z3",
        "title": "L2-Nonexpansive Neural Networks.",
        "abstract": "  This paper proposes a class of well-conditioned neural networks in which a unit amount of change in the inputs causes at most a unit amount of change in the outputs or any of the internal layers. We develop the known methodology of controlling Lipschitz constants to realize its full potential in maximizing robustness, with a new regularization scheme for linear layers, new ways to adapt nonlinearities and a new loss function. With MNIST and CIFAR-10 classifiers, we demonstrate a number of advantages. Without needing any adversarial training, the proposed classifiers exceed the state of the art in robustness against white-box L2-bounded adversarial attacks. They generalize better than ordinary networks from noisy data with partially random labels. Their outputs are quantitatively meaningful and indicate levels of confidence and generalization, among other desirable properties. ",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Mark N. Wegman",
                "org": ""
            }
        ],
        "venue": "ICLR",
        "year": 2019
    },
    "ozWqL2N6": {
        "id": "ozWqL2N6",
        "title": "Multi-Authority Non-Monotonic KP-ABE With Cryptographic Reverse Firewall",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Bo Hong",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "IEEE Access",
        "year": 2019
    },
    "phRM1068": {
        "id": "phRM1068",
        "title": "Extraction of Oat (Avena sativa L.) Antifreeze Proteins and Evaluation of Their Effects on Frozen Dough and Steamed Bread",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yanjie zhang",
                "org": "jiangnan university"
            },
            {
                "name": "hui zhang",
                "org": "jiangnan university"
            },
            {
                "name": "li wang",
                "org": "jiangnan university"
            },
            {
                "name": "haifeng qian",
                "org": "jiangnan university"
            },
            {
                "name": "xiguang qi",
                "org": "jiangnan university"
            }
        ],
        "venue": "Food and Bioprocess Technology",
        "year": 2015
    },
    "JxF1E6lH": {
        "id": "JxF1E6lH",
        "title": "Evaluation of the Sensor Data Record from the nadir instruments of the Ozone Mapping Profiler Suite (OMPS)",
        "abstract": "",
        "keywords": [
            "calibration",
            "radiative transfer",
            "irradiation",
            "solar radiation",
            "stability",
            "data processing",
            "calibrating",
            "sensors",
            "spectral resolution",
            "remote sensing",
            "ozone"
        ],
        "authors": [
            {
                "name": "xiangqian wu",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "quanhua liu",
                "org": "university of maryland college park"
            },
            {
                "name": "jian zeng",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "michael grotenhuis",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "haifeng qian",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "m z caponi",
                "org": ""
            },
            {
                "name": "lawrence e flynn",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "glen jaross",
                "org": "goddard space flight center"
            },
            {
                "name": "bhaswar sen",
                "org": "grumman aircraft corporation"
            },
            {
                "name": "r buss",
                "org": ""
            },
            {
                "name": "william johnsen",
                "org": "raytheon"
            },
            {
                "name": "s janz",
                "org": "goddard space flight center"
            },
            {
                "name": "chunhui pan",
                "org": "university of maryland college park"
            },
            {
                "name": "jianguo niu",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "trevor beck",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "eric beach",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "wei yu",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "m k rama varma raja",
                "org": ""
            },
            {
                "name": "derek stuhmer",
                "org": "raytheon"
            },
            {
                "name": "daniel cumpton",
                "org": "raytheon"
            },
            {
                "name": "c owen",
                "org": "raytheon"
            },
            {
                "name": "wenhao li",
                "org": "grumman aircraft corporation"
            }
        ],
        "venue": "Journal of Geophysical Research",
        "year": 2014
    },
    "ByhV9eu2": {
        "id": "ByhV9eu2",
        "title": "Energy cost of intracellular metal and metalloid detoxification in wild-type eukaryotic phytoplankton",
        "abstract": "Microalgae use various cellular mechanisms to detoxify both non-essential and excess essential metals or metalloids. There exists however, a threshold in intracellular metal(loid) concentrations beyond which detoxification mechanisms are no longer effective and inhibition of cell division inevitably occurs. It is therefore important to determine whether the availability of energy in the cell could constrain metal(loid) detoxification capacity and to better define the thresholds beyond which a metal(loid) becomes toxic. To do this we performed the first extensive bioenergetics analysis of intracellular metal(loid) detoxification mechanisms (e.g., metal-binding peptides, polyphosphate granules, metal efflux, metal and metalloid reduction, metalloid methylation, enzymatic and non-enzymatic antioxidants) in wild-type eukaryotic phytoplankton based on the biochemical mechanisms of each detoxification strategy and on experimental measurements of detoxifying biomolecules in the literature. The results show that at the onset of metal(loid) toxicity to growth, all the detoxification strategies considered required only a small fraction of the total cellular energy available for growth indicating that intracellular detoxification ability in wild-type eukaryotic phytoplankton species is not constrained by the availability of cellular energy. The present study brings new insights into metal(loid) toxicity mechanisms and detoxification strategies in wild-type eukaryotic phytoplankton.",
        "keywords": "",
        "authors": [
            {
                "name": "Michel Lavoie",
                "org": "Québec-Océan and Unité Mixte Internationale Takuvik Ulaval-CNRS, Département de Biologie, Université Laval,Québec,Canada"
            },
            {
                "name": "John A. Raven",
                "org": "Division of Plant Science, University of Dundee at the James Hutton Institute, Invergowrie,Dundee DD2 5DA,UK"
            },
            {
                "name": "John A. Raven",
                "org": "Division of Plant Science, University of Dundee at the James Hutton Institute, Invergowrie,Dundee DD2 5DA,UK"
            },
            {
                "name": "Oliver A. H. Jones",
                "org": "Australian Centre for Research on Separation Science (ACROSS), School of Applied Sciences, RMIT University, GPO Box 2476,Melbourne,Australia"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology,Hangzhou 310032,P. R. China"
            }
        ],
        "venue": "Metallomics",
        "year": 2016
    },
    "nk3iYaxg": {
        "id": "nk3iYaxg",
        "title": "Trustworthy information: concepts and mechanisms",
        "abstract": "We used to treating information received (from recognized sources) as trustworthy, which is unfortunately not true because of attacks. The situation can get worse with the emerging shift of information sharing paradigm from \"need to know\" to \"need to share.\" In order to help information consumers make the \"best\" decision possible, it is imperative to formulate concepts, models, frameworks, architectures, and mechanisms to facilitate information trustworthiness management in distributed and decentralized environment. In this paper we initiate a study in this direction by proposing an abstraction called information networks as well as two supporting mechanisms called provenance digital signatures and optimal security hardening of information network.",
        "keywords": [
            "provenance digital signature",
            "information trustworthiness management",
            "trustworthy information",
            "decentralized environment",
            "optimal security",
            "information sharing paradigm",
            "information consumer",
            "information network",
            "supporting mechanism",
            "digital signature"
        ],
        "authors": [
            {
                "name": "Shouhuai Xu",
                "org": "University of Texas at San Antonio"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University"
            },
            {
                "name": "Fengying Wang",
                "org": "Shandong University of Technology"
            },
            {
                "name": "Zhenxin Zhan",
                "org": "University of Texas at San Antonio"
            },
            {
                "name": "Elisa Bertino",
                "org": "Purdue University"
            },
            {
                "name": "Ravi Sandhu",
                "org": "University of Texas at San Antonio"
            }
        ],
        "venue": "WAIM",
        "year": 2010
    },
    "gI8YiYXz": {
        "id": "gI8YiYXz",
        "title": "Impact of 1998-2002 midlatitude drought and warming on terrestrial ecosystem and the global carbon cycle: DROUGHT AND CO2ANOMALIES",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Ning Zeng",
                "org": "Department of Atmospheric and Oceanic Science and Earth System Science Interdisciplinary Center; University of Maryland; College Park Maryland USA"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Atmospheric and Oceanic Science and Earth System Science Interdisciplinary Center; University of Maryland; College Park Maryland USA"
            },
            {
                "name": "C. Roedenbeck",
                "org": "Max-Planck-Institute for Biogeochemistry; Jena Germany"
            },
            {
                "name": "Martin Heimann",
                "org": "Max-Planck-Institute for Biogeochemistry; Jena Germany"
            }
        ],
        "venue": "Geophysical Research Letters",
        "year": 2005
    },
    "u3ZS4NOO": {
        "id": "u3ZS4NOO",
        "title": "Stochastic and hybrid linear equation solvers and their applications in vlsi design automation",
        "abstract": "This thesis presents two new linear equation solvers, and investigates their applications in VLSI design automation. Both solvers are derived in the context of a special class of large-scale sparse left-hand-side matrices that are commonly encountered in engineering applications, and techniques are presented that can potentially extend the theory to more general cases. The first is a stochastic solver that performs the computation by establishing the equivalence between linear equations and random walks. It has a desirable locality feature: a single unknown variable can be evaluated without solving the entire system. For complete solutions, it is competitive in applications with moderate accuracy requirement. The second is a hybrid solver: it combines the random walk technique and traditional iterative approaches. Given a set of linear equations, if the left-hand-side matrix satisfies certain conditions, it is proven that an incomplete triangular factorization can be obtained from random walks, and these factors can be used as a preconditioner in a traditional iterative linear equation solver to accelerate its convergence. In other words, the proposed hybrid solver is a stochastically preconditioned iterative solver. It is argued that our factor matrices have better quality, i.e., better accuracy-size tradeoffs, than preconditioners produced by existing incomplete factorization methods. Therefore the hybrid solver requires less computation than traditional preconditioned iterative solvers to solve a set of linear equations with the same error tolerance, and the advantage increases for larger and denser sets of linear equations. The application of these solvers on several problems in VLSI design is illustrated in this thesis, namely, power grid analysis, chip-level electrostatic discharge simulation, and quadratic placement. We not only demonstrate the efficiency of direct usage of the solvers, but also devise a set of application-specific techniques that are often based on indirect usage of the stochastic solver, due to the fact that the localized computation process of random walks carries meaningful information in various scenarios.",
        "keywords": [
            "random walk",
            "new linear equation solvers",
            "traditional preconditioned iterative solvers",
            "stochastically preconditioned iterative solver",
            "traditional iterative linear equation",
            "linear equation",
            "vlsi design automation",
            "proposed hybrid solver",
            "hybrid linear equation solvers",
            "stochastic solver",
            "hybrid solver",
            "random walk technique"
        ],
        "authors": [
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota"
            },
            {
                "name": "Haifeng Qian",
                "org": "University of Minnesota"
            }
        ],
        "venue": "Stochastic and hybrid linear equation solvers and their applications in vlsi design automation",
        "year": 2006
    },
    "PlzUBgO0": {
        "id": "PlzUBgO0",
        "title": "Inhibitory effects of polystyrene microplastics on caudal fin regeneration in zebrafish larvae.",
        "abstract": "Microplastic pollution is pervasive in aquatic environments, but the potential effects of microplastics on aquatic organisms are still under debate. Given that tissue damage is unavoidable in fish and the available data mostly concentrate on healthy fish, there is a large chance that the ecotoxicological risk of microplastic pollution is underrated. Therefore, in this study, the effects of microplastics on the regenerative capacity of injured fish were investigated using a zebrafish caudal fin regeneration model. After fin amputation at 72 h post fertilization, the larvae were exposed to polystyrene microplastics (0.1-10 mg/L) with diameters of 50 or 500 nm. Microplastic exposure significantly inhibited fin regeneration, both morphologically and functionally. Furthermore, the signaling networks that regulate fin regeneration, as well as reactive oxygen species signaling and the immune response, both of which are essential for tissue repair and regeneration, were altered. Transcriptomic analyses of the regenerating fin confirmed that genes related to fin regeneration were transcriptionally modulated in response to microplastic exposure and that metabolic pathways were also extensively involved. In conclusion, this study demonstrated for the first time that microplastic exposure could disrupt the regenerative capacity of fish and might eventually impair their fitness in the wild.",
        "keywords": [
            "Danio rerio",
            "Immune response",
            "Metabolic pathways",
            "Reactive oxygen species",
            "Tissue repair and regeneration"
        ],
        "authors": [
            {
                "name": "Linqi Gu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Li Tian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Gan Gao",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Shaohong Peng",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Jieyu Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Di Wu",
                "org": "Department of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, 211166, PR China."
            },
            {
                "name": "Jing Huang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Qing Hua",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Li Zhong",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: sunliwei@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2020
    },
    "Bb5DX6yG": {
        "id": "Bb5DX6yG",
        "title": "Bio-safety assessment of validamycin formulation on bacterial and fungal biomass in soil monitored by real-time PCR.",
        "abstract": "",
        "keywords": [
            "Rhizoctonia Solani",
            "Validamycin",
            "Biological Pesticide",
            "Actual Cell Number",
            "Target Gene Copy Number"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology College of Biological and Environmental Engineering Hangzhou Zhejiang 310032 China Hangzhou Zhejiang 310032 China"
            },
            {
                "name": "Baolan Hu",
                "org": "College of Environmental and Resource, Zhejiang University Ministry of Education Key Lab of Environment Remediation and Ecological Health Hangzhou Zhejiang 310029 China Hangzhou Zhejiang 310029 China"
            },
            {
                "name": "Dan Cao",
                "org": "Zhejiang University of Technology College of Biological and Environmental Engineering Hangzhou Zhejiang 310032 China Hangzhou Zhejiang 310032 China"
            },
            {
                "name": "Wei Chen",
                "org": "Zhejiang University of Technology College of Biological and Environmental Engineering Hangzhou Zhejiang 310032 China Hangzhou Zhejiang 310032 China"
            },
            {
                "name": "Xiaoyan Xu",
                "org": "Zhejiang University of Technology College of Biological and Environmental Engineering Hangzhou Zhejiang 310032 China Hangzhou Zhejiang 310032 China"
            },
            {
                "name": "Yingchong Lu",
                "org": "Zhejiang University of Technology College of Biological and Environmental Engineering Hangzhou Zhejiang 310032 China Hangzhou Zhejiang 310032 China"
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2007
    },
    "xTsiyC1b": {
        "id": "xTsiyC1b",
        "title": "Imazethapyr Enantioselectively Affects Chlorophyll Synthesis and Photosynthesis in Arabidopsis thaliana",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "liwei sun",
                "org": ""
            },
            {
                "name": "zhengqi sun",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "xiao han",
                "org": ""
            },
            {
                "name": "qiannan zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2013
    },
    "686OIuhD": {
        "id": "686OIuhD",
        "title": "Isolation, purification and identification of two antioxidant peptides from water hyacinth leaf protein hydrolysates (WHLPH)",
        "abstract": "In order to find novel natural antioxidant peptides, the water hyacinth leaf protein was hydrolyzed by Protamex at optimum condition to prepared water hyacinth leaf protein hydrolysate (WHLPH). And antioxidant properties of WHLPH were evaluated dependent on several in vitro antioxidant systems, including superoxide anion radical-scavenging activity, ABTS cation radical-scavenging activity, reducing power, and metal chelating capacity. WHLPH showed 86.37% of superoxide anion radical-scavenging activity at 1.0 mg/mL, and 56.51% of ABTS cation radical-scavenging activity at 100 μg/mL. At 1.0 mg/mL, the reducing power of WHLPH was 0.92, and the metal chelating capacity was 68.54%. Subsequently, the WHLPH was subjected to consecutive isolation and purification by macroporous resin, gel filtration chromatography, and reverse-phase high-performance liquid chromatography, and two peptide fractions with higher radical-scavenging activity were acquired. Finally, the two peptide fractions were identified to be Phe-Phe-Glu and Leu-Phe, respectively, by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Considering the two peptides’ amino acid composition, their antioxidant properties may be due to the hydrophobic and/or aromatic acid residues in their sequences. The results indicated that the isolated antioxidant peptides from WHLPH would find widespread application in food, cosmetics, and pharmaceutical industry because of their high potency, safety, low cost and abundant source.",
        "keywords": [
            "Water hyacinth leaf protein",
            "Hydrolysate",
            "Radical-scavenging activity",
            "Antioxidant properties",
            "Antioxidant peptides"
        ],
        "authors": [
            {
                "name": "Youwei Zhang",
                "org": "School of Food Science and Technology,Jiangsu Food and Pharmaceutical Science College,Huai’an,China"
            },
            {
                "name": "Yingbin Shen",
                "org": "Department of Food Science and Engineering,Jinan University,Guangzhou,China"
            },
            {
                "name": "Huijun Zhang",
                "org": "School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Li Wang",
                "org": "School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Xiguang Qi",
                "org": "School of Food Science and Technology,Jiangnan University,Wuxi,China"
            }
        ],
        "venue": "European Food Research and Technology",
        "year": 2018
    },
    "Slt5YzjJ": {
        "id": "Slt5YzjJ",
        "title": "Generating signatures with optimal overhead: practical paddings for signature schemes: Optimal signature paddings",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhijie chen",
                "org": ""
            },
            {
                "name": "zhibin li",
                "org": ""
            },
            {
                "name": "yuan zhou",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2014
    },
    "VPyYirij": {
        "id": "VPyYirij",
        "title": "Security authentication protocol based on bilinear pairing",
        "abstract": "A scalable authentication protocol based on bilinear paring was proposed.There are several advantages of the new protocol:(1) By using the bilinear group,the length of public parameter and keys decreases with the same security level,hence we reduce bandwidth needed in communication,thus the protocol is more suitable for the huge internet system.(2) It incorporates a 3-factor authentication mechanism for detecting compromise.(3) The password can be canceled by user's requirement.(4) The protocol has great efficiency and scalable implement.",
        "keywords": [
            "authentication protocol",
            "elliptic curve",
            "bilinear pairing",
            "security",
            "password"
        ],
        "authors": [
            {
                "name": "HUANG Su-shan",
                "org": "Department of Computer Science and Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science and Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "ZHOU Yuan",
                "org": "National Computer Network and In formation Security Administration Center,Beijing ,China"
            }
        ],
        "venue": "Journal of East China Normal University(Natural Science)",
        "year": 2010
    },
    "yKIJNigo": {
        "id": "yKIJNigo",
        "title": "A phone-assistive device based on Bluetooth technology for cochlear implant users.",
        "abstract": "Hearing-impaired people, and particularly hearing-aid and cochlear-implant users, often have difficulty communicating over the telephone. The intelligibility of telephone speech is considerably lower than the intelligibility of face-to-face speech. This is partly because of lack of visual cues, limited telephone bandwidth, and background noise. In addition, cellphones may cause interference with the hearing aid or cochlear implant. To address these problems that hearing-impaired people experience with telephones, this paper proposes a wireless phone adapter that can be used to route the audio signal directly to the hearing aid or cochlear implant processor. This adapter is based on Bluetooth technology. The favorable features of this new wireless technology make the adapter superior to traditional assistive listening devices. A hardware prototype was built and software programs were written to implement the headset profile in the Bluetooth specification. Three cochlear implant users were tested with the proposed phone-adapter and reported good speech quality.",
        "keywords": [
            "audio signal",
            "cellphones",
            "mobile handsets",
            "face-to-face speech intelligibility",
            "limited telephone bandwidth",
            "phone-assistive device",
            "bluetooth technology",
            "assistive listening devices",
            "speech intelligibility",
            "cochlear implant users",
            "prosthetics",
            "hearing-aid users",
            "wireless phone adapter",
            "bluetooth",
            "hearing aids",
            "background noise",
            "telephone speech intelligibility",
            "audio signal processing",
            "hearing-impaired people",
            "handicapped aids",
            "visual cues"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "University of Minnesota, Minneapolis, MN"
            },
            {
                "name": "Philipos C Loizou",
                "org": ""
            },
            {
                "name": "Michael F Dorman",
                "org": ""
            }
        ],
        "venue": "IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society",
        "year": 2003
    },
    "XfIhR19z": {
        "id": "XfIhR19z",
        "title": "You Can Yak but You Can't Hide: Localizing Anonymous Social Network Users.",
        "abstract": "The recent growth of anonymous social network services -- such as 4chan, Whisper, and Yik Yak -- has brought online anonymity into the spotlight. For these services to function properly, the integrity of user anonymity must be preserved. If an attacker can determine the physical location from where an anonymous message was sent, then the attacker can potentially use side information (for example, knowledge of who lives at the location) to de-anonymize the sender of the message. In this paper, we investigate whether the popular anonymous social media application Yik Yak is susceptible to localization attacks, thereby putting user anonymity at risk. The problem is challenging because Yik Yak application does not provide information about distances between user and message origins or any other message location information. We provide a comprehensive data collection and supervised machine learning methodology that does not require any reverse engineering of the Yik Yak protocol, is fully automated, and can be remotely run from anywhere. We show that we can accurately predict the locations of messages up to a small average error of 106 meters. We also devise an experiment where each message emanates from one of nine dorm colleges on the University of California Santa Cruz campus. We are able to determine the correct dorm college that generated each message 100\\\\% of the time.",
        "keywords": "",
        "authors": [
            {
                "name": "Minhui Xue",
                "org": ""
            },
            {
                "name": "Cameron L. Ballard",
                "org": ""
            },
            {
                "name": "Kelvin Liu",
                "org": ""
            },
            {
                "name": "Carson L. Nemelka",
                "org": ""
            },
            {
                "name": "Yanqiu Wu",
                "org": ""
            },
            {
                "name": "Keith W. Ross",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Internet Measurement Conference",
        "year": 2016
    },
    "yok4o9bQ": {
        "id": "yok4o9bQ",
        "title": "Nitric oxide enhanced reduction in a rotating drum biofilter coupled with absorption by FeII(EDTA)",
        "abstract": "BACKGROUND: The ongoing emission of nitric oxide (NO) is a serious persistent environmental problem, because it contributes to atmospheric ozone destruction and global warming. A novel and effective system was developed for the complete treatment of NO from flue gases. The system features NO absorption by FeII(EDTA) and biological denitrification in a rotating drum biofilter (RDB). RESULTS: After 100 mg L-1 FeII(EDTA) was added to the nutrient solution, the results show that the NO removal efficiency was improved from 70.56% to 80.15%, the optimal temperature improved from 32.5 °C to 40.5 °C, and the pH improved from 7.5 to 8.0-8.3. A maximum NO removal efficiency of 96.5% was achieved when 500 mg L-1 FeII(EDTA) was used in the nutrient solution. CONCLUSION: This experiment demonstrates that FeII(EDTA) could not only improve the mass transfer efficiency of NO from gas to liquid, but also serve as an electron donor for the biological reduction of NO to N2. The new integrated treatment system seemed to be a promising alternative for the complete treatment of NO from flue gases. © 2012 Society of Chemical Industry.",
        "keywords": [
            "air pollution control",
            "denitrification",
            "feii(edta)",
            "nitric oxide",
            "rdb",
            "removal efficiency"
        ],
        "authors": [
            {
                "name": "Jun Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Qizhou Dai",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Yifeng Jiang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Jianmeng Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Journal of Chemical Technology and Biotechnology",
        "year": 2013
    },
    "YE7fQbnj": {
        "id": "YE7fQbnj",
        "title": "Investigation the molecular degradation, starch-lipid complexes formation and pasting properties of wheat starch in instant noodles during deep-frying treatment.",
        "abstract": "The effects of frying temperature and time on the amylose content, thermodynamic properties, crystalline properties, and pasting properties of starch in wheat-flour based noodles were investigated. The amylose content increased when the frying temperature increased or the frying time extended. Differential scanning calorimetry confirmed the formation of starch-lipid complexes. ΔH of the complexes increased sharply from 0.91 to 1.40 J/g with increased frying temperature, while it initially increased from 1.01 to 1.40 J/g and then decreased rapidly to 1.17 J/g with prolonged frying time. These observations were consistent with the results of relative crystallinity. Rapid viscosity analysis showed that the viscosities decreased by the increasing frying temperature or the prolonging frying time. The results showed that the deep-frying process destroyed the starch structure and led to the formation of starch-lipid complexes.",
        "keywords": [
            "DSC",
            "Deep-frying",
            "RVA",
            "The amylose content",
            "XRD"
        ],
        "authors": [
            {
                "name": "Yi Yang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hai Feng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Gang Cheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xi Guang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "4HmtC0Kw": {
        "id": "4HmtC0Kw",
        "title": "The effect of oat β -glucan on in vitro glucose diffusion and glucose transport in rat small intestine: Effect of β-glucan on glucose in rats",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "bo hu",
                "org": ""
            },
            {
                "name": "jiajia li",
                "org": ""
            },
            {
                "name": "xiangli ding",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "yu zhang",
                "org": ""
            }
        ],
        "venue": "Journal of the Science of Food and Agriculture",
        "year": 2015
    },
    "A3RhBKBw": {
        "id": "A3RhBKBw",
        "title": "Unraveling the Toxicity Mechanisms of the Herbicide Diclofop-Methyl in Rice: Modulation of the Activity of Key Enzymes Involved in Citrate Metabolism and Induction of Cell Membrane Anion Channels",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "xiaolu lv",
                "org": ""
            },
            {
                "name": "yali li",
                "org": ""
            },
            {
                "name": "jun xie",
                "org": ""
            },
            {
                "name": "michel lavoie",
                "org": ""
            },
            {
                "name": "haiping lu",
                "org": ""
            },
            {
                "name": "haiyan ding",
                "org": ""
            }
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2014
    },
    "e8VPDPpn": {
        "id": "e8VPDPpn",
        "title": "Comparison of functional properties and secondary structures of defatted wheat germ proteins separated by reverse micelles and alkaline extraction and isoelectric precipitation",
        "abstract": "The functional properties and secondary structures of defatted wheat germ protein separated by reverse micelles (DWGRMPI) were investigated and compared with those of defatted wheat germ protein separated by alkaline extraction and isoelectric precipitation (DWGPI). The results showed that DWGRMPI had a higher nitrogen solubility index, fat absorption capacity, foaming capacity, foaming stability and emulsifying stability compared to DWGPI, whilst water holding capacity, surface hydrophobicity and emulsifying activity of DWGRMPI were relatively lower than those of DWGPI. DWGRMPI contained high levels of threonine, histidine, alanine, arginine, glycine, serine, cysteine, proline and especially lysine compared to DWGPI. The denaturation temperature and denaturation enthalpy of DWGPI were both lower than those of DWGRMPI, and DWGPI contained more random coil and less α-helix than DWGRMPI, which suggested that DWGPI has lost its ordered secondary structure. This may possibly due to the conditions the used in protein extraction.",
        "keywords": [
            "defatted wheat germ protein",
            "functional properties",
            "secondary structure",
            "alkaline extraction and isoelectric precipitation",
            "reverse micelles",
            "precipitation",
            "foaming",
            "denaturation",
            "stability",
            "chemical composition",
            "extraction",
            "chemical structure",
            "temperature",
            "hydrophobicity",
            "micelles",
            "indexation",
            "nitrogen"
        ],
        "authors": [
            {
                "name": "Ke-Xue Zhu",
                "org": ""
            },
            {
                "name": "Xiao-Hong Sun",
                "org": "College of Life Science and Engineering, Qiqihar University, Qiqihar 161006, Heilongjiang Province, PR China"
            },
            {
                "name": "Zhi-Cheng Chen",
                "org": "School of Cereal, Oil and Food Science, Henan University of Technology, 140 Songshan South Road, Zhengzhou 450052, Henan Province, PR China"
            },
            {
                "name": "Wei Peng",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China"
            },
            {
                "name": "Hai-Feng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China"
            },
            {
                "name": "Hui-Ming Zhou",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China"
            }
        ],
        "venue": "Food Chemistry",
        "year": 2010
    },
    "tXZjocCy": {
        "id": "tXZjocCy",
        "title": "Verification of the GSICS GEO-LEO inter-calibration products with GEO-GEO collocation data",
        "abstract": "",
        "keywords": [
            "climate change",
            "radiative transfer model",
            "orbital dynamics",
            "methane",
            "data quality",
            "optical path difference",
            "infrared",
            "calibration",
            "satellites"
        ],
        "authors": [
            {
                "name": "fangfang yu",
                "org": "eresearch technology inc"
            },
            {
                "name": "xiangqian wu",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "gordana sindicrancic",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "wXmKcbO1": {
        "id": "wXmKcbO1",
        "title": "Photoperiod and temperature influence cadmium's effects on photosynthesis-related gene transcription in Chlorella vulgaris.",
        "abstract": "Routine metal compound toxicity tests are performed at one constant photoperiod and temperature. There is little knowledge about the interactions between metal compound toxicity and photoperiod or temperature. The purpose of this study was to analyze the effects of photoperiod and temperature on cadmium (Cd) toxicity in the fresh alga, Chlorella vulgaris, both singly and in combination. Exposure to 2 or 4 microM Cd alone significantly decreased the transcription of the photosynthesis-related genes psbA, psaB and rbcL. Three-way ANOVA analysis showed that both temperature and photoperiod interacted with the dosage of Cd to influence the abundance of psbA and psaB, but not rbcL. Specifically, psbA transcription was more sensitive to Cd under long photoperiods or high temperatures than under short photoperiods or low temperatures. Because photoperiod and temperature have certain impacts on the toxicity of metal compounds, these two environmental factors should be given more attention in laboratory research.",
        "keywords": [
            "cadmium",
            "gene transcription",
            "photoperiod",
            "temperature",
            "toxicity testing"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Jingjing Li",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Haiyan Jiang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2010
    },
    "XfIPP9AU": {
        "id": "XfIPP9AU",
        "title": "The Certainty of Uncertainty: Randomness in Nanometer Design",
        "abstract": "\n Randomness and uncertainty are rearing their heads in surprising and contradictory ways in nanometer technologies. On the\n one hand, uncertainty and variability is becoming a dominant factor in the design of integrated circuits, and on the other\n hand, algorithms based on randomness are beginning to show great promise in solving large scale problems. This paper overviews\n both aspects of this issue.\n \n ",
        "keywords": [
            "integrated circuit"
        ],
        "authors": [
            {
                "name": "Hongliang Chang",
                "org": "CSE Department"
            },
            {
                "name": "Haifeng Qian",
                "org": "ECE Department, University of Minnesota, Minneapolis, MN 55455, USA"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "ECE Department, University of Minnesota, Minneapolis, MN 55455, USA"
            }
        ],
        "venue": "PATMOS",
        "year": 2004
    },
    "CZeo1n2o": {
        "id": "CZeo1n2o",
        "title": "Effect of salicylic acid on fatty acid accumulation in Phaeodactylum tricornutum during stationary growth phase",
        "abstract": "Microalgae possess great potential for use as raw materials for biofuel production. The marine diatom Phaeodactylum tricornutum accumulates lipids as its major form of energy storage when grown under specific conditions. This study investigated the effects of salicylic acid (SA) on the accumulation of fatty acids in P. tricornutum in the stationary growth phase. Our results showed that 40 μM SA increased the total fatty acid content accumulation 1.3-fold of the control after 4 days of exposure. The metabolomics data indicated that SA stimulated the fatty acid monostearin, 2-monoolein, monoolein, and methyl palmitoleate to 22.7-, 16.3-, 3.47-, and 3.47-fold of the control, respectively. The results of physiological and gene transcriptional levels revealed that the glycolysis, N assimilation, and fatty acid synthesis pathways were induced by SA treatment and thus accelerated fatty acid synthesis from carbohydrate and N compounds. The SA treatment could be used to optimize biodiesel production.",
        "keywords": "",
        "authors": [
            {
                "name": "Jiahui Xu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Xiaoji Fan",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Xingxing Li",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Guanfu Liu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Youchao Zhu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology"
            }
        ],
        "venue": "Journal of Applied Phycology",
        "year": 2017
    },
    "sUHalkYj": {
        "id": "sUHalkYj",
        "title": "Two-source extractors for leaky sources.",
        "abstract": "",
        "keywords": [
            "cryptography"
        ],
        "authors": [
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "ITW",
        "year": 2012
    },
    "hcmUi4Sh": {
        "id": "hcmUi4Sh",
        "title": "Extraction of Carrot (Daucus carota) Antifreeze Proteins and Evaluation of Their Effects on Frozen White Salted Noodles",
        "abstract": "Homogenate and vacuum infiltration-centrifugation were adopted and compared in carrot antifreeze proteins (CaAFPs) extraction, and effects of CaAFPs on thermophysical properties, texture properties, cooking properties, and microstructure of frozen white salted noodles were studied. Results showed that the vacuum infiltration-centrifugation was more targeted than homogenate in CaAFPs extraction, while its protein extraction rate was much lower than homogenate. Differential scanning calorimeter measurement showed that CaAFPs could not only lower the initial point of freezing (T f) and the end point of freezing (T m��) of water but also decrease the freezable water content. It also confirmed that CaAFPs were enriched in apoplast extract. The addition of CaAFPs could lower the enthalpy of melting of frozen noodles. V-CaAFPs could lower T m�� of frozen noodles but the T m�� of H-noodles was slightly increased. Freezable water content of frozen noodles was decreased by the addition of CaAFPs and T g�� of them was increased. Texture profile analysis showed that texture properties of white salted noodles were significantly influenced (p < 0.05) by the addition of CaAFPs. Cooking properties of frozen white salted noodles were also significantly enhanced (p < 0.05) by increasing cooking absorption and reducing dry material loss. NMR measurement showed that the addition of CaAFPs could shift water from mobile state to less mobile state. Microstructure of noodles suggested that the addition of CaAFPs could protect the gluten network from the damage caused by freezing and temperature fluctuation, which resulted in an integrated gluten network in white salted noodles. ? 2013 Springer Science+Business Media New York.",
        "keywords": [
            "antifreeze proteins",
            "carrot (daucus carota)",
            "homogenate",
            "noodles properties",
            "vacuum infiltration-centrifugation"
        ],
        "authors": [
            {
                "name": "Xiangli Ding",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Wenhua Liu",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Li Wang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Xiguang Qi",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "Food and Bioprocess Technology",
        "year": 2014
    },
    "REUQ17H8": {
        "id": "REUQ17H8",
        "title": "Effects of different concentrations of Microcystis aeruginosa on the intestinal microbiota and immunity of zebrafish (Danio rerio).",
        "abstract": "Microcystis aeruginosa is a primary species of toxin-producing cyanobacteria. This study explored the effects of short-term exposure (96 h) to M. aeruginosa on the intestinal microflora variation and immune function of zebrafish. After exposure to different cell concentrations of M. aeruginosa, marked histological variation was observed in the intestine, such as goblet cells proliferation and intestinal desquamation. In addition high-concentration M. aeruginosa treatment (initial concentration: 1.59 × 10 cells mL) induced a significant increase in cytokine levels compared with other groups. Low-concentration M. aeruginosa treatment (initial concentration: 0.88 × 10 cells mL) promoted the transcription of inflammatory genes, while high-concentration treatment restrained the transcription of these genes. Moreover, M. aeruginosa exposure also changed the intestinal microbial diversity. At the phylum level, bacteria belonging to Proteobacteria were the most abundant in all groups, and Gammaproteobacteria were the dominant bacteria with major changes. Pathogenic microorganisms such as Shewanella, Plesiomonas, Halomonas, Pseudomonas, and Lactobacillus increased greatly after treatment with different cell concentrations of M. aeruginosa. This study indicates that M. aeruginosa induces an increase in zebrafish goblet cells and enhances the inflammatory response, which may produce detrimental effects in zebrafish, resulting in a greater proportion of pathogenic bacteria and intestinal injury. The results of this study will help improve the understanding of the effects of M. aeruginosa on the intestines of aquatic organisms.",
        "keywords": [
            "Cytokines",
            "Intestine inflammation",
            "Microbiota",
            "Microcystis aeruginosa",
            "Zebrafish"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, 830011, PR China; College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Guangfu Liu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: panxl@zjut.edu.cn."
            }
        ],
        "venue": "Chemosphere",
        "year": 2018
    },
    "ZCi4OYdN": {
        "id": "ZCi4OYdN",
        "title": "Effect of ultrafine grinding on hydration and antioxidant properties of wheat bran dietary fiber",
        "abstract": "Wheat bran dietary fiber (DF) powders was prepared by ultrafine grinding, whose effects were investigated on the composition, hydration and antioxidant properties of the wheat bran DF products. The results showed that ultrafine grinding could effectively pulverize the fiber particles to submicron scale. As particle size decrease, the hydration properties (water holding capacity, water retention capacity and swelling capacity) of wheat bran DF were significantly ( p < 0.05) decreased and a redistribution of fiber components from insoluble to soluble fractions was observed. The antioxidant activities of wheat bran and DF before and after grinding were in terms of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, ferrous ion-chelating activity, reducing power and total phenolic content (TPC). Compared with DF before and after grinding, micronized insoluble DF showed increased chelating activity, reducing power and TPC yet decreased DPPH˙ radical scavenging activity. Positive correlations were detected between chelating activity, reducing power and TPC. Keywords Ultrafine grinding Submicron Hydration properties Antioxidant properties Dietary fiber",
        "keywords": [
            "antioxidant properties",
            "dietary fiber",
            "hydration properties",
            "submicron",
            "ultrafine grinding",
            "particle size"
        ],
        "authors": [
            {
                "name": "KeXue Zhu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue Wuxi-214122, Jiangsu Province, PR China"
            },
            {
                "name": "Sheng Huang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue Wuxi-214122, Jiangsu Province, PR China"
            },
            {
                "name": "Wei Peng",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue Wuxi-214122, Jiangsu Province, PR China"
            },
            {
                "name": "HaiFeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue Wuxi-214122, Jiangsu Province, PR China"
            },
            {
                "name": "HuiMing Zhou",
                "org": ""
            }
        ],
        "venue": "Food Research International",
        "year": 2010
    },
    "bdydl5c2": {
        "id": "bdydl5c2",
        "title": "A method for evaluating Hunter whiteness of mixed powders",
        "abstract": "The Hunter whiteness (HW) is an important quality index of powder in agricultural, food and pigment industries. Relationship between HW of mixed powder and mass percent of each individual powder was investigated. We found a linear relationship expressed by a corresponding equation. According to this equation, the HW of mixed powder was only related to the HW and mass percent of each kind of individual power. Therefore, such equation can simply and rapidly evaluate HW of the mixed powder during the powder matching process. (C) 2008 The Society of Powder Technology Japan. Published by Elsevier BV and The Society of Powder Technology Japan. All rights reserved.",
        "keywords": [
            "Mixed powder",
            "Linear relationship",
            "Hunter whiteness",
            "Mass percent"
        ],
        "authors": [
            {
                "name": "Kerui Zhu",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            },
            {
                "name": "Philip John Kanu",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            },
            {
                "name": "Irakoze Pierre Claver",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            },
            {
                "name": "Kexue Zhu",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            },
            {
                "name": "Huiming Zhou",
                "org": "Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu Prov, Peoples R China"
            }
        ],
        "venue": "ADVANCED POWDER TECHNOLOGY",
        "year": 2009
    },
    "6vf5OefK": {
        "id": "6vf5OefK",
        "title": "Toward optimizing cauchy matrix for cauchy reed-solomon code",
        "abstract": "The computational costs of Cauchy Reed-Solomon (CRS) encoding operation make a great impact on the performance of its practical applications. The letter concentrates on how to construct a good Cauchy matrix which can lead to an efficient CRS coding scheme. We first formally model the problem by using a binary quadratic programming, then present an approximate method called localized greedy algorithm (LGA) to solve it. Compared with existing work, LGA requires much lower complexities to obtain the same performance of Cauchy matrices.",
        "keywords": [
            "efficient crs coding scheme",
            "encoding operation",
            "quadratic programming",
            "computational cost",
            "cauchy matrix",
            "disaster tolerance",
            "reed-solomon codes",
            "matrix algebra",
            "binary quadratic programming",
            "greedy algorithm",
            "cauchy reed-solomon code",
            "localized greedy algorithm",
            "greedy algorithms",
            "good cauchy matrix",
            "cauchy reed-solomon",
            "great impact",
            "optimizing cauchy matrix",
            "reed-solomon code",
            "approximate method",
            "reed-solomon encoding operation",
            "binary quadratic programming.",
            "polynomials",
            "approximation algorithms",
            "quadratic program",
            "mathematical model",
            "algorithm design and analysis",
            "encoding",
            "reed solomon code",
            "data mining",
            "optimization",
            "reed solomon",
            "galois fields",
            "information security"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": "School of Information Security Engineering, Shanghai Key Lab of Inform. Security Management and Tech. Research, and ISN State Key Lab., Shanghai Jiaotong Univ."
            },
            {
                "name": "Qingji Zheng",
                "org": "School of Information Security Engineering, Shanghai Key Lab of Inform. Security Management and Tech. Research, and ISN State Key Lab., Shanghai Jiaotong Univ."
            },
            {
                "name": "Haifeng Qian",
                "org": "CS, ECNU"
            },
            {
                "name": "Dong Zheng",
                "org": "School of Information Security Engineering, Shanghai Key Lab of Inform. Security Management and Tech. Research, and ISN State Key Lab., Shanghai Jiaotong Univ."
            },
            {
                "name": "Jianhua Li",
                "org": "School of Information Security Engineering, Shanghai Key Lab of Inform. Security Management and Tech. Research, and ISN State Key Lab., Shanghai Jiaotong Univ."
            }
        ],
        "venue": "IEEE Communications Letters",
        "year": 2009
    },
    "08OwENbN": {
        "id": "08OwENbN",
        "title": "Allelopathic interactions of linoleic acid and nitric oxide increase the competitive ability of Microcystis aeruginosa.",
        "abstract": "The frequency and intensity of cyanobacterial blooms are increasing worldwide with major societal and economic costs. Interactions between toxic cyanobacteria and eukaryotic algal competitors can affect toxic bloom formation, but the exact mechanisms of interspecies interactions remain unknown. Using metabolomic and proteomic profiling of co-cultures of the toxic cyanobacterium Microcystis aeruginosa with a green alga as well as of microorganisms collected in a Microcystis spp. bloom in Lake Taihu (China), we disentangle novel interspecies allelopathic interactions. We describe an interspecies molecular network in which M. aeruginosa inhibits growth of Chlorella vulgaris, a model green algal competitor, via the release of linoleic acid. In addition, we demonstrate how M. aeruginosa takes advantage of the cell signaling compound nitric oxide produced by C. vulgaris, which stimulates a positive feedback mechanism of linoleic acid release by M. aeruginosa and its toxicity. Our high-throughput system-biology approach highlights the importance of previously unrecognized allelopathic interactions between a broadly distributed toxic cyanobacterial bloom former and one of its algal competitors.",
        "keywords": "",
        "authors": [
            {
                "name": "Hao Song",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Lavel, QC, Canada."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Hana Tan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Guangfu Liu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Pengfei Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China."
            },
            {
                "name": "Hans W Paerl",
                "org": "College of Environment, Hohai University, Nanjing, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, China."
            }
        ],
        "venue": "The ISME journal",
        "year": 2017
    },
    "Gb6VPh3O": {
        "id": "Gb6VPh3O",
        "title": "Multi-resolution codebook design for two-stage precoding in FDD massive MIMO networks.",
        "abstract": "In this paper, we develop a new codebook design method for multi-resolution codebook based two-stage precoding scheme in massive MIMO networks in frequency division duplex (FDD) mode. A narrow-beam generated by each codeword is intended to provide coverage over certain beam range with strict constraints on the average and the variation in the radiated power. Each narrow-beam or codeword is designed based on a new performance metric, the ratio of the expected average power within the coverage beam range to that outside the beam range, i.e., beam-to-leakage ratio (BLR). An optimization problem for narrow-beam design is formulated to maximize the BLR. The codebook is generated via solving the optimization problem. Based on numerical evaluation, our novel codebook design based transmission scheme can improve the overall network throughput compared with the DFT-based and covariance based method when the angular spread of the channel is relative large or when the channel is rich scattering.",
        "keywords": "",
        "authors": [
            {
                "name": "Deli Qiao",
                "org": "East China Normal Univ, Sch Informat Sci & Technol, Shanghai, Peoples R China"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal Univ, Sch Comp Sci & Software Engn, Shanghai, Peoples R China"
            },
            {
                "name": "Geoffrey Ye Li",
                "org": "Georgia Inst Technol, Sch Elect & Comp Engn, Atlanta, GA 30332 USA"
            }
        ],
        "venue": "PROCEEDINGS OF THE 2ND INTERNATIONAL CONFERENCE ON EDUCATIONAL MANAGEMENT AND ADMINISTRATION (COEMA 2017)",
        "year": 2017
    },
    "WgwcOzKj": {
        "id": "WgwcOzKj",
        "title": "Study on water absorption kinetics of black beans during soaking",
        "abstract": "Abstract   Soaking can affect the final quality of black bean products. The Peleg equation and low field nuclear magnetic resonance (LF-NMR) were used to study the water absorption kinetics of black beans during soaking. From the results, the changing of the water content in black beans during soaking at 30–70 °C can be simulated by the Peleg equation. The rate constant      K   1       and the capacity constant      K  2      decreased with an increase of temperature, the relationship between temperature and its corresponding rate constant      K  1      were fitted to the Arrhenius equation, and the activation energy of the soaking process was 32.09    k  J  m  o   l   −  1      , indicating that the seed hydration rate was more sensitive to temperature. Three proton fractions with different mobility were observed in black beans during soaking, reflecting macromolecule, oil, and water in different microenvironments; the soaking process significantly changed the distribution of proton fractions in black beans. Magnetic resonance imaging (MRI) showed that the water first passes through the uneven wall and then enters the inner region of the black beans along the different channels during the soaking process, leading to significant changes in the texture of black beans.",
        "keywords": "",
        "authors": [
            {
                "name": "Peng Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China"
            }
        ],
        "venue": "Journal of Food Engineering",
        "year": 2020
    },
    "uQCuaU9g": {
        "id": "uQCuaU9g",
        "title": "The combined toxicity effect of nanoplastics and glyphosate on Microcystis aeruginosa growth.",
        "abstract": "Waste plastics can be degraded to nanoplastics (NPs, diameter<1 μm) by natural forces. NPs not only directly affect aquatic organisms but also adsorb other pollutants, causing combined pollution. Glyphosate is one of the most widely used herbicides and is commonly monitored in freshwater systems. In this study, the effects of the combined toxicity of polystyrene cationic amino-modified nanoparticles (nPS-NH) and glyphosate on a blue-green alga, Microcystis aeruginosa, were investigated. Our results demonstrated that 5 mg/L glyphosate had a strong inhibitory effect on M. aeruginosa (the 96-h inhibitory rate was 27%), while 5 mg/L nPS-NH had no apparent effect on the growth of M. aeruginosa. Interestingly, nPS-NH combined with glyphosate showed antagonistic effects on the inhibition of algal growth because nPS-NH displayed a strong adsorption capacity for glyphosate, which significantly alleviated the inhibitory effect of glyphosate on M. aeruginosa growth. However, the presence of glyphosate enhanced the stability of the dispersion system, which allowed more nPS-NH to adsorb on the surface of M. aeruginosa and may result in greater enrichment of nPS-NH in the food chain to show potential repercussions to human life. Our current study provides a new theoretical basis for the combined effects of NPs and pesticide pollution.",
        "keywords": [
            "Adsorption",
            "Combined toxicity",
            "Glyphosate",
            "Herbicide",
            "Nanoplastic"
        ],
        "authors": [
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2018
    },
    "uTA9tBPD": {
        "id": "uTA9tBPD",
        "title": "A novel ID-Based partial delegation with warrant proxy signature scheme",
        "abstract": "A novel ID-based proxy-protected signature scheme based on identity information is presented in this paper. We review the concept ID-Based signature introduced by Shamir, define the security notion of an ID-Based signature. We also improve the Shamir’s ID-Based signature and prove its security under the proposed security notion. From the improved Shamir’s ID-Based signature scheme we construct an ID-Based proxy signature scheme, the security is based on the underlying ID-based signature scheme. Our scheme is efficient and easy to implement. The scheme simplifies the public key as the user’s id and can be easily applied to all the RSA-type cryptosystems.",
        "keywords": [
            "rsa-type cryptosystems",
            "improved shamir",
            "warrant proxy signature scheme",
            "security notion",
            "underlying id-based signature scheme",
            "id-based signature",
            "id-based proxy signature scheme",
            "concept id-based signature",
            "proxy-protected signature scheme",
            "partial delegation",
            "proposed security notion",
            "id-based signature scheme",
            "it security",
            "random oracle model",
            "public key",
            "provable security"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science, Shanghai Jiao Tong University, Shanghai, China"
            }
        ],
        "venue": "ISPA Workshops",
        "year": 2005
    },
    "CNpktbdn": {
        "id": "CNpktbdn",
        "title": "Row Based Dual-VDD Island Generation and Placement",
        "abstract": "Power consumption has become a major consideration in nanometer chip design. Since the dynamic power is proportional to V dd2, and the static power is proportional to V dd, lowering power supply voltage is an efficient method to reduce the power usage. In this paper, we adopt the row-based dual-supply voltage (DSV) scheme. DSV assigns a low power supply voltage to timing non-critical gates for the power saving. Contrary to the traditional region-based voltage island works, the row-based approach creates voltage islands along the circuit rows. This kind of fine grid voltage islands give more flexibility on gate voltage assignment such that the low voltage gates can be selected primarily based on timing and design logic, which in turn minimizes the shifter insertion. We present a two-stage flow to generate voltage islands for every two mirrored circuit rows and place gates legally inside each island. To the best of our knowledge, this is also the first work to cover latch and LCB (local clock buffer) handling and shifter placement in voltage island generation. The experimental results demonstrate the effectiveness and efficiency of our approach.",
        "keywords": [
            "circuit rows",
            "algorithms",
            "design",
            "nanometer chip design",
            "power consumption",
            "shifter insertion",
            "microprocessor chips",
            "power saving",
            "low-power electronics",
            "shifter placement",
            "local clock buffer",
            "placement",
            "gate voltage assignment",
            "clocks",
            "lcb",
            "design aids",
            "integrated circuit design",
            "buffer circuits",
            "row based dual-supply voltage island generation",
            "dual supply voltage",
            "fine grid voltage islands",
            "nanoelectronics",
            "clustering"
        ],
        "authors": [
            {
                "name": "Hua Xiang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Ching Zhou",
                "org": ""
            },
            {
                "name": "Yu-Shiang Lin",
                "org": ""
            },
            {
                "name": "Fanchieh Yee",
                "org": ""
            },
            {
                "name": "Andrew Sullivan",
                "org": ""
            },
            {
                "name": "Pong-Fei Lu",
                "org": ""
            }
        ],
        "venue": "DAC",
        "year": 2014
    },
    "pQXzNHUY": {
        "id": "pQXzNHUY",
        "title": "Imazethapyr enantioselectively affects chlorophyll synthesis and photosynthesis in Arabidopsis thaliana.",
        "abstract": "Imazethapyr (IM) is a chiral herbicide with reported enantioselective biological activities between its enantiomers. This report investigated the effect of enantioselectivity between R- and S-IM in Arabidopsis thaliana on chlorophyll synthesis and photosynthesis. The results suggest that R-IM inhibited the transcription of chlM to a greater extent than S-IM, which reduced chlorophyll synthesis. R-IM also showed a stronger inhibitory effect than S-IM on the transcription of photosynthesis-related genes, affecting linear electron transport and CO(2) fixation. IM stress enantioselectively induced transcriptional upregulation of the ndhH gene, a representative of the NDH complex. In contrast, the expression of pgr5 was downregulated, which demonstrated that IM stress enhanced adenosine 5'-triphosphate (ATP) synthesis by stimulating an NDH-dependent and not ferredoxin (FD)-independent route. This study suggested that R-IM has a greater toxic effect on photosynthesis than S-IM, affecting plant growth through chlorophyll synthesis.",
        "keywords": [
            "imazethapyr",
            "photosynthesis",
            "chlorophyll synthesis",
            "cyclic electron transport",
            "enantioselectivity"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xiao Han",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Qiannan Zhang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengqi Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Liwei Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2013
    },
    "VGoJoTYE": {
        "id": "VGoJoTYE",
        "title": "Phosphorus availability changes chromium toxicity in the freshwater alga Chlorella vulgaris.",
        "abstract": "Chromium (Cr) is one of the most serious pollutants in aquatic systems. This study examined the relationship between the toxic effects of Cr on the freshwater alga Chlorella vulgaris and phosphorus (P) availability on the algal physiology and ultrastructure. Cr inhibited C. vulgaris growth in a concentration- and time-dependent manner, and its inhibitory effect was related to the P concentration. In a low-P medium, Cr showed approximately 2.2-3.7-fold stronger toxicity than in a high-P medium. Cr was absorbed into the algal body where it disrupted the chloroplast structure and decreased the chlorophyll content. However, Cr had a weaker chlorophyll inhibitory ability and destructive power against the chloroplasts in the high-P medium than in the low-P medium due to the partial blockage of Cr absorption in high P-medium. Cr exposure also changed the metal ion and anion absorption profiles, which was also closely related to the concentration of P. Cr treatment increased the volume of the vacuole, and the larger vacuole reduced the space available for chloroplasts, as based on optical and electron microscopy results, but a higher P availability could alleviate this damage. These results suggest that high P alleviated the toxicity of Cr by decreasing Cr absorption and increasing the absorption of beneficial ions. It is, therefore, necessary to consider the phosphorus availability when the toxicity of metal compounds is evaluated.",
        "keywords": [
            "substructure",
            "phosphorus",
            "Chromium",
            "chlorella vulgaris",
            "ion absorption",
            "Ion absorption",
            "Phosphorus",
            "Substructure",
            "chromium",
            "Chlorella vulgaris"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengqi Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Liwei Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Yifeng Jiang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Yong Wei",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Jun Xie",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Chemosphere",
        "year": 2013
    },
    "Jw7FIayB": {
        "id": "Jw7FIayB",
        "title": "Detection and characterization of striping in GOES-16 ABI VNIR/IR bands.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Robert Iacovazzi",
                "org": ""
            },
            {
                "name": "Zhipeng Wang",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2018
    },
    "0eWUAuDi": {
        "id": "0eWUAuDi",
        "title": "Antimicrobial peptide isolated from ovalbumin hydrolysate by immobilized liposome-binding extraction",
        "abstract": "Antimicrobial peptides are of greatest potential as a new group of antibiotics. Enzymatic hydrolysis was performed using flavourzyme, pepsin, trypsin, neutrase, papain and alcalase to obtain antimicrobial peptides from ovalbumin. Pepsin hydrolysate exhibited the highest antimicrobial activity compared with other fractions. To purify and characterize antimicrobial peptide, an immobilized liposome-binding extraction method was developed, in which the liposome was regarded as a mimic biomembrane system. The immobilized liposome stationary phase was prepared, and the maximum adsorption capacity and Langmuir constant were 81.30 μM/g and 8.19 mL/mg, respectively. Four fragments were simultaneously predicted by the comparison between reverse-phase high-performance liquid chromatography chromatograms of pepsin hydrolysate before and after interaction with immobilized liposome membrane. A novel cationic antimicrobial peptide named Opep2 was sequenced as RVASMASEKMKI. In addition, antimicrobial mode experiments showed that Opep2 interacted with cell wall membrane and caused potassium efflux, nucleotide leakage and ultimately cell death. Because of the high efficiency and procedural simplicity, the immobilized liposome-binding extraction method could be more efficient for the screening of antimicrobial peptides than conventional methods, which provides scientific references for antimicrobial peptide production. © 2013 Springer-Verlag Berlin Heidelberg.",
        "keywords": [
            "Antimicrobial peptide",
            "Ovalbumin",
            "Immobilized liposome-binding extraction",
            "Hydrolysate"
        ],
        "authors": [
            {
                "name": "Wenting Tang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Li Wang",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan University(Jiangnan University),Wuxi,China"
            }
        ],
        "venue": "European Food Research and Technology",
        "year": 2013
    },
    "rpJsSE62": {
        "id": "rpJsSE62",
        "title": "Anonymous password-based key exchange with low resources consumption and better user-friendliness: A-PAKE with low resources consumption and better user-friendliness",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "junqing gong",
                "org": ""
            },
            {
                "name": "yuan zhou",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2012
    },
    "3y4GVP2f": {
        "id": "3y4GVP2f",
        "title": "Preparation of wheat gluten hydrolysates with high opioid activity",
        "abstract": "The opioid activity of wheat gluten hydrolysates (WGHs) prepared with several proteases was investigated in vitro by the contraction\n of guinea pig ileum (GPI), and WGHs with high opioid activity were further obtained through desalting and ultrafiltration\n (UF). The opioid activity varied with different wheat gluten hydrolysates. AWGH (WGH prepared with Alcalase), PPWGH (WGH prepared\n with Pepsin followed by Pancreatin) and PWGH (WGH prepared with pepsin) had relatively stronger inhibitory effects on the\n contraction of GPI with IC50 values of 1.21 ± 0.25, 1.29 ± 0.38 and 1.57 ± 0.21 mg protein/ml, respectively. Subsequently, AWGH and PPWGH were desalted\n using cation exchange resin and anion exchange resin, with high nitrogen recovery (88.51 and 89.28%, respectively) and high\n desalting ratio (84.67 and 85.20%). The resultant hydrolysates were further fractionated by UF performed with a 3 kDa molecular\n weight cut-off membrane. Compared with AWGH and PPWGH, the 3 kDa-permeates have higher opioid activities with high protein\n content above 90% and low ash content about 1.5%. The molecular weight distributions of the two 3 kDa-permeates were concentrated\n below 2,000 Da.",
        "keywords": [
            "wheat glutenhydrolysates � opioid activitydesaltingultrafiltration"
        ],
        "authors": [
            {
                "name": "XiangZhen Kong",
                "org": "Jiangnan University State Key Laboratory of Food Science and Technology, School of Food Science and Technology 1800 Lihu Avenue Wuxi 214122 Jiangsu Province People’s Republic of China"
            },
            {
                "name": "HuiMing Zhou",
                "org": "Jiangnan University State Key Laboratory of Food Science and Technology, School of Food Science and Technology 1800 Lihu Avenue Wuxi 214122 Jiangsu Province People’s Republic of China"
            },
            {
                "name": "YuFei Hua",
                "org": "Jiangnan University State Key Laboratory of Food Science and Technology, School of Food Science and Technology 1800 Lihu Avenue Wuxi 214122 Jiangsu Province People’s Republic of China"
            },
            {
                "name": "HaiFeng Qian",
                "org": "Jiangnan University State Key Laboratory of Food Science and Technology, School of Food Science and Technology 1800 Lihu Avenue Wuxi 214122 Jiangsu Province People’s Republic of China"
            }
        ],
        "venue": "European Food Research and Technology",
        "year": 2008
    },
    "g4ufHeIx": {
        "id": "g4ufHeIx",
        "title": "Biased Bit Commitment and Applications",
        "abstract": "We bring forward the primitive of biased bit commitment, define the security of the model, and present a concrete biased bit commitment scheme based on the braid conjugator search problem. The presented scheme is proved to be information-theoretically hiding and computationally binding in the defined model. Finally, to argue the usefulness of this work, we also sketch out some new applications based on this new primitive.",
        "keywords": [
            "biased bit commitment",
            "braid group",
            "conjugactor search problem",
            "coin tossing",
            "lot-casting"
        ],
        "authors": [
            {
                "name": "Licheng Wang",
                "org": "Shanghai Jiao Tong Univ, Dept Comp Sci & Engn, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong Univ, Dept Comp Sci & Engn, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Feng Cao",
                "org": "Shanghai Jiao Tong Univ, Dept Comp Sci & Engn, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiao Tong Univ, Dept Comp Sci & Engn, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Haiyong Bao",
                "org": "Shanghai Jiao Tong Univ, Dept Comp Sci & Engn, Shanghai 200030, Peoples R China"
            }
        ],
        "venue": "JOURNAL OF INFORMATION SCIENCE AND ENGINEERING",
        "year": 2008
    },
    "1fSqy1xe": {
        "id": "1fSqy1xe",
        "title": "Batch Verifiable Computation with Public Verifiability for Outsourcing Polynomials and Matrix Computations.",
        "abstract": "In a verifiable computation VC scheme, a client asks a server to perform some outsourced computations, and the latter returns the results as its response. The results can be verified privately or publicly. Fiore and Gennaro CCS 2012 constructed publicly verifiable protocols for secure outsourcing polynomials and matrix computations. Batch verifiable computation BVC schemes allow a client to outsource multiple functions on a same input, and thus much reduce the storage overhead at the server side without sacrificing the efficiency of verification. However, existing BVC schemes only support private verifiability which only allows the client who outsources the computations to verify the results. In this paper, we propose BVC schemes with public verifiability, i.e., any third party can efficiently verify the results returned by the server without accessing secret key. To delegate s functions, our BVC schemes require a cloud storage of only $$1+1/s$$ times the storage size needed by the s functions themselves. We extend our schemes to meet less cloud storage overhead as well.",
        "keywords": "",
        "authors": [
            {
                "name": "Yujuan Sun",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            }
        ],
        "venue": "ACISP",
        "year": 2016
    },
    "1SI2K5Mx": {
        "id": "1SI2K5Mx",
        "title": "Effect of water activity and temperature on growth of Penicillium citreoviride and Penicillium citrinum on MiGao (rice cake).",
        "abstract": "Contamination by mold is a serious problem in steam-cooked rice cake, a traditional Chinese food. Growth responses to different temperatures and water activity values for Penicillium citreoviride and Penicillium citrinum, two of the most common molds, were investigated. Partial least square regression analysis showed that the growth of the two fungi did not differ in response to changes in water activity and temperature. Optimum water activity for growth was 0.90 and optimum temperatures for growth were 30 degrees C in most cases.",
        "keywords": [
            "rice cake",
            "temperature",
            "water activity",
            "penicillium citrinum",
            "penicillium citreoviride"
        ],
        "authors": [
            {
                "name": "Ying Ji",
                "org": "Southern Yangtze University(Southern Yangtze University),Wuxi,China"
            },
            {
                "name": "Kexue Zhu",
                "org": "Southern Yangtze University(Southern Yangtze University),Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Southern Yangtze University(Southern Yangtze University),Wuxi,China"
            },
            {
                "name": "Huiming Zhou",
                "org": "Southern Yangtze University(Southern Yangtze University),Wuxi,China"
            }
        ],
        "venue": "Canadian journal of microbiology",
        "year": 2007
    },
    "vYydJ8Se": {
        "id": "vYydJ8Se",
        "title": "Targeted separation of antibacterial peptide from protein hydrolysate of anchovy cooking wastewater by equilibrium dialysis.",
        "abstract": "Anchovy (Engraulis japonicus) cooking wastewater (ACWW) is a by-product resulted from the production of boiled-dried anchovies in the seafood processing industry. In this study, the protein hydrolysate of ACWW (ACWWPH) was found to have antimicrobial activity after enzymatic hydrolysis with Protamex. For the targeted screening of antibacterial peptides, liposomes constructed from Staphylococcus aureus membrane lipids were used in an equilibrium dialysis system. The hydrolysate was further purified by liposome equilibrium dialysis combined with high performance liquid chromatography. The purified antimicrobial peptide (ACWWP1) was determined to be GLSRLFTALK, with a molecular weight of 1104.6622Da. The peptide exhibited no haemolytic activity up to a concentration of 512μg/ml. It displayed a dose-dependent bactericidal effect in reconstituted milk. The change in cell surface hydrophobicity and membrane-permeable action of the purified ACWWP1 may have contributed to the antibacterial effect. This study suggests that liposome equilibrium dialysis can be used for the targeted screening of antimicrobial peptides.",
        "keywords": [
            "anchovy cooking wastewater",
            "antimicrobial peptide",
            "enzymatic hydrolysis",
            "equilibrium dialysis",
            "liposome"
        ],
        "authors": [
            {
                "name": "Wenting Tang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2015
    },
    "GMGDzoYt": {
        "id": "GMGDzoYt",
        "title": "Cryptanalysis and improvement of a block cipher based on multiple chaotic systems",
        "abstract": "Wang and Yu proposed a block cipher scheme based on dynamic sequences generated by multiple chaotic systems, which overcomes the problem of periodical degradation on random sequences due to computational precision. Their scheme has a feature that a plaintext is encrypted by a keystream created from several one-dimensional chaotic maps. However, this feature results in some weaknesses of the encryption algorithm. We show three kinds of attacks in this paper, through which one can recover the plaintext from a given ciphertext without the secret key. We also present an improvement on their scheme, which prevents the three attacks mentioned above. Security of the enhanced cipher is presented and analyzed, which shows that our improved scheme is secure under the current attacks. Copyright 2010 Jun He et al.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Jun He",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Yuan Zhou",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China(National Computer Network Emergency Response Technical Team,National Computer Network Emergency Response Technical Team/Coordination Center of China),Beijing,China"
            },
            {
                "name": "Zhibin Li",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            }
        ],
        "venue": "Mathematical Problems in Engineering",
        "year": 2010
    },
    "Pp5b1Kid": {
        "id": "Pp5b1Kid",
        "title": "Allelochemical stress causes oxidative damage and inhibition of photosynthesis in Chlorella vulgaris.",
        "abstract": "This study investigated the effects of N-phenyl-2-naphthylamine, an effective allelochemical on aquatic unicellular algae Chlorella vulgaris at physiological gene transcription level. Exposure to 2.5 mg L(-1) of N-phenyl-2-naphthylamine increased the activities of the antioxidant enzymes, superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT), which were 2.47, 3.24, and 4.27 times higher than that of the control, however, exposure to 4.0 mg L(-1) N-phenyl-2-naphthylamine decreased the activities of these antioxidant enzymes. An increase in malondialdehyde content and a decrease in chlorophyll content following exposure to N-phenyl-2-naphthylamine suggested that the alga was severely damaged and that cell growth was greatly inhibited. Electron microscopy showed that the plasma membrane was detached from the cell wall, the nucleus was condensed, and the structure of chloroplasts was disrupted, in response to N-phenyl-2-naphthylamine exposure. Real-time PCR showed that N-phenyl-2-naphthylamine reduced the transcript abundance of psaB and psbC to 3% and 1% of the control, respectively. These results demonstrated that N-phenyl-2-naphthylamine not only inhibited photosynthesis, but also triggered the synthesis of reactive oxygen species (ROS) to disrupt the subcellular structure of this aquatic organism.",
        "keywords": [
            "allelochemical",
            "n-phenyl-2-naphthylamine",
            "real-time pcr",
            "chlorella vulgaris",
            "electron microscopy"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Xiaoyan Xu",
                "org": ""
            },
            {
                "name": "Wei Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Hong Jiang",
                "org": "Ministry of Education, Key Lab of Environment Remediation and Ecological Health, College of Environmental and Resource, Zhejiang University, Hangzhou 310029, People’s Republic of China"
            },
            {
                "name": "Yuanxiang Jin",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Chemosphere",
        "year": 2009
    },
    "6EfUH9Yu": {
        "id": "6EfUH9Yu",
        "title": "Aquatic ecotoxicity of an antidepressant, sertraline hydrochloride, on microbial communities.",
        "abstract": "Sertraline hydrochloride (Ser-HCl), a widely used antidepressant, becomes an aquatic contaminant via metabolic excretion and improper disposal; however, it is unknown how Ser-HCl affects aquatic microbial communities. The present study investigated the effects of Ser on the structures of aquatic microbial communities via high-throughput sequencing analyses. Ser-HCl treatment inhibited the growth of two model algae (the green alga, Chlorella vulgaris, and the cyanobacterium, Microcystis aeruginosa) and decreased the chlorophyll a (Chl-a) concentration in the microcosm to reduce the photosynthetic efficiency. High-throughput sequencing analyses showed that exposure to Ser-HCl disturbed the balance of cyanobacteria species by stimulating the growth of specific cyanobacteria. Among eukaryotes, the richness as well as the diversity indices were significantly enhanced after 5 days of Ser-HCl treatment but sharply decreased with exposure time. Nucleariida occupied an absolute majority (97.83%) within the eukaryotes, implicating that Ser-HCl disturbed the ecological equilibrium in microcosms. Ser-HCl will continue to be an environmental contaminant due to its wide usage and production. Our current study clarified the potential ecological risk of Ser-HCl to aquatic microorganisms. These findings suggest that more attention should be given to the negative effects of these bioactive pollutants on aquatic environments.",
        "keywords": [
            "Antidepressants",
            "Cyanobacteria",
            "Ecotoxicity",
            "Microbial community",
            "Sertraline hydrochloride"
        ],
        "authors": [
            {
                "name": "Zhaopeng Yang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "VWlesD3z": {
        "id": "VWlesD3z",
        "title": "Privacy-Preserving Public Auditing Protocol for Low-Performance End Devices in Cloud.",
        "abstract": "Cloud storage provides tremendous storage resources for both individual and enterprise users. In a cloud storage system, the data owned by a user are no longer possessed locally. Hence, it is not competent to ensure the integrity of the outsourced data using traditional data integrity checking methods. A privacy-preserving public auditing protocol allows a third party auditor to check the integrity of the outsourced data on behalf of the users without violating the privacy of the data. However, existing privacy-preserving public auditing protocols assume that the end devices of users are powerful enough to compute all costly operations in real time when the data to be outsourced are given. In fact, the end devices may also be those with low computation capabilities. In this paper, we propose two lightweight privacy-preserving public auditing protocols. Our protocols are based on online/offline signatures, by which an end device only needs to perform lightweight computations when a file to be outsourced is available. Besides, our proposals support batch auditing and data dynamics. Experiments show that our protocols are hundreds of times more efficient than a recent proposal regarding to the computational overhead on user side.",
        "keywords": [
            "Protocols",
            "Cloud computing",
            "Performance evaluation",
            "Data privacy",
            "Security",
            "Proposals",
            "Systems architecture"
        ],
        "authors": [
            {
                "name": "Jiangtao Li",
                "org": "Shanghai Key Laboratory of Trustworthy Computing, School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            },
            {
                "name": "Lei Zhang",
                "org": "Shanghai Key Laboratory of Trustworthy Computing, School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            },
            {
                "name": "Joseph K. Liu",
                "org": "Faculty of Information Technology, Monash University, Clayton, Australia"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Key Laboratory of Trustworthy Computing, School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            },
            {
                "name": "Zheming Dong",
                "org": "Shanghai Key Laboratory of Trustworthy Computing, School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "IEEE Trans. Information Forensics and Security",
        "year": 2016
    },
    "iQkK6LXk": {
        "id": "iQkK6LXk",
        "title": "Evaluation of Hunter color values L, a, and b of mixed powder",
        "abstract": "",
        "keywords": [
            "hunter color value",
            "linear relation",
            "mass percent",
            "mixed powder"
        ],
        "authors": [
            {
                "name": "Kerui Zhu",
                "org": ""
            },
            {
                "name": "Philip John Kanu",
                "org": ""
            },
            {
                "name": "Irakoze Pierre Claver",
                "org": ""
            },
            {
                "name": "Xia Wang",
                "org": ""
            },
            {
                "name": "Kexue Zhu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Huiming Zhou",
                "org": ""
            }
        ],
        "venue": "Color Research and Application",
        "year": 2010
    },
    "Y0Udy1Qk": {
        "id": "Y0Udy1Qk",
        "title": "Reproductive and endocrine-disrupting toxicity of Microcystis aeruginosa in female zebrafish.",
        "abstract": "Microcystis aeruginosa, a primary species in cyanobacterial blooms, is ubiquitously distributed in water. Microcystins (MCs) purified from M. aeruginosa can exert reproductive toxicity in fish. However, the effects of M. aeruginosa at environmentally relevant levels on the reproductive and endocrine systems of zebrafish are still unknown. The present study investigated the reproductive and endocrine-disrupting toxicity of M. aeruginosa on female zebrafish (Danio rerio) by short-term exposure (96 h). After exposure, marked histological lesions in the liver or gonads, such as nuclear pyknosis and deformation, were observed, and the fertilization rate and hatchability of eggs spawned from treated females were both significantly lower than they were in females in the control group, suggesting the possibility of transgenerational effects of M. aeruginosa exposure. Moreover, M. aeruginosa exposure decreased the concentration of 17β-estradiol (E2) and testosterone (T) in female zebrafish. Interestingly, the vtg1 transcriptional level significantly decreased in the liver, whereas plasma vitellogenin (VTG) protein levels increased. The present findings indicate that M. aeruginosa could modulate endocrine function by disrupting transcription of hypothalamic-pituitary-gonadal-liver (HPGL) axis-related genes, and impair the reproductive capacity of female zebrafish, suggesting that M. aeruginosa causes potential adverse effects on fish reproduction in Microcystis bloom-contaminated aquatic environments.",
        "keywords": [
            "Endocrine-disruption",
            "Microcystis aeruginosa",
            "Reproductive toxicity",
            "Zebrafish"
        ],
        "authors": [
            {
                "name": "Guangfu Liu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China; Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: sunliwei@zjut.edu.cn."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Chemosphere",
        "year": 2018
    },
    "yz28D5B6": {
        "id": "yz28D5B6",
        "title": "Unleash the Power for Tensor: A Hybrid Malware Detection System Using Ensemble Classifiers.",
        "abstract": "The extensive growth of smartphones has spawned the propagation of malicious applications. Due to the increasing use of polymorphic malware, detection is becoming more difficult. To this end, ensemble learning has been proposed to improve accuracy in malware detection, without severely sacrificing time complexity. In this paper, we propose a hybrid detection system, TFBOOST, which incorporates the tensor filter algorithm into boosting ensemble generalization architecture, in order to improve detection efficacy. TFBOOST uses a static analysis to extract features and a level-by-level boosting structure with re-sampling process to diversify base learners. Experimental results show that TFBOOST generally outperforms state-of-the-art ensemble algorithms with higher detection precision and lower false positive rates. Finally, we visually interpret the high-level results of TFBOOST and conjecture that repackaged malware is the mainstay of potential malware.",
        "keywords": "",
        "authors": [
            {
                "name": "Jieqiong Hou",
                "org": ""
            },
            {
                "name": "Minhui Xue",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University"
            }
        ],
        "venue": "ISPA/IUCC",
        "year": 2017
    },
    "JnTttKhI": {
        "id": "JnTttKhI",
        "title": "Proteomic analysis of the hepatotoxicity of Microcystis aeruginosa in adult zebrafish (Danio rerio) and its potential mechanisms.",
        "abstract": "Microcystis aeruginosa is one of the main species of cyanobacteria that causes water blooms. M. aeruginosa can release into the water several types of microcystins (MCs), which are harmful to aquatic organisms and even humans. However, few studies have investigated the hepatotoxicity of M. aeruginosa itself in zebrafish in environments that simulate natural aquatic systems. The objective of this study was to evaluate the hepatotoxicity of M. aeruginosa in adult zebrafish (Danio rerio) after short-term (96 h) exposure and to elucidate the potential underlying mechanisms. Distinct histological changes in the liver, such as enlargement of the peripheral nuclei and sinusoids and the appearance of fibroblasts, were observed in zebrafish grown in M. aeruginosa culture. In addition, antioxidant enzyme activity was activated and protein phosphatase (PP) activity was significantly decreased with increasing microalgal density. A proteomic analysis revealed alterations in a number of protein pathways, including ribosome translation, immune response, energy metabolism and oxidative phosphorylation pathways. Western blot and real-time PCR analyses confirmed the results of the proteomic analysis. All results indicated that M. aeruginosa could disrupt hepatic functions in adult zebrafish, thus highlighting the necessity of ecotoxicity assessments for M. aeruginosa at environmentally relevant densities.",
        "keywords": [
            "Gene expression",
            "Hepatotoxicity",
            "Microcystis aeruginosa",
            "Proteomic",
            "Western blot",
            "Zebrafish"
        ],
        "authors": [
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Guangfu Liu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Meng Zheng",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2019
    },
    "w1YGBJwN": {
        "id": "w1YGBJwN",
        "title": "ESTABLISHMENT OF REAL-TIME PCR FOR ANALYZING mRNA ABUNDANCE IN <I>CHLORELLA VULGARIS</I> EXPOSED TO XENOBIOTICS: ESTABLISHMENT OF REAL-TIME PCR FOR ANALYZING mRNA ABUNDANCE IN <I>CHLORELLA VULGARIS</I> EXPOSED TO XENOBIOTICS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xiao-Yan XU",
                "org": ""
            },
            {
                "name": "Hai-Feng QIAN",
                "org": ""
            },
            {
                "name": "Wei CHEN",
                "org": ""
            },
            {
                "name": "Hong JIANG",
                "org": ""
            },
            {
                "name": "Zheng-Wei FU",
                "org": ""
            }
        ],
        "venue": "Acta Hydrobiologica Sinica",
        "year": 2010
    },
    "1zuQR6LM": {
        "id": "1zuQR6LM",
        "title": "Ecological Effects of Single-Walled Carbon Nanotubes on Soil Microbial Communities and Soil Fertility.",
        "abstract": "The manufacturers of single-walled carbon nanotubes (SWCNTs) are continuously expanding their manufacturing and commercial markets, indicating that the environmental release and accumulation of SWCNTs in soil is inevitable. However, little is known about the effects of SWCNTs on soil physicochemical properties and soil microbial communities. Our results showed that treatment with SWCNTs resulted in an enhancement of microorganism metabolism related to soil organic compound degradation and a change in the structure of soil microbial communities, but the diversity of soil microorganisms was not significantly affected. The decrease in soil urease activity and the increase in the relative abundance of Nitrospirae after SWCNTs exposure might be relevant to the induction of soil nitrification. The relative abundances of phosphate-solubilizing microorganisms increased after exposure to SWCNTs, which was beneficial for phosphorus bioavailability in the soil. Our current study highlights that exposure to SWCNTs at concentrations of 3 and 10 µg/g can change the composition of soil microorganism communities, promote soil organic degradation and improve soil fertility by enhancing N and P availability in a short time.",
        "keywords": [
            "Illumina sequencing analysis",
            "Single-walled carbon nanotubes (SWCNTs)",
            "Soil enzyme activity",
            "Soil microbial communities"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China. hfqian@zjut.edu.cn."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xingxing Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2018
    },
    "PfWwO8RB": {
        "id": "PfWwO8RB",
        "title": "An information-theoretic framework for optimal temperature sensor allocation and full-chip thermal monitoring",
        "abstract": "Full-chip thermal monitoring is an important and challenging issue in today's microprocessor design. In this paper, we propose a new information-theoretic framework to quantitatively model the uncertainty of on-chip temperature variation by differential entropy. Based on this framework, an efficient optimization scheme is developed to find the optimal spatial locations for temperature sensors such that the full-chip thermal map can be accurately captured with a minimum number of on-chip sensors. In addition, several efficient numerical algorithms are proposed to minimize the computational cost of the proposed entropy calculation and optimization. As will be demonstrated by our experimental examples, the proposed entropy-based method achieves superior accuracy (1.4x error reduction) for full-chip thermal monitoring over prior art.",
        "keywords": [
            "efficient optimization scheme",
            "optimal temperature sensor allocation",
            "proposed entropy-based method",
            "differential entropy",
            "full-chip thermal monitoring",
            "on-chip temperature variation",
            "on-chip sensor",
            "efficient numerical algorithm",
            "proposed entropy calculation",
            "new information-theoretic framework",
            "full-chip thermal map",
            "chip",
            "integrated circuit design",
            "integrated circuit",
            "random variables",
            "temperature measurement",
            "numerical analysis",
            "vectors",
            "entropy"
        ],
        "authors": [
            {
                "name": "Huapeng Zhou",
                "org": "Carnegie Mellon University, Pittsburgh, PA"
            },
            {
                "name": "Xin Li",
                "org": "Carnegie Mellon University, Pittsburgh, PA"
            },
            {
                "name": "Chen-Yong Cher",
                "org": "IBM T. J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Eren Kursun",
                "org": "IBM T. J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Haifeng Qian",
                "org": "IBM T. J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Shi-Chune Yao",
                "org": "Carnegie Mellon University, Pittsburgh, PA"
            }
        ],
        "venue": "DAC",
        "year": 2012
    },
    "j1Z4tZip": {
        "id": "j1Z4tZip",
        "title": "Fully-secure and practical sanitizable signatures",
        "abstract": "Sanitizable signatures have been introduced recently to provide a means for the signer to authorize a censor to modify some parts of the signed message without the help of the original signer. This paper presents the following three contributions. (1) We point out the weaknesses of Brzuska et al.'s (PKC 2009) and Canard et al.'s (CT-RSA 2010) constructions respectively. Namely we show that their constructions are not signer-accountable. (2) We point out the weakness of Brzuska et al.'s security model (PKC 2009) for sanitizable signatures by showing some potential attacks neglected in their original model. (3) We present a stronger security model based on Brzuska et al.'s model and a fullysecure construction based on both Brzuska et al.'s and Canard et al.'s constructions. We must note that our proposed construction is much more practical than prior ones. In detail, the computation costs of signing, sanitizing and verification algorithm are constant and the signature size is constant as well.",
        "keywords": [
            "fullysecure construction",
            "practical sanitizable signature",
            "potential attack",
            "stronger security model",
            "signature size",
            "original model",
            "sanitizable signature",
            "computation cost",
            "security model",
            "original signer",
            "proposed construction",
            "provable security"
        ],
        "authors": [
            {
                "name": "Junqing Gong",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Yuan Zhou",
                "org": "Network Emergency Response Technical Team, Coordination Center, China"
            }
        ],
        "venue": "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
        "year": 2011
    },
    "SYO964qr": {
        "id": "SYO964qr",
        "title": "A Proximity Measure using Blink Model.",
        "abstract": "This paper proposes a new graph proximity measure. This measure is a derivative of network reliability. By analyzing its properties and comparing it against other proximity measures through graph examples, we demonstrate that it is more consistent with human intuition than competitors. A new deterministic algorithm is developed to approximate this measure with practical complexity. Empirical evaluation by two link prediction benchmarks, one in coauthorship networks and one in Wikipedia, shows promising results. For example, a single parameterization of this measure achieves accuracies that are 14-35% above the best accuracy for each graph of all predictors reported in the 2007 Liben-Nowell and Kleinberg survey.",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Hui Wan",
                "org": ""
            },
            {
                "name": "Mark N. Wegman",
                "org": ""
            },
            {
                "name": "Luis A. Lastras",
                "org": ""
            },
            {
                "name": "Ruchir Puri",
                "org": ""
            }
        ],
        "venue": "arXiv: Social and Information Networks",
        "year": 2016
    },
    "YSMXRse2": {
        "id": "YSMXRse2",
        "title": "Sesame Protein 11: Functional Properties of Sesame (Sesamum indicum L.) Protein Isolate as Influenced by pH, Temperature, Time and Ratio of Flour to Water During its Production",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ming zhou",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "kexue zhu",
                "org": ""
            }
        ],
        "venue": "Asian Journal of Biochemistry",
        "year": 2007
    },
    "H8bAf2fS": {
        "id": "H8bAf2fS",
        "title": "The effect of exogenous nitric oxide on alleviating herbicide damage in Chlorella vulgaris.",
        "abstract": "Herbicides present in the environment induce oxidative stress in plants. We investigated the roles of exogenous NO-regulated chlorophyll synthesis, antioxidant enzyme activity and gene expression in herbicide-treated unicellular green algae Chlorella vulgaris. Atrazine (100 microg/L) or glufosinate (10 mg/L) treatment alone or in combination with 20 microM sodium nitroprussiate (SNP, 10 microM with glufosinate) was administered to algae for a short time period of 48 h to observe changes in physiology and gene transcription and expression. Supplementation of atrazine or glufosinate with low SNP significantly reduced H2O2, reactive oxygen species (ROS) and malondialdehyde (MDA) induction by herbicides. Supplementation also increased chlorophyll content and antioxidant enzymes, superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activity, as compared to herbicide treatment alone. This trend suggests an effect of NO on the scavenging of ROS. Furthermore, the expression of photosynthesis genes (psbC, psaB, chlB and rbcL) was also upregulated by supplementation of low SNP, thus maintaining the normal photosynthetic function. However, high concentration of SNP (100 microM) in combination with herbicides aggravated damage to algae, including increases in H2O2, ROS and MDA and decreases in chlorophyll content, antioxidant enzyme activity and photosynthesis genes transcription. 2-Phenyl-4,4,5,5-tetramethyl-imidazoline-1-oxyl-3-oxide (PTIO), the NO scavenger, was also examined in this study; the results showed that PTIO could neutralise the effect of low SNP. Data also showed that an exogenous supply of NO protects Chlorella vulgaris against the toxicity of herbicides by protecting against oxidant substances and increasing the transcription of related genes.",
        "keywords": [
            "gene expression",
            "snp",
            "herbicide",
            "nitric oxide",
            "oxidative stress",
            "peroxidase",
            "gene transcription",
            "aquatic plants",
            "enzyme activity",
            "photosynthesis",
            "hydrogen peroxide",
            "transcription",
            "genes",
            "enzymes",
            "biosynthesis"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Wei Chen",
                "org": ""
            },
            {
                "name": "Jingjing Li",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Jie Wang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Zhen Zhou",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Weiping Liu",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Aquatic toxicology (Amsterdam, Netherlands)",
        "year": 2009
    },
    "h3VcdT8k": {
        "id": "h3VcdT8k",
        "title": "Practical and Efficient Attribute-Based Encryption with Constant-Size Ciphertexts in Outsourced Verifiable Computation.",
        "abstract": "In cloud computing, computationally weak users are always willing to outsource costly computations to a cloud, and at the same time they need to check the correctness of the result provided by the cloud. Such activities motivate the occurrence of verifiable computation (VC). Recently, Parno, Raykova and Vaikuntanathan showed any VC protocol can be constructed from an attribute-based encryption (ABE) scheme for a same class of functions. In this paper, we propose two practical and efficient semi-adaptively secure key-policy attribute-based encryption (KP-ABE) schemes with constant-size ciphertexts. The semi-adaptive security requires that the adversary designates the challenge attribute set after it receives public parameters but before it issues any secret key query, which is stronger than selective security guarantee. Our first construction deals with small universe while the second one supports large universe. Both constructions employ the technique underlying the prime-order instantiation of nested dual system groups, which are based on the $d$-linear assumption including SXDH and DLIN assumptions. In order to evaluate the performance, we implement our ABE schemes using $\\\\textsf{Python}$ language in Charm. Compared with previous KP-ABE schemes with constant-size ciphertexts, our constructions achieve shorter ciphertext and secret key sizes, and require low computation costs, especially under the SXDH assumption.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Junqing Gong",
                "org": ""
            },
            {
                "name": "Shaohua Tang",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Zhenfu Cao",
                "org": ""
            }
        ],
        "venue": "AsiaCCS",
        "year": 2016
    },
    "iryf4XbV": {
        "id": "iryf4XbV",
        "title": "Malicious activity detection of a functional unit",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "chenyong cher",
                "org": ""
            },
            {
                "name": "eren kursun",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "d8Ygw5GC": {
        "id": "d8Ygw5GC",
        "title": "Cryptanalysis of new digital nominative proxy signature schemes for mobile communication",
        "abstract": "Recently, Park and Lee proposed a digital nominative proxy signature scheme for mobile communication. Seo and Sun pointed out that Park and Lee's scheme can't resist the forgery attack from the original signer. To provide the unforgeablity and nonrepudiation, Seo et al also proposed a new nominative proxy signature scheme for mobile communication. However, in the paper, we show that the new scheme can't satisfy the non-repudiation among their security requirement either. Based on Seo et al's scheme, an improved scheme is proposed. The improved scheme can resist not only the attack mentioned in Seo and Sun's schemes, but also the attack proposed by us to Seo et al's scheme. Also, the improved version retains the advantages of Seo et al's scheme. In addition, we discuss one of basic principles of design of proxy-protected signature schemes based on DLP (discrete logarithm problem).",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Qingshui Xue",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            }
        ],
        "venue": "Proceedings - 2004 Global Mobile Congress",
        "year": 2004
    },
    "fuoGts1E": {
        "id": "fuoGts1E",
        "title": "Effects of copper sulfate, hydrogen peroxide and N-phenyl-2-naphthylamine on oxidative stress and the expression of genes involved photosynthesis and microcystin disposition in Microcystis aeruginosa.",
        "abstract": "Algal blooms have been increasing in prevalence all over the world, destroying ecosystems and placing other organisms at risk. Chemical remediation is one of most important methods of controlling algal bloom formation. The effects of copper sulfate, hydrogen peroxide (H(2)O(2)) and N-phenyl-2-naphthylamine on photosynthesis-related and microcystin-related gene transcription and physiological changes of Microcystis aeruginosa were analyzed. The results suggest that transcription of psaB, psbD1 and rbcL was inhibited by the three algaecides, which blocked the electron transport chain, significantly enhanced reactive oxygen species (ROS) accumulation and overwhelmed the antioxidant system. The increase in ROS destroyed pigment synthesis and membrane integrity, which inhibited or killed the algal cells. Furthermore, H(2)O(2) treatment down-regulated mcyD transcription, which indicated a decrease in the microcystin level in the cells. Our results demonstrate that H(2)O(2) has the greatest potential as an algaecide because it not only inhibits algae growth but may reduce microcystin synthesis.",
        "keywords": [
            "toxicity",
            "microcystis aeruginosa",
            "pna",
            "h 2 o 2",
            "cuso 4",
            "gene transcription",
            "algal bloom",
            "electron transport chain",
            "hydrogen peroxide"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310032, China"
            },
            {
                "name": "Shuqiong Yu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310032, China"
            },
            {
                "name": "Zhengqi Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310032, China"
            },
            {
                "name": "Xiucai Xie",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310032, China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang, 310032, China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Aquatic toxicology (Amsterdam, Netherlands)",
        "year": 2010
    },
    "dWfcy1OL": {
        "id": "dWfcy1OL",
        "title": "An antimicrobial peptide screened from casein hydrolyzate by Saccharomyces cerevisiae cell membrane affinity method",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wenting tang",
                "org": ""
            },
            {
                "name": "huaning yuan",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            }
        ],
        "venue": "Food Control",
        "year": 2015
    },
    "BgtcRCC6": {
        "id": "BgtcRCC6",
        "title": "Enantioselective phytotoxicity of the herbicide imazethapyr in rice.",
        "abstract": "Research increasingly suggests that enantiomer selectivity may be a part of the toxicological effects of chiral contaminants. In this study, we selected Japonica rice variety Xiushui 63 seedlings to evaluate the enantioselectivity of imazethapyr (IM). Significant differences in rice seedling morphology, antioxidant enzyme, oxidant marker and gene transcription were observed between the two IM enantiomers. In the seedling morphological assay, IM enantiomers inhibited elongation of primary roots and shoots, and reduced the number of adventitious roots and the density of root hairs. The inhibitory effects were enhanced with increasing concentrations of IM. The maximal root relative inhibition rate reached 80.4%, 67.0%, and 73.5% for R-(-)-IM, S-(+)-IM and racemate at the concentration of 0.5 mg L(-1), respectively, and the maximal shoot relative inhibition rate reached 77.7%, 26.9%, and 61.7%, respectively. The activities of SOD, POD and CAT and the content of MDA increased at 0.5 mg L(-1) of R-(-)-IM treatment, and were 1.8, 3.3, 1.4, and 2.2 times, respectively, over the activities S-(+)-IM. Real-time PCR showed that R-(-)-IM minimized the transcript abundance of ALS in shoot tissue to 12.2% of the S-(+)-IM, and minimized the transcript abundance of PC in seed to 9.2% of the S-(+)-IM. R-(-)-IM maximized the transcript abundance of beta-amylase in shoots to 8.6-time of the S-(+)-IM. Results from this study imply that R-(-)-IM has stronger toxicity on the growth of rice than S-(+)-IM.",
        "keywords": [
            "enantioselectivity",
            "gene transcription",
            "imazethapyr",
            "rice"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Haijia Hu",
                "org": ""
            },
            {
                "name": "Yuanyuan Mao",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Jian Ma",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Anping Zhang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People’s Republic of China"
            },
            {
                "name": "Weiping Liu",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Chemosphere",
        "year": 2009
    },
    "n6MgSsjk": {
        "id": "n6MgSsjk",
        "title": "FinExpert - domain-specific test generation for FinTech systems.",
        "abstract": "To assure high quality of software systems, the comprehensiveness of the created test suite and efficiency of the adopted testing process are highly crucial, especially in the FinTech industry, due to a FinTech system’s complicated system logic, mission-critical nature, and large test suite. However, the state of the testing practice in the FinTech industry still heavily relies on manual efforts. Our recent research efforts contributed our previous approach as the first attempt to automate the testing process in China Foreign Exchange Trade System (CFETS) Information Technology Co. Ltd., a subsidiary of China’s Central Bank that provides China’s foreign exchange transactions, and revealed that automating test generation for such complex trading platform could help alleviate some of these manual efforts. In this paper, we investigate further the dilemmas faced in testing the CFETS trading platform, identify the importance of domain knowledge in its testing process, and propose a new approach of domain-specific test generation to further improve the effectiveness and efficiency of our previous approach in industrial settings. We also present findings of our empirical studies of conducting domain-specific testing on subsystems of the CFETS Trading Platform.\n\n",
        "keywords": "",
        "authors": [
            {
                "name": "Tiancheng Jin",
                "org": "East China Normal University, China"
            },
            {
                "name": "Qingshun Wang",
                "org": "East China Normal University, China"
            },
            {
                "name": "Lihua Xu",
                "org": "New York University Shanghai, China"
            },
            {
                "name": "Chunmei Pan",
                "org": "CFETS Information Technology, China"
            },
            {
                "name": "Liang Dou",
                "org": "East China Normal University, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University, China"
            },
            {
                "name": "Liang He",
                "org": "East China Normal University, China"
            },
            {
                "name": "Tao Xie",
                "org": "University of Illinois at Urbana-Champaign, USA"
            }
        ],
        "venue": "ESEC/SIGSOFT FSE",
        "year": 2019
    },
    "AXvVw7VH": {
        "id": "AXvVw7VH",
        "title": "DESIGNING A ROBUST POWER EFFICIENT CLOCK DISTRIBUTION NETWORK",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "charles j alpert",
                "org": ""
            },
            {
                "name": "joseph n kozhaya",
                "org": ""
            },
            {
                "name": "zhuo li",
                "org": ""
            },
            {
                "name": "joseph j palumbo",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "phillip j restle",
                "org": ""
            },
            {
                "name": "chin ngai sze",
                "org": ""
            },
            {
                "name": "ying zhou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "XQ0W4Pbh": {
        "id": "XQ0W4Pbh",
        "title": "Phytotoxic effects of silver nanoparticles and silver ions to Arabidopsis thaliana as revealed by analysis of molecular responses and of metabolic pathways.",
        "abstract": "The acute (3 days) and chronic (whole life history) responses of Arabidopsis thaliana following exposure to silver nanoparticles (AgNPs) and Ag ions (AgNO) in respectively a hydroponic medium and in soil were studied. After 3 days of hydroponic exposure, AgNPs (1.0 and 2.5 mg/L) exerted more severe inhibitory effects on plant (shoot and root) growth and photosynthesis than the same concentrations of Ag ions. In soil cultivation, the photoperiod, the autonomous, and the vernalization pathways were down-regulated to 0.15- to 0.5-fold of the control after 12.5 mg/kg AgNPs treatment. This exposure caused a decrease of approximately 25%-40% as compared to the control of the transcription of flowering key genes including AP1, LFY, FT and SOC1, and finally resulted in a delayed flowering time of 5 days. Only autonomous and vernalization pathways were inhibited by Ag ion treatment and ultimately the time of flowering in treated plants was delayed by 3 days. The energy production related metabolic pathways in the tricarboxylic acid cycle and in sugar metabolism were stimulated stronger by AgNPs than by Ag ion treatment, thus releasing more energy and accelerating the physiological metabolic responses against stress in the AgNPs treatment while subsequently reducing the plant growth and yield at the maturation stage. Importantly, shikimate-phenylpropanoid biosynthesis, and tryptophan and galactose metabolisms were regulated only by the AgNPs treatment, which was a specific effect of nanoparticles. This work provides a systematic understanding at the molecular, physiological as well as metabolic level of the effects of AgNPs and Ag ions in A. thaliana.",
        "keywords": [
            "Arabidopsis thaliana",
            "Flowering time",
            "Metabolic profiling",
            "Silver nanoparticles",
            "Toxicity"
        ],
        "authors": [
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300 RA Leiden, The Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, The Netherlands."
            },
            {
                "name": "Xingxing Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "933voLdR": {
        "id": "933voLdR",
        "title": "Effects of residual S-metolachlor in soil on the phyllosphere microbial communities of wheat (Triticum aestivum L.).",
        "abstract": "S-metolachlor (S-ME) is a widely used chiral herbicide that can cause potential ecological risks via long-term usage. In this work, we chose a model plant, wheat, as the test material to determine the effects of applying 10 mg/kg S-ME to soil on its fresh weight, chlorophyll and malondialdehyde (MDA) content, and superoxide dismutase (SOD) activity and the diversity and structural composition of the phyllosphere microorganisms after 7 and 14 days of exposure. Our work showed that this concentration of residual S-ME in soil only slightly decreased plant biomass and had little effect on lipid peroxidation, the antioxidant enzyme system and chlorophyll content. Interestingly, although the test concentration of S-ME did not exert strong inhibitory effects on the physiological activities of wheat, it decreased the diversity of phyllosphere microbial communities and changed their structure, indicating that microorganisms were more sensitive stress indicators. S-ME reduced the colonization by some beneficial bacteria related to plant nitrogen fixation among the phyllosphere microorganisms, which influenced the growth and yield of wheat because these bacteria contribute to plant fitness. In addition, S-ME affected the association between the host and the composition of the phyllosphere microbial communities under different growth conditions. Our work provides insights into the ecological implications of the effects of herbicides on the phyllosphere microbiome.",
        "keywords": [
            "Chiral herbicides",
            "Microbial ecotoxicity",
            "Phyllosphere microorganism",
            "S-metolachlor",
            "Wheat"
        ],
        "authors": [
            {
                "name": "Nuohan Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Wenting Yuan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hengzheng Cui",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yijia Shen",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Wei Lin",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2020
    },
    "t5aFmejU": {
        "id": "t5aFmejU",
        "title": "In vitro and in vivo antioxidant activity of polyphenols extracted from black highland barley.",
        "abstract": "The objective of this study was to determine the antioxidant capacity of polyphenols extracted from black highland barley (BHLPE) in vitro and in vivo. BHLPE was found to have strong superoxide radical, hydroxyl radical and 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, ferric reducing antioxidant power and moderate metal ion-chelating activity. Compared with a high fat diet (HFD) group, mice that were administered 600mg BHLPE/kg body weight showed significant decreases in total cholesterol, low-density lipoprotein cholesterol and the atherosclerosis index, in addition to markedly increased high-density lipoprotein cholesterol levels. Furthermore, the antioxidant defense system and antioxidant gene expression were significantly improved in vivo in mice that were administered BHLPE compared with mice in the HFD group. These results suggest that BHLPE has significant potential as a natural antioxidant to promote health and to reduce the risk of disease.",
        "keywords": [
            "Antioxidant activity",
            "Black highland barley",
            "In vitro",
            "In vivo",
            "Oxidative stress"
        ],
        "authors": [
            {
                "name": "Yingbin Shen",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            },
            {
                "name": "Liling Cheng",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2016
    },
    "WyPbaa4l": {
        "id": "WyPbaa4l",
        "title": "MANET IP Allocation Method Based on Buddy Chain",
        "abstract": "Aiming at the problems in IP allocation in MANET,this paper brings up the buddy-chain system which takes the advantage of binary tree with a weighted approach to gracefully overcome the difficulties in IP recirculation and uneven IP allocation of MANET.It proves the evenness by analyzing the relationship between a single node and its neighbors while studying the robustness through a statistical model for the number of on-line nodes in unit time.It evaluates the communication cost and the outcome is O(21/n)～O(lb(n)×21/n).",
        "keywords": [
            "buddy chain",
            "MANET IP allocation",
            "security",
            "efficiency"
        ],
        "authors": [
            {
                "name": "XU Qi",
                "org": "Institute of Information,East China Normal University,Shanghai ,China"
            },
            {
                "name": "ZHANG Wei",
                "org": "Institute of Information,East China Normal University,Shanghai ,China"
            },
            {
                "name": "ZHOU Yuan",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China,Beijing ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Institute of Information,East China Normal University,Shanghai ,China"
            }
        ],
        "venue": "Computer Engineering",
        "year": 2010
    },
    "YsF9msrS": {
        "id": "YsF9msrS",
        "title": "Effect of salicylic acid on fatty acid accumulation in  during stationary growth phase",
        "abstract": "Microalgae possess great potential for use as raw materials for biofuel production. The marine diatom  accumulates lipids as its major form of energy storage when grown under specific conditions. This study investigated the effects of salicylic acid (SA) on the accumulation of fatty acids in  in the stationary growth phase. Our results showed that 40 μM SA increased the total fatty acid content accumulation 1.3-fold of the control after 4 days of exposure. The metabolomics data indicated that SA stimulated the fatty acid monostearin, 2-monoolein, monoolein, and methyl palmitoleate to 22.7-, 16.3-, 3.47-, and 3.47-fold of the control, respectively. The results of physiological and gene transcriptional levels revealed that the glycolysis, N assimilation, and fatty acid synthesis pathways were induced by SA treatment and thus accelerated fatty acid synthesis from carbohydrate and N compounds. The SA treatment could be used to optimize biodiesel production.",
        "keywords": [
            "Phaeodactylum tricornutum",
            "Lipid",
            "Salicylic acid",
            "Metabonomics"
        ],
        "authors": [
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xingxing Li",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Guanfu Liu",
                "org": "Department of Food Science and Technology,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Journal of Applied Phycology",
        "year": 2017
    },
    "47ylL0R1": {
        "id": "47ylL0R1",
        "title": "Early radiometric calibration performances of GOES-16 advanced baseline imager.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Boryana Efremova",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Bob Iacovazzi",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2017
    },
    "NWduHfSG": {
        "id": "NWduHfSG",
        "title": "Physical, Functional, and Sensory Characteristics of Cereal Extrudates",
        "abstract": "",
        "keywords": [
            "sensory",
            "functional"
        ],
        "authors": [
            {
                "name": "caike zhang",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "International Journal of Food Properties",
        "year": 2013
    },
    "rjfIrw1P": {
        "id": "rjfIrw1P",
        "title": "TPP and TCEP induce oxidative stress and alter steroidogenesis in TM3 Leydig cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "guanliang chen",
                "org": ""
            },
            {
                "name": "songbin zhang",
                "org": ""
            },
            {
                "name": "yuanxiang jin",
                "org": ""
            },
            {
                "name": "yan wu",
                "org": ""
            },
            {
                "name": "ling liu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            }
        ],
        "venue": "Reproductive Toxicology",
        "year": 2015
    },
    "BONW2jIY": {
        "id": "BONW2jIY",
        "title": "Signcryption KEM/tag-KEM, revisited",
        "abstract": "We revisit the problem of basing signcryption SC tag key encapsulation mechanism KEM on standard assumptions and standard model and present direct constructions of SC-KEM/tag-KEM, which satisfy confidentiality and unforgeability with respect to adversarially chosen keys where the adversary is given more advantageous attack environment than existing models in the literature;are based on the standard decisional bilinear Diffie-Hellman and computational Diffie-Hellman assumptions without random oracle;do not use strongly unforgeable signature schemes as building blocks; andprovide comparable performance to existing SC-KEM/tag-KEM schemes.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Yu Yu",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, China"
            },
            {
                "name": "Jian Weng",
                "org": "Department of Computer Science, Jinan University, Guangzhou, China"
            },
            {
                "name": "Yuan Zhou",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2015
    },
    "IHgBALth": {
        "id": "IHgBALth",
        "title": "Changes in bacterial community structure and antibiotic resistance genes in soil in the vicinity of a pharmaceutical factory.",
        "abstract": "China is the largest global producer of antibiotics. With the demand for antibiotics increasing every year, it is necessary to assess potential environmental risks and the spread of antibiotic resistance genes (ARGs) associated with antibiotic production. Here, we investigated the occurrence and distribution of ARGs in soil in the vicinity of a pharmaceutical factory. The results showed that antibiotic concentrations were under the detection limit; however, ARGs were present in soil and tended to be enriched near the factory. A significant correlation between the relative abundance of intI-1 and tetracycline ARGs implied that horizontal gene transfer might play an important role in the spread of ARGs. The occurrence of these ARGs could be the results of previous antibiotic contamination. However, the soil bacterial community structure seemed to be more affected by nutrients or other factors than by antibiotics. Overall, this study supports the viewpoint that long-term pharmaceutical activity might have a negative effect on environmental health, thus, underscoring the need to regulate antibiotic production and management.",
        "keywords": [
            "Antibiotic resistance genes",
            "Nutrients",
            "Pharmaceutical factory",
            "Soil bacterial community"
        ],
        "authors": [
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Jiahui Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR of China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2018
    },
    "knfPPFlQ": {
        "id": "knfPPFlQ",
        "title": "Efficient Non-interactive Deniable Authentication Protocols",
        "abstract": "Deniable authentication protocol is an authentication protocol that allows a sender to authenticate a message for a receiver, in a way that the receiver cannot convince a third party that such authentication ever took place. In recent years, due to the popularity of Internet and its special property, many deniable authentication protocols have been proposed. However, most of these proposed schemes are interactive and less efficient. To our knowledge, Shao has proposed an efficient non-interactive deniable authentication protocol based on generalized ElGamal signature scheme without security proof. Lu et al have proposed a deniable authentication also, however, the protocol suffers from the receiver's attack who once interacts with the sender. For the reason above, we would like to propose a generic method to construct efficient non-interactive deniable authentication protocols from any trapdoor permutations. Using RSA trapdoor permutations we introduce a new digital signature with tight security and use it to construct a concrete deniable authentication protocol. Concentrated on security problem we prove the protocol secure in random oracle. We also believe that the protocol is much efficient and practical in application with non-interactive property.",
        "keywords": [
            "authentication protocol",
            "security proof",
            "security problem",
            "non-interactive property",
            "deniable authentication",
            "proposed scheme",
            "tight security",
            "deniable authentication protocol",
            "efficient non-interactive deniable authentication",
            "concrete deniable authentication protocol",
            "digital signatures",
            "random oracle",
            "internet",
            "cryptography",
            "digital signature"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiao Tong University"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong University"
            },
            {
                "name": "Lichen Wang",
                "org": "Shanghai Jiao Tong University"
            },
            {
                "name": "Qingshui Xue",
                "org": "Shanghai Jiao Tong University"
            }
        ],
        "venue": "CIT",
        "year": 2005
    },
    "SuyNkrDd": {
        "id": "SuyNkrDd",
        "title": "On the design of broadbeam for massive MIMO systems",
        "abstract": "Massive MIMO has been identified as one of the promising disruptive air interface techniques to address the huge capacity requirement demanded by 5G wireless communications. For practical deployment of such systems, the control messages need to be broadcast to all users reliably in the cell using broadbeam. A perfect broadbeam is expected to have the same radiated power in all directions to cover users in any place in a cell. In this paper, we will show that there is no non-trivial solution for perfect broadbeam. Therefore, we develop a method for generating broadbeam that can allow tiny fluctuations in radiated power. Overall, this can serve as an ingredient for practical deployment of the massive MIMO systems.",
        "keywords": [],
        "authors": [
            {
                "name": "Deli Qiao",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Geoffrey Ye Li",
                "org": ""
            }
        ],
        "venue": "International Conference on Natural Computation",
        "year": 2016
    },
    "mbtgHsOA": {
        "id": "mbtgHsOA",
        "title": "Study of the migration and molecular structure of starch and protein in rice kernel during heating.",
        "abstract": "Leaching and re-absorption of leached solids and changes in kernel structure are of prime importance for the quality of cooked rice. This paper describes the contents and structural changes of both starch and protein in leached solids and rice kernels. Under actual cooking conditions, the leached solids increased with heating temperature and then decreased at specific temperatures relating gelatinization. Starch content of leached solids increased with the heating temperature, especially after gelatinization. As proteins are mainly distributed on the surface of the kernel, their release increased between 30 and 50 °C but then decreased with increasing leaching of starch at high temperatures. The molecular weight distribution of leached solids at different temperatures is significantly different, while it is similar in rice kernels. At 30-50 °C, the amylose contents in the leached solids were slightly higher than those in rice kernel, while the contents were similar at high temperatures. The transformation of the kernel structure during heating confirmed that the kernel surface and the formed cracks are the main path for leaching; the rearranged structures of the surface and cracks influence the final texture of cooked rice.",
        "keywords": [
            "Migration phenomena",
            "Molecular structures",
            "Protein",
            "Rice",
            "Starch"
        ],
        "authors": [
            {
                "name": "Ling Zhu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Shilin Bi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Bo Gong",
                "org": "Key Laboratory of Plant Functional Genomics of the Ministry of the Ministry of Education, Jiangsu Key Laboratory of Crop Genetics and Physiology, College of Agriculture, Yangzhou University, Yangzhou 225009, Jiangsu Province, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China. Electronic address: zhanghui@jiangnan.edu.cn."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2019
    },
    "lk5UWvR5": {
        "id": "lk5UWvR5",
        "title": "Privacy-Preserving Locally Weighted Linear Regression Over Encrypted Millions of Data.",
        "abstract": "The emerging development of cloud computing makes a trend that the cloud becomes a outsourced agglomeration for storing big data that generally contains numerous information. To mine the rich value involved in big data, the machine learning methodology is widespread employed due to its ability to adapt to data changes. However, the data mining process may involve the privacy issues of the users, hence they are reluctant to share their information. This is the reason why the outsourced data need to be dealt with securely, where data encryption is considered to be the most straightforward method to keep the privacy of data, but machine learning on the data in ciphertext domain is more complicated than the plaintext, since the relationship structure between data is no longer maintained, in such a way that we focus on the machine learning over encrypted big data. In this work, we study locally weighted linear regression (LWLR), a widely used classic machine learning algorithm in real-world, such as predict and find the best-fit curve through numerous data points. To tackle the privacy concerns in utilizing the LWLR algorithm, we present a system for privacy-preserving locally weighted linear regression, where the system not only protects the privacy of users but also encrypts the best-fit curve. Therefore, we use Paillier homomorphic encryption as the building modular to encrypt data and then apply the stochastic gradient descent in encrypted domain. After given a security analysis, we study how to let Paillier encryption deal with real numbers and implement the system in Python language with a couple of experiments on real-world data sets to evaluate the effectiveness, and show that it outperforms the state-of-the-art and occurs negligible errors compared with performing locally weighted linear regression in the clear.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoxia Dong",
                "org": "Department of Computer Science & Technology, East China Normal University,Shanghai,China"
            },
            {
                "name": "Jie Chen",
                "org": "Sch. of Software Eng., East China Normal Univ., Shanghai, China"
            },
            {
                "name": "Kai Zhang",
                "org": "School of Computer Science and Technology, Shanghai University of Electric Power, Shanghai, China#TAB#"
            },
            {
                "name": "Haifeng Qian",
                "org": "Sch. of Software Eng., East China Normal Univ., Shanghai, China"
            }
        ],
        "venue": "IEEE Access",
        "year": 2020
    },
    "J1wo3RAf": {
        "id": "J1wo3RAf",
        "title": "Characterizing user behaviors in location-based find-and-flirt services: Anonymity and demographics",
        "abstract": "WeChat, both a location-based social network (LBSN) and an online social network (OSN), is an immensely popular application in China. In this paper we specifically focus on a popular WeChat sub-service, namely, the  service, which is exemplary of a  service, similar to those on Momo and Tinder. Specifically, the  service reads in the current geographic location of the device to locate a list of other people using WeChat who are in the same vicinity. The user can then request to establish a WeChat friendship relation with any of the users on the list. In this paper, we explore: (i) if one gender tends to use the  service more than another; (ii) if users of  are more anonymous than ordinary WeChat users; (iii) if ordinary WeChat users are more anonymous than Twitter users. We also take an in-depth examination of the user anonymity and demographics in a combined fashion and examine: (iv) if ordinary WeChat females are more anonymous than ordinary males; (v) if  females are more anonymous than  males. By answering these questions, we will gain significant insights into modern online dating and friendship creation, insights that should be able to inform sociologists as well as designers of future  services.",
        "keywords": [
            "Location-based social networks",
            "Anonymity",
            "Demographics",
            "Find-and-flirt services"
        ],
        "authors": [
            {
                "name": "Minhui Xue",
                "org": "East China Normal University,Shanghai,ChinaNYU Shanghai,Shanghai,China"
            },
            {
                "name": "Limin Yang",
                "org": "East China Normal University,Shanghai,China"
            },
            {
                "name": "Keith W. Ross",
                "org": "NYU Shanghai,Shanghai,ChinaNew York University,New York,USA"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University,Shanghai,China"
            }
        ],
        "venue": "Peer-to-Peer Networking and Applications",
        "year": 2017
    },
    "Bnr3vAfS": {
        "id": "Bnr3vAfS",
        "title": "Data-Driven Privacy Analytics: A WeChat Case Study in Location-Based Social Networks.",
        "abstract": "Location-based Social Network (LBSN) services enable people to discover users nearby and establish the communication with them. WeChat as both LBSN and Online Social Network (OSN) application does not impose a real-name policy for usernames, leaving the users to choose how they want to be identified by nearby people. In this paper, we show the feasibility to stalk WeChat users in any city from any place in the world and in parallel examine the anonymity of those users. Based on previous studies, we develop an automated attacking methodology by using fake GPS location, smart phone emulation, task automation, and optical character recognition (OCR). We then study the prevalence and behavior of Anonymous and Identifiable WeChat users and correlate their anonymity with their behavior, especially for those who repeatedly query the People Nearby service, a feature that triggers WeChat to discover nearby people. By monitoring Wall Street for 7 days, we gather location information relevant to 3,215 distinct users and finally find that Anonymous users are largely less inhibited to be dynamic participants, as they query more and are more willing to move around in public. To the best of our knowledge, this is the first work that quantifies the relationship between user mobility and user anonymity. We expect our study to motivate better privacy design in WeChat.",
        "keywords": [],
        "authors": [
            {
                "name": "Rongrong Wang",
                "org": ""
            },
            {
                "name": "Minhui Xue",
                "org": ""
            },
            {
                "name": "Kelvin Liu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "WASA",
        "year": 2015
    },
    "cfPjWNFl": {
        "id": "cfPjWNFl",
        "title": "Symmetric Image Encryption Scheme Based on Chaotic System",
        "abstract": "This paper presents a new image encryption scheme based on composite chaotic system. An external key and two logistic systems are employed for encryption, which shuffle positions and substitute grey values of pixels of image. In the process of grey value substituting, it adopts sub key induced by external key to take samples. Through adding information of shuffle position matrix into the process of grey value substituting, processes of shuffle positions and substitute grey values are mixed in a simple and effective way, which improves coupling property of the encryption system.",
        "keywords": [
            "dynamic sample",
            "composite chaotic system",
            "Logistic maping",
            "image encryption"
        ],
        "authors": [
            {
                "name": "YAN Shi-yin",
                "org": "Department of Computer Science, East China Normal University, Shanghai "
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science, East China Normal University, Shanghai "
            },
            {
                "name": "LI Zhi-bin",
                "org": "Department of Computer Science, East China Normal University, Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2008
    },
    "uqyLExBa": {
        "id": "uqyLExBa",
        "title": "An absorptive capacity theory of knowledge spillover entrepreneurship",
        "abstract": "The knowledge spillover theory of entrepreneurship identifies new knowledge as a source of entrepreneurial opportunities, and suggests that entrepreneurs play an important role in commercializing new knowledge developed in large incumbent firms or research institutions. This paper argues that, knowledge spillover entrepreneurship depends not only on new knowledge but more importantly on entrepreneurial absorptive capacity that allows entrepreneurs to understand new knowledge, recognize its value, and commercialize it by creating a firm. This absorptive capacity theory of knowledge spillover entrepreneurship is tested using data based on U.S. metropolitan areas.",
        "keywords": [
            "entrepreneurship"
        ],
        "authors": [
            {
                "name": "haifeng qian",
                "org": "cleveland state university"
            },
            {
                "name": "zoltan j acs",
                "org": "george mason university"
            }
        ],
        "venue": "Small Business Economics",
        "year": 2013
    },
    "iPJgNf17": {
        "id": "iPJgNf17",
        "title": "Chosen-ciphertext attack secure public key encryption with auxiliary inputs",
        "abstract": "We consider public key encryption (PKE) schemes with auxiliary input, that is, the adversary is given any computationally uninvertible function of the secret key. Previous result only achieves security under chosen-plaintext attacks (CPA). In this paper, we construct public key encryption schemes that are secure under chosen-ciphertext attacks even when the adversary is given any computationally uninvertible function of the secret key as an auxiliary input. We follow the Naor–Yung ‘double encryption’ paradigm and generally transform any chosen-plaintext attack secure public key encryption into a chosen-ciphertext attack secure one in the auxiliary input model. Copyright © 2012 John Wiley & Sons, Ltd.",
        "keywords": [
            "auxiliary input",
            "secure public key encryption",
            "public key encryption scheme",
            "computationally uninvertible function",
            "secret key",
            "double encryption",
            "public key encryption",
            "chosen-ciphertext attack",
            "chosen-plaintext attack",
            "auxiliary input model"
        ],
        "authors": [
            {
                "name": "Zongyang Zhang",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai, 200240, China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai, 200240, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, No. 500 Dongchuan Road, Shanghai, 200241, China"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2012
    },
    "99hKDRMm": {
        "id": "99hKDRMm",
        "title": "Effects of validamycin on some enzymatic activities in soil.",
        "abstract": "There have been few investigations of the possible effects of validamycin on the enzymatic activities in soil. The objective of this present work was to study the short-term influence of enzymatic activity in validamycin treated soils. The results showed that high dose of validamycin introduced into soil had an significant effect on soil enzymatic activities, the degree of inhibition or promotion of enzymatic activities was not only related to the concentration of validamycin, but also to the remain time. Compared with the control (non treatment with validamycin), 240 ml.mg(-1) validamycin treatment caused a significant decrease (14%) of soil catalase activity; validamycin also inhibited urease activity to 67.3%, but subsequently, validamycin stimulated its activity higher than that of the control. Only the highest dose stimulated acid phophatase activities by 29.7%, and other concentration treatments had no effects on these enzymatic activities. The above results indicated that validamycin had effects on soil enzyme, but the effective time was short. It is also interesting to speculate that validamycin can be easily used by the soil microorganism as carbon source and energy.",
        "keywords": [
            "validamycin . catalase . urease . phophatase",
            "enzyme"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Baolan Hu",
                "org": "Ministry of Education Key Lab of Environment Remediation and Ecological Health, College of Environmental and Resource, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Zhiye Wang",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Xi Xu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Tao Hong",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            }
        ],
        "venue": "Environmental monitoring and assessment",
        "year": 2007
    },
    "BEX5ma1D": {
        "id": "BEX5ma1D",
        "title": "A New Construction of Time Capsule Signature.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Miaomiao Zhang",
                "org": ""
            },
            {
                "name": "Gongliang Chen",
                "org": ""
            },
            {
                "name": "Jianhua Li",
                "org": ""
            },
            {
                "name": "Licheng Wang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "IACR Cryptology ePrint Archive",
        "year": 2006
    },
    "REzTbs4z": {
        "id": "REzTbs4z",
        "title": "On the security of two password authenticated key agreement scheme using smart cards",
        "abstract": "",
        "keywords": [
            "authentication",
            "network security",
            "smart card",
            "anonymity"
        ],
        "authors": [
            {
                "name": "junzuo yang",
                "org": ""
            },
            {
                "name": "yongjian wang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "yuan zhou",
                "org": ""
            }
        ],
        "venue": "The Journal of China Universities of Posts and Telecommunications",
        "year": 2012
    },
    "Sfrd2z3K": {
        "id": "Sfrd2z3K",
        "title": "Preparation, statistical optimization and characterization of poly (3-hydroxybutyrate) fermented by Cupriavidus nector utilizing various hydrolysates of alligator weed (Alternanthera philoxeroides) as a sole carbon source.",
        "abstract": "Alligator weed (Alternanthera philoxeroides) is a stoloniferous, amphibious and perennial herb which has invaded many parts of the world and led to serious environmental and ecological problems. In order to exploit cheap carbon source for poly(3-hydroxybutyrate) (PHB) production, alligator weed hydrolysates were prepared by acid and enzyme treatment and used for PHB production via Cupriavidus necator. The bacterium utilized alligator weed enzymatic hydrolysate and produced the PHB concentration of 3.8 +/- 0.2 g/L at the conditions of pH 7.0, 27.5 degrees C, 1.5 g/L of nitrogen source, and 25 g/L of carbon source, this exceeded the value of 2.1 +/- 0.1 g/L from acid hydrolysate media at the same conditions. In order to obtain the optimum conditions of PHB production, response surface methodology was employed which improved PHB content. The optimum conditions for PHB production are as follows: carbon source, 34 g/L; nitrogen source, 2 g/L; pH, 7; temperature, 28 degrees C. After 72 hr of incubation, the bacterium produced 8.5 g/L of dry cell weight and 4.8 g/L of PHB. The PHB was subjected to Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), and Molecular weight analysis and found the melting temperature, number average molecular mass, and polydispersity were 168.20 degrees C, 185 kDa, and 2.1, respectively.",
        "keywords": [
            "alligator weed",
            "carbon source",
            "Cupriavidus necator",
            "enzymatic hydrolysate",
            "PHB"
        ],
        "authors": [
            {
                "name": "Youwei Zhang",
                "org": "Jiangsu Food & Pharmaceut Sci Coll, Sch Food Sci & Technol, 4 Meicheng Rd, Huaian 223003, Peoples R China"
            },
            {
                "name": "Tingting Li",
                "org": "Nanjing Forestry Univ, Dept Food Sci & Technol, Coll Light Ind & Food Engineer, Nanjing, Peoples R China"
            },
            {
                "name": "Yingbin Shen",
                "org": "Jinan Univ, Dept Food Sci & Engn, Guangzhou, Peoples R China"
            },
            {
                "name": "Li Wang",
                "org": "Jiangnan Univ, Sch Food Sci & Technol, Wuxi, Jiangsu, Peoples R China"
            },
            {
                "name": "Hui Zhang",
                "org": "Jiangnan Univ, Sch Food Sci & Technol, Wuxi, Jiangsu, Peoples R China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Jiangnan Univ, Sch Food Sci & Technol, Wuxi, Jiangsu, Peoples R China"
            },
            {
                "name": "Xiguang Qi",
                "org": "Jiangnan Univ, Sch Food Sci & Technol, Wuxi, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOTECHNOLOGY PROGRESS",
        "year": 2020
    },
    "SUel6QRe": {
        "id": "SUel6QRe",
        "title": "Bilinear-pairing based hybrid threshold signature scheme in Ad hoc network",
        "abstract": "In order to improve the signature and secret key security in Ad hoc network,this paper proposed a bilinear-pairing based hybrid threshold signature scheme which was based on bilinear-pairing and combined with hybrid threshold signature. The proposed scheme can not only improve the network transmission efficiency and save bandwidth,but also make the security and efficiency more suitable for the Ad hoc and sensor network.",
        "keywords": [
            "Ad hoc network",
            "threshold signature",
            "bilinear pairing",
            "network security",
            "sensor network",
            "threshold shared secret"
        ],
        "authors": [
            {
                "name": "HUANG Su-shan",
                "org": " Dept. of Computer Science & Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": " Dept. of Computer Science & Technology,East China Normal University,Shanghai ,China"
            }
        ],
        "venue": "Application Research of Computers",
        "year": 2010
    },
    "M6PNFkwJ": {
        "id": "M6PNFkwJ",
        "title": "Effect of nonylphenol on response of physiology and photosynthesis-related gene transcription of  ",
        "abstract": "Nonylphenol (NP) is regarded as a kind of persistent organic pollutant which exists ubiquitously in the environment. The objective of this study was to evaluate the effects of NP on  physiological indices and gene transcription. The results showed that NP stress inhibited algal growth in short-term bioassay. NP also decreased chlorophyll content, including chl a, chl b, and total chlorophyll. NP caused oxidant hurt by overproducing reactive oxygen species (ROS), which might destroy the overall membrane system to cause malondialdehyde content increase. NP inhibited photosynthesis-related gene transcription in  after 24 to 48 h exposure. The lowest transcript levels of B, A, and L in  decreased to only 18.5%, 7%, and 4% of the control, respectively. Taken together, our results demonstrate that NP is toxic to fresh algae growth by affecting the photosynthesis-related genes transcription and overproducing ROS to disrupt cell structure in a short period.",
        "keywords": [
            "Nonylphenol",
            "Chlorella vulgaris",
            "ROS",
            "Gene transcription"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of ChinaKey Laboratory of Non-point Sources Pollution Control,The Ministry of Agriculture of the People’s Republic of China,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Shutian Shi",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Shuqiong Yu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haiyan Jiang",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhifan Lin",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Environmental Monitoring and Assessment",
        "year": 2011
    },
    "S9bN1AMU": {
        "id": "S9bN1AMU",
        "title": "Robust password changing and DoS resilience for human-centric password authentication.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Jian Weng",
                "org": ""
            },
            {
                "name": "Ziping Wang",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2014
    },
    "ZgkPRE7T": {
        "id": "ZgkPRE7T",
        "title": "Establishment of genetic transformation system via <i>Agrobacterium</i> in tall fescue cultivar",
        "abstract": "Tall fescue (Festuca arundinacea Schreb.) is a cool-season turfgrass used on fairways in golf courses. The object of this study was to develop a more efficient,\n reliable, and repeatable approach in transforming the grass using Agrobacterium (EHA105), where β-glucuronidase gene (uidA) was used as a reporter and hygromycin phosphotransferase gene (hyg) as a selectable marker. An effective expression of transgene\n was observed in transforming 2-month-old calli derived from mature seeds (cv. Bingo) cultured on MS medium supplemented with\n 9 mg·L−1 2, 4-D. A two-step solid medium selection with increasing hygromycin concentration (from 30 to 50 mg·L−1) was used to obtain resistant calli. Transgenic plants have been produced from many independent transformed calli. The presence\n of functional β-glucuronidase gene (uidA) was detected in hygromycin-resistant calli. Transgenic plants were regenerated and PCR and Southern blot confirmed transgene\n integration in the tall fescue genome.",
        "keywords": [
            "β-glucuronidase gene uida clc number: q343 document code: a",
            "agrobacterium tumefaciens",
            "tall fescue",
            "transformation"
        ],
        "authors": [
            {
                "name": "Hai-feng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Shaukat Ali",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Liang Hong",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            },
            {
                "name": "Hao Xu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310014 China"
            }
        ],
        "venue": "Journal of Forestry Research",
        "year": 2006
    },
    "pd9Aa57C": {
        "id": "pd9Aa57C",
        "title": "Best Paper in the Front-End Design Category Session 10.5: \"The Synthesis of Cyclic Combinational Circuits",
        "abstract": "",
        "keywords": [
            "front end",
            "combinational circuit"
        ],
        "authors": [
            {
                "name": "Marc D. Riedel",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Sani R. Nassif",
                "org": ""
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": ""
            },
            {
                "name": "Peng Li",
                "org": ""
            },
            {
                "name": "Lawrence T. Pileggi",
                "org": ""
            },
            {
                "name": "Kubilay Atasu",
                "org": ""
            },
            {
                "name": "Laura Pozzi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2003
    },
    "g9IaHLJP": {
        "id": "g9IaHLJP",
        "title": "Formation of heat-induced cottonseed congossypin(7S) fibrils at pH 2.0.",
        "abstract": "Heat-induced protein aggregation is important for the texture of various food products. Many types of food proteins have been found to assemble into fibrillar structures under certain conditions. We studied fibril formation of cottonseed 7S storage protein upon heating (for 0-720 min) at 90°C and pH 2.0, investigated the conversion rate, and determined the extent of thermal aggregation.Thioflavin-T fluorescence and Congo-red analysis indicated the formation of amyloid-like fibrils upon heating. Centrifugal filtration indicated that the conversion was very low (<10%) until congossypin concentration up to 2 mg mL(-1), and the conversion increases with increasing heating time, but levels off after longer heating times. Dynamic light scattering and atomic force microscopy showed that the extent of thermal aggregation at pH 2.0, or contour length of the worm-like and fine-stranded aggregates, progressively increased with increasing heating time. Furthermore, reducing electrophoresis analyses indicated that progressive polypeptide hydrolysis occurred upon heating. Experiments indicate that congossypin can form heat-induced amyloid-like aggregates and the conversion of congossypin monomers into fibrils increased with heating time and protein concentration.The results would be of vital importance for the utilisation of cottonseed proteins to produce thermally induced fibrillar gels with excellent properties.",
        "keywords": [
            "amyloid fibrils",
            "assembly",
            "congossypin(7s)",
            "cottonseed protein",
            "heat-induced aggregation"
        ],
        "authors": [
            {
                "name": "Jian-Zhong Zhou",
                "org": "State Key Laboratory of Food Science and Technology and School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, People's Republic of China."
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Hai-Yan Yang",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            },
            {
                "name": "Hai-Feng Qian",
                "org": ""
            }
        ],
        "venue": "Journal of the science of food and agriculture",
        "year": 2014
    },
    "GKS9YcMG": {
        "id": "GKS9YcMG",
        "title": "Effects of streptomycin on growth of algae Chlorella vulgaris and Microcystis aeruginosa.",
        "abstract": "Streptomycin is a common contaminant in a variety of industrial and agricultural wastewaters. The available information on the potential toxicity of streptomycin of fresh algae implicated in the treatment of biological wastewater is extremely limited. The objective of this study was to evaluate the effects of streptomycin on physiological indices and photosynthesis-related gene transcription. The results of short-term batch bioassays indicated that streptomycin was more sensitive to cyanobacteria than to green algae. The EC50 of streptomycin in Microcystis aeruginosa and Chlorella vulgaris were 0.28 and 20.08 mg L(-1) , respectively. These selected streptomycin concentrations inhibited algal cell growth and decreased chlorophyll or phycocyanobilin content. Streptomycin also destroyed the overall membrane system, which was speculated from malondialdehyde (MDA) content and electrolyte leakage increasing after streptomycin exposure. Two algae were induced to increase their antioxidant enzyme activities to withstand streptomycin. However, the balance between oxidant substance and antioxidant enzyme was broken, because reactive oxygen species (ROS) content simultaneously increased. Streptomycin inhibited photosynthesis-related gene transcription in C. vulgaris and M. aeruginosa. Transcript levels of psaB, psbA, and rbcL in C. vulgaris decreased to only 14.5%, 32.2%, and 9.3% of the control, respectively. Similarly, the transcript levels of psaB, psbD, and rbcL in M. aeruginosa decreased markedly in the present of streptomycin. The transcription of these genes was 12.4%, 26.1%, and 28.4% of the control after 0.1 mg L(-1) streptomycin exposure, respectively. Our results demonstrate that streptomycin is toxic to fresh algae, affects photosynthesis-related gene transcription, and blocks electron transport and ROS overproduction.",
        "keywords": [
            "antioxidant enzyme",
            "chlorella vulgaris",
            "microcystis aeruginosa",
            "real-time pcr",
            "real time pcr"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Jingjing Li",
                "org": ""
            },
            {
                "name": "Xiangjie Pan",
                "org": ""
            },
            {
                "name": "Zhengqi Sun",
                "org": ""
            },
            {
                "name": "Chengbin Ye",
                "org": ""
            },
            {
                "name": "Gongqin Jin",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Environmental toxicology",
        "year": 2012
    },
    "8aAt0Fbj": {
        "id": "8aAt0Fbj",
        "title": "Influence of pH and ionic strength on heat-induced formation and rheological properties of cottonseed protein gels",
        "abstract": "",
        "keywords": [
            "ph",
            "rheology"
        ],
        "authors": [
            {
                "name": "jianzhong zhou",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "lei gao",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "Food and Bioproducts Processing",
        "year": 2015
    },
    "e8jQAYFg": {
        "id": "e8jQAYFg",
        "title": "Analysis of Enantioselective Biochemical, Physiological, and Transcriptional Effects of the Chiral Herbicide Diclofop Methyl on Rice Seedlings",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jun chen",
                "org": ""
            },
            {
                "name": "haiyan ding",
                "org": ""
            },
            {
                "name": "wei yong",
                "org": ""
            },
            {
                "name": "ruan songlin",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "ruiqin wang",
                "org": ""
            }
        ],
        "venue": "Journal of Agricultural and Food Chemistry",
        "year": 2012
    },
    "YzHB0jok": {
        "id": "YzHB0jok",
        "title": " Comparative molecular and metabolic responses of wheat seedlings (Triticum aestivum L.) to the imazethapyr enantiomers S-IM and R-IM.",
        "abstract": "The enantioselective effects of imazethapyr (IM) enantiomers on wheat seedlings in a hydroponic medium were studied. R-IM at 0.05mg/L exerted a stronger inhibitory effect on shoot weight and root weight than 0.05mg/L S-IM, suggesting that R-IM more severely inhibited growth. Oxidative damage, based on the anthocyanin content, malondialdehyde (MDA) content, antioxidant enzyme activities and transcript levels of antioxidant enzyme genes, were studied together with the cellular ultrastructure of wheat leaves. The anthocyanin and MDA contents in the R-IM treatment group were significantly increased compared with those in the control group, but no significant changes were observed in the S-IM treatment group. The antioxidant enzyme activities of CAT and SOD were inhibited by 0.32- and 0.73-fold, respectively, in the 14day R-IM treatment group compared to those in the control. However, the transcript levels of antioxidant enzyme genes, including CuZnSOD, POD and CAT, were downregulated in the 14day R-IM exposure group, but those of DHAR were not. The number and size of starch granules increased and chloroplast swelling was observed in wheat leaf cells after R-IM exposure, which showed that photosynthetic functions were potentially disturbed. These results directly or indirectly imply that R-IM exposure causes more oxidative stress and exerts a stronger negative effect on wheat than S-IM. A metabolomics approach revealed that the tricarboxylic acid cycle was heavily suppressed by R-IM treatment. Some amino acids (proline, threonine, lysine, valine) were increased by only the R-IM treatment, indicating the activation of antioxidant pathways. The decrease in a series of fatty acids implied that the cell membrane composition changed in response to R-IM. These results provide a deeper understanding of the enantioselective effects of IM enantiomers on the molecular and metabolic responses in wheat seedlings.",
        "keywords": [
            "Enantioselective",
            "Imazethapyr",
            "Metabolite profile",
            "Molecular responses",
            "Wheat"
        ],
        "authors": [
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China; Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2019
    },
    "141r3bUL": {
        "id": "141r3bUL",
        "title": "RETRACTED: Biologically active components and nutraceuticals in sesame and related products: a review and prospect",
        "abstract": "This article has been retracted at the request of the Editor-in-Chief. Please see Elsevier Policy on Article Withdrawal ( http://www.elsevier.com/locate/withdrawalpolicy ). Reason: It has been drawn to the Editors' attention that this paper contains significant parts copied (without citing the reference) from a previously published paper: Biologically Active Components and Nutraceuticals in Peanuts and Related Products: Review. Joel Isanga and Guo-Nong Zhang, Food Reviews International , 23 (2007) 123–140. As it duplicated previously published material, we must retract the paper published in Trends in Food Science & Technology .",
        "keywords": [
            "biological activity"
        ],
        "authors": [
            {
                "name": "Philip John Kanu",
                "org": "Milton Margai College of Education and Technology—Affiliated to the University of Sierra Leone, Goderich Campus, Freetown, Sierra Leone"
            },
            {
                "name": "Kerui Zhu",
                "org": "State Key Laboratory of School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, PR China"
            },
            {
                "name": "Jestina Baby Kanu",
                "org": "Milton Margai College of Education and Technology—Affiliated to the University of Sierra Leone, Goderich Campus, Freetown, Sierra Leone"
            },
            {
                "name": "Huiming Zhou",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, PR China"
            },
            {
                "name": "Kexue Zhu",
                "org": "State Key Laboratory of School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, PR China"
            }
        ],
        "venue": "Trends in Food Science & Technology",
        "year": 2007
    },
    "yieDhlCA": {
        "id": "yieDhlCA",
        "title": "Broadbeam design for massive MIMO systems with uniform rectangular array.",
        "abstract": "In massive MIMO systems, the control message needs to be broadcast to all users reliably in the cell using broadbeam with identical radiated power in all directions. In practice, rectangular array structure has been widely identified as a solution to deployment of massive MIMO systems. In this paper, we will show that there is no perfect broadbeam with rectangular array structure. Therefore, we develop a method for generating broadbeam that can allow tiny fluctuations in radiated power. Overall, this can serve as an ingredient for practical deployment of the massive MIMO systems.",
        "keywords": [],
        "authors": [
            {
                "name": "Deli Qiao",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Geoffrey Ye Li",
                "org": ""
            }
        ],
        "venue": "GlobalSIP",
        "year": 2015
    },
    "y9I3i0OJ": {
        "id": "y9I3i0OJ",
        "title": "Cryptanalysis of group signature scheme from ID-based signature scheme",
        "abstract": "In [1], C. Castelluccia presented the relationships between Identity-based (ID-based) signature schemes and group signature schemes. The methods of using Identity-based signature schemes to implement group signature schemes is also described. In [2], adopting such model, S. Popescu put forth an Identity-based group signature scheme. Such ideology is rather novel and creative. However, in this paper, we show that there are some security flaws in Castelluccia's model. We also present a security analysis of Popescu's scheme and demonstrate that the scheme is insecure either.",
        "keywords": [
            "id-based signature",
            "id-based signature scheme",
            "security flaw",
            "security analysis",
            "signature scheme",
            "identity-based group signature scheme",
            "group signature scheme",
            "s. popescu",
            "group signature",
            "identity-based signature scheme",
            "digital signature",
            "c. castelluccia"
        ],
        "authors": [
            {
                "name": "Haiyong Bao",
                "org": "Shanghai Jiao Tong University, Shanghai, P. R. China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong University, Shanghai, P. R. China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiao Tong University, Shanghai, P. R. China"
            }
        ],
        "venue": "InfoSecu '04 Proceedings of the 3rd international conference on Information security",
        "year": 2004
    },
    "vYc4Exnj": {
        "id": "vYc4Exnj",
        "title": "Validation of GOES-16 ABI infrared spatial response uniformity.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Dan Lindsey",
                "org": ""
            },
            {
                "name": "Chad Gravelle",
                "org": ""
            },
            {
                "name": "John Van Naarden",
                "org": ""
            },
            {
                "name": "Michael Ramirez",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Robert Iacovazzi",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            },
            {
                "name": "Vladimir Kondratovich",
                "org": ""
            },
            {
                "name": "Zhipeng Wang",
                "org": ""
            },
            {
                "name": "Mathew Gunshor",
                "org": ""
            },
            {
                "name": "Tim Schmit",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems XXIII",
        "year": 2018
    },
    "WLZwyQQ6": {
        "id": "WLZwyQQ6",
        "title": "Beyond Innovation: The Small Business Innovation Research Program as Entrepreneurship Policy",
        "abstract": "Entrepreneurship or new firm formation plays an increasingly important role in knowledge-based economic development. Public policy to encourage new firm formation has not focused on high quality, high potential firms, and the search for entrepreneurship policy with high economic impact is still needed. This research evaluates the efficacy of the US Small Business Innovation Research (SBIR) program from the perspective of promoting high technology entrepreneurship. In particular, we examine whether the local presence of SBIR awards is associated with increased new firm formation rates in the high technology sector. Although the primary objective of SBIR is to facilitate technological commercialization in small businesses, our policy analysis based on spatial multivariate methods suggests that this program may also serve as an effective entrepreneurship policy.",
        "keywords": [
            "entrepreneurship"
        ],
        "authors": [
            {
                "name": "haifeng qian",
                "org": "cleveland state university"
            },
            {
                "name": "kingsley e haynes",
                "org": "george mason university"
            }
        ],
        "venue": "Journal of Technology Transfer",
        "year": 2014
    },
    "qtBPtbXg": {
        "id": "qtBPtbXg",
        "title": "Effects of trilostane and fipronil on the reproductive axis in an early life stage of the Japanese medaka (Oryzias latipes).",
        "abstract": "Given the critical role of the hypothalamic-pituitary-gonadal (HPG) axis, it is conceivable that perturbations at any point along this axis can potentially affect reproduction in fish and other vertebrates. We investigated the effects of a 3β-hydroxysteroid dehydrogenase (3β-HSD) inhibitor, trilostane (TRI), and a gamma-aminobutyric acid (GABA)-receptor antagonist, fipronil (FIP), on the HPG axis using an early life stage of the Japanese medaka. The newly hatched larvae were exposed to TRI (100, 300 and 1000 μg/L) and FIP (3, 10 and 30 μg/L), respectively, until 28 days post-hatching. Exposure to TRI decreased the body length in males, whereas FIP inhibited growth in both sexes. The induction of steroidogenesis-regulating genes (including 3β-hsd) in males exposed to TRI, accompanied by increased vtg and er transcription, indicating a compensatory response to the presumed 3β-HSD inhibition. These compensatory responses were not observed in TRI-treated females. Regarding FIP exposure, the GABA blocker resulted in the down-regulation of fshr and lhr. A compensatory up-regulation of steroidogenesis-regulating genes partially explained the elevated transcripts of vtg genes in both males and females after FIP exposure. These results suggest that both the inhibition of 3β-HSD and the antagonism of GABA receptors are relevant modes of endocrine disruption that could impact the normal regulation of the HPG axis.",
        "keywords": [],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Rong Jin",
                "org": ""
            },
            {
                "name": "Zuhua Peng",
                "org": ""
            },
            {
                "name": "Qiwei Zhou",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Ecotoxicology (London, England)",
        "year": 2014
    },
    "QHikyOl3": {
        "id": "QHikyOl3",
        "title": "Cryptanalysis of Chang-Lin-Lam's ID-based Multisignature Scheme",
        "abstract": "Recently, Chang, Lin and Lam proposed an ID-based multisignature scheme without reblocking and predetermined signing order. Their scheme adopts users' id information as the public keys instead of random integers. They have claimed that it is computationally infeasible to derive the private key of Key Authentication Center (KAC) from the private keys of the authorized users, and the scheme has the property of resistance against collaboration attacks. However, we observed that their scheme cannot be applied in real world, for there are two defects in their scheme and the scheme doesn't satisfy with what they has claimed. The two drawbacks are: (1) not having an efficient verification algorithm (the signature almost cannot be verified for the exponent is too large). (2) Even if the signature can be verified, there would exist a forger within the same computation complexity of verification algorithm who can break the scheme (in other words, any one of the signing group can forge on any message for the whole signing group)",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Licheng Wang",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Sheng Guo",
                "org": "Shanghai Jiao Tong University, China"
            }
        ],
        "venue": "IMSCCS",
        "year": 2006
    },
    "vZbt8YlR": {
        "id": "vZbt8YlR",
        "title": "Formation of heat-induced cottonseed congossypin(7S) fibrils at pH 2.0: Formation of cottonseed congossypin fibrils",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jianzhong zhou",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "haiyan yang",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            }
        ],
        "venue": "Journal of the Science of Food and Agriculture",
        "year": 2014
    },
    "YQf0WCJI": {
        "id": "YQf0WCJI",
        "title": "Biological and chemical factors driving the temporal distribution of cyanobacteria and heterotrophic bacteria in a eutrophic lake (West Lake, China).",
        "abstract": "Physico-chemical parameters, hydrological conditions, and microbial interactions can affect the growth and persistence of cyanobacteria, but the interacting effects among these bloom-forming factors are still poorly known. This hampers our capacity to predict the occurrence of cyanobacterial bloom accurately. Here, we studied the relationship between temperature, N and P cycles, and the microbial community abundance and diversity at 0.5 m under the surface of West Lake (China) from January 21 to November 20, 2015, in order to better understand the key factors regulating temporal changes in the cyanobacterial community. Using high throughput sequencing of the 16S rRNA gene V3-V4 region, we studied the diversity and abundance of bacteria. In parallel, we measured physico-chemical parameters and followed the abundance of key genes involved in N fixation, denitrification, and nutrient uptake. Multivariate analyses suggest that P concentration and water temperature are the key factors controlling the outbreak of summer cyanobacterial bloom. RT-qPCR analyses of the bacterial community and measurements of the copy number of denitrification-related gene (nirK, nosZ, nirS) show that denitrification potential and denitrifying bacteria relative abundance (Pseudomonas and Bacillus) increased in concert with diazotrophic cyanobacterial genera (Anabaena, Nostoc, Aphanizomenon flos-aquae) and the common bloom-forming non-diazotrophic cyanobacterium genus Microcystis. The present study brings new insights on the complex interplay between physico-chemical parameters, heterotrophic bacterial community composition, nitrogen cycle, and cyanobacteria dominance in a eutrophic lake.",
        "keywords": [
            "Cyanobacterial toxins",
            "Denitrification",
            "Microbial community",
            "Microcystin",
            "Nitrogen cycle",
            "Phosphorus"
        ],
        "authors": [
            {
                "name": "Hao Song",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Guangfu Liu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China. hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Applied microbiology and biotechnology",
        "year": 2017
    },
    "x7Uy0qzc": {
        "id": "x7Uy0qzc",
        "title": "Security of Pon–Lu–Jeng’s Meta-He digital signature schemes",
        "abstract": "In 2001 He proposed a signature scheme that has the previously described advantages, notably: (1) It is based on two hard problems; (2) it uses the same modulus; and (3) it only requires one pair of public and private keys. Soon, Pon et al. generalized He’s scheme in order to get efficient digital signature schemes with high security (their schemes are claimed to be based on two cryptographic assumptions simultaneously). In this paper, we shall point out that He and Pon et al.’s signature schemes are not based on two cryptographic assumptions simultaneously. So all their signature schemes in fact have not any efficiency advantage if only based on one cryptographic assumptions. Meanwhile, the task of designing efficient digital signature schemes based on two cryptographic assumptions simultaneously is still an open problem.",
        "keywords": [
            "cryptanalysis",
            "factoring",
            "discrete logarithms",
            "digital signature",
            "cryptography",
            "discrete logarithm"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People’s Republic of China"
            },
            {
                "name": "Zhenfu Cao",
                "org": ""
            },
            {
                "name": "Haiyong Bao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, People’s Republic of China"
            }
        ],
        "venue": "Applied Mathematics and Computation",
        "year": 2005
    },
    "qhWugOTY": {
        "id": "qhWugOTY",
        "title": "Effect of the frying process on the properties of gluten protein of you-tiao.",
        "abstract": "Wheat is one of the most important grains in cereal products. Gluten protein is an important component of wheat and plays an important role in the human diet. The variations of gluten protein in you-tiao were investigated in this study during frying, with a view toward a theoretical basis for the improvement of processing methods and quality in you-tiao. During the processing of you-tiao, gluten protein altered significantly. Analysis of secondary structure and surface hydrophobicity indicated that gluten protein molecules were unfolded and decomposed after frying, providing the opportunity for protein reaggregation. The extractability and sodium dodecyl sulphate-polyacrylamide gel electrophoresis profiles demonstrated the decomposition and reaggregation of gluten protein. Analysis of the chemical interactions proved that gluten protein molecules aggregated mainly by disulfide bonds and hydrophobic interactions. Frying induced a loose and uneven gluten network.",
        "keywords": [
            "Chemical interactions",
            "Conformation",
            "Cross-linking",
            "Frying",
            "Gluten protein",
            "Unfolding"
        ],
        "authors": [
            {
                "name": "Ruoxin Zhou",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Juan Sun",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "HgSHjpp1": {
        "id": "HgSHjpp1",
        "title": "Effects of glufosinate on antioxidant enzymes, subcellular structure, and gene expression in the unicellular green alga Chlorella vulgaris.",
        "abstract": "Greater exposure to herbicide increases the likelihood of harmful effects in humans and the environment. Glufosinate, a non-selective herbicide, inhibits glutamine synthetase (GS) and thus blocks ammonium assimilation in plants. In the present study, the aquatic unicellular alga Chlorella vulgaris was chosen to assess the effects of acute glufosinate toxicity. We observed physiological changes during 12-96 h of exposure, and gene transcription during 6-48 h of exposure. Exposure to glufosinate increased malondialdehyde content by up to 2.73 times compared with the control, suggesting that there was some oxidative damage. Electron microscopy also showed that there were some chloroplast abnormalities in response to glufosinate. The activities of the antioxidant enzymes superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) also increased markedly in the presence of glufosinate. Maximum activities of SOD, POD, and CAT were 2.90, 2.91, and 2.48 times that of the control, respectively. These elevated activities may help alleviate oxidative damage. A real-time polymerase chain reaction (PCR) assay showed changes in transcript abundances of three photosynthetic genes, psaB, psbC, and rbcL. The results showed that glufosinate reduced the transcript abundances of the three genes after 12h exposure. The lowest abundances of psaB, psbC and rbcL transcripts in response to glufosinate exposure were 38%, 16% and 43% of those of the control, respectively. Our results demonstrate that glufosinate affects the activities of antioxidant enzymes, disrupts chloroplast ultrastructure, and reduces transcription of photosynthesis-related genes in C. vulgaris.",
        "keywords": [
            "enzyme",
            "real time polymerase chain reaction",
            "gene transcription",
            "enzyme assay",
            "gene expression",
            "electron microscopy",
            "real time pcr",
            "peroxidase"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Wei Chen",
                "org": ""
            },
            {
                "name": "G Daniel Sheng",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People's Republic of China"
            },
            {
                "name": "Xiaoyan Xu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People's Republic of China"
            },
            {
                "name": "Weiping Liu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, People's Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Aquatic toxicology (Amsterdam, Netherlands)",
        "year": 2008
    },
    "dixnqxFG": {
        "id": "dixnqxFG",
        "title": "Online /offline multi-signature scheme in standard model",
        "abstract": "Online/offline multi-signature schemes allowed multiple users to efficiently sign on a common message and then generated a single signature. This paper convinced the verifiers that who had signed on the message. Computed most computations before the message was given. Only small quantities of computations were needed after the message was available. Gave the formal definition of the online/offline multi-signature and the security notion. Based on the online/offline signature proposed by Guo,with the method that used by Lu et al to construct multi-signature,gave a concrete scheme. It could be proven secure in the standard model,and it was efficient.",
        "keywords": [
            "online/offline signature",
            "key model",
            "signatures",
            "standard model",
            "multi-signature"
        ],
        "authors": [
            {
                "name": "LU Chao",
                "org": " Dept. of Computer Science,School of Information Science & Technology,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": " Dept. of Computer Science,School of Information Science & Technology,East China Normal University,Shanghai ,China"
            }
        ],
        "venue": "Application Research of Computers",
        "year": 2010
    },
    "Eg1kBrJU": {
        "id": "Eg1kBrJU",
        "title": "Inhibitory effects of paraquat on photosynthesis and the response to oxidative stress in Chlorella vulgaris.",
        "abstract": "This study investigated the effects of paraquat, a widely used herbicide, on the aquatic unicellular alga Chlorella vulgaris through short-term toxicity tests at the physiological and gene transcriptional levels. Exposure to 0.5 μM paraquat increased\n the activities of the antioxidant enzymes superoxide dismutase, peroxidase, and catalase to levels 4.93, 3.19, and 3.09 times\n higher, respectively, than those of the control. Furthermore, exposure to 0.75 μM paraquat increased the activities of these\n antioxidant enzymes to even higher levels. The decrease in chlorophyll content and the increases in reactive oxygen species\n (ROS) and malondialdehyde content following exposure to paraquat suggest that the alga was severely damaged and cell growth\n was greatly inhibited. Real-time PCR showed that paraquat reduced the transcript abundance of psaB and rbcL to 7.09 and 29.83% of the control, respectively. Our results demonstrate that paraquat inhibited electron transport and\n CO2 assimilation, and also triggered the synthesis of ROS that disrupt cellular structure and inhibit cell growth.",
        "keywords": [
            "chlorella vulgaris",
            "gene transcript",
            "paraquat",
            "real-time pcr",
            "electron transport",
            "real time pcr",
            "cell growth",
            "peroxidase",
            "toxicity testing",
            "real time",
            "gene transcription",
            "oxidation",
            "electron transfer",
            "photosynthesis",
            "enzymes",
            "toxicity",
            "oxygen",
            "enzyme activity",
            "carbon dioxide",
            "transcription"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Wei Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Liwei Sun",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Yuanxiang Jin",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Weiping Liu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Ecotoxicology (London, England)",
        "year": 2009
    },
    "K0zfANoQ": {
        "id": "K0zfANoQ",
        "title": "Contrasting silver nanoparticle toxicity and detoxification strategies in Microcystis aeruginosa and Chlorella vulgaris: New insights from proteomic and physiological analyses.",
        "abstract": "Several studies have shown that AgNPs can be toxic to phytoplankton, but the underlying cellular mechanisms still remain largely unknown. Here we studied the toxicity and detoxification of AgNPs (and ionic silver released by the AgNPs) in a prokaryotic (Microcystis aeruginosa) and a eukaryotic (Chlorella vulgaris) freshwater phytoplankton species using a combination of proteomic, gene transcription, and physiological analyses. We show that AgNPs were more toxic to the growth, photosynthesis, antioxidant systems, and carbohydrate metabolism of M. aeruginosa than of C. vulgaris. C. vulgaris could detoxify efficiently AgNPs-induced ROS species via induction of antioxidant enzymes (superoxide dismutase or SOD, peroxidase or POD, catalase or CAT, and glutamine synthetase), allowing photosynthesis to continue unabated at growth-inhibitory AgNPs concentration. By contrast, the transcription and expression of SOD and POD in M. aeruginosa was inhibited by the same AgNPs exposure. The present study shed new lights on the AgNPs toxicity mechanisms and detoxification strategies in two freshwater algae of contrasting AgNPs sensitivity.",
        "keywords": [
            "Antioxidant",
            "Chlorella vulgaris",
            "DIGE",
            "Microcystis aeruginosa",
            "Silver nanoparticles",
            "Silver toxicity"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Kun Zhu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haiping Lu",
                "org": "College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "Si Chen",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhongjing Zhou",
                "org": "State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, PR China."
            },
            {
                "name": "Zhiping Deng",
                "org": "State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, PR China."
            },
            {
                "name": "Jun Chen",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: azwfu@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2016
    },
    "U0ZVTHq1": {
        "id": "U0ZVTHq1",
        "title": "Effect of nonylphenol on response of physiology and photosynthesis-related gene transcription of Chlorella vulgaris.",
        "abstract": "Nonylphenol (NP) is regarded as a kind of persistent organic pollutant which exists ubiquitously in the environment. The objective\n of this study was to evaluate the effects of NP on Chlorella vulgaris physiological indices and gene transcription. The results showed that NP stress inhibited algal growth in short-term bioassay.\n NP also decreased chlorophyll content, including chl a, chl b, and total chlorophyll. NP caused oxidant hurt by overproducing\n reactive oxygen species (ROS), which might destroy the overall membrane system to cause malondialdehyde content increase.\n NP inhibited photosynthesis-related gene transcription in C. vulgaris after 24 to 48 h exposure. The lowest transcript levels of psaB, psbA, and rbcL in C. vulgaris decreased to only 18.5%, 7%, and 4% of the control, respectively. Taken together, our results demonstrate that NP is toxic\n to fresh algae growth by affecting the photosynthesis-related genes transcription and overproducing ROS to disrupt cell structure\n in a short period.",
        "keywords": [
            "chlorella vulgaris",
            "gene transcription",
            "nonylphenol",
            "ros"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xiangjie Pan",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Shutian Shi",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Shuqiong Yu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Haiyan Jiang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhifan Lin",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Environmental monitoring and assessment",
        "year": 2011
    },
    "AHzqefPK": {
        "id": "AHzqefPK",
        "title": "Direct current circuit analysis based clock network design",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "charles j alpert",
                "org": ""
            },
            {
                "name": "joseph n kozhaya",
                "org": ""
            },
            {
                "name": "zhuo li",
                "org": ""
            },
            {
                "name": "joseph j palumbo",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "phillip j restle",
                "org": ""
            },
            {
                "name": "chin ngai sze",
                "org": ""
            },
            {
                "name": "ying zhou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "p8V7COtN": {
        "id": "p8V7COtN",
        "title": "China’s Development Disconnect",
        "abstract": "",
        "keywords": [
            "economic model",
            "knowledge based economy",
            "structural equation model",
            "data collection",
            "economics"
        ],
        "authors": [
            {
                "name": "richard florida",
                "org": "rotman school of management"
            },
            {
                "name": "charlotta mellander",
                "org": "jonkoping international business school"
            },
            {
                "name": "haifeng qian",
                "org": "cleveland state university"
            }
        ],
        "venue": "Environment and Planning A",
        "year": 2012
    },
    "5nIe4jyf": {
        "id": "5nIe4jyf",
        "title": "Stochastic Preconditioning for Iterative Linear Equation Solvers",
        "abstract": "This paper presents a new stochastic preconditioning approach. For symmetric\ndiagonally-dominant M-matrices, we prove that an incomplete LDL factorization\ncan be obtained from random walks, and used as a preconditioner for an\niterative solver, e.g., conjugate gradient. It is argued that our factor\nmatrices have better quality, i.e., better accuracy-size tradeoffs, than\npreconditioners produced by existing incomplete factorization methods.\nTherefore the resulting preconditioned conjugate gradient (PCG) method requires\nless computation than traditional PCG methods to solve a set of linear\nequations with the same error tolerance, and the advantage increases for larger\nand denser sets of linear equations. These claims are verified by numerical\ntests, and we provide techniques that can potentially extend the theory to more\ngeneral types of matrices.",
        "keywords": [
            "random walk",
            "numerical analysis",
            "conjugate gradient",
            "linear equations"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "9d8PNS1E": {
        "id": "9d8PNS1E",
        "title": "POSTER: Arranging the Layout of Alphanumeric Buttons--the Role of Passwords",
        "abstract": "A typical but trivial layout of alphanumeric buttons in the touchscreen setting is to arrange the 10 digits and 26 letters in a natural order. This arrangement does not take into account the frequencies of letters and digits when the users touch the buttons to key in their passwords or messages. We examine large scale datasets of over 141 million passwords collected from several leading websites for social networking, Internet forums, gaming, dating, and various other online service providers in China, and find that the distribution of letters in passwords is quite close to that in Chinese language. Based on the letter/digit frequencies, we further propose an alphanumeric button layout scheme with the following advantages: the buttons are clicked as uniformly as possible, so that the lifetime of the touchscreen can be prolonged and finger oil residues may scatter more evenly over the button area of the screen; and in the meantime, the movements of users' fingers are improved to enhance good user experience when inputting messages. The idea behind the layout is potentially applicable to diversified races.",
        "keywords": [
            "touchscreen",
            "miscellaneous",
            "user interfaces",
            "alphanumeric button",
            "passwords"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Qiang Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            },
            {
                "name": "Jian Weng",
                "org": ""
            }
        ],
        "venue": "ACM Conference on Computer and Communications Security",
        "year": 2014
    },
    "PKFT6ztJ": {
        "id": "PKFT6ztJ",
        "title": "Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity.",
        "abstract": "With the gradual ban on brominated flame retardants (FRs), the application of organophosphate flame retardants (OPFRs) has increased remarkably. Considering the structural similarity between OPFRs and organophosphate pesticides, hypotheses that OPFRs may interfere with neurodevelopment as organophosphate pesticides are reasonable. In this study, the neurotoxicity of three OPFRs, including tri-n-butyl phosphate (TNBP), tris (2-butoxyethyl) phosphate (TBOEP) and tris (2-chloroethyl) phosphate (TCEP), was evaluated in zebrafish larvae and then compared with the neurotoxicity of organophosphate pesticide chlorpyrifos (CPF). The results showed that similar to CPF, exposure to OPFRs for 5days resulted in significant changes in locomotor behavior, either in free swimming or in photomotor response. However, given the transcriptional changes that occur in nervous system genes in response to OPFRs and CPF, as well as the altered enzyme activity of AChE and its mRNA level, the underlying mechanisms for neurotoxicity among these organophosphate chemicals might be varied. In summary, the results confirm the potential neurodevelopmental toxicity of OPFRs and underscore the importance of identifying the mechanistic targets of the OPFRs with specific moieties. Furthermore, as the neurobehavioral responses are well conserved among vertebrates and the exposure of children to OPFRs is significant, a thorough assessment of the risk of OPFRs exposure during early development should be highly emphasized in future studies. ",
        "keywords": [
            "Acetylcholinesterase (AChE) activity",
            "Aquatic organism",
            "Early life stage",
            "Gene transcriptional analysis",
            "Locomotor behavior",
            "Nervous system"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Wenbin Xu",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Peng",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haigang Chen",
                "org": "South China Sea Fisheries Research Institute, Chinese Academy of Fishery Science, No. 231 Xingangxi Road, Guangzhou 510300, PR China."
            },
            {
                "name": "Lin Ren",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hana Tan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Dan Xiao",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: azwfu@zjut.du.cn."
            }
        ],
        "venue": "Neurotoxicology and teratology",
        "year": 0
    },
    "gFK1bUNj": {
        "id": "gFK1bUNj",
        "title": "Reduction of 5-hydroxymethylfurfural formation by flavan-3-ols in Maillard reaction models and fried potato chips.",
        "abstract": "The present study demonstrates that flavan-3-ols could be effective addtives for reducing HMF levels in fried potato chips without changing sensory properties.",
        "keywords": [
            "5-hydroxymethylfurfural (HMF)",
            "Maillard reaction",
            "characterization",
            "flavan-3-ols",
            "fried potato chips",
            "proanthocyanidins"
        ],
        "authors": [
            {
                "name": "Yajing Qi",
                "org": "Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, 100048, China."
            },
            {
                "name": "Hao Zhang",
                "org": "School of Food Science and Technology, Jiangnan University, Wuxi, 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, 100048, China."
            },
            {
                "name": "Hui Zhang",
                "org": "Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University, Beijing, 100048, China."
            },
            {
                "name": "Li Wang",
                "org": "School of Food Science and Technology, Jiangnan University, Wuxi, 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology, Jiangnan University, Wuxi, 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "School of Food Science and Technology, Jiangnan University, Wuxi, 214122, China."
            }
        ],
        "venue": "Journal of the science of food and agriculture",
        "year": 2018
    },
    "yP2XNvBR": {
        "id": "yP2XNvBR",
        "title": "Interaction between Vaccinium bracteatum Thunb. leaf pigment and rice proteins.",
        "abstract": "In this study, we investigated the interaction of Vaccinium bracteatum Thunb. leaf (VBTL) pigment and rice proteins. In the presence of rice protein, VBTL pigment antioxidant activity and free polyphenol content decreased by 67.19% and 68.11%, respectively, and L(∗) of the protein-pigment complex decreased significantly over time. L(∗) values of albumin, globulin and glutelin during 60-min pigment exposure decreased by 55.00, 57.14, and 54.30%, respectively, indicating that these proteins had bound to the pigment. A significant difference in protein surface hydrophobicity was observed between rice proteins and pigment-protein complexes, indicating that hydrophobic interaction is a major binding mechanism between VBTL pigment and rice proteins. A significant difference in secondary structures between proteins and protein-pigment complexes was also uncovered, indicating that hydrogen bonding may be another mode of interaction between VBTL pigment and rice proteins. Our results indicate that VBTL pigment can stain rice proteins with hydrophobic and hydrogen interactions.",
        "keywords": [
            "Hydrogen bonding",
            "Hydrophobic interaction",
            "Rice protein",
            "Secondary structure",
            "Surface hydrophobicity",
            "Vaccinium bracteatum Thunb."
        ],
        "authors": [
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Yuan Xu",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Sumei Zhou",
                "org": "Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, Beijing 100193, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Meihua Fan",
                "org": "Jiangsu Institute of Poultry Sciences, Yangzhou 225125, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2016
    },
    "cDmsBDse": {
        "id": "cDmsBDse",
        "title": "Anti-diabetic activity of cassava cross-linked octenyl succinic maltodextrin in STZ-induced diabetic mice.",
        "abstract": "The effect of cassava cross-linked octenyl succinic maltodextrin (CCOMD) on diabetic mice was investigated in this study. For CCOMD-L (low dose) and CCOMD-H (high dose) groups, the body weights were recovered by 14.9% and 18.5%, respectively, which were significantly higher than that of model control group. It was also found that the blood glucose and insulin levels were ameliorated in the diabetic mice by the CCOMD diet. Moreover, the CCOMD diet decreased the plasma total cholesterol level (8.1-9.1%) and LDL cholesterol level (28.9-39.4%), and improved the plasma HDL cholesterol level (13.8-15.3%) and intestine short chain fatty acid content. The results indicated that CCOMD administration may be helpful for treating and preventing hyperlipidemia and hyperglycemia in diabetes.",
        "keywords": [
            "blood glucose",
            "cassava cross-linked octenyl succinic maltodextrin",
            "diabetic mice"
        ],
        "authors": [
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu, China."
            },
            {
                "name": "Maoqiang Zheng",
                "org": "Wuxi Cofco Engineering &amp; Technology Co., Ltd., Wuxi 214036, Jiangsu, China."
            },
            {
                "name": "Yingyao Wang",
                "org": "Academy of State Administration of Grain, Beijing 100037, China."
            },
            {
                "name": "Ying Zhang",
                "org": "China National Research Institute of Food &amp; Fermentation Industries, Beijing 100027, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu, China."
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2014
    },
    "vDIeaBB3": {
        "id": "vDIeaBB3",
        "title": "Efficient public key encryption with smallest ciphertext expansion from factoring",
        "abstract": "For public key encryption schemes, adaptive chosen ciphertext security is a widely accepted security notion since it captures a wide range of attacks. SAEP and SAEP+ are asymmetric encryption schemes which were proven to achieve semantic security against adaptive chosen ciphertext attacks. However, the bandwidth for message is essentially worse, that is the ciphertext expansion (the length difference between the ciphertext and the plaintext) is too large. In most of the mobile networks and bandwidth constrained communication systems, it is necessary to securely send as many messages as possible. In this article, we propose two chosen-ciphertext secure asymmetric encryption schemes. The first scheme is a generic asymmetric encryption padding scheme based on trapdoor permutations. The second one is its application to the Rabin-Williams function which has a very fast encryption algorithm. These asymmetric encryption schemes both achieve the optimal bandwidth w.r.t. the ciphertext expansion, namely with the smallest ciphertext expansion. Further, tight security reductions are shown to prove the security of these encryption schemes.",
        "keywords": [
            "Encryption scheme",
            "Tight security",
            "Factoring",
            "Random oracle model",
            "SAEP",
            "Random permutation model",
            "94A60"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Computer Science and Technology Department, East China Normal University, Shanghai, China 200062"
            },
            {
                "name": "Yuan Zhou",
                "org": "National Computer Network Emergency Response Technical Team (Coordination Center of China), Beijing, China"
            },
            {
                "name": "Zhibin Li",
                "org": "Computer Science and Technology Department, East China Normal University, Shanghai, China 200062 and Institute of Theoretical Computing, East China Normal University, Shanghai, China 200062"
            },
            {
                "name": "Zecheng Wang",
                "org": "Computer Science and Technology Department, East China Normal University, Shanghai, China 200062"
            },
            {
                "name": "Bing Zhang",
                "org": "National Computer Network Emergency Response Technical Team (Coordination Center of China), Beijing, China"
            }
        ],
        "venue": "Des. Codes Cryptography",
        "year": 2008
    },
    "aQjtr2cB": {
        "id": "aQjtr2cB",
        "title": "Cryptanalysis and Improvement of a Block Cipher Based on Multiple Chaotic Systems",
        "abstract": "",
        "keywords": [
            "block cipher"
        ],
        "authors": [
            {
                "name": "Jun He",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            },
            {
                "name": "Zhibin Li",
                "org": ""
            }
        ],
        "venue": "Mathematical Problems in Engineering",
        "year": 2010
    },
    "SXMwqUGJ": {
        "id": "SXMwqUGJ",
        "title": "POSTER: Using Chinese Characters for Authentication--Algorithmic Framework and Empirical Results",
        "abstract": "Graphical password methods rely on human experience and hand selection (not well-quantified metric) to evaluate the appropriateness and the confusion of the challenge images. In this paper we propose to use for authentication Chinese characters, for which the entropy can be up to 9.65 (much larger than other languages). We first show an algorithmic framework to authenticate a user and then present an empirical analysis conducted at a university. The advantages of the framework include the following: the storage overhead is low; no personal experience or hand selection is involved; there is no predefined dictionary of likely choices; and it can be easily referenced by personal-style cues. Our study shows that the number of participants that prefer our framework is much close to that in favor of graphical passwords, with an interesting outcome that the two groups of participants present significantly distinct backgrounds. Our framework and graphical passwords can be used as candidate authentication methods for users with different backgrounds. We also measure user choices of patterns and find that there is a slight preference of the 3$\\\\times$3 grid to the circle patterns. While the proposed framework prescribes the challenge characters, the users have the option to define challenge characters of their own.",
        "keywords": [
            "security and protection",
            "user/machine systems",
            "human factors in security",
            "entropy",
            "evaluation"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Yu Yu",
                "org": ""
            },
            {
                "name": "Qiang Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            },
            {
                "name": "Jian Weng",
                "org": ""
            }
        ],
        "venue": "ACM Conference on Computer and Communications Security",
        "year": 2014
    },
    "jJGo50aM": {
        "id": "jJGo50aM",
        "title": "Feedback regulation between aquatic microorganisms and the bloom-forming cyanobacterium Microcystis aeruginosa",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China"
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China"
            },
            {
                "name": "Hans W Paerl",
                "org": "Institute of Marine Sciences, University of North Carolina at Chapel Hill, Morehead City, NC, 28557, USA"
            },
            {
                "name": "Yiling Chen",
                "org": "Department of Civil, Environmental, and Geo- Engineering, University of Minnesota, Minneapolis, MN, 55455-0116, USA"
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China"
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China"
            }
        ],
        "venue": "Applied and Environmental Microbiology",
        "year": 2019
    },
    "edwxWZvy": {
        "id": "edwxWZvy",
        "title": "Multi-receiver identity-based proxy signcryption",
        "abstract": "Based on the identity-based signcryption, this paper proposed a multi-receiver identity-based proxy signcryption scheme, in which some good characteristics of bilinear pairing are used. The new scheme offers a good solution to the problem of signature with a lot of multi-receiver. Additionally, this scheme which can achieve confidentiality, public verification and high security, was simply designed and easily implemented. Only one pairing computation is needed in it to signcrypt a single message for all receivers. As a result, the efficiency gain of the new scheme is huge especially when there are a large number of recipients.",
        "keywords": [
            "identity-based signcryption",
            "proxy signcryption",
            "signcryption",
            "multi-receiver"
        ],
        "authors": [
            {
                "name": "HU Zhen-peng",
                "org": "Department of Computer Science , East China Normal University , Shanghai , China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science , East China Normal University , Shanghai , China"
            },
            {
                "name": "LI Zhi-bin",
                "org": "Department of Computer Science , East China Normal University , Shanghai , China"
            }
        ],
        "venue": "Journal of East China Normal University(Natural Science)",
        "year": 2008
    },
    "aVOvCR6a": {
        "id": "aVOvCR6a",
        "title": "Leaf proteome analysis provides insights into the molecular mechanisms of bentazon detoxification in rice.",
        "abstract": "Bentazon is a widely used herbicide that selectively removes broad-leaf weeds by competing with plastoquinone for the binding site in the D1 protein and interrupting the PET (photosynthetic electron transfer) chain. However, monocotyledonous plants, such as rice, show strong resistance to bentazon due to CYP81A6 induction, which results in herbicide detoxification. Here, we confirmed that rice was sensitive to bentazon treatment during the initial exposure period, in which bentazon rapidly inhibited photosynthesis efficiency and electron transfer, based on results of chlorophyll fluorescence analysis. In order to gain a comprehensive, pathway-oriented, mechanistic understanding of the effects directly induced by bentazon, we employed 2D-DIGE (two-dimensional difference gel electrophoresis) to analyze the leaf proteome after 8h of bentazon treatment coupled with individual protein identification by MALDI-TOF (Matrix assisted laser desorption/ionization-time of flight) MS/MS. Proteomic analyses revealed that bentazon induced the relative upregulation or downregulation of 30 and 71 proteins (by 1.5-fold or more, p<0.05), respectively. The pathways involved include photosynthesis processes, carbohydrate metabolism, antioxidant systems, and DNA stabilization and protein folding. Protein analysis data revealed that bentazon primarily suppressed photosynthesis processes, and showed inhibitory effects on carbohydrate metabolism and ATP synthesis, whereas several stress response proteins were induced in response to bentazon. Importantly, we identified a 519kD protein containing two histidine kinase-like ATPase domains and a C3HC4 RING type zinc finger domain which may function as a transcript factor to drive expression of detoxification genes such as CYP81A6, leading to bentazon tolerance. This study identifies, for the first time, a candidate transcription factor that could up-regulate CYP81A6 expression, and provides a foundation for further research to advance our knowledge of mechanisms of bentazon resistance in rice.",
        "keywords": [
            "Bentazon",
            "Chlorophyll fluorescence",
            "DIGE",
            "Gene transcription",
            "Proteomics"
        ],
        "authors": [
            {
                "name": "Yingzhi Fang",
                "org": "Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Haiping Lu",
                "org": "College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Si Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Kun Zhu",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hao Song",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China."
            }
        ],
        "venue": "Pesticide biochemistry and physiology",
        "year": 2015
    },
    "ChZLDT8h": {
        "id": "ChZLDT8h",
        "title": "Constructing practical signcryption KEM from standard assumptions without random oracles",
        "abstract": "We present a direct construction for signcryption Key Encapsulation Mechanism (KEM) without random oracles under standard complexity assumptions. Chosen-ciphertext security is proven in the standard model under the DBDH assumption, and unforgeability is proven in the standard model under the CDH assumption. The proof technique allows us to achieve strong unforgeability from the weakly unforgeable Waters signature. The validity of the ciphertext of our signcryption KEM can be verified publicly, without knowledge of the decryption key.",
        "keywords": [
            "practical signcryption kem",
            "standard complexity assumption",
            "dbdh assumption",
            "decryption key",
            "cdh assumption",
            "standard assumption",
            "chosen-ciphertext security",
            "strong unforgeability",
            "waters signature",
            "random oracle",
            "signcryption kem",
            "signcryption key encapsulation mechanism",
            "standard model",
            "signcryption"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": "Department of Computer Science and Technology, East China Normal University, China,State Key Laboratory of Integrated Services Networks, Xidian University, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Yu Yu",
                "org": "Institute for Interdisciplinary Information Sciences, Tsinghua University, China"
            },
            {
                "name": "Yuan Zhou",
                "org": "Network Emergency Response Technical Team, Coordination Center, China"
            },
            {
                "name": "Jian Weng",
                "org": "Department of Computer Science, Jinan University, China"
            }
        ],
        "venue": "ACNS",
        "year": 2013
    },
    "9X7iIVRR": {
        "id": "9X7iIVRR",
        "title": "Provably secure RSA-type signature based on conic curve",
        "abstract": "In electronic communication and wireless communication, message authentication should be necessary. However, traditional method message authentication code (MAC) employs a symmetric cryptographical technique and it needs to keep a shared private key between two parties. For convenience, people now begins to use public key techniques to provide message authentication. In wireless communication, we shall save more space for message itself because of the limited resources. Therefore, we believe that our proposed digital signature scheme will be more fitful for this kind of communication due to the following merits: (1) in addition to inheriting the merits of RSA signature such as high verification efficiency, the proposed scheme also shows its advantage over RSA by resisting low public key exponent attack; (2) comparing with 1024 bits RSA, our digital signature scheme can sign 2048-bit long message once, and generate a signature with 1025 bits length which doubles the capacity of the 1024-bit RSA signature; (3) the scheme is provably secure and its security is tightly related to the hardness of conic-based (CB)-RSA assumption. Copyright © 2008 John Wiley & Sons, Ltd.",
        "keywords": [
            "provable security",
            "conic curve",
            "mobile communication"
        ],
        "authors": [
            {
                "name": "Xiaolei Dong",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, P.R. China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science, East China Normal University, Shanghai 200240, P.R. China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, P.R. China"
            }
        ],
        "venue": "Wireless Communications and Mobile Computing",
        "year": 2009
    },
    "VtSmKmu2": {
        "id": "VtSmKmu2",
        "title": "A CDH-Based Multi-Signature Scheme with Tight Security Reduction",
        "abstract": "An efficient multi-signature scheme secure in the random oracle model is proposed, which is the first multi-signature scheme with tight security reduction to the hardness of computational Diffie-Hellman (CDH) problem. The scheme only needs the proof-of-possession (POP) key registration assumption to prevent the notorious rogue key attacks and obtain existentially unforgeable security against the adaptively chosen message and signing groupattack. Given current state of the art, it is as difficult to solve the CDH problem as it is to solve the DL problem in many groups of cryptographic interest. Thus the scheme with tight security reduction offers substantially better efficiency (for a given level of provable security) than other schemes in the discrete logarithm setting. Moreover, both the size of multi-signature and the computational cost of verification do not increase with the number of actual signers increasing. Therefore, the proposed scheme is efficient and can be conveniently implemented in the current public key infrastructure (PKI) environment.",
        "keywords": [
            "current public key infrastructure",
            "tight security reduction",
            "efficient multi-signature scheme",
            "public key infrastructure",
            "multi-signature",
            "provable security",
            "computational diffie-hellman problem",
            "random oracle model",
            "dl problem",
            "proposed scheme",
            "digital signature",
            "public key cryptography",
            "cdh-based multi-signature scheme",
            "cdh-based multisignature scheme",
            "digital signatures",
            "proof-of-possession key registration",
            "multi-signature scheme",
            "cdh problem",
            "key registration assumption",
            "proof of possession",
            "existentially unforgeable security",
            "discrete logarithm",
            "protocols",
            "games",
            "computational modeling",
            "security",
            "public key"
        ],
        "authors": [
            {
                "name": "Zecheng Wang",
                "org": ""
            },
            {
                "name": "Taozhi Si",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Zhibin Li",
                "org": ""
            }
        ],
        "venue": "ICYCS",
        "year": 2008
    },
    "TzEHDjXK": {
        "id": "TzEHDjXK",
        "title": "Provably Secure Dual-Mode Publicly Verifiable Computation Protocol in Marine Wireless Sensor Networks.",
        "abstract": "In the marine wireless sensor networks, marine sensors collect multidimensional data such as temperature, salinity, dissolved oxygen and chlorophyll concentration in the ocean using a single hardware unit for further statistical analysis. Once these data are collected, they will be sent to the satellites or vessels for scientific information processing purposes, e.g. computing the mean, the variance and making regression analysis. Verifiable computation (VC) always allows the computationally weak parties to execute computing function operations over outsourced data sets or perform data sets towards outsourced functions to the cloud and still provides an efficient way to verify the returned result, which is an important issue in marine wireless sensor networks. However, the oceangoing voyage vessels always have low computational abilities, in such a way that they may outsource some computations (that need expensive computation costs by themselves) to the data center on the land (e.g. cloud). The computational results cannot be used directly since the cloud may return an incorrect outcome for some profits. Hence, we design a secure publicly VC protocol called ({mathcal {DM}}{-}{mathcal {PVC}}), which supports both public delegation and public verifiability properties and tackles outsourced functions and outsourced data sets in a combined way. We additionally prove the proposed ({mathcal {DM}}{-}{mathcal {PVC}}) secure in the random oracle model and evaluate its performance in the end.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": "East China Normal University"
            },
            {
                "name": "Lifei Wei",
                "org": "Shanghai Ocean University"
            },
            {
                "name": "Xiangxue Li",
                "org": "East China Normal University"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University"
            }
        ],
        "venue": "WASA",
        "year": 2017
    },
    "eiUrwyAB": {
        "id": "eiUrwyAB",
        "title": "Antioxidant properties and radical-scavenging activity of ethanol extract of defatted peanut meal",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "youwei zhang",
                "org": ""
            },
            {
                "name": "hui zhang",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "xiaona guo",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "xiguang qi",
                "org": ""
            }
        ],
        "venue": "International Journal of Food Properties",
        "year": 2012
    },
    "3bJsK5iJ": {
        "id": "3bJsK5iJ",
        "title": "Robust password changing and DoS resilience for human‐centric password authentication",
        "abstract": "In password‐based or two‐factor (password and smart card) authentications, password\n         changing is one of common techniques used to improve the security of the systems protected\n         by the password. However, the password‐changing operations in existing password authentications\n         either depend on the login phase or violate the common practice that an old password\n         should not be valid for subsequent login after being updated. On the other hand, password\n         mistyping is very common in reality, which may be random or be skewed by the adversary\n         via technical means or social engineering manipulation [i.e., a kind of denial‐of‐service\n         (DoS) attack]. In human‐centric authentication mechanisms, password changing and DoS\n         resilience are not marginal issues. The paper addresses the requirements of robust\n         password changing in authentication and presents ",
        "keywords": [
            "password changing",
            "DoS resilience",
            "self‐healing"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China;State Key Laboratory of Integrated Services Networks, Xidian University, Xi'an, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Yu Yu",
                "org": "Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China"
            },
            {
                "name": "Jian Weng",
                "org": "Department of Computer Science, JiNan University, Guangzhou, China"
            },
            {
                "name": "Ziping Wang",
                "org": "Department of Information Science and Systems, Morgan State University, Maryland, U.S.A."
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2014
    },
    "Lfveee3M": {
        "id": "Lfveee3M",
        "title": "Balanced 2p-variable rotation symmetric Boolean functions with optimal algebraic immunity, good nonlinearity, and good algebraic degree",
        "abstract": "In designing cryptographic Boolean functions, it is challenging to achieve at the same time the desirable features of algebraic immunity, balancedness, nonlinearity, and algebraic degree for necessary resistance against algebraic attack, correlation attack, Berlekamp-Massey attack, etc. This paper constructs balanced rotation symmetric Boolean functions on n variables where n=2 p and p is an odd prime. We prove the construction has an optimal algebraic immunity and is of high nonlinearity. We check that, at least for those primes p which are not of the form of a power of two plus one, the algebraic degree of the construction achieves in fact the upper bound n-1. © 2013 Elsevier Ltd.",
        "keywords": [
            "algebraic immunity",
            "boolean function",
            "degree",
            "nonlinearity"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Qifeng Zhou",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            },
            {
                "name": "Yu Yu",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Shaohua Tang",
                "org": "South China University of Technology(South China University of Technology,South China Univ. of Technol.),Guangzhou,China"
            }
        ],
        "venue": "Journal of Mathematical Analysis and Applications",
        "year": 2013
    },
    "XGmCS31Q": {
        "id": "XGmCS31Q",
        "title": "A generalized proxy signature scheme based on the RSA cryptosystem",
        "abstract": "In proxy signature schemes, original signers delegate proxy signers to sign messages on behalf of original signers. Based on the RSA cryptosystem, a generalized proxy signature scheme is proposed. The proposed scheme can resist all of known possible attacks such as forgery attacks. In the random oracle model, the scheme can provide security properties of strong unforgeability, verifiability, strong undeniability, strong identifiability, distinguishability and prevention of misuse of proxy signing right.",
        "keywords": [
            "strong undeniability",
            "strong identifiability",
            "rsa cryptosystem",
            "proxy signature scheme",
            "proxy signer",
            "strong unforgeability",
            "proposed scheme",
            "original signer",
            "generalized proxy signature scheme",
            "proxy signing right",
            "random oracle model"
        ],
        "authors": [
            {
                "name": "Qingshui Xue",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, P.R.C."
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, P.R.C."
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, P.R.C."
            }
        ],
        "venue": "PDCAT",
        "year": 2004
    },
    "wUohVBYa": {
        "id": "wUohVBYa",
        "title": "Impact of copper nanoparticles and ionic copper exposure on wheat (Triticum aestivum L.) root morphology and antioxidant response.",
        "abstract": "Copper nanoparticles (nCu) are widely used in industry and in daily life, due to their unique physical, chemical, and biological properties. Few studies have focused on nCu phytotoxicity, especially with regard to toxicity mechanisms in crop plants. The present study examined the effect of 15.6 μM nCu exposure on the root morphology, physiology, and gene transcription levels of wheat (Triticum aestivum L.), a major crop cultivated worldwide. The results obtained were compared with the effects of exposing wheat to an equivalent molar concentration of ionic Cu (Cu released from CuSO) and to control plants. The relative growth rate of roots decreased to approximately 60% and the formation of lateral roots was stimulated under nCu exposure, possibly due to the enhancement of nitrogen uptake and accumulation of auxin in lateral roots. The expression of four of the genes involved in the positive regulation of cell proliferation and negative regulation of programmed cell death decreased to 50% in the Cu treatment compared to that of the control, while only one gene was down-regulated to about half of the control in nCu treatment. This explained the decreased root cell proliferation and higher extent of induced cell death in Cu- than in nCu-exposed plants. The increased methane dicarboxylic aldehyde accumulation (2.17-fold increase compared with the control) and decreased antioxidant enzyme activities (more than 50% decrease compared with the control) observed in the Cu treatment in relation to the nCu treatment indicated higher oxidative stress in Cu- than in nCu-exposed plants. Antioxidant (e.g., proline) synthesis was pronouncedly induced by nCu to scavenge excess reactive oxygen species, alleviating phytotoxicity to wheat exposed to this form of Cu. Overall, oxidative stress and root growth inhibition were the main causes of nCu toxicity.",
        "keywords": [
            "Cu nanoparticles",
            "CuSO(4)",
            "Oxidative stress",
            "Transcription level",
            "Triticum aestivum L."
        ],
        "authors": [
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300 RA, Leiden, The Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, The Netherlands."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yizhi Ye",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Pengfei Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Benben Du",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2018
    },
    "XBomnd1Z": {
        "id": "XBomnd1Z",
        "title": "Enantioselective damage of diclofop acid mediated by oxidative stress and acetyl-CoA carboxylase in nontarget plant Arabidopsis thaliana.",
        "abstract": "Diclofop-methyl (DM) is a widely used chiral herbicide, which rapidly hydrolyzes to its major metabolite diclofop acid (DC) after application. With a carbon chiral center, DC not only is an important ingredient of herbicidal activity, but also has a long half-life in soil. Studies so far have only considered the activity of racemic DM in target organisms, and the enantioselective toxicity in nontarget plants of DM and DC has yet to be explored. In this study, the enantioselective phytotoxicity of DC mediated by oxidative stress and the key enzyme ACCase in the fatty acid synthesis system on the model plant Arabidopsis thaliana was investigated. Significant differences between the two enantiomers were observed in phytotoxicity including growth inhibition, oxidative damage and alteration of key genes expression of ACCase, with R-DC showing greater toxicity to Arabidopsis thaliana than S-DC. The results of molecular docking showed that there was a stronger affinity between R-DC and the target enzyme carboxyltransferase domain of ACCase, likely leading to the enantioselective phytotoxicity of DC. This study suggested that chirality of both parent compounds and metabolites should be considered to improve our understanding of the environmental fate and risks of chiral pesticides.",
        "keywords": [],
        "authors": [
            {
                "name": "Qiong Zhang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Meirong Zhao",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Tao Lu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Quan Zhang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Weiping Liu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2012
    },
    "JmOtowTb": {
        "id": "JmOtowTb",
        "title": "Diversity, Innovation, and Entrepreneurship in China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "roger r stough",
                "org": ""
            },
            {
                "name": "j yuan",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "l0lSBwgE": {
        "id": "l0lSBwgE",
        "title": "Diuron treatment reveals the different roles of two cyclic electron transfer pathways in photosystem II in Arabidopsis thaliana.",
        "abstract": "Three ecotypes of Arabidopsis thaliana, ecotype Columbia (Wild type, Wt) and two mutants (pgr5 and ndf4), were used to evaluate the effects of diuron on photosynthetic activity of A. thaliana. It was found that diuron adversely affected the fresh weight and chlorophyll content of the plants. Chlorophyll fluorescence studies determined that the pgr5 mutant was more sensitive to diuron than Wt and the ndf4 mutant. Gene expression analysis revealed different roles for the two cyclic electron transfer (CET) pathways, NAD(P)H dehydrogenase (NDH) and proton gradient regulation (PGR5) pathways, in the plant after diuron treatment. For example, a gene in the NDH pathway, lhca5, was activated in the low dose (LD) group in the pgr5 mutant, but was down-regulated in the moderate dose (MD) group, along with two other NDH-related genes (ppl2 and ndhH). In the PGR5 pathway, the pgr5 gene was functional under conditions of increased stress (MD group), and was up-regulated to a greater extent in the ndf4 mutant than that in the Wt and pgr5 mutant. Our results suggest that the PGR5 pathway in plants is more important than the NDH pathway during resistance to environmental stress. Deficiencies in the PGR5 pathway could not be counteracted by the NDH pathway, but deficiencies in the NDH pathway could be overcome by stimulating PGR5.",
        "keywords": [
            "Cyclic electron transfer",
            "Diuron",
            "Photosynthesis",
            "ndf4",
            "pgr5"
        ],
        "authors": [
            {
                "name": "Yujian Jin",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Si Chen",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hao Song",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xingxing Li",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Pesticide biochemistry and physiology",
        "year": 2017
    },
    "cReKcVDy": {
        "id": "cReKcVDy",
        "title": "A Method and Its Implementation for Constructing Bäcklund Transformations to Nonlinear Evolution Equations",
        "abstract": "An algorithmic method to construct a kind of auto Bäcklund transformations (BTs) is proposed. A Maple package AutoBT, which can entirely automatically generate auto BT is presented. AutoBThas been effectively applied to many nonlinear evolution equations with physical significance. Not only are previously known BT recovered but also in some cases new and more general form of BT are obtained.",
        "keywords": [
            "nonlinear evolution equations",
            "maple package",
            "cklund transformation",
            "general form",
            "nonlinear evolution equation",
            "physical significance",
            "auto b",
            "constructing b",
            "auto bt",
            "algorithmic method",
            "cklund transformations"
        ],
        "authors": [
            {
                "name": "Zhibin Li",
                "org": "Institute of Theoretical Computing, and Department of Computer Science, East China Normal University, Shanghai, China 200062"
            },
            {
                "name": "Yinping Liu",
                "org": "Department of Computer Science, East China Normal University, Shanghai, China 200062"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science, East China Normal University, Shanghai, China 200062"
            }
        ],
        "venue": "ASCM",
        "year": 2008
    },
    "iFuqlmmg": {
        "id": "iFuqlmmg",
        "title": "COMPARATIVE STUDY OF CHEMICAL COMPOSITION AND PHYSICOCHEMICAL PROPERTIES OF DEFATTED WHEAT GERM FLOUR AND ITS PROTEIN ISOLATE",
        "abstract": "",
        "keywords": [
            "chemical composition"
        ],
        "authors": [
            {
                "name": "KE-XUE ZHU",
                "org": ""
            },
            {
                "name": "HUI-MING ZHOU",
                "org": ""
            },
            {
                "name": "HAI-FENG QIAN",
                "org": ""
            }
        ],
        "venue": "Journal of Food Biochemistry",
        "year": 2006
    },
    "bTo5Grhc": {
        "id": "bTo5Grhc",
        "title": "Non-interactive CDH-based multisignature scheme in the plain public key model with tighter security",
        "abstract": "A multisignature scheme allows an ad hoc set of users to sign a message so that the resulting single signature certifies that the users endorsed the message. However, all known multisignatures are either at the price of complexity and additional trust of Certificate Authority (CA), or sacrificing efficiency of computation and communication (including both bandwidth and round). This paper proposes a new multisignature scheme with efficient verification in the plain public key model. Our multisignatures enjoys the most desired features: (1) Our plain public key model-based multisignatures do not impose any impractical key setup or PKI requirements; (2) Our multisignature scheme is non-interactive, which saves computation and communication in signature generation; (3) Through pre-computation, our scheme achieves O(1) verification in the plain public key model; (4) Provable tighter security under the standard CDH assumption ensures high level of security in both practice and theory. Hence, our non-interactive multisignatures are of great use in authentication of routes in networks.",
        "keywords": [
            "single signature certifies",
            "new multisignature scheme",
            "multisignature scheme",
            "efficient verification",
            "non-interactive multisignatures",
            "known multisignatures",
            "public key model-based multisignatures",
            "plain public key model",
            "signature generation",
            "tighter security",
            "impractical key setup"
        ],
        "authors": [
            {
                "name": "Yuan Zhou",
                "org": "Department of Computer Science and Technology, East China Normal University and Network Emergency Response Technical Team/Coordination Center, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            },
            {
                "name": "Xiangxue Li",
                "org": "Department of Computer Science and Technology, East China Normal University, China"
            }
        ],
        "venue": "ISC",
        "year": 2011
    },
    "VCtNoTo8": {
        "id": "VCtNoTo8",
        "title": "Fast poisson solvers for thermal analysis",
        "abstract": "Accurate and efficient thermal analysis for a VLSI chip is crucial, both for sign-off reliability verification and for design-time circuit optimization. To determine an accurate temperature profile, it is important to simulate a die together with its thermal mounts: this requires solving Poisson's equation on a nonrectangular 3D domain. This article presents a class of eigendecomposition-based Fast Poisson Solvers (FPS) for chip-level thermal analysis. We start with a solver that solves a rectangular 3D domain with mixed boundary conditions in O(N⋅ logN) time, where N is the dimension of the finite difference matrix. Then we reveal, for the first time in the literature, a strong relation between fast Poisson solvers and Green-function-based methods. Finally, we propose an FPS method that leverages the preconditioned conjugate gradient method to solve nonrectangular 3D domains efficiently. We demonstrate this approach on thermal analysis of an industrial microprocessor, showing accurate results verified by a commercial tool, and that it solves a system of dimension 4.54e6 in only 13 conjugate gradient iterations, with a runtime of 65 seconds, a 15X speedup over the popular ICCG solver.",
        "keywords": [
            "thermal analysis",
            "accurate temperature profile",
            "chip-level thermal analysis",
            "fast poisson solvers",
            "eigendecomposition-based fast poisson solvers",
            "fps method",
            "poisson solvers",
            "efficient thermal analysis",
            "accurate result",
            "thermal mount",
            "green-function-based method",
            "green function"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "IBM T. J. Watson Research Center, NY"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "University of Minnesota, MN"
            },
            {
                "name": "Eren Kursun",
                "org": "IBM T. J. Watson Research Center, NY"
            }
        ],
        "venue": "ACM Trans. Design Autom. Electr. Syst.",
        "year": 2012
    },
    "rZmdBgUI": {
        "id": "rZmdBgUI",
        "title": "The effect of oat β-glucan on in vitro glucose diffusion and glucose transport in rat small intestine.",
        "abstract": "Many previous studies have reported the role of oat β-glucan (OBG) in the reduction of postprandial glucose, and hypothesised that OBG may form a protective layer along the intestinal wall, acting as a viscous barrier to decrease glucose transportation. This study examined whether the molecular weight (MW) and concentration of OBG affected the diffusion of glucose in vitro. The effect of OBG on glucose transportation in vitro and sodium-potassium adenosine triphosphatase (Na(+) /K(+) -ATPase) activity in the everted small intestines of normal rats was also examined.In vitro, higher MWs and concentrations of OBG, increased the inhibitory effects on glucose diffusion and glucose adsorption. The transport of glucose by glucose transporters and Na(+) /K(+) -ATPase activity in the small intestinal mucosa of rats were significantly lower following the addition of OBG than those in the absence of OBG at the same time-points throughout glucose transportation (P < 0.05). In the OBG-treated group, the Na(+) /K(+) -ATPase activity decreased with increasing OBG MW. However, as the concentration of OBG in the solution increased, the Na(+) /K(+) -ATPase activity in the small intestine increased due to stronger gastrointestinal motility. We also found that higher MWs of OBG had a greater inhibitory effect on intestinal disaccharidase activities in vitro.Oat β-glucan is able to adsorb glucose molecules, inhibit glucose transport, decrease the concentration of available glucose and suppress disaccharidase activities in the small intestine.",
        "keywords": [
            "na+/k+-atpase",
            "disaccharidase",
            "glucose adsorption",
            "glucose transport",
            "oat β-glucan",
            "na k atpase"
        ],
        "authors": [
            {
                "name": "Yu Zhang",
                "org": "Jiangnan University, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China; Jiangnan University, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Xiguang Qi",
                "org": ""
            },
            {
                "name": "Xiangli Ding",
                "org": ""
            },
            {
                "name": "Bo Hu",
                "org": ""
            },
            {
                "name": "Jiajia Li",
                "org": ""
            }
        ],
        "venue": "Journal of the science of food and agriculture",
        "year": 2015
    },
    "mcLnLT3o": {
        "id": "mcLnLT3o",
        "title": "Evaluation of the taxonomic and functional variation of freshwater plankton communities induced by trace amounts of the antibiotic ciprofloxacin.",
        "abstract": "Ciprofloxacin (CIP), one of the most frequently detected antibiotics in water systems, has become an aquatic contaminant because of improper disposal and excretion by humans and animals. It is still unknown how trace amounts of CIP affect the aquatic microbial community diversity and function. We therefore investigated the effects of CIP on the structure and function of freshwater microbial communities via 16S/18S rRNA gene sequencing and metatranscriptomic analyses. CIP treatment (7 μg/L) did not significantly alter the physical and chemical condition of the water body as well as the composition of the main species in the community, but slightly increased the relative abundance of cyanobacteria and decreased the relative abundance of eukaryotes. Metatranscriptomic results showed that bacteria enhanced their phosphorus transport and photosynthesis after CIP exposure. The replication, transcription, translation and cell proliferation were all suppressed in eukaryotes, while the bacteria were not affected in any of these aspects. This interesting phenomenon was the exact opposite to both the antibacterial property of CIP and its safety for eukaryotes. We hypothesize that reciprocal and antagonistic interactions in the microcosm both contribute to this result: cyanobacteria may enhance their tolerance to CIP through benefiting from cross-feeding and some secreted substances that withstand bacterial CIP stress would also affect eukaryotic growth. The present study thus indicates that a detailed assessment of the aquatic ecotoxicity of CIP is essential, as the effects of CIP are much more complicated in microbial communities than in monocultures. CIP will continue to be an environmental contaminant due to its wide usage and production and more attention should be given to the negative effects of antibiotics as well as other bioactive pollutants on aquatic environments.",
        "keywords": [
            "Ciprofloxacin",
            "Cyanobacteria",
            "Freshwater microbiome",
            "High-throughput sequencing",
            "Meta-transcriptomic analysis"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, RA, Leiden 2300, the Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, the Netherlands."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Tingzhang Wang",
                "org": "Key laboratory of microbial technology and bioinformatics of Zhejiang Province, Hangzhou 310012, China."
            },
            {
                "name": "Jun Chen",
                "org": "College of Biological and Environmental Engineering, Zhejiang Shuren University, Hangzhou 310021, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environment international",
        "year": 2019
    },
    "pBy43J0d": {
        "id": "pBy43J0d",
        "title": "The effects of phosphate salts on the pasting, mixing and noodle-making performance of wheat flour.",
        "abstract": "The effects of five phosphate salts (PS) on the pasting properties of flour, mixing properties of dough and qualities of cooked noodles were investigated. Rapid Visco Analysis showed that all types of PS increased the peak and final viscosities of wheat flour. Trisodium phosphate (TSP) significantly increased pasting temperature with increasing concentration. The Farinograph characteristics indicated that TSP markedly increased stability time and progressively decreased the degree of softening of the dough. The cooking yield of the TSP, sodium pyrophosphate (TSPP) and disodium phosphate (DSP) groups clearly increased, and the cooking loss was reduced by adding 0.3% sodium tripolyphosphate (STPP), 0.1% TSPP or 0.1% TSP. Texture profile analysis revealed that the hardness of cooked noodles from STPP and TSP groups slightly decreased, while that of TSPP and DSP groups decreased significantly. Overall, PS improved the qualities of noodles mainly by promoting starch gelatinization and strengthening the gluten network.",
        "keywords": [
            "Pasting property",
            "Phosphate salt",
            "Sulfhydryl group",
            "Texture profile analysis",
            "Wheat noodle"
        ],
        "authors": [
            {
                "name": "Min Chen",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "nPYRsMmc": {
        "id": "nPYRsMmc",
        "title": "Radiometric quality assessment of GOES-16 ABI L1b images.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhipeng Wang",
                "org": ""
            },
            {
                "name": "Xiangqian Wu",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Fangfang Yu",
                "org": ""
            },
            {
                "name": "Robert Iacovazzi",
                "org": ""
            },
            {
                "name": "Xi Shao",
                "org": ""
            },
            {
                "name": "Vladimir Kondratovich",
                "org": ""
            },
            {
                "name": "Hyelim Yoo",
                "org": ""
            }
        ],
        "venue": "Earth Observing Systems",
        "year": 2018
    },
    "ExMDehMI": {
        "id": "ExMDehMI",
        "title": "Feedback regulation between aquatic microorganisms and the bloom-forming cyanobacterium Microcystis aeruginosa .",
        "abstract": "The frequency and intensity of cyanobacterial blooms are increasing worldwide. Interactions between toxic cyanobacteria and aquatic microorganisms need to be critically evaluated to understand microbial drivers and modulators of the blooms. In this study, we applied 16S/18S rRNA gene sequencing and metabolomics analyses to measure the microbial community composition and metabolic responses of the cyanobacterium  in a coculture system receiving dissolved inorganic nitrogen and phosphorus (DIP) close to representative concentrations in Lake Taihu, China.  secreted alkaline phosphatase using a DIP source produced by moribund and decaying microorganisms when the P source was insufficient. During this process,  accumulated several intermediates in energy metabolism pathways to provide energy for its sustaining high growth rates, and increased intracellular sugars to enhance its competitive capacity and ability to defend itself against microbial attack. It also produced a variety of toxic substances, including microcystins, to inhibit metabolite formation via energy metabolism pathways of aquatic microorganisms, leading to a negative effect on bacterial and eukaryotic microbial richness and diversity. Overall, compared with the monoculture system, the growth of  was accelerated in coculture, while the growth of some cooccurring microorganisms was inhibited; with the diversity and richness of eukaryotic microorganisms being more negatively impacted than prokaryotic microorganisms. These findings provide valuable information for clarifying how  can potentially modulate its associations with other microorganisms, with ramifications for its dominance in aquatic ecosystems. This study we measure the microbial community composition and metabolic responses of  in a microcosms coculture system receiving dissolved inorganic nitrogen and phosphorus (DIP) close to the average concentrations in Lake Taihu. In the coculture system DIP is depleted, and growth and production of aquatic microorganisms can be stressed by a lack of DIP availability.  could accelerate its growth via interactions with specific cooccurring microorganisms, and the accumulation of several intermediates in energy metabolism-related pathways. Furthermore,  can decrease carbohydrate metabolism of cooccurring aquatic microorganisms and thus disrupt microbial activities in the coculture. This also had a negative effect on bacterial and eukaryotic microbial richness and diversity. Microcystin was capable of decreasing the biomass of total phytoplankton in aquatic microcosms. Overall, compared with the monoculture, the growth of total aquatic microorganisms is inhibited, with the diversity and richness of eukaryotic microorganisms being more negatively impacted than prokaryotic microorganisms. The only exception is  in the coculture system, whose growth was accelerated.",
        "keywords": "",
        "authors": [
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China."
            },
            {
                "name": "Hans W Paerl",
                "org": "College of Environment, Hohai University, Nanjing, 210098, P.R. China."
            },
            {
                "name": "Yiling Chen",
                "org": "Department of Civil, Environmental, and Geo- Engineering, University of Minnesota, Minneapolis, MN, 55455-0116, USA."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, P.R. China hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Applied and environmental microbiology",
        "year": 2019
    },
    "Gx3EhvS3": {
        "id": "Gx3EhvS3",
        "title": "Security analysis and improvement of digital multi-signature on the generalized conic curve",
        "abstract": "In this paper we present the security analysis on a multi-signature scheme based on the generalized conic curve (Lin-Wang-Li protocol) is presented, which exist the severe forgery problems. The security of the scheme is not based on any difficult issues such as the discrete logarithms on the generalized conic curve or the hardness of integer factoring. An adversary can forge the signature without solving any hard problems. In order to solve the existing problems, we improve the scheme is improved and a present our multi-signature scheme on the generalized conic curve is presented.",
        "keywords": [
            "Digital signature",
            "Discrete logarithms",
            "Forgery attacks",
            "Generalized conic curve",
            "Multi-signature protocol"
        ],
        "authors": [
            {
                "name": "Li Ding",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China(National Computer Network Emergency Response Technical Team,National Computer Network Emergency Response Technical Team/Coordination Center of China),Beijing,China"
            },
            {
                "name": "Yuan Zhou",
                "org": "National Computer Network Emergency Response Technical Team/Coordination Center of China(National Computer Network Emergency Response Technical Team,National Computer Network Emergency Response Technical Team/Coordination Center of China),Beijing,China"
            },
            {
                "name": "QIAN Hai-feng",
                "org": "East China Normal University(East China Normal University),Shanghai,China"
            }
        ],
        "venue": "Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology",
        "year": 2010
    },
    "FmVRqMlz": {
        "id": "FmVRqMlz",
        "title": "Membrane‐disruptive property of a novel antimicrobial peptide from anchovy (Engraulis japonicus) hydrolysate",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wenting tang",
                "org": "jiangnan university"
            },
            {
                "name": "hui zhang",
                "org": "jiangnan university"
            },
            {
                "name": "li wang",
                "org": "jiangnan university"
            },
            {
                "name": "haifeng qian",
                "org": "jiangnan university"
            }
        ],
        "venue": "International Journal of Food Science and Technology",
        "year": 2014
    },
    "gK5SOZJD": {
        "id": "gK5SOZJD",
        "title": "A new threshold proxy signature scheme from bilinear pairings",
        "abstract": "Based on the GDH signature (short signature scheme) a probabilistic signature scheme is proposed in this paper with security\n proof. Then a new threshold proxy signature from bilinear pairings is proposed as well by using the new probabilistic signature\n scheme and the properties of the Gap Diffie-Hellman (GDH) group (where the Computational Diffie-Hellman problem is hard but\n the Decisional Diffie-Hellman problem is easy to solve). Our constructions are based on the recently proposed GDH signature\n scheme of Bonel et al.’s article. Bilinear pairings could be built from Weil pairing or Tate pairing. So most our constructions\n would be simpler, but still with high security. The proposed threshold proxy signature is the first one which is built from\n bilinear pairings. At the end of this paper security and performance of the threshold proxy signature scheme is also analyzed.",
        "keywords": [
            "probabilistic signature scheme",
            " threshold proxy signature",
            " VSS",
            " bilinear pairings"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science,Shanghai Jiao Tong University,Shanghai,China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Department of Computer Science,Shanghai Jiao Tong University,Shanghai,China"
            },
            {
                "name": "Qingshui Xue",
                "org": "Department of Computer Science,Shanghai Jiao Tong University,Shanghai,China"
            }
        ],
        "venue": "Science in China Series F: Information Sciences",
        "year": 2004
    },
    "ryvaHhjh": {
        "id": "ryvaHhjh",
        "title": "A Searchable Asymmetric Encryption Scheme with Support for Boolean Queries for Cloud Applications.",
        "abstract": "Cloud computing is a new promising technology paradigm that can provide clients from the whole network with scalable storage resources and on-demand high-quality services. However, security concerns are raised when sensitive data are outsourced. Searchable encryption is a kind of cryptographic primitive that enables clients to selectively retrieve encrypted data, the existing schemes that support ...",
        "keywords": [
            "data security",
            "searchable encryption",
            "boolean query",
            "cloud security"
        ],
        "authors": [
            {
                "name": "Ming Zeng",
                "org": ""
            },
            {
                "name": "Kai Zhang",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Xiaofeng Chen",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            }
        ],
        "venue": "The Computer Journal",
        "year": 2019
    },
    "5IBcrLS7": {
        "id": "5IBcrLS7",
        "title": "Enantioselective phytotoxicity of the herbicide imazethapyr and its effect on rice physiology and gene transcription.",
        "abstract": "Imazethapyr (IM) is a chiral herbicide and a widely used racemic mixture. This report investigated the enantioselectivity between R- and S-IM in rice and explored its causative mechanism at the physiological and molecular levels. The results suggested that R-IM inhibited acetolactate synthase (ALS) activity to a greater extent than S-IM, which reduced the synthesis of branched-chain amino acids (BCAAs). Additionally, most other amino acids showed enantioselectivity. On the cellular level, R-IM showed stronger toxicity against protoplasts than S-IM. A gene transcription profile analysis showed that gene transcripts in many metabolic pathways, including amino acid metabolism, photosynthesis, starch and sugar metabolism, and the tricarboxylic acid cycle displayed enantioselectivity between the IM enantiomers. R-IM regulated more genes more strongly than S-IM. This study suggested that R-IM has stronger toxicity against plants than S-IM; this toxicity is caused not only by changing targeted enzyme activity and amino acid synthesis, but also by affecting gene transcription in other metabolic pathways directly or indirectly in an enantioselective manner.",
        "keywords": [],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Ruiqin Wang",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Haijia Hu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Tao Lu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xinliang Chen",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Hanqi Ye",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Weiping Liu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2011
    },
    "ChaZEEDh": {
        "id": "ChaZEEDh",
        "title": "Investigation on molecular and morphology changes of protein and starch in rice kernel during cooking.",
        "abstract": "The composition and structure of starch are important indicators to evaluate the quality of rice, but the effect of protein on structural properties of rice has always been controversial. In the present study, the rheological properties and thermal properties were combined to investigate the effects of protein on mechanical and inner structure changes of rice kernel during cooking. The morphologic changes in overall form and inner structure of the kernel showed the limited and uneven gelatinization of starch, and reflected the good heating stability of protein. The comparison of molecular mobility in HO/DO reflected the special gelatinization behavior of starch and the hydrophobicity of protein during cooking. The similar proton distributions between starch, starch-protein mixture and rice flour indicated the weak interactions between starch and protein. The results of Fourier transform infrared spectra, thermogravimetric analysis and transmission electron microscope confirmed the wrapping effect of starch and surface interactions with protein.",
        "keywords": [
            "Cooking",
            "Molecular changes",
            "Morphology",
            "Protein",
            "Rice",
            "Starch"
        ],
        "authors": [
            {
                "name": "Ling Zhu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Lilin Cheng",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China. Electronic address: zhanghui@jiangnan.edu.cn."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, China."
            }
        ],
        "venue": "Food chemistry",
        "year": 2020
    },
    "CK6KsPJA": {
        "id": "CK6KsPJA",
        "title": "Cryptanalysis and Improvement on An ID-Based Key Issuing Protocol",
        "abstract": "In this paper we analyze an ID-based key issuing protocol due to Gangishetti et al., designed for eliminating the need of secure channel between PKG and users and avoiding the key escrow problem. Their protocol consists of five sub-protocols, namely system setup, system public key setup, key issuing, key securing and key retrieving. We show that both the key issuing and the key securing sub-protocols suffer from impersonation attacks. Further, we present an improved key issuing protocol which is proved to be secure against adaptive chosen message attack in the random oracle model under the CDH assumption",
        "keywords": [
            "protocols",
            "system setup",
            "key issuing",
            "key securing subprotocols",
            "id-based key issuing protocol",
            "cryptanalysis",
            "telecommunication channels",
            "key retrieving protocol",
            "secure channel",
            "key securing",
            "id-based key issuing",
            "random oracle model",
            "key issuing protocol",
            "key escrow problem",
            "public key cryptography",
            "impersonation attack",
            "digital signatures",
            "id-based key",
            "improved key",
            "message attack",
            "telecommunication security",
            "key retrieving",
            "system public key setup",
            "message switching",
            "system public key setup protocol",
            "system setup protocol",
            "key securing protocol",
            "privacy",
            "distributed computing",
            "public key",
            "security",
            "computer science",
            "cryptography",
            "elliptic curve cryptography",
            "cryptographic protocols"
        ],
        "authors": [
            {
                "name": "Licheng Wang",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Feng Cao",
                "org": "Shanghai Jiao Tong University, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Shanghai Jiao Tong University, China"
            }
        ],
        "venue": "IMSCCS (2)",
        "year": 2006
    },
    "TRiQwg83": {
        "id": "TRiQwg83",
        "title": "Democratic group signatures with threshold traceability",
        "abstract": "This paper presents a concrete democratic group signature scheme which holds (t, n)-threshold traceability. In the scheme, the capability of tracing the actual signer is distributed among n group members. It gives a valid democratic group signature such that any subset with more than t members can jointly reconstruct a secret and reveal the identity of the signer. Any active adversary cannot do this even\n if he can corrupt up to t − 1 group members.",
        "keywords": [
            "traceability",
            "threshold traceability clc number: tp 309 document code: a",
            "democratic group signature dgs",
            "anonymity"
        ],
        "authors": [
            {
                "name": "Xiang-xue Li",
                "org": "Shanghai Jiaotong University School of Information Security Engineering Shanghai 200240 China"
            },
            {
                "name": "Hai-feng Qian",
                "org": "East China Normal University Computer Science and Technology Department Shanghai 200241 China"
            },
            {
                "name": "Jian-hua Li",
                "org": "Shanghai Jiaotong University School of Information Security Engineering Shanghai 200240 China"
            }
        ],
        "venue": "Journal of Shanghai Jiaotong University (science)",
        "year": 2009
    },
    "DR25dp84": {
        "id": "DR25dp84",
        "title": "Ammonium reduces chromium toxicity in the freshwater alga Chlorella vulgaris.",
        "abstract": "The aim of the present study was to investigate the protective effect of ammonium (NH4 (+)) on Cr toxicity to the freshwater alga Chlorella vulgaris. We followed an array of cellular functions and biomolecules in C. vulgaris cells exposed to 50 or 100 μM Cr at three different initial NH4 (+) concentrations (0.5, 3, and 10 mM). The results showed that Cr strongly inhibited cell yield of C. vulgaris, but 10 mM NH4 (+) could decrease by more than two-fold Cr toxicity on cell yield compared to exposure to 0.5 mM NH4 (+). Cr toxicity on gene transcripts and cellular substructure was also much lower at high than at low NH4 (+). Our results suggest that this protecting effect of NH4 (+) on intracellular Cr toxicity could be due to several factors, such as enhance uptake of phosphorus, increase in C and N assimilation efficiency, and increase transcription of photosynthesis-related genes.",
        "keywords": [
            "Chromium",
            " Nitrogen",
            " Chlorella vulgaris",
            " Gene transcript",
            " Subcellular structure"
        ],
        "authors": [
            {
                "name": "Jingqing Liu",
                "org": "College of Civil Engineering and Architecture, Zhejiang University, Hangzhou, 310027, People's Republic of China."
            },
            {
                "name": "Zhengqi Sun",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint ULaval-CNRS International Research Unit,Université Laval,Québec,Canada"
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Xiaocui Bai",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Applied microbiology and biotechnology",
        "year": 2015
    },
    "IjXvM6dq": {
        "id": "IjXvM6dq",
        "title": "Non-interactive editable signatures for assured data provenance",
        "abstract": "In order to make people truly benefit from data sharing, we need technical solutions to assuring the trustworthiness of data received from parties one may not have encountered in the past. Assured data provenance is an important means for this purpose because it (i) allows data providers to get credited for their contribution or sharing of data, (ii) is able to hold the data providers accountable for the data they contributed, and (iii) enables the data providers to supply high-quality data in a self-healing fashion. While the above (i) and (ii) have been investigated to some extent, the above (iii) is a new perspective that, to our knowledge, has not been investigated in the literature. In this paper, we introduce a novel cryptographic technique that can simultaneously offer these properties. Our technique is called editable signatures, which allow a user, Bob, to edit (e.g., replace, modify, and insert) some portions of the message that is contributed and signed by Alice such that the resulting edited message is jointly signed by Alice and Bob in some fashion. While it is easy to see that the above (i) and (ii) are achieved, the above (iii) is also achieved because Bob may have a better knowledge of the situation that allows him to provide more accurate/trustworthy information than Alice, who may intentionally or unintentionally enter inaccurate or even misleading data into an information network. This is useful because Alice's inaccurate or even misleading information will never be released into an information network if it can be ``cleaned\" or \"healed\" by Bob. Specifically, we propose two novel cryptographic constructions that can be used to realize the above functions in some practical settings.",
        "keywords": [
            "misleading data",
            "trustworthy information",
            "better knowledge",
            "misleading information",
            "data provider",
            "novel cryptographic construction",
            "edited message",
            "assured data provenance",
            "high-quality data",
            "information network",
            "non-interactive editable signature",
            "digital signatures",
            "digital signature"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "East China Normal University, Shanghai, China"
            },
            {
                "name": "Shouhuai Xu",
                "org": "University of Texas at San Antonio, San Antonio, USA"
            }
        ],
        "venue": "CODASPY",
        "year": 2011
    },
    "pKOYTb4n": {
        "id": "pKOYTb4n",
        "title": "Cryptanalysis of Li-Tzeng-Hwang's improved signature schemes based on factoring and discrete logarithms",
        "abstract": "Laih and Kuo proposed two efficient signature schemes based on discrete logarithms and factorization. Recently, Li et al. improve one of their schemes in order to use fewer keys for a signing document. In this paper, we shall prove that their improvement of Laih and Kuo's signature scheme is insecure. Moreover the improved signature scheme in fact is not based on two cryptographic assumptions simultaneously, and forging a signature on any message would not need to solve any difficult problems.",
        "keywords": [
            "difficult problem",
            "cryptanalysis",
            "signing document",
            "factoring",
            "improved signature scheme",
            "signature scheme",
            "discrete logarithms",
            "fewer key",
            "digital signature",
            "cryptography",
            "cryptographic assumption",
            "efficient signature scheme",
            "discrete logarithm"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Electrical and Information Engineering, Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashang Road, Shanghai 200030, People's Republic of China"
            },
            {
                "name": "Zhenfu Cao",
                "org": "Electrical and Information Engineering, Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashang Road, Shanghai 200030, People's Republic of China"
            },
            {
                "name": "Haiyong Bao",
                "org": "Electrical and Information Engineering, Department of Computer Science and Engineering, Shanghai Jiao Tong University, 1954 Huashang Road, Shanghai 200030, People's Republic of China"
            }
        ],
        "venue": "Applied Mathematics and Computation",
        "year": 2005
    },
    "6gQlhlrm": {
        "id": "6gQlhlrm",
        "title": "CONVERGED LARGE BLOCK AND STRUCTURED SYNTHESIS FOR HIGH PERFORMANCE MICROPROCESSOR DESIGNS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "minsik cho",
                "org": ""
            },
            {
                "name": "victor kravets",
                "org": ""
            },
            {
                "name": "smita krishnaswamy",
                "org": ""
            },
            {
                "name": "dorothy kucar",
                "org": ""
            },
            {
                "name": "jagannathan narasimhan",
                "org": ""
            },
            {
                "name": "ruchir puri",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "haoxing ren",
                "org": ""
            },
            {
                "name": "chin ngai sze",
                "org": ""
            },
            {
                "name": "louise h trevillyan",
                "org": ""
            },
            {
                "name": "hua xiang",
                "org": ""
            },
            {
                "name": "matthew m ziegler",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "QScP4Xcs": {
        "id": "QScP4Xcs",
        "title": "Physiological and Molecular Response of Arabidopsis thaliana to CuO Nanoparticle (nCuO) Exposure.",
        "abstract": "The widespread application of copper oxide nanoparticles (nCuO) results in ecological risk when nanoparticles enter the environment. This study clarifies the mechanism of nCuO toxicity in Arabidopsis thaliana seedlings via comparison with copper (Cu) ion bioeffects. Under the same culture conditions, Cu(2+) ion exposure exerted a stronger inhibitory effect on plant fresh weight and growth and caused stronger oxidative disruption (measured by malondialdehyde, MDA) than nCuO exposure. The Cu(2+) ions also showed a stronger induction effect than did nCuO on the activity of antioxidant enzymes and the transcription of antioxidant-related genes. Dissolved Cu(2+) ions contributed a minority of the toxicity of nCuO, implying that nCuO itself showed relative strong phytotoxicity. The work presented here will help increase our understanding of the toxicity of metal nanoparticles in plants.",
        "keywords": [
            "Antioxidant gene",
            "Arabidopsis thaliana",
            "Copper oxide nanoparticle (nCuO)",
            "Phytotoxicity"
        ],
        "authors": [
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Hailiqieguli Gumai",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Junjie Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China. hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2017
    },
    "VbBYhFbT": {
        "id": "VbBYhFbT",
        "title": "Buffer-aided secure two-hop communications with adaptive link selection and on/off power control.",
        "abstract": "This paper investigates the link selection policy for secure communications over a buffer-aided two-hop communication link. It is assumed that a source wishes to send information to a destination with the aid of a trusted half-duplex relay node compromised by a passive eavesdropper, and that there is no direct link between the source and the destination. The buffer-aided relay forwards the information to the destination by employing the decode-and-forward (DF) scheme. Both the source and the relay transmissions are assumed to be vulnerable to the eavesdropper. The perfect channel side information (CSI) of the network is assumed to be available at the source and the relay. A link selection policy with on/off power control that both the source and the relay transmit with fixed transmission power levels is derived. It is shown to achieve near-optimal performance as the average transmission power levels at both the source and the relay approach to infinity. A low complexity and asymptotically optimal on/off power control joint link selection is then proposed. Numerical results demonstrate that the proposed link selection policy with on/off power control can achieve superior performance over constant power link selection policies. Overall, the impact of on/off power control on the performance of buffer-aided secure communication over two-hop systems is characterized.",
        "keywords": "",
        "authors": [
            {
                "name": "Jing Wan",
                "org": "School of Information Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Deli Qiao",
                "org": "School of Information Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "WCSP",
        "year": 2017
    },
    "io5u8sCE": {
        "id": "io5u8sCE",
        "title": "A novel green synthesis approach for natural bluish-violet pigments derived from water extracts of Vaccinium bracteatum Thunb. leaves",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Weijia Lian",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Mingcong Fan",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Tingting Li",
                "org": "Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, China"
            },
            {
                "name": "Xuetong Zhang",
                "org": "Affiliated hospital of Jiangnan University (Wuxi No. 4 People’s Hospital), Jiangnan University, Wuxi, 214062, China"
            },
            {
                "name": "Zhiming Rao",
                "org": "School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Yan Li",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Hui Zhang",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Xiguang Qi",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Li Wang",
                "org": "School of Food Science and Technology, State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            }
        ],
        "venue": "Industrial Crops and Products",
        "year": 2019
    },
    "GmQdObwr": {
        "id": "GmQdObwr",
        "title": "Fast and accurate statistical criticality computation under process variations",
        "abstract": "With ever-shrinking device geometries, process variations play an increased role in determining the delay of a digital circuit. Under such variations, a gate may lie on the critical path of a manufactured die with a certain probability, called the criticality probability. In this paper, we present a new technique to compute the statistical criticality information in a digital circuit under process variations by linearly traversing the edges in its timing graph and dividing it into \"zones.\" We investigate the sources of error in using tightness probabilities for criticality computation with Clark's statistical maximum formulation. The errors are dealt with using a new clustering-based pruning algorithm which greatly reduces the size of circuit-level cutsets improving both accuracy and runtime over the current state of the art. On large benchmark circuits, our clustering algorithm gives about a 250× speedup compared with a pairwise pruning strategy with similar accuracy in results. Coupled with a localized sampling technique, errors are reduced to around 5% of Monte Carlo simulations with large speedups in runtime.",
        "keywords": [
            "certain probability",
            "digital circuit",
            "large speedup",
            "process variation",
            "statistical criticality information",
            "criticality computation",
            "criticality probability",
            "clustering algorithm",
            "accurate statistical criticality computation",
            "localized sampling technique",
            "large benchmark circuit"
        ],
        "authors": [
            {
                "name": "Hushrav D. Mogal",
                "org": "Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN"
            },
            {
                "name": "Haifeng Qian",
                "org": "IBM Research, Yorktown Heights, NY"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN"
            },
            {
                "name": "Kia Bazargan",
                "org": "Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN"
            }
        ],
        "venue": "IEEE Trans. on CAD of Integrated Circuits and Systems",
        "year": 2009
    },
    "7lW1TQwG": {
        "id": "7lW1TQwG",
        "title": "The interactive effects of diclofop-methyl and silver nanoparticles on Arabidopsis thaliana: Growth, photosynthesis and antioxidant system.",
        "abstract": "Diclofop-methyl (DM), a common post-emergence herbicide, is frequently used in agricultural production. Silver nanoparticles (AgNPs) are one of the most widely used nanoparticles, and as such, have been detected and monitored in several environmental systems. Here we investigated the interactive effects of DM and AgNPs on the physiological morphology, photosynthesis and antioxidant system of Arabidopsis thaliana. Our results demonstrated that a 1.0 mg/L DM treatment had no significant effect on the fresh weight of plant shoots and the content of total chlorophyll and anthocyanin. However, a 0.5 mg/L AgNPs treatment was found to significantly inhibit plant growth and chlorophyll synthesis, and was found to cause more severe oxidative damage in plants compared to the effects observed in a hydroponic suspension in which DM and AgNPs were jointly present. Meanwhile, the relative transcript levels of photosynthesis related genes (psbA, rbcL, pgrl1A and pgrl1B) in the combined group were found to be slightly increased compared to transcript levels in the AgNPs group, in order to maintain ATP generation at relatively normal levels in order to repair light damage. One explanation for these observed antagonistic effects was that the existence of DM affects the stability of AgNPs and reduced Ag release from AgNPs in the mixed solution. Thereupon, the Ag-content was found to decrease in shoots and roots in the combined group by 15.2% and 9.4% respectively, compared to the AgNPs group. The coexistence of herbicides and nanomaterials in aquatic environments or soil systems will continue to exist due to their wide usages. Our current study highlights that the antagonistic effects between DM and AgNPs exerted a positive impact on A. thaliana growth.",
        "keywords": [
            "Antioxidant system",
            "Combined exposure",
            "Diclofop-methyl",
            "Photosynthesis",
            "Silver nanoparticles"
        ],
        "authors": [
            {
                "name": "Xingxing Li",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300 RA Leiden, The Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, Bilthoven, The Netherlands."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnological and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnological and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2018
    },
    "MKuCVK0f": {
        "id": "MKuCVK0f",
        "title": "A new extracellular von Willebrand A domain-containing protein is involved in silver uptake in Microcystis aeruginosa exposed to silver nanoparticles.",
        "abstract": "Silver nanoparticles (AgNPs) can be toxic for cyanobacteria when present at low nanomolar concentrations, but the molecular mechanisms whereby AgNPs (or free Ag(+) released from AgNPs) interact with these prokaryotic algal cells remain elusive. Here, we studied Ag uptake mechanisms in the prokaryotic cyanobacterium Microcystis aeruginosa exposed to AgNPs by measuring growth inhibition in the absence or presence of high-affinity Ag-binding ligands and by genetic transformation of E. coli with a protein predicted to be involved in Ag uptake. We discovered a new von Willebrand A (vWA) domain-containing protein in M. aeruginosa that mediates Ag uptake from AgNPs when expressed in E. coli. This new Ag transport protein, which is absent in eukaryotic algae, is a potential candidate explaining the higher AgNPs toxicity in cyanobacteria such as M. aeruginosa than that in eukaryotic algae. The present study provides new insights on Ag uptake mechanisms in the prokaryotic algae M. aeruginosa. ",
        "keywords": [
            "Genetic transformation",
            "Microcystis aeruginosa",
            "Silver nanoparticle.vWA domain-containing protein"
        ],
        "authors": [
            {
                "name": "Si Chen",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Yujian Jin",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "Haiping Lu",
                "org": "College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, People's Republic of China."
            },
            {
                "name": "Kun Zhu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China. hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Applied microbiology and biotechnology",
        "year": 2016
    },
    "d6djwpvA": {
        "id": "d6djwpvA",
        "title": "GOES-16 Advanced Baseline Imager instrument performance monitor",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Robbie Iacovazzi",
                "org": "GST, Inc., Greenbelt, Maryland"
            },
            {
                "name": "Haifeng Qian",
                "org": "GST, Inc., Greenbelt, Maryland"
            },
            {
                "name": "Xiangqian Wu",
                "org": "NOAA/NESDIS/STAR, College Park, Maryland"
            },
            {
                "name": "Xi Shao",
                "org": "University of Maryland College, Park, Maryland"
            },
            {
                "name": "Fangfang Yu",
                "org": "GST, Inc., Greenbelt, Maryland"
            }
        ],
        "venue": "Journal of Applied Remote Sensing",
        "year": 2020
    },
    "58u6yIVs": {
        "id": "58u6yIVs",
        "title": "Comparative investigation on metabolite changes in 'wu mi' production by Vaccinium bracteatum Thunb. leaves based on multivariate data analysis using UPLC-QToF-MS.",
        "abstract": "Vaccinium bracteatum Thunb. leaves (VBTL) are used to juicing and dye rice to produce 'Wu mi', which displays a deep blue color. However, little information is known about the formation mechanism of the pigments. In this research, non-targeted metabolic profiling of VBTL and VBTL juice samples at different growth stages was studied for searching the pigment precursors through UPLC-QToF-MS and multivariate data analysis. The results showed the L and b values of 'Wu mi' produced by spring leaves (stages of 2WAB, 4WAB and 6WAB) were significantly lower than other growth stages. Principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) of the VBTL and VBTL juice samples showed distinct classifications. Further variable importance in projection (VIP) plot in PLS-DA model demonstrated the discriminatory potential biomarkers between VBTL and VBTL juice samples. Some of the identified biomarkers were tentatively identified as the precursor compounds of the iridoid-derived pigments.",
        "keywords": [
            "Color",
            "Multivariate data analysis",
            "Potential metabolites",
            "Vaccinium bracteatum Thunb. leaves (VBTL)",
            "Wu mi"
        ],
        "authors": [
            {
                "name": "Mingcong Fan",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Yihui Fan",
                "org": "Department of Immunology, School of Medicine, Nantong University, 19 Qixiu Road, Nantong 226001, China."
            },
            {
                "name": "Zhiming Rao",
                "org": "School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Hui Zhang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Gangcheng Wu",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China."
            },
            {
                "name": "Li Wang",
                "org": "State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; National Engineering Research Center for Functional Food, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China. Electronic address: wl0519@163.com."
            }
        ],
        "venue": "Food chemistry",
        "year": 2019
    },
    "R1oj4l7z": {
        "id": "R1oj4l7z",
        "title": "Measuring Graph Proximity with Blink Model",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Hui Wan",
                "org": ""
            },
            {
                "name": "Mark N Wegman",
                "org": ""
            },
            {
                "name": "Luis A Lastras",
                "org": ""
            },
            {
                "name": "Ruchir Puri",
                "org": ""
            }
        ],
        "venue": "International Workshop on Mining and Learning with Graphs",
        "year": 2016
    },
    "GnyrqJ5e": {
        "id": "GnyrqJ5e",
        "title": "Efficient Proxy Blind Multi-signature Scheme",
        "abstract": "Digital proxy multi-signature scheme and blind signature are very suitable for electronic commerce and payment. Based on the Schnorr signature and Chaum blind signature scheme, this paper presents an efficient proxy blind multi-signature scheme, which satisfies the security properties of both the blind signature scheme and the proxy multi-signature scheme. This scheme has advantages such as the low computation load, high efficiency and security, and the length of signature does not increase when the new original signers join in. It is very important in an electronic cash and electronic vote system.",
        "keywords": [
            "proxy blind multi-signature",
            "blind signature",
            "proxy signature",
            "blindness",
            "proxy blind signature",
            "unlinkability",
            "bilinear pairings"
        ],
        "authors": [
            {
                "name": "HU Zhen-peng",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai "
            },
            {
                "name": "QIAN Hai-feng",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai "
            },
            {
                "name": "LI Zhi-bin",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2008
    },
    "qmGeKEs0": {
        "id": "qmGeKEs0",
        "title": "Efficient certificateless signcryption scheme",
        "abstract": "Certificateless cryptography not only overcomes the certificate management problems in the traditional public key cryptosystems,but also solves the key escrow problems in identity-based cryptosystems.Signcryption scheme combines the functionality of public key encryption and digital signature,which can realize the confidentiality and unforgeability of message simultaneously.This paper presents an efficient certificateless signcryption scheme,which only requires one pairing operation in the signcryption phase and three pairing operations in the unsigncryption phase.With comparison to the existing schemes,the efficiency of the scheme is better.For security requirements,this new scheme satisfies confidentiality,unforgeability and public verifiability.",
        "keywords": [
            "bilinear pairing",
            "public verifiability",
            "signcryption",
            "certificateless cryptography"
        ],
        "authors": [
            {
                "name": "WANG Xing",
                "org": "  Department of Computer Science,East China Normal University,Shanghai ,China"
            },
            {
                "name": "QIAN Haifeng",
                "org": "  Department of Computer Science,East China Normal University,Shanghai ,China"
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2011
    },
    "dyayzpyH": {
        "id": "dyayzpyH",
        "title": "Effects of trilostane and fipronil on the reproductive axis in an early life stage of the Japanese medaka ()",
        "abstract": "Given the critical role of the hypothalamic–pituitary–gonadal (HPG) axis, it is conceivable that perturbations at any point along this axis can potentially affect reproduction in fish and other vertebrates. We investigated the effects of a 3β-hydroxysteroid dehydrogenase (3β-HSD) inhibitor, trilostane (TRI), and a gamma-aminobutyric acid (GABA)-receptor antagonist, fipronil (FIP), on the HPG axis using an early life stage of the Japanese medaka. The newly hatched larvae were exposed to TRI (100, 300 and 1000 μg/L) and FIP (3, 10 and 30 μg/L), respectively, until 28 days post-hatching. Exposure to TRI decreased the body length in males, whereas FIP inhibited growth in both sexes. The induction of steroidogenesis-regulating genes (including -) in males exposed to TRI, accompanied by increased  and  transcription, indicating a compensatory response to the presumed 3β-HSD inhibition. These compensatory responses were not observed in TRI-treated females. Regarding FIP exposure, the GABA blocker resulted in the down-regulation of  and . A compensatory up-regulation of steroidogenesis-regulating genes partially explained the elevated transcripts of  genes in both males and females after FIP exposure. These results suggest that both the inhibition of 3β-HSD and the antagonism of GABA receptors are relevant modes of endocrine disruption that could impact the normal regulation of the HPG axis.",
        "keywords": [
            "Hypothalamic–pituitary–gonadal (HPG) axis",
            "3β-hydroxysteroid dehydrogenase (3β-HSD)",
            "Gamma-aminobutyric acid (GABA)",
            "Steroid synthesis",
            "Gender-specific effect"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Rong Jin",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zuhua Peng",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Qiwei Zhou",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou,People’s Republic of China"
            }
        ],
        "venue": "Ecotoxicology",
        "year": 2014
    },
    "o1TboPcV": {
        "id": "o1TboPcV",
        "title": "Security authentication protocol based on bilinear pairing (Chinese)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Huang Sushan",
                "org": ""
            },
            {
                "name": "Qian Haifeng",
                "org": ""
            },
            {
                "name": "Zhou Yuan",
                "org": ""
            }
        ],
        "venue": "Journal of East China Normal University",
        "year": 2010
    },
    "lzoOOZcR": {
        "id": "lzoOOZcR",
        "title": "Stochastic Preconditioning for Diagonally Dominant Matrices",
        "abstract": "This paper presents a new stochastic preconditioning approach for large sparse matrices. For the class of matrices that are rowwise and columnwise irreducibly diagonally dominant, we prove that an incomplete $\\rm{LDL^T}$ factorization in a symmetric case or an incomplete LDU factorization in an asymmetric case can be obtained from random walks and used as a preconditioner. It is argued that our factor matrices have better quality, i.e., better accuracy-size trade-offs, than preconditioners produced by existing incomplete factorization methods. Therefore a resulting preconditioned Krylov-subspace iterative solver requires less computation than traditional methods to solve a set of linear equations with the same error tolerance. The advantage increases for larger and denser matrices. These claims are verified by numerical tests, and we provide techniques that can potentially extend the theory to non-diagonally-dominant matrices.",
        "keywords": [
            "sparse matrices",
            "linear equations",
            "random walk",
            "krylov subspace",
            "preconditioning"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "qianhaifeng@us.ibm.com"
            },
            {
                "name": "Sachin S. Sapatnekar",
                "org": "sachin@ece.umn.edu"
            }
        ],
        "venue": "SIAM J. Scientific Computing",
        "year": 2008
    },
    "ZYn0Ql1b": {
        "id": "ZYn0Ql1b",
        "title": "Diclofop-methyl affects microbial rhizosphere community and induces systemic acquired resistance in rice.",
        "abstract": "Diclofop-methyl (DM), a widely used herbicide in food crops, may partly contaminate the soil surface of natural ecosystems in agricultural area and exert toxic effects at low dose to nontarget plants. Even though rhizosphere microorganisms strongly interact with root cells, little is known regarding their potential modulating effect on herbicide toxicity in plants. Here we exposed rice seedlings (Xiushui 63) to 100μg/L DM for 2 to 8days and studied the effects of DM on rice rhizosphere microorganisms, rice systemic acquired resistance (SAR) and rice-microorganisms interactions. The results of metagenomic 16S rDNA Illumina tags show that DM increases bacterial biomass and affects their community structure in the rice rhizosphere. After DM treatment, the relative abundance of the bacterium genera Massilia and Anderseniella increased the most relative to the control. In parallel, malate and oxalate exudation by rice roots increased, potentially acting as a carbon source for several rhizosphere bacteria. Transcriptomic analyses suggest that DM induced SAR in rice seedlings through the salicylic acid (but not the jasmonic acid) signal pathway. This response to DM stress conferred resistance to infection by a pathogenic bacterium, but was not influenced by the presence of bacteria in the rhizosphere since SAR transcripts did not change significantly in xenic and axenic plant roots exposed to DM. The present study provides new insights on the response of rice and its associated microorganisms to DM stress.",
        "keywords": [
            "Diclofop-methyl",
            "Organic acids",
            "Rhizosphere microorganisms",
            "Rice",
            "Systemic acquired resistance"
        ],
        "authors": [
            {
                "name": "Si Chen",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: cslock@126.com."
            },
            {
                "name": "Xingxing Li",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Laval University, Quebec, G1V OA6, Canada."
            },
            {
                "name": "Yujian Jin",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Jiahui Xu",
                "org": "Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Journal of environmental sciences (China)",
        "year": 2017
    },
    "stzB28yn": {
        "id": "stzB28yn",
        "title": "Phosphorylation and enzymatic hydrolysis with alcalase and papain effectively reduce allergic reactions to gliadins in normal mice.",
        "abstract": "Gliadins are major allergens responsible for wheat allergies. Food processing is an effective strategy to reduce the allergenicity of gluten. In the present study, we determined secondary and tertiary structure of gliadins treated with chemical, physical and enzymatic treatments through FTIR, surface hydrophobicity, intrinsic fluorescence spectrum and UV absorption spectrum. The results showed that the three treatments of phosphorylation, alcalase and papain hydrolysis significantly changed the conformational structures of gliadins, especially the secondary structure. Then, the potential allergenicity of the phosphorylated, alcalase and papain hydrolyzed gliadins were further characterized, and we observed a significant decrease in the allergenicity through the results of the index of spleen, serum total IgE, gliadin-specific IgE, histamine and serum cytokines concentrations. An elevation of Th17 cells, the absence of Treg cells, and an imbalance in Treg/Th17 are associated with allergy. Based on the expression levels of related cytokines and key transcription factors, we also confirmed that phosphorylation, alcalase and papain hydrolysis could effectively reduce the allergenicity of gliadins by improving the imbalance of both Th1/Th2 and Treg/Th17 in the spleens of sensitized mice. This study suggested that the changes of conformational structure contribute to gliadins hyposensitization, phosphorylation, alcalase and papain hydrolysis may be promising strategies for production of wheat products with low allergenicity.",
        "keywords": "",
        "authors": [
            {
                "name": "Lamei Xue",
                "org": ""
            },
            {
                "name": "Yan Li",
                "org": ""
            },
            {
                "name": "Tingting Li",
                "org": ""
            },
            {
                "name": "Haiou Pan",
                "org": ""
            },
            {
                "name": "Jinxin Liu",
                "org": ""
            },
            {
                "name": "Mingcong Fan",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Hui Zhang",
                "org": ""
            },
            {
                "name": "Hao Ying",
                "org": ""
            },
            {
                "name": "Li Wang",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2019
    },
    "cvrSozYo": {
        "id": "cvrSozYo",
        "title": "Chosen-ciphertext attack secure public key encryption with auxiliary inputs: CCA secure public key encryption with auxiliary inputs",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zhenfu cao",
                "org": ""
            },
            {
                "name": "zongyang zhang",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2012
    },
    "j0XvqO8W": {
        "id": "j0XvqO8W",
        "title": "Effects of 17α‑ethinylestradiol on caudal fin regeneration in zebrafish larvae.",
        "abstract": "The ability to restore tissue function and morphology after injury is a key advantage of many fish for a greater chance of survival. The tissue regeneration process is regulated by multiple pathways, and it can therefore be hypothesized that environmental contaminants targeting components of these signaling pathways, may disrupt the fish's capability to repair or regenerate. This could lead to higher mortality and eventually even to a decline in populations. In this study, the effects of 17α‑ethinylestradiol (EE2), a synthetic estrogen, were assessed on the regenerative capacity of larval zebrafish. Zebrafish aged 2 hour post fertilization (hpf) were exposed to 1, 10, or 100 ng/L EE2, and the caudal fins were amputated at 72 hpf. It was found that EE2 exposure significantly inhibited fin regeneration and changed locomotor behavior. The transcription levels for most of the genes involved in the signaling networks regulating the fin regeneration, such as axin2, fgfr1, bmp2b and igf2b, were down-regulated in the amputated fish in response to EE2 exposure, which was in contrast to their increased patterns in the vehicle-exposed control fish. Additionally, the mRNA levels of several immune-related genes, such as il-1β, il-6, il-10 and nf-κb2, were significantly decreased after EE2 exposure, accompanied by a lower density of neutrophils migrated into the wound site. In conclusion, the present study indicated for the first time that estrogenic endocrine disrupting chemicals (EEDCs) could inhibit the regenerative capacity of zebrafish, and this effect was speculated to be mediated through the alteration in regeneration-related signaling pathways and immune competence. This work expands our knowledge of the potential effects of EEDCs on injured aquatic organisms, and highlights the ecotoxicological significance of relationships between regenerative process and endocrine system. This study also implies the potential application of fin regeneration assay for assessing immunotoxicity in ecotoxicological risk assessment.",
        "keywords": [
            "Danio rerio",
            "Endocrine system",
            "Estrogenic endocrine disruption chemicals (EEDCs)",
            "Immune system",
            "Tissue repair and regeneration"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Linqi Gu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hana Tan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Pan Liu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Gan Gao",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Li Tian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Hui Chen",
                "org": "Department of Food Science and Technology, Ocean College, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: panxl@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "msT7R5Yr": {
        "id": "msT7R5Yr",
        "title": "Spatial-temporal pattern of sulfate-dependent anaerobic methane oxidation in an intertidal zone of the East China Sea.",
        "abstract": "Methane is a primary greenhouse gas which is responsible for global warming. The sulfate-dependent anaerobic methane oxidation (S-AOM) process catalyzed by ANaerobic MEthanotrophic (ANME) archaea and sulfate-reducing bacteria (SRB) is a vital link connecting the global carbon and sulfur cycles, and it is considered to be the overriding methane sink in marine ecosystem. However, there have been few studies regarding the role of S-AOM process and the distribution of ANME archaea in intertidal ecosystem. Intertidal zone is a buffer zone between sea and land, and plays an important role in global geochemical cycle. In this work, the abundance, potential methane oxidation rate and community structure of ANME archaea in the intertidal zone were studied by quantitative PCR, stable isotope tracing method and high-throughput sequencing. The results showed that the potential S-AOM activity ranged from 0 to 0.77 nmol CO g (dry sediment) day The copy number of 16S rRNA gene of ANME archaea reached 10 ∼ 10 copies g (dry sediment). The average contribution of S-AOM to total anaerobic methane oxidation was up to 34.5% while denitrifying anaerobic methane oxidation accounted for the rest, which implied that S-AOM process was an essential methane sink that cannot be overlooked in intertidal ecosystem. The simulated column experiments also indicated that ANME archaea were sensitive to oxygen and preferred anaerobic environmental conditions. This work will help us gain a better understanding of the global carbon-sulfur cycle and greenhouse gas emission reduction, and introduce a new perspective into the enrichment of ANME archaea. The sulfate-dependent anaerobic methane oxidation (S-AOM) process catalyzed by ANaerobic MEthanotrophic (ANME) archaea and sulfate-reducing bacteria (SRB) is a vital link connecting the global carbon and sulfur cycles. In this work, we conducted a research into the spatial-temporal pattern of S-AOM process and the distribution of ANME archaea in coastal sediments collected from the intertidal zone. The results of the work implied that S-AOM process was a methane sink that cannot be overlooked in the intertidal ecosystem. The work also indicated that ANME archaea were sensitive to oxygen and preferred anaerobic environmental conditions. This work will help us gain a better understanding of the global carbon-sulfur cycle and greenhouse gas emission reduction, and introduce a new perspective into the enrichment of ANME archaea.",
        "keywords": "",
        "authors": [
            {
                "name": "Jiaqi Wang",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Miaolian Hua",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Chaoyang Cai",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Jiajie Hu",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Junren Wang",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Hongrui Yang",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Fang Ma",
                "org": "State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China mafang@hit.edu.cn."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Ping Zheng",
                "org": "Department of Environmental Engineering, Zhejiang University, Hangzhou 310058, China."
            },
            {
                "name": "Baolan Hu",
                "org": "Zhejiang Province Key Laboratory for Water Pollution Control and Environmental Safety, Hangzhou 310058, China."
            }
        ],
        "venue": "Applied and environmental microbiology",
        "year": 2019
    },
    "MgxseqAX": {
        "id": "MgxseqAX",
        "title": "Interacting effect of diclofop-methyl on the rice rhizosphere microbiome and denitrification.",
        "abstract": "A better knowledge of the intertwined effects of herbicides on plant physiology and microbiome as well as nutrient biogeochemical cycles are needed for environmental management. Here we studied the influence of herbicide diclofop-methyl (DM) on the rice root microbiome and its relationship with N cycle. To do so, we exposed rice seedlings to 100 μg/L DM and studied rhizosphere microbiota using MiSeq-pyrosequencing, root exudation by GC-MS, and denitrification activity by N isotope-tracing and qRT-PCR. The richness and diversity of rhizosphere microorganisms, significantly increased after DM exposure combined with an increase in root exudation of amino acids, sugars, and fatty acids. Transcription of denitrification-related gene and denitrification rate increased significantly in the rice rhizosphere. Our results suggest that DM strongly influenced the root exudation of bacteria nutrients, which affected root microbiome community and potentially influenced N cycle in rice rhizosphere.",
        "keywords": [
            "Diclofop-methyl",
            "GC–MS",
            "MiSeq-pyrosequencing",
            "Rhizosphere microbial community",
            "Root exudates"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Si Chen",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yujian Jin",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: azwfu@zjut.edu.cn."
            }
        ],
        "venue": "Pesticide biochemistry and physiology",
        "year": 2018
    },
    "Lb3nKkil": {
        "id": "Lb3nKkil",
        "title": "CCA Secure Multi-recipient KEM from LPN.",
        "abstract": "We propose a novel multiple-recipient key-encapsulation mechanism (mKEM) scheme which takes multiple public keys as input and outputs a single key shared by corresponding recipients. We construct our scheme in the random oracle model based on low-noise LPN assumption which is a post-quantum problem. In the game simulation of security proof, a variant of Extended Knapsack LPN (which can be proved equivalent to standard LPN) is used to handle the decapsulation queries. The property of LPN problem provides randomness reuse property to shorten the length of the ciphertext compared with traditional way.",
        "keywords": "",
        "authors": [
            {
                "name": "Haitao Cheng",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Di Yan",
                "org": ""
            }
        ],
        "venue": "ICICS",
        "year": 2018
    },
    "MaYvm4SY": {
        "id": "MaYvm4SY",
        "title": "Enantioselective phytotoxicity of the herbicide imazethapyr on the response of the antioxidant system and starch metabolism in Arabidopsis thaliana.",
        "abstract": "The enantiomers of a chiral compound possess different biological activities, and one of the enantiomers usually shows a higher level of toxicity. Therefore, the exploration of the causative mechanism of enantioselective toxicity is regarded as one of primary goals of biological chemistry. Imazethapyr (IM) is an acetolactate synthase (ALS)-inhibiting chiral herbicide that has been widely used in recent years with racemate. We investigated the enantioselectivity between R- and S-IM to form reactive oxygen species (ROS) and to regulate antioxidant gene transcription and enzyme activity.Dramatic differences between the enantiomers were observed: the enantiomer of R-IM powerfully induced ROS formation, yet drastically reduced antioxidant gene transcription and enzyme activity, which led to an oxidative stress. The mechanism by which IM affects carbohydrate metabolism in chloroplasts has long remained a mystery. Here we report evidence that enantioselectivity also exists in starch metabolism. The enantiomer of R-IM resulted in the accumulation of glucose, maltose and sucrose in the cytoplasm or the chloroplast and disturbed carbohydrates utilization.The study suggests that R-IM more strongly retarded plant growth than S-IM not only by acting on ALS, but also by causing an imbalance in the antioxidant system and the disturbance of carbohydrate metabolism with enantioselective manner.",
        "keywords": [
            "carbohydrate metabolism",
            "stereoisomerism",
            "structure activity relationship",
            "gene transcription",
            "starch",
            "biological activity",
            "enzyme activity"
        ],
        "authors": [
            {
                "name": "HaiFeng Qian",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Tao Lu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "XiaoFeng Peng",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "Xiao Han",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "ZhengWei Fu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            },
            {
                "name": "WeiPing Liu",
                "org": "Zhejiang University of Technology(Zhejiang University of Technology),Hangzhou,China"
            }
        ],
        "venue": "PloS one",
        "year": 2011
    },
    "owAzBsxO": {
        "id": "owAzBsxO",
        "title": "Toxicity and enantiospecific differences of two β-blockers, propranolol and metoprolol, in the embryos and larvae of zebrafish (Danio rerio).",
        "abstract": "The risk presented by β-blockers on aquatic organisms remains uncertain, particularly given the enantiospecific differences in toxicity of chiral β-blockers. In this study, the toxicity of two β-blockers, propranolol and metoprolol, was determined. The 96-h LC50 of propranolol in the zebrafish larvae was 2.48 mg/L, whereas 50 mg/L metoprolol did not result in death. Both β-blockers decreased the heart rate and hatching rate and increased the mortality of the zebrafish embryos. Among these indicators, the heart rate was the most sensitive. However, the acute larval and embryo toxicity results displayed no enantioselectivity. Additionally, the transcriptional response of the genes encoding the β-adrenergic receptors and those involved in other physiological processes, including the antioxidant response, detoxification, and apoptosis, in zebrafish larvae exposed to the β-blockers was examined. Although the changes in gene transcription were fairly minor, significant enantioselectivity was observed for β-blockers, suggesting that the transcriptional response was more sensitive for the evaluation of enantiospecific toxicity. Based on these results, the pharmaceutical drugs were not expected to pose a risk to fish; however, this conclusion should not be considered final. These results also demonstrated that the enantiospecific toxicity of chiral β-blockers should be investigated when performing an ecological risk assessment.",
        "keywords": [
            "acute toxicity",
            "adrenergic receptor",
            "chiral",
            "embryonic developmental toxicity",
            "gene transcription"
        ],
        "authors": [
            {
                "name": "Liwei Sun",
                "org": "College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China."
            },
            {
                "name": "Lihua Xin",
                "org": ""
            },
            {
                "name": "Zuhua Peng",
                "org": ""
            },
            {
                "name": "Rong Jin",
                "org": ""
            },
            {
                "name": "Yuanxiang Jin",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Zhengwei Fu",
                "org": ""
            }
        ],
        "venue": "Environmental toxicology",
        "year": 2014
    },
    "NXQCrm4O": {
        "id": "NXQCrm4O",
        "title": "Interaction of chiral herbicides with soil microorganisms, algae and vascular plants",
        "abstract": "Abstract   Chiral herbicides are often used in agriculture as racemic mixtures, although studies have shown that the fate and toxicity of herbicide enantiomers to target and non-target plants can be enantioselective and that herbicide toxicity can be mediated by only one enantiomer. If one enantiomer is active against the target plant, the use of enantiomer-rich herbicide mixtures instead of racemic herbicides could decrease the amount of herbicide applied to a crop and the cost of herbicide application, as well as unintended toxic herbicide effects in the environment. Such a change in the management of herbicide applications requires in-depth knowledge and a critical analysis of the fate and effects of herbicide enantiomers in the environment. This review article first synthesizes the current state of knowledge on soil and plant biodegradation of herbicide enantiomers. Second, we discuss our understanding of the biochemical toxicity mechanisms associated with both enantiomers in target and non-target plants gained from state-of-the-art genomic, proteomic and metabolomic tools. Third, we present the emerging view on the “side effects” of herbicides in the root microbiome and their repercussions on target or non-target plant metabolism. Although our review of the literature indicates that the toxicity of herbicide enantiomers is highly variable depending on plant species and herbicides, we found general trends in the enantioselective toxic effects of different herbicides in vascular plants and algae. The present study will be helpful for pesticide risk assessments as well as for the management of applying enriched-enantiomer herbicides.",
        "keywords": "",
        "authors": [
            {
                "name": "Muhammad Asad Ullah Asad",
                "org": "College of Biotechnological and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec G1VOA6, Canada"
            },
            {
                "name": "Hao Song",
                "org": "College of Environment, Zhejiang University of technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Yujian Jin",
                "org": "College of Biotechnological and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnological and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China"
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of technology, Hangzhou 310032, PR China"
            }
        ],
        "venue": "Science of The Total Environment",
        "year": 2017
    },
    "ZO9dg5oq": {
        "id": "ZO9dg5oq",
        "title": "Nano-Sized Polystyrene at 1 mg/L Concentrations Does Not Show Strong Disturbance on the Freshwater Microbial Community.",
        "abstract": "In recent years, microplastics and nanoplastics have gained public attention, but their impacts on the freshwater microbial communities is rarely evaluated. In this study, the effects of 1 mg/L nano-sized polystyrene (nPS) and its modified forms (carboxyl-modified and amino-modified nPS) on the structures and functions of freshwater microbial community were determined. The nPS were found to slightly reduce the chlorophyll-a and increase the phycocyanin contents of freshwater microbial communities. Moreover, the richness of the microbial communities temporarily decreased during this process, while their diversity remained uninfluenced by treatment with nPS. Although the three tested nPS types were found to disturb the compositions of both the prokaryotic and eukaryotic communities to some degree, they did not affect the functions of freshwater bacterial communities significantly due to functional redundancy. Our study demonstrated that the ecotoxicities of the nPS itself were found to be lower than what is generally expected.",
        "keywords": [
            "Freshwater",
            "Microbial community",
            "Nano-sized polystyrene"
        ],
        "authors": [
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China."
            },
            {
                "name": "Meng Zheng",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China."
            },
            {
                "name": "Bingfeng Chen",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China."
            },
            {
                "name": "Yizhou Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China."
            },
            {
                "name": "Zhihan Yang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310014, China. hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2020
    },
    "OXabuwiL": {
        "id": "OXabuwiL",
        "title": "Insights into the transcriptional responses of a microbial community to silver nanoparticles in a freshwater microcosm.",
        "abstract": "Silver nanoparticles (AgNPs) are widely used because of their excellent antibacterial properties. They are, however, easily discharged into the water environment, causing potential adverse environmental effects. Meta-transcriptomic analyses are helpful to study the transcriptional response of prokaryotic and eukaryotic aquatic microorganisms to AgNPs. In the present study, microcosms were used to investigate the toxicity of AgNPs to a natural aquatic microbial community. It was found that a 7-day exposure to 10 μg L silver nanoparticles (AgNPs) dramatically affected the structure of the microbial community. Aquatic micro eukaryota (including eukaryotic algae, fungi, and zooplankton) and bacteria (i.e., heterotrophic bacteria and cyanobacteria) responded differently to the AgNPs stress. Meta-transcriptomic analyses demonstrated that eukaryota could use multiple cellular strategies to cope with AgNPs stress, such as enhancing nitrogen and sulfur metabolism, over-expressing genes related to translation, amino acids biosynthesis, and promoting bacterial-eukaryotic algae interactions. By contrast, bacteria were negatively affected by AgNPs with less signs of detoxification than in case of eukaryota; various pathways related to energy metabolism, DNA replication and genetic repair were seriously inhibited by AgNPs. As a result, eukaryotic algae (mainly Chlorophyta) dominated over cyanobacteria in the AgNPs treated microcosms over the 7-d exposure. The present study helps to understand the effects of AgNPs on aquatic microorganisms and provides insights into the contrasting AgNPs toxicity in eukaryota and bacteria.",
        "keywords": [
            "Cyanobacteria",
            "Eukaryote",
            "Green algae",
            "Meta-transcriptome",
            "Prokaryote",
            "Silver nanoparticles"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, G1VOA6, Canada."
            },
            {
                "name": "Xiangjie Pan",
                "org": "Zhejiang Fangyuan Test Group Co Ltd, Hangzhou, 310013, Zhejiang, PR China."
            },
            {
                "name": "W J G M Peijnenburg",
                "org": "Institute of Environmental Sciences (CML), Leiden University, 2300, RA, Leiden, the Netherlands; National Institute of Public Health and the Environment (RIVM), Center for Safety of Substances and Products, P.O. Box 1, 3720, BA, Bilthoven, the Netherlands."
            },
            {
                "name": "Zhigao Zhou",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China."
            },
            {
                "name": "Zhiqiang Cai",
                "org": "Laboratory of Applied Microbiology and Biotechnology, School of Pharmaceutical Engineering & Life Science, Changzhou University, Changzhou, Jiangsu, 213164, PR China. Electronic address: zhqcai@cczu.edu.cn."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2019
    },
    "qoTE7niQ": {
        "id": "qoTE7niQ",
        "title": "Efficient public key encryption with equality test in the standard model.",
        "abstract": "Abstract   Public key encryption with equality test (PKEET) is a special kind of public encryption scheme (PKE) that allows a tester to perform equality tests on ciphertexts generated by different public keys as well as the same public key. This feature enables us to apply PKEET to various scenarios in practice, such as efficient data management on encrypted databases and spam filtering in encrypted email systems. From these reasons, since Yang et al.  [1]  first proposed the concept of PKEET, there have been proposed many PKEET schemes to improve efficiency or to enhance functionalities. However, to the best of our knowledge, almost all existing schemes were presented under assuming the existence of random oracles, except for generic construction proposed by Lee et al. On the other hand, their generic approach for PKEET employs a 2-level hierarchical identity-based encryption and a strongly unforgeable one-time signature, which suffers from low efficiency.  In this paper, we propose an efficient PKEET scheme under a specific cryptographic assumption in the standard model. To this end, we first encrypt a message and its hash value in a parallel way by following the recently proposed strategy. Then, to prevent adaptive chosen ciphertext attacks (CCA2), we give a link between them by adapting the technique which was originally proposed for identity-based encryption and previously exploited to design efficient CCA2-secure PKE schemes. We show that our proposed construction satisfies formal security requirements for PKEET under the decisional bilinear Diffie–Hellman (DBDH) assumption in the standard model. As a result, we obtain a new PKEET scheme which has shorter ciphertext and trapdoor sizes, and improves computational costs for encryption, decryption, and test algorithms, by about 60%, 77%, and 66%, respectively, compared to a PKEET instantiation obtained by the prior generic framework.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai Zhang",
                "org": "Department of Information Security, College of Computer Science and Technology, Shanghai University of Electric Power, Shanghai, China"
            },
            {
                "name": "Jie Chen",
                "org": "State Key Laboratory of Integrated Services Networks, Xidian University, Xi'an, China"
            },
            {
                "name": "Hyung Tae Lee",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Huaxiong Wang",
                "org": "Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore"
            }
        ],
        "venue": "Theor. Comput. Sci.",
        "year": 2019
    },
    "9xS407Mb": {
        "id": "9xS407Mb",
        "title": "Signcryption KEM/tag‐KEM, revisited",
        "abstract": "We revisit the problem of basing signcryption (SC) (tag) key encapsulation mechanism\n         (KEM) on standard assumptions and standard model and present direct constructions\n         of SC‐KEM/tag‐KEM, which \n         \n         ",
        "keywords": [
            "signcryption",
            "key encapsulation mechanism",
            "tag",
            "standard model",
            "standard assumption"
        ],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": "east china normal university"
            },
            {
                "name": "Haifeng Qian",
                "org": "east china normal university"
            },
            {
                "name": "Yu Yu",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "Jian Weng",
                "org": "jinan university"
            },
            {
                "name": "Yuan Zhou",
                "org": "east china normal university"
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2015
    },
    "lUEQBxJO": {
        "id": "lUEQBxJO",
        "title": "Effects of imazethapyr spraying on plant growth and leaf surface microbial communities in Arabidopsis thaliana",
        "abstract": "Imazethapyr (IM) is an acetolactate synthase (ALS)-inhibiting herbicide that has been widely used in recent years. However, IM spraying can lead to the accumulation of herbicide residues in leaves. Here, we determined the effects of IM spraying on the plant growth and leaf surface microbial communities of Arabidopsis thaliana after 7 and 14 days of exposure. The results suggested that IM spraying inhibited plant growth. Fresh weight decreased to 48% and 26% of the control value after 7 and 14 days, respectively, of 0.035 kg/ha IM exposure. In addition, anthocyanin content increased 9.2-fold and 37.2-fold relative to the control content after 7 and 14 days of treatment, respectively. Furthermore, IM spraying destroyed the cell structures of the leaves, as evidenced by increases in the number of starch granules and the stomatal closure rate. Reductions in photosynthetic efficiency and antioxidant enzyme activity were observed after IM spraying, especially after 14 days of exposure. The diversity and evenness of the leaf microbiota were not affected by IM treatment, but the composition of community structure at the genus level was altered by IM spraying. Imazethapyr application increased the abundance of Pseudomonas, a genus that includes species pathogenic to plants and humans, indicating that IM potentially increased the abundance of pathogenic bacteria on leaves. Our findings increase our understanding of the relationships between herbicide application and the microbial community structures on plant leaves, and they provide a new perspective for studying the ecological safety of herbicide usage.",
        "keywords": [
            "16S rRNA gene",
            "Arabidopsis thaliana",
            "Herbicides",
            "Imidazolinones",
            "Phyllosphere microorganisms"
        ],
        "authors": [
            {
                "name": "Wanyue Liu",
                "org": "State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Yan Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China."
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Journal of Environmental Sciences-china",
        "year": 2019
    },
    "J5s5S2Bb": {
        "id": "J5s5S2Bb",
        "title": "Thwarting location privacy protection in location-based social discovery services.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Minhui Xue",
                "org": ""
            },
            {
                "name": "Yong Liu",
                "org": ""
            },
            {
                "name": "Keith W. Ross",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Security and Communication Networks",
        "year": 2016
    },
    "U6AskwAF": {
        "id": "U6AskwAF",
        "title": "Design methodology for the IBM POWER7 microprocessor",
        "abstract": "The IBM POWER7® microprocessor, which is the next-generation IBM POWER® processor, leverages IBM's 45-nm silicon-on-insulator (SOI) process with embedded dynamic random access memory to achieve industry-leading performance. To deliver this complex 567-mm2 die, the IBM design team made significant innovations in chip design methodology. This paper describes the most critical methodology innovations specific to POWER7 design, which were in modularity, timing closure, and design efficiency.",
        "keywords": [
            "embedded dynamic random access",
            "chip design methodology",
            "ibm power7",
            "ibm power7 microprocessor",
            "ibm design team",
            "power7 design",
            "leverages ibm",
            "design efficiency",
            "critical methodology innovation",
            "45-nm silicon-on-insulator",
            "next-generation ibm power",
            "design methodology"
        ],
        "authors": [
            {
                "name": "Joshua Friedrich",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Ruchir Puri",
                "org": "IBM Research Division, Thomas J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Uwe Brandt",
                "org": "IBM Systems and Technology Group, Boeblingen, Germany"
            },
            {
                "name": "Markus Buehler",
                "org": "IBM Systems and Technology Group, Boeblingen, Germany"
            },
            {
                "name": "Jack DiLullo",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Jeremy Hopkins",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Mozammel Hossain",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Michael Kazda",
                "org": "IBM Systems and Technology Group, East Fishkill, NY"
            },
            {
                "name": "Joachim Keinert",
                "org": "IBM Systems and Technology Group, Boeblingen, Germany"
            },
            {
                "name": "Zahi M. Kurzum",
                "org": "IBM Systems and Technology Group, Hopewell Junction, NY"
            },
            {
                "name": "Douglass Lamb",
                "org": "IBM Systems and Technology Group, Research Triangle Park, NC"
            },
            {
                "name": "Alice Lee",
                "org": "IBM Systems and Technology Group, Lexington, MA"
            },
            {
                "name": "Frank Musante",
                "org": "IBM Systems and Technology Group, Hopewell Junction, NY"
            },
            {
                "name": "Jens Noack",
                "org": "IBM Systems and Technology Group, Boeblingen, Germany"
            },
            {
                "name": "Peter J. Osler",
                "org": "IBM Systems and Technology Group, Essex Junction, VT"
            },
            {
                "name": "Stephen Posluszny",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Haifeng Qian",
                "org": "IBM Research Division, Thomas J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Shyam Ramji",
                "org": "IBM Systems and Technology Group, Hopewell Junction, NY"
            },
            {
                "name": "Vasant Rao",
                "org": "IBM Systems and Technology Group, Hopewell Junction, NY"
            },
            {
                "name": "Lakshmi N. Reddy",
                "org": "IBM Systems and Technology Group, Yorktown Heights, NY"
            },
            {
                "name": "Haoxing Ren",
                "org": "IBM Research Division, Thomas J. Watson Research Center, Yorktown Heights, NY"
            },
            {
                "name": "Thomas Rosser",
                "org": "IBM Systems and Technology Group, Austin, TX"
            },
            {
                "name": "Benjamin R. Russell",
                "org": "IBM Systems and Technology Group, Waltham, MA"
            },
            {
                "name": "Cliff Sze",
                "org": "IBM Research Division, Austin Research Laboratory, Austin, TX"
            },
            {
                "name": "Gustavo Téllez",
                "org": "IBM Systems and Technology Group, Essex Junction, VT"
            }
        ],
        "venue": "IBM Journal of Research and Development",
        "year": 2011
    },
    "gnKK33P3": {
        "id": "gnKK33P3",
        "title": "Simpler CCA Secure PKE from LPN Problem Without Double-Trapdoor.",
        "abstract": "The first CCA secure public key encryption (PKE) on the learning parity with noise (LPN) assumption was invented by Dottling et al. (ASIACRYPT 2012). At PKC 2014, Kiltz et al. gave a simpler and more efficient construction, where a double-trapdoor technique was introduced to handle the decryption queries in game simulation. Different from the technique, we build in the standard model the CCA secure PKE on a variant of Extended Knapsack LPN problem (which is provably equivalent to the standard LPN problem). We abstract out an ephemeral key from the LPN assumption, which can then be used to encrypt the underlying plaintext when equipped with several typical classes of cryptographic primitives. Thanks to these techniques, the decryption queries can be correctly answered (yet without relying on a double-trapdoor mechanism) during security reduction from LPN. The resulting simple proposal appears more modular and efficient.",
        "keywords": "",
        "authors": [
            {
                "name": "Haitao Cheng",
                "org": ""
            },
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Di Yan",
                "org": ""
            }
        ],
        "venue": "ICICS",
        "year": 2018
    },
    "KrYVs0lq": {
        "id": "KrYVs0lq",
        "title": "The Effects of Low Concentrations of Silver Nanoparticles on Wheat Growth, Seed Quality, and Soil Microbial Communities",
        "abstract": "The growing demand for and production of commercial silver nanoparticles (AgNPs) inevitably increases the risk for their environmental release and soil accumulation, which could have deleterious effects on plant growth and soil microorganism communities. However, to date, little is known about how AgNPs impact plant growth, seed quality, and soil microbial communities. We therefore evaluated wheat growth and seed quality after exposure to low concentration of AgNPs while characterizing the composition of the associated soil microbial community by high-throughput sequencing of 16S rRNA genes. Our results showed that low concentration of AgNPs (1 mg/kg in fresh soil) neither inhibited wheat seedling growth nor changed the amino acid content in wheat seeds. Interestingly, the soil microorganisms in the wheat-planted group had more diversity and richness than those in the bulk-soil group. The structure of the bacterial community was affected by AgNP exposure, most significantly during the transition from the seedling to the vegetative stage of the wheat, but recovered to normal level after 49 days of treatment. In conclusion, the results from this study highlight that the environmental risks associated with low concentration of AgNPs, which have clear bioeffects on soil microorganisms, warrant further investigation.",
        "keywords": [
            "AgNPs",
            " Soil microorganism",
            " Wheat",
            " Seeds"
        ],
        "authors": [
            {
                "name": "Guangfu Liu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Meng Zhang",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Yujian Jin",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Xiaoji Fan",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Jiahui Xu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Youchao Zhu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Zhengwei Fu",
                "org": "Zhejiang University of Technology"
            },
            {
                "name": "Xiangliang Pan",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Water Air and Soil Pollution",
        "year": 2017
    },
    "bik4PGVW": {
        "id": "bik4PGVW",
        "title": "The fungicide azoxystrobin perturbs the gut microbiota community and enriches antibiotic resistance genes in Enchytraeus crypticus.",
        "abstract": "The use of pesticides to ensure global food security is the most important pest control strategy in modern agriculture but causes extensive soil pollution. This pollution involves potential risks to human health and ecosystems. In addition to soil animal growth, the adverse impact of pesticides on the gut microbiomes of nontarget soil fauna remains largely unknown. Here, the effect of the fungicide azoxystrobin (AZ) on soil and the gut microbiota of soil animals (Enchytraeus crypticus) was studied. The tested concentrations of AZ altered the bacterial community in the soil and E. crypticus gut and were slightly toxic with respect to E. crypticus adult mortality and reproduction. The most abundant bacterial phylum, Proteobacteria, significantly increased in response to the 2 and 5 mg/kg AZ treatments, which implied a disordered unhealthy gut bacterial community. Furthermore, bacterial community analysis between the soil and gut showed that the main effect of AZ on the gut microbiota was directly through AZ, not soil microbiota. In addition, AZ exposure significantly enhanced the number and total abundance of antibiotic resistance genes (ARGs) in the E. crypticus gut; these genes may enter the soil food web to affect higher trophic levels and cause a more serious ecological risk. Our study reported the effect of pesticides on the gut of soil animals and on the enrichment of ARGs as global emerging contaminants, revealing unknown potential impacts of fungicides on ecosystem services and sustainable food production.",
        "keywords": [
            "Antibiotic resistance genes",
            "Azoxystrobin",
            "Enchytraeus",
            "Fungicide",
            "Gut microbiota"
        ],
        "authors": [
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Dong Zhu",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China."
            },
            {
                "name": "Jing Ding",
                "org": "University of the Chinese Academy of Sciences, Beijing 100049, PR China; State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China."
            },
            {
                "name": "Fei Zheng",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China."
            },
            {
                "name": "Shuyidan Zhou",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Yong-Guan Zhu",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China; State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environment international",
        "year": 2019
    },
    "JavsZ6Nm": {
        "id": "JavsZ6Nm",
        "title": "Intercalibration of GOES Imager visible channels over the Sonoran Desert",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "fangfang yu",
                "org": ""
            },
            {
                "name": "xiangqian wu",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "michael grotenhuis",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": "m systems"
            }
        ],
        "venue": "Journal of Geophysical Research",
        "year": 2014
    },
    "vjDlKV4c": {
        "id": "vjDlKV4c",
        "title": "Temperature-aware placement for SOCs",
        "abstract": "Dramatic rises in the power consumption and integration density of contemporary systems-on-chip (SoCs) have led to the need for careful attention to chip-level thermal integrity. High temperatures or uneven temperature distributions may result not only in reliability issues, but also timing failures, due to the temperature-dependent nature of chip time-to-failure and delay, respectively. To resolve these issues, high-quality, accurate thermal modeling and analysis, and thermally oriented placement optimizations, are essential prior to tapeout. This paper first presents an overview of thermal modeling and simulation methods, such as finite-difference time domain, finite element, model reduction, random walk, and Green-function based algorithms, that are appropriate for use in placement algorithms. Next, two-dimensional and three-dimensional thermal-aware placement algorithms such as matrix-synthesis, simulated …",
        "keywords": "",
        "authors": [
            {
                "name": "Jeng-Liang Tsai",
                "org": ""
            },
            {
                "name": "CC-P Chen",
                "org": ""
            },
            {
                "name": "Guoqiang Chen",
                "org": ""
            },
            {
                "name": "Brent Goplen",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yong Zhan",
                "org": ""
            },
            {
                "name": "Sung-Mo Kang",
                "org": ""
            },
            {
                "name": "Martin DF Wong",
                "org": ""
            },
            {
                "name": "Sachin S Sapatnekar",
                "org": ""
            }
        ],
        "venue": "Proceedings of the IEEE",
        "year": 2006
    },
    "8ENiRjAh": {
        "id": "8ENiRjAh",
        "title": "Staling of cake prepared from rice flour and sticky rice flour",
        "abstract": "MiGao, prepared from rice flour and sticky rice flour, is a kind of steam cooked Chinese cake. Staling of MiGao resulted in loss in texture and eating quality. Moisture content, water activity, texture, differential scanning calorimetry thermograms and sensory quality of MiGao, were monitored and were found to be significantly affected by cake staling when stored at room temperature for up to 5 days. The moisture content decreased after 2 days of storage and during the following days the crumb moisture content remained practically unchanged. Firmness was developed mainly during the first day of storage, remained at a similar level from day 2 to 3 and increased slightly after the third day of storage. A decrease in sensory quality and acceptability of the MiGao was observed during storage. Differential scanning calorimetry was used to follow changes of starch retrogradation in MiGao crumb. Amylopectin recrystallisation in MiGao continued to increase during storage.",
        "keywords": [
            "cake",
            "staling",
            "differential scanning calorimetry",
            "texture",
            "room temperature",
            "water activity",
            "moisture content"
        ],
        "authors": [
            {
                "name": "Ying Ji",
                "org": "Key Laboratory of Food Science and Safety, Ministry of Education, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Kexue Zhu",
                "org": "Key Laboratory of Food Science and Safety, Ministry of Education, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Key Laboratory of Food Science and Safety, Ministry of Education, Southern Yangtze University, 170 Huihe Road, Wuxi 214036, Jiangsu Province, PR China"
            },
            {
                "name": "Huiming Zhou",
                "org": ""
            }
        ],
        "venue": "Food Chemistry",
        "year": 2007
    },
    "IEZ0AMoJ": {
        "id": "IEZ0AMoJ",
        "title": "Evaluation of the toxic response induced by azoxystrobin in the non-target green alga Chlorella pyrenoidosa.",
        "abstract": "The top-selling strobilurin, azoxystrobin (AZ), is a broad-spectrum fungicide that protects against many kinds of pathogenic fungi by preventing their ATP production. The extensive use of AZ can have negative consequences on non-target species and its effects and toxic mechanisms on algae are still poorly understood. In this work, Chlorella pyrenoidosa that had been grown in BG-11 medium was exposed to AZ (0.5-10 mg L-1) for 10 d. The physiological and molecular responses of the algae to AZ treatment, including photosynthetic efficiency, lipid peroxidation level, antioxidant enzyme activities, as well as transcriptome-based analysis of gene expression, were examined to investigate the potential toxic mechanism. Results shows that the photosynthetic pigment (per cell) increased slightly after AZ treatments, indicating that the photosystem of C. pyrenoidosa may have been strengthened. Glutathione and ascorbate contents were increased, and antioxidant enzyme activities were induced to relieve oxidative damage (e.g., from lipid peroxidation) in algae after AZ treatment. Transcriptome-based analysis of gene expression combined with physiological verification suggested that the 5 mg L-1 AZ treatment did not inhibit ATP generation in C. pyrenoidosa, but did significantly alter amino acid metabolism, especially in aspartate- and glutamine-related reactions. Moreover, perturbation of ascorbate synthesis, fat acid metabolism, and RNA translation was also observed, suggesting that AZ inhibits algal cell growth through multiple pathways. The identification of AZ-responsive genes in the eukaryotic alga C. pyrenoidosa provides new insight into AZ stress responses in a non-target organism.",
        "keywords": [
            "Amino acid metabolism",
            "Azoxystrobin",
            "Chlorella pyrenoidosa",
            "Transcriptome"
        ],
        "authors": [
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Youchao Zhu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Jiahui Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Mingjing Ke",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Meng Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Chengxia Tan",
                "org": "College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2017
    },
    "5w9hbRU5": {
        "id": "5w9hbRU5",
        "title": "Extrusion followed by ultrasound as a chemical-free pretreatment method to enhance enzymatic hydrolysis of rice hull for fermentable sugars production",
        "abstract": "Abstract   The rice hull is an abundant and renewable biomass resource, which contains rich carbohydrates and can be used as an alternative energy source. In order to exploit and utilize the biomass energy in rice hull, extrusion and ultrasound technologies were used to pretreat the rice hull. Response surface method (RSM) was used to optimize the extrusion conditions, and the optimum extrusion condition were obtained as the follows: material diameter, 60 mesh; material moisture, 29 %; extrusion temperature, 143 °C; screw speed, 350 rpm. Under the conditions, the expansion degree of rice hull was 2.16. After extrusion, the rice hull was subjected to ultrasound pretreatment for 1.5 h at 40 KHz/500 W. After this above, cellulase, β-glucosidase, and hemicellulose were used to hydrolyze the rice hull. And 77.50 % of conversion of total cellulose and hemicellulose was obtained. The yield for reducing sugars, glucose, and xylose was 381.59, 291.59, and 88.87 mg/g rice hull, respectively.",
        "keywords": "",
        "authors": [
            {
                "name": "Youwei Zhang",
                "org": "School of Food Science and Technology, Jiangsu Food and Pharmaceutical Science College, 4 Meicheng Road, Huai’an 223003, China"
            },
            {
                "name": "Tingting Li",
                "org": "Department of Food Science and Technology, College of Light Industry and Food Engineer, Nanjing Forestry University, Nanjing 210037, China"
            },
            {
                "name": "Yingbin Shen",
                "org": "Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China"
            },
            {
                "name": "Li Wang",
                "org": "School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Hui Zhang",
                "org": "School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            },
            {
                "name": "Xiguang Qi",
                "org": "School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China"
            }
        ],
        "venue": "Industrial Crops and Products",
        "year": 2020
    },
    "2wwtZbQn": {
        "id": "2wwtZbQn",
        "title": "Notes on a group-oriented setting's multisigncryption scheme with threshold designcryption",
        "abstract": "Zhang et al. proposed recently a group-oriented multisigncryption scheme with threshold designcryption and affirmed that their scheme is secure under standard complexity assumptions. However, the note elaborates concrete attacks on its indistinguishability and unforgeability under their security models. We also provide the impossibility result of public ciphertext authenticity for the scheme.",
        "keywords": [],
        "authors": [
            {
                "name": "Xiangxue Li",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Yuan Zhou",
                "org": ""
            }
        ],
        "venue": "Inf. Sci.",
        "year": 2014
    },
    "ya7z4UcC": {
        "id": "ya7z4UcC",
        "title": "Carbon dioxide enrichment and brassinosteroid pretreatment alleviate chlorpyrifos phytotoxicity under suboptimal light and temperature conditions in tomato",
        "abstract": "",
        "keywords": [
            "stress",
            "pesticide"
        ],
        "authors": [
            {
                "name": "liwei sun",
                "org": ""
            },
            {
                "name": "lin ren",
                "org": ""
            },
            {
                "name": "tao peng",
                "org": ""
            },
            {
                "name": "lihua xin",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            }
        ],
        "venue": "Scientia Horticulturae",
        "year": 2015
    },
    "MOXrgBRt": {
        "id": "MOXrgBRt",
        "title": "Rhizosphere microbiome assemble and its impact on plant growth.",
        "abstract": "Microorganisms colonizing the plant rhizosphere provide a number of beneficial functions for their host. Although an increasing number of investigations clarified the great functional capabilities of rhizosphere microbial communities, the understanding of the precise mechanisms underlying the impact of rhizosphere microbiome assemblies is still limited. Also, not much is known about the various beneficial functions of the rhizosphere microbiome. In this review, we summarize the current knowledge of biotic and abiotic factors that shape the rhizosphere microbiome, as well as the rhizosphere microbiome traits that are beneficial to plants growth and disease-resistance. We give particular emphasis on the impact of plant root metabolites on rhizosphere microbiome assemblies and on how the microbiome contributes to plant growth, yield, and disease-resistance. Finally, we introduce a new perspective and a novel method showing how a synthetic microbial community construction provides an effective approach to unravel the plant-microbes and microbes-microbes interplays. Keywords: Plant, Rhizosphere microbiome, Growth-promotion, Disease-resistance, Synthetic microbial community.",
        "keywords": "",
        "authors": [
            {
                "name": "Qian Qu",
                "org": ""
            },
            {
                "name": "Zhenyan Zhang",
                "org": ""
            },
            {
                "name": "W J G M Peijnenburg",
                "org": ""
            },
            {
                "name": "Wanyue Liu",
                "org": ""
            },
            {
                "name": "Tao Lu",
                "org": ""
            },
            {
                "name": "Baolan Hu",
                "org": ""
            },
            {
                "name": "Jian-Meng Chen",
                "org": ""
            },
            {
                "name": "Jun Chen",
                "org": ""
            },
            {
                "name": "Zhifen Lin",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2020
    },
    "MDFjSzCn": {
        "id": "MDFjSzCn",
        "title": "Stabilizing interaction of exopolymers with nano-Se and impact on mercury immobilization in soil and groundwater",
        "abstract": "Remediation of metal-contaminated soils and waters using nanoparticles is highly limited by their strong tendency to aggregate in soil solution and natural water. In order to enhance the remediation of Hg0-contaminated soil solution and groundwater by Se nanoparticles (SeNPs), the effects of extracellular polymeric substances (EPS) on the stability of SeNPs and Hg0 removal were investigated. EPS from the selenite-reducing bacterium Citrobacter freundii Y9 were found to make SeNPs more negatively charged by strong adsorption, which significantly enhanced the stability of SeNPs. The protein, carboxylate, polysaccharide and lipid components of the EPS were involved in the adsorption to SeNPs. Fluorescence quenching titration measurements implied that the binding of proteinaceous substances in the EPS to SeNPs was static quenching. EPS can therefore enhance the remediation efficiency of SeNPs for soil solution and groundwater contaminated with Hg0. This study highlights that bacterial EPS can be used as an effective natural dispersant for SeNPs, therefore improving the efficiency of mercury immobilization in contaminated waters.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaonan Wang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences,Urumqi 830011,China"
            },
            {
                "name": "Wenjuan Song",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences,Urumqi 830011,China"
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Haifeng Qian",
                "org": ""
            },
            {
                "name": "Daoyong Zhang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences,Urumqi 830011,China"
            },
            {
                "name": "Daoyong Zhang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences,Urumqi 830011,China"
            },
            {
                "name": "Xiangliang Pan",
                "org": ""
            },
            {
                "name": "Xiangliang Pan",
                "org": ""
            },
            {
                "name": "Geoffrey M. Gadd",
                "org": "Geomicrobiology Group, School of Life Sciences, University of Dundee,Dundee DD15EH,UK"
            }
        ],
        "venue": "Environmental science. Nano",
        "year": 2018
    },
    "Nb9Ln1rL": {
        "id": "Nb9Ln1rL",
        "title": "Purification and Identification of Antifreeze Protein From Cold-Acclimated Oat (.) and the Cryoprotective Activities in Ice Cream",
        "abstract": "Antifreeze proteins (AFPs) were extracted from cold-acclimated oat by vacuum infiltration–centrifugation. Ammonium precipitation, ion exchange, and size-exclusion chromatography were used successively to purify the oat AFPs (AsAFPs), and the proteins were identified using matrix-assisted laser desorption/ionization time of flight tandem mass spectrometry. The results showed that an ammonium-sulfate saturation of 50–100 % was optimal for supernatant precipitation. After purification, AsAFP was found to have achieved an electrophoretic purity and its thermal-hysteresis activity was measured at 1.24 °C (15 mg ml). The mass fingerprinting and sequencing results indicated the homology of AsAFP and endochitinase. Recrystallization and melting resistance of ice cream were improved by AsAFP (0.1 %). Moreover, the addition of AsAFP (0.1 %) in ice cream increased the glass transition temperature (Tg) from −29.14 to −27.74 °C.",
        "keywords": [
            "Oat (",
            "Avena sativa L",
            ".)",
            "Antifreeze protein",
            "Purification",
            "Identification",
            "Cryoprotective activities",
            "Glass transition temperature",
            "Ice recrystallization",
            "Melting resistance"
        ],
        "authors": [
            {
                "name": "Yanjie Zhang",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Hui Zhang",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Xiangli Ding",
                "org": "College of Tourism and Culinary Science,Yangzhou University,Yangzhou,China"
            },
            {
                "name": "Lilin Cheng",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Li Wang",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Haifeng Qian",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Xiguang Qi",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            },
            {
                "name": "Chaoyang Song",
                "org": "State Key laboratory of Food Science and Technology, School of Food Science and Technology,Jiangnan University,Wuxi,China"
            }
        ],
        "venue": "Food and Bioprocess Technology",
        "year": 2016
    },
    "c6urVKBQ": {
        "id": "c6urVKBQ",
        "title": "Responses of unicellular alga Chlorella pyrenoidosa to allelochemical linoleic acid.",
        "abstract": "Linoleic acid (LA), is the product of secondary metabolism secreted from Microcystis aeruginosa, and it exhibits allelopathic activity against eukaryotic algae. However, information about on the mechanisms associated with the inhibition of algal activity by LA is limited. In this study, Chlorella pyrenoidosa was treated with LA (20-120 μg L) for 4 days, and its growth inhibition and physiological responses were examined for potential toxic mechanisms. The photosynthetic efficiency of C. pyrenoidosa was inhibited by LA treatments, and the F/F parameter decreased significantly compared to that of controls; however, the photosynthetic pigment content did not change significantly. Peroxidase activity was enhanced, relieving oxidative damage in algae after LA treatments. However, superoxide dismutase and catalase were suppressed, ultimately leading to the aggravation of lipid peroxidation. Transcriptome-based gene expression analysis revealed that the 120 μg L LA treatment significantly inhibited the transcription of genes related to photosynthesis, carbon metabolism, and amino acid metabolism in C. pyrenoidosa, suggesting that these genes might be key LA targets in C. pyrenoidosa. Moreover, the expression of genes involved in vitamin, lipid, nitrogen cycling, terpenoid, and ascorbate metabolism was also affected, suggesting that LA inhibits algal cell growth through multiple pathways. The identification of LA-responsive genes in C. pyrenoidosa provides new insight into LA stress responses in eukaryotic algae.",
        "keywords": [
            "Algal toxicity",
            "Allelochemical",
            "Chlorella pyrenoidosa",
            "Linoleic acid",
            "Transcriptome"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China; College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China. Electronic address: hfqian@zjut.edu.cn."
            },
            {
                "name": "Jiahui Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Qian Qu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhaopeng Yang",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "6w3Irwh6": {
        "id": "6w3Irwh6",
        "title": "Public key encryption with equality test via hash proof system.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Ming Zeng",
                "org": "Department of Computer Science & Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Jie Chen",
                "org": "Department of Computer Science & Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Kai Zhang",
                "org": "Department of Information Security, College of Computer Science and Technology, Shanghai University of Electric Power, Shanghai, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Dept of Computer Science and Technology, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "Theor. Comput. Sci.",
        "year": 2019
    },
    "MpDsYHJA": {
        "id": "MpDsYHJA",
        "title": "Hybrid proxy multisignature: A new type multi-party signature",
        "abstract": "In this paper, we introduce a new type of multi-party signature: hybrid proxy multisignature (HPM). An HPM is collaboratively generated by some signers themselves and some proxy signers on behalf of their original signers. We describe the syntax of general HPM schemes and formalize a notion of security for them. We also construct a concrete HPM scheme and prove its security in the Random Oracle Model, assuming the Co-Diffie-Hellman problem in the underlying groups equipped with a pairing is hard. The size of an HPM in our scheme is independent of the number of the actual signers. Further, the scheme has accountability, that is the signers of an HPM can be identified. Comparing with other types of multi-party signatures such as multisignature, proxy multisignature and multiproxy multisignature, HPM has more flexibility.",
        "keywords": [
            "actual signer",
            "new type multi-party signature",
            "general hpm scheme",
            "hybrid proxy multisignature",
            "co-diffie-hellman problem",
            "proxy signer",
            "multiproxy multisignature",
            "proxy multisignature",
            "multi-party signature",
            "concrete hpm scheme",
            "random oracle model",
            "it security",
            "digital signature",
            "diffie hellman"
        ],
        "authors": [
            {
                "name": "Zecheng Wang",
                "org": "Institute of Theoretical Computing, East China Normal University, Shanghai 200062, PR China and Department of Computer Science and Technology, Anhui University of Finance and Economics, Bengbu 233 ..."
            },
            {
                "name": "Haifeng Qian",
                "org": "Institute of Theoretical Computing, East China Normal University, Shanghai 200062, PR China"
            },
            {
                "name": "Zhibin Li",
                "org": "Institute of Theoretical Computing, East China Normal University, Shanghai 200062, PR China"
            }
        ],
        "venue": "Inf. Sci.",
        "year": 2007
    },
    "1zCGMDtK": {
        "id": "1zCGMDtK",
        "title": "P3GQ: A practical privacy-preserving generic location-based services query scheme.",
        "abstract": "Abstract   The Location-Based Services (LBS) enables people to find location places according to their interests. As the size of LBS dataset surprisingly increases, the LBS providers inevitably outsource their LBS dataset to a cloud server, but needs to encrypt it at first for preventing sensitive information leakage. However, designing a scheme that supports generic LBS query over encrypted data is still a challenging problem. Motivated by this, we present a practical privacy-preserving generic LBS query scheme (     P    3    GQ   ), which achieves both data privacy and query privacy. In the scheme, a LBS provider outsources its dataset to a cloud server and relies on it to process LBS queries, but leaks no confidential information about both the dataset and queries to the cloud server. More specifically, we introduce a new tool called    CircleTest   : to test whether a point is inside of a given circular area or not, while keeps them secret. Hence, we obtain the      P    3    GQ    scheme to support for generic LBS query while achieving privacy-preserving based on the    CircleTest    building block and an encrypted inverted index technique. We analyze the privacy requirements of our scheme, and additionally conduct an experiment on both the building block    CircleTest    and the      P    3    GQ    scheme to show their practical performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Ming Zeng",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Kai Zhang",
                "org": "Department of Information Security, Shanghai University of Electric Power, Shanghai, China"
            },
            {
                "name": "Jie Chen",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "Department of Computer Science and Technology, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "Pervasive and Mobile Computing",
        "year": 2018
    },
    "Pe5vPxbE": {
        "id": "Pe5vPxbE",
        "title": "Spatial Variability of Cyanobacteria and Heterotrophic Bacteria in Lake Taihu (China).",
        "abstract": "Cyanobacterial blooms frequently occur in Lake Taihu (China), but the intertwined relationships between biotic and abiotic factors modulating the frequency and duration of the blooms remain enigmatic. To better understand the relationships between the key abiotic and biotic factors and cyanobacterial blooms, we measured the abundance and diversity of prokaryotic organisms by high-throughput sequencing, the abundance of key genes involved in microcystin production and nitrogen fixation or loss as well as several physicochemical parameters at several stations in Lake Taihu during a cyanobacterial bloom of Microcystis sp.. Measurements of the copy number of denitrification-related genes and 16S rRNA analyses show that denitrification potential and denitrifying bacteria abundance increased in concert with non-diazotrophic cyanobacteria (Microcystis sp.), suggesting limited competition between cyanobacteria and heterotrophic denitrifiers for nutrients, although potential bacteria-mediated N loss may hamper Microcystis growth. The present study provides insight into the importance of different abiotic and biotic factors in controlling cyanobacteria and heterotrophic bacteria spatial variability in Lake Taihu.",
        "keywords": [
            "Cyanobacteria bloom",
            "Bacteria communities",
            "Spatial variability",
            "Nitrogen cycle"
        ],
        "authors": [
            {
                "name": "Haifeng Qian",
                "org": "Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi, 830011, P.R. of China. hfqian@zjut.edu.cn."
            },
            {
                "name": "Tao Lu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, P.R. of China."
            },
            {
                "name": "Hao Song",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, P.R. of China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, QC, G1VOA6, Canada."
            },
            {
                "name": "Jiahui Xu",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, P.R. of China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, P.R. of China."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou, 310032, P.R. of China. panxl@zjut.edu.cn."
            }
        ],
        "venue": "Bulletin of environmental contamination and toxicology",
        "year": 2017
    },
    "RK9V8KHn": {
        "id": "RK9V8KHn",
        "title": "Buffer-Aided Two-Hop Secure Communications With Power Control and Link Selection.",
        "abstract": "This paper investigates the link selection policy for secure communications over a buffer-aided two-hop communication link. It is assumed that a source wishes to send information to a destination with the aid of a trusted half-duplex relay node compromised by an eavesdropper, and that there is no direct link between the source and the destination. The buffer-aided relay forwards the information to...",
        "keywords": [
            "Relays",
            "Power control",
            "Throughput",
            "Wireless communication",
            "Protocols",
            "Radio frequency",
            "Resource management"
        ],
        "authors": [
            {
                "name": "Jing Wan",
                "org": "School of Information Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Deli Qiao",
                "org": "School of Information Science and Technology, East China Normal University, Shanghai, China"
            },
            {
                "name": "Hui-Ming Wang",
                "org": "School of Electronic and Information Engineering, Xi’an Jiaotong University, Xi’an, China"
            },
            {
                "name": "Haifeng Qian",
                "org": "School of Computer Science and Software Engineering, East China Normal University, Shanghai, China"
            }
        ],
        "venue": "IEEE Transactions on Wireless Communications",
        "year": 2018
    },
    "12qvWigd": {
        "id": "12qvWigd",
        "title": "Malicious Activity Detection of a Processing Thread",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "chenyong cher",
                "org": ""
            },
            {
                "name": "eren kursun",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "H7zYOog5": {
        "id": "H7zYOog5",
        "title": "Enantioselective Phytotoxicity of the Herbicide Imazethapyr and its Effect on Rice Physiology and Gene Transcription",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "weiping liu",
                "org": ""
            },
            {
                "name": "haifeng qian",
                "org": ""
            },
            {
                "name": "zhengwei fu",
                "org": ""
            },
            {
                "name": "hanqi ye",
                "org": ""
            },
            {
                "name": "xinliang chen",
                "org": ""
            },
            {
                "name": "tao lu",
                "org": ""
            },
            {
                "name": "haijia hu",
                "org": ""
            },
            {
                "name": "ruiqin wang",
                "org": ""
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2011
    },
    "TPLRXt16": {
        "id": "TPLRXt16",
        "title": "Species-specific response of the soil collembolan gut microbiome and resistome to soil oxytetracycline pollution.",
        "abstract": "Soil antibiotic pollution has caused wide public concern, and the effects of antibiotics on the gut microbiota of soil non-target organisms are poorly understood. Here, we simulate natural exposure scenarios by exposing three species of soil collembolans (Sinella curviseta, Onychiurus yodai, Folsomia candida) to environmentally relevant concentrations of oxytetracycline (OTC) in the soil to explore the response of their gut and surrounding soil microbiota to OTC, including changes in the bacterial community composition and diversity and abundance of antibiotic resistance genes (ARGs). The different collembolan species harbored different gut microbiotas from the surrounding soil. OTC exposure significantly altered the gut microbiota of O. yodai but did not obviously affect that of S. curviseta or F. candida. (o) Entomoplasmatales and Acinetobacter were two main taxa found in O. yodai; the level of the former was significantly increased but that of the latter was reduced with OTC exposure. Moreover, OTC exposure affected the diversity and abundance of ARGs in the gut microbiota of the three collembolan species, with significantly enhanced ARG number and abundance in S. curviseta, especially for genes associated with tetracycline resistance. Our findings indicate that the effects of OTC on soil collembolans are species specific. This study contributes to our understanding of the effects of environmental pollutants on the gut microbiome and resistome of soil animals.",
        "keywords": [
            "Antibiotic resistance genes",
            "Collembolan",
            "Gut microbiota",
            "Non-target organism",
            "Oxytetracycline"
        ],
        "authors": [
            {
                "name": "Qi Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Dong Zhu",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China."
            },
            {
                "name": "Jing Ding",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China."
            },
            {
                "name": "Shuyidan Zhou",
                "org": "Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310014, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2019
    },
    "dEnoHl5n": {
        "id": "dEnoHl5n",
        "title": "Distinct physiological and molecular responses in Arabidopsis thaliana exposed to aluminum oxide nanoparticles and ionic aluminum.",
        "abstract": "Nano-aluminium oxide (nAlO) is one of the most widely used nanomaterials. However, nAlO toxicity mechanisms and potential beneficial effects on terrestrial plant physiology remain poorly understood. Such knowledge is essential for the development of robust nAlO risk assessment. In this study, we studied the influence of a 10-d exposure to a total selected concentration of 98 μM nAlO or to the equivalent molar concentration of ionic Al (AlCl) (196 μM) on the model plant Arabidopsis thaliana on the physiology (e.g., growth and photosynthesis, membrane damage) and the transcriptome using a high throughput state-of-the-art technology, RNA-seq. We found no evidence of nAlO toxicity on photosynthesis, growth and lipid peroxidation. Rather the nAlO treatment stimulated root weight and length by 48% and 39%, respectively as well as photosynthesis opening up the door to the use of nAlO in biotechnology and nano agriculture. Transcriptomic analyses indicate that the beneficial effect of nAlO was related to an increase in the transcription of several genes involved in root growth as well as in root nutrient uptake (e.g., up-regulation of the root hair-specific gene family and root development genes, POLARIS protein). By contrast, the ionic Al treatment decreased shoot and root weight of Arabidopsis thaliana by 57.01% and 45.15%, respectively. This toxic effect was coupled to a range of response at the gene transcription level including increase transcription of antioxidant-related genes and transcription of genes involved in plant defense response to pathogens. This work provides an integrated understanding at the molecular and physiological level of the effects of nAlO and ionic Al in Arabidopsis.",
        "keywords": [
            "AlCl(3)",
            "Arabidopsis thaliana",
            "Oxidative stress",
            "Transcriptomics",
            "nAl(2)O(3)"
        ],
        "authors": [
            {
                "name": "Yujian Jin",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xiaoji Fan",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Xingxing Li",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhenyan Zhang",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Liwei Sun",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Zhengwei Fu",
                "org": "College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Michel Lavoie",
                "org": "Quebec-Ocean and Takuvik Joint International Research Unit, Université Laval, Québec, Canada."
            },
            {
                "name": "Xiangliang Pan",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China."
            },
            {
                "name": "Haifeng Qian",
                "org": "College of Environment, Zhejiang University of Technology, Hangzhou 310032, PR China; Xinjiang Key Laboratory of Environmental Pollution and Bioremediation, Chinese Academy of Sciences, Urumqi 830011, PR China. Electronic address: hfqian@zjut.edu.cn."
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2017
    },
    "WHpe0h2S": {
        "id": "WHpe0h2S",
        "title": "MTHFR genotypes and breast cancer survival after surgery and chemotherapy: A report from the Shanghai Breast Cancer Study",
        "abstract": "Methylenetetrahydrofolate reductase (MTHFR) regulates the intracellular folates pool for DNA synthesis and methylation. Sequence variations in MTHFR (nucleotides 677 (C&RARR; T) and 1298 (A&RARR; C)) result in allozymes with decreased activity. The 677TT genotype is associated with increased toxicity of methotrexate and increased clinical response to 5-fluorouracil in treatment of cancers including breast cancer. We evaluated MTHFR genotypes and breast cancer survival in a cohort of 1067 Chinese women diagnosed with breast cancer between 1996 and 1998 who received surgery and chemotherapy. Life table method was used to calculate 5-year survival rates. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) after adjusting for potential confounding factors. Median follow-up time was 5.2 years; 5-year survival was 84.6%. Sixty-six percent carried a 677T allele and 31% carried a 1298 C allele. We found that overall 5-year breast cancer survival did not differ significantly across all genotypes (85.3% for 677 CC and 83.8% for 677TT; 83.8% for 1298 AA and 79.1% for 1298 CC). However, carrying the 677T allele was associated with non-significant increased risk of death for subjects with late stage disease (stages III-IV) (HR=1.80, 95% CI: 0.79-4.14 for TT vs. CC, p for trend=0.15), particularly among those who had survived past the second year (HR=2.97, 95% CI: 1.10-7.98, p for trend=0.04). The A1298C genotypes were not significantly associated with risk of death. This study suggests that the MTHFR C677T polymorphisms may affect long-term survival from advanced breast cancer.",
        "keywords": [
            "breast neoplasms",
            "gene",
            "MTHFR",
            "survival"
        ],
        "authors": [
            {
                "name": "Martha J. Shrubsole",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Zhi Xian Ruan",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Qi Niu",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yutang Gao -",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            }
        ],
        "venue": "BREAST CANCER RESEARCH AND TREATMENT",
        "year": 2005
    },
    "qXD1Pmc9": {
        "id": "qXD1Pmc9",
        "title": "Abstract LB-296: Tumor tissue microRNA expression in association with triple negative breast cancer recurrence and mortality",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yan liu",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "qiuyin cai",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "fei ye",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "jie wu",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "yinghao su",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "pingping bao",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "wei lu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university school of medicine"
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "I8v43DwD": {
        "id": "I8v43DwD",
        "title": "Probe into leachate treatment scale for municipal solid waste landfill",
        "abstract": "In this paper,different ways for municipal solid waste(MSW) landfill leachate production were studied.Taking the MSW filling process and outside landfill effecting factors as study objects,based on infiltration method,the formula for annual average method leachate production prediction was proposed,according to which the MSW landfill leachate treatment scale was determined.Then,based on the practical engineering project,the leachate production prediction method reliability was tested.",
        "keywords": [
            "Annual average method",
            "Infitration method",
            "Leachate production",
            "Municipal solid waste filling",
            "Treatment scale",
            "Landfill leachate"
        ],
        "authors": [
            {
                "name": "Xiong Xiangyang",
                "org": "China Urban Construction Design & Research Institute,Beijing ,China"
            },
            {
                "name": "Cai Hui",
                "org": "China Urban Construction Design & Research Institute,Beijing ,China"
            },
            {
                "name": "Chen Gang",
                "org": "China Urban Construction Design & Research Institute,Beijing ,China"
            },
            {
                "name": "Zhang Haiyu",
                "org": "China Urban Construction Design & Research Institute,Beijing ,China"
            }
        ],
        "venue": "Water & Wastewater Engineering",
        "year": 2011
    },
    "tgQ4OVa8": {
        "id": "tgQ4OVa8",
        "title": "Central Adiposity and Mortality: A Report from the Shanghai Women's Health Study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xianglan Zhang",
                "org": ""
            },
            {
                "name": "X O Shu",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Qi Li",
                "org": ""
            },
            {
                "name": "Y. T. Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "AMERICAN JOURNAL OF EPIDEMIOLOGY",
        "year": 2006
    },
    "KfMK5AN3": {
        "id": "KfMK5AN3",
        "title": "The Effect of Curcumin on the Immune Organ Weight and Pathomorphology of Adjuvant Arthritis Rats",
        "abstract": "Objective:To explore the immune organ weight and the pathological changes of the synovium of Adjuvant Arthritis(AA) rats by HE staining,and to discuss immune pharmacodynamics of curcumin.Methods:SD rats induced by Freunds complete adjuvant were divided into three groups: normal,control and curcumin group.The curcumin group was given curcumin by peritoneal injection.The rats were executed at 15th d after weighing,and then took the synovium for pathological examination.The thymus and spleen were weighed by electronic balance.Results:The synovium pathomorphology indicate that infiltration of inflammatory cells of curcumin group was significantly slighter than control group.The thymic weight of curcumin group was also obviously lower than control group.Conclusion:The curcumin can decrease infiltration of inflammatory cells of AA rats,and activate immunosuppression by reducing thymus weight.",
        "keywords": [
            "Curcumin",
            "Immune organ weight",
            "Adjuvant arthritis",
            "Synovium pathomorphology"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            },
            {
                "name": "ZHENG Zhao-ling",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            },
            {
                "name": "SHANG Wei",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            }
        ],
        "venue": "Journal of Emergency in Traditional Chinese Medicine",
        "year": 2009
    },
    "yOGiLpWX": {
        "id": "yOGiLpWX",
        "title": "Predictors and long-term reproducibility of urinary phthalate metabolites in middle-aged men and women living in urban Shanghai",
        "abstract": "Phthalate esters are man-made chemicals commonly used as plasticizers and solvents, and humans may be exposed through ingestion, inhalation, and dermal absorption. Little is known about predictors of phthalate exposure, particularly in Asian countries. Because phthalates are rapidly metabolized and excreted from the body following exposure, it is important to evaluate whether phthalate metabolites measured at a single point in time can reliably rank exposures to phthalates over a period of time. We examined the concentrations and predictors of phthalate metabolite concentrations among 50 middle-aged women and 50 men from two Shanghai cohorts, enrolled in 1997–2000 and 2002–2006, respectively. We assessed the reproducibility of urinary concentrations of phthalate metabolites in three spot samples per participant taken several years apart (mean interval between first and third sample was 7.5years [women] or 2.9years [men]), using Spearman's rank correlation coefficients and intra-class correlation coefficients. We detected ten phthalate metabolites in at least 50% of individuals for two or more samples. Participant sex, age, menopausal status, education, income, body mass index, consumption of bottled water, recent intake of medication, and time of day of collection of the urine sample were associated with concentrations of certain phthalate metabolites. The reproducibility of an individual's urinary concentration of phthalate metabolites across several years was low, with all intra-class correlation coefficients and most Spearman rank correlation coefficients ≤0.3. Only mono(2-ethylhexyl) phthalate, a metabolite of di(2-ethylhexyl) phthalate, had a Spearman rank correlation coefficient ≥0.4 among men, suggesting moderate reproducibility. These findings suggest that a single spot urine sample is not sufficient to rank exposures to phthalates over several years in an adult urban Chinese population.",
        "keywords": [
            "Phthalates",
            "Reproducibility",
            "Predictors",
            "Food contaminants",
            "Personal care products"
        ],
        "authors": [
            {
                "name": "anne p starling",
                "org": "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA"
            },
            {
                "name": "lawrence s engel",
                "org": "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA"
            },
            {
                "name": "antonia m calafat",
                "org": "Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA"
            },
            {
                "name": "stella koutros",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA"
            },
            {
                "name": "jaya m satagopan",
                "org": "Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"
            },
            {
                "name": "g yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA"
            },
            {
                "name": "charles e matthews",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA"
            },
            {
                "name": "qiuyin cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA"
            },
            {
                "name": "jessie p buckley",
                "org": "Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA"
            },
            {
                "name": "butian ji",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA"
            },
            {
                "name": "hui cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA"
            },
            {
                "name": "wongho chow",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA"
            },
            {
                "name": "wei zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA"
            },
            {
                "name": "y gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, China"
            },
            {
                "name": "nathaniel rothman",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA"
            },
            {
                "name": "yongbing xiang",
                "org": "Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"
            },
            {
                "name": "xiaoou shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA"
            }
        ],
        "venue": "Environment International",
        "year": 2015
    },
    "xd9waLAC": {
        "id": "xd9waLAC",
        "title": "Association of leisure-time physical activity with total and cause-specific mortality: a pooled analysis of nearly a half million adults in the Asia Cohort Consortium.",
        "abstract": "Regular participation in LTPA is associated with reduced mortality in middle-aged and elder Asians regardless pre-existing health conditions.",
        "keywords": "",
        "authors": [
            {
                "name": "Ying Liu",
                "org": "Division of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, TN, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, TN, USA."
            },
            {
                "name": "Wanqing Wen",
                "org": "Division of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, TN, USA."
            },
            {
                "name": "Eiko Saito",
                "org": "Division of Cancer Statistics Integration, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "M Shafiur Rahman",
                "org": "Department of Global Health Policy, University of Tokyo, Tokyo, Japan."
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Epidemiology and Prevention Group, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Akiko Tamakoshi",
                "org": "Graduate School of Medicine, Hokkaido University, Sapporo, Japan."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, PR China."
            },
            {
                "name": "Jian-Min Yuan",
                "org": "Division of Cancer Control and Population Science, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, PR China."
            },
            {
                "name": "Ichiro Tsuji",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Seiki Kanemura",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Chisato Nagata",
                "org": "Graduate School of Medicine, Gifu University, Gifu, Japan."
            },
            {
                "name": "Myung-Hee Shin",
                "org": "Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea."
            },
            {
                "name": "Wen-Harn Pan",
                "org": "Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan."
            },
            {
                "name": "Woon-Puay Koh",
                "org": "Saw Swee Hock School of Public Health, Singapore, Republic of Singapore."
            },
            {
                "name": "Norie Sawada",
                "org": "Epidemiology and Prevention Group, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, TN, USA."
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, PR China."
            },
            {
                "name": "Yasutake Tomata",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Yumi Sugawara",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Keiko Wada",
                "org": "Graduate School of Medicine, Gifu University, Gifu, Japan."
            },
            {
                "name": "Yoon-Ok Ahn",
                "org": "Department of Preventive Medicine."
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Armed Forces Capital Hospital, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Habibul Ashan",
                "org": "Departments of Health Studies, Medicine and Human Genetics and Cancer Research Center, University of Chicago, Chicago, IL, USA."
            },
            {
                "name": "Kee Seng Chia",
                "org": "Saw Swee Hock School of Public Health, Singapore, Republic of Singapore."
            },
            {
                "name": "Paolo Boffetta",
                "org": "Icahn School of Medicine at Mount Sinai, New York, NY, USA."
            },
            {
                "name": "Manami Inoue",
                "org": "Epidemiology and Prevention Group, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Daehee Kang",
                "org": "Cancer Research Institute, Seoul National University, Seoul, South Korea."
            },
            {
                "name": "John D Potter",
                "org": "Department of Epidemiology, University of Washington, Seattle, WA, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Nashville, TN, USA."
            }
        ],
        "venue": "International journal of epidemiology",
        "year": 2018
    },
    "SeEt7sr7": {
        "id": "SeEt7sr7",
        "title": "Depressive symptoms and their association with social determinants and chronic diseases in middle-aged and elderly Chinese people.",
        "abstract": "Depression is one of the most prevalent mental disorders worldwide. Little information is available regarding association of depressive symptoms (DS) with cancer and chronic diseases among middle-aged and elderly Chinese in a population-based setting. In this study we evaluated the prevalence and examined correlates of DS in two population-based cohort studies. Included in the analyses were 103,595 people with a mean age of 61.8 years at the DS assessment. The prevalence of DS was 2.4% in men and 5.6% in women. We found elderly participants, those with lower BMI, or chronic diseases were more likely to experience DS. Having a history of stroke (odds ratio (OR) = 2.2 in men and 1.8 in women), cancer (OR = 3.3 in men and 1.9 in women), or Parkinson's disease (OR = 3.1 in men and 2.7 in women) was associated with high DS. In women, high income and high education levels were inversely related to DS. Being a single woman, long-term or heavy female smoker was associated with high prevalence of DS. High BMI was correlated with low prevalence of depression in men. Our data suggests a low prevalence of DS among middle-aged and elderly people in Shanghai, China. Age, education, income, marital status, smoking, BMI, and certain health conditions were associated with DS.",
        "keywords": "",
        "authors": [
            {
                "name": "Qiaolan Liu",
                "org": "West China School of Public Health, Sichuan University, Chengdu, Sichuan, China."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States. hui.cai@vanderbilt.edu."
            },
            {
                "name": "Lawrence H Yang",
                "org": "Department of Social and Behavioral Sciences, College of Global Public Health, New York University, New York, NY, United States."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Cancer Institute of Shanghai Jiao Tong University, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States."
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology, Cancer Institute of Shanghai Jiao Tong University, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Cancer Institute of Shanghai Jiao Tong University, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States."
            },
            {
                "name": "Ezra Susser",
                "org": "Department of Social and Behavioral Sciences, College of Global Public Health, New York University, New York, NY, United States."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, United States."
            }
        ],
        "venue": "Scientific reports",
        "year": 2018
    },
    "nPgzuwIi": {
        "id": "nPgzuwIi",
        "title": "Protective Effect of Acupuncture by Upregulating Signals of Adiponectin on Aorta in High-fat Dietary Induced Rats",
        "abstract": "Objective To study the effect of high-fat dietary on aortal adiponectin signal in Sprague Dawley rats,and in which whether acupncture can regulate it.Method Seventeen 3-week Sprague Dawley rats raised with high-fat dietary for 12 weeks were divided into acupuncture group and model group according to body weight.Serum level of adiponectin was detected with ELISA,aortal mRNA expressions and protein contents of adipoR1/2 were examined with real-time PCR and western blotting respectively,and aortal intimal contents of bcl-2 and bax were detected with immunohistochemistry after 4-week treatment.Simultaneously,the aortal contents of NO,SOD,MDA and the activity of NOS were examined.And rats raised with normal dietary were as the control.Result Compared with the control,serum level of adiponcetin,mRNA expressions and protein contents of adipoR1/2,the contents of NO,SOD,bcl-2 and the activity of cNOS in aorta decreased significantly,while aortal contents of MDA and bax increased obviously in model.Serum level of adiponcetin,mRNA expression and protein content of adipoR2,the contents of NO,SOD,bcl-2 and the activity of cNOS in aorta in acupuncture group were higher than that in model group,aortal contents of MDA and bax in acupuncture group was lower than that in model group.Conclusion High-fat dietary induces depressed aortal signal transduction of adiponectin in Sprague Dawley rats.Acupuncture increases aortal signal transmission of adiponectin through upregualting mRNA expression and protein content of adipoR2,thus protects aorta against damage due to high-fat dietary.",
        "keywords": [
            "acupuncture",
            "high-fat dietary",
            "rats",
            "signal of adiponectin",
            "aorta"
        ],
        "authors": [
            {
                "name": "YUAN Ai-hong",
                "org": "Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Information on Traditional Chinese Medicine",
        "year": 2011
    },
    "5JRJd8SL": {
        "id": "5JRJd8SL",
        "title": "Abstract 3281: TGFβ pathway alteration, body mass index, physical activity and breast cancer outcomes: The Shanghai Breast Cancer Survival Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yinghao su",
                "org": "vanderbilt university"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "qingchao qiu",
                "org": "vanderbilt university"
            },
            {
                "name": "wei lu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university"
            },
            {
                "name": "qiuyin cai",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "WLm9BDoY": {
        "id": "WLm9BDoY",
        "title": "Study of the effect of captopril on myocardial fibrosis in rat with pressure overload",
        "abstract": "Objective It is to observe the effects of captopril on regressing myocardial fibrosis in rat with pressure overload.Methods The model of left ventricular remodeling in rat with pressure overload was made by abdominal aortic constriction.36 SD male rats were randomly divided into three groups: sham operation group,model group and captopril group.After treatment for 4 weeks,it was observed that the changes of left ventricular myocardium collagen pathological coloring,left ventricular interstitial cardiac tissue ultramicrostructure,left ventricular cardiac tissue collagen type Ⅰ immunohistochemistry coloring and collagen type Ⅲ immunohistochemistry coloring.Results The average optic density of left ventricular cardiac tissue typeⅠcollagen and type Ⅲ collagen of model group were increased obviously than that of sham operation group(P<0.01).The average optic density of left ventricular cardiac tissue typeⅠcollagen and type Ⅲ collagen of captopril group was lower than that of model group significantly(P<0.01).The changes of left ventricular myocardium collagen pathological coloring and left ventricular interstitial cardiac tissue ultramicrostructure were consistent with those of typeⅠcollagen and type Ⅲ collagen.Conclusion Captopril has effects on regressing myocardial fibrosis.",
        "keywords": [
            "collagen type Ⅲ",
            "collagen type Ⅰ",
            "pressure overload",
            "captopril",
            "myocardial fibrosis"
        ],
        "authors": [
            {
                "name": "Zhao Zhiming",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Guo Junhao",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Shang Wei",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Dong Xiaolei",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zhang Qunyan",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2010
    },
    "xKTdu9fd": {
        "id": "xKTdu9fd",
        "title": "Quantifying the association of low-intensity and late initiation of tobacco smoking with total and cause-specific mortality in Asia.",
        "abstract": "Our study showed that smokers who smoked a small number of cigarettes or started smoking later in life also experienced significantly elevated all-cause and major cause-specific mortality but benefited from cessation. There is no safe way to smoke-not smoking is always the best choice.",
        "keywords": [
            "prevention",
            "smoking caused disease",
            "socioeconomic status"
        ],
        "authors": [
            {
                "name": "Jae Jeong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Danxia Yu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Neal D Freedman",
                "org": "Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA."
            },
            {
                "name": "Wanqing Wen",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Shafiur Rahman",
                "org": "Division of Prevention, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Sarah K Abe",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Eiko Saito",
                "org": "Division of Cancer Statistics and Integration, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Prakash C Gupta",
                "org": "Healis Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India."
            },
            {
                "name": "Jiang He",
                "org": "Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA."
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Jian-Min Yuan",
                "org": "Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA."
            },
            {
                "name": "Yasutake Tomata",
                "org": "Division of Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan."
            },
            {
                "name": "Ichiro Tsuji",
                "org": "Division of Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan."
            },
            {
                "name": "Yumi Sugawara",
                "org": "Division of Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan."
            },
            {
                "name": "Keitaro Matsuo",
                "org": "Division of Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan."
            },
            {
                "name": "Yoon-Ok Ahn",
                "org": "Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Sue K Park",
                "org": "Cancer Research Institute, Seoul National University, Seoul, South Korea."
            },
            {
                "name": "Yu Chen",
                "org": "Department of Population Health, New York University School of Medicine, New York, NY, USA."
            },
            {
                "name": "Wen-Harn Pan",
                "org": "Institute of Biomedical Sciences, Academia Sinica BRC, Taipei, Taiwan."
            },
            {
                "name": "Mangesh Pednekar",
                "org": "Healis Sekhsaria Institute for Public Health, Navi Mumbai, Maharashtra, India."
            },
            {
                "name": "Dongfeng Gu",
                "org": "Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China."
            },
            {
                "name": "Norie Sawada",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Hong-Lan Li",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Woon-Puay Koh",
                "org": "Saw Swee Hock School of Public Health, National University of Singapore, Singapore."
            },
            {
                "name": "Renwei Wang",
                "org": "Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA."
            },
            {
                "name": "Shu Zhang",
                "org": "Division of Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan."
            },
            {
                "name": "Seiki Kanemura",
                "org": "Division of Epidemiology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan."
            },
            {
                "name": "Hidemi Ito",
                "org": "Division of Descriptive Cancer Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan."
            },
            {
                "name": "Myung-Hee Shin",
                "org": "Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea."
            },
            {
                "name": "Pei-Ei Wu",
                "org": "Institute of Biomedical Sciences, Academia Sinica BRC, Taipei, Taiwan."
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Habibul Ahsan",
                "org": "Department of Health Studies, Center for Cancer Epidemiology and Prevention, University of Chicago, Chicago, IL, USA."
            },
            {
                "name": "Kee Seng Chia",
                "org": "Saw Swee Hock School of Public Health, National University of Singapore, Singapore."
            },
            {
                "name": "Paolo Boffetta",
                "org": "Icahn School of Medicine at Mount Sinai, New York, NY, USA."
            },
            {
                "name": "Manami Inoue",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Daehee Kang",
                "org": "Cancer Research Institute, Seoul National University, Seoul, South Korea."
            },
            {
                "name": "John D Potter",
                "org": "Department of Epidemiology, University of Washington, Seattle, WA, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA wei.zheng@vanderbilt.edu."
            }
        ],
        "venue": "Tobacco control",
        "year": 2020
    },
    "Qh8as6pr": {
        "id": "Qh8as6pr",
        "title": "Changes of Neuroendocrine System and Cytokines in the Rats with Isoproterenol-induced Chronic Heart Failure",
        "abstract": "Objective To establish the animal model of isoproterenol(ISO)-induced chronic heart failure in rats and to study the changes of neuroendocrine system and cytokines.Methods Male Sprague-Dawley rats were randomly allocated to the ISO-induced chronic heart failure group(ISO group,n=50)receiving two subcutaneous injections of 170mg ISO per kilogram of body and the healthy control group(CON group,n=10)receiving two subcutaneous injections of 0.25ml normal saline.At 18th week,the left ventricular ejection fraction(LVEF),left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD)and fractional shortening(FS)were assessed by echocardiogram.Norepinephrine(NE),angiotensionⅡ(ANGⅡ),aldosterone(ALD)and TNF-α in plasma were all detected.18 weeks later,the mass ratio of heart ventricle and left ventricle to body was measured.Results Compared with the CON group,the LVEF,FS significantly decreased and the LVEDD,LVESD enlarged notably in ISO group(P<0.01).Also the mass ratio of left ventricle to body and the concentration of NE,ANGⅡ,ALD and TNF-α increased distinctly(P<0.01).Conclusion Activation of neuroendocrine system and cytokines was observed in high-dose isoproterenol-induction rat model of CHF.",
        "keywords": [
            "Rats",
            "Cytokine",
            "Neuroendocrine",
            "Echocardiography",
            "Chronic heart failure",
            "Isoproterenol"
        ],
        "authors": [
            {
                "name": "CHEN Xiang-min",
                "org": "Department of Cardiology,Traditional Chinese Medicine Hospital of Nanjing,Nanjing ,China"
            },
            {
                "name": "SONG Yao-hong",
                "org": "Department of Cardiology,Traditional Chinese Medicine Hospital of Nanjing,Nanjing ,China"
            },
            {
                "name": "SHEN Si-Yu",
                "org": "Department of Cardiology,Traditional Chinese Medicine Hospital of Nanjing,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Cardiology,Traditional Chinese Medicine Hospital of Nanjing,Nanjing ,China"
            }
        ],
        "venue": "Journal of Chinese Microcirculation",
        "year": 2008
    },
    "JFzoAA8W": {
        "id": "JFzoAA8W",
        "title": "The changes of plasma aldosterone in rats model with abdominal aortic banding",
        "abstract": "Aim To establish abdominal aortic banding rats model and to determine the concentration of aldosterone in myocardial fibrosis.Methods 14 SD rats were taken out randomly as sham-operation group in 30 SD rats,and 16 rats were model group.Myocardial fibrosis rat model was established by partially banding abdominal aorta with silver clip(inside diameter 0.7 mm) according to Doering,s method.Left ventricular mass index(LVMI) was calculated and left ventricular ultrastructure was observed with electron microscope.The level of ALD was detected by radioimmunoassay.Results In the 8th week,left ventricular ultrastructure alteration was obvious in model groups.LVMI and the level of ALD were increased obviously in model group,compared with sham-operation group(P<0.01).Conclusion In the 8th week,the rats myocardium alterations fit myocardial fibrosis after abdominal aortic banding,which may be related to the accrescence of ALD.",
        "keywords": [
            "ultrastructure",
            "aldosterone",
            "abdominal aortic banding",
            "myocardial fibrosis"
        ],
        "authors": [
            {
                "name": "JIAO Dong-dong",
                "org": "School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjng Military Command,Nanjing "
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjng Military Command,Nanjing "
            },
            {
                "name": "ZHANG Yong-wen",
                "org": "School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjng Military Command,Nanjing "
            },
            {
                "name": "LU Le",
                "org": "School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjng Military Command,Nanjing "
            },
            {
                "name": "CAI Hui",
                "org": "School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjng Military Command,Nanjing "
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2009
    },
    "Nz4kxbN6": {
        "id": "Nz4kxbN6",
        "title": "Abstract 4254: Associations of sleep, quality of life and energy level with breast cancer mortality and recurrence: The Shanghai Breast Cancer Survival Study",
        "abstract": "Background: Sleep disorder is highly prevalent among breast cancer patients. Whether sleep disorder is associated with breast cancer prognosis has rarely been investigated. The objective of this study is to prospectively assess the association of self-reported sleep difficulty and sleep quality with total mortality and breast-cancer specific mortality/recurrence in the Shanghai Breast Cancer Survival Study.  Methods: This study included 4,219 women with stage I-III breast cancer diagnosed at an age between 20 to 75 years. Information on sleep attributes was collected at approximately 18 months and 36 months after breast cancer diagnosis. Information on disease recurrence and survival status was obtained via in-person follow-up and via record linkage with vital statistics registry data. Cox proportional hazard model was used to derive hazard ratios (HR) and confidence intervals (CIs) for all-cause mortality and breast cancer-specific mortality/recurrence. Stratified analyses according to self-reported overall quality of life, depression and energy level assessed at 18 months were also conducted.  Results: During a median follow-up of 9.8 years (range: 0.1-12.2 years), 757 deaths due to any causes and 672 breast cancer recurrences or related deaths were recorded after the 18-month post-diagnosis survey. Sleep difficulty and low sleep quality were not significantly associated with total or breast-cancer specific mortality/recurrence. The respective HRs were 0.98 (95% CI: 0.79, 1.22) and 1.01 (95% CI: 0.77, 1.31) for total mortality and 1.04 (95% CI: 0.82, 1.31) and 0.93 (95% CI: 0.69, 1.26) for breast cancer-specific mortality/recurrence. On the other hand, low quality of life, depression and low energy level were significantly associated with increased total mortality, with HRs of 3.19 (2.45, 4.15), 1.61 (1.21, 2.14) and 1.53 (1.23, 1.91), respectively. These three factors did not modify the association of sleep measurements with breast cancer outcomes (all P-interactions u003e 0.10).  Conclusions: In a large population-based cohort study, we did not observe any significant association of sleep difficulty and poor sleep quality with increased risk of death and recurrence in breast cancer patients. Instead, low quality of life and energy level were found to be associated with disease prognosis and thus they could be important indicators for targeting population with poor breast cancer prognosis.   Citation Format:  Jingjing Zhu, Pingping Bao, Hui Cai, Liang Shi, Ying Zheng, Wei Zheng, Xiao-ou Shu. Associations of sleep, quality of life and energy level with breast cancer mortality and recurrence: The Shanghai Breast Cancer Survival Study [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4254.",
        "keywords": "",
        "authors": [
            {
                "name": "Jingjing Zhu",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Liang Shi",
                "org": "Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University, Nashville, TN;"
            }
        ],
        "venue": "Cancer Research",
        "year": 2018
    },
    "25IZoPUu": {
        "id": "25IZoPUu",
        "title": "Questions about Zhuque Decoction",
        "abstract": "\"Treatise on Febrile Diseases\" includes all prescriptions named with four god beasts except the Zhuque Decoction.Most doctors in ancient times agreed that the Zhuque Decoction indeed existed,but without agreement on what it was.Some considered the Zhuque Decoction as Shizao Decoction that comprised ten Chinese dates in each formula,and some thought it was Huanglian E'jiao Decoction that comprised Coptis chinensis and donkey-hide glue.Given the literature and principles of medical science,it is more reasonable to regard Zhuque Decoction as Huanglian E'jiao Decoction.",
        "keywords": [
            "Huanglian E'jiao Decoction",
            "Zhuque Decoction",
            "Treatise on Febrile Diseases"
        ],
        "authors": [
            {
                "name": "ZHAO Chun-jiang",
                "org": "Department of Traditional Chinese Medicine,General Hospital of Nanjing,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Traditional Chinese Medicine,General Hospital of Nanjing,PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2012
    },
    "4Eig9KIZ": {
        "id": "4Eig9KIZ",
        "title": "Effect of basic fibroblast growth factor on proliferation and differentiation of monkey bone marrow mesenchymal stem cells into neuronal precursor cells:Does the concentration affect cryptotanshinone induction?",
        "abstract": "BACKGROUND: Basic fibroblast growth factor (bFGF) belongs to active peptide, which is an effective mitogenic factor. OBJECTIVE: To investigate the effect of bFGF on proliferation and differentiation of monkey bone marrow mesenchymal stem cells (BMMSCs) into neuronal precursor cells. METHODS: Monkey BMMSCs were in vitro cultured by density gradient centrifugation, and then divided into 4 groups after passaged, namely, control, bFGF with low, medium and high concentration groups. In the bFGF groups, 0, 3, 6, 10 μg/L bFGF were applied. The proliferation of BMMSCs in each group were observed. The 5th BMMSCs were cultured with serum free L-DMEM culture medium containing 20 mg/L cryptotanshinone to differentiated into neural-like cells. The expression of positive-nestin protein was detected by immunohistochemical method. RESULTS AND CONCLUSION: Compared with the control group, proliferation rate of BMMSCs in the bFGF groups were accelerated (P < 0.05), which showed a positive correlation to the concentration of bFGF. The positive-nestin protein could be found in the low and medium concentration groups at 0.5 hours after induction, and reached a peak at 1.5 hours, which increased obviously in the low concentration group than that of the high concentration group (P < 0.05). bFGF can promote BMMSCs proliferation in vitro, enhance inducing ratio of prophase neuron-like cells at lower concentration but inhibit differentiation at high level.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Liu Xiao-gang",
                "org": "Department of Pathology, Chuiyangliu Hospital, Beijing , China"
            },
            {
                "name": "Deng Yu-bin",
                "org": "Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou , Guangdong Province, China"
            },
            {
                "name": "Cai Hui",
                "org": "Department of Pathology, Chuiyangliu Hospital, Beijing , China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2010
    },
    "pO3aGEWT": {
        "id": "pO3aGEWT",
        "title": "Abstract 633: Association between saturated fat intakes and lung cancer risk among low-income populations in the Southeastern United States",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hyung-Suk Yoon",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Jae Jeong Yang",
                "org": ""
            },
            {
                "name": "Danxia Yu",
                "org": ""
            },
            {
                "name": "Harvey J. Murff",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "William J. Blot",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            }
        ],
        "venue": "Epidemiology",
        "year": 2019
    },
    "6kydcufl": {
        "id": "6kydcufl",
        "title": "The Influence of Hyperlipoidemia on Bax and Bcl-2 Protein Expression in Rat Aortic Endothelial Cells",
        "abstract": "Objective:To study the change of Bax and Bcl-2 protein expression in hyperlipoidemia rat aortic endothelial cells and the possible mechanism of promoting endothelial cells apoptosis.Method:17 male Sprague Dawley rats were randomly divided into hyperlipoidemia model group(n=8) and control group(n=9),respectively raised for 16w with high-fat diets and normal diets.Serum lipid level of all rats was measured and apoptosis protein of Bax and Bcl-2 on the aortic endothelium cell were analyzed by immunohistochemical method,while using HE staining and electron microscopy to observe aortic pathological changes.Results:Compared with the control group,serem levels of TG,TC increased in model group(P<0.01).The expression of Bax protein on aortic endothelial was significantly higher(P<0.01),the Bcl-2 protein and ratio of Bcl-2/Bax was markedly lower than control group(P<0.01).Moreover model group aortic thickening and smooth muscle cell proliferation,most of aortal endothelial tissue falled out,plasmalemma of endotheliocyte ruptured,cytoplasm deleted,nuclear membrane was incomplete.Conclusion:Hyperlipoidemia can increase endothelial damage and induce apoptosis,accelerate the formation of atherosclerotic pathological process through regulating the expression of apoptosis protein Bax and Bcl-2 and the ratio of Bcl-2/Bax on aortic endothelial cell.",
        "keywords": [
            "Atherosclerosis",
            "Endothelial cells",
            "Apoptosis protein Bax/Bcl-2",
            "Hyperlipoidemia"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Zhao Lingjie",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Zhao Zhiming",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2011
    },
    "y374LgMt": {
        "id": "y374LgMt",
        "title": "Modifying effect of calcium/magnesium intake ratio and mortality: A populationbased cohort study",
        "abstract": "Objectives: Magnesium (Mg) and calcium (Ca) antagonise each other in (re)absorption, inflammation and many other physiological activities. Based on mathematical estimation, the absorbed number of Ca or Mg depends on the dietary ratio of Ca to Mg intake. We hypothesise that the dietary Ca/Mg ratio modifies the effects of Ca and Mg on mortality due to gastrointestinal tract cancer and, perhaps, mortality due to diseases occurring in other organs or systems. Design: Prospective studies. Setting: Population-based cohort studies (The Shanghai Women's Health Study and the Shanghai Men's Health Study) conducted in Shanghai, China. Participants: 74 942 Chinese women aged 40-70 years and 61 500 Chinese men aged 40-74 years participated in the study. Primary outcome measures: All-cause mortality and disease-specific mortality. Results: In this Chinese population with a low Ca/Mg intake ratio (a median of 1.7 vs around 3.0 in US populations), intakes of Mg greater than US Recommended Daily Allowance (RDA) levels (320 mg/day among women and 420 mg/day among men) were related to increased risks of total mortality for both women and men. Consistent with our hypothesis, the Ca/Mg intake ratio significantly modified the associations of intakes of Ca and Mg with mortality risk, whereas no significant interactions between Ca and Mg in relation to outcome were found. The associations differed by gender. Among men with a Ca/Mg ratio >1.7, increased intakes of Ca and Mg were associated with reduced risks of total mortality, and mortality due to coronary heart diseases. In the same group, intake of Ca was associated with a reduced risk of mortality due to cancer. Among women with a Ca/Mg ratio ≤1.7, intake of Mg was associated with increased risks of total mortality, and mortality due to cardiovascular diseases and colorectal cancer. Conclusions: These results, if confirmed, may help to understand the optimal balance between Ca and Mg in the aetiology and prevention of these common diseases and reduction in mortality.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Qi Dai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xinqing Deng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Martha J. Shrubsole",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Butian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wongho Chow -",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "BMJ Open",
        "year": 2013
    },
    "8Nvz55KS": {
        "id": "8Nvz55KS",
        "title": "Biofilm observation and distribution investigation of β-defensins in Pneumocystis cariniipneumonia in rat",
        "abstract": "To investigate the distribution of β-defensins mRNA and observe the biofilm of Pneumocystis carinii in vivo in rat,P.carinii pneumonia(PCP) in rats was induced by using dexamethasone in this study.P.carinii was detected by GMS stain and reverse transcription PCR.The biofilm of P.carinii in vivo was observed by silver stain,periodic acid-schiff(PAS) stain and scanning electron microscope(SEM).β-defensin-1 and β-defensin-2 mRNA were tested by reverse transcription PCR in rat lung,kidney,spleen,small intestine,skin,liver,heart and blood of 8 various organs and tissues.The results showed that P.carinii could be found as early as after 5 weeks using dexamethasone by RT-PCR,after 7 weeks by GMS stain,and biofilm formation after 9 weeks by using dexamethasone,respectively.β-defensin-1 and β-defensin-2 were both found in all 8 PCP organs.Among them,β-defensin-1 and β-defensin-2 mRNA contents were relatively rich in kidney and skin,and in lung,respectively.It is demonstrated that P.carinii could form biofilm and induceβ-defensin in PCP rats,especially for β-defensin-2 in lung tissue.",
        "keywords": [
            "biofilm",
            "Pneumocystis carinii",
            "rat model",
            "β-defensin"
        ],
        "authors": [
            {
                "name": "ZHENG Yu-qiang",
                "org": "Medicine Laboratory,Children's Hospital of Chongqing University of Medical Sciences,Chongqing ,China"
            },
            {
                "name": "LIU Ai-bo",
                "org": "Key Laboratory of Child Development,Ministry of Education,Chongqing ,China"
            },
            {
                "name": "PU Yu",
                "org": "Key Laboratory of Pediatrics in Chongqing,Chongqing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Chongqing International Science and Technology Cooperation Center for Child Development and Disorders,Chongqing ,China"
            },
            {
                "name": "WU Wei-hua",
                "org": "Department of Pathogen Biology,Chongqing University of Medical Sciences,Chongqing ,China"
            },
            {
                "name": "YE Bin",
                "org": "Department of Pathogen Biology,Chongqing University of Medical Sciences,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2013
    },
    "vK5rgHwk": {
        "id": "vK5rgHwk",
        "title": "Application of Unified Power Flow Controller (UPFC) in Jiangsu power system",
        "abstract": "This paper presents applications of one operating 220 kV and the other constructing 500kV Unified Power Flow Controller (UPFC) projects in Jiangsu power system. The operating UPFC project in Nanjing Western Power Grid (NWPG) will be firstly introduced. Necessity and feasibility to utilise UPFC will be discussed. Capacity requirement and topology optimization of UPFC will be analyzed. Detailed parameters of the UPFC project will also be presented. After the description of real worked UPFC project, necessity and feasibility of the constructing 500kV UPFC project in Suzhou Southern Power Grid (SSPG) will be briefly talked. Huge economic and social benefits are obtained with the applications of UPFC.",
        "keywords": "",
        "authors": [
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Lin Yang",
                "org": "State Grid Jiangsu Electric Power Company, Nanjing, P.R. China"
            },
            {
                "name": "Haiqian Wang",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Pengcheng Song",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            }
        ],
        "venue": "power and energy society general meeting",
        "year": 2017
    },
    "wfW7GQaF": {
        "id": "wfW7GQaF",
        "title": "Oral health and risk of colorectal cancer: results from three cohort studies and a meta-analysis.",
        "abstract": "Data from three large prospective cohort studies and a meta-analysis did not support that oral health plays a major role in the development of colorectal cancer.While studies have shown that poor oral health status may increase the risk of cancer, evidence of a specific association with the risk of colorectal cancer (CRC) is inconclusive. We evaluated the association between oral health and CRC risk using data from three large cohorts: the Shanghai Men's Health Study (SMHS), the Shanghai Women's Health Study (SWHS), and the Southern Community Cohort Study (SCCS), and carried out a meta-analysis of results from other relevant published studies. This study applied a nested case-control study design and included 825 cases/3298 controls from the SMHS/SWHS and 238 cases/2258 controls from the SCCS. The association between oral health status (i.e. tooth loss/tooth decay) and CRC risk was assessed using conditional logistic regression models. A meta-analysis was carried out based on results from the present study and three published studies. We found that tooth loss was not associated with increased risk of CRC. ORs and respective 95% CIs associated with loss of 1-5, 6-10, and > 10 teeth compared with those with full teeth are 0.87 (0.69-1.10), 0.93 (0.70-1.24), and 0.85 (0.66-1.11) among SMHS/SWHS participants; and 1.13 (0.72-1.79), 0.87 (0.52-1.43), and 1.00 (0.63-1.58) for those with loss of 1-4, 5-10, and > 10 teeth among SCCS participants. Data regarding tooth decay were available in the SCCS, but were not associated with CRC risk. Meta-analysis confirmed the null association between tooth loss/periodontal disease and CRC risk (OR 1.05, 95% CI 0.86-1.29). In this analysis of three cohorts and a meta-analysis, we found no evidence supporting an association between oral health and CRC risk.",
        "keywords": [
            "oral health",
            "tooth loss",
            "tooth decay",
            "periodontal disease",
            "colorectal cancer risk"
        ],
        "authors": [
            {
                "name": "H G Ren",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "H N Luu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "H Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "Y B Xiang",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai, China"
            },
            {
                "name": "M Steinwandel",
                "org": "International Epidemiology Institute, Rockville"
            },
            {
                "name": "Y T Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong, University School of Medicine, Shanghai, China"
            },
            {
                "name": "M Hargreaves",
                "org": "Department of Internal Medicine, Meharry Medical College, Nashville, USA"
            },
            {
                "name": "W Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "W J Blot",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "J R Long",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            },
            {
                "name": "X O Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, USA"
            }
        ],
        "venue": "Annals of Oncology",
        "year": 2016
    },
    "U6om5HZG": {
        "id": "U6om5HZG",
        "title": "Foundation of the model of left ventricular remodeling in rat with pressure overload",
        "abstract": "Objective Heart failure is considered as one of fatal illnesses that threatens the lives of patients seriously.The aim of this study is to investigate the pathogenesis of heart failure.The establishment of an appropriate animal model is necessary for the research which is to simulate the physiopathologic change of left ventricular remodeling in congestive heart failure(CHF).Methods The rat model with pressure overload by abdominal aortic constriction was used.26 SD male rats were randomly divided into sham operation group and model group.It was observed after 4 and 8 weeks in the changes of myocardial hypertrophy(left ventricular mass index \\,left ventricular myocardium HE staining,left ventricular myocytes ultra microstructure),and myocardial fibrosis(left ventricular myocardium collagen pathological coloring,left ventricular interstitial cardiac tissue ultra microstructure).Results After 4 and 8 weeks,LVMI in model group was higher than that in sham operation group(P<0.01).Other abnormal changes of myocardial hypertrophy and myocardial fibrosis were also observed after 4 and 8 weeks.Conclusion After 4 weeks,the main physiopathologic changes of left ventricular remodeling were formed in the rat with pressure overload by abdominal aortic constriction,which was an appropriate model of left ventricular remodeling in CHF.",
        "keywords": [
            "Rat",
            "Myocardial fibrosis",
            "Myocardial hypertrophy",
            "Pressure overload",
            "Congestive heart failure",
            "Left ventricular remodeling"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2010
    },
    "x5pkZR7f": {
        "id": "x5pkZR7f",
        "title": "Fundamentals of lateral and vertical heterojunctions of atomically thin materials",
        "abstract": "At the turn of this century, Herbert Kroemer, the 2000 Nobel Prize winner in Physics, famously commented that “the interface is the device”. This statement has since opened up unparalleled opportunities at the interface of conventional three-dimensional (3D) materials (H. Kroemer, Quasi-Electric and Quasi-Magnetic Fields in Non-Uniform Semiconductors, RCA Rev., 1957, 18, 332–342). More than a decade later, Sir Andre Geim and Irina Grigorieva presented their views on 2D heterojunctions which further cultivated broad interests in the 2D materials field. Currently, advances in two-dimensional (2D) materials enable us to deposit layered materials that are only one or few unit-cells in thickness to construct sharp in-plane and out-of-plane interfaces between dissimilar materials, and to be able to fabricate novel devices using these cutting-edge techniques. The interface alone, which traditionally dominated overall device performance, thus has now become the device itself. Fueled by recent progress in atomically thin materials, we are now at the ultimate limit of interface physics, which brings to us new and exciting opportunities, with equally demanding challenges. This paper endeavors to provide stalwarts and newcomers a perspective on recent advances in synthesis, fundamentals, applications, and future prospects of a large variety of heterojunctions of atomically thin materials.",
        "keywords": "",
        "authors": [
            {
                "name": "Anupum Pant",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University,Tempe,USA"
            },
            {
                "name": "Zafer Mutlu",
                "org": "Materials Science and Engineering Program, Department of Mechanical Engineering, University of California,Riverside,USA"
            },
            {
                "name": "Darshana Wickramaratne",
                "org": "Materials Department, University of California,Santa Barbara,USA"
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University,Tempe,USA"
            },
            {
                "name": "Roger K. Lake",
                "org": ""
            },
            {
                "name": "Cengiz S. Ozkan",
                "org": "Materials Science and Engineering Program, Department of Mechanical Engineering, University of California,Riverside,USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University,Tempe,USA"
            }
        ],
        "venue": "Nanoscale",
        "year": 2016
    },
    "QXC0Rqta": {
        "id": "QXC0Rqta",
        "title": "Effects of captopril on the expression of myocardial α-myosin heavy chain and β-myosin heavy chain mRNA in rat with pressure overload",
        "abstract": "Objective To observe the effects of captopril on the expression of myocardial α-myosin heavy chain (α-MHC) and β-myosin heavy chain (β-MHC) mRNA in rat with pressure overload,and to explore the mechanism of the regression of left ventricular hypertrophy. Methods Thirty-six SD male rats were randomized into sham operation group,model group,and captopril group.The model rats were established by pressure overload.RT-PCR was used to detect the expression of α-MHC and β-MHC in myocardial tissues. Results The α-MHC mRNA expression in left ventricular myocardial tissue was lower in model group than that in sham operation group (P<0.05).The α-MHC mRNA expression in captopril group was higher than that in model group (P<0.05). The β-MHC mRNA expression of left ventricular myocardial tissue was higher in model group than that in sham operation group (P<0.05). The β-MHC mRNA expression was lower in captopril group than that in model group (P<0.05). Conclusion Captopril could increase the expression of α-MHC and decrease the expression of β-MHC,which may be one of mechanisms for regression of myocardial hypertrophy.",
        "keywords": [
            "β-MHC",
            "gene expression",
            "pressure overload",
            "captopril",
            "α-MHC",
            "myocardial hypertrophy"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Journal of Shanxi Medical University",
        "year": 2010
    },
    "FIL7iAA2": {
        "id": "FIL7iAA2",
        "title": "Fruit, vegetable, and animal food intake and breast cancer risk by hormone receptor status.",
        "abstract": "The effects of diet on breast cancer are controversial and whether the effects vary with hormone receptor status has not been well investigated. This study evaluated the associations of dietary factors with risk for breast cancer overall and by the hormone receptor status of tumors among Chinese women. The Shanghai Breast Cancer Study, a large, population-based, case-control study, enrolled 3,443 cases and 3,474 controls in 1996-1998 (phase I) and 2002-2005 (phase II); 2676 cases had estrogen receptor (ER) and progesterone receptor (PR) data. Dietary intake was assessed using a validated, quantitative, food frequency questionnaire. Odds ratios (OR) and 95% confidence intervals (95% CI) were derived from multivariate, polychotomous, unconditional logistic regression models. Total vegetable intake was inversely related to breast cancer risk, with an adjusted OR for the highest quintile of 0.80 (95% CI = 0.67-0.95; P trend = 0.02). Reduced risk was also related to high intake of allium vegetables (P trend = 0.01) and fresh legumes (P trend = 0.0008). High intake of citrus fruits and rosaceae fruits were inversely associated with breast cancer risk (P trend = 0.003 and 0.004, respectively), although no consistent association was seen for total fruit intake. Elevated risk was observed for all types of meat and fish intake (all P trend < 0.05), whereas intakes of eggs and milk were associated with a decreased risk of breast cancer (both P trend <0.05). There was little evidence that associations with dietary intakes varied across the 4 tumor subtypes or between ER+/PR+ and ER-/PR- tumors (P for heterogeneity >0.05). Our results suggest that high intake of total vegetables, certain fruits, milk, and eggs may reduce the risk of breast cancer, whereas high consumption of animal-source foods may increase risk. The dietary associations did not appear to vary by ER/PR status.",
        "keywords": [
            "estrogen receptor",
            "logistic regression model",
            "odd ratio",
            "case control study",
            "progesterone receptor",
            "breast cancer",
            "confidence interval"
        ],
        "authors": [
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Zhi-Xian Ruan",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Yinghao Su",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            }
        ],
        "venue": "Nutrition and cancer",
        "year": 2012
    },
    "bcJIUQm5": {
        "id": "bcJIUQm5",
        "title": "Abstract LB-412: Urinary polyphenols, GST copy number variation, and breast cancer risk: Results from the Shanghai Women's Health Study (SWHS)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "guoliang li",
                "org": ""
            },
            {
                "name": "nathaniel rothman",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "jianfeng luo",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "wongho chow",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "qi dai",
                "org": ""
            },
            {
                "name": "adrian a franke",
                "org": ""
            },
            {
                "name": "martha j shrubsole",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "wlQMTGpH": {
        "id": "wlQMTGpH",
        "title": "Effect of Acupuncture on AdipoR mRNA Expression of Aorta in Hyperlipidemia Rats",
        "abstract": "Objective To study the effect of acupuncture on adiponectin receptor(AdipoR)expressions of aorta in hyperlipidemia rats.Methods Rat models were established with high-fat feed for 12 week.All rats were randomly divided into model group and acupuncture group based on the body weight.The levels of serum lipid,nitric oxide(NO)and myeloperoxidase(MPO) were measured,and the aortal mRNA expressions of adipoR1 and adipoR2 were detected with real time RT-PCR after 4 weeks treatment.And rats with normal forage were as controls.Results Compared with the controls,serum levels of triglyceride(TG),total cholesterol(TC)and MPO were increased obviously and the NO content was decreased markedly in both model and acupuncture groups pre-treatment.after treatment for 4 weeks,there were no changes in the levels of serum TG,TC,MPO and NO.The aortal mRNA expressions of AdipoR1 and AdipoR2 were depressed obviously in model group.Compared to the model,the levels of serum TG,TC and MPO in acupuncture group were decreased significantly.Serum NO content and aortal AdipoR2 mRNA expression were increased markedly.Conclusion Depressed aortal mRNA expressions of AdipoR1 and AdipoR2 due to high-fat dietary could affect the protective function of adiponectin signal on aorta.Acupuncture could upregulate adiponectin signal and protect aorta from damage induced by high-fat dietary,which could be mediated primarily by AdipoR2.",
        "keywords": [
            "acupuncture",
            "mRNA expression",
            "adiponectin receptor",
            "high-fat dietary"
        ],
        "authors": [
            {
                "name": "Yuan Aihong",
                "org": " Nanjing General Hospital of Nanjing Military Command%%#Nanjing %%#"
            },
            {
                "name": "Cai Hui",
                "org": " Nanjing General Hospital of Nanjing Military Command%%#Nanjing %%#"
            }
        ],
        "venue": "Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease",
        "year": 2010
    },
    "DGgVKFY3": {
        "id": "DGgVKFY3",
        "title": "The research development of the citrullinated protein in rheumatoid arthritis",
        "abstract": "At present,it is known that the Citrullinated Protein is one of the most important target antigens in rheumatoid arthritis' pathomechanism.Anti-cyclic citrullinated peptide(anti-CCP) antibody is the new specific antibody in the early diagnosis of the rheumatoid arthritis,in future.This article mainly given an account of the research development of the Citrullinated Protein in rheumatoid arthritis.",
        "keywords": [
            "Citrullinated protein",
            "Rheumatoid arthritis",
            "Pathomechanism",
            "Target antigens",
            "Early diagnosis"
        ],
        "authors": [
            {
                "name": "GAO Peifang",
                "org": ",et al.Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "YAO Rubing",
                "org": ",et al.Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ",et al.Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Osteoporosis",
        "year": 2010
    },
    "6dSV9Hao": {
        "id": "6dSV9Hao",
        "title": "Associations of dietary intake and supplement use with post-therapy cognitive recovery in breast cancer survivors.",
        "abstract": "Our results indicate that higher vegetable intake, tea drinking, and fish oil supplementation may help post-therapy cognitive recovery for cancer patients.",
        "keywords": [
            "Breast cancer survivor",
            "Cognition",
            "Diet",
            "Supplement"
        ],
        "authors": [
            {
                "name": "Zhezhou Huang",
                "org": "Division of Non-communicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, 200336, Shanghai, China."
            },
            {
                "name": "Yan Shi",
                "org": "Division of Non-communicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, 200336, Shanghai, China. shiyan@scdc.sh.cn."
            },
            {
                "name": "Pingping Bao",
                "org": "Division of Non-communicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, 1380 Zhongshan West Road, 200336, Shanghai, China."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203-1738, USA."
            },
            {
                "name": "Zhen Hong",
                "org": "Department of Neurology, Huashan Hospital, Fudan University, 200040, Shanghai, China."
            },
            {
                "name": "Ding Ding",
                "org": "Department of Neurology, Huashan Hospital, Fudan University, 200040, Shanghai, China."
            },
            {
                "name": "James Jackson",
                "org": "Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203-1738, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203-1738, USA."
            },
            {
                "name": "Qi Dai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, 37203-1738, USA."
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2018
    },
    "4SaJcgCC": {
        "id": "4SaJcgCC",
        "title": "Soy Food Intake and Circulating Levels of Inflammatory Markers in Chinese Women",
        "abstract": "Background: Soy and some of its constituents, such as isoflavones, have been shown to affect the inflammatory process in animal studies. The association between soy food intake and inflammatory markers has not been evaluated adequately in humans. Objective: Our aim was to evaluate whether higher intake of soy foods was inversely associated with inflammatory markers in 1,005 middle-aged Chinese women. Design: In this cross-sectional study, dietary intake of soy foods was assessed by a validated food frequency questionnaire and by a 24-hour recall when biospecimens were procured. A general linear model was used to estimate the geometric means of selected inflammatory markers, including interleukin-6 (IL-6), IL-1β, tumor necrosis factor-α (TNFα), soluble IL-6 receptor, soluble GP130, soluble TNF receptors 1 and 2, and C-reactive protein, across categories of soy food intake after adjusting for age, lifestyle and dietary factors, and history of infectious or inflammation-related diseases. Results: We found that multivariable-adjusted geometric mean concentrations of IL-6 and TNFα were inversely associated with quintiles of soy food intake, with a difference between the highest and lowest quintiles of 25.5% for IL-6 (P for trend=0.008) and 14% for TNFα (P for trend=0.04). Similar inverse associations were found for TNFα (P for trend =0.003), soluble TNF receptor 1 (P for trend=0.01), soluble TNF receptor 2 (P for trend=0.02), IL-1β (P for trend=0.05), and IL-6 (P for trend=0.04) when soy food consumption was assessed by the frequency of consumption in the preceding 24 hours. No significant associations were found for other markers studied. Conclusions: This study suggests that soy food consumption is related to lower circulating levels of IL-6, TNFα, and soluble TNF receptors 1 and 2 in Chinese women. © 2012 Academy of Nutrition and Dietetics.",
        "keywords": [
            "Soy",
            "Inflammation",
            "Interleukin-1β",
            "Interleukin-6",
            "Tumor necrosis factor-α"
        ],
        "authors": [
            {
                "name": "Sheng Hui Wu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Wongho Chow -",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Xianglan Zhang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Yutang Gao -",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Gong Yang",
                "org": "Address correspondence to: Gong Yang, MD, MPH, Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, 2525 West End Ave, Suite 600 (IMPH), Nashville, TN 37203-1738"
            }
        ],
        "venue": "Journal of the Academy of Nutrition and Dietetics",
        "year": 2012
    },
    "2E4U7QfM": {
        "id": "2E4U7QfM",
        "title": "Effect of curcumin on angiogenesis and hypoxia-inducible factor 1-α expression in synovium of adjuvant arthritis rats",
        "abstract": "Objective To explore the effect of curcumin on angiogenesis and hypoxia-inducible factor 1-α(HIF-1α) expression in synovium of adjuvant arthritis rats for the mechanism of curcumin treatment of rheumatoid arthritis.Methods Forty SD rats were divided into normal control group,model group,curcumin group and methotrexat group,modeling with complete Freund adjuvant.The rats of curcumin group were treated with curcumin intraperitoneal injection 50 mg·kg-1·d-1 continuously for 14 days and rats of methotrexat group were treated with methotrexat intraperitoneal injection 0.5 mg·kg-1·3 d-1 for 5 times.Synovium micro vessels density(MVD) were observed and the expression of HIF-1α was detected by immunohistochemical test.Results ①In model group,MVD(11.10±1.50) scores and HIF-1α(1.50±0.33) scores showed higher expression than normal control group(P<0.01);②After treatment,immunohistochemical test showed that the expression of MVD,HIF-1α all had significant difference compared curcumin group MVD(8.80±1.14) scores,HIF-1α(0.80±0.26) scores and methotrexat group MVD(8.73±1.15) scores,HIF-1α(0.85±0.34) scores to model group(P<0.01),and the difference between curcumin group and methotrexat group were not significant(P>0.05).Conclusion Curcumin can inhibit HIF1-α expression in the synovium,and reduce MVD.It might be one of the machanisms of curcumin curing rheumatoid arthritis.",
        "keywords": [
            "angiogenesis inhibitors",
            "arthritis",
            "experimental",
            "aryl hydrocarbon receptor nuclear translocator"
        ],
        "authors": [
            {
                "name": "SHANG Wei",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Peng",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Clinical Focus",
        "year": 2012
    },
    "jPUDd0ge": {
        "id": "jPUDd0ge",
        "title": "Abstract 119: Urinary biomarkers of oxidative stress and breast cancer survival among Chinese breast cancer survivors.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ying zheng",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "sarah nechuta",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "wei lu",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "qi dai",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "ginger l milne",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "zeU2XZDD": {
        "id": "zeU2XZDD",
        "title": "Intra-individual variation of miRNA expression levels in human plasma samples.",
        "abstract": "Background: Circulating miRNAs as potential non-invasive biomarkers for disease risk assessment and cancer early diagnosis have attracted increasing interest. Little information, however, is available regarding the intra-individual variation of circulating miRNA levels.Methods: We measured expression levels of a panel of 800 miRNAs in repeated plasma samples from 51 healthy individuals that were collected 6 to 12months apart and evaluated the intra-individual variation by the intra-class correlation coefficient (ICC).Results: After background correction, a total of 185 miRNAs were detected in at least 10% of the plasma samples, with 69 and 28 miRNAs being detected in 50% and 90% of samples, respectively. The median ICC was 0.46 for these 185 miRNAs. Among them, 41% (75 miRNAs) had an ICC0.5, and 23% (42 miRNAs) had an ICC0.6. The ICC is higher for miRNAs with higher expression levels or higher detection rates, when compared to those with lower expression levels or lower detection rates.Conclusions: These results suggest that common circulating miRNAs are stable over a relatively long period and can serve as reliable biomarkers for epidemiological and clinical research.",
        "keywords": [
            "Circulating miRNA",
            "intra-individual variation",
            "intra-class correlation coefficient",
            "biomarkers",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "Jie Wu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37235 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37235 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Charles E Matthews",
                "org": "NCI, Div Canc Epidemiol & Genet, Metab Epidemiol Branch, Bethesda, MD 20892 USA"
            },
            {
                "name": "Fei Ye",
                "org": "Vanderbilt Univ, Sch Med, Dept Biostat, Nashville, TN 37235 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37235 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37235 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37235 USA"
            }
        ],
        "venue": "BIOMARKERS",
        "year": 2018
    },
    "fJ5OppqW": {
        "id": "fJ5OppqW",
        "title": "0346 Occupational Exposure to Lead and Cancer in Two Cohort Studies of Men and Women in Shanghai, China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "linda m liao",
                "org": "national cancer institute"
            },
            {
                "name": "m c friesen",
                "org": "national cancer institute"
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "donghee koh",
                "org": ""
            },
            {
                "name": "butian ji",
                "org": "national cancer institute"
            },
            {
                "name": "g yang",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "s j locke",
                "org": "national cancer institute"
            },
            {
                "name": "nathaniel rothman",
                "org": "national cancer institute"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "mark p purdue",
                "org": "national cancer institute"
            }
        ],
        "venue": "Occupational and Environmental Medicine",
        "year": 2014
    },
    "0B8ondig": {
        "id": "0B8ondig",
        "title": "Effects of Captopril on Left Ventricular Myocardial Tissue Local Angiotensin Ⅱ in Rat with Pressure Overload",
        "abstract": "Objective:To observe the effects of captopril on level of left ventricular myocardial tissue local angiotensin Ⅱ in rat with pressure overload and study the possible mechanism of regressing left ventricular remodeling. Method:Calculated left ventricular mass index by a validated formula:left ventricular mass index = left ventricular mass/body weight,light microscope and electron microscope were used to observe the left ventricular myocardium histopathological hematoxylin and eosin (H&E) staining and left ventricular myocytes ultramicrostructure respectively,radioimmunoassay was used to detect left ventricular myocardial tissue local angiotensin Ⅱ(AngⅡ).Results:The LVMI and AngⅡ level of left ventricular myocardial tissue in model group were higher than that of sham operation group (P<0.01). In captopril group,the LVMI and AngⅡ level were lower than that in model group(P<0.01). Under light microscope,HE staining of cardiac muscle in sham group:the size and form were normal,the fibers lined up in order,while there were great different in model group:the diameter of cardiac cells were increased; the fibers of interstitial tissue were in a great mess. HE staining of captopril was same to those of sham group. The left ventricular myocytes ultramicrostructure of sham group were eumorphism,while there were great different in model group:the chondrosome appear to degeneration,such as crista mitochondriales decreased,fracture,the density of stroma is thinner,sarcoplasmic reticulum is expanding; myofibrillar degeneration such as:the myofibril break,confused,the brink of cell nucleus irregularity,chromatin move to verge. The left ventricular myocytes ultramicrostructure of captopril were similar to that of sham group. Conclusion:Captopril had effects on regressing left ventricular remodeling which maybe concerned with the decrease of left ventricular myocardial tissue local AngⅡ level.",
        "keywords": [
            "Rat",
            "Tissue angiotensin Ⅱ",
            "Pressure overload",
            "Left ventricular remodeling"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et al/Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing "
            },
            {
                "name": "Zhang Qunyan",
                "org": ",et al/Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing "
            },
            {
                "name": "Dong Xiaolei",
                "org": ",et al/Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2011
    },
    "z5VH9Zrr": {
        "id": "z5VH9Zrr",
        "title": "Influence of acupuncture on expression of aorta Adipo R 1 and 2 in hyperlipaemia rats",
        "abstract": "[Objective] To explore the influence of high fat diet on aorta adiponectin signal and the regulatory effect of acupuncture on it in SD rats.[Methods] The SD rats were fed with high fat diet for 12 weeks in just delactated rats and then measured the blood lipid,MPO and NO.The rats were randomly divided into model group and acupuncture group according to the body weight.After intervention for 4 weeks serum APN was detected with ELISA and the expression of Adipo R 1 and 2 with Western blotting method.The rats feeding with common food were served as control.[Results] The levels of TG,TC,MPO were obviously increased and NO obviously decreased after feeding high fat diet for 12 weeks in SD rats.After intervention for 4 weeks,the serum adiponectin,protein content of Adipo R 1 and 2 of model group were distinctly lower than control group.The content of serum adiponectin and aorta Adipo R 2 were obviously increased,the level of Adipo R 1 had a rising tendency.[Conclusion] The hyperlipaemia rats feeding by high fat diet showed signal transduction disorder of aorta adiponectin.Acupuncture can regulate it by increasing serum APN and the level of aorta Adipo R 2.The Adipo R 2 plays a crucial role.",
        "keywords": [
            "acupuncture",
            "adiponectin receptor",
            "hyperlipaemia",
            "aorta"
        ],
        "authors": [
            {
                "name": "YUAN Ai-hong",
                "org": "Dept.of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Dept.of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Tianjin Journal of Traditional Chinese Medicine",
        "year": 2011
    },
    "Y0Y3hx4m": {
        "id": "Y0Y3hx4m",
        "title": "Associations of leukocyte telomere length with body anthropometric indices and weight change in chinese women: Associations of Leukocyte Telomere Length",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "yong cui",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "s qu",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "jie wu",
                "org": ""
            },
            {
                "name": "butian ji",
                "org": ""
            },
            {
                "name": "wongho chow",
                "org": ""
            }
        ],
        "venue": "Obesity",
        "year": 2013
    },
    "v8UlY1kA": {
        "id": "v8UlY1kA",
        "title": "Vegetable-based dietary pattern and liver cancer risk: results from the Shanghai women's and men's health studies.",
        "abstract": "Although dietary patterns, specific foods, and their constituents have been linked to cancer risk, the role of dietary patterns and specific food groups in liver cancer risk has not been investigated. In the Shanghai Women's Health Study (SWHS) and Shanghai Men's Health Study (SMHS), two cohort studies of 132837 Chinese women and men, we evaluated the relationship between dietary patterns, food groups, and liver cancer risk. Through in-person interviews, dietary information intake over the preceding year was collected by using a validated food-frequency questionnaire. Cox regression model was used to estimate hazard ratios and 95% confidence intervals with adjustment for potential confounders. During an average follow-up of 10.9 (SWHS) or 5.5 (SMHS) years, 267 incident liver cancer cases were identified after the first 2years of study enrolment. Three dietary patterns were derived by factor analysis. A vegetable-based dietary pattern was inversely associated with liver cancer; hazard ratios (95% confidence intervals) for the lowest to highest quartiles were: 1.00; 0.98 (0.71-1.35); 0.93 (0.67-1.29); and 0.58 (0.40-0.84); P-trend=0.01. The association was stronger among participants with a history of chronic liver disease. Further analyses showed high intakes of celery, mushrooms, allium vegetables, composite vegetables (including asparagus lettuce and garland chrysanthemum), legumes and legume products were associated with reduced liver cancer risk (all P-trend<0.05). Fruit- and meat-based dietary patterns were not associated with liver cancer risk. Our study suggests that a vegetable-based dietary pattern is associated with reduced liver cancer risk.",
        "keywords": [
            "prospective studies",
            "china",
            "risk factors",
            "risk",
            "proportional hazards models"
        ],
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, State Key Lab Oncogene & Related Genes,Renji Hosp, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, State Key Lab Oncogene & Related Genes,Renji Hosp, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, State Key Lab Oncogene & Related Genes,Renji Hosp, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr,Vanderbilt Ingr, Nashville, TN 37212 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr,Vanderbilt Ingr, Nashville, TN 37212 USA"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, Rockville, MD USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, Dept Epidemiol,Renji Hosp, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr,Vanderbilt Ingr, Nashville, TN 37212 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr,Vanderbilt Ingr, Nashville, TN 37212 USA"
            }
        ],
        "venue": "CANCER SCIENCE",
        "year": 2013
    },
    "QPz9qupQ": {
        "id": "QPz9qupQ",
        "title": "Physical activity and the incidence of type 2 diabetes in the Shanghai women's health study.",
        "abstract": "Leisure-time physical activity (LPA) has been associated with a reduced risk of type 2 diabetes. However, the potential effect of other types of physical activity on type 2 diabetes is still uncertain. The aim of this study was to examine the effect of occupational, commuting, daily living, and LPA on the incidence of type 2 diabetes in a cohort of middle-aged women.We prospectively followed 70,658 women who had no prior history of diabetes at study recruitment for 4.6 years. Participants completed in-person interviews at baseline that collected information on diabetes risk factors including physical activity habits. Anthropometric measurements were taken by trained interviewers. Multivariate-adjusted hazard ratios were estimated by levels of occupational, commuting, daily living, and LPA.We documented 1973 incident cases of diabetes during 326,625 person-years of follow-up. LPA and daily living physical activity (DPA) were associated with a moderately reduced risk of type 2 diabetes. The relative risk for type 2 diabetes associated with LPA and DPA categories were 1.00, 0.89, 1.05, and 0.83, (P trend = 0.12) and 1.00, 0.98, 0.95, and 0.88, (P trend = 0.06) respectively. LPA was associated with lower risk of type 2 diabetes in employed participants (P trend = 0.09) while DPA was mainly associated with a reduction in risk in non-employed participants (P trend <0.01). While occupational physical activity was not associated with type 2 diabetes risk in this population, commuting to work was associated with a reduction in risk. A combination of DPA and LPA was associated with a reduced risk of type 2 diabetes.This study suggests that physical activity, either from leisure-time exercise or daily activity reduces the risk of type 2 diabetes in women, supporting the current health promotion efforts encouraging both exercise and non-exercise activity levels.",
        "keywords": [
            "occupational",
            "daily living leisure",
            "commuting physical activity",
            "type 2 diabetes",
            "relative risk",
            "fitness",
            "population",
            "physical activity",
            "research methodology",
            "incidence",
            "health",
            "measurement",
            "prospective studies",
            "behavior",
            "developing countries",
            "diabetes",
            "health promotion"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Charles E Matthews",
                "org": ""
            },
            {
                "name": "Michael Leitzmann",
                "org": ""
            },
            {
                "name": "Qi Li",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology|Shanghai Cancer Institute"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine|Center Vanderbilt - Ingram Cancer Center|Vanderbilt University|School of Medicine"
            }
        ],
        "venue": "International journal of epidemiology",
        "year": 2006
    },
    "1i1DwVRH": {
        "id": "1i1DwVRH",
        "title": "Erratum to: Urinary polyphenols and breast cancer risk: results from the Shanghai Women’s Health Study",
        "abstract": "",
        "keywords": [
            "breast cancer"
        ],
        "authors": [
            {
                "name": "Jianfeng Luo",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "Department of Health and Human Services Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH Bethesda MD USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "Department of Health and Human Services Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH Bethesda MD USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Martha J. Shrubsole",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Adrian A. Franke",
                "org": "University of Hawaii Cancer Research Center of Hawaii 1236 Lauhala Street Honolulu HI 96813 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            }
        ],
        "venue": "Breast Cancer Research and Treatment",
        "year": 2010
    },
    "YWXTjaKL": {
        "id": "YWXTjaKL",
        "title": "Nephrolithiasis among middle aged and elderly urban Chinese: A report from prospective cohort studies in Shanghai.",
        "abstract": "Introduction: Kidney stone risk factors are understudied among Asians. Our study objective was to investigate associations of obesity and other chronic diseases with incident kidney stones among the urban Chinese. Patients and Methods: Included in this study are two prospective cohorts: the Shanghai Women's Health Study (N=69,166) and Shanghai Men's Health Study (N=58,054). Incident kidney stones were determined by self-report in 2004 and 2008. Cox regression models were used to evaluate the associations of study variables with stone risk with adjustment of demographics, medical history, and dietary intakes. Results: There were 2653 incident stones over 1,007,958 person-years of follow-up. Overall incidence rates (per 1000 person-years, 95% confidence interval [CI]) were 2.10 (1.99, 2.21) among women and 3.80 (3.59, 4.02) among men. Higher body mass index (BMI) was associated with risk (BMI 25 vs 18.5-24.9kg/m(2), women: hazard ratio [HR]=1.14 [95% CI 1.01, 1.28]; men: HR=1.17 [1.03, 1.32]). High waist-hip ratio (0.80 and 0.90 for women and men, respectively) was associated with risk (HR 1.13, 95% CI 1.01, 1.27 for women; HR 1.19, 95% CI 1.05, 1.35 for men). Coronary heart disease or stroke history was associated with risk in women only (HR 1.31, 95% CI 1.10, 1.56). Hypertension history was associated with risk in men only (HR 1.27, 95% CI 1.11, 1.45). No significant association with diabetes mellitus was observed. Conclusions: Among the Chinese, kidney stone incidence in men is almost twice that of women. Obesity is a shared risk factor. Hypertension history is associated with risk in men, whereas history of coronary heart disease or stroke is associated with risk in women.",
        "keywords": [
            "kidney calculi",
            "diet",
            "adult",
            "risk factors",
            "prospective studies"
        ],
        "authors": [
            {
                "name": "Xiang Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, SKLORG, Shanghai, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, SKLORG, Shanghai, Peoples R China"
            },
            {
                "name": "Loren Lipworth",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA"
            },
            {
                "name": "Nicole L Miller",
                "org": "Vanderbilt Univ, Med Ctr, Dept Urol Surg, 1161 21st Ave South,A-1302 Med Ctr North, Nashville, TN 37232 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN 37232 USA"
            },
            {
                "name": "Ryan S Hsi",
                "org": "Vanderbilt Univ, Med Ctr, Dept Urol Surg, 1161 21st Ave South,A-1302 Med Ctr North, Nashville, TN 37232 USA"
            }
        ],
        "venue": "JOURNAL OF ENDOUROLOGY",
        "year": 2017
    },
    "TR4HsapW": {
        "id": "TR4HsapW",
        "title": "Abstract 3265: Dual specificity phosphatase 4 gene expression in triple negative breast cancer",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "michelle l baglia",
                "org": "vanderbilt university"
            },
            {
                "name": "qiuyin cai",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "jie wu",
                "org": "vanderbilt university"
            },
            {
                "name": "yinghao su",
                "org": "vanderbilt university"
            },
            {
                "name": "fei ye",
                "org": "vanderbilt university"
            },
            {
                "name": "pingping bao",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "zhiguo zhao",
                "org": "vanderbilt university"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "wei lu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "20RUd3kA": {
        "id": "20RUd3kA",
        "title": "Effects of total flavonoids of epimedium on matrix metall-oproteinase-2,-9 expression in myocardium of a rat model of congestive heart failure induced by isoproterenol",
        "abstract": "Objective To investigate the effects of total flavonoids of epimedium (TFE) on mRNA expression and activities of metalloproteinase-2(MMP-2),MMP-9 in myocardium of a rat model of congestive heart failure (CHF) induced by isoproterenol.Methods CHF was induced in male Sprague-Dawley rat model was established using subcutaneous injection of isoproterenol.Rat models of CHF were randomized into model group (n = 15),metoprolol group (n = 12),TFE-low-dose group(n = 11),TFE-medium-dose group(n = 10) and TFE-high-dose group(n = 12).Rats injected with saline were used as normal cotrols(n = 10).Left ventricular weight index (LVWI) and haemodynamic parameters of rat hears in each group were detected.MMP-2,MMP-9 mRNA expression in rat myocardium was determined by RT-PCR and real-time PCR,MMP-2,MMP-9 activities were examined by gelatin zymography assay.Results Compared with model group of CHF,TFE could dose-dependently rescure the diversities of LVWI and hemodynamic parameters(P < 0.05 or < 0.01).In addition,TFE could also significantly down-regulated MMP-2,MMP-9 mRNA expression (P < 0.05 or 0.01) and suppressed activities of MMP-2 and MMP-9.Conclusion TFE can suppress mRNA expression and activities of MMP-2,MMP-9 in myocardium of a rat model of CHF induced by isoproterenol.This indicates that TFE may has a protective role of preventing myocardial remodeling associated with CHF.",
        "keywords": [
            "Total flavonoids of epimedium",
            "Heart failure",
            "Metalloproteinase-2",
            "Metalloproteinase-9"
        ],
        "authors": [
            {
                "name": "WANG Jing",
                "org": ". Department of Cardiovascular Disease.Nanjing Red Cross Hospital,Nanjing ,China"
            },
            {
                "name": "SONG Yao-hong",
                "org": ". Department of Cardiovascular Disease.Nanjing Red Cross Hospital,Nanjing ,China"
            },
            {
                "name": "LI Bao-shi",
                "org": ". Department of Cardiovascular Disease.Nanjing Red Cross Hospital,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ". Department of Cardiovascular Disease.Nanjing Red Cross Hospital,Nanjing ,China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2010
    },
    "xdjKpZB5": {
        "id": "xdjKpZB5",
        "title": "Changes of cardiac cyclic nucleotides in rats with isoproterenol-induced chronic heart failure",
        "abstract": "Objective To establish a murine model of isoproterenol(ISO)-induced chronic heart failure(CHF)and explore the relation between the changes of cardiac cyclic nucleotides and the activation of cytokines in the neuroendocrine system.Methods The rat model was constructed with two subcutaneous injections of ISO at a dose of 170 mg per kilogram body weight.At week 18,left ventricular ejection fraction(LVEF),fractional shortening(FS),left ventricular end diastolic diameter(LVEDD),and left ventricular end systolic diameter(LVESD)were assessed by echocardiogram.Plasma levels of norepinephrine(NE)and TNF-α and contents of NO,cAMP,and cGMP in the myocardial homogenate were detected.The pathomorphological features of the myocardium were observed.Results As compared with the normal control group,LVEF and FS were markedly decreased;LVEDD and LVESD were enlarged;the ratio of left ventricular weigh to body weigh,levels of NE and TNF-α,NO content,and the cAMP /cGMP ratio were significantly increased in the model group;however,contents of cAMP and cGMP were evidently declined(P < 0.01 for all comparisons).Conclusions Isoproterenol induces chronic heart failure in rats.The cytokines in the neuroendocrine system are activated and the contents of cAMP and cGMP are declined but with an elevated ratio of cAMP /cGMP in those rats.",
        "keywords": [
            "Heart failure",
            "congestive Isoproterenol Neurosecretory systems Cytokines Nucleotides Rats"
        ],
        "authors": [
            {
                "name": "CHEN Xiang-min",
                "org": ".Nanjing General Hospital,Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".Nanjing General Hospital,Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": ".Nanjing General Hospital,Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Nanjing General Hospital,Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2008
    },
    "7Kt38JZi": {
        "id": "7Kt38JZi",
        "title": "Associations of leukocyte telomere length with body anthropometric indices and weight change in Chinese women.",
        "abstract": "This study evaluated associations of telomere length with various anthropometric indices of general and abdominal obesity, as well as weight change.The study included 2,912 Chinese women aged 40-70 years. Monochrome multiplex quantitative polymerase chain reaction was applied to measure relative telomere length.Telomere length was inversely associated with body mass index (BMI), waist circumference, waist-to-height ratio, weight, and hip circumference (Ptrend = 0.005, 0.004, 0.004, 0.010, and 0.026, respectively), but not waist-to-hip ratio (Ptrend = 0.116) or height (Ptrend = 0.675). Weight change since age 50 was further evaluated among women over age 55. Women who maintained their weight within ±5% since age 50, particularly within a normal range (BMI = 18.5-24.9 kg/m(2) ), or reduced their weight from overweight (BMI = 25-29.9 kg/m(2) ) or obesity (BMI ≥30 kg/m(2) ) to normal range, had a longer mean of current telomere length than women who gained weight since age 50 (Ptrend = 0.025), particularly those who stayed in obesity or gained weight from normal range or overweight to obesity (P = 0.023).Our findings show that telomere shortening is associated with obesity and that maintaining body weight within a normal range helps maintain telomere length.",
        "keywords": [],
        "authors": [
            {
                "name": "Yong Cui",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Shimian Qu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Jie Wu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Gong Yang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            }
        ],
        "venue": "Obesity (Silver Spring, Md.)",
        "year": 2013
    },
    "NPEfw91F": {
        "id": "NPEfw91F",
        "title": "Effect of Total Flavonoids of Epimedium on Blood Lipid in Hyperlipidemia Rat",
        "abstract": "Objective To investigate the effect of total flavonoids of epimedium(TFE) on total cholesterol(TC),triglyeride(TG),high density lipoprotein cholesterol(HDL-C) and low density lipoprotein cholesterol(LDL-C) in blood plasm of hyperlipidemia rats.Methods 40 male SD rats were randomly devided into the high-fat diet group(31) and the full diet group(9).High fat diet group were fed with high-fat diet(HF) for 12 weeks,then the blood lipid were detected,which indicated that 26 of them had established the model of hyperlipidemia rat.Then the 26 male SD rats were randomly devided into three groups:the hyperlipidemia group(8),hyperlipidemia group with a large dose of TFE(9,lavaged with TFE 200 mg,1 d-1,for 4 weeks),and hyperlipidemia group with a small dose of TFE(9,lavaged with TFE 100 mg,1 d-1,for 4 weeks).At the 16th week,respectively,serum lipid level was measured in the rats.Results Compared with the full diet group,the levels of TG,TC,LDL-C in high-fat diet group were significantly increased(all P<0.01) before intervention,while the level of HDL-C has no statistical significance(P>0.05).The levels of TG and TC in hyperlipidemia group were higher than the full diet group(both P<0.01) after intervention.Compared with the hyperlipidemia group,both of the levels of TC and TG in hyperlipidemia group with large dose of TFE and small dose of TFE were obviously lower(P<0.05 or 0.01),while the levels of LDL-C and HDL-C has no statistical significance(P>0.05).Conclusion TFE can reduce the levels of TC and TG in hyperlipidemia rats.",
        "keywords": [
            "animals",
            "total flavonoids of epimedium",
            "laboratory",
            "rats",
            "hyperlipidemia rats",
            "blood lipid"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "XU Jia-yang",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Journal of Nanchang University(Medical Science)",
        "year": 2010
    },
    "lxBwwgLf": {
        "id": "lxBwwgLf",
        "title": "The effect of panax notoginseng saponins on interferon-γ and interleukin-4 secreted by cyclic citrullinated peptide antigen special T cell of rheumatoid arthritis",
        "abstract": "Objective It had been reported that panax notoginseng saponins(PNS)was effective on treating rheumatoid arthritis(RA).Cyclic citrullinated peptide(CCP)antigen,as target antigens,is on intimate terms with pathogenesy of RA.To study the effect of PNS on interferon-γ and interleukin-4 secreted by of CCP-AST RA.Methods Peripheral blood lymphocyte(PBL) from 24 RA patients were divided into four groups and cultured respectively in vitro.RA blank control group:PBL of RA patients were cultured and not interfered by drug;RA CCP group:PBL of RA patients were interfered by CCP(degree of enrichment 20 μg/ml);RA Methotrexate(MTX)control group:PBL of RA patients were interfered by CCP and MTX(each degree of enrichment 20 μg/ml);RA PNS group:PBL of RA patients were interfered by CCP and PNS(each degree of enrichment 20 μg/ml).After cultured respectively in vitro for 72h,the concentration of INF-γ and IL-4 were measured by ELISA.Results Compared with the concentration of INF-γ and IL-4 from RA blank control group,T cell of CCP group peripheral blood secreted more INF-γ(P<0.05),lower IL-4(P<0.05),and IFN-γ/IL-4 were up-regulated(P<0.01).Compared with the concentration of INF-γ and IL-4 from RA CCP group,T cell of RA PNS group secreted lower INF-γ(P<0.05),more IL-4(P<0.05).Conclusion PNS can inhibit secretion of TH1 cytokines INF-γ,and promote secretion of TH2 cytokines IL-4.PNS may have effect on disequilibrium of TH1/TH2,which may have important effect on treatment of RA.",
        "keywords": [
            "T cell",
            "Rheumatoid arthritis",
            "Interleukin-4",
            "Panax notoginseng saponins",
            "Cyclic citrullinated peptide",
            "Interferon-γ"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2010
    },
    "9O3DoQVH": {
        "id": "9O3DoQVH",
        "title": "Abstract 3011: Dietary fat, fatty acids, and ovarian cancer risk: Preliminary findings from the Shanghai Women’s Health Study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Eftitan Y. Akam",
                "org": ""
            },
            {
                "name": "Harvey J. Murff",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Nikhil K. Khankari",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Xiao O. Shu",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Alicia Beeghly-Fadiel",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2017
    },
    "ivUcCuZO": {
        "id": "ivUcCuZO",
        "title": "Development Process of Waste Leachate Treatment Technology in China",
        "abstract": "Taking representativeness projects as typical cases, the development process of waste leachate treatment technology in China, and reply measures that should be taken to adapt to new pollution-control standard were introduced.",
        "keywords": [
            "waste leachate",
            "pollution-control standard",
            "membrane bioreactor"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": "China Urban Construction Design & Research Institute, Beijing "
            },
            {
                "name": "Xiong Xiangyang",
                "org": "China Urban Construction Design & Research Institute, Beijing "
            }
        ],
        "venue": "Environmental Sanitation Engineering",
        "year": 2010
    },
    "TAN2kSC8": {
        "id": "TAN2kSC8",
        "title": "Research progress of the correlation between nuclear factor-κappa B and rheumatoid arthritis",
        "abstract": "Nuclear factor-κappa B(NF-κB) is an important transcription factor in the expression of any inflammatory media.The role of NF-κB in rheumatoid arthritis has been thought high recently.This review presents the role of NF-κB in rheumatoid arthritis,and the research progression of intervention therapy in inhibition of the activation of NF-κB is also introduced.",
        "keywords": [
            "Rheumatoid arthritis",
            "Nuclear factor-κappa B"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "Omv2RJLc": {
        "id": "Omv2RJLc",
        "title": "Is green tea drinking associated with a later onset of breast cancer?",
        "abstract": "BACKGROUND: Studies have found that tea polyphenols inhibit aromatase. Because of the substantial difference in levels of estrogens between premenopausal and postmenopausal women, the relationship between tea consumption and breast cancer risk may depend on menopausal status. METHODS: We examined this hypothesis in the Shanghai Women's Health Study, a population-based cohort study of 74,942 Chinese women. RESULTS: We found a time-dependent interaction between green tea consumption and age of breast cancer onset (p for interaction, 0.03). In comparison with non-tea drinkers, women who started tea-drinking at 25 years of age or younger had a hazard ratio (HR) of 0.69 (95% confidence interval [CI]: 0.41-1.17) to develop premenopausal breast cancer. On the other hand, compared with non-tea drinkers, women who started tea drinking at 25 years of age or younger had an increased risk of postmenopausal breast cancer with an HR of 1.61 (95% Cl: 1.18-2.20). Additional analyses suggest regularly drinking green tea may delay the onset of breast cancer. CONCLUSIONS: Further studies are needed to confirm our findings. Ann Epidemiol 2010;20:74-81. (C) 2010 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Green Tea",
            "Later Onset",
            "Breast Cancer",
            "Aromatase"
        ],
        "authors": [
            {
                "name": "Qi Dai",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, People's Republic of China"
            },
            {
                "name": "Gong Yang",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Martha J Shrubsole",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Butian Ji",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD"
            },
            {
                "name": "Wanqing Wen",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            },
            {
                "name": "Adrian Franke",
                "org": "Cancer Research Center of Hawaii, Honolulu"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, People's Republic of China"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt School of Medicine, Nashville, TN"
            }
        ],
        "venue": "Annals of Epidemiology",
        "year": 2010
    },
    "OVeOu7c4": {
        "id": "OVeOu7c4",
        "title": "Influence of Total Flavonoids of Epimedium on Serum Adiponectin in Hyperlipidemia Rats",
        "abstract": "Objective:To investigate the influence of total flavonoids of epimedium on adiponectin and the mechanism of its improvement of vascular endothelium in aorta of hyperlipidemia rats.Methods: 35 SD male rats were randomly divided into the high-fat diet group and the control group.After fat diet for 12 weeks,the high-fat diet group was randomly divided into the model group,the low-dose total favonoids of epimedium and the high-dose total favonoids of epimedium group.Being fed with corresponding drugs for 4 weeks,the serum lipid and the aortic pathological were detected.The level of adiponectin was tested by the ELISA method.Results: Compared with the model group,the TG level and the TC concentration were decreased in the low-dose and the high-dose total flavonoids of epimedium group.This drug could not only decrease the aortic imtimal injury and endometruim fracture,but also improve the smooth muscle proliferation and adiponictin level.Furthermore,the increase degree in the high dose group was more significant than that in the low dose group.Conclusion: The mechanism of that total flavonoids of epimedium can reduce the level of blood lipid,but increase the level of adiponectin could be related to its improve imtimal function and prevention of resistant with atherosclerosis.",
        "keywords": [
            "Total flavonoids of epimedium",
            "Hyperlipidemia",
            "Adiponectin",
            "Vascular endothelium"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Nanjing,Jiangsu "
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Nanjing,Jiangsu "
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Nanjing,Jiangsu "
            }
        ],
        "venue": "Journal of Emergency in Traditional Chinese Medicine",
        "year": 2011
    },
    "Kn4MG8cZ": {
        "id": "Kn4MG8cZ",
        "title": "Marital status and mortality among middle age and elderly men and women in urban Shanghai.",
        "abstract": "Previous studies have suggested that marital status is associated with mortality, but few studies have been conducted in China where increasing aging population and divorce rates may have major impact on health and total mortality.We examined the association of marital status with mortality using data from the Shanghai Women's Health Study (1996-2009) and Shanghai Men's Health Study (2002-2009), two population-based cohort studies of 74,942 women aged 40-70 years and 61,500 men aged 40-74 years at the study enrollment. Deaths were identified by biennial home visits and record linkage with the vital statistics registry. Marital status was categorized as married, never married, divorced, widowed, and all unmarried categories combined. Cox regression models were used to derive hazard ratios (HR) and 95% confidence interval (CI).Unmarried and widowed women had an increased all-cause HR = 1.11, 95% CI: 1.03, 1.21 and HR = 1.10, 95% CI: 1.02, 1.20 respectively) and cancer (HR = 1.17, 95% CI: 1.04, 1.32 and HR = 1.18, 95% CI: 1.04, 1.34 respectively) mortality. Never married women had excess all-cause mortality (HR = 1.46, 95% CI: 1.03, 2.09). Divorce was associated with elevated cardiovascular disease (CVD) mortality in women (HR = 1.47, 95% CI: 1.01, 2.13) and elevated all-cause mortality (HR = 2.45, 95% CI: 1.55, 3.86) in men. Amongst men, not being married was associated with excess all-cause (HR = 1.45, 95% CI: 1.12, 1.88) and CVD (HR = 1.65, 95% CI: 1.07, 2.54) mortality.Marriage is associated with decreased all cause mortality and CVD mortality, in particular, among both Chinese men and women.",
        "keywords": [
            "cox regression",
            "medicine",
            "physics",
            "behavior",
            "record linkage",
            "biology",
            "death rates",
            "confidence interval",
            "cohort study",
            "chemistry",
            "china",
            "engineering",
            "hazard ratio"
        ],
        "authors": [
            {
                "name": "Puthiery Va",
                "org": "University of New England College of Osteopathic Medicine(University of New England College of Osteopathic Medicine),Biddeford,United States"
            },
            {
                "name": "Wan-Shui Yang",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Shan Gao",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            }
        ],
        "venue": "PloS one",
        "year": 2011
    },
    "JaagXi9a": {
        "id": "JaagXi9a",
        "title": "Analysis and Countermeasures for Related Problems in Present Processes for Landfill Leachate Treatment",
        "abstract": "Problems and solutions associated with the operation of the current mainstream processes(pretreatment + biological treatment + advanced treatment) for landfill leachate treatment in China were analyzed.With the continuous development and application of new processes and technologies,the problems that the mainstream processes can not solve itself,such as insufficient carbon source,low yield,refractory concentrate and high energy consumption can be solved.",
        "keywords": [
            "landfill leachate",
            "concentrate",
            "energy consumption",
            "carbon source"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            },
            {
                "name": "XIONG Xiang-yang",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            },
            {
                "name": "CHEN Gang",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            }
        ],
        "venue": "China Water & Wastewater",
        "year": 2012
    },
    "hzsFOPV5": {
        "id": "hzsFOPV5",
        "title": "Method for treating allergies using substituted pyrazoles",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "christopher r butler",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "cheryl a grice",
                "org": ""
            },
            {
                "name": "yin gu",
                "org": ""
            },
            {
                "name": "darin j gustin",
                "org": ""
            },
            {
                "name": "lars karlsson",
                "org": ""
            },
            {
                "name": "haripada khatuya",
                "org": ""
            },
            {
                "name": "steven p meduna",
                "org": ""
            },
            {
                "name": "barbara a pio",
                "org": ""
            },
            {
                "name": "clark a sehon",
                "org": ""
            },
            {
                "name": "siquan sun",
                "org": ""
            },
            {
                "name": "kevin l tays",
                "org": ""
            },
            {
                "name": "robin l thurmond",
                "org": ""
            },
            {
                "name": "jianmei wei",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2003
    },
    "pEf9kBYk": {
        "id": "pEf9kBYk",
        "title": "Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.",
        "abstract": "More than 40 genetic susceptibility loci have been reported for type 2 diabetes (T2D). Recently, the combined effect of genetic variants has been investigated by calculating a genetic risk score. We evaluated 36 genome-wide association study (GWAS) identified SNPs in 2,679 T2D cases and 3322 controls in middle-age Han Chinese. Fourteen SNPs were significantly associated with T2D in analysis adjusted for age, sex and BMI. We calculated two genetic risk scores (GRS) (GRS1 with all the 36 SNPs and GRS2 with the 14 SNPs significantly associated with T2D). The odds ratio for T2D with each GRS point (per risk allele) was 1.08 (95% CI: 1.06-1.09) for GRS1 and 1.15 (95% CI: 1.13-1.18) for GRS2. The OR for quintiles were 1.00, 1.26, 1.69, 1.95 and 2.18 (P<0.0001) for GRS1 and 1.00, 1.33, 1.60, 2.03 and 2.80 (P<0.001) for GRS2. Participants in the higher tertile of GRS1 and the higher BMI category had a higher risk of T2D compared to those on the lower tertiles of the GRS1 and of BMI (OR = 11.08; 95% CI: 7.39-16.62). We found similar results when we investigated joint effects between GRS1 and WHR terciles and exercise participation. We finally investigated the joint effect between tertiles of GRSs and a composite high risk score (no exercise participation and high BMI and WHR) on T2D risk. We found that compared to participants with low GRS1 and no high risk factors for T2D, those with high GRS1 and three high risk factors had a higher risk of T2D (OR = 13.06; 95% CI: 8.65-19.72) but the interaction factor was of marginal significance. The association was accentuated when we repeated analysis with the GRS2. In conclusion we found an association between GRS and lifestyle factors, alone and in combination, contributed to the risk of and T2D among middle age Chinese.",
        "keywords": [
            "genome wide association study",
            "risk factors",
            "engineering",
            "diabetes mellitus",
            "genetic loci",
            "body weight",
            "biology",
            "medicine",
            "china",
            "genome wide association studies",
            "risk",
            "chemistry",
            "genotyping",
            "human genetics",
            "physics",
            "genetic predisposition",
            "genotype",
            "anthropometry"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Ryan Delahanty",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Scott M Williams",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Frank Hu",
                "org": "Harvard Univ, Cambridge, MA 02138 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Nashville, TN 37212 USA"
            }
        ],
        "venue": "GENETIC EPIDEMIOLOGY",
        "year": 2012
    },
    "wLIOxypw": {
        "id": "wLIOxypw",
        "title": "Association of genetic markers in the BCL-2 family of apoptosis-related genes with endometrial cancer risk in a Chinese population.",
        "abstract": "In vitro studies have demonstrated the role of the BCL-2 family of genes in endometrial carcinogenesis. The role of genetic variants in BCL-2 genes and their interactions with non-genetic factors in the development of endometrial cancer has not been investigated in epidemiological studies.We examined the relationship between BCL-2 gene family variants and endometrial cancer risk among 1,028 patients and 1,922 age-matched community controls from Shanghai, China. We also investigated possible interactions between genetic variants and established risk factors (demographic, lifestyle and clinical). Individuals were genotyped for 86 tagging single nucleotide polymorphisms (SNPs) in the BCL2, BAX, BAD and BAK1 genes.Significant associations with endometrial cancer risk were found for 9 SNPs in the BCL2 gene (P trend<0.05 for all). For SNPs rs17759659 and rs7243091 (minor allele for both: G), the associations were independent. The odds ratio was 1.27 (95% CI: 1.04-1.53) for women with AG genotype for the SNP rs17759659 and 1.82 (95% CI: 1.21-2.73) for women with the GG genotype for the SNP rs7243091. No interaction between these two SNPs and established non-genetic risk factors of endometrial cancer was noticed.Genetic polymorphisms in the BCL2 gene may be associated with the risk of endometrial cancer in Chinese women.",
        "keywords": [
            "medicine",
            "case control studies",
            "engineering",
            "genetic markers",
            "genetic predisposition",
            "biology",
            "chemistry",
            "physics",
            "apoptosis",
            "alleles",
            "human genetics"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Jiajun Shi",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Sandra Deming",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Jiarong Cheng",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "pDsUH4Qk": {
        "id": "pDsUH4Qk",
        "title": "Implementation of a novel unified power flow controller into Newton-Raphson load flow",
        "abstract": "This paper presents a novel structure of the unified power flow controller (UPFC) and proposes a load flow method for power systems with this kind of UPFCs. The novel UPFC structure has been applied in the Nanjing UPFC project, where the shunt converter is connected to a 35 kV bus, while two series converters are installed on two 220 kV lines. In this paper, the equivalent model of the novel UPFC is analyzed. Then a load flow method is proposed based on the power injection model and Newton-Raphson algorithm. The method can deal with the UPFC of both the novel structure and the conventional structure. The feasibility of the method is validated by test cases of the modified 39-bus New England system. The results show that the iteration number is acceptable under various operation conditions.",
        "keywords": "",
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Department of Electrical Engineering Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Department of Electrical Engineering Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Weiyuan Wang",
                "org": "State Grid Jiangsu Electric Power Company Nanjing, China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Electric Power Company Economic Research Institute Nanjing, China"
            }
        ],
        "venue": "power and energy society general meeting",
        "year": 2017
    },
    "lMqYgYum": {
        "id": "lMqYgYum",
        "title": "Factor analysis of quality guidelines for medical treatment",
        "abstract": "Objective: To explore the potential influencing factors of the quality guidelines for medical treatment by factor analysis.Method: We analyzed with the SPSS package 9 quality guidelines for medical treatment in the department of integrated TCM and Western medicine of a hospital,including the out-patient person-time,the number of discharges,the average days of hospitalization,the rate of bed utilization,the frequency of bed rotation,the rate of cure and improvement,the case fatality rate,the coincidence rate of diagnoses at admission and discharge,and the success rate of emergency treatment.Results: Four common factors were extracted,namely,the quantifiable factor,determined by the out-patient person-time,the number of discharges,the average days of hospitalization and the frequency of bed rotation;the treatment factor,determined by the cure and improvement rate and case fatality rate;the diagnostic factor,determined mainly by the rate of bed utilization and the coincidence rate of diagnoses at admission and discharge;and the emergency treatment factor,determined by the success rate of emergency treatment.The cumulative contribution rate of the 4 factors was 85.1%.Conclusion: The amount of medical work,the techniques of treatment,the ability of diagnosis and the efficiency of emergency rescue are the main influencing factors of quality guidelines for medical treatment.",
        "keywords": [
            "Management",
            "Hospitalization",
            "Factor analysis",
            "Out-patient service",
            "Medical treatment"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "YANG Cai-xia",
                "org": "Department of Informatics"
            },
            {
                "name": "FU Wan-ming",
                "org": "Department of Informatics"
            },
            {
                "name": "LIU Yu-xiu",
                "org": "Department of Medical Affairs,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "ggHnDgic": {
        "id": "ggHnDgic",
        "title": "Abstract 1900: Age at last birth and endometrial cancer risk: Pooled analysis in the Epidemiology of Endometrial Cancer Consortium",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jolanta lissowska",
                "org": ""
            },
            {
                "name": "pamela l hornross",
                "org": ""
            },
            {
                "name": "nicolas wentzensen",
                "org": ""
            },
            {
                "name": "noel s weiss",
                "org": ""
            },
            {
                "name": "penny webb",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "giske ursin",
                "org": ""
            },
            {
                "name": "marc t goodman",
                "org": ""
            },
            {
                "name": "sandra l deming",
                "org": ""
            },
            {
                "name": "kristin e anderson",
                "org": ""
            },
            {
                "name": "jennifer a doherty",
                "org": ""
            },
            {
                "name": "stalo karageorgi",
                "org": ""
            },
            {
                "name": "wendy cozen",
                "org": ""
            },
            {
                "name": "kristen b moysich",
                "org": ""
            },
            {
                "name": "malcolm c pike",
                "org": ""
            },
            {
                "name": "timothy r rebbeck",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "chu chen",
                "org": ""
            },
            {
                "name": "james r cerhan",
                "org": ""
            },
            {
                "name": "immaculata de vivo",
                "org": ""
            },
            {
                "name": "kim robien",
                "org": ""
            },
            {
                "name": "amanda b spurdle",
                "org": ""
            },
            {
                "name": "brian l strom",
                "org": ""
            },
            {
                "name": "jo l freudenheim",
                "org": ""
            },
            {
                "name": "rayna k matsuno",
                "org": ""
            },
            {
                "name": "susan e mccann",
                "org": ""
            },
            {
                "name": "hannah p yang",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "louise a brinton",
                "org": ""
            },
            {
                "name": "leslie bernstein",
                "org": ""
            },
            {
                "name": "veronica wendy setiawan",
                "org": ""
            },
            {
                "name": "thomas m mack",
                "org": ""
            },
            {
                "name": "galina lurie",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "QKgoFiOy": {
        "id": "QKgoFiOy",
        "title": "Radiofrequency catheter ablation for the refractory atrioventricular nodal reentrant tachycardia",
        "abstract": "Objective: To analyze the elcctrophysiological and clinical features of 68 common and 9 refractory atrioventricular nodal reentrant tachycardia(AVNRT) cases,thereby to seek safe and effective strategies for the treatment of refractory AVNRT with radiofrequency catheter ablation(RFCA). Methods: Ablation at lower zone is customarily applied in AVNRT,if noneffective,ablation electrode can be gradually moved upward,and radiofrequency energy can be delivered at a midpoint or upper position of His Bundle even with small H waves.The movement of the ablation electrode must be carefully monitored lest His bundle be eroded mistakenly.For those both atrioventricular nodal dual pathways(AVNDP) and atrioventricular accessory pathways(AVAP) are present,we always ablate AVAP first. Results: All 68 common AVNRT cases are simple slow-fast type.Among the 9 cases of refractory AVNRT,2 cases were combined with concealed left postseptal AVAP and concealed right AVAP respectively,while 1 case with atrioventricular nodal three pathways. Conclusion: X-ray anatomical position and intraventricular local mapping should be analyzed for the use of RFCA in refractory AVNRT.Safe and effective mapping should be: small A wave and big V wave,shattered A wave with width≥68 ms,A/V= 0.1-0.25,no H or H≤(0.02±0.03) mV.If lower position and middle position method are noneffective,linear ablation at mid-level of Koch's triangle seems to be a satisfactory alternative,which could avoid complications of atrioventricular block in the upper position ablation.",
        "keywords": [
            "Refractory atrioventricular nodal reentrant tachycardia",
            "Radiofrequency catheter ablation"
        ],
        "authors": [
            {
                "name": "LI Ping",
                "org": "Department of Cardiology"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,School of Medicine,Southern Medical University,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Qi-gao",
                "org": "Department of Cardiology"
            },
            {
                "name": "CHEN Rui-hua",
                "org": "Department of Cardiology"
            },
            {
                "name": "JIANG Shi-sen",
                "org": "Department of Cardiology"
            },
            {
                "name": "LIU Bao-jun",
                "org": ""
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "ynmssZ2s": {
        "id": "ynmssZ2s",
        "title": "A prospective study of dietary polyunsaturated fatty acids intake and lung cancer risk: Polyunsaturated fatty acids intake and lung cancer risk",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hung N. Luu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Hung N. Luu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Harvey J. Murff",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai JiaotongUniversity School of MedicineShanghai China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai JiaotongUniversity School of MedicineShanghai China"
            },
            {
                "name": "Jing Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai JiaotongUniversity School of MedicineShanghai China"
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Qing Lan",
                "org": "Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology & GeneticsNational Cancer Institute (NCI)Bethesda Maryland"
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt‐Ingram Cancer CenterVanderbilt University School of MedicineNashville Tennessee"
            }
        ],
        "venue": "International Journal of Cancer",
        "year": 2018
    },
    "1i9taEt6": {
        "id": "1i9taEt6",
        "title": "Vitamin supplement use during breast cancer treatment and survival: a prospective cohort study.",
        "abstract": "Background: Antioxidants may protect normal cells from the oxidative damage that occurs during radiotherapy and certain chemotherapy regimens; however, the same mechanism could protect tumor cells and potentially reduce effectiveness of cancer treatments. We evaluated the association of vitamin supplement use in the first 6 months after breast cancer diagnosis and during cancer treatment with total mortality and recurrence. Methods: We conducted a population-based prospective cohort study of 4,877 women aged 20 to 75 years diagnosed with invasive breast cancer in Shanghai, China, between March 2002 and April 2006. Women were interviewed approximately 6 months after diagnosis and followed up by in-person interviews and record linkage with the vital statistics registry. Results: During a mean follow-up of 4.1 years, 444 deaths and 532 recurrences occurred. Vitamin use shortly after breast cancer diagnosis was associated with reduced mortality and recurrence risk, adjusted for multiple lifestyle factors, sociodemographics, and known clinical prognostic factors. Women who used antioxidants (vitamin E, vitamin C, multivitamins) had 18% reduced mortality risk (HR = 0.82, 95% CI: 0.65-1.02) and 22% reduced recurrence risk (HR = 0.78, 95% CI: 0.63-0.95). The inverse association was found regardless of whether vitamin use was concurrent or nonconcurrent with chemotherapy, but was present only among patients who did not receive radiotherapy. Conclusions: Vitamin supplement use in the first 6 months after breast cancer diagnosis may be associated with reduced risk of mortality and recurrence. Impact: Our results do not support the current recommendation that breast cancer patients should avoid use of vitamin supplements. Cancer Epidemiol Biomarkers Prev; 20(2); 262-71. (C)2010 AACR.",
        "keywords": [
            "risk factors",
            "prospective studies",
            "vitamin d",
            "cohort studies",
            "young adult"
        ],
        "authors": [
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            },
            {
                "name": "Zhi Chen",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, IMPH,Div Epidemiol,Dept Med,Sch Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2011
    },
    "FyQGZygc": {
        "id": "FyQGZygc",
        "title": "Influence of Pioglitazone on Serum NO and MPO in Hyperlipidemia Rat",
        "abstract": "Objective:To investigate the effects of pioglitazone on hyperlipidemia,imflammation and oxidative stress induced functional impairment of the endothelium.Method:26 male SD rats were randomly devided into the high-fat diet group(n=17) and full diet group(control group,n=9).High-fat diet group was fed high-fat diet for 12 weeks,then serum lipid level was measured in the all rats,and which indicated that the hyperlipidemia model was estimated,and then high-fat diet group rats were randomly devided into two groups:hyperlipidemia group,high hyperlipidemia with pioglitazone group.By intragastric administration.Pioglitazone group rats were given pioglitazone(0.6mg/ml)for four weeks.Control group and model group rats were given tales doses of distilled water for four weeks.Then serum lipid level was measured in the rats.The aorta was taken for pathologic analysis.Serum level of NO,MPO was detected and compared with control(group).Results:After 12 weeks of feeding,as compared with control group the level of TG,TC,LDL in high-fat diet group was significantly increased (P<0.01),which indicated that the hyperlipidemia model was estimated.After 4 weeks' treatment,as compared with model group,the serum level of TG,TC and MPO decreased significantly (P<0.01),and the serum level of NO increased significantly (P<0.01) in pioglitazone group.Conclusion:NO defeciency and the increase of MPO are involved in vascular endothelium impairment,and pioglitazone can effective prevent vascular endothelium from impairment by restoring NO concentration and down-regulating MPO concentration in these rats.",
        "keywords": [
            "Rat",
            "Vascular endothelium impairment",
            "Pioglitazone",
            "Hyperlipidemia",
            "Nitric oxide",
            "Myeloperoxidase"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et al/Nanjing General Hospital of Nanjing Military Command,Nanjing "
            },
            {
                "name": "Xu Yushun",
                "org": ",et al/Nanjing General Hospital of Nanjing Military Command,Nanjing "
            },
            {
                "name": "Cai Jiayu",
                "org": ",et al/Nanjing General Hospital of Nanjing Military Command,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2010
    },
    "wMwUT1Tp": {
        "id": "wMwUT1Tp",
        "title": "An improved morphology connective criterion based on complete lattice for lane detection",
        "abstract": "",
        "keywords": [
            "image segmentation",
            "mathematical morphology",
            "complete lattice"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Jinhui Cai",
                "org": ""
            },
            {
                "name": "Guangxin Zhang",
                "org": ""
            },
            {
                "name": "Zekui Zhou",
                "org": ""
            }
        ],
        "venue": "Journal of Algorithms & Computational Technology",
        "year": 2008
    },
    "ZWPukcjb": {
        "id": "ZWPukcjb",
        "title": "Pre-diagnosis Body Mass Index and Waist-Hip Circumference Ratio in Association with Colorectal Cancer Survival.",
        "abstract": "The association of obesity on survival among patients with colorectal cancer (CRC) has not been well characterized. We investigated the association of pre-diagnostic body mass index (BMI)/waist-hip ratio (WHR) and total/cause-specific mortality in CRC patients. This study included 1,452 patients who participated in two large cohort studies and were diagnosed with CRC during follow-up period. Participants were measured for anthropometrics and interviewed to collect relevant information at baseline, prior to any cancer diagnosis. Data on site-specific cancer incidence and cause-specific mortality were obtained via in-person surveys and annual record linkage with cancer and vital statistics registries. Cox proportional hazard models were used to evaluate the associations of BMI and WHR with survival. A total of 547 participants died during the follow-up period, including 499 who died of CRC. Relative to normal BMI (18.5 to < 25.0 kg/m(2) ), obesity (BMI ≥ 30 kg/m(2) ) was associated with increased mortality resulting from all causes (Hazard Ratio (HR) = 1.5, 95% Confidence Interval (CI): 1.1-2.1) and CRC (HR = 1.5, 95% CI: 1.1-2.1). Elevated risk of death was also found among underweight patients (BMI <18.5 kg/m(2) ), although not all risk estimates were statistically significant. Overweight BMI (25.0 to < 30.0 kg/m(2) ) was not associated with risk of death among CRC patients, nor was WHR. In conclusion, pre-diagnostic BMI was associated with survival among CRC patients following a U-shape pattern; obesity was associated with high mortality after CRC diagnosis. These findings provide support for maintaining healthy weight to improve the survival of CRC patients. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "body mass index",
            "colorectal cancer",
            "obesity",
            "survival",
            "waist-hip ratio"
        ],
        "authors": [
            {
                "name": "Nan Wang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Nikhil K Khankari",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Hong-Lan Li",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA. wei.zheng@vanderbilt.edu."
            }
        ],
        "venue": "International journal of cancer",
        "year": 2016
    },
    "92BRz7z9": {
        "id": "92BRz7z9",
        "title": "Abstract 102: Circulating C-reactive protein and colorectal cancer risk: a report from the Shanghai Men's Health Study.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "jing gao",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "jie wu",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2013
    },
    "dIECsKJR": {
        "id": "dIECsKJR",
        "title": "P-225: Predictors of Phthalate and Phenol Exposure in Shanghai, China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "lawrence s engel",
                "org": ""
            },
            {
                "name": "wongho chow",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "nathaniel rothman",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "butian ji",
                "org": ""
            },
            {
                "name": "qiuying cai",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "antonia m calafat",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "jessie p buckley",
                "org": ""
            }
        ],
        "venue": "Epidemiology",
        "year": 2012
    },
    "09A4WedV": {
        "id": "09A4WedV",
        "title": "Clinical Research Progress on Safety of Antirheumatic Drugs with Slow Acting",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "SHEN Si-yu",
                "org": ""
            },
            {
                "name": "ZHANG Jun-hui",
                "org": ""
            },
            {
                "name": "ZHANG Yong-wen",
                "org": ""
            },
            {
                "name": "DONG Xiao-lei",
                "org": ""
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ""
            },
            {
                "name": "CAI Hui",
                "org": ""
            }
        ],
        "venue": "Occupation and Health",
        "year": 2008
    },
    "UijI6fS5": {
        "id": "UijI6fS5",
        "title": "Genetic Polymorphisms in the TGF-β1 Gene and Breast Cancer Survival: A Report from the Shanghai Breast Cancer Study",
        "abstract": "The effect of genetic polymorphisms in the TGF-β1 gene at codon 10 (T+29C), codon 25 (G+74C), and the promoter region [C → T at -509 from the transcription site, (C-509T)] on breast cancer survival was evaluated among a cohort of 1111 patients. The median follow-up time for the cohort was 5.17 years after cancer diagnosis. No DNA sequence variation at codon 25 of the TGF-β1 gene was found, whereas polymorphisms in C-509T and T+29C were in strong linkage disequilibrium. Patients who carried the C allele of T+29C polymorphism had a reduced 5-year disease-free survival rate (75.6% for T/C, and 78.2% for C/C) compared with the T/T genotype (85.1%; P, 0.04); the age-adjusted hazard ratio was 1.5 (95% confidence Interval, 1.1-2.2). Adjustment for clinical prognostic factors slightly attenuated the association (hazard ratio, 1.4, 95% confidence interval, 1.0-1.9). Our study suggests that genetic polymorphisms in the TGF-β1 gene may play a role in breast cancer progression.",
        "keywords": [
            "adjusted hazard ratio",
            "breast cancer",
            "linkage disequilibrium",
            "confidence interval",
            "polymorphism",
            "hazard ratio",
            "dna sequence"
        ],
        "authors": [
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "larry pierce",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "Zhi-Xian Ruan",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "fan jin",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2004
    },
    "VBSkA4ue": {
        "id": "VBSkA4ue",
        "title": "Tumor tissue microRNA expression in association with triple-negative breast cancer outcomes.",
        "abstract": "We evaluated suggested metastasis-related microRNAs (miRNAs) for their associations with disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer (TNBC). In a cohort of 456 TNBC cases, we systematically evaluated 57 previously reported metastasis-related miRNAs in tumor tissue using the NanoString nCounter assay. Cox regression was applied to evaluate miRNA expression in association with DFS and OS. In vitro assays using the TNBC cell line MDA-MB-231 were also conducted to validate epidemiological study findings. During a median follow-up of 5.3 years, 112 deaths and 97 recurrences were documented. High levels of miR-374b-5p, miR-218-5p, or miR-126-3p, or low levels of miR-27b-3p were independently associated with a favorable TNBC outcome (P < 0.01 for all). A composite score based on the levels of these four miRNAs was associated with DFS, with hazard ratios (95 % confidence interval) of 0.70 (0.43–1.15), 0.51 (0.29–0.90), and 0.18 (0.09–0.37) for the second, third, and fourth compared to the lowest quartile. Incorporating the miRNA score with known TNBC outcome predictors, i.e., age at diagnosis, tumor stage, and basal-like subtype, increased the C-index for predicting DFS from 0.68 to 0.74. Additionally, miR-126-3p was correlated with basal-like breast cancer, and miR-374b-5p modified the therapeutic effects of 5-Fluorouracil and Cyclophosphamide treatments in basal-like breast cancer patients. Restoring miR-126-3p, miR-218-5p, or miR-374b-5p, or inhibiting miR-27b-3p in MDA-MB-231 cells reduced cell proliferation. miR-374b-5p suppressed cell invasion and miR-218-5p inhibited colonization. This study provides strong evidence that the expression levels of miR-374b-5p, miR-27b-3p, miR-126-3p, and miR-218-5p in tumor tissues predict TNBC outcomes.",
        "keywords": [
            "miRNA",
            " TNBC",
            " Breast cancer",
            " Disease-free survival",
            " Overall survival"
        ],
        "authors": [
            {
                "name": "yongsuo liu",
                "org": "vanderbilt university"
            },
            {
                "name": "q cai",
                "org": "vanderbilt university"
            },
            {
                "name": "p p bao",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "yuanhui su",
                "org": "vanderbilt university"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "jianghong wu",
                "org": "vanderbilt university"
            },
            {
                "name": "fei ye",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "xiaofeng guo",
                "org": "vanderbilt university"
            },
            {
                "name": "weihong zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "x o shu",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Breast Cancer Research and Treatment",
        "year": 2015
    },
    "j4EujB6P": {
        "id": "j4EujB6P",
        "title": "Associations of adult height and its components with mortality: a report from cohort studies of 135,000 Chinese women and men.",
        "abstract": "Although several studies have evaluated the relationship between adult height and mortality, their results have not been entirely consistent. Little is known about components of adult height in relation to mortality, particularly in developing countries.We examined the association of adult height and its components (leg and trunk length) with mortality using data from 74 869 Chinese women and 61,333 men in the Shanghai Women's (1996-2008) and Men's (2002-2008) Health Studies. Anthropometric measurements, including standing and sitting height and weight, were taken at baseline by trained interviewers according to a standard protocol. Deaths were ascertained by biennial home visits and linkage with the vital statistics registry. Cox regression models were used to evaluate the associations.Neither height nor its components were associated with all-cause mortality. Height and, less consistently, its components were positively associated with cancer mortality, but inversely associated with cardiovascular disease (CVD) mortality. Hazard ratios (HRs) [95% confidence intervals (CIs)] for cancer mortality per 1-SD increment in height, trunk and leg length were 1.06 (1.01-1.12), 1.07 (1.01-1.12) and 1.03 (0.98-1.08), respectively, in women, and 1.13 (1.05-1.22), 1.09 (1.00-1.19) and 1.10 (1.03-1.16), respectively, in men. The corresponding HRs for CVD mortality were 0.89 (0.84-0.95), 0.93 (0.87-0.99) and 0.91 (0.86-0.98) in women, and 0.93 (0.86-1.02), 0.89 (0.81-0.98) and 0.99 (0.92-1.06) in men.Our results suggest that different mechanisms may be involved in linking height and its components with cancer and CVD mortality.",
        "keywords": [
            "cardiovascular disease",
            "cancer",
            "body height",
            "mortality",
            "cohort study",
            "chinese"
        ],
        "authors": [
            {
                "name": "Na Wang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Jing Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "International journal of epidemiology",
        "year": 2011
    },
    "itFlsoQW": {
        "id": "itFlsoQW",
        "title": "Accelerated aging in breast cancer survivors and its association with mortality and cancer recurrence.",
        "abstract": "To prospectively investigate accelerated aging and its association with total mortality and breast cancer-specific mortality/recurrence among breast cancer survivors. This study included 4218 female breast cancer patients enrolled into a population-based cohort study approximately 6-month post-diagnosis. Information on aging-related symptoms (i.e., self-rated overall health condition, energy level, depression, sleep difficulty, and quality) was collected at 18- and 36-month post-diagnosis surveys. Information on overall health, daily function impairments, survival status, and recurrence was collected at 10-year post-diagnosis survey. Record linkages with vital statistics were conducted to collect mortality information. Cox proportional hazards model was applied. Among 3041 10-year survivors with a mean age of 63.7 ± 9.7 years, respectively, 52.3%, 19.0%, and 27.6% reported poor health, limitation in daily activity, and climbing floors. Age-specific prevalence revealed that breast cancer survivors reached similar prevalence of the functional limitations 5–10 years earlier than cancer-free women. At the 18-month post-diagnosis survey, respectively, 47.0%, 72.5%, and 25.1% of survivors reported unsatisfied overall health condition, reduced energy level, and depression symptoms. After a median follow-up of 10.9 years, low self-rated overall health, low energy level, and depression were significantly associated with increased total mortality, with hazard ratios (HRs; 95% confidence intervals [CI]) of 3.14 (2.43, 4.06), 1.49 (1.20, 1.84), and 1.59 (1.21, 2.09), respectively. Low self-rated health was associated with breast cancer-specific mortality/recurrence (HR  1.85, 95% CI 1.30, 2.65). No significant association was found for sleep difficulty and quality. Aging-related physical changes/symptoms are commonly presented at 18 months after breast cancer diagnosis and are associated with worse prognosis. Our findings highlight the concern of accelerated aging among breast cancer survivors.",
        "keywords": [
            "Accelerated aging",
            " Energy",
            " Self-rated health",
            " Depression",
            " Sleep",
            " Breast cancer",
            " Mortality"
        ],
        "authors": [
            {
                "name": "Jingjing Zhu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, USA"
            },
            {
                "name": "Fei Wang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, USA"
            },
            {
                "name": "Liang Shi",
                "org": "Department of Chronic Non-Communicable Disease Surveillance, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, USA"
            },
            {
                "name": "Ying Zheng",
                "org": "Department of Cancer Control and Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, USA"
            },
            {
                "name": "Pingping Bao",
                "org": "Department of Chronic Non-Communicable Disease Surveillance, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, USA"
            }
        ],
        "venue": "Breast Cancer Research and Treatment",
        "year": 2020
    },
    "LpRrgDdM": {
        "id": "LpRrgDdM",
        "title": "Relation of blood pressure components and categories and all-cause, stroke and coronary heart disease mortality in urban Chinese women: a population-based prospective study.",
        "abstract": "Objective To determine whether various levels of blood pressure (BP), particularly normal and high normal BP or prehypertension, predict cardiovascular mortality among urban Chinese women. Methods We evaluated the impact of all measures of BP on total mortality and stroke and coronary heart disease (CHD)-specific mortality in a population-based cohort study, the Shanghai Women's Health Study. Included in this analysis were 68438 women aged 40-70 years at baseline for whom BP was assessed. Results During an average of 5 years of follow-up, we identified 1574 deaths from all causes, 247 from stroke and 91 from CHD. Hypertension and higher levels of individual BP parameters including systolic BP, diastolic BP, pulse pressure, and mean arterial pressure were positively associated with all-cause, stroke, and CHD mortality (P-trend<0.05 for all except for DBP and CHD mortality). Prehypertension [adjusted hazard ratio (HRadj)=1.65; 95% confidence interval, 0.98-2.78], particularly high normal BP (HRadj=2.34; 95% confidence interval, 1.32-4.12), was associated with an increased risk of mortality from stroke. Hypertension accounted for 9.3% of mortality from all causes, 25.5% of mortality from stroke, and 21.7% mortality from CHD. High normal BP accounted for 10.8% of mortality from stroke. Isolated systolic BP also predicted stroke and mortality from CHID. Conclusion Hypertension is a significant contributor to mortality, particularly stroke and CHID mortality, among women in Shanghai. High normal BP is associated with high stroke mortality. J Hypertens 27:468-475 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.",
        "keywords": [
            "blood pressure",
            "China",
            "cohort study",
            "mortality",
            "prehypertension",
            "stroke",
            "women"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Med Ctr,Dept Med,Sch Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Lifeng Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Nashville, TN 37203 USA"
            }
        ],
        "venue": "JOURNAL OF HYPERTENSION",
        "year": 2009
    },
    "uiahTXSg": {
        "id": "uiahTXSg",
        "title": "Regulations of acupuncture on hepatic tissue IRS2 gene expression in type 2 diabetes rats",
        "abstract": "Objective:To study the relationship between hepatic tissue insulin receptor substrate 2(IRS2) gene and type 2 diabetes,and the regulation of acupuncture on IRS2 gene expression of hepatic tissue in type 2 diabetes mellitus(T2DM) rats.Methods:Obese rats due to diet were injected in abdomen with small dose streptozotocin(STZ) to induce T2DM.Then these T2DM rats were stochastically divided into acupuncture group,Glibenclamide group and model group.After 4 weeks treatment,fasting blood sugar(FBS) was examined with active blood sugar meter,fasting insulin(FINS) was examined by radioimmunoassav,hepatic tissue IRS2mRNA was evaluated in real-time RT PCR,and normal rats were in control.Results:Serum levels of FBS(15.79±1.87) and FINS(37.20±3.92) in model group were higher than those in normal group(5.16±0.13,23.57±1.63),serum levels of FBS(5.46±0.20) and FINS(20.87±1.80) in acupuncture group were obviously lower than those in model group,which were similar to normal group.FBS(5.26±0.13) reduced obviously and serum FINS(28.10±1.86) reduced in some degree in Glibenclamide group compared with model.Relative contents of IRS2mRNA in model group were 2.19 folds compared with that in normal group.And in Glyburide group it was 4.59 folds compared with that in normal group.In acupuncture group it was 4.04% of that in the normal group.Conclusion:Abnormal hepatic tissue IRS2 mRNA expression may be one of pathogenesis of T2DM.Acupuncture can obviously depress hepatic tissue IRS2 mRNA expression,but Glibenclamide can not.",
        "keywords": [
            "IRS2 mRNA",
            "Acupuncture",
            "Real-time RT PCR",
            "Type 2 diabetes"
        ],
        "authors": [
            {
                "name": "YUAN Ai-hong",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "LIU Zhi-cheng",
                "org": "The second clinical medical college of Nanjing University of Chinese Medicine,Nanjing ,China"
            },
            {
                "name": "WEI Qun-li",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "China Journal of Traditional Chinese Medicine and Pharmacy",
        "year": 2010
    },
    "pizY7M1I": {
        "id": "pizY7M1I",
        "title": "Influence of Total Flavonoids of Epimedium on Serum NO and MPO in Rats with Hyperlipidemia",
        "abstract": "Objective To investigate the effects and mechanisms of total flavonoids of epimedium(TFE) on improvement of hyperlipidemia,inflammation and oxidative stress in functional impairment of the endothelium.Methods Thirty-five SD male rats were randomly divided into four groups:Control group(n=9) fed with normal diet for sixteen weeks,hyperlipidemia group(n=8) fed with high-cholesterol diet for sixteen weeks,TFE low dose group(n=9) and TFE high dose group(n=9) fed with high-cholesterol diet for sixteen weeks supplemented with TFE from the twelveth weeks of cholesterol diet.Serum levels of triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),nitric oxide(NO) and myeloperoxidase(MPO) were detected.Results Compared with control,the serum levels of TG,TC,MPO were increased significantly in hyperlipidemia group(P<0.01).Compared with hyperlipidemia group,the serum levels of TG,TC were decreased in TFE group.The contents of serum NO in hyperlipidemia group were higher than that in control group and TFE group(P<0.05 or P<0.01).Compared with hyperlipidemia group,the serum levels of MPO were decreased in TFE group(P<0.01).The levels of TFE high dose group were lower than that of TFE low dose group(P<0.05).Conclusion NO defeciency and the increase of MPO could be involved in vascular endothelium impairment with oxidative stress in rats with high-fat diet-induce hyperlipidmia,and TFE could ameliorate vascular endothelium impairment by up-regulating NO concentration and down-regulating MPO concentration in rats.",
        "keywords": [
            "nitric oxide",
            "vascular endothelium impairment",
            "total flavonoids of epimedium",
            "hyperlipidemia",
            "myeloperoxidase"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et alNanjing General Hospital of Nanjing Military Command%%#Nanjing %%#"
            },
            {
                "name": "Guo Junhao",
                "org": ",et alNanjing General Hospital of Nanjing Military Command%%#Nanjing %%#"
            },
            {
                "name": "Dong Xiaolei",
                "org": ",et alNanjing General Hospital of Nanjing Military Command%%#Nanjing %%#"
            }
        ],
        "venue": "Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease",
        "year": 2010
    },
    "ItPkSLpp": {
        "id": "ItPkSLpp",
        "title": "On-line inspection method for steel billet characters based on improved template matching",
        "abstract": "To avoid local distortion,stroke break and thickness variation in steel billets characters,a real-time online identification system based on improved template matching was proposed.Through image processing technique including grayscale area filter,improved auto-threshold algorithm,noises were filtered and characters were extracted from the image.Single character was achieved by using projection function.Classical template matching technique was improved by membership assignment conception to recognize characters robustly.Experimental results proved the feasibility and effectiveness of the system.Stability and real-time performance of the method were catering to production requirements.",
        "keywords": [
            "Automatic vision inspection",
            "Characters on steel billet",
            "Figure character recognition",
            "Template matching"
        ],
        "authors": [
            {
                "name": "ZHANG Hao",
                "org": "National Key Lab of Industrial Control Technology,Department of Control Science & Engineering,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "CAI Jin-hui",
                "org": "National Key Lab of Industrial Control Technology,Department of Control Science & Engineering,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "National Key Lab of Industrial Control Technology,Department of Control Science & Engineering,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Computer Integrated Manufacturing Systems",
        "year": 2007
    },
    "xTrEXsOH": {
        "id": "xTrEXsOH",
        "title": "Association of ginseng use with survival and quality of life among breast cancer patients.",
        "abstract": "The authors evaluated the associations of ginseng use as a complementary therapy with survival and quality of life (QOL) in a cohort of 1,455 breast cancer patients who were recruited to the Shanghai Breast Cancer Study between August 1996 and March 1998 in Shanghai, China. Patients were followed through December 2002. Information on ginseng use before cancer diagnosis was collected at baseline recruitment and was linked to survival. Survivors' ginseng use after cancer diagnosis was obtained at the follow-up survey and was correlated to QOL at the same time. The Kaplan-Meier method and Cox regression models were applied to evaluate the association of ginseng use with overall and disease-free survival. The relation of ginseng use and QOL was evaluated by using multiple linear regression models. Approximately 27% of study participants were regular ginseng users before cancer diagnosis. Compared with patients who never used ginseng, regular users had a significantly reduced risk of death; adjusted hazard ratios associated with ginseng use were 0.71 (95% confidence interval: 0.52, 0.98) for total mortality and 0.70 (95% confidence interval: 0.53, 0.93) for disease-specific mortality/recurrence. Ginseng use after cancer diagnosis, particularly current use, was positively associated with QOL scores, with the strongest effect in the psychological and social well-being domains. Additionally, QOL improved as cumulative ginseng use increased.",
        "keywords": [
            "breast neoplasms",
            "complementary medicine",
            "ginseng",
            "quality of life",
            "survival"
        ],
        "authors": [
            {
                "name": "Yong Cui",
                "org": "Department of Medicine|Center for Health Services Research|Vanderbilt-Ingram Cancer Center|Vanderbilt University"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Department of Medicine|Center for Health Services Research|Vanderbilt-Ingram Cancer Center|Vanderbilt University"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology|Shanghai Cancer Institute"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine|Center for Health Services Research|Vanderbilt-Ingram Cancer Center|Vanderbilt University"
            },
            {
                "name": "Meng-Hua Tao",
                "org": "Department of Medicine|Center for Health Services Research|Vanderbilt-Ingram Cancer Center|Vanderbilt University"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine|Center for Health Services Research|Vanderbilt-Ingram Cancer Center|Vanderbilt University"
            }
        ],
        "venue": "AMERICAN JOURNAL OF EPIDEMIOLOGY",
        "year": 2006
    },
    "AfpAAnfM": {
        "id": "AfpAAnfM",
        "title": "Establishment of model of isoprenaline-induced chronic heart failure in rats",
        "abstract": "Objective:To establish the model of isoprenaline(ISO)-induced chronic heart failure(CHF) in rats and to assess the value.Methods:The ISO-induced group(ISO group,n=50) received two subcutaneous injections of 170 mg ISO per kilogram of body and the healthy control group(NS group,n=10) received two subcutaneous injections of 0.25 ml normal saline.The left ventricular end-diastolic dimension(LVEDD),left ventricualr end-systolic dimension(LVESD),left ventricular ejection fraction(LVEF) and shortening fractionl(FS) were detected by echocardiogram at 3,6 and 18 weeks after the injection.Eighteen weeks later,the mass ratio of heart ventricle and left ventricle were measured.Results:As time went on,the degree of CHF became more serious and there was an increase of mortality(P<0.01).Along with the decrease of LVEF and FS,LVEDD and LVESD increased significantly(P<0.01);the mass ratio of heart ventricle and left ventricle increased significantly(P<0.01).Conclusions:High-dose of ISO-induction is a simple,convenient and reliable method to trigger the rat model of CHF.Echocardiographic assessment is instructive in this species.",
        "keywords": [
            "models",
            "congestive",
            "heart failure",
            "rats",
            "echocardiography",
            "isoprenaline",
            "animal"
        ],
        "authors": [
            {
                "name": "CHEN Xiang-min",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing Jiangsu ,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing Jiangsu ,China"
            },
            {
                "name": "SONG Yao-hong",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing Jiangsu ,China"
            }
        ],
        "venue": "Journal of Bengbu Medical College",
        "year": 2008
    },
    "US75JIHJ": {
        "id": "US75JIHJ",
        "title": "Differentiation of monkey bone marrow mesenchymal stem cells into adipocytes in vitro",
        "abstract": "Purpose To induce bone marrow mesenchymal stem cells of rhesus monkey to differentiate into adipocytes in vitro.Methods Bone marrow was harvested from 2 ～ 3 years old male rhesus monkey ilium,and mesenchymal stem cells were isolated by density low centrifugation and plastic adhesion.And their multidirectional differentiation ability was evaluated.In the experimental group BMSCs of P3 / P5 / P8 were cultivated with adipocytic differentiation medium,and control group were cultivated with conventional medium.Oil red O staining was performed to confirm lipid form at three weeks and adipocytic differentiation rate was analyzed.Results The bone marrow mononuclear cells extracted from monkey had osteogenetic differentiation ability,which showed the characteristics known as pluripotency.The fifth day after differentiation cultivating,lipid drops were observed in a few cells in the cytoplasm of the experimental group.Then the adipocyte number,and the number and the size of lipid drops gradually increased to peak about three weeks.Adipocytic differentiation rate respectively was(48.3 ± 10.0) %(P3),(58.7 ± 5.3) %(P5),(68.1 ± 5.5) %(P8),and the difference had statistical significance(P < 0.05).Conclusion Rhesus monkey BMSCs could been induced by adipocytic differentiation medium to differentiate to adipocyte directionally in vitro.",
        "keywords": [
            "mesenchymal stem cell",
            "differentiation",
            "induction",
            "monkey",
            "adipocyte",
            "bone marrow"
        ],
        "authors": [
            {
                "name": "LIU Xiao-gang",
                "org": "Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            },
            {
                "name": "DENG Yu-bin",
                "org": "Department of Pathology and Pathophysiology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou ,China"
            },
            {
                "name": "ZHAO Xiao-juan",
                "org": "Department of Ophthalmology,Beijing Aerospace General Hospital,Beijing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            },
            {
                "name": "WANG Li-ning",
                "org": "Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            },
            {
                "name": "ZHANG Xin-peng",
                "org": "Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Clinical and Experimental Pathology",
        "year": 2013
    },
    "MPbiBurw": {
        "id": "MPbiBurw",
        "title": "Use of oral contraceptives, intrauterine devices and tubal sterilization and cancer risk in a large prospective study, from 1996 to 2006.",
        "abstract": "The association of contraceptive methods, including oral contraceptives (OC), intrauterine devices (IUD) and tubal sterilization (TS), with overall and site-specific cancer were prospectively investigated in a cohort of 66,661 Chinese women in Shanghai, 76.7% of whom used contraception. During a median follow-up time of 7.5 years, 2,250 women were diagnosed with cancer. Ever-use of any contraceptive method was not associated with overall cancer risk [adjusted hazard ratio (HR(adj)) = 1.02, 95% CI, 0.92-1.12]. Use of any contraceptive method was associated with increased risk of rectal cancer (HR(adj) = 1.68, 95% CI, 1.08-2.62) and reduced risk of thyroid cancer (HR(adj) = 0.63, 95% CI, 0.38-1.04). Risk of gallbladder cancer increased with ever use of OC (HR(adj) = 2.38, 95% CI, 1.26-4.49). IUD use was associated with a possible reduced risk of thyroid cancer (HR(adj) = 0.64, 95% CI, 0.38-1.07). Longer duration of IUD use decreased risk for breast, thyroid and lung cancers. Ever having a TS was associated with increased uterine body cancer (HR(adj) = 2.50, 95% CI, 1.47-4.25) and decreased risk of stomach cancer (HR(adj) = 0.59, 95% CI, 0.39-0.91). We did not find any contraceptive method to be related to the risk of ovarian cancer but the analyses were based on few events. Although chance findings are a likely explanation for some of the associations found in our study, these findings suggest that various contraceptive methods or reproductive patterns may play a role in the etiology of cancer.",
        "keywords": [
            "neoplasms",
            "intrauterine device",
            "china",
            "tubal sterilization",
            "oral contraceptives",
            "developed countries",
            "rectal cancer",
            "population",
            "prospective study",
            "prospective studies",
            "thyroid gland",
            "sterilization",
            "risk factors",
            "developing countries"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Hong-Lan Li",
                "org": ""
            },
            {
                "name": "Han-Zhu Qian",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "International journal of cancer. Journal international du cancer",
        "year": 2009
    },
    "YvTiPuxv": {
        "id": "YvTiPuxv",
        "title": "Effects of total flavonoids of epimedium on nitric oxide in myocardium of rats with congestive heart failure",
        "abstract": "Objective To explore the effects of total flavonoids of epimedium(TFE)on nitric oxide(NO)in the myocardium of rats with congestive heart failure(CHF).Methods One hundred male SD rats were randomly allocated to isoproterenol(ISO)-induced CHF groups(ISO,n=90)receiving two subcutaneous injections of 170mg/kg ISO and healthy normal group(NOR,n=10)receiving two subcutaneous injections of 0.25ml normal saline.On the 6th week,left ventricular ejection fraction(LVEF)was measured by echocardiogram and the rats with LVEF≤45% were considered as CHF.CHF rats were divided into 2 subgroups of compensation(COMP)and decompensation(DECOMP).The rats of DECOMP were randomly divided into 5 groups of control(CON,NS 0.1ml·kg-1·d-1),metoprolol(MET,metoprolol 8mg·kg-1·d-1),TFE low-dose(TFE-L),TFE medium-dose(TFE-M)and TFE high-dose(TFE-H).On the 18th week,the heart function parameters(LEVF,FS,LVEDD,LVESD)and LVWI were measured after LV morphopathological examination.NO was detected by enzyme immunoassay method.ResultsCompared with group NOR,heart function was significantly deteriorated with the increases in VWI,LVWI,pathological scores and NO in the myocardium(P<0.05)in groups of CON and COMP.Compared with groups of CON and COMP,the VWI,LVWI,pathological scores and NO in the myocardium were decreased distinctly(P<0.05)and heart function was improved remarkably in groups of TFE and MET.Conclusion TFE can improve heart function and down-regulate NO in the myocardium of rats with CHF.",
        "keywords": [
            "Total flavonoids of epimedium",
            "Nitric oxide",
            "Congestive heart failure"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al.Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,CHINA"
            },
            {
                "name": "CAI Jiayu",
                "org": ",et al.Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,CHINA"
            },
            {
                "name": "LU Le",
                "org": ",et al.Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2010
    },
    "lpMXD8mN": {
        "id": "lpMXD8mN",
        "title": "Dietary B vitamin and methionine intakes and breast cancer risk among Chinese women",
        "abstract": "Methionine, folate, vitamin B(6), vitamin B(12), niacin, and riboflavin intakes may be related to breast carcinogenesis. These associations may vary by breast cancer type. Using the prospective cohort Shanghai Women's Health Study (1997-2008) including 718 Chinese breast cancer cases, the authors evaluated baseline dietary intake of these factors and breast cancer risk and whether the associations varied by menopausal status and estrogen receptor (ER) and progesterone receptor (PR) status. They estimated associations using hazard ratios and 95% confidence intervals from Cox proportional hazards regression models and stratified analyses by menopausal status and ER/PR status. Lowest quantile of intake was used as the comparison group. For postmenopausal women, dietary intakes of methionine and B vitamins were not associated with breast cancer risk. For premenopausal women, higher intake of folate was associated with decreased breast cancer risk (hazard ratio = 0.58, 95% confidence interval: 0.34, 0.99 for the highest vs. lowest quintile of intake). Only niacin intake was associated with ER+/PR+ breast cancer risk (hazard ratio = 1.62, 95% confidence interval: 1.07, 2.46; P for trend = 0.04 for the highest vs. lowest quartile of intake). Findings support the hypothesis that high folate intake may reduce breast cancer risk and that the association may vary by menopausal and ER/PR status.",
        "keywords": [
            "breast neoplasms",
            "cohort studies",
            "diet",
            "estrogen receptor alpha",
            "folic acid",
            "niacin",
            "premenopause"
        ],
        "authors": [
            {
                "name": "Martha J. Shrubsole",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Yutang Gao -",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Jin Gao",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Epidemiol Ctr, Div Epidemiol, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF EPIDEMIOLOGY",
        "year": 2011
    },
    "Jk5wMRKP": {
        "id": "Jk5wMRKP",
        "title": "The long-term impact of medical and socio-demographic factors on the quality of life of breast cancer survivors among Chinese women.",
        "abstract": "Quality of life (QOL) has become an integral part of the modern assessment of cancer treatment in Western society. However, little is known about the QOL of Chinese breast cancer survivors. To evaluate the long-term impact of medical and socio-demographic factors on survivors' QOL, we conducted a population-based study of 1065 breast cancer survivors in Shanghai, China. The mean age at diagnosis was 48.1 years and the median survival time was 4.3 years for the study participants. The Generic Quality of Life Inventory was used to assess survivors' QOL. Multiple linear regression models were employed to analyze the associations of QOL outcomes with socio-demographic and medical factors. The results revealed that recurrence status, time since diagnosis, marital status, income and education all had an independent, significant association with overall QOL and differential domains of QOL. Age at diagnosis exhibited a dual effect on QOL, positively associated with material well-being and negatively associated with physical well-being. Stage of disease was only associated with social well-being, while the type of surgery was related to material well-being alone. No associations between QOL and chemotherapy or radiotherapy were found. Further, analyses by survival intervals suggested a domain-specific order of recovery of QOL after cancer treatment. These results fill gaps in the limited literature, and provide valuable information for physicians to target the specific needs of Chinese women with breast cancer, choose appropriate interventions at the optimal time, and develop strategies accordingly in terms of improvement of patient's QOL.",
        "keywords": [
            "breast cancer survivors",
            "Chinese women",
            "quality of life",
            "socio-demographic and medical factors"
        ],
        "authors": [
            {
                "name": "Yong Cui",
                "org": "Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center,Vanderbilt University,Nashville,USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Department of Medicine,Vanderbilt University, Center for Health Services Research, 6th floor, Medical Center East,Nashville,USA; Tel.:"
            },
            {
                "name": "Yutang Gao",
                "org": "Department of Epidemiology,Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center,Vanderbilt University,Nashville,USA"
            },
            {
                "name": "Wanqing Wen",
                "org": "Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center,Vanderbilt University,Nashville,USA"
            },
            {
                "name": "Zhi-Xian Ruan",
                "org": "Department of Epidemiology,Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "Fan Jin",
                "org": "Department of Epidemiology,Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine, Center for Health Services Research and Vanderbilt-Ingram Cancer Center,Vanderbilt University,Nashville,USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2004
    },
    "XsbPfXqY": {
        "id": "XsbPfXqY",
        "title": "For Peer Review Circulating C-reactive protein and colorectal cancer risk: a report from the Shanghai Men's Health Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie wu",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "anQHBxqw": {
        "id": "anQHBxqw",
        "title": "The Effect of Curcumin on the Immune Organ's Weight and Expression of TNF-α IL-1β in Blood Serum of Adjuvant Arthritis Rats",
        "abstract": "Objective:To explore the possible role of curcumin in rheumatoid arthritis(RA) by detecting the expression of TNF-α and IL-1β in synovial fluid and blood serum of adjuvant arthritis rats,offer theory and experiment evidence for curcumin′s clinically apply.Methods:The experimental SD rat model AA was set up by intradermal injection of freund′s complete adjuvant(FCA),rats were grouped randomly into three groups: normal,triptolide and curcumin group.after 15 days,through recipe articular genu's rinse solution and blood,The expressions of TNF-α and IL-1β in synovial fluid and blood serum were detected by ELISA.and recipe thymus,spleen,weighing by electronic balance.Results:compared with normal group,the expressions of TNF-α and IL-1β in blood serum were increased(P<0.05),after drug treatment there was statistical difference in above indexes between normal group and curcumin group(P<0.05),the affected rats treated with curcumin can cut down thymic weight,display statistical significance.Conclusion:Curcumin may play a protective role in RA by downregulating the expression of TNF-α and IL-1β,and cut down thymic weigh,so it has depressant effect of anti-inflammatory and immunological inhibition.",
        "keywords": [
            "TNF-α",
            "weight of immune organ",
            "adjuvant arthritis",
            "IL-1β",
            "curcumin"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHENG Zhao-ling",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2009
    },
    "gKw1UmzH": {
        "id": "gKw1UmzH",
        "title": "Exercise after diagnosis and metabolic syndrome among breast cancer survivors: a report from the Shanghai Breast Cancer Survival Study.",
        "abstract": "Metabolic syndrome (MetS) is an established risk factor for cardiovascular diseases and mortality. Limited data are available on the prevalence of MetS and its association with exercise among breast cancer survivors. The present study included 1,696 breast cancer survivors from the Shanghai Breast Cancer Survival Study, a population-based prospective cohort study conducted between April 2002 and October 2011 in Shanghai, China. All women had a physical examination taken at study clinic approximately 60 months post-diagnosis. Exercise was assessed at approximately 6, 18, 36, and 60 months post-diagnosis. Information on medical history, tumor characteristics, cancer treatment, anthropometrics, and lifestyle was collected at study enrollment. Associations between exercise and MetS at 60 months post-diagnosis were evaluated with multivariable logistic regression models. The mean age of the study population was 56.68 at 60-month survey, and the mean follow-up since cancer diagnosis was 63.66 months. The prevalence of MetS using National Cholesterol Education Program Adult Treatment Panel III criteria at approximately 60 months after diagnosis was 33.14%. Among overweight and obesity breast cancer survivors (body mass index (BMI) ≥ 25 kg/m(2) at baseline), the prevalence was 55.18%. The most common type of exercise in this population was walking (45.40%) at baseline. Exercise participation between 6 and 60 months post-diagnosis was inversely associated with the prevalence of MetS with the adjusted odds ratio (OR) for exercise participation of ≥ 3.5 h/week (30 min/day) being 0.69 (95% confidence interval (CI) 0.48-0.98). In addition consistent exercise participation reduced the prevalence of MetS (adjusted OR 0.70 (95% CI 0.50-1.00). Associations of exercise with MetS were not modified by baseline waist circumference, BMI, comorbidity, baseline menopausal status, TNM stage, cancer treatment, or ER/PR status (p interactions > 0.05). Regular and persistent exercise after cancer diagnosis, even at low-to-moderate intensity level, decreases the prevalence of MetS among long-term breast cancer survivors.",
        "keywords": [
            "breast cancer",
            "exercise",
            "metabolic syndrome",
            "survivorship",
            "china",
            "risk factors",
            "obesity",
            "survival analysis",
            "cohort studies",
            "questionnaires"
        ],
        "authors": [
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Peng Peng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            }
        ],
        "venue": "Cancer causes & control : CCC",
        "year": 2013
    },
    "eRrJfydr": {
        "id": "eRrJfydr",
        "title": "Meta-analysis of total glucosides of paeony combined with methotrexate in treatment for rheumatoid arthritis",
        "abstract": "Objective It is to evaluate the effect and safety of total glucosides of paeony combined with methotrexate(MTX) in patients with rheumatoid arthritis(RA).Methods All clinical random controlled studies were identified by searching CNKI(1994-2008) and Medline(1989-2008/11).The quality of included studies was assessed according to the criteria recommended Cochrane Collaboration.Meta-analyses were performed using Rev2Man5.0 software.Results 7 trials were included,2 studies of them were grade A and the others were grade B.Meta-analyses showed that four trials evaluated the total effective rate after treated for 12 weeks according the ACR criterion,OR 3.41(95%CI: 0.77,15.10),Z=1.62,P=0.11,and 2 trials did after 24 weeks,OR 0.95(95%CI: 0.14,6.55),Z=0.06,P=0.96.5 trial reported the incidence rate of leukopenia after treated,OR 0.49(95%CI: 0.21,1.11),Z=1.71,P=0.09.6 trials reported the incidence rate of impaired liver function after treated,OR 0.41(95%CI: 0.20,0.82),Z=2.53,P=0.01.Conclusion The total effective rate of total glucosides of paeony combined with MTX is much better than that of MTX in treating the patients with RA.At the same time,it can reduce adverse effects,such as reduce the incidence rate of impaired liver function significantly.",
        "keywords": [
            "meta-analysis",
            "rheumatoid arthritis",
            "total glucosides of paeony"
        ],
        "authors": [
            {
                "name": "Shang Wei",
                "org": "Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Guo Junhao",
                "org": "Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command of PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2010
    },
    "ylog059i": {
        "id": "ylog059i",
        "title": "E-cadherin promoter polymorphisms are not associated with the aggressiveness of prostate cancer in Caucasian patients.",
        "abstract": "-160C-->A and -347G-->GA polymorphisms in the promoter region decrease E-cadherin gene transcription. Decreased E-cadherin expression predicts poor outcome among patients with cancer. We sought to investigate whether -160C-->A and/or -347G-->GA polymorphisms were associated with the aggressiveness of prostate cancer.TaqMan single nucleotide polymorphism genotyping assay (Applied Biosystems, Foster City, CA) was used to detect -160C-->A and -347G-->GA polymorphisms in deoxyribonucleic acid from the paraffin-embedded prostate tissues of 98 Caucasian patients.The genotype frequencies were -160C/C: 48% (47 of 98); -160C/A: 44% (43 of 98); -160A/A: 8% (8 of 98); -347G/G: 68% (67 of 98); -347G/GA: 28% (27 of 98); and -347GA/GA: 4% (4 of 98). Using the chi-square test, we found that the polymorphisms -160C-->A and -347G-->GA were not related to other clinical and pathologic parameters (i.e., age, prostate-specific antigen level, Gleason grade, and clinical stage) (P > 0.05). In combination analysis, there was no significant relationship between patients with both -160C/C and -347G/G, and these same parameters (P > 0.05). Using the log-rank test, we found no significant difference in relapse-free survival and overall survival between patients with -160C/C and those with -160A/C or -160A/A (P = 0.0764 and 0.2746, respectively), and also no significant difference between patients with -347G/G and those with -347GA/G or -347GA/GA (P = 0.9416 and 0.7367, respectively). There was also no significant difference in relapse-free survival and overall survival between patients with homozygosities of -160C/-347G and patients with other genotypes (P = 0.1418 and 0.2434, respectively).We conclude that E-cadherin -160C-->A and/or -347G-->GA polymorphisms are not associated with the aggressiveness of prostate cancer in Caucasian patients.",
        "keywords": [
            "prostate cancer",
            "aggressiveness",
            "e-cadherin",
            "polymorphism",
            "promoter",
            "gene transcription",
            "e cadherin"
        ],
        "authors": [
            {
                "name": "He-Cheng Li",
                "org": "Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Jeffrey M Albert",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Eric T Shinohara",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Andrea Freyer",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Carolyn Cao",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Zuofei Wang",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Nobuhiko Kataoka",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Ming Teng",
                "org": "Department of Radiation Oncology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA"
            },
            {
                "name": "Bo Lu",
                "org": ""
            }
        ],
        "venue": "Urologic oncology",
        "year": 2006
    },
    "FLMKPRMN": {
        "id": "FLMKPRMN",
        "title": "Band Engineering by Controlling vdW Epitaxy Growth Mode in 2D Gallium Chalcogenides.",
        "abstract": "Atomically thin quasi-2D GaSe flakes are synthesized via van der Waals (vdW) epitaxy on a polar Si (111) surface. The bandgap is continuously tuned from its commonly accepted value at 620 down to the 700 nm range, only attained previously by alloying Te into GaSe (GaSexTe1-x). This is accomplished by manipulating various vdW epitaxy kinetic factors, which allows the choice bet ween screw-dislocation-driven and layer-bylayer growth, and the design of different morphologies with different material-substrate interaction (strain) energies.",
        "keywords": [
            "2D materials",
            "band engineering",
            "van der Waals epitaxy"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Emmanuel Soignard",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Can Ataca",
                "org": "MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Changhyun Ko",
                "org": "Univ Calif Berkeley, Dept Mat Sci & Engn, Berkeley, CA 94720 USA"
            },
            {
                "name": "Toshihiro Aoki",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Anupum Pant",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Xiuqing Meng",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Shengxue Yang",
                "org": "Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China"
            },
            {
                "name": "Jeffrey Grossman",
                "org": "MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA"
            },
            {
                "name": "Frank D Ogletree",
                "org": "Lawrence Berkeley Natl Lab, Div Mat Sci, Berkeley, CA 94720 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "ADVANCED MATERIALS",
        "year": 2016
    },
    "7nuWtizC": {
        "id": "7nuWtizC",
        "title": "Prevalence and determinants of metabolic syndrome-identified by three criteria among men in rural China: A population-based cross-sectional study conducted during 2007-2008",
        "abstract": "The aim of this study was to estimate MS prevalence according to three criteria and its risk factors among men in rural China.",
        "keywords": [
            "Metabolic syndrome",
            " prevalence",
            " risk factors",
            " protective role",
            " rural areas"
        ],
        "authors": [
            {
                "name": "yueping liu",
                "org": "nantong university"
            },
            {
                "name": "jianxin huang",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "g xu",
                "org": "nantong university"
            },
            {
                "name": "seokwun he",
                "org": "nantong university"
            },
            {
                "name": "jingsong zhang",
                "org": "nantong university"
            },
            {
                "name": "xiaoli wang",
                "org": "nantong university"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "yi shen",
                "org": "nantong university"
            }
        ],
        "venue": "The journal of nutrition, health & aging",
        "year": 2015
    },
    "tWJ1zQYl": {
        "id": "tWJ1zQYl",
        "title": "Generation, Transport and Imaging of Pure Valley Currents in van der Waals Heterostructures",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chenhao Jin",
                "org": ""
            },
            {
                "name": "Jonghwan Kim",
                "org": ""
            },
            {
                "name": "Iqbal Utama",
                "org": ""
            },
            {
                "name": "Emma Regan",
                "org": ""
            },
            {
                "name": "Hans Kleemann",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yuxia Shen",
                "org": ""
            },
            {
                "name": "Matthew Shinner",
                "org": ""
            },
            {
                "name": "Arjun Sengupta",
                "org": ""
            },
            {
                "name": "Kenji Watanabe",
                "org": ""
            },
            {
                "name": "Takashi Taniguchi",
                "org": ""
            },
            {
                "name": "Sefaattin Tongay",
                "org": ""
            },
            {
                "name": "Alex Zettl",
                "org": ""
            },
            {
                "name": "Feng Wang",
                "org": ""
            }
        ],
        "venue": "Bulletin of the American Physical Society",
        "year": 2018
    },
    "B7rs4myJ": {
        "id": "B7rs4myJ",
        "title": "Genetic polymorphisms in obesity-related genes and endometrial cancer risk.",
        "abstract": "BACKGROUND: Obesity is associated with circulating levels of adiponectin and leptin and endometrial cancer risk. Little is known about whether single nucleotide polymorphisms (SNPs) in the genes that encode adiponectin (ADIPOQ), leptin (LEP), adiponectin receptor 1 (ADIPOR1), adiponectin receptor 2 (ADIPOR2), and leptin receptor (LEPR) are associated with endometrial cancer. METHODS: The authors selected 87 tagging SNPs to capture common genetic variants in these 5 genes. These SNPs were evaluated in 1028 endometrial cancer cases and 1932 community controls recruited from Chinese women. Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs). RESULTS: Three of the 10 SNPs evaluated in the ADIPOQ gene were significantly associated with reduced cancer risk. The OR for women homozygous for the minor allele (A/A) for rs3774262 was 0.68 (95% CI, 0.48-0.97) compared with women homozygous for the major allele (G/G). Similar results were found for SNPs rs1063539 and rs12629945 in ADIPOQ, which were in linkage disequilibrium with rs3774262. These associations became nonsignificant after Bonferroni correction was applied. Controls with the minor allele A at rs3774262 had lower weight, smaller waist and hip circumferences, and lower body mass index than controls with the major allele G (all P < .05). Women homozygous for the minor allele (T/T) of rs2071045 in the LEP gene also had significantly lower risk (OR, 0.70; 95% CI, 0.54-0.90) than women homozygous for the major allele (C/C). No other SNPs in the LEP, ADIPOR1, ADIPOR2, or LEPR genes were found to be associated with cancer risk. CONCLUSIONS: Although a chance finding cannot be ruled out, the consistency of findings for gene-endometrial cancer risk and gene-obesity measurements suggests that genetic polymorphisms in the ADIPOQ gene may play a role in endometrial cancer development. Cancer 2011. (c) 2011 American Cancer Society.",
        "keywords": [
            "adipokine",
            "adiponectin",
            "leptin",
            "polymorphism",
            "obesity",
            "endometrial cancer"
        ],
        "authors": [
            {
                "name": "Xiaoli Chen",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Ji-Rong Long",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Jiarong Cheng",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wanqing Wen",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            }
        ],
        "venue": "CANCER",
        "year": 2012
    },
    "84jhMW4R": {
        "id": "84jhMW4R",
        "title": "Prediction Formula of Leachate Generation in Domestic Waste Sanitary Landfill Sites",
        "abstract": "Prediction formula of leachate average generation every year was put forward by analyzing different channels of leachate generation from domestic waste landfill sites.The reliability of prediction formula was assessed by comparing with the leachate generation predicted by the formula and the leachate actual generation in engineering projects.",
        "keywords": [
            "leachate output",
            "reliability",
            "prediction of average generation every year",
            "prediction",
            "sanitary landfill site",
            "domestic waste"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": "China Urban Construction Design & Research Institute,Beijing "
            },
            {
                "name": "Xiong Xiangyang",
                "org": "China Urban Construction Design & Research Institute,Beijing "
            },
            {
                "name": "Chen Gang",
                "org": "China Urban Construction Design & Research Institute,Beijing "
            },
            {
                "name": "Tang Shujuan",
                "org": "China Urban Construction Design & Research Institute,Beijing "
            }
        ],
        "venue": "Environmental Sanitation Engineering",
        "year": 2011
    },
    "fxnKogwt": {
        "id": "fxnKogwt",
        "title": "A prospective study of dietary patterns and mortality in Chinese women.",
        "abstract": "Background: Many foods and nutrients have been suggested to influence life expectancy. However, previous studies have not examined the relationship between dietary patterns and cause-specific mortality. Our study prospectively examines the relationship of dietary patterns with total mortality and cause-specific mortality in a population-based cohort study of Chinese women. Methods: The Shanghai Women's Health Study is a population-based cohort study of 74,942 women age 40 to 70 years at the time of recruitment (September 1996 to May 2000). Detailed dietary information was collected using a validated, quantitative food frequency questionnaire. The cohort has been followed using a combination of in-person interviews and record linkage with various registries. Dietary patterns, derived from principal component analysis, were examined for their relation to total mortality and cause-specific mortality using Cox regression models. Results: After an average of 5.7 years of follow-up (423,717 person-years of observation), there were 1565 deaths. We derived 3 major dietary patterns (vegetable-rich, fruit-rich, and meat-rich). The adjusted hazard ratios for the fruit-rich diet were 0.94 (95% CI = 0.89-0.98) for all causes of death and 0.89 (0.81-0.99), 0.79 (0.69-0.91), and 0.51 (0.39-0.65) for death caused by cardiovascular disease, stroke, and diabetes, respectively. The meat-rich diet was associated with increased risk of diabetes (HR = 1.18; 95% CI = 0.98-1.42) and a slightly elevated risk of total mortality. Conclusion: In general, a fruit-rich diet was related to lower mortality, whereas a meat-rich diet appeared to increase the probability of death.",
        "keywords": [
            "prospective study"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "EPIDEMIOLOGY",
        "year": 2007
    },
    "9kHY5p6m": {
        "id": "9kHY5p6m",
        "title": "Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality.",
        "abstract": "Background: Asian populations habitually consume a large amount of cruciferous vegetables and other plant-based foods. Few epidemiologic investigations have evaluated the potential health effects of these foods in Asian populations. Objective: We aimed to examine the associations of cruciferous vegetables, noncruciferous vegetables, total vegetables, and total fruit intake with risk of all-cause and cause-specific mortality. Design: The analysis included 134,796 Chinese adults who participated in 2 population-based, prospective cohort studies: the Shanghai Women's Health Study and the Shanghai Men's Health Study. Dietary intakes were assessed at baseline through in-person interviews by using validated food-frequency questionnaires. Deaths were ascertained by biennial home visits and linkage with vital statistics registries. Results: We identified 3442 deaths among women during a mean follow-up of 10.2 y and 1951 deaths among men during a mean follow-up of 4.6 y. Overall, fruit and vegetable intake was inversely associated with risk of total mortality in both women and men, and a dose-response pattern was particularly evident for cruciferous vegetable intake. The pooled multivariate hazard ratios (95% CIs) for total mortality across increasing quintiles of intake were 1 (reference), 0.91 (0.84, 0.98), 0.88 (0.77, 1.00), 0.85 (0.76, 0.96), and 0.78 (0.71, 0.85) for cruciferous vegetables (P < 0.0001 for trend) and 0.88 (0.79, 0.97), 0.88 (0.79, 0.98), 0.76 (0.62, 0.92), and 0.84 (0.69, 1.00) for total vegetables (P = 0.03 for trend). The inverse associations were primarily related to cardiovascular disease mortality but not to cancer mortality. Conclusion: Our findings support recommendations to increase consumption of vegetables, particularly cruciferous vegetables, and fruit to promote cardiovascular health and overall longevity. Am J Clin Nutr 2011;94:240-6.",
        "keywords": [],
        "authors": [
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med,Sch Med,IMPH, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "AMERICAN JOURNAL OF CLINICAL NUTRITION",
        "year": 2011
    },
    "Fxlx5OVW": {
        "id": "Fxlx5OVW",
        "title": "Endostatin Polymorphism 4349G/A(D104N) Is Not Associated with Aggressiveness of Disease in Prostate Cancer (Erratum)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "bo lu",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "ming teng",
                "org": ""
            },
            {
                "name": "z f wang",
                "org": ""
            },
            {
                "name": "carolyn cao",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "eric t shinohara",
                "org": ""
            },
            {
                "name": "q y cai",
                "org": ""
            },
            {
                "name": "he cheng li",
                "org": ""
            }
        ],
        "venue": "Disease Markers",
        "year": 2005
    },
    "uiDqwuWA": {
        "id": "uiDqwuWA",
        "title": "Synthesis of Highly Anisotropic Semiconducting GaTe Nanomaterials and Emerging Properties Enabled by Epitaxy.",
        "abstract": "Bulk nacre-like composites with mineral nano-interconnectivity at the same length scale as in the biological material are produced using magnetic alignment and selective sintering techniques. These materials display stiffness and strength levels comparable to that of continuous fiber composites with the advantage of easier processability inherent of discontinuous composites. This opens new possibilities to produce parts with more complex designs.",
        "keywords": [
            "gallium telluride",
            "physical vapor transport",
            "pseudo-1D materials"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Gang Wang",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Emmanuel Soignard",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Afsaneh Khosravi",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Marco Manca",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Xavier Marie",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Shery L Y Chang",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bernhard Urbaszek",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "ADVANCED MATERIALS",
        "year": 2017
    },
    "wp72qbto": {
        "id": "wp72qbto",
        "title": "Major metabolite of F2-isoprostane in urine may be a more sensitive biomarker of oxidative stress than isoprostane itself.",
        "abstract": "Background: There is limited literature on the contributors to isoprostane metabolite 2,3-dinor-5,6-dihydro-15-F-2t-isoprostane (15-F-2t-IsoP-M) compared with F-2-isoprostanes (F-2-IsoPs) as an oxidative stress biomarker. Objective: The objective of this study was to investigate whether plasma concentrations of antioxidants, urinary excretion rates of polyphenols, and antioxidants in food and dietary supplements are attributable to both urinary F-2-IsoP and 15-F-2t-IsoP-M concentrations. Design: Dietary intake information and blood and urine samples were obtained from 845 healthy middle-aged and elderly female participants of the Shanghai Women's Health Study. Urinary isoprostanes (F-2-IsoPs and 15-F-2t-IsoP-M) were measured and adjusted for creatinine concentrations. Results: Urinary 15-F-2t-IsoP-M and F-2-IsoP concentrations were lower in subjects who used a multivitamin. Lower F-2-IsoP concentrations were observed in ginseng users, whereas lower concentrations of 15-F-2t-IsoP-M were shown in subjects who used a vitamin E supplement. Plasma concentrations of several antioxidants (ie, beta-carotenes, both trans and cis beta-carotenes, lycopene other than trans, 5-cis and 7-cis isomers, cis anhydrolutein, and cis beta-cryptoxanthin) were inversely associated with 15-F-2t-IsoP-M but not with F-2-IsoPs, whereas beta-, gamma-, and delta-tocopherols were positively associated with 15-F-2t-IsoP-M but not with F-2-IsoPs. Urinary polyphenol quercetin was positively associated with both F-2-IsoPs and 15-F-2t-IsoP-M. Conclusion: The results suggest that the F-2-IsoP major metabolite 15-F-2t-IsoP-M may be a more sensitive marker of endogenous oxidative stress status than are F-2-IsoPs in the assessment of effects of antioxidants on age-related diseases. Am J Clin Nutr 2012;96:405-14.",
        "keywords": [
            "polyphenols",
            "tea",
            "linear models",
            "cross sectional studies"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA"
            },
            {
                "name": "Xiao-ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Xinqing Deng",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Adrian Franke",
                "org": "Univ Hawaii, Canc Res Ctr Hawaii, Honolulu, HI 96813 USA"
            },
            {
                "name": "L Jackson Roberts",
                "org": "Vanderbilt Univ, Sch Med, Dept Pharmacol, Nashville, TN 37212 USA"
            },
            {
                "name": "Ginger Milne",
                "org": "Vanderbilt Univ, Sch Med, Div Clin Pharmacol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Nashville, TN 37212 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF CLINICAL NUTRITION",
        "year": 2012
    },
    "SHGPfB9w": {
        "id": "SHGPfB9w",
        "title": "Exciton pumping across type-I gallium chalcogenide heterojunctions.",
        "abstract": "Quasi-two-dimensional gallium chalcogenide heterostructures are created by transferring exfoliated few-layer GaSe onto bulk GaTe sheets. Luminescence spectroscopy measurements reveal that the light emission from underlying GaTe layers drastically increases on heterojunction regions where GaSe layers make contact with the GaTe. Density functional theory (DFT) and band offset calculations show that conduction band minimum (CBM) (valance band maximum (VBM)) values of GaSe are higher (lower) in energy compared to GaTe, forming type-I band alignment at the interface. Consequently, GaSe layers provide photo-excited electrons and holes to GaTe sheets through relatively large built-in potential at the interface, increasing overall exciton population and light emission from GaTe. Observed results are not specific to the GaSe/GaTe system but observed on GaS/GaSe heterolayers with type-I band alignment. Observed experimental findings and theoretical studies provide unique insights into interface effects across dissimilar gallium chalcogenides and offer new ways to boost optical performance by simple epitaxial coating.",
        "keywords": [
            "heterojunctions",
            "2D materials",
            "gallium chalcogenides",
            "atomically thin layers",
            "optics"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Jun Kang",
                "org": "Univ Antwerp, Dept Phys, B-2610 Antwerp, Belgium"
            },
            {
                "name": "Hasan Sahin",
                "org": "Univ Antwerp, Dept Phys, B-2610 Antwerp, Belgium"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Aslihan Suslu",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Kedi Wu",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Francois Peeters",
                "org": "Univ Antwerp, Dept Phys, B-2610 Antwerp, Belgium"
            },
            {
                "name": "Xiuqing Meng",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Mat Sci & Engn, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "NANOTECHNOLOGY",
        "year": 2016
    },
    "BKoFmqi4": {
        "id": "BKoFmqi4",
        "title": "Opera Crosswove Puaales",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2011
    },
    "hl6idSTk": {
        "id": "hl6idSTk",
        "title": "Bruch's Membrane Aging Reduces CD46 Expression and Enhances VEGF Secretion in RPE: Implications for Age-related Macular Degeneration",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "m a fields",
                "org": "medical university of south carolina"
            },
            {
                "name": "hui cai",
                "org": "columbia university"
            },
            {
                "name": "hannah e bowrey",
                "org": "medical university of south carolina"
            },
            {
                "name": "ernesto f moreira",
                "org": "medical university of south carolina"
            },
            {
                "name": "kannan kunchithapautham",
                "org": "medical university of south carolina"
            },
            {
                "name": "jie gong",
                "org": "medical university of south carolina"
            },
            {
                "name": "lucian del priore",
                "org": "medical university of south carolina"
            }
        ],
        "venue": "Investigative Ophthalmology & Visual Science",
        "year": 2015
    },
    "kKDxKesR": {
        "id": "kKDxKesR",
        "title": "Passivation of Layered Gallium Telluride by Double Encapsulation with Graphene.",
        "abstract": "Layered semiconductor gallium telluride (GaTe) undergoes a rapid structural transition to a degraded phase in ambient conditions, limiting its utility in devices such as optical switches. In this work, we demonstrate that the degradation process in GaTe flakes can be slowed down dramatically via encapsulation with graphene. Through examining Raman signatures of degradation, we show that the choice of substrate significantly impacts the degradation rate and that the process is accelerated by the transfer of GaTe to hydrophilic substrates such as SiO/Si. We find that double encapsulation with both top and bottom graphene layers can extend the lifetime of the material for several weeks. The photoresponse of flakes encapsulated in this way is only reduced by 17.6 ± 0.4% after 2 weeks, whereas unencapsulated flakes display no response after this time. Our results demonstrate the potential for alternative, van der Waals material-based passivation strategies in unstable layered materials and highlight the need for careful selection of substrates for 2D electronic devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Elisha Mercado",
                "org": "Center for Device Thermography and Reliability (CDTR), H. H. Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K."
            },
            {
                "name": "Yan Zhou",
                "org": "Center for Device Thermography and Reliability (CDTR), H. H. Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K."
            },
            {
                "name": "Yong Xie",
                "org": "School of Advanced Materials and Nanotechnology, Key Laboratory of Wide Band-Gap Semiconductor Materials and Devices, Xidian University, Xi'an 710071, P. R. China."
            },
            {
                "name": "Qinghua Zhao",
                "org": "State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi'an 710072, P. R. China."
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona 85287, United States."
            },
            {
                "name": "Bin Chen",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona 85287, United States."
            },
            {
                "name": "Wanqi Jie",
                "org": "State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi'an 710072, P. R. China."
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona 85287, United States."
            },
            {
                "name": "Tao Wang",
                "org": "State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi'an 710072, P. R. China."
            },
            {
                "name": "Martin Kuball",
                "org": "Center for Device Thermography and Reliability (CDTR), H. H. Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K."
            }
        ],
        "venue": "ACS omega",
        "year": 2019
    },
    "yRkXBFpT": {
        "id": "yRkXBFpT",
        "title": "Influence of Total Flavonoids of Epimedium on Adiponectin Receptors Expression in Hyperlipidemia Rats",
        "abstract": "Aim To investigate the influence of total flavonoids of epimedium on adiponectin receptors expression in hyperlipidemia rats and the mechanism of protection in hyperlipidemia rats. Methods 35 male SD rats were randomly divided into two groups: high cholesterol diet group(n=26) and control group(n=9).Rats of high-fat diet group were fed with high-fat diet for 12 weeks,then 26 SD male rats were randomly divided into three groups: model group,high hyperlipidemia group with low dose total flavonoids of epimedium(100 mg/kg) group,hyperlipidemia group with high dose total flavonoids of epimedium(200 mg/kg) group.Serum lipid levels of all rats were measured and the aorta was taken for pathologic analysis.Serum adiponectin was detected by ELISA.The expression of both adiponectin receptor 1(AdipoR1) and adiponectin receptor 2(AdipoR2) on the aorta were analyzed by realtime PCR and Western boltting. Results After 12 weeks of feeding,as compared with full diet group,the levels of triglyceride(TG),total cholesterol(TC) and low density lipoprotein cholesterol(LDLC) in high cholesterol diet groups were significantly increased(P<0.01),which indicated that the hyperlipidemia model was estimated.After 4 weeks' treatment,as compared with high hyperlipidemia model group,the levels of TC,TG in total flavonoids of epimedium groups were obviously lower(P<0.05 or 0.01).Aortic intimal hyperplasia and smooth muscle cells proliferation in rats fed with high cholesterol diet were decreased in high hyperlipidemia with total flavonoids of epimedium groups.As compared with high hyperlipidemia model group,the serum levels of adiponectin with total flavonoids of epimedium were increased(P<0.05),moreover,these changes were more significant in high dose treated group(P<0.05),and the expression of both AdipoR1 mRNA and AdipoR2 mRNA were significantly increased(P<0.05 or 0.01),moreover,the expression of AdipoR1 mRNA were significant in high dose treated group.The expression levels of both AdipoR1 and AdipoR2 protein in total flavonoids of epimedium group were significantly higher than that of hyperlipidemia model group. Conclusion Total flavonoids of epimedium can reduce the levels of serum lipids,but increase the levels of serum adiponectin and the mRNA and protein expression of both AdipoR1 and AdipoR2 on the aorta in hyperlipidemia rats.",
        "keywords": [
            "Adiponectin Receptor",
            "Hyperlipidemia",
            "Adiponectin",
            "Total Flavonoids of Epimedium"
        ],
        "authors": [
            {
                "name": "XU Yu-Shun",
                "org": "School of Clincal Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu ,China"
            },
            {
                "name": "SHEN Si-Yu",
                "org": "School of Clincal Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "School of Clincal Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-Ming",
                "org": "School of Clincal Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Chinese Journal of Arteriosclerosis",
        "year": 2010
    },
    "oMEfNdCV": {
        "id": "oMEfNdCV",
        "title": "Triamino pyrimidines and pyridines as histamine H4 receptor modulators",
        "abstract": "Two series of triamino pyrimidines and a series of triamino pyridines have been synthesized and their structure–activity relationships evaluated for activity at the H4 receptor in competitive binding and functional assays. Small structural changes in these three hetereoaromatic cores influenced the functional activity of these compounds.",
        "keywords": [
            "Pyrimidine",
            "Pyridine",
            "Histamine",
            "Histamine H4",
            "Antagonist"
        ],
        "authors": [
            {
                "name": "Steven P. Meduna",
                "org": "Corresponding author."
            },
            {
                "name": "Brad M. Savall",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Hui Cai",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "James P. Edwards",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Robin L. Thurmond",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Patricia M. McGovern",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            }
        ],
        "venue": "Bioorganic & Medicinal Chemistry Letters",
        "year": 2011
    },
    "pRaqoTUW": {
        "id": "pRaqoTUW",
        "title": "Cognition of the substance of modernization trend of traditional Chinese medicine from the angle of phenomenological theory",
        "abstract": "AIM: To realize the substance of modernization trend of Chinese medicine. METHODS: From several aspects included the entirety,the nature of differentiation,the direct-viewing part and the substance of phenomenological theory of Chinese medicine etc. to realize the substance of modernization trend of Chinese medicine. RESULTS: From the entirety of phenomenological theory of Chinese medicine to grasp the regional part of the microcosmic object; From the nature of differentiation of phenomenological theory of Chinese medicine to grasp the concept of modern medicine disease; From the direct-viewing part of phenomenological theory of Chinese medicine to grasp the logic; From the substance of phenomenological theory of Chinese medicine,\"symptom\", should make great efforts in micro-analysis and complex symmetry to find out the breakthrough which were of the important aspects to grasp the modernization trend of Chinese medicine correctly.CONCLUSION: It has important realistic significance to realize the substance of modernization trend of Chinese medicine from the angle of phenomenological theory for the modernization of Chinese medicine.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ", Department of Integrated Traditional Chinese Medicine and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            }
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005
    },
    "jBn71WAK": {
        "id": "jBn71WAK",
        "title": "Atherosclerosis and Rheumatoid Arthritis are \"Different Diseases Tongzheng\" to Follow Oxidized Low Density Lipoprotein",
        "abstract": "Atherosclerosis(AS)belongs to \"stagnant blood\"or\"phlegm\" according to clinical manifestation,and rheumatoid arthritis(RA)belongs to \"arthralgia zheng\".They are \"Different Diseases\" according to diagnosis of traditional chinese medicine and west medicine.According to pathogenesis of traditional chinese medicine,they are relevant to\"stagnant blood cause phlegm,stagnant blood and phlegm interties gradually\",and they have \"Tongzheng\" such as \"stagnant blood and phlegm interties \".AS is close relevant to immune inflammatory reaction.Oxidized low density lipoprotein(ox-LDL),ox-LDL antibody and low density lipoprotein-immune complexes(LDL-IC) all play important roles in AS.More and more cadiovascular events of RA are relevant to AS rapid expansion.Lipids profile of RA are causing AS above all combined cadiovascular diseases,such as high levels Ox-LDL,MDA-LDL and LDL-IC,and LDL is more susceptible to oxidative.Ox-LDL could be as one of \"Different Diseases Tongzheng\" index about AS and RA.To monitor ox-LDL,ox-LDL antibody and LDL-IC are helpful to better evaluate and treat RA.",
        "keywords": [
            "rheumatoid arthritis",
            "oxidized low density lipoprotein",
            "atherosclerosis"
        ],
        "authors": [
            {
                "name": "YAO Ru-Bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2011
    },
    "cO8kXIy6": {
        "id": "cO8kXIy6",
        "title": "Fish intake and risks of total and cause-specific mortality in 2 population-based cohort studies of 134,296 men and women.",
        "abstract": "Despite a proposed protective effect of fish intake on the risk of cardiovascular disease, epidemiologic evidence on fish intake and mortality is inconsistent. We investigated associations of fish intake, assessed through a validated food frequency questionnaire, with risks of total and cause-specific mortality in 2 prospective cohort studies of 134,296 Chinese men and women (1997-2009). Vital status and date and cause of death were ascertained through annual linkage to the Shanghai Vital Statistics Registry database and biennial home visits. Cox regression was used to calculate hazard ratios and corresponding 95% confidence intervals. After excluding the first year of observation, the analysis included 3,666 deaths among women and 2,170 deaths among men. Fish intake was inversely associated with risks of total, ischemic stroke, and diabetes mortality; the corresponding hazard ratios for the highest quintiles of intake compared with the lowest were 0.84 (95% confidence interval (CI): 0.76, 0.92), 0.63 (95% CI: 0.41, 0.94), and 0.61 (95% CI: 0.39, 0.95), respectively. No associations with cancer or ischemic heart disease mortality were observed. Further analyses suggested that the inverse associations with total, ischemic stroke, and diabetes mortality were primarily related to consumption of saltwater fish and intake of long-chain n-3 fatty acids. Overall, our findings support the postulated health benefits of fish consumption.",
        "keywords": [
            "women",
            "diet",
            "stroke",
            "China",
            "men",
            "china",
            "mortality",
            "fish intake"
        ],
        "authors": [
            {
                "name": "Yumie Takata",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xianglan Zhang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Gong Yang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Jing Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "VA Medical Center(),,"
            }
        ],
        "venue": "American journal of epidemiology",
        "year": 2013
    },
    "gaJ6BcSC": {
        "id": "gaJ6BcSC",
        "title": "Associations of obesity and weight change with physical and mental impairments in elderly Chinese people.",
        "abstract": "•Obesity at or after middle age and weight gain during adulthood are associated with accelerated age-related functional impairments.•Being underweight after age 70 is also associated with higher probabilities of functional decline.",
        "keywords": [
            "Function impairments",
            "Body mass index",
            "Weight gain",
            "Fat distribution",
            "Chinese"
        ],
        "authors": [
            {
                "name": "Jingjing Zhu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Ave., Nashville, TN, 37203, USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200031, China"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Ave., Nashville, TN, 37203, USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200031, China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200031, China"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Ave., Nashville, TN, 37203, USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, 2525 West End Ave., Nashville, TN, 37203, USA"
            }
        ],
        "venue": "Maturitas",
        "year": 2018
    },
    "LEnIUjt7": {
        "id": "LEnIUjt7",
        "title": "The expression of matrix metalloproteinase-3 in rheumatoid arthritis",
        "abstract": "Rheumatoid arthritis(RA) is an autoimmune disorder characterized by chronic synovitis and progressive joint destruction,which the pathogenesis hasn't been cleared.The early characteristics of rheumatoid joints include neovascularization and proliferation of synovial tissue,and eventual resorption of bone is due to the action of osteoclasts.MMPs are a family of zinc-dependent proteolytic enzymes that have the ability to degrade almost all proteins of the extracellular matrix.The levels of MMP-3 in the serum of RA patients have been thought to play a pivotal role in cartilage degradation.It would be valuable to have a marker that could be an indicator of joint damage progression,especially in the early stage of RA.It has also been used as a marker for the effectiveness of antirheumatic therapy.So we approached the structure,function,expression and regulation of MMP-3 expecting to expound the etiopathogenesis of RA.",
        "keywords": [
            "Expression and regulation",
            "Rheumatoid arthritis",
            "Structure",
            "Matrix metalloproteinase-3"
        ],
        "authors": [
            {
                "name": "DONG Xiaolei",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHANG Qunyan",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "Cai Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Osteoporosis",
        "year": 2010
    },
    "ZEcZhYLv": {
        "id": "ZEcZhYLv",
        "title": "[Tight junction protein expression of gastric mucosa and its significance in children with Helicobacter pylori infection].",
        "abstract": "Our results revealed that the tight junction protein E-cadherin, β-catenin, ZO-1 expression of gastric mucosa were decreased in children with Hp infection, while claudin-4 expression was increased in Hp positive patients with peptic ulcer, suggesting that damage to gastric epithelial barrier function may be the main pathogenesis of Hp associated gastric diseases in children.",
        "keywords": [],
        "authors": [
            {
                "name": "wei li",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "wei gu",
                "org": ""
            },
            {
                "name": "k peng",
                "org": ""
            },
            {
                "name": "h cai",
                "org": ""
            },
            {
                "name": "ling jiang",
                "org": ""
            },
            {
                "name": "ming jiang",
                "org": ""
            }
        ],
        "venue": "Zhonghua er ke za zhi = Chinese journal of pediatrics",
        "year": 2015
    },
    "9jPdaJQ5": {
        "id": "9jPdaJQ5",
        "title": "Effects of high intensity focused ultrasound combined with ultrasound contrast agent on hydatid cysts in vitro",
        "abstract": "The aim is to evaluate the efficacy of high intensity focused ultrasound(HIFU) combined with ultrasound contrast agent(UCA) on hydatid cysts of Echinococcus granulosus in vitro,and to obtain a better method of HIFU which would be used to kill the cysts.One hundred and fifty fresh cysts were divided into 6 groups according to the diameters of cysts,and every group was received following treatments respectively: Group A(blank control) without HIFU treatment;Group B treated with 0.1 mL UCA only;Group C treated with HIFU only;Group D treated with 0.1 mL UCA and HIFU;Group E treated with 0.2 mL UCA and HIFU.During the irradiation of HIFU,the changes of ultrasonic gray scale of the cysts were recorded accordingly,and the instant death rates of protoscoleces were determined from the hydatid fluids.It was demonstrated that the changes of ultrasonic gray scale and the instant death rate of protoscoleces treated with UCA and HIFU were significant than those in the groups treated with HIFU only,or UCA only,and the changes were obvious in the groups treated with the increase of UCA.Those results suggest that UCA could enhance the killing efficacy of HIFU on hydatid cyst in vitro.",
        "keywords": [
            "hydatid",
            "ultrasound contrast agent",
            "high intensity focused ultrasound(HIFU)",
            "Echinococcus granulosus",
            "protoscolex"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecule Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "YE Bin",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecule Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "ZHAO Yi-feng",
                "org": "Qinghai University Affiliated Hospital,Xining ,China"
            },
            {
                "name": "GUO Ying-xing",
                "org": "Qinghai University Affiliated Hospital,Xining ,China"
            },
            {
                "name": "HAN Xiu-min",
                "org": "Qinghai Institute for Endemic Disease Control,Xining ,China"
            },
            {
                "name": "ZHANG Cheng-wu",
                "org": "Qinghai University Affiliated Hospital,Xining ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2012
    },
    "ZBeHFBh2": {
        "id": "ZBeHFBh2",
        "title": "Abstract 1020: Combined effects of BCL-2 pathway gene variants on the risk of endometrial cancer: results from Shanghai Endometrial Cancer Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "jiarong cheng",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "qiuyn cai",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "jirong long",
                "org": ""
            },
            {
                "name": "tsogzolmaa dorjgochoo",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2010
    },
    "4Xd4G57O": {
        "id": "4Xd4G57O",
        "title": "Improvement of Tanshinone ⅡA on Myocardial Fibrosis in Rats with Pressure Overload",
        "abstract": "Objective: To observe the improvement of tanshinone ⅡA (TanⅡA) on myocardial fibrosis in rats with pressure overload. Method: 60 Sprague-Dawley (SD) rats were randomly divided into sham operation group (sham group,n=8) and surgical group (n=52). The rats of surgical group induced by the abdominal aorta constriction preparation. 32 rats of surgical group survived and were randomly divided into four groups (n=8):model group, TanⅡA low dose group (L-TanⅡA group), TanⅡA high dose group (H-TanⅡA group) and positive captopril group (captopril group). After 4 weeks, heart mass indexes were estimated, in concurrent evaluation of myocardial histology, as well as myocardial hydroxyproline content by ELISA, and immunohistochemistry staining for myocardial ROCK1, transforming growth factor-beta1 (TGF-β1) and nuclear transcription factor-kappa B p65 (NF-κB p65) protein content. Results: Compared with those in sham group, heart mass indexes, myocardial hydroxyproline content and myocardial ROCK1, TGF-β1 and NF-κB p65 content were increased in the model group (P<0.01); Compared with those in model group, heart mass indexes, myocardial hydroxyproline content and myocardial ROCK1, TGF-β1 and NF-κB p65 content were decreased in the L-TanⅡA group (P<0.05 or P<0.01), while these indexes were decreased significantly in the H-Tan Ⅱ A group (P<0.01). Conclusion: TanⅡA can improve myocardial fibrosis in rats with pressure overload and this effect may be related to inhibition of ROCK1 expression, downregulation of TGF-β1 and NF-κB p65 expression.",
        "keywords": [
            "Rat",
            "NF-κB p65",
            "Myocardial fibrosis",
            "ROCK1",
            "Pressure overload",
            "TanshinoneⅡA",
            "TGF-β1"
        ],
        "authors": [
            {
                "name": "Chang Wenjing",
                "org": ""
            },
            {
                "name": "Zhao Zhiming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing Gerenal Hospital of Nanjing Military Command, PLA,Nanjing ,China"
            },
            {
                "name": "Zhao Lingjie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing Gerenal Hospital of Nanjing Military Command, PLA,Nanjing ,China"
            },
            {
                "name": "Dong Xiaolei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing Gerenal Hospital of Nanjing Military Command, PLA,Nanjing ,China"
            },
            {
                "name": "Cai Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing Gerenal Hospital of Nanjing Military Command, PLA,Nanjing ,China; /1First Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2013
    },
    "BsJaia7U": {
        "id": "BsJaia7U",
        "title": "Changes of the level of plasma endothelin and calcitonin gene-related peptide in rats with pressure overload",
        "abstract": "Objective To observe the changes of plasma endothelin and calcitonin gene-related peptide(CGRP)in rats with pressure overload,and to study the possible mechanism of left ventricular remodeling.Methods Left ventricular mass index(LVMI)and plasma endothelin(ET)and calcitonin gene-related peptide were measured in the rat model with myocardial hypertrophy of congestive heart failure and pressure overload by abdominal aortic constriction by radioimmunoassay.Results ①The plasma endothelin levels in the model group were obviously higher than those of sham group(P<0.01),LVMI in model group was higher than that in sham operation group(P<0.05),positively related to level of plasma ET.②The level of plasma CGRP in model group was lower significantly than that in sham operation group(P<0.01),and negatively related to LVMI.③Plasma ET/CGRP ratio was less than 1 in normal control group obviously,close to 1 in model group,positively related to LVH.Conclusion The levels of plasma ET and CGRP were related to LVH.The mechanism of heart failure might be related with the disorganization of ET and CGRP levels in plasma so as the left ventricular hypertrophy.",
        "keywords": [
            "Calcitonin gene-related peptide",
            "Ventricular remodeling",
            "left ventricular",
            "Hypertrophy"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            },
            {
                "name": "ZHANG Yong-wen",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": ". Nanjing General Hospital of Nanjing Area Command,Jiangsu 21002,China"
            }
        ],
        "venue": "Shanxi Medical Journal",
        "year": 2009
    },
    "QCi5COSC": {
        "id": "QCi5COSC",
        "title": "Candidate gene polymorphisms of primary osteoporosis",
        "abstract": "OBJECTIVE: To review and summarize the current advance in the candidate gene polymorphisms of osteoporosis.DATA SOURCES: An online search of Medline database was undertaken by using theof\"osteoporosis, candidate gene, polymorphism, vitamin D receptor gene, estrogen receptor gene, insulin-like growth factor gene, IL-6 gene, transforming growth factor beta gene, calcitonin receptor gene, COLIA gene\"to identify the articles about osteoporosis published in English from January 1998 to May 2004.STUDY SELECTION: The articles about the relationship between osteoporosis and candidate gene polymorphisms were selected after first trial. Some articles obviously lacking of randomized controlled trial were eliminated. The rest full texts were obtained, excluding reviews.DATA EXTRACTION: Totally 197 accorded articles were collected, and 27 related ones were selected according to the new views about the relationship between candidate genes and osteoporosis. Of the 170 excluded ones, 105 were non-randomized or repetitive studies, and the other 65 were reviews.DATA SYNTHESIS: The data of the selected articles were concluded. The studies of the relationship between candidate genes and osteoporosis in etiology and pathogenesis were summarized and evaluated. Many candidate genes participate in regulating primary osteoporosis. It is unknown which are the major genes to result in osteoporosis. However, it is certain that genes play important roles in etiology, which contribute to bone mineral density and peak bone mass, etc. CONCLUSION: Many candidate genes polymorphisms, such as vitamin D receptor gene, estrogen receptor gene, insulin-like growth factor gene etc., are relevant to bone mineral density, peak bone mass, bone stiffness index, the rate to fracture and so on. It was showed that gene polymorphisms play a crucial role in osteoporosis.",
        "keywords": [],
        "authors": [
            {
                "name": "Xiu Chun-ying",
                "org": ", Department of Integrated Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Guo Jun-hao",
                "org": ", Department of Integrated Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Cai Hui",
                "org": ", Department of Integrated Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            }
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005
    },
    "Dewvaue8": {
        "id": "Dewvaue8",
        "title": "The effect of curcumin on adjuvant arthritis in rats",
        "abstract": "Objective To explore the effects of curcumin on the pathological changes in synovium of adjuvant arthritis(AA) rats.Methods SD rats were divided into three groups(n=10 each): normal rat control group;AA model control group(induced by giving Freund′s complete adjuvant hypo into the left hind toe);and treatment group(with curcumin 50 mg·kg-1 ip qd administered to the model rats from d9 after AA).The degree of swelling of the toe and knee joint was measured on d7 and d14.The rats were killed on d15 to remove the synovium for histopathologic study and scoring.Results No obvious differences in swelling were found between the model group and the treatment group on d7,but the differences became significant on d14(59.82 vs.30.4,P<0.05).The pathological scores for inflammatory cell infiltration and macrophage infiltration were also lower in the treatment group(P<0.05).Conclusion The effects of curcumin on AA rats include: decreasing manifestations of arthritis,alleviating joint swelling and reducing inflammatory infiltration of synovial tissue.",
        "keywords": [
            "arthrocele",
            "pathomorphology",
            "adjuvant arthritis",
            "empirical study",
            "curcumin"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHENG Zhaoling",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Acta Academiae Medicinae Xuzhou",
        "year": 2008
    },
    "0OqMINCM": {
        "id": "0OqMINCM",
        "title": "Vitamin intake and liver cancer risk: a report from two cohort studies in China.",
        "abstract": "Epidemiologic studies on the relationship between vitamin intake and liver cancer risk are sparse and inconsistent.We evaluated vitamin intake from diet and supplements and risk of liver cancer in 132,837 women and men from China who were recruited into the Shanghai Women's Health Study from 1997 to 2000 or the Shanghai Men's Health Study from 2002 to 2006. In-person interviews, using a validated food-frequency questionnaire, were conducted to collect data on dietary habits. Follow-up consisted of in-person surveys and record linkage. Hazard ratios and 95% confidence intervals were estimated using Cox proportional hazard models with adjustment for potential confounders to compare liver cancer risk among participants with high vs low vitamin intake. All statistical tests were two-sided.After excluding the first 2 years of follow-up, 267 participants (including 118 women and 149 men) developed liver cancer during an average of 10.9 (Shanghai Women's Health Study) or 5.5 (Shanghai Men's Health Study) years of follow-up. Dietary vitamin E intake was inversely associated with liver cancer risk (P(trend) = .01), as was vitamin E supplement use (hazard ratio = 0.52, 95% confidence interval = 0.30 to 0.90). This association was consistent among participants with and without self-reported liver disease or a family history of liver cancer. Vitamin C and multivitamin use was associated with increased risk among participants with self-reported liver disease or family history of liver cancer, whereas intake of vitamin C and other vitamins from dietary sources was unrelated to liver cancer risk.Vitamin E intake, either from diet or supplements, may reduce the risk of liver cancer.",
        "keywords": [
            "questionnaires",
            "odds ratio",
            "proportional hazards models",
            "cohort studies",
            "china",
            "prospective studies"
        ],
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Honglan Li",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Jing Gao",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            }
        ],
        "venue": "Journal of the National Cancer Institute",
        "year": 2012
    },
    "zu5kWMcE": {
        "id": "zu5kWMcE",
        "title": "Changes of nitric oxide in the myocardium of rats with isoproterenol-induced congestive heart failure",
        "abstract": "Objective To investigate the changes of nitric oxide(NO)in the myocardium of rats with isoproterenol(ISO)-induced congestive heart failure(CHF).Methods Fifty male SD rats were randomly allocated into blank control group(n=10)and ISO-induced CHF group(ISO group,n=40).The rats in ISO group were subcutaneously injected with 170 mg/kg ISO for 2 times at a 24 h interval,while the rats in blank control group were given a subcutaneous injection of 0.25 ml normal saline for 2 times at a 24 h interval.At week 6,the left ventricular ejection fraction(LVEF)was measured by echocardiogram.The ISO-induced CHF rats,with an LVEF≤45%,were divided into 2 groups:compensation group(COMP,n=8)and decompensation group(DECOMP,n=14).At week 18,the heart function parameters were detected by echocardiogram,including LVEF,fractional shortening(FS),left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),and ventricular weight index(VWI)and left ventricular weight index(LVWI)was measured after LV morphopathological examination.NO level was detected in the myocardium by enzyme immunoassay method.The pathological changes of myocardium were observed.Results Compared with blank control group,the heart function significantly decreased,VWI,LVWI,pathological scores and NO in the myocardium significantly increased in COMP group(P<0.05)and DECOMP group(P<0.01).Compared with COMP group,the heart function significantly decreased in DECOMP group,VWI,LVWI,pathological scores and NO in the myocardium significantly increased(P<0.01).Conclusion The high dose of isoproterenol can successfully induce the CHF rat model,which may be related to the activation of NO in the myocardium.",
        "keywords": [
            "nitric oxide",
            "SD rats",
            "congestive heart failure",
            "Isoproterenol"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "GUO Han",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "XU Yu-shun",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Dept of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Journal of Shanxi Medical University",
        "year": 2010
    },
    "txA6YErC": {
        "id": "txA6YErC",
        "title": "Green tea consumption and risk of type 2 diabetes in Chinese adults: the Shanghai Women's Health Study and the Shanghai Men's Health Study.",
        "abstract": "Green tea drinking was associated with an increased risk of T2D in Chinese adults. The mechanisms underlying the association need to be elucidated.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaona Liu",
                "org": "Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China."
            },
            {
                "name": "Wanghong Xu",
                "org": "Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China."
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China."
            },
            {
                "name": "Bu-Tian Ji",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA."
            },
            {
                "name": "Xiang Shu",
                "org": "Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Thomas Wang",
                "org": "Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Robert E Gerszten",
                "org": "Division of Cardiovascular Medicine, Beth Israel Deaconess Hospital, Boston, MA, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Shanghai Jiaotong University Renji Hospital, Shanghai, China."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA."
            }
        ],
        "venue": "International journal of epidemiology",
        "year": 2018
    },
    "hgldquqq": {
        "id": "hgldquqq",
        "title": "Abstract B143: Physical activity and risk for breast cancer in postmenopausal Chinese women",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "y t gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "jing gao",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "haonan li",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "charles e matthews",
                "org": ""
            }
        ],
        "venue": "Cancer Prevention Research",
        "year": 2008
    },
    "tUbTAHk9": {
        "id": "tUbTAHk9",
        "title": "Role of LOX-1 in Pioglitazone Regulating Apoptosis Protein in Aorta of Hyperlipidemia Rats",
        "abstract": "Objective:To investigate influence of pioglitazone on the expression of LOX-1 and Bax,Bcl-2 on aorta in hyperlipidemia rats,and also to study the effects of LOX-1.Method:26 male SD rats were randomly divided into control group(n=9) and high-fat diets group(n=17).High-fat diets rats raised for 12 weeks were randomly divided into model group(n=8) and pioglitazone treated group(n=9),respectively gavaged with distilled water and pioglitazone.After 4 weeks,serum lipid level of all rats was measured.LOX-1 and apoptosis protein of Bax,Bcl-2 on the aorta were analyzed by immunohistochemical method.Terminal deoxynucleotidyl acyltransferase-mediated dUTP nick end labeling stained apoptotic cells in aortic intimal area to calculate apoptosis index.Results:After 12 weeks,17 rats raised with high-fat diets were successfully induced hyperlipidemia animal models.Intervention with pioglitazone for 4 weeks,compared with model group,serem levels of TG,TC were decreased(P<0.01).Compare with control group,the expression of LOX-1 and Bax protein on aorta were significantly increased(P<0.01),the Bcl-2 protein and ratio of Bcl-2/Bax was markedly decreased in model group(P<0.01).On the other hand,compare with model group,the expression of LOX-1 and Bax protein were lower,the Bcl-2 protein and ratio of Bcl-2/Bax were prominently higher in the pioglitazone treated group,moreover apoptotic index of aortic intima was significantly lower than the model group.Conclusion:Pioglitazone improves lipid levels in hyperlipidemia rats,which has an effect on expression of apoptosis protein Bax,Bcl-2 in aorta,reducing aortic endothelial cell apoptosis.This maybe have a relation to LOX-1 lowed.",
        "keywords": [
            "Atherosclerosis",
            "Endothelial cells",
            "Apoptosis",
            "Pioglitazone",
            "Lectin-like oxidized low-density lipoprotein receptor-1",
            "Hyperlipidemia"
        ],
        "authors": [
            {
                "name": "Li Rong",
                "org": "School of Clinical Medicine,Southern Medical University Nan Jing,Nanjing ,China;Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "Dong Xiaolei",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "Yuan Aihong",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2012
    },
    "NCtnsgZf": {
        "id": "NCtnsgZf",
        "title": "Ways of logical check in data management with EpiData",
        "abstract": "AIM:To explore the method of logical check in data management in good clinical practice(GCP) with EpiData.METHODS:The two methods of logical check,variable check and recording check were set up through the orders of CHECK and WRITENOTE in EpiData.Validity test on data in database was done.In variable check,the variance was checked as a unit.In recording check,recording in database was done as a unit.RESULTS:The incorrect data would be checked with the above two methods,which can check data in database effectively.CONCLUSION:The function of logical check on data in GCP is a simple,effective and reliable way.",
        "keywords": [
            "EpiData",
            "clinical trial",
            "logical check",
            "data management"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,"
            },
            {
                "name": "LIU Yu-xiu",
                "org": "Department of Medical Affairs,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2008
    },
    "uFcFtDlf": {
        "id": "uFcFtDlf",
        "title": "Expression of Myocardial CTGF in Rats with Pressure Overload and Effect of Tanshinone ⅡA",
        "abstract": "Objective: To observe the changes of connective tissue growth factor( CTGF) expression in rat myocardial tissue with pressure overload,and to explore the protective effects of Tanshinone II A( Tan II A) on myocardial fibrosis.Methods: Twenty-four Sprague-Dawley( SD) rats induced by the abdominal aorta constriction preparation were randomly divided into following apporches( n = 8) : model group( Model group),Tan II A group [TanⅡA group 20 mg( / kg·d) ] and positive captopril group[captopril group 100 mg /( kg d) ]. The matched age SD sham operation( n = 8) was as control. The model of pressure overload-induced myocardial fibrosis was successfully established after 4 weeks of operation. After four weeks of Tan II A treatment,cardiac mass index,left ventricular mass index,histopathological,myocardial hydroxyproline content,myocardial CTGF expression were measured. Results: ①Compared with sham group,cardiac mass index and left ventricular mass index were increased in Model group( P < 0. 01); Compared with Model group,these indexes were decreased in Tan II A group( P < 0. 01). ②Compared with sham group,myocardial hydroxyproline content was increased in Model group( P < 0. 01); Compared with Model group,Tan II A had significantly reduced myocardial hydroxyproline content( P < 0. 01). ③Compared with sham group,CTGF protein content of myocardial tissue was increased in Model group( P < 0. 01); Compared with Model group,Tan II A had significantly reduced the expression of CTGF. Conclusions: Tan II A can inhibit cardiac hypertrophy,attenuate myocardial fibrosis,and this effect may be associated with down-regulation of the expression of fibrogenic cytokines CTGF.",
        "keywords": [
            "Tanshinone ⅡA",
            "connective tissue growth factor",
            "pressure overload",
            "myocardial fibrosis"
        ],
        "authors": [
            {
                "name": "CHANG Wenjing",
                "org": ""
            },
            {
                "name": "ZHAO Lingjie",
                "org": ""
            },
            {
                "name": "ZHAO Zhiming",
                "org": ""
            },
            {
                "name": "SHEN Siyu",
                "org": ""
            },
            {
                "name": "DONG Xiaolei",
                "org": ""
            },
            {
                "name": "CAI Hui",
                "org": ""
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2013
    },
    "wT7uQPvX": {
        "id": "wT7uQPvX",
        "title": "The Shanghai-Salzburg connection:Behind the scenes of the La Boheme co-production",
        "abstract": "Thanks to Alexander Pereira of the Salzburg Festival,a modern co-production of Puccini's La Boheme by Salzburg Festival,Shanghai Grand Theatre and Shanghai Opera House landed in Shanghai from October 18 to 20 after its premiere in Salzburg the past summer.Damiano Michieletto's set design was built by the Shanghai Opera House's stage design studio and weighted 20 tons.Under the baton of the excellent Daniel Oren,Fiorenza Cedolins,Jose Bros,Marco Caria,Guo Sen,Huang Wei,Xue Haoyin,Yang Xiaoyong,Xiong Yufei contributed to three impressive performances with the Shanghai Opera House Orchestra and Chorus.",
        "keywords": [],
        "authors": [
            {
                "name": "周彭灵子",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2012
    },
    "OfOn0ejT": {
        "id": "OfOn0ejT",
        "title": "Urban Planning in Transformation to a International Metropolis: A Probe of Realize Ways to the Rational Growth of Xi′an Urban Space",
        "abstract": "Against the background of economic globalization and regional integration,city religions,with metropolis as the core factor,have become the religional development pattern and space combination form in both global competition and national strategy.As a response to our national strategy intention,this paper formulates the content of Xi'an's building up to a international metropolis in China by reviewing a large amount of related theories and planning methods.Based on the issue of rational city space development,this paper puts forward space planning policies,optimizes valuation system and reforms system procedure to solve the problems faced with Xi'an in its development to an international metropolis by analysising Xi'an's present space development situation and reconstructing its existing space dimension.",
        "keywords": [
            "Xi′an",
            "Rational Growth",
            "Control Approaches",
            "Urban Space"
        ],
        "authors": [
            {
                "name": "YU Kanhua",
                "org": ""
            },
            {
                "name": "ZHANG Pei",
                "org": ""
            },
            {
                "name": "CAI hui",
                "org": ""
            }
        ],
        "venue": "Urban Studies",
        "year": 2011
    },
    "ibrEf7QW": {
        "id": "ibrEf7QW",
        "title": "Effect of the expression of tanshinone ⅡA on myocardial transforming growth factor-β_1 in pressure-overload rats",
        "abstract": "Objective To explore the protective effects of tanshinone(Tan) Ⅱ A on myocardial fibrosis.Methods Models of myocardial fibrosis were established in 60 SD rats induced by the abdominal aorta constriction preparation,and 24 rats of which were survived and randomly divided into sham operation group,model group and Tan Ⅱ A group(20 mg/(kg·d)),with 8 rats in each group.The models were successfully established 4 weeks after operation.The heart mass index,histopathological changes,myocardial hydroxyproline content and myocardial ransforming growth factor(TGF)-β1 expression were measured after four weeks of Tan Ⅱ A treatment.Results The heart mass index,myocardial hydroxyproline content and myocardial TGF-β1 level were obviously higher in model group than those in sham operation group and Tan Ⅱ A group(P<0.01).Conclusion Tan Ⅱ A can inhibit cardiac hypertrophy and attenuate myocardial fibrosis,which may be associated with the downregulation of the expression of TGF-β1.",
        "keywords": [
            "tanshinone ⅡA",
            "Myocardial fibrosis",
            "pressure overload",
            "transforming growth factor-β1",
            "rats"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CHANG Wen-jing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Journal of Chinese Practical Diagnosis and Therapy",
        "year": 2013
    },
    "BZmHdsNI": {
        "id": "BZmHdsNI",
        "title": "Curcumin inhibits osteoclastogenic potential in PBMCs from rheumatoid arthritis patients via the suppression of MAPK/RANK/c-Fos/NFATc1 signaling pathways.",
        "abstract": "The aim of the present study was to determine the effects of curcumin on the osteoclastogenic potential of peripheral blood mononuclear cells (PBMCs) obtained from patients with rheumatoid arthritis (RA), and to investigate the underlying molecular mechanisms. PBMCs from patients with RA (n=12) and healthy controls (n=10) were cultured to assess osteoclastogenic potential. The number of tartrate-resistant acid phosphatase-positive osteoclasts differentiated from PBMCs isolated from patients with RA was significantly increased compared with that of the healthy controls. In addition, the osteoclast number in patients with RA was correlated with the clinical indicators, Sharp score (r=0.810; P=0.001) and lumbar T-score (r=-0.685; P=0.014). Furthermore, the resorption area was increased in the RA group compared with the healthy controls. The mRNA and protein expression levels in PBMC-derived osteoclasts treated with curcumin were measured by reverse transcription-quantitative polymerase chain reaction and western blotting, respectively. Curcumin inhibited the osteoclastogenic potential of PBMCs, potentially by suppressing activation of extracellular signal-regulated kinases 1 and 2, p38 and c-Jun N-terminal kinase, and inhibiting receptor activator of nuclear factor B (RANK), c-Fos and nuclear factor of activated T cells (NFATc1) expression. The results of the present study demonstrated that curcumin may inhibit the osteoclastogenic potential of PBMCs from patients with RA through the suppression of the mitogen-activated protein kinase/RANK/c-Fos/NFATc1 signaling pathways, and that curcumin may be a potential novel therapeutic agent for the treatment of bone deterioration in inflammatory diseases such as RA.",
        "keywords": [
            "rheumatoid arthritis",
            "osteoclasts",
            "peripheral blood mononuclear cells",
            "curcumin",
            "receptor activator of nuclear factor kappa B"
        ],
        "authors": [
            {
                "name": "Wei Shang",
                "org": "Nanjing Univ Chinese Med, Clin Med Coll 1, Nanjing 210023, Jiangsu, Peoples R China"
            },
            {
                "name": "Ling-Jie Zhao",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Xiao-Lei Dong",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Zhi-Ming Zhao",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Jing Li",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Bei-Bei Zhang",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Jinling Hosp, Dept Integrated Tradit Chinese & Western Med, 305 Zhongshan East Rd, Nanjing 210002, Jiangsu, Peoples R China"
            }
        ],
        "venue": "MOLECULAR MEDICINE REPORTS",
        "year": 2016
    },
    "NC555gzH": {
        "id": "NC555gzH",
        "title": "The Excursions of Mr.Broucek was performed on Genève Grand Thé(?)tre",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2008
    },
    "jbcPxv6T": {
        "id": "jbcPxv6T",
        "title": "Abstract LB-444: Transforming growth factor beta polymorphisms and breast cancer survival among Chinese women",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "alicia beeghlyfadiel",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "wei lu",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "jirong long",
                "org": ""
            },
            {
                "name": "y t gao",
                "org": ""
            },
            {
                "name": "ryan delahanty",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2011
    },
    "S8yRjLiS": {
        "id": "S8yRjLiS",
        "title": "Highly efficient gas molecule-tunable few-layer GaSe phototransistors",
        "abstract": "Herein we present a systematic study on the effects of different gas molecules on the photoelectric response of few-layer GaSe phototransistors before and after introducing defects. After introducing defects by thermal annealing, the phototransistors become largely photo-responsive (18.75 A W-1) with high external quantum efficiency (EQE) (similar to 91.53%), high photocurrent on-off ratio, fast photo-response, and good stability in an O-2 rich environment when illuminated by 254 nm ultraviolet light.",
        "keywords": [],
        "authors": [
            {
                "name": "shengxue yang",
                "org": "Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China"
            },
            {
                "name": "qu yue",
                "org": "Natl Univ Def Technol, Coll Sci, Changsha 410073, Hunan, Peoples R China"
            },
            {
                "name": "hui cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "kedi wu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "chengbao jiang",
                "org": "Beihang Univ, Sch Mat Sci & Engn, Beijing 100191, Peoples R China"
            },
            {
                "name": "sefaattin tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "JOURNAL OF MATERIALS CHEMISTRY C",
        "year": 2016
    },
    "jCodoB7O": {
        "id": "jCodoB7O",
        "title": "Influence of curcumin on secretion of VEGF and IL-6 by fibroblast-like synoviocyte in adjuvant arthritis rats",
        "abstract": "Objective It is to observe the effect of curcumin on the secretion of vascular endothelial growth factor(VEGF) and interleukin-6(IL-6) by the fibroblast-like synoviocyte(FLS) in adjuvant arthritis rats.Methods FLS was primary cultured synoviocytes from adjuvant arthritis rats in vitro,and the third generation was added with 0,10,20,40 and 80 μmol/L curcumin to co-culture for 24 h,48 h and 72 h.ELISA method was used to determine the concentration of VEGF and IL-6 in clear supernatant liquid after co-culture.Results After co-cultured for 24 h,VEGF in 40,80 μmol/L curcumin groups and all different levels of curcumin groups after 48 h,72 h was significant different compared with correlated control group.The value of IL-6 of 40 and 80 μmol/L curcumin groups after co-cultured for 24 h,20,40 and 80 μmol/L curcumin groups after 48 h,and all groups after 72 h all obviously decreased,compared to the blank group.ConclusionCurcumin can restraint the secretion of VEGF and IL-6 by FLS in adjuvant arthritis rats,which may be the mechanism of the treatment for rheumatoid arthritis with Curcumin.",
        "keywords": [
            "fibroblast-like synoviocyte",
            "vascular endothelial growth factor",
            "rheumatoid arthritis",
            "interleukin-6"
        ],
        "authors": [
            {
                "name": "Shang Wei",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zhao Lingjie",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zheng Zhaoling",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2010
    },
    "gF4175MP": {
        "id": "gF4175MP",
        "title": "Prediagnosis soy food consumption and lung cancer survival in women.",
        "abstract": "We recently reported an inverse association between soy food intake and lung cancer risk among nonsmoking women. The effect size for aggressive lung cancers was larger than that observed for other types of lung cancer. Therefore, we hypothesized that soy consumption may favorably affect the overall survival of patients with lung cancer.This analysis included 444 women with incident lung cancer identified from the Shanghai Women's Health Study. Prediagnosis soy food intake was assessed at enrollment and reassessed 2 years later. Proportional hazards models were used to evaluate the association between soy food intake and overall survival.Of the 444 patients with lung cancer, 318 died during follow-up. Initial analyses including all patients showed that higher intake of soy food was associated with better overall survival after adjusting for demographic and lifestyle characteristics and other nonclinical factors. Larger effect sizes for the association were found after additional adjustment for tumor stage and treatment in analyses including 301 patients with data available on these clinical factors. Compared with the median intake of soy food, fully adjusted hazard ratios for total mortality associated with the 10th, 30th, 70th, and 90th percentiles of intake were 1.81 (95% CI, 1.26 to 2.59), 1.25 (95% CI, 1.09 to 1.42), 0.88 (95% CI, 0.80 to 0.97), and 0.89 (95% CI, 0.68 to 1.16), respectively. Similar inverse associations were observed for dietary isoflavone intake.This study suggests, to the best of our knowledge for the first time, that, among women with lung cancer, prediagnosis intake of soy food is associated with better overall survival.",
        "keywords": [
            "china",
            "questionnaires",
            "prospective studies",
            "risk factors"
        ],
        "authors": [
            {
                "name": "Gong Yang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Wanqing Wen",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Xianglan Zhang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            }
        ],
        "venue": "Journal of clinical oncology : official journal of the American Society of Clinical Oncology",
        "year": 2013
    },
    "H72XsyuJ": {
        "id": "H72XsyuJ",
        "title": "Change of plasma endothelin in rat with abdominal aortic coarctation",
        "abstract": "Objective It is to observe the change in the level of plasma endothelin in rat with abdominal aortic coarctation by establishing abdominal aortic coarctation rat model.Methods 30 male SD rats were divided into sham-operation group(14 rats) and model group(16 rats).The abdominal aortic of rats were banded with silver clip(inside diameter 0.7 mm) according to method of Doering in model group,and the animals were not banded in sham-operation group.After 8 weeks,the Left ventricular mass index(LVMI) was calculated,and left ventricle pathologic form was observed by collagen staining,and the level of ET was detected by radioimmunoassay.Results In the 8th week,compared whit sham-operation group,the collagen pathologic alterations were obvious in model groups,and the LVMI and the level of ET were increased obviously in model group(P<0.01).Conclusion In the 8th week,the rats myocardium pathologic alterations fit myocardial fibrosis after abdominal aortic coarctation,in which ET play a important role.",
        "keywords": [
            "endothelin",
            "radioimmunoassay",
            "myocardial fibrosis",
            "abdominal aortic coarctation"
        ],
        "authors": [
            {
                "name": "Zhao Lingjie",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Dong Xiaolei",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Guo Junhao",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2009
    },
    "sYDaQ4lv": {
        "id": "sYDaQ4lv",
        "title": "Excitonic Linewidth Approaching the Homogeneous Limit in MoS2 -Based van der Waals Heterostructures",
        "abstract": "The strong light-matter interaction and the valley selective optical selection rules make monolayer (ML) MoS2 an exciting 2D material for fundamental physics and optoelectronics applications. But, so far, optical transition linewidths even at low temperature are typically as large as a few tens of meV and contain homogeneous and inhomogeneous contributions. This prevented in-depth studies, in contrast to the better-characterized ML materials MoSe2 and WSe2. In this work, we show that encapsulation of ML MoS2 in hexagonal boron nitride can efficiently suppress the inhomogeneous contribution to the exciton linewidth, as we measure in photoluminescence and reflectivity a FWHM down to 2 meV at T = 4 K. Narrow optical transition linewidths are also observed in encapsulated WS2, WSe2, and MoSe2 MLs. This indicates that surface protection and substrate flatness are key ingredients for obtaining stable, high-quality samples. Among the new possibilities offered by the well-defined optical transitions, we measure the homogeneous broadening induced by the interaction with phonons in temperature-dependent experiments. We uncover new information on spin and valley physics and present the rotation of valley coherence in applied magnetic fields perpendicular to the ML.",
        "keywords": "",
        "authors": [
            {
                "name": "F. Cadiz",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "E. Courtade",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Cédric Robert",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Gang Wang",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Yuxia Shen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Takashi Taniguchi",
                "org": "Natl Inst Mat Sci, Tsukuba, Ibaraki 3050044, Japan"
            },
            {
                "name": "Kenji Watanabe",
                "org": "Natl Inst Mat Sci, Tsukuba, Ibaraki 3050044, Japan"
            },
            {
                "name": "H. Carrère",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "D. Lagarde",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "M. Manca",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "T. Amand",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "P. Renucci",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "X. Marie",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "B. Urbaszek",
                "org": "Univ Toulouse, INSA, CNRS, UPS,LPCNO, 135 Ave Rangueil, F-31077 Toulouse, France"
            }
        ],
        "venue": "PHYSICAL REVIEW X",
        "year": 2017
    },
    "Kt5lRUNX": {
        "id": "Kt5lRUNX",
        "title": "Application of MBR/DTRO/Zeolite Biological Aerated Filter in Treatment of Landfill Leachate",
        "abstract": "The design capacity of landfill leachate treatment extension project of Qingdao Xiaojianxi municipal solid waste comprehensive treatment plant is 900 m3/d,and MBR/DTRO/zeolite biological aerated filter are used.The project design is introduced,and the design parameters,technological processes and design characteristics of MBR system,DTRO system and zeolite biological aerated filter system are emphatically expounded to provide reference for application of this process in landfill leachate treatment.",
        "keywords": [
            "landfill leachate",
            "DTRO",
            "MBR",
            "zeolite biological aerated filter"
        ],
        "authors": [
            {
                "name": "CHEN Gang",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            },
            {
                "name": "XIONG Xiang-yang",
                "org": "China Urban Construction Design and Research Institute,Beijing ,China"
            },
            {
                "name": "PENG Zhong",
                "org": "Qingdao City Investment Environment and Energy Co.Ltd.,Qingdao ,China"
            }
        ],
        "venue": "China Water & Wastewater",
        "year": 2011
    },
    "L5XTzfVq": {
        "id": "L5XTzfVq",
        "title": "Effect of metoprolol on changes of plasma NE & Ang Ⅱ in rats with ISO-induced congestive heart failure.",
        "abstract": "Objective To explore the effect of metoprolol on plasma Renin and Angiotensin Ⅱ in fats with heat failure.Methods 60 Male Sprague-Dawley rats were randomly allocated to the ISO-induced chronic heart falilure group(n=50) receiving two subcutaneous injections of 170mg ISO per-kilogram of body and the healthy normal group(NOR group,n= 10) receiving two subcutaneous injections of 0.25ml normal saline.At 6th week,the left ventricular ejection fraction(LVEF) was measured by echocardiogram,the remaining rats,with an left ventricular ejection fraction≤45%,were randomly divided into two groups: control group(n=10),metoprolol group 8 mg/(kg·d)(n=10).the drugs were given i.g.At 18th week,then the hemody namic parameters were detected,including heart rate,left ventricular end diastolic pressure,LV systolic pressure;LVWI was measured after LV morphopathological examination,the Renin and Angiotensin Ⅱ in plasma were detected by ELISA and radio-immunity method,the mass ratio of heart ventricle and left ventricle to body was measured. Results ①Compared with the NOR group,the HR、LVEDP,LVWI and the Renin and Angiotensin Ⅱ in plasma were significantly increased(P<0.01).But LVSP and ±dp/dtmax were significantly decreased in the CON group.②Compared with the CON group,the HR、LVEDP、LVWI and the Renin and AngiotensinⅡin plasma were decreased distinctly.the LVSP and±dp/dtmax were increased distinctly(P<0.01) in the MET group.Conclusion Metoprolol can inhibit the Renin and AngiotensinⅡin plasma,inprove heart function and reverse ventricular remodeling with congestive heart failure.",
        "keywords": [
            "CHF",
            "myocardial remodeling",
            "isoproterenol",
            "SD rats",
            "metoprolol",
            "RAS"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al.Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "GUO Han",
                "org": ",et al.Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "LU Le",
                "org": ",et al.Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Sichuan Medical Journal",
        "year": 2010
    },
    "rVva9t23": {
        "id": "rVva9t23",
        "title": "Analysis on operation conditions of UPFC in Nanjing western power system in 2016",
        "abstract": "Unified Power Flow Controller (UPFC) project in Nanjing western power system (NWPS) has been put into operation since December 2015. As the first project based on modular multi-level converter (MMC) technology in the world, it represents the highest level in the field of flexible alternative current transmission system (FACTS). Therefore, the real operation conditions of this project are important for the research and extended utilization of UPFC. In this paper, necessity and feasibility for the application of UPFC in NWPS is firstly introduced. Then, preset system-level control strategy of UPFC is discussed. Afterwards, based on load characteristics of NWPS in 2016, real system control strategy of UPFC and its balance for power flow from north and south-transferred channels is deeply analyzed. The analysis shows that the application of UPFC can effectively solve the problems of power flow misdistribution, insufficient power supply capacity and huge investment for construction of new transmission channels in NWPS. This project plays an exemplary role to promote FACTS technology for power grids with high city urbanization levels to improve power supply capability.",
        "keywords": "",
        "authors": [
            {
                "name": "Tianran Yin",
                "org": "Department of Electrical Engineering, Southeast University, Nanjing, P.R. China"
            },
            {
                "name": "Xi Wu",
                "org": "Department of Electrical Engineering, Southeast University, Nanjing, P.R. China"
            },
            {
                "name": "Siqi Bu",
                "org": "Department of Electrical Engineering, The Hongkong Polytechnic University, Hongkong"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute, P.R. China"
            },
            {
                "name": "Wanchun Qi",
                "org": "State Grid Jiangsu Economic Research Institute, P.R. China"
            },
            {
                "name": "Junhui Huang",
                "org": "State Grid Jiangsu Economic Research Institute, P.R. China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "State Grid Jiangsu Economic Research Institute, P.R. China"
            }
        ],
        "venue": "electrical power and energy conference",
        "year": 2017
    },
    "dcsw3YRj": {
        "id": "dcsw3YRj",
        "title": "Retaining the Root:The Protection Planning and Practice of Xiyangshi Street in Xi’an City",
        "abstract": "Nowadays the protection and renewal of historical block has been an important constituent in Chinese urban development. On the basis of the protec-tion practice of Xiyangshi Street block,the article profoundly studies the cultural contexts,street spaces and buildings,integrate each part in the block system. Furthermore,a feasible method combin-ing urban landscape with traditional con-text has been discussed at the end.",
        "keywords": [
            "culture inheritance",
            "historical block",
            "city renewal",
            "develop-ment"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ""
            },
            {
                "name": "YU Kan-hua",
                "org": ""
            },
            {
                "name": "JING Xiao-peng",
                "org": ""
            }
        ],
        "venue": "Modern Urban Research",
        "year": 2007
    },
    "RjOJwcYb": {
        "id": "RjOJwcYb",
        "title": "Disscussion on Clinical Effects of Duhuo-Jisheng Tang on Rheumatoid Arthritis",
        "abstract": "Objective:To observe the effects of Duhuo-Jisheng Tang on the treatment of Rheumatoid Arthritis.Methods:Atotal of 70 patients with rheumatoid arthritis were randomly divided into two group,the 35 patients in the control group were give tripterygium wilfordii,and the 35 patients in the treating group were additionally given Duhuo-Jisheng Tang.The course of treatment lasted for 1 months.Results:After the treatment,there were obvious improvements in joint ache,swelling,tendmess,jointmovable degree moring rigidity and ESR,CRP.The curative effect rate in the treatment group was higher than that in the control group(P<0.05).Conclusion:Lt is indicated that Duhuo-Jisheng Tang has a significant therapeutic effect on rheumatoid arthritic.",
        "keywords": [
            "Rheumatoid arthritic:Treatment with TCM:Duhuo-Jisheng Tang"
        ],
        "authors": [
            {
                "name": "WU Li-qun",
                "org": "PLA No.85 Hospital,Shanghai 20052,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YU De-yong",
                "org": "Nanjing General Hospital of PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Hua",
                "org": "Nanjing General Hospital of PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Liaoning Journal of Traditional Chinese Medicine",
        "year": 2010
    },
    "ajuGbtPi": {
        "id": "ajuGbtPi",
        "title": "Study on Regressing Myocardial Fibrosis in Rat with Pressure Overload by Bu Shen Prescription",
        "abstract": "Objective:To observe the effects of Bu Shen Prescription on regressing myocardial fibrosis in rat with pressure overload. Methods:The model of left ventricular remodeling in rat with pressure overload by abdominal aortic constriction was used. 60 SD male rats were randomly divided into five groups:sham operation group,model group,captopril group,Bu Shen Prescription high dosage group and low dosage group. After treatment 4 weeks,it was observed that the changes of left ventricular myocardium collagen pathological coloring,left ventricular interstitial cardiac tissue ultramicrostructure,left ventricular cardiac tissue collagen type Ⅰimmunohistochemistry coloring and collagen type Ⅲ immunohistochemistry coloring. Results:The average optic density of left ventricular cardiac tissue type Ⅰcollagen and type Ⅲ collagen of model group were increased obviously than that of sham operation group (P<0.01). The average optic density of left ventricular cardiac tissue type Ⅰcollagen and type Ⅲ collagen of captopril group,Bu Shen Prescription high dosage group and low dosage group were lower than those of model group significantly(P<0.01). The changes of left ventricular myocardium collagen pathological coloring and left ventricular interstitial cardiac tissue ultramicrostructure were consistent with those of typeⅠ collagen and type Ⅲ collagen. Conclusion:Bu Shen Fu Prescription and captopril had similar effects on regressing myocardial fibrosis.",
        "keywords": [
            "collagen type Ⅰand Ⅲ",
            "Bu Shen Prescription",
            "pressure overload",
            "myocardial fibrosis"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2010
    },
    "SDtMwpuW": {
        "id": "SDtMwpuW",
        "title": "Study on Co-immobilized Algal-bacterial to Remove Organics of Municipal Wastewater under Different Illumination",
        "abstract": "Co-immobilized algal-bacterial removing organics were studied in different illumination time including lightened all day,half day and dark always and under different light source:fluorescent lamp and fluorescent lamp by continuous experiments,The results show illumination time has little effect on removing organics and the effect of co-immobilized algal-bacterial removing organics under diode lamp is better than fluorescent lamp on fitting and energy consumption.",
        "keywords": [
            "removing organics",
            "immobilization",
            "illumination"
        ],
        "authors": [
            {
                "name": "Pan Hui",
                "org": "The Department of Civil Engineering,Hebei Vocational & Technical College of Building Materials,Qinhuangdao ,China"
            },
            {
                "name": "Cai Hui",
                "org": "Urban Construction Design & Research Institute,Beijing ,China"
            }
        ],
        "venue": "Environmental Science and Management",
        "year": 2009
    },
    "8pPza9KO": {
        "id": "8pPza9KO",
        "title": "The Zodiac & Opera",
        "abstract": "The Zodiac and opera seem totally unrelated to each other.Is there any relation.ship be- tween them?Can each of the Zodiac signs be matched to an opera according to its particular character?Let' s listen to what three ladies have to say...",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2007
    },
    "nTvN7Fqu": {
        "id": "nTvN7Fqu",
        "title": "The Effects of Rho Kinase Inhibitor on Cardiac Fibrosis in Pressure-overload Rats",
        "abstract": "Objective: To investigate the effects of fasudil, a Rho kinase inhibitor, on cardiac fibrosis in pressure-overload rats. Method: The SD rats were prepared with abdominal aorta constriction and fed under standard condition. The abdominal aortas were clipped for 4 weeks. These rats were divided into 4 groups randomly: sham group, model group, fasudil high-dose group (FH, 30mgKgd) and fasudil low-dose group (FL, 10mgKgd). At 8 weeks after surgery, the left ventricleweight index (LVWI) were calculated, and the content of cardiac hydroxyproline (HYP) was measured using alkaline hydrolysis. Myocardial histopathology and interstitial fibrosis were detected with HE and Masson staining. Transforming growth factor β1 (TGF-β1) and connective tissue growth factor (CTGF) were analyzed with immunohistochemistry. Results: Comparing with sham group, the LVWI and HYP content were significantly elevated in model group (P<0.01). Much more collagen deposited in myocardial interstitium. Rho kinase activity was significantly elevated, associated with increased TGF-β1 and CTGF(P<0.01). Comparing with the model group, fasudil reduced the LVWI and HYP content, and reduced interstitial collagen deposition. Rho kinase activity was significantly decreased associated with much lower expression of TGF-β1 and CTGF (P<0.05). Conclusion: Rho kinase plays an important role in abdominal aortic constriction induced myocardial fibrosis. Decreased TGF-β1 and CTGF partly contribute to the protective effect of fasudil on heart against pressure-overload.",
        "keywords": [
            "Connective tissue growth factor",
            "Transforming growth factor β1",
            "Rho kinase",
            "Cardiac fibrosis",
            "Fasudil"
        ],
        "authors": [
            {
                "name": "Zhang Peiyong",
                "org": "Nanjing School of Clinical Medicine, Southern Medical University, Nanjing , China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command, Nanjing , China"
            },
            {
                "name": "Zhao Lingjie",
                "org": "Nanjing General Hospital of Nanjing Military Command, Nanjing , China"
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2013
    },
    "q6ccnuoD": {
        "id": "q6ccnuoD",
        "title": "Abstract 2272: A prospective study of urinary prostaglandin E2 metabolite,Helicobacter pyloriantibodies, and gastric cancer risk",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Tianyi Wang",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Angelika Michel",
                "org": ""
            },
            {
                "name": "Michael Pawlita",
                "org": ""
            },
            {
                "name": "Ginger L. Milne",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Nathaniel Rothman",
                "org": ""
            },
            {
                "name": "Qing Lan",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Meira Epplein",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2017
    },
    "uoLvD5jt": {
        "id": "uoLvD5jt",
        "title": "Postdiagnosis cruciferous vegetable consumption and breast cancer outcomes: a report from the After Breast Cancer Pooling Project.",
        "abstract": "Cruciferous vegetables are a major source of glucosinolate-derived bioactive compounds such as isothiocyanates, which have been shown in animal and in vitro studies to inhibit cancer growth and progression. Few studies have investigated cruciferous vegetable intake after diagnosis and breast cancer outcomes. Using data from the After Breast Cancer Pooling Project, which includes prospective data from U. S. and Chinese breast cancer survivors, we evaluated the association of cruciferous vegetables with breast cancer outcomes. Analyses included 11,390 women diagnosed with stage I-III invasive breast cancer (1990-2006) from four cohorts. Cruciferous vegetable intake (g/day) was assessed using food frequency questionnaires (mean of 22 months postdiagnosis). Study heterogeneity was evaluated by the Q statistic; hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using delayed-entry Cox regression models stratified by study. After a median follow-up of 9.0 years, 1,725 deaths and 1,421 recurrences were documented. In pooled analyses using study-specific quartiles, cruciferous vegetable intake was not associated with breast cancer outcomes, adjusting for known clinical prognostic factors and selected lifestyle factors. HRs (95% CIs) by increasing quartiles (reference = lowest quartile) were 1.08 (0.93-1.25), 1.01 (0.87-1.18), and 1.10 (0.95-1.28) for recurrence (P-trend = 0.34) and 1.01 (0.88-1.15), 0.97 (0.84-1.11), and 0.99 (0.86-1.13) for total mortality (P-trend = 0.84). No associations were observed for subgroups defined by estrogen receptor status, stage, or tamoxifen therapy. Cruciferous vegetable intake at approximately two years after diagnosis was not associated with recurrence or mortality. Our results do not support an association between postdiagnosis cruciferous vegetable intake and breast cancer outcomes. (C) 2013 AACR.",
        "keywords": [],
        "authors": [
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Bette J Caan",
                "org": "Kaiser Permanente No Calif, Div Res, Oakland, CA USA"
            },
            {
                "name": "Wendy Y Chen",
                "org": "Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Div Network Med,Dept Med, Boston, MA 02115 USA"
            },
            {
                "name": "Marilyn L Kwan",
                "org": "Kaiser Permanente No Calif, Div Res, Oakland, CA USA"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Ctr Dis Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Elizabeth M Poole",
                "org": "Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Div Network Med,Dept Med, Boston, MA 02115 USA"
            },
            {
                "name": "Shirley W Flatt",
                "org": "Univ Calif San Diego, Moores UCSD Canc Ctr, Canc Prevent & Control Program, San Diego, CA 92103 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "John P Pierce",
                "org": "Univ Calif San Diego, Moores UCSD Canc Ctr, Canc Prevent & Control Program, San Diego, CA 92103 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2013
    },
    "eF6Fvp9J": {
        "id": "eF6Fvp9J",
        "title": "Influnnce of Bu Shen Prescription on local angiotensin Ⅱin myocardial tissues of rats with pressure overload",
        "abstract": "Objective:To observe the influence of Bu Shen Prescription on the level of local angiotensin Ⅱ(AngⅡ)in the left ventricular myocardial tissue of rats with pressure overload,and to study the possible mechanism of regressing the left ventricular remodeling.Methods:Sixty SD male rats were randomly divided into five groups:shan operatien group,untreated group,captopril group,Bushen prescription high dosage group and the low dosage group,12 rats in each group.Left venticular mass index(LVMI)was measured,and pathological morphology was observed.Radioimmunoassay was used to detect the local AngⅡlevel of the left ventricular myocardial tissue.Results:The AngⅡ level of the left ventricular myocardial tissue in model group was higher than that of sham operation group(P<0.01).In captopril group,Bu Shen Prescription high dosage group and low dosage group,the AngⅡ level was lower than that in model group(P<0.01).The left ventricular myocardial pathological morphology was similar except untreated group.Conclusions:Bu Shen Prescription and captopril have similar effects in regressing the left ventricular remodeling in rats with pressure overload,which may be concerned with the decrease of local AngⅡ level of the left ventricular myocardial tissue.",
        "keywords": [
            "left ventricular remodeling",
            "angiotensin Ⅱ",
            "Bu Shen Prescription",
            "pressure overload",
            "rats"
        ],
        "authors": [
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Bengbu Medical College",
        "year": 2010
    },
    "1PSSeCOc": {
        "id": "1PSSeCOc",
        "title": "MONOCYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "darin allen",
                "org": ""
            },
            {
                "name": "michael k ameriks",
                "org": ""
            },
            {
                "name": "frank u axe",
                "org": ""
            },
            {
                "name": "matthew t burdett",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "ingrid c choong",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "willard lew",
                "org": ""
            },
            {
                "name": "steven p meduna",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "P5sHPV6n": {
        "id": "P5sHPV6n",
        "title": "Metoprolol reduces nitric oxide in the myocardium of rats with isoproterend-induced congestive heart failure",
        "abstract": "Objective Several studies on the relationship between nitric oxide(NO) and ventricular remodeling have been reported recently.The authors aimed to investigate the mechanism of metoprolol acting on ventricular remodeling in rats with congestive heart failure(CHF) by observing the effect of metoprolol on NO in the myocardium of isoproterend(ISO)-induced CHF rat models.Methods Eighty male SD rats were randomly allocated to an ISO-induced CHF group(ISO,n=70) and a normal control group(NOR,n=10),the former receiving 2 subcutaneous injections of ISO at 170 mg/kg,and the latter 2 subcutaneous injections of 0.25 ml normal saline.Six weeks later,the left ventricular ejection fraction(LVEF) was measured by echocardiography,the rats with an LVEF≤45% were randomly divided into a compensation group(COMP) and a heart failure group,and the latter again randomly assigned to a decompensation heart failure group(DECOMP) and a metoprolol group(MET).At 18 weeks,heart function parameters,including LEVF,FS,LVEDD,LVESD and LVWI,were obtained following LV morphopathological examination,and NO was detected by the nitrate reductase method.Results Compared with the NOR group,heart function was markedly decreased,but LVWI,pathological scores and NO in the myocardium significantly increased(P<0.05) in the DECOMP and COMP groups.While the metoprolol group showed a distinct increase in heart function and a significant decrease in LVWI,pathological scores and NO(P<0.05) in comparison with the DECOMP and COMP groups.Conclusion Metoprolol can down-regulate NO in the myocardium and improve ventricular remodeling and heart function in the rat models of ISO-induced CHF.",
        "keywords": [
            "Rat",
            "Nitric oxide",
            "Congestive heart failure",
            "Metoprolol"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Jia-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "JIAO Dong-dong",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LU Le",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Han",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2010
    },
    "SBs0YqUX": {
        "id": "SBs0YqUX",
        "title": "Advances in drugs on preventing joint destruction of rheumatoid arthritis",
        "abstract": "A growing body of evidence has shown that patients with Anti-Cyclic Citrullinated Peptide and Anti-Sa antibodies positive had significantly higher incidence of joints destruction than that not.During the last decades,the drugs preventing joint destruction have been well established,containing anti-tumor necrosis factor antagonist, interleukin receptor antagonist, matrix metalloproteinase inhibitor, vascular endothelial growth factor,methotrexate,glucocorticoids and Chinese Medicine.However,the biological agents are too expensive to widespread application and long-term clinical observation,while the Chinese Medicine for its distinct advantages in preventing joint destruction is becoming a focal point for rheumatologist study.",
        "keywords": [
            "Rheumatoid arthritis",
            "Joint damage",
            "Drugs"
        ],
        "authors": [
            {
                "name": "ZHANG Yongwen",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "SHEN Siyu",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Osteoporosis",
        "year": 2010
    },
    "BKHZYwpI": {
        "id": "BKHZYwpI",
        "title": "Prevalence and determinants of metabolic syndrome according to three definitions in middle-aged Chinese men.",
        "abstract": "Background: The prevalence of metabolic syndrome has varied markedly between different studies because of the lack of internationally agreed-upon criteria to define the condition. We estimated the prevalence and lifestyle risk factors of metabolic syndrome according to three definitions of metabolic syndrome in urban Chinese men participating in the Shanghai Men's Health Study (SMHS). Methods: In this cross-sectional study, 3988 middle-aged, urban Chinese men 40-74 years of age who were free of type 2 diabetes at baseline provided fasting blood samples, anthropometric measurements, and information on lifestyle factors and disease history. Results: The three definitions of metabolic syndrome used in this report are from the International Diabetes Federation (IDF), the U.S. Third Report of the National Cholesterol Education Program, Adult Treatment Panel (ATP III), and a modified version of the ATP III criteria for Asian populations (ATP III-modified criteria). The prevalence of metabolic syndrome was 18.63%,18.36%, and 29.34% according to IDF, ATP 111, and ATP III-modified criteria, respectively. Agreement between the IDF and ATP III criteria was moderate (kappa = 0.43), whereas agreement between ATP III-modified and the IDF and ATP III criteria was good (kappa = 0.71 and 0.70, respectively). Physical activity was associated with a lower prevalence of metabolic syndrome, whereas drinking more than three drinks per day was associated with a higher risk of metabolic syndrome, regardless of the criteria employed. The association between smoking and the prevalence of metabolic syndrome in this population failed to reach significance. Conclusions: Results from this representative sample of middle-aged, urban Chinese men show that metabolic syndrome is highly prevalent in this population. Our data support the hypothesis that physical activity decreases the risk of developing metabolic syndrome and that high alcohol consumption increases risk.",
        "keywords": [
            "risk assessment",
            "cross sectional studies",
            "risk factors",
            "prevalence",
            "waist hip ratio",
            "china",
            "odds ratio"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Sergio Fazio",
                "org": "Vanderbilt Univ, Div Cardiovasc, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "MacRae F Linton",
                "org": "Vanderbilt Univ, Div Cardiovasc, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Tom Elasy",
                "org": "Vanderbilt Univ, Ctr Diabet Res & Training, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Med Ctr, Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "METABOLIC SYNDROME AND RELATED DISORDERS",
        "year": 2009
    },
    "vPuM3aXg": {
        "id": "vPuM3aXg",
        "title": "Association of hypertension and obesity with renal cell carcinoma risk: a report from the Shanghai Men’s and Women’s Health Studies",
        "abstract": "Consistently reported associations between hypertension and obesity and renal cell carcinoma (RCC) risk have largely come from studies in Western populations. These associations were examined in a case–control study nested in the Shanghai Women’s Health Study (SWHS, 1996–2000) and Shanghai Men’s Health Study (SMHS, 2001–2006).",
        "keywords": [
            "Body mass index",
            " Carcinoma",
            " Renal cell",
            " Case–control",
            " Hypertension",
            " Obesity"
        ],
        "authors": [
            {
                "name": "tian shen",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "yongbing xiang",
                "org": "Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "honglan li",
                "org": "Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "y gao",
                "org": "Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university school of medicine"
            },
            {
                "name": "loren lipworth",
                "org": "vanderbilt university school of medicine"
            }
        ],
        "venue": "Cancer Causes & Control",
        "year": 2015
    },
    "GaFBlHuR": {
        "id": "GaFBlHuR",
        "title": "Plant and Animal Protein Intakes and Risk of Incident Kidney Stones: Results from the Shanghai Men's and Women's Health Studies.",
        "abstract": "Purpose: High animal protein intake is a risk factor for nephrolithiasis. Whether plant based sources of protein are associated with kidney stone risk is not well studied. We examined the association of animal and plant protein intake with the risk of incident kidney stones in Shanghai, China. Materials and Methods: Dietary intakes were obtained from a validated food frequency questionnaire at baseline. Self-reported stone events were ascertained at baseline and at followup visits. Multivariable Cox regression models were used to evaluate the associations of protein intake with the incident stone risk. Results: During 319,211 and 696,950 person-years of followup 1,451 men and 1,202 women, respectively, reported incident stones. The average +/- SD intake of animal and plant protein standardized to 2,000 kcal was 31.3 +/- 13.7 and 48.4 +/- 7.2 gm per day in women, and 30.8 +/- 13.3 and 51.3 +/- 7.6 gm per day, respectively, in men. On multivariable analysis participants in the highest quintiles of animal and nondairy animal protein intake showed an increased risk of incident stones compared to those in the lowest quintiles (HR 1.16, 95% CI 1.01-1.32, p=0.03 vs HR 1.14, 95% CI 1.01-1.30, p=0.04). Compared to the lowest quintile the highest intake quintiles of the animal-to-plant protein ratios and the nondairy animal-to-plant protein ratios were positively associated with stone risk (HR 1.17, 95% CI 1.03-1.33, p=0.02 and HR 1.20, 95% CI 1.06-1.36, p=0.005, respectively). No association was observed with plant protein intake (p(trend)=0.14). Conclusions: In this population with a relatively low animal protein intake and a high plant protein intake, a greater animal protein intake was associated with a kidney stone risk. Increasing the proportion of plant protein relative to animal protein appeared protective against the risk.",
        "keywords": [
            "kidney calculi",
            "dietary proteins",
            "plant proteins",
            " dietary",
            "risk factors",
            "China"
        ],
        "authors": [
            {
                "name": "Xiang Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Med Ctr, Nashville, TN USA"
            },
            {
                "name": "Joshua K Calvert",
                "org": "Vanderbilt Univ, Med Ctr, Dept Urol, Nashville, TN USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Med Ctr, Nashville, TN USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Univ Sch Med, Renji Hosp, Shanghai Canc Inst, State Key Lab Oncogene & Related Genes, Shanghai, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Univ Sch Med, Renji Hosp, Shanghai Canc Inst, State Key Lab Oncogene & Related Genes, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Med Ctr, Nashville, TN USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Med Ctr, Nashville, TN USA"
            },
            {
                "name": "Ryan S Hsi",
                "org": "Vanderbilt Univ, Med Ctr, Dept Urol, Nashville, TN USA"
            }
        ],
        "venue": "JOURNAL OF UROLOGY",
        "year": 2019
    },
    "v7IZbsvo": {
        "id": "v7IZbsvo",
        "title": "Replication study for reported SNP associations with breast cancer survival.",
        "abstract": "Nine previously reported associations between single nucleotide polymorphisms (SNPs) and breast cancer outcomes from the Shanghai Breast Cancer Study (Stage 1) were further evaluated in relation to disease-free survival (DFS) and overall survival (OS) among 5,192 additional breast cancer patients (Stage 2).Hazard ratios (HR) and 95% confidence intervals (CI) were calculated by proportional hazards regression in models adjusted for age, disease stage, estrogen and progesterone receptor status, and treatment regimens.Two SNPs had generally consistent results and significant associations with OS in combined analyses. Compared to women with MMP7 rs11225297 AA genotypes, OS was moderately better for women with AT genotypes (HR: 0.8, 95% CI: 0.7-1.0) and much better for women with TT genotypes (HR: 0.4, 95% CI: 0.2-0.8). Compared to women with MMP8 rs11225395 CC genotypes, OS was slightly better for women with CT genotypes (HR: 0.9, 95% CI: 0.7-1.1) and moderately better for women with TT genotypes (HR: 0.6, 95% CI: 0.4-0.9). Joint analysis showed significant dose-response relationships with increasing numbers of rare alleles for both OS (p < 0.001) and DFS (p = 0.001).A functional variant in MMP8 and a SNP in high linkage disequilibrium with a functional variant in MMP7 were significantly associated with breast cancer survival in a large two-stage survival study among Chinese women. This supports the hypothesis that SNPs in matrix metalloproteinase genes may influence breast cancer prognosis; additional research on these and other SNPs in genes important in metastasis, angiogenesis, and the regulation of the tumor microenvironment is warranted.",
        "keywords": [
            "Breast cancer",
            "Survival",
            "Genetic variants",
            "Replication",
            "Matrix metalloproteinases"
        ],
        "authors": [
            {
                "name": "Alicia Beeghly-Fadiel",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Zhi Chen",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "Journal of cancer research and clinical oncology",
        "year": 2012
    },
    "tdBOcKUI": {
        "id": "tdBOcKUI",
        "title": "Nitrite Modification of Extracellular Matrix Alters CD46 Expression and VEGF Release in Human Retinal Pigment EpitheliumNitrite-Modified ECM Alters CD46 and VEGF In Vitro",
        "abstract": "",
        "keywords": [
            "extracellular matrix",
            "vascular endothelial growth factor a"
        ],
        "authors": [
            {
                "name": "mark a fields",
                "org": "medical university of south carolina"
            },
            {
                "name": "hui cai",
                "org": "columbia university college of physicians and surgeons"
            },
            {
                "name": "hannah e bowrey",
                "org": "medical university of south carolina"
            },
            {
                "name": "ernesto f moreira",
                "org": "medical university of south carolina"
            },
            {
                "name": "monika gooz",
                "org": "medical university of south carolina"
            },
            {
                "name": "kannan kunchithapautham",
                "org": "medical university of south carolina"
            },
            {
                "name": "jie gong",
                "org": "medical university of south carolina"
            },
            {
                "name": "e vought",
                "org": "medical university of south carolina"
            },
            {
                "name": "lucian v del priore",
                "org": "medical university of south carolina"
            }
        ],
        "venue": "Investigative Ophthalmology & Visual Science",
        "year": 2015
    },
    "Bf6GyU0x": {
        "id": "Bf6GyU0x",
        "title": "Peroxisome proliferator-activated receptor delta (PPARD) genetic variation and type 2 diabetes in middle-aged Chinese women.",
        "abstract": "Animal studies have shown that the peroxime proliferator-activated receptor delta (PPARD) gene regulates glucose metabolism and insulin sensitivity. Genetic variation in the PPARD gene might affect physical endurance and has been associated with obesity. We investigated the independent and modifying effect of variants in the PPARD gene with exercise participation and body mass index (BMI) on type 2 diabetes (T2D), using data from a genome-wide association study (GWAS) of middle-aged women living in Shanghai, China, with 1019 T2D cases and 1709 controls. The genotyping was performed using the Affymetrix Genome-Wide Human SNP Array 6.0 platform. Imputation was used to determine missing genotypes. Participation in exercise was assessed by a questionnaire. Anthropometric variables were measured by trained interviewers. The association between polymorphisms and T2D was assessed by logistic regression analyses. The combined effects of polymorphisms in the PPARD gene with exercise participation and BMI on T2D risk was assessed by conducting stratified analysis with exercise participation and BMI categories. No significant associations between PPARD and T2D were found in either genotyped or imputed SNPs and no effect modification between exercise participation and PPARD genetic variation was found, suggesting that PPARD is not a risk factor for T2D in this population.",
        "keywords": [
            "Type 2 Diabetes",
            "PPARD"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Scott Williams",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Yutang Gao",
                "org": "Vanderbilt Univ, Ctr Human Genet Res, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Vanderbilt Univ, Ctr Human Genet Res, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA"
            },
            {
                "name": "Tom Elasy",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Todd Edwards",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Vanderbilt Univ, Ctr Human Genet Res, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Med Ctr, Nashville, TN 37203 USA"
            }
        ],
        "venue": "ANNALS OF HUMAN GENETICS",
        "year": 2011
    },
    "sXxGAI4G": {
        "id": "sXxGAI4G",
        "title": "Transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells reduces myelosyringosis after spinal cord injury",
        "abstract": "BACKGROUND: Previous studies have demonstrated that transplantation of controlled release glial cell line-derived neurotrophic factor (GDNF) and bone marrow mesenchymal stem cells-derived neuron-like cells (BMSCs) can effectively promote the motor function recovery of rhesus monkeys with spinal cord injury. OBJECTIVE: To validate whether GDNF+BMSCs transplantation exhibits better protective effects on spinal cord tissue of rhesus monkeys with spinal cord injury than BMSCs transplantation. METHODS: Rhesus monkey models of acute severe spinal cord injury were divided into three groups and received GDNF+BMSCs transplantation (GDNF+BMSCs group) or BMSCs transplantation (BMSCs group) or PBS administration (control group). Spinal cord tissue was embedded with paraffin and stained with hematoxylin-eosin. Myelosyringosis was estimated by image analysis system. RESULTS: In the control group, spinal cord structure was greatly destructed, and myelosyringosis occupied larger area. In the BMSCs group, spinal cord structure was well preserved, and small cavities, occasionally large cavities, were observed. In the GDNF+BMSCs group, spinal cord structure was best preserved and only small cavities were observed. There was significant difference in spinal cord structure destruction between groups (P < 0.01). These findings suggest that compared with simple BMSCs transplantation, transplantation of controlled released GDNF+BMSCs shows better protective effects on spinal tissue structure after spinal cord injury, which may be one of mechanisms by which myelosyringosis is reduced to a greater extent.",
        "keywords": [
            "rhesus monkey",
            "neurotrophic factor",
            "stem cells",
            "stem cell transplantation",
            "bone marrow-derived mesenchymal stem cells",
            "spinal cord injury",
            "other grants-supported paper",
            "myelosyringosis",
            "stem cell photographs-containing paper"
        ],
        "authors": [
            {
                "name": "Liu Xiao-gang",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            },
            {
                "name": "Deng Yu-bin",
                "org": " Department of Pathology and Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou , Guangdong Province, China"
            },
            {
                "name": "Cai Hui",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            },
            {
                "name": "Wang Li-ning",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            },
            {
                "name": "Ma Yu-lin",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            },
            {
                "name": "Zhang Xin-peng",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            },
            {
                "name": "Wei Ke-xin",
                "org": " Department of Pathology, Chui Yang-liu Hospital of Beijing, Beijing , China"
            }
        ],
        "venue": "Chinese Journal of Tissue Engineering Research",
        "year": 2013
    },
    "PQR9Ykjl": {
        "id": "PQR9Ykjl",
        "title": "Effect of Total Flavonoids of Epimedium on Plasma Levels of TNF-α in Rats with Congestive Heart Failure",
        "abstract": "Objective To explore the effects of total flavonoids of epimedium(TFE) on plasma levels of tumour necrosis factor-α(TNF-α) in rats with congestive heart failure(CHF).Methods Eighty male SD rats were randomly allocated to normal control group(n=10) and model control group(n=70).The CHF model was induced by subcutaneous injection of isoproterenol 170 mg/kg,for a total of two times with an interval of 24 hours.At the sixth week,left ventricular ejection fraction(LVEF) was measured by echocardiogram,and the CHF model was defined as LVEF≤45%.Then,the model rats were randomly divided into three groups: CHF control group(n=10),metoprolol treated group,and TFE treated group.At the 18th week,hemodynamic parameters were measured,including heart rate(HR),left ventricular end diastolic pressure(LVEDP),and left ventricular systolic pressure(LVSP),maximal rate of left ventricular pressure of development(+dp/dtmax),and maximal rate of left ventricular pressure of decline(-dp/dtmax);ventricular mass index(VMI) and left ventricular mass index(LVMI) were observed;the plasma levels of TNF-α were assayed by radioimmunity method;and the histopathological changes of cardiac muscles were observed under microscope.Results Compared with those of normal control group,HR,LVEDP,VMI,LVMI,and plasma TNF-α in CHF control group were significantly increased(P<0.05,or P<0.01),while ±dp/dtmax and LVSP were significantly decreased(P<0.01);collagen tissues of cardiac muscles were obviously increased,and myocardial fibrosis was found.Compared with those of CHF control group,HR,LVEDP,VMI,LVWI,and the plasma TNF-α were significantly decreased(P<0.05,or P<0.01),while LVSP and ±dp/dtmax were significantly increased(P<0.01) in groups treated with TFE and metoprolol;and myocardial fibrosis was obviously ameliorated.Conclusion TFE can improve heart function and reverse ventricular remodeling in CHF rats,which might be related with the decrement of plasma TNF-α.",
        "keywords": [
            "Ventricular remodeling",
            "Total flavonoids of Epimedium",
            "Congestive heart failure",
            "Metoprolol",
            "Tumor necrosis factor-α",
            "Isoproterenol"
        ],
        "authors": [
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Chinese PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Jia-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Chinese PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "JIAO Dong-dong",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Chinese PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Chinese PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Chinese PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2010
    },
    "ZoVkkbf4": {
        "id": "ZoVkkbf4",
        "title": "Demonstration and definition of the noncovalent binding selectivity of agents related to CC-1065 by an affinity cleavage agent: noncovalent binding coincidental with alkylation",
        "abstract": "A study of the DNA cleavage efficiency and selectivity of CDPI3-EDTA (4), an affinity cleavage agent based on the structure of CC-1065, is described. The studies with 4 provide direct evidence of AT-rich noncovalent binding coincidental with all DNA alkylation sites observed with (+)- or ent-(-)-CC-1065. Copyright (C) 1996 Elsevier Science Ltd",
        "keywords": [],
        "authors": [
            {
                "name": "Dale L. Boger",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Jiacheng Zhou",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1996
    },
    "vrgNywHg": {
        "id": "vrgNywHg",
        "title": "Thienopyrrolyl and furanopyrrolyl compounds and their use as histamine h4 receptor ligands",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "nicholas i carruthers",
                "org": ""
            },
            {
                "name": "curt a dvorak",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "annette k kwok",
                "org": ""
            },
            {
                "name": "jianmei wei",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2003
    },
    "zidI8cIE": {
        "id": "zidI8cIE",
        "title": "Urinary polyphenols and breast cancer risk: results from the Shanghai Women's Health Study.",
        "abstract": "Polyphenols, the most abundant dietary antioxidants, also possess many other anticarcinogenic activities. Urinary metabolites of polyphenols could complement dietary assessment of the bioavailability of these nutrients. We conducted a study of 353 incident breast cancer cases and 701 individually matched controls nested within the Shanghai Women's Health Study cohort of women aged 40-70 years at baseline. Liquid chromatography photo-diode array electrospray mass spectrometry was used to measure tea polyphenols (epicatechin, epigallocatechin, and their metabolites) and flavonols (e.g., quercetin and kaempferol). Multivariate conditional logistic regression analyses were used to assess associations between breast cancer risk and urinary excretion rates of polyphenols. Urinary excretion of tea polyphenols increased with increasing tea leaves consumed among controls, but not among breast cancer cases. Compared with cases, controls had higher levels of urinary total polyphenols and tea polyphenols, particularly epicatechin. In contrast, we did not find any dose-response relationship between urinary polyphenols and breast cancer risk. Urinary excretion of epicatechin was inversely associated with breast cancer risk [odds ratio (OR) and 95% confidence interval (CI) of 0.59 (0.39-0.88) for the intermediate tertile]. In spline regression, we found an overall dose-response relationship between epicatechin level and risk of breast cancer, although it was not apparent in low and middle urinary excretion range. In conclusion, high epicatechin may be related to a reduced risk of breast cancer. Further studies are warranted to confirm our findings.",
        "keywords": [
            "breast cancerurinary polyphenols � flavanolsflavonols",
            "risk",
            "liquid chromatography",
            "prospective studies",
            "confidence interval",
            "odd ratio",
            "mass spectrometry",
            "polyphenols",
            "dose response relationship",
            "tea",
            "china",
            "breast cancer",
            "case control studies"
        ],
        "authors": [
            {
                "name": "Jianfeng Luo",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NIH, Department of Health and Human Services Division of Cancer Epidemiology and Genetics, National Cancer Institute Bethesda MD USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "NIH, Department of Health and Human Services Division of Cancer Epidemiology and Genetics, National Cancer Institute Bethesda MD USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Martha J Shrubsole",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Adrian A Franke",
                "org": "University of Hawaii Cancer Research Center of Hawaii 1236 Lauhala Street Honolulu HI 96813 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Institute for Medicine and Public Health, Vanderbilt-Ingram Cancer Center Sixth Floor, Suite 600, 2525 West End Avenue Nashville TN 37203-1738 USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2010
    },
    "i4mGESNr": {
        "id": "i4mGESNr",
        "title": "Body mass index, waist-to-hip ratio and late outcomes: a report from the Shanghai Breast Cancer Survival Study.",
        "abstract": "Obesity has been well studied in relation to breast cancer survival. However, the associations of post-diagnosis obesity and late outcomes (≥5 years after diagnosis) have been much less studied. A total of 4062 5-year disease-free patients were recruited from the Shanghai Breast Cancer Survival Study, a longitudinal study of patients diagnosed during 2002-2006. Cox proportional hazard model with restricted cubic spline were used to evaluate the potential non-linear associations of post-diagnosis body mass index (BMI) and waist-to-hip ratio (WHR) with late all-cause mortality and late recurrence. While no significant association was observed for post-diagnosis BMI or WHR with late recurrence; a U-shaped association was observed for the two measures with late all-cause death. Women with BMI of 25.0 kg/m(2) or WHR of 0.83 were at the lowest risk of late all-cause mortality, whereas those with BMI beyond the range of 22.1-28.7 kg/m(2) or WHR beyond the range of 0.81-0.86 had a higher risk. ER, stage or menopausal status did not modify the effect of post-diagnosis BMI or WHR on the outcomes. In conclusion, post-diagnosis BMI and WHR, as indicators of overall and central obesity respectively, were associated with late all-cause mortality in U-shaped pattern among long-term breast cancer survivors.",
        "keywords": "",
        "authors": [
            {
                "name": "Minlu Zhang",
                "org": "Department of Biostatistics, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA."
            },
            {
                "name": "Pingping Bao",
                "org": "Department of Chronic Non-Communicable Disease Surveillance, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People's Republic of China."
            },
            {
                "name": "Wanghong Xu",
                "org": "Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, People's Republic of China."
            },
            {
                "name": "Guoyou Qin",
                "org": "Department of Biostatistics, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, People's Republic of China. gyqin@fudan.edu.cn."
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, USA."
            },
            {
                "name": "Ying Zheng",
                "org": "Department of Cancer Control and Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People's Republic of China. zhengying@fudan.edu.cn."
            }
        ],
        "venue": "Scientific reports",
        "year": 2017
    },
    "MZDllVtT": {
        "id": "MZDllVtT",
        "title": "A pooled analysis of post‐diagnosis lifestyle factors in association with late estrogen‐receptor positive breast cancer prognosis",
        "abstract": "",
        "keywords": [
            "cohort",
            "breast cancer"
        ],
        "authors": [
            {
                "name": "sarah nechuta",
                "org": "vanderbilt university"
            },
            {
                "name": "w y chen",
                "org": "brigham and women s hospital"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "elizabeth m poole",
                "org": "brigham and women s hospital"
            },
            {
                "name": "marilyn l kwan",
                "org": "kaiser permanente"
            },
            {
                "name": "shirley w flatt",
                "org": "university of california"
            },
            {
                "name": "ruth e patterson",
                "org": "university of california"
            },
            {
                "name": "john p pierce",
                "org": "university of california"
            },
            {
                "name": "bette j caan",
                "org": "kaiser permanente"
            },
            {
                "name": "x o shu",
                "org": "vanderbilt university"
            }
        ],
        "venue": "International Journal of Cancer",
        "year": 2015
    },
    "jUtP5jZn": {
        "id": "jUtP5jZn",
        "title": "Morphological evolution of China's traditional commercial streets",
        "abstract": "The formation of China’s traditional commercial streets origins from residential areas and relies more on the support of consumption.Mixed commercial and residential space provides the foundation for all kinds of commercial forms.The building structure of shop in front homes (houses) fully reflects the spatial characteristics of urban and society which born in the context of small-peasant economy.With thousands of years’ evolution,traditional commercial streets have produced unique space system and created interesting space paradigm.This article reveals the morphological evolution of traditional commercial streets from the perspective of landscape,cultural values and urban paradigm.",
        "keywords": [
            "space systems",
            "block",
            "mall",
            "traditional commercial streets"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ""
            },
            {
                "name": "DUAN Xi-ying",
                "org": ""
            }
        ],
        "venue": "Urban Problems",
        "year": 2010
    },
    "11VZ79NO": {
        "id": "11VZ79NO",
        "title": "Adherence to Dietary Recommendations Among Long-Term Breast Cancer Survivors and Cancer Outcome Associations.",
        "abstract": "Background: Adherence to dietary recommendations has been shown to be associated with reduced mortality in healthy populations. Little is known about the possible benefits of adherence to dietary recommendations among breast cancer survivors. Methods: Dietary information was collected using food frequency questionnaires at the 5-year postdiagnosis survey in 3,450 5-year breast cancer survivors from the Shanghai Breast Cancer Survival Study. Adherence scores to Chinese Food Pagoda (CHFP)-2007, CHFP-2016, modified Dietary Approaches to Stop Hypertension (DASH), and Healthy Eating Index 2015 (HEI-2015) were created. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for total mortality and breast cancer-specific events according to adherence scores. Results: Participants in the highest quartiles of CHFP-2007, CHFP-2016, and DASH had 25% to 34% lower risk of total mortality (HR, 0.66; 95% CI, 0.48-0.89 for CHFP-2007; HR, 0.75; 95% CI, 0.55-1.01 for CHFP-2016; HR, 0.66; 95% CI, 0.49-0.91 for DASH), and 36% to 40% lower risk of breast cancer-specific events (HR, 0.64; 95% CI, 0.44-0.93 for CHFP2007; HR, 0.67; 95% CI, 0.45-0.99 for CHFP-2016; HR, 0.60; 95% CI, 0.40-0.90 for DASH) comparing with the lowest quartiles. Associations did not vary by known prognostic factors. HEI-2015 scores were not significantly associated with breast cancer outcomes. Conclusions: Higher adherence to CHFP and DASH dietary guidelines post-cancer diagnosis was associated with reduced risk of both overall death and breast cancer-specific recurrence or death among long-term breast cancer survivors. Impact: Our study highlights the importance of overall dietary quality among long-term breast cancer survivors.",
        "keywords": "",
        "authors": [
            {
                "name": "Fei Wang",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN USA"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Liang Shi",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Danxia Yu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN USA"
            },
            {
                "name": "Minlu Zhang",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN USA"
            },
            {
                "name": "Ying Zheng",
                "org": "Fudan Univ, Shanghai Canc Ctr, Dept Canc Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol,Dept Med,Vanderbilt Epidemiol Ctr, Nashville, TN USA"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2020
    },
    "l0XCBfMO": {
        "id": "l0XCBfMO",
        "title": "Validity and reproducibility of the food-frequency questionnaire used in the Shanghai men's health study.",
        "abstract": "We evaluated the validity and reproducibility of the FFQ used in the Shanghai Men's Health Study (SMHS). The study included 195 randomly selected participants of the SMHS who completed one FFQ at baseline, twelve 24-hour dietary recalls (24-HDR) (once a month for twelve consecutive months) and a second FFQ at the end of the study. The FFQ accounted for 8878 % of the foods recorded in the 24-HDR surveys. The validity of the FFQ was evaluated by comparing nutrient and food group intake levels from the second FFQ and the multiple 24-HDR. Correlation coefficients ranged from 038 to 0.64 for macronutrients, 033 to 0.58 for micronutrients and 035 to 0.72 for food groups. Misclassification to opposite quartiles for nutrients and food groups was rare, ranging from 1.5 to 7.7%, while exact agreement rates were between 31.8 and 533 %. The reliability of the FFQ was assessed by comparing the intake levels from the two FFQ. Correlation coefficients were 0.39 to 0.53 for macronutrients, 0.38 to 0.52 for micronutrients and 0.39 to 0.64 for food groups. Exact agreement rates for quartile distribution were between 31.8 and 49.2 %, while misclassification to opposite quartiles was between 1.5 and 6.2 %. These data indicate that the SMHS FFQ can reasonably categorise usual intake of nutrients and food groups among men living in urban Shanghai.",
        "keywords": [
            "food-frequency questionnaire",
            "validity",
            "reliability"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "DaKe Liu",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            }
        ],
        "venue": "BRITISH JOURNAL OF NUTRITION",
        "year": 2007
    },
    "tIFbDWXa": {
        "id": "tIFbDWXa",
        "title": "Influence of adjuvant-induced arthritis rat behavioral characteristics and TNF-α expression in synovium with sinomenine treatment",
        "abstract": "Objective To investigate the influence of sinnomenine on joint pain and synovium inflammation in adjuvant-induced arthritis rats.Methods 40 rats were randomly divided into control group(n=10)and adjuvant-induced group(n=30).After being modeled,the rats in adjuvant-induced group were randomly divided into model group(n=10),sinnomenine group(n=10) and methotrexate group(n=10).From the second day of modeling success,sinomenine group and methotrexate group were given sinomenine and methotrexat intervention for 4 weeks respectively.The behavioral characteristics of rats were observed.HE staining was used to observe synovium pathological changes,ELISA was used to measure the expression of TNF-α in synovium.Results Compared with normal group,pain threshold was significantly lower and TNF-α expressions in synovium were significantly increased in model group(all P<0.01).Compared with the model group,pain threshold and TNF-α expression were statistically different in methotrexate group and sinomenine group(all P<0.05).Conclusions SIN could improve the joint pain,decrease TNF-α expression in synovium,and improve the pathological changes;which may be one of its mechanism of action in the treatment of rheumatoid arthritis.",
        "keywords": [
            "sinomenine",
            "arthritis",
            "pain",
            "tumor necrosis factor-α",
            "rats"
        ],
        "authors": [
            {
                "name": "MU Hui",
                "org": "School of Medicine,Second Military Medical University,Nanjing ,P.R.China"
            },
            {
                "name": "CAI Hui",
                "org": "School of Medicine,Second Military Medical University,Nanjing ,P.R.China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "School of Medicine,Second Military Medical University,Nanjing ,P.R.China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "School of Medicine,Second Military Medical University,Nanjing ,P.R.China"
            }
        ],
        "venue": "Shandong Medical Journal",
        "year": 2013
    },
    "YzTD4e9g": {
        "id": "YzTD4e9g",
        "title": "Intake of specific nonfermented soy foodsmay be inversely associated with risk of distal gastric cancer in a Chinese population",
        "abstract": "Because the association between soy consumption and gastric cancer is inconsistent, we evaluated the putative preventive effect of soy food on gastric cancer risk in the Shanghai Women's and Men's Health Studies, comprising a total of 128,687 participants. Intake of nonfermented soy foods was estimated using 2 validated food-frequency questionnaires. HRs were calculated with 95% CIs for intake amounts of total nonfermented soy food intake, soy protein, and isoflavones as well as individual soy food groups using Cox proportional hazards regression. A total of 493 distal gastric cancer cases were identified by 2010. Although all risk estimates for summary measures of soy food intake above the lowest quartile (quartile 1) were suggestive of a protective effect, no statistically significant associations with risk of distal gastric cancer were found. Among the separate soy food groups, significant reductions in risk of distal gastric cancer by increasing intake of tofu were found in men in quartile 2 (HR: 0.59; 95% CI: 0.40, 0.86), quartile 3 (HR: 0.62; 95% CI: 0.44, 0.88), and quartile 4 (HR: 0.64; 95% CI: 0.42, 0.99), resulting in a significant trend (P-trend = 0.02). Dry bean intake was also inversely associated with decreased risk of gastric cancer, but in postmenopausal women only [quartile 2 (HR: 0.54; 95% CI: 0.30, 0.96); quartile 3 (HR: 0.90; 95% CI: 0.64, 1.27); and quartile 4 (HR: 0.63; 95% CI: 0.43, 0.91)], resulting in a significant trend (P-trend = 0.03). Overall, our study found no statistically significant association between nonfermented soy food intake and distal gastric cancer risk, though the data supported the hypothesis that tofu may protect against distal gastric cancer in men and dry bean consumption may decrease the risk of gastric cancer in postmenopausal women. © 2013 American Society for Nutrition.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Sun-Seog Kweon",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Yongbing Xiang",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Honglan Li",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Yutang Gao -",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Meira Epplein",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "The Journal of nutrition",
        "year": 2013
    },
    "66bU6CiV": {
        "id": "66bU6CiV",
        "title": "Synthesis and evaluation of deglycobleomycin A2 analogues containing a tertiary N-methyl amide and simple ester replacement for the l-histidine secondary amide: Direct functional characterization of the requirement for secondary amide metal complexation",
        "abstract": "The synthesis and comparative examination of 3-5, analogues of deglycobleomycin A(2) (2) which address the inferred importance of the L-histidine secondary amide directly, are detailed. The agent 3 lacks only the L-histidine beta-hydroxy group of deglycobleomycin A(2) and the corresponding agents 4 and 5 incorporate a tertiary N-methyl amide and simple ester in place of the L-histidine secondary amide. The DNA cleavage properties of 3 proved essentially indistinguishable from those of deglycobleomycin A(2) (2) confirming that the distinctions between bleomycin A(2) (1) and deglycobleomycin (2) are due to the removal of the disaccharide and not the introduction of the L-histidine free beta-hydroxy group. The agents 4 and 5 containing a tertiary N-methyl amide and ester in place of the L-histidine secondary amide were found to cleave duplex DNA but to do so in a nonsequence selective fashion with a substantially reduced efficiency and a diminished double to single strand cleavage ratio that are only slightly greater than that of free iron itself. These latter observations establish the functional requirement for the L-histidine secondary amide and are consistent with the proposals that the L-histidine deprotonated secondary amide is required for functional metal chelation and activity.",
        "keywords": [
            "iron"
        ],
        "authors": [
            {
                "name": "Dale L. Boger",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Shuji Teramoto",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1996
    },
    "fcJkZkaT": {
        "id": "fcJkZkaT",
        "title": "Physical activity, smoking, and alcohol consumption in association with incidence of type 2 diabetes among middle-aged and elderly Chinese men.",
        "abstract": "Type 2 diabetes mellitus (T2DM) is a prevalent chronic disease worldwide. The prevalence of T2DM is increasing rapidly in China. Understanding the contribution of modifiable lifestyle factors on T2DM risk is imperative to prevent the development of T2DM in China.We examined associations between lifestyle factors including physical activity, smoking and alcohol consumption with incidence of T2DM among middle-aged and elderly men in urban Shanghai. Information on socio-demographics, lifestyle habits, dietary habits, and disease history was collected via in-person interviews. Anthropometric measurements were taken. A total of 51 464 Chinese men aged 40-74 years free of T2DM, coronary heart disease (CHD), and stroke at baseline were included in the current study. Incident T2DM was identified through follow-up surveys conducted every 2-3 years. Cox proportional hazard analyses were conducted to evaluate associations between lifestyle risk factors and incidence of T2DM.We documented 1304 new cases of T2DM during 276 929 person-years of follow-up (average: 5.4 years). Physical activity was inversely associated with T2DM risk. Daily living, commuting, and total physical activity METs had inverse negative dose-response relationships with T2DM (P-trend = 0.0033, 0.0022, and <0.0001, respectively). Regular participation in exercise or sports reduced T2DM risk (HR = 0.86, 95%CI: 0.76-0.98). Moderate alcohol intake (1-3 drinks/day) was inversely related to T2DM risk (HR = 0.80, 95%CI: 0.67-0.94). Cigarette smoking, on the other hand, was associated with increased T2DM risk; HRs were 1.25 (95%CI: 1.00-1.56) for smoking more than 20 cigarettes per day and 1.28 (95%CI: 1.04-1.57) for smoking more than 40 pack-years.Physical activity and moderate alcohol intake are inversely associated with T2DM risk, whereas smoking was positively associated with T2DM risk among middle-age and elderly Chinese men. Preventive measures should be developed to focus on these modifiable lifestyle habits to reduce the upward trend of T2DM.",
        "keywords": [
            "physics",
            "incidence",
            "proportional hazards models",
            "china",
            "medicine",
            "biology",
            "engineering",
            "chemistry",
            "risk factors"
        ],
        "authors": [
            {
                "name": "Liang Shi",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Qiaolan Liu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt University Medical Center(Vanderbilt Medical Center,Vanderbilt University Medical Center),Nashville,United States"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "2NEmJ68o": {
        "id": "2NEmJ68o",
        "title": "Adolescent Exercise in Association with Mortality from All Causes, Cardiovascular Disease, and Cancer among Middle-Aged and Older Chinese Women",
        "abstract": "Background: Little is known regarding the role of early-life exercise, a potentially modifiable factor, in long-term adult morbidity and mortality. We utilized the Shanghai Women's Health Study (SWHS) to investigate adolescent exercise in association with cancer, cardiovascular disease (CVD), and all-cause mortality among middle-aged and older women. Methods: The SWHS is a prospective cohort of 74,941 Chinese women ages 40 to 70 years recruited from 1996 to 2000. In-person interviews at enrollment assessed adolescent and adult exercise history, medical and reproductive history, and other lifestyle and socioeconomic (SES) factors. Mortality follow-up occurs via annual linkage to the Shanghai Vital Statistics Registry. Adjusted hazard ratios (HR) and 95% confidence intervals (CI) were derived from Cox regression models. Results: Adjusting for birth year and other adolescent factors, adolescent exercise was associated with reduced risk of cancer, CVD, and total mortality [HRs (95% CI), 0.83 (0.72-0.95), 0.83 (0.70-0.98), and 0.78 (0.71-0.85), respectively for <= 1.33 hours (h)/week, and 0.83 (0.74-0.93), 0.62 (0.53-0.72), and 0.71 (0.66-0.77), respectively for > 1.33 h/week (reference = none)]. Results were attenuated after adjustment for adult SES and lifestyle factors. Participation in sports teams was inversely associated with cancer mortality [HR (95% CI), 0.86 (0.76-0.97)]. Joint adolescent and adult exercise was associated with reduced risk of all-cause, CVD, and cancermortality [HRs (95% CIs), 0.80 (0.72-0.89), 0.83 (0.691.00), and 0.87 (0.74-1.01), respectively], adjusting for adult/adolescent factors, and adolescence exercise only was inversely associated with cancer mortality [HR (95% CI), 0.84 (0.71-0.98)]. Conclusions: Adolescent exercise participation, independent of adult exercise, was associated with reduced risk of cancer, CVD, and all-cause mortality. Impact: Results support promotion of exercise in adolescence to reduce mortality in later life. (C) 2015 AACR.",
        "keywords": [
            "chinese",
            "sport",
            "ethnic groups",
            "cohort studies",
            "risk reduction"
        ],
        "authors": [
            {
                "name": "sarah nechuta",
                "org": "Vanderbilt Epidemiol Ctr, Dept Med, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "x o shu",
                "org": "Vanderbilt Epidemiol Ctr, Dept Med, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "g yang",
                "org": "Vanderbilt Epidemiol Ctr, Dept Med, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "hui cai",
                "org": "Vanderbilt Epidemiol Ctr, Dept Med, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "y gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "honglan li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "yongbing xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "wei zheng",
                "org": "Vanderbilt Epidemiol Ctr, Dept Med, Div Epidemiol, Nashville, TN USA"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2015
    },
    "WpQ5DTNw": {
        "id": "WpQ5DTNw",
        "title": "Effect of Acupuncture on Insulin Receptor Gene Expression of Adipose Tissue in Type 2 Diabetes Mellitus",
        "abstract": "Objective To observe effects of acupuncture on the expression of insulin receptor gene(INSR) mRNA of adipocytes in rats with type 2 diabetes mellitus(T2DM).Methods The rat model of T2DM was induced by intraperitoneal injection of small dosage streptozotocin in rats with diet-induced obesity.Then these T2DM rats were averagely randomized into acupuncture group,Glibenclamide group and model group,and normal rats were used as control.After treatment for 4 weeks,fasting blood sugar(FBS) was assayed with active blood sugar meter;Fasting insulin(FINS) was assayed by radioimmunoassay;The expression of INSR mRNA of adipocytes was evaluated using in situ hybridization.Results After treatment,serum levels of FBS,FINS,ISI and Homa-IR in the model group were significantly higher than those in the control group(P<0.01),with the expression of INSR mRNA of adipocytes being significantly decreased(P<0.01).After treatment,serum levels of FBS,FINS,ISI and Homa-IR in acupuncture group and Glibenclamide group were significantly decreased compared with those in the model group(P<0.05,or P<0.01),with the expression of INSR mRNA being significantly increased(P<0.01).After treatment,the serum level of FINS in acupuncture group was significantly decreased compared with that in Glibenclamide group(P<0.01),with the expression of INSR mRNA of adipocytes being significantly increased(P<0.01).Conclusion In rats with T2DM,the expression of INSR mRNA of adipocytes is decreased,both acupuncture and Glibenclamide can upregulate the expression of INSR mRNA of adipocytes,and acupuncture is superior to Glibenclamide in improving the expression of INSR mRNA of adipocytes.",
        "keywords": [
            "Gene expression",
            "Acupuncture",
            "Type 2 diabetes mellitus",
            "Adipocytes",
            "Glibenclamide",
            "Insulin receptor"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrative Traditional Chinese and Western Medicine,the General Hospital of Nanjing Military Area of PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": "Department of Integrative Traditional Chinese and Western Medicine,the General Hospital of Nanjing Military Area of PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "WEI Qun-li",
                "org": "Department of Integrative Traditional Chinese and Western Medicine,the General Hospital of Nanjing Military Area of PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "LIU Zhi-cheng",
                "org": "the Second Clinical Medicine College,Nanjing University of Traditional Chinese Medicine,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2010
    },
    "hio9ab8H": {
        "id": "hio9ab8H",
        "title": "Study on multi-scale AMSS operator for fabric flaw detection",
        "abstract": "Focused on fabric flaw detection, an improved AMSS operator based on multi-scale and iterative method was presented. The AMSS equation was discreted with finite difference, and according to quantitative scale parameter t and scale step length Δt, the noise in the object image was iteratively filtered by small scale step length, then aimed at the filter result of AMSS operator, a new evaluation method on level line was introduced. The experimental result illustrates that this improved operator can efficiently keep edge information, and the performance of filting noise is more effective than other methods for image mixed with multi-noise.",
        "keywords": [
            "AMSS operator",
            "Flaw detection",
            "Image filter",
            "PDEs"
        ],
        "authors": [
            {
                "name": "ZHANG Guang-xin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "CAI Jin-hui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Chinese Journal of Sensors and Actuators",
        "year": 2006
    },
    "giRcRGRD": {
        "id": "giRcRGRD",
        "title": "Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors",
        "abstract": "Noncovalent, potent, selective and orally bioavailable inhibitors of the cysteine protease cathepsin S are reported.",
        "keywords": [
            "Cathepsin S",
            "Cysteine protease inhibitor"
        ],
        "authors": [
            {
                "name": "Darin J. Gustin",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Clark A. Sehon",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Jianmei Wei",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Hui Cai",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Steven P. Meduna",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Haripada Khatuya",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Siquan Sun",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Yin Gu",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Wen Jiang",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Robin L. Thurmond",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Lars Karlsson",
                "org": "Johnson and Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "James P. Edwards",
                "org": "Corresponding author. Tel.: +1 8584502024; fax: +1 8587843116"
            }
        ],
        "venue": "Bioorganic & Medicinal Chemistry Letters",
        "year": 2005
    },
    "16l5pG35": {
        "id": "16l5pG35",
        "title": "Dietary patterns and blood pressure among middle-aged and elderly Chinese men in Shanghai.",
        "abstract": "The prevalence of hypertension has increased over the past decade in many developed and developing countries, including China. This increase may be associated with changes in lifestyle, including dietary patterns. We evaluated the association of dietary patterns with blood pressure (BP) by using data from a large, population-based cohort study of middle-aged and elderly Chinese men, the Shanghai Men's Health Study. The present cross-sectional analysis includes 39 252 men who reported no prior history of hypertension, diabetes, CHD, or stroke nor use of antihypertensive drugs at study enrolment. Three dietary patterns, 'vegetable', 'fruit and milk' and 'meat', were derived using factor analysis. The fruit and milk diet was inversely associated with both systolic and diastolic BP (P-trend < 0.001). The adjusted mean systolic BP was 2.9 mmHg lower (95% CI -3.4, -2.4), and diastolic BP was 1.7 mmHg lower (95% CI -2.0, -1.4) for men in the highest quintile of the 'fruit and milk' pattern compared with men in the lowest quintile. This inverse association was more evident among heavy drinkers; the highest quintile of the 'fruit and milk' pattern was associated with a 4.1 mmHg reduction in systolic BP v. a 2.0 mmHg reduction among non-drinkers (P-interaction = 0.003) compared to the lowest quintile. The corresponding reductions in diastolic BP were 2.0 v. 1.3 mmHg (P-interaction = 0.011). The 'fruit and milk' pattern was associated with a lower prevalence of both pre-hypertension and hypertension, and the associations appeared to be stronger among drinkers. Results of the present study suggest an important role for diet in the prevention of hypertension.",
        "keywords": [
            "Dietary patterns",
            "Blood pressure",
            "Hypertension",
            "Chinese men",
            "Alcohol consumption",
            "Smoking"
        ],
        "authors": [
            {
                "name": "Sang-Ah Lee",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Shanghai Jiao Tong Univ, Shanghai Canc Inst, Dept Epidemiol, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiao Tong Univ, Shanghai Canc Inst, Dept Epidemiol, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Jiao Tong Univ, Shanghai Canc Inst, Dept Epidemiol, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Shanghai Canc Inst, Dept Epidemiol, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "BRITISH JOURNAL OF NUTRITION",
        "year": 2010
    },
    "Agp1BS43": {
        "id": "Agp1BS43",
        "title": "Research Progress of Atherosclerosis risk factors on Patients with Rheumatoid Arthritis",
        "abstract": "The patients with rheumatoid arthritis posses higher disease incidence for atherosclerosis,also posses higher mortality than the general patients.Atherosclerosis control can reduce mortality and improve the quality of life.In this paper,the traditional risk factors,inflammation,vascular endothelial dysfunction,lipid metabolism,insulin resistance,high Hyperhomocysteinemia aspects are reviewed.",
        "keywords": [
            "Rheumatoid arthritis",
            "Artherosclerosis",
            "Review",
            "Risk factor"
        ],
        "authors": [
            {
                "name": "ZHENG Zhao-ling",
                "org": "Nanjing General Hospital of Nanjing Military Command,Jiangsu,,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Jiangsu,,China"
            }
        ],
        "venue": "Occupation and Health",
        "year": 2008
    },
    "DlGtuKmH": {
        "id": "DlGtuKmH",
        "title": "Second Vienna International Vocal Competition launched",
        "abstract": "The Second Vienna International Vocal Competition launched on March 22,2010 in Beijing,with a press conference headed by Guo Zhikai.The competition will be held in Vienna in July this year.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "Lkcfgv1E": {
        "id": "Lkcfgv1E",
        "title": "The Analysis on Susceptibility of LDL to in Vitro Oxidation and in Vivo Oxidized LDL Levels in Patients with Rheumatoid Arthritis",
        "abstract": "Objective To investigate plasma oxidized low density lipoprotein (ox-LDL) level and susceptibility of LDL to in vitro oxidation,and the relationship between them in patients (pts) with rheumatoid arthritis (RA).Method LDL in 23 pats with RA and 25 control subjects was isolated using preparative ultra-centrifugation.The susceptibility of LDL to Cu2+-mediated oxidation was analyzed by absorbance measurements at 234 nm.ox-LDL was detected by ELISA.Results The lag time,maximal oxidation rate and total amount of conjugated dienes of LDL oxidizability in RA pts were significantly different from that in control group.ox-LDL levels in RA pts were significantly higher than that in controls (P<0.01).ox-LDL level was correlated with the lag time of LDL in pts with RA (r=-0.55,P<0.01).Conclusion LDL in pts with RA was more susceptible to oxidative modification and plasma ox-LDL was increased,which might play the role in the development of atherosclerosis.",
        "keywords": [
            "LDL",
            "oxidized modification",
            "rheumatoid arthritis",
            "atherosclerosis"
        ],
        "authors": [
            {
                "name": "Hu Bing",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Southern Medical University%%#Nanjing %%#"
            },
            {
                "name": "Wang Junjun",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Southern Medical University%%#Nanjing %%#"
            },
            {
                "name": "Cai Hui",
                "org": " Department of Integrated Traditional Chinese and Western Medicine,Southern Medical University%%#Nanjing %%#"
            }
        ],
        "venue": "Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease",
        "year": 2009
    },
    "M4JCDHYA": {
        "id": "M4JCDHYA",
        "title": "T'ai chi as exercise among middle-aged and elderly Chinese in urban China",
        "abstract": "Objectives: T'ai chi is a form of mind-body practice used as exercise in China, though limited data are available on characteristics of t'ai chi users and factors associated with practice. Methods: Characteristics of and factors associated with t'ai chi practice among middle-aged and elder Chinese in Shanghai China were analyzed utilizing baseline data from the Shanghai Women's Health Study and Shanghai Men's Health Study. Logistic regression modeling was used to identify independent factors associated with the practice of t'ai chi among men and women. Results: T'ai chi is the most common form of regular exercise in Shanghai China among middle-aged and elderly persons (22%), including among women (28%) and men (15%). Other popular forms of exercise were walking (7%), dancing (4%), and jogging (3%). A majority of adults who practiced t'ai chi used it as their exclusive type of exercise (69%). Overall, t'ai chi practitioners as compared to nonpractitioners were more likely women, older, more educated, retired versus still working, and more likely to report chronic medical conditions including pulmonary, gastrointestinal, and cardiovascular conditions. T'ai chi activity was associated with other health behaviors including nonsmoking, consuming ginseng, and participating in other forms of physical exercise. Conclusions: T'ai chi is the predominant form of exercise among middle-aged and elderly Chinese in urban China, particularly among those with older age and chronic medical diseases. Future research is needed to see whether t'ai chi has similar or different benefits than conventional forms of exercise such as walking and jogging.",
        "keywords": [
            "cohort studies",
            "china",
            "age distribution"
        ],
        "authors": [
            {
                "name": "Gurjeet S. Birdee",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Div Gen Internal Med & Pediat, Nashville, TN 37232 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN 37232 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN 37232 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Yutang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN 37232 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol, Nashville, TN 37232 USA"
            }
        ],
        "venue": "JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE",
        "year": 2013
    },
    "knTG2l66": {
        "id": "knTG2l66",
        "title": "Genetic Variation of Helicobacter pylori in the Oral Cavity and Stomach Detected Using TA-Cloning in Children with chronic Gastritis.",
        "abstract": "Objectives: To investigate the DNA sequence variations of Helicobacter pylori in the oral cavities and stomachs of children with chronic gastritis. Methods: Dental plaques and gargle on 235 patients were obtained before gastroscopy. Gastric H. pylori infection was diagnosed using rapid urease test or Giemsa staining. H. pylori 16S rDNA and CagA gene were analyzed using PCR methods. Thymine adenine cloning-based sequencing was performed in patients with CagA gene positive from oral cavities. The sequence alignments and V1 variable region were evaluated by comparison with the sequence of the standard H. pylori 26695 strain. Results: Totally, 46 out of the 235 patients were positive for gastric H. pylori infection. Of the 46 patients, 26 cases had amplified H. pylori 16S rDNA in both oral (plaque and gargle) and gastric samples. Of the 26 cases, 12 patients (46.1%) were positive for the H. pylori CagA gene in the oral samples, which was significantly lower than that in the gastric mucosa (80.8%; P = 0.010). The homology of the complete sequence alignment ranged from 74.0% to 92.1% in the oral and gastric samples. The V1 region alleles (positions 75-99) had 7-22 polymorphisms (homology from 12.0% to 72.0%) in 11 patients between the oral and gastric samples, but had 100% homology in 1 patient. Conclusions: Our study found that distinct H. pylori strains exist in the oral cavities of children, but we would not support the hypothesis that H. pylori in the oral cavities is an important reservoir of gastric H. pylori infections in children.",
        "keywords": [
            "Helicobacter pylori",
            "genetic variation",
            "gastric mucosa",
            "dental plaque",
            "children"
        ],
        "authors": [
            {
                "name": "hui cai",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            },
            {
                "name": "wei li",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            },
            {
                "name": "xiaoou shu",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            },
            {
                "name": "k peng",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            },
            {
                "name": "yuehui zhang",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            },
            {
                "name": "ming jiang",
                "org": "Zhejiang Univ, Childrens Hosp, Dept Gastroenterol, Sch Med, Hangzhou 310003, Zhejiang, Peoples R China"
            }
        ],
        "venue": "PEDIATRIC INFECTIOUS DISEASE JOURNAL",
        "year": 2014
    },
    "DbOs7NtW": {
        "id": "DbOs7NtW",
        "title": "Review on the Relationship between Calcineurin-nuclear Factors of Activated T Cells(CaN-NFAT) Signal Channel and Systemic Lupus Erythematosus(SLE)",
        "abstract": "SLE is a self immunopathy attacking multi-organs featured with much autoantibody,with unknown pathogenesis;presently it is viewed that abnormal T lymphocyte is the key of SLE occurrence.CaN-NFAT is the important bio-signal transfer access in T cell,with the regulation hinge to T cell activation.The article makes review on such signal pathway in SLE development and present main medications status,offering foundation for SLE basic study and clinical treatment.",
        "keywords": [
            "Cyclosporine",
            "Tacrolimus",
            "SLE",
            "CaN-NFAT"
        ],
        "authors": [
            {
                "name": "Zhang Qunyan",
                "org": " Nanjing General Hospital of Nanjing Military Zone,Jiangsu%%#%%#"
            },
            {
                "name": "Cai Hui",
                "org": " Nanjing General Hospital of Nanjing Military Zone,Jiangsu%%#%%#"
            }
        ],
        "venue": "Journal of Zhejiang Chinese Medical University",
        "year": 2012
    },
    "kPMOWG5y": {
        "id": "kPMOWG5y",
        "title": "Aging, obesity, and post-therapy cognitive recovery in breast cancer survivors.",
        "abstract": "Therapy-induced cognitive impairment is prevalent and long-lasting in cancer survivors, but factors affecting post-therapy cognitive recovery are unclear. We conducted this study to evaluate the associations of age, body mass index (BMI), waist-to-hip ratio (WHR), and physical activity (PA) with post-therapy cognitive changes in a population-based breast cancer (BC) survivor cohort. We collected information on PA, weight, height, waist and hip circumferences of 1286 BC survivors aged 20-75. We assessed their cognitive functions, including immediate memory, delayed memory, verbal fluency, and attention, at 18 and 36 months after cancer diagnosis. Linear regression models were used to examine the associations of age, BMI, WHR and PA with mean changes in cognitive scores from 18- to 36-month follow-up interview. We found that the post-therapy cognitive changes differed by age and obesity status. Verbal fluency and attention improved in younger patients aged <60 and non-abdominally obese patients, but deteriorated in older patients aged ≥60 (i.e. verbal fluency and attention) and abdominally obese patients (i.e. verbal fluency). Memory improved in all patients, with a smaller improvement in obese patients compared with normal-weight patients. No significant association was found between PA and post-therapy cognitive change. Due to the novelty of our findings and the limitations of our study, further research, including intervention trials, is warranted to confirm the causal relationship between obesity and cognitive impairments.",
        "keywords": [
            "age",
            "breast cancer survivor",
            "cognitive",
            "obesity",
            "physical activity"
        ],
        "authors": [
            {
                "name": "Zhezhou Huang",
                "org": "Department of Elderly Health, Division of Noncommunicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Ying Zheng",
                "org": "Department of Cancer Control and Prevention, Division of Noncommunicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Pingping Bao",
                "org": "Department of Noncommunicable Disease Surveillance, Division of Noncommunicable Disease and Injury, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            },
            {
                "name": "Zhen Hong",
                "org": "Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Ding Ding",
                "org": "Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "James Jackson",
                "org": "Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Department of Medicine, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            },
            {
                "name": "Qi Dai",
                "org": "Department of Medicine, Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            }
        ],
        "venue": "Oncotarget",
        "year": 2017
    },
    "iGdBL8Er": {
        "id": "iGdBL8Er",
        "title": "Effects of curcumin on the expressions of TNF-α and IL-1β in the synovia and serum of adjuvant arthritis rats",
        "abstract": "Objective: To explore the possible mechanism of curcumin acting on rheumatoid arthritis(RA) by detecting the expressions of TNF-α and IL-1β in the synovia and serum of adjuvant arthritis(AA) rats,and to find theoretical and experimental evidence for the clinical application of curcumin to the treatment of RA.Methods: Thirty healthy experimental SD rats were randomly divided into 3 groups of equal number: a control,a model and a curcumin group.The AA models were established by intradermal injection of Freund's complete adjuvant(FCA).At 15 days,the blood and articular genu rinse solution were collected from the rats for the detection of the expressions of TNF-α and IL-1β in the synovia and serum by ELISA.Results: The expressions of TNF-α and IL-1β in the synovia and serum were significantly higher in the AA model rats than in the control(P< 0.05) and the curcumin group(P< 0.05).Conclusion: Curcumin can inhibit the abnormal secretion of TNF-α and IL-1β and suppress the development of immune inflammation in AA rats,which may be the mechanism of its action on rheumatoid arthritis.",
        "keywords": [
            "TNF-α",
            "Synovial fluid",
            "Curcumin",
            "Serum",
            "Adjuvant arthritis",
            "IL-1β"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHENG Zhao-ling",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "O1N9Va2P": {
        "id": "O1N9Va2P",
        "title": "Shanghai Opera House issues its first album Fantastic Harmony",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2009
    },
    "EO4XGIfK": {
        "id": "EO4XGIfK",
        "title": "Reversing effect of captopril on left ventricular remodeling in rats with increased pressure load",
        "abstract": "BACKGROUND: Pressure overload can lead to the activation of renin-angiotensin-aldosterone system, and then left ventricular remodeling occurs. Captopril can reverse this progress.OBJECTIVE: To observe the effect of captopril in reversing left ventricular remodeling in rats with pressure overload and to elucidate its possible mechanism.DESIGN: A randomized controlled trial.SETTING: Department of Integrated Traditional Chinese Medicine and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA; Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine; Postdoctor Institute of Hebei Medical University. MATERIALS: The experiment was conducted in the Laboratory of Shanghai University of Traditional Chinese Medicine between January 1998 and October 1998. Totally 153 male Wistar rats were recruited. There were 5 experiments, 36 rats in each experiment except 9 rats in the fourth one. METHODS: A total of 36 Wistar male rats selected for each experiment were randomly divided into sham operation group, model group and captopril group. Rats in model group received modeling for 4 weeks, then gastric perfusion with 15 mL/kg of distilled water once per day for 4 consecutive weeks. Abdominal aorta of the rats in sham-operation group were separated without closure by sliver clip, then 4 weeks later the procedure was the same as that in model group. In captopril group, 4 weeks after modeling, the rats were performed gastric perfusion with diluted captopril of 100 mg/kg, once a day for 4 consecutive weeks. MAIN OUTCOME MEASURES: The effect of captopril on left ventricular mass index (LVMI), mRNA expression of collagen typeⅠand Ⅲ, content of plasma angiotensinⅡ(AngⅡ) and left ventricular tissue AngⅡ, plasma atrial natriuretic factor (ANF), and serum aldosterone (ALD) level.RESULTS: Totally 153 rats entered the result analysis. During the test for detecting the absorbance (A) of collagen typeⅠ, 3 rats in sham operation group and 3 in captopril group died, and 1 rat died in model group; finally 29 rats were involved. During the test for detecting the absorbance (A) of collagen type Ⅲ, 3 rats died in sham operation group, 4 rats died in model group, and 2 rats died in captopril group; finally 27 rats were involved. All the rats were lost due to operation injury. 1 Comparison of LVMI: LVMI in sham operation group and captopril group was lower than that in model group (2.24±0.12)/1 000, (2.67±0.40) /1 000, (3.15±0.47)/1 000, t=2.649, 6.499, P < 0.001, 0.05 . 2 Change of A of collagen type I: It was significantly lower in sham operation group and captopril group than in model group (0.57±0.19, 0.86±0.25, 2.79±2.00), t=3.661, 3.170, P < 0.01, 0.05 . 3 Change of A of collagen type Ⅲ: It was significantly lower in sham operation group and captopril group than in model group (0.48±0.10, 0.52±0.29, 0.84±0.27), t=3.560, 2.417, P < 0.01, 0.05 . 4 The expression of mRNA of collagen type I: It was significantly lower in sham operation group and captopril group than in model group (79.1±18.6)%, (51.7±16.0)%, (139.0±29.2)%, t=2.910, P < 0.05 . 5 Comparison of plasma AngⅡcontent: It was significantly lower in sham-operation group and captopril group than in model group (130.2±30.2),(137.6±39.5),(196.7±48.6) μg/g, t=4.026, P < 0.01 . 6 Comparison of ALD level: It was significantly lower in sham operation group and captopril group than in model group (170.6±51.6), (202.5±64.2), (339.3±115.4) μg/L, t=4.623, P < 0.01 . CONCLUSION: 1 Captopril decreased myocardial collagen typeⅠand type Ⅲ and mRNA expression in rats with pressure overload, suggesting its effect in reversing left ventricular remodeling. 2 The reversing effect of captopril on left ventricular remodeling might be related to decreasing circulating or local AngⅡ level, plasma ANF and serum aldosterone as well as affecting the expression of collagen typeⅠand type Ⅲ mRNA.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Hu Wan-ying",
                "org": "Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai , China"
            },
            {
                "name": "Wang Yan-jun",
                "org": "Postdoctor Institute of Hebei Medical University, Shijiazhuang , Hebei Province, ChinaCai Hui, Doctor, Professor, Chief physician, Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Guo Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Hu Bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            },
            {
                "name": "Yao Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing , Jiangsu Province, China"
            }
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2005
    },
    "bIjPbMuu": {
        "id": "bIjPbMuu",
        "title": "Guidance Line Identification Algorithm for AGV in Complex Environment",
        "abstract": "In order to quickly and accurately identify the guidance line in complex environment,a line recognition algorithm based on prior knowledge was proposed.Images were divided into several regions by field range and line characteristic.Both means of full image and region were used to make adaptive threshold of each region.Scanning mode was decided by information of previous image,then noises were filtered and intermediate points were acquired.An improved Hough transformation with search angle limitation and nonuniform sampling was applied to localize guidance line.Finally cross ratio theorem was used to calibrate the parameters.The experimental result showed the method was characterized by robustness and real-time,the average computing time was about 90 ms for each image.",
        "keywords": [
            "Automated guided vehicle",
            "Hough transformation",
            "Image processing",
            "Road recognition"
        ],
        "authors": [
            {
                "name": "Cai Jinhui",
                "org": "1.College of Metrology and Measurement Engineering,China Jiliang University,Hangzhou ,China ;2.Department of Control Science and Engineering,Zhejiang University,Hangzhou ,China "
            },
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhang Guangxin",
                "org": "2.Department of Control Science and Engineering,Zhejiang University,Hangzhou ,China "
            },
            {
                "name": "Zhou Zekui",
                "org": "2.Department of Control Science and Engineering,Zhejiang University,Hangzhou ,China "
            }
        ],
        "venue": "Transactions of the Chinese Society for Agricultural Machinery",
        "year": 2011
    },
    "dqa47oG2": {
        "id": "dqa47oG2",
        "title": "P04.19. T’ai chi as exercise among middle age and elderly Chinese in urban China",
        "abstract": "",
        "keywords": [
            "Physical Activity",
            " Health Study",
            " Healthy Behavior",
            " Predominant Form",
            " Chronic Medical Condition"
        ],
        "authors": [
            {
                "name": "gurjeet s birdee",
                "org": "Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "hui cai",
                "org": "Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "yang xiang",
                "org": "Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "g yang",
                "org": "Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "h li",
                "org": "Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "wei zheng",
                "org": "Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "xiaoou shu",
                "org": "Vanderbilt University Medical Center,Nashville,USA"
            }
        ],
        "venue": "BMC Complementary and Alternative Medicine",
        "year": 2012
    },
    "LXhHM9QJ": {
        "id": "LXhHM9QJ",
        "title": "Connection Conservatory",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2009
    },
    "Y6w18S0C": {
        "id": "Y6w18S0C",
        "title": "Modifiable Lifestyle Factors and Triple-negative Breast Cancer Survival: A Population-based Prospective Study.",
        "abstract": "Background: Very little is known about the effect of modifiable lifestyle factors on outcomes of triple-negative breast cancer. We examined this association in a population-based prospective cohort study of patients with triple-negative breast cancer. Methods: A total of 518 women with confirmed triple-negative breast cancer, recruited by the Shanghai Breast Cancer Survival Study, completed 6-, 18-, 36-, and 60-month postdiagnosis surveys. We applied Cox proportional hazard models to evaluate the associations. Results: The mean age at diagnosis was 53.4 (standard deviation = 10.6) years old. After a median follow-up of 9.1 years (range: 0.6-11.8), 128 deaths and 112 recurrences were documented. Exercise during the first 60 months postdiagnosis was inversely associated with total mortality and recurrence/disease-specific mortality with adjusted hazard ratios (HRs) of 0.67 (95% confidence interval [CI] = 0.46, 0.96) and 0.58 (95% CI = 0.39, 0.86), respectively. Women with higher exercise-metabolic equivalent scores (7.6 metabolic equivalent-hours/week) and longer duration of exercise (2.5 hours/week) had lower risk of total and recurrence/disease-specific mortality than did nonexercisers. Compared with nontea drinkers, survival was better among women who were regular tea drinkers during the first 60 months for all cause (HR = 0.57, 95% CI = 0.34, 0.93) and recurrence/disease-specific mortality (HR = 0.54, 95% CI = 0.31, 0.96). There was no dose-response pattern for tea consumption. No interactions were observed for body mass index, menopausal status, and comorbidity. Conclusions: These findings show that postdiagnosis exercise and tea intake were associated with improved survival among women with triple-negative breast cancer.",
        "keywords": "",
        "authors": [
            {
                "name": "Ping-Ping Bao",
                "org": "Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Gen-Ming Zhao",
                "org": "Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Peng Peng",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            }
        ],
        "venue": "EPIDEMIOLOGY",
        "year": 2015
    },
    "fQ8DGkR2": {
        "id": "fQ8DGkR2",
        "title": "Dietary glycemic load and risk of colorectal cancer in Chinese women.",
        "abstract": "Background: Mixed results have been reported in recent epidemiologic studies in Western populations that have investigated the hypothesis that high glycemic load may increase the risk of colorectal cancer. This association has not been prospectively evaluated in other populations. Objective: We examined the association of overall glycemic index and glycemic load with colorectal cancer risk in a prospective cohort of Chinese women. Design: A total of 73,061 women aged 40-70 y and free of cancer at enrollment were included in this analysis. Usual dietary intake was assessed at baseline (1997-2000) and reassessed during the first follow-up (2000-2002) through in-person interviews by using a validated food-frequency questionnaire. Results: During an average follow-up of 9.1 y, 475 incident colorectal cancer cases were identified. Glycemic load was not associated with colorectal cancer risk (P for trend = 0.84). The multivariable hazard ratio for the highest compared with the lowest quintile of glycemic load was 0.94 (95% CI: 0.71, 1.24). Similar results were also observed for associations with dietary glycemic index and total carbohydrate intake, and results did not vary by excluding individuals with a history of diabetes from the analysis. Conclusion: This prospective study, conducted in a population with a high intake of carbohydrates, provides no evidence that a high-glycemic index diet or high glycemic load is associated with an increased risk of colorectal cancer. Am J Clin Nutr 2011;93:101-7.",
        "keywords": [
            "china",
            "cohort studies",
            "risk",
            "prospective studies"
        ],
        "authors": [
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med,Div Epidemiol, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF CLINICAL NUTRITION",
        "year": 2011
    },
    "PpYs1xYp": {
        "id": "PpYs1xYp",
        "title": "Study on the significance and the changes of Raf-1 and Ki67 expression before and after neoadjuvant chemotherapy in breast cancer",
        "abstract": "Objective To investigate the expression of Raf-1 and Ki67 in breast cancer correlation levels with clinical pathological characteristics,and study on their changes before and after neoadjuvant chemotherapy. Methods Using immunohistochemical method( SP method) to detect the positive expression of Raf-1 and Ki67 in breast cancer tissue of 186 cases,including tissue samples of 68 cases before and after neoadjuvant chemotherapy. Results The expressions of Raf-1 and Ki67 in breast cancer were significantly correlated with clinical stages and lymph node metastasis and TNM stage( P < 0. 001); After neoadjuvant chemotherapy in the positive expressions of Raf-1 and Ki67 than before neoadjuvant chemotherapy were decreased,the difference was statistically significant( P < 0. 001); Raf-1 and Ki67 changes in the expression of the value before and after neoadjuvant chemotherapy were significantly associated with chemotherapy( P < 0. 001),the better the effect of neoadjuvant chemotherapy,Raf-1 protein and Ki67 decreased more obviously. Conclusions There was close relationship between the occurrence and development and positive expression of Raf-1 and Ki67 in breast cancer. Effects of neoadjuvant chemotherapy on expression of Raf-1 and Ki67,after neoadjuvant chemotherapy to detect expression of Raf-1 and Ki67,provide guidance for the follow-up treatment and prognosis.",
        "keywords": [
            "Neoadjuvant chemotherapy",
            "Breast neoplasms",
            "Ki67",
            "Raf-1"
        ],
        "authors": [
            {
                "name": "XU Yang",
                "org": ""
            },
            {
                "name": "WANG Li-ning",
                "org": ""
            },
            {
                "name": "LI Han",
                "org": ""
            },
            {
                "name": "WANG Jue",
                "org": ""
            },
            {
                "name": "CAI Hui",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Clinicians(Electronic Edition)",
        "year": 2013
    },
    "r30pevIQ": {
        "id": "r30pevIQ",
        "title": "Predictors and Variability of Repeat Measurements of Urinary Phenols and Parabens in a Cohort of Shanghai Women and Men",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "butian ji",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "stephanie m engel",
                "org": ""
            },
            {
                "name": "mary s wolff",
                "org": ""
            },
            {
                "name": "nathaniel rothman",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "charles e matthews",
                "org": ""
            },
            {
                "name": "antonia m calafat",
                "org": ""
            },
            {
                "name": "linda m liao",
                "org": ""
            },
            {
                "name": "jaya m satagopan",
                "org": ""
            },
            {
                "name": "lawrence s engel",
                "org": ""
            },
            {
                "name": "jessie p buckley",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "wongho chow",
                "org": ""
            }
        ],
        "venue": "Environmental Health Perspectives",
        "year": 2014
    },
    "XJktPe2j": {
        "id": "XJktPe2j",
        "title": "Effect analysis of Chinese herbal drugs on primary osteoporosis",
        "abstract": "Objective It is to make a system assessment on the therapeutic effects and adverse reaction of Chinese herbal drugs(CHD) on the treatment of primary osteoporosis(POP).Methods Cochrane system assessment was used,clinical trials relevanted to CHD on the treatment of POP in the databases of CNKI were retrieved,and the methodological quality of the included trials were evaluated.Meta-analyses were conducted with the RevMan 5.0 software.Nine studies and 850 cases of POP were included,and divided into CHD group with 476 cases and control group with 374 cases. Results Compared with the control group,the relative risk of the CHD group was 1.84,the 95% CI was from 1.45 to 2.33,P<0.001.Conclusion CHD therapy has a better therapeutic effect on POP and little adverse reaction.",
        "keywords": [
            "Meta-analysis",
            "primary osteoporosis",
            "Chinese herbal drugs"
        ],
        "authors": [
            {
                "name": "Guo Junhao",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Yang Luxin",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2009
    },
    "BkOEZi4C": {
        "id": "BkOEZi4C",
        "title": "A plum blossom stands for 50 years:Commemorating Small-Sword Society's birth",
        "abstract": "OUTLINE / Dance drama Small-Sword Society was an outstanding Chinese original dance drama.It was a hit during the early years of the founding of new China; it toured abroad and was made into a film. It was on 11 January 1960 that Chairman Mao Zedong and Premier Zhou Enlai attended a performance.To commemorate the 50~(th) anniversary of that special day, Shanghai Opera House invited the production team and performers for a get-together.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "uF13MZoz": {
        "id": "uF13MZoz",
        "title": "Expression of dectin-1 and β2-defensin in rat with Pneumocystis carinii pneumonia",
        "abstract": "Objective To study the expression of dectin-1 and β2-defensin in rats with Pneumocystis carinii pneumonia(PCP),and to explore the influence of dexamethasone on the expression of dectin-1 and β2-defensin and its relationship with progression of PCP.Methods Fifty-three rats were divided into four groups: normal control,P.carinii(Pc) stimulation,PCP model and recovered PCP model.PCP rats were induced with dexamethasone in this study,and Pc cysts were detected by Grocoti's methenamine-silver nitrate(GMS) staining.Real-time PCR and Western blot were used to detect the expression of dectin-1 and β2-defensin in the lung tissues,and HE staining for pathological examination of the lung tissues.Results The expressions of dectin-1 and β2-defensin were significantly higher in the Pc stimulation group than that of the normal group(P<0.05),and in the Pc stimulation group and recovered PCP group than that of PCP model group(P<0.05).The burden of Pc cysts in recovered PCP group was less than that in the PCP group,while the inflammation was similar between them.Conclusions During the Pc infection,the expression of dectin-1 and β2-defensin in the lung of immunocompetent rats is strikingly increased,which may play an important role in the defense against the Pc invasion.Dexamethasone inhibites the expression of dectin-1 and β2-defensin in the rat lung,and it may be one of mechanisms of PCP development induced by P.carinii.",
        "keywords": [
            "Dexamethasone",
            "Pneumocystis carinii",
            "Dectin-1",
            "β2-defensin",
            "Rat model"
        ],
        "authors": [
            {
                "name": "ZHENG Yu-qiang",
                "org": "Laboratory Medicine,Childrens Hospital of Chongqing University of Medical Sciences,Ministry of Education Key Laboratory of Child Development,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperration Center for Child Development and Disorders,Chongqing ,China"
            },
            {
                "name": "LIU Ai-bo",
                "org": "Laboratory Medicine,Childrens Hospital of Chongqing University of Medical Sciences,Ministry of Education Key Laboratory of Child Development,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperration Center for Child Development and Disorders,Chongqing ,China"
            },
            {
                "name": "PU Yu",
                "org": "Laboratory Medicine,Childrens Hospital of Chongqing University of Medical Sciences,Ministry of Education Key Laboratory of Child Development,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperration Center for Child Development and Disorders,Chongqing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathogen Biology,Chongqing University of Medical Sciences,Chongqing "
            },
            {
                "name": "YE Bin",
                "org": "Department of Pathogen Biology,Chongqing University of Medical Sciences,Chongqing "
            }
        ],
        "venue": "Acta Laboratorium Animalis Scientia Sinica",
        "year": 2013
    },
    "iT7QRm1L": {
        "id": "iT7QRm1L",
        "title": "Synthesis and evaluation of potential Nπ and Nσ metal chelation sites within the β-hydroxy-l-histidine subunit of bleomycin A2: Functional characterization of imidazole Nπ metal complexation",
        "abstract": "The synthesis and evaluation of 4 and 5, fully functionalized deglycobleomycin A(2) (2) analogues incorporating an oxazole and a pyrrole in place of the beta-hydroxy-L-histidine imidazole, are detailed, The oxazole agent is only capable of N-pi metal complexation through a form related to the N-1-H imidazole tautomer of bleomycin A(2) (1) while the pyrrole agent may potentially mimic the N-sigma metal complexation capabilities of the imidazole N-3-H tautomer. Metal complexes (Fe-II, Fe-III) of 4 and 5 were found to cleave duplex DNA in the presence of O-2 (Fe-II) or H2O2 (Fe-III). The oxazole agent 4 which is incapable of N-sigma metal chelation was found to behave analogous to, albeit slightly less effectively than, deglycobleomycin A(2) resulting in the characteristic 5'-GC/5'-GT sequence selective cleavage of duplex DNA directly confirming that imidazole/oxazole N-pi metal chelation is sufficient for functional reactivity. Importantly, the effective substitution of the oxazole O-1 for the histidine N-1 further illustrates that this group does not require deprotonation upon metal complexation, oxygen activation, or the ensuing oxidation reactions, that the functional bleomycin A(2) tautomer is the imidazole N-1-H tautomer, and that the imidazole N-1-H functionality is not contributing to the polynucleotide recognition through H-bonding to the phosphate backbone or nucleotide bases. In contrast, the pyrrole agent 5 which is incapable of N-pi metal chelation, but possesses the capabilities of functioning as a N-sigma metal donor was also found to cleave duplex DNA, but does so in a nonsequence selective fashion with a significantly reduced efficiency and a diminished double to single strand cleavage ratio both only slightly above that of background iron itself. These observations are analogous to those made with 3 which lacks the imidazole altogether and further support the observations that N-pi coordination, not N-sigma coordination, of the imidazole is required for the functional activity of bleomycin A(2).",
        "keywords": [],
        "authors": [
            {
                "name": "Dale L. Boger",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Timothy M. Ramsey",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1996
    },
    "H7l7Bo8K": {
        "id": "H7l7Bo8K",
        "title": "Unusual Pressure Response of Vibrational Modes in Anisotropic TaS3",
        "abstract": "We report on the unique vibrational properties of 2D anisotropic orthorhombic tantalum trisulfide (o-TaS3) measured through angle-resolved Raman spectroscopy and high-pressure diamond anvil cell studies. Our broad-spectrum Raman measurements identify optical and low-frequency shear modes in pseudo-1D o-TaS3 for the first time, and introduce their polarization resolved Raman responses to understand atomic vibrations for these modes. Results show that, unlike other anisotropic systems, only the S∥ mode at 54 cm–1 can be utilized to identify the crystalline orientation of TaS3. More notably, high-pressure Raman measurements reveal previously unknown four distinct types of responses to applied pressure, including positive, negative, and nonmonotonic dω/dP behaviors which are found to be closely linked to atomic vibrations for involving these modes. Our results also reveal that the material approaches an isotropic limit under applied pressure, evidenced by a significant reduction in the degree of anisotropy. O...",
        "keywords": "",
        "authors": [
            {
                "name": "Kedi Wu",
                "org": "Arizona State University"
            },
            {
                "name": "Bin Chen",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State University"
            },
            {
                "name": "Mark Blei",
                "org": "Arizona State University"
            },
            {
                "name": "Juliana Bennett",
                "org": "Arizona State University"
            },
            {
                "name": "Shengxue Yang",
                "org": "Beihang University"
            },
            {
                "name": "David Wright",
                "org": "Arizona State University"
            },
            {
                "name": "Yuxia Shen",
                "org": "Arizona State University"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State University"
            }
        ],
        "venue": "Journal of Physical Chemistry C",
        "year": 2017
    },
    "Sj39LhHI": {
        "id": "Sj39LhHI",
        "title": "Imaging of pure spin-valley diffusion current in WS-WSe heterostructures.",
        "abstract": "Transition metal dichalcogenide (TMDC) materials are promising for spintronic and valleytronic applications because valley-polarized excitations can be generated and manipulated with circularly polarized photons and the valley and spin degrees of freedom are locked by strong spin-orbital interactions. In this study we demonstrate efficient generation of a pure and locked spin-valley diffusion current in tungsten disulfide (WS)-tungsten diselenide (WSe) heterostructures without any driving electric field. We imaged the propagation of valley current in real time and space by pump-probe spectroscopy. The valley current in the heterostructures can live for more than 20 microseconds and propagate over 20 micrometers; both the lifetime and the diffusion length can be controlled through electrostatic gating. The high-efficiency and electric-field-free generation of a locked spin-valley current in TMDC heterostructures holds promise for applications in spin and valley devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Chenhao Jin",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Jonghwan Kim",
                "org": "Department of Materials Science and Engineering, Pohang University of Science and Technology, Pohang 790-784, Korea."
            },
            {
                "name": "M Iqbal Bakti Utama",
                "org": "Department of Materials Science and Engineering, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Emma C Regan",
                "org": "Graduate Group in Applied Science and Technology, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Hans Kleemann",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA."
            },
            {
                "name": "Yuxia Shen",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA."
            },
            {
                "name": "Matthew James Shinner",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Arjun Sengupta",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, CA 94720, USA."
            },
            {
                "name": "Kenji Watanabe",
                "org": "National Institute for Materials Science, 1-1 Namiki, Tsukuba, 305-0044, Japan."
            },
            {
                "name": "Takashi Taniguchi",
                "org": "National Institute for Materials Science, 1-1 Namiki, Tsukuba, 305-0044, Japan."
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA."
            },
            {
                "name": "Alex Zettl",
                "org": "Kavli Energy NanoSciences Institute at the University of California at Berkeley and Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA."
            },
            {
                "name": "Feng Wang",
                "org": "Kavli Energy NanoSciences Institute at the University of California at Berkeley and Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA."
            }
        ],
        "venue": "Science (New York, N.Y.)",
        "year": 2018
    },
    "5fPw8Xlc": {
        "id": "5fPw8Xlc",
        "title": "Transplantation of controlled-release gliocytes-derived neurotrophic factors and bone marrow mesenchymal stem cells-derived neuron-like cells for remylination of the corticospinal tract of the injured spinal cord in macaca mulatta",
        "abstract": "BACKGROUND: Remyelination disturbance is one of factors inducing functional handicap following spinal cord injury. OBJECTIVE: To investigate the synergism of transplantation of controlled-release biomaterial of glial cell lined-derived neurotrophic factor on the myelin repair when transplantation with neuron-like cells derived from bone marrow mesenchymal stem cells (BMSCs) after spinal cord injury of macaca mulatta. DESIGN, TIME AND SETTING: The randomized, controlled, animal study was performed at the Department of Pathology, Chuiyangliu Hospital, Beijing, China from May to July 2008. MATERIALS: Twelve spinal cord paraffin specimen of macaca mulatta were collected by professor Deng research team in Sun Yat-sen University from January 2004 to January 2005 as a retrospective experimental subjects. There were 3 groups, namely combined transplantation group, cell transplantation group and model control group, with 4 cases in each group. METHODS: Macaca mulatta BMSCs were isolated by the density gradient method. At passages 5-8, BMSCs were induced to differentiate into neurons. Severe acute spinal cord injury models were established in each group. In the combined transplantation group, BMSCs were preinduced using tanshinone for 1.5 hours at 10 days, and BMSCs-induced neuron-like cells (3.0×10 6/kg) were collected, mixed with methoxyl poly(ethylene glycol)-poly(lactic acid) copolymer containing 2 μg gliocytes-derived neurotrophic factors, added with 200 μL phosphate buffer saline, and then made into suspension. The suspension was infused into 5 sites of the spinal cord injured regions. Samples in the cell transplantation group received phosphate buffer saline containing BMSCs-derived neurons-like cells induced by an equal volume of tanshinone. Samples in the model control group were subjected to the same volume of phosphate buffer saline. MAIN OUTCOME MEASURES: Results of hematoxylin-eosin staining and solochrome cyanine staining in corticospinal tract myelin sheath; mean absorbance of the myelin sheath. RESULTS: Remyelination was better in range and density of the repair on corticospinal tract myelin sheath in the combined transplantation group compared with the cell transplantation group based on solochrome cyanine staining, but not hematoxylin-eosin staining. Corticospinal tract structure was severely destroyed, without myelin sheath structure in the model control group. Image analysis results revealed that the mean absorbance was similar in the corticospinal tract myelin sheath between the combined transplantation group and cell transplantation group (t =1.725, P > 0.05). CONCLUSION: Controlled-release gliocytes-derived neurotrophic factors can enhance the repairing outcome of BMSCs-derived neuron-like cells on corticospinal tract myelin sheath of injured spinal cord of macaca mulatta.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Liu Xiao-gang",
                "org": "Chuiyangliu Hospital (Beijing Minimal Invasion Hospital)(Beijing Minimally Invasive Hospital,Chuiyangliu Hospital (Beijing Minimal Invasion Hospital),Peking Minimally Invasive Hospital),Beijing,China"
            },
            {
                "name": "Deng Yu-bin",
                "org": "Sun Yat-Sen University(Zhongshan University,Sun Yat-Sen University,Sun Yat-sen University),Guangzhou,China"
            },
            {
                "name": "Hui Cai",
                "org": "Chuiyangliu Hospital (Beijing Minimal Invasion Hospital)(Beijing Minimally Invasive Hospital,Chuiyangliu Hospital (Beijing Minimal Invasion Hospital),Peking Minimally Invasive Hospital),Beijing,China"
            },
            {
                "name": "Ma Yu-lin",
                "org": "Chuiyangliu Hospital (Beijing Minimal Invasion Hospital)(Beijing Minimally Invasive Hospital,Chuiyangliu Hospital (Beijing Minimal Invasion Hospital),Peking Minimally Invasive Hospital),Beijing,China"
            },
            {
                "name": "Xu Hong-lan",
                "org": "Chuiyangliu Hospital (Beijing Minimal Invasion Hospital)(Beijing Minimally Invasive Hospital,Chuiyangliu Hospital (Beijing Minimal Invasion Hospital),Peking Minimally Invasive Hospital),Beijing,China"
            }
        ],
        "venue": "Journal of Clinical Rehabilitative Tissue Engineering Research",
        "year": 2009
    },
    "SvOzWabP": {
        "id": "SvOzWabP",
        "title": "Neuropsychiatric lupus:An update",
        "abstract": "This article discusses the status quo of the researches on neuropsychiatric lupus,including its pathophysiological mechanism,clinical manifestation,diagnosis,treatment and prognosis.Cerebrospinal fluid examination,electroencephalography and brain imaging could improve the sensitivity of the diagnosis of neuropsychiatric lupus.Aggressive immunosuppressive agents,high-dose corticosteroids and anticoagulants remain the key to the therapy.However,future researches should focus on the control of long-term relapse and the improvement of the quality of life.",
        "keywords": [
            "Neuropsychiatric lupus",
            "Systemic lupus erythematosus",
            "Clinical classification"
        ],
        "authors": [
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "FU Xiao-dong",
                "org": "Institute of Integrated Traditional Chinese and Western Medicine,Huashan Hospital,Shanghai ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WANG Wen-jian",
                "org": "Institute of Integrated Traditional Chinese and Western Medicine,Huashan Hospital,Shanghai ,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "0qk7sd8O": {
        "id": "0qk7sd8O",
        "title": "Effects of panax notoginseng saponins on the proliferation of cyclic citrullinated peptide antigen special T cell in rheumatoid arthritis",
        "abstract": "Objective To observe effects of panax notoginseng saponins(PNS) on the proliferation of cyclic citrullinated peptide antigen special T(CCP/AST) cell in rheumatoid arthritis in vitro.Methods Peripheral blood lymphocytes(PBLs) of 24 RA patients were cultured in vitro.All patients were divided into five groups.In blank control group,PBLs were cultured and not interfered by drug.In CCP group,PBLs were interfered by CCP(degree of enrichment 20 μg/mL).In methotrexate(MTX)control group,PBLs were interfered by CCP and MTX(each degree of enrichment 20 μg/mL).In low PNS group,PBLs were interfered by CCP and PNS(respective degree of enrichment 20 μg/mL and 10 μg/mL).In high PNS group,PBLs were interfered by CCP and PNS(each degree of enrichment 20 μg/mL).After cultured respectively in vitro for 72 h,T cell proliferation were detected applying CCK-8.Results Compared with that of blank control group(0.49±0.06),the peripheral blood T cell proliferation of CCP group(0.70±0.08) obviously increases,and difference has statistical significance(P<0.01).Compared with that of CCP group,T cell proliferation of low PNS group and high PNS group both had been suppressed(0.57±0.06,0.47±0.06 vs 0.70±0.08),and difference has statistical significance respectively(P<0.01).Compared with that of low PNS group,T cell proliferation of high PNS group had been more suppressed,and difference has statistical significance(P<0.01).Conclusion PNS has depression effects on CCP/AST cell proliferation of RA and depression extent may be correlated with dose,which may play an important role in the treatment of RA.",
        "keywords": [
            "Arthritis",
            "T lymphocytes",
            "Cyclic citrullinated peptide",
            "Cell proliferation",
            "Sanchinoside",
            "rheumatoid"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            }
        ],
        "venue": "Shanxi Medical Journal",
        "year": 2011
    },
    "oqA7a2dj": {
        "id": "oqA7a2dj",
        "title": "Red meat and poultry intakes and risk of total and cause-specific mortality: results from cohort studies of Chinese adults in Shanghai.",
        "abstract": "Most previous studies of meat intake and total or cause-specific mortality were conducted in North America, whereas studies in other areas have been limited and reported inconsistent results. This study investigated the association of red meat or poultry intake with risk of total and cause-specific mortality, including cancer and cardiovascular disease (CVD), in two large population-based prospective cohort studies of 134,290 Chinese adult women and men in Shanghai. Meat intakes were assessed through validated food frequency questionnaires administered in person at baseline. Vital status and dates and causes of deaths were ascertained through annual linkage to the Shanghai Vital Statistics Registry and Shanghai Cancer Registry databases and home visits every 2-3 years. Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of death associated with quintiles of meat intake. During 803,265 person-years of follow up for women and 334,281 person-years of follow up for men, a total of 4,210 deaths in women and 2,733 deaths in men accrued. The median intakes of red meat were 43 g/day among women and 54 g/day among men, and pork constituted at least 95% of total meat intake for both women and men. Red meat intake was associated with increased total mortality among men, but not among women; the HR (95% CI) comparing the highest with the lowest quintiles were 1.18 (1.02-1.35) and 0.92 (0.82-1.03), respectively. This sex difference was statistically significant (P = 0.01). Red meat intake was associated with increased risk of ischemic heart disease mortality (HR = 1.41, 95% CI = 1.05-1.89) and with decreased risk of hemorrhagic stroke mortality (HR = 0.62, 95% CI = 0.45-0.87). There were suggestive inverse associations of poultry intake with risk of total and all-CVD mortality among men, but not among women. Further investigations are needed to elucidate the sex-specific associations between red meat intake and mortality.",
        "keywords": [
            "chemistry",
            "biology",
            "medicine",
            "engineering",
            "physics"
        ],
        "authors": [
            {
                "name": "Yumie Takata",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Jing Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University(Vanderbilt University),Nashville,United States"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "MAKEwh2J": {
        "id": "MAKEwh2J",
        "title": "Protective effect of tanshinone IIA against myocardial hypertrophy in rats with pressure overload",
        "abstract": "AIM: To observe the changes of RhoA and Rock1 expressions in rat myocardial tissues with pressure overload and to explore the protective effects of tanshinone ⅡA(Tan IIA) against myocardial hypertrophy.METHODS: Thirty-two Sprague Dawley(SD) rats induced by abdominal aorta constriction preparation were randomly divided into four groups(each n=8): model group(P<0.01),Tan ⅡA of low-dose group [L-Tan ⅡA group,10 mg/(kg·day)],Tan ⅡA of high-dose group [H-Tan IIA group,20 mg/(kg·day)],positive captopril group [captopril group,100 mg/(kg·day)] and age-matched SD sham-operated group(n=8) as control.The model of pressure overload-induced myocardial fibrosis was successfully established after 4 weeks of operation.After 4 weeks of Tan ⅡA treatment,heart mass indexes were estimated concurrently with evaluation of myocardial histology as well as myocardial hydroxyproline content by ELISA and immunohistochemistry staining and Western blot for myocardial RhoA and Rock1 content.RESULTS: Compared with those in sham group,heart mass indexes,myocardial hydroxyproline content and myocardial RhoA and Rock1 content were increased in the model group(P<0.01).Compared with those in model group,heart mass indexes,myocardial hydroxyproline content and myocardial RhoA and Rock1 content were decreased in the L-Tan ⅡA group(P<0.05),whereas these indexes were decreased significantly in the H-Tan ⅡA group(P<0.01).CONCLUSIONS: Expressions of RhoA and Rock1 protein significantly increase in pressure overload rat myocardium,indicating that RhoA/Rock signaling pathways are involved in pressure overload in rat cardiac hypertrophy and occurrence and development of cardiac hypertrophy in rats with pressure overload.Tan ⅡA can alleviate cardiac hypertrophy possibly by downregulation of the expression of RhoA/Rock signaling pathways.",
        "keywords": [
            "tanshinone ⅡA",
            "RhoA/Rock signaling pathway",
            "pressure overload",
            "rat",
            "myocardial hypertrophy"
        ],
        "authors": [
            {
                "name": "CHANG Wen-jing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,Jangsu,China"
            }
        ],
        "venue": "Chinese Heart Journal",
        "year": 2013
    },
    "zflnE5rW": {
        "id": "zflnE5rW",
        "title": "Impact of newly diagnosed breast cancer on quality of life among Chinese women.",
        "abstract": "Being diagnosed with breast cancer is a very stressful event that has a profound impact on multiple aspects of a patient's daily life. Little is known about the quality of life (QOL) of Chinese women with newly diagnosed breast cancer.The authors evaluated QOL in 2,236 Chinese women with newly diagnosed breast cancer who were recruited into the Shanghai Breast Cancer Survival Study between April 1, 2002 and March 31, 2004. Patients' QOL was assessed after cancer diagnosis (median time 6.4 months; range 3.6-11.1 months) by using the General Quality of Life Inventory. Multiple linear regression models were used to analyze the associations of QOL outcomes with medical and socio-demographic factors.Patients showed significantly worse overall QOL and perceived health status than healthy women, reflected mainly by lower QOL scores in physical and psychological well-being domains. Completion of radiotherapy, ever use of tamoxifen, being underweight, having an increased number of chronic diseases, and low household income were significantly associated with lower overall QOL scores after adjusting for other factors. Age at diagnosis was inversely associated with physical well-being, positively associated with material well-being, and had minimal influence on overall QOL. Stage of disease, chemotherapy, and education were only associated with certain domains, but had no influence on overall QOL. Estrogen receptor/progesterone receptor status and type of surgery or immunotherapy did not appear to be associated with QOL.The findings of the present study provide important information on QOL and their correlates among Chinese women with newly diagnosed breast cancer and are helpful in developing treatment strategies accordingly.",
        "keywords": [
            "breast cancer æ quality of life æ chinese women",
            "breast cancer",
            "estrogen receptor",
            "psychological well being",
            "progesterone receptor",
            "multiple linear regression",
            "quality of life"
        ],
        "authors": [
            {
                "name": "Wei Lu",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Yong Cui",
                "org": "Vanderbilt University Medical Center, Medical Center East, Suite 6000, 1215 21st Avenue South Department of Medicine, Center for Health Services Research Nashville TN 37232-8300 USA"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University Medical Center, Medical Center East, Suite 6000, 1215 21st Avenue South Department of Medicine, Center for Health Services Research Nashville TN 37232-8300 USA"
            },
            {
                "name": "Qiong Li",
                "org": "Vanderbilt University Medical Center, Medical Center East, Suite 6000, 1215 21st Avenue South Department of Medicine, Center for Health Services Research Nashville TN 37232-8300 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University Medical Center, Medical Center East, Suite 6000, 1215 21st Avenue South Department of Medicine, Center for Health Services Research Nashville TN 37232-8300 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt University Medical Center, Medical Center East, Suite 6000, 1215 21st Avenue South Department of Medicine, Center for Health Services Research Nashville TN 37232-8300 USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2007
    },
    "y9KEyins": {
        "id": "y9KEyins",
        "title": "Circulating C-reactive protein and colorectal cancer risk: a report from the Shanghai Men's Health Study.",
        "abstract": "Chronic inflammation has been implicated in the pathogenesis of colorectal cancer. The objective of this study was to evaluate the association of prediagnostic circulating levels of C-reactive protein (CRP), a biomarker of systemic inflammation, with subsequent development of colorectal cancer. Prediagnostic plasma CRP levels were examined among 288 colorectal cancer cases and 576 individually-matched controls nested within the Shanghai Men's Health Study (2002-06), a population-based cohort study of 61 482 Chinese men. The association between CRP levels and colorectal cancer risk was investigated. Baseline plasma CRP levels were 53% higher among men who subsequently developed colorectal cancer than among those who remained free of the disease (1.15 versus 0.75 mu g/ml; P < 0.001). Multivariate analyses showed a dose-dependent relationship between CRP and colorectal cancer risk (P trend = 0.003); men in the highest tertile (CRP > 1.19 mu g/ml) had 1.88-fold (95% confidence interval (CI): 1.24-2.86) increased odds of developing colorectal cancer compared with men in the lowest tertile (CRP < 0.45 mu g/ml). The association was only significant for colon cancer, when cancer site was considered, and was predominantly seen for cases diagnosed within 4 years of blood collection; adjusted odds ratios for the highest versus the lowest tertiles were 3.28 (95% CI: 1.28-8.37), 3.68 (95% CI: 1.62-8.38) and 1.05 (95% CI: 0.56-1.97), respectively, for cases diagnosed < 2, 2-4 and > 4 years after blood collection. The findings from our study suggest that circulating CRP level is positively associated with colorectal cancer risk in Chinese men, and this association, at least in part, is explained by inflammation-related cancerous or precancerous processes.",
        "keywords": [
            "case control studies",
            "risk"
        ],
        "authors": [
            {
                "name": "Jie Wu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, Dept Epidemiol,Renji Hosp, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, Dept Epidemiol,Renji Hosp, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Sch Med, Shanghai Canc Inst, Dept Epidemiol,Renji Hosp, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "CARCINOGENESIS",
        "year": 2013
    },
    "U6OJfvFJ": {
        "id": "U6OJfvFJ",
        "title": "<Emphasis Type=\"Italic\">MTHFR</Emphasis> genotypes and breast cancer survival after surgery and chemotherapy: a report from the Shanghai Breast Cancer Study",
        "abstract": "Methylenetetrahydrofolate reductase (MTHFR) regulates the intracellular folates pool for DNA synthesis and methylation. Sequence variations in MTHFR (nucleotides 677 (C→T) and 1298 (A→C)) result in allozymes with decreased activity. The 677TT genotype is associated with increased toxicity of methotrexate and increased clinical response to 5-fluorouracil in treatment of cancers including breast cancer. We evaluated MTHFR genotypes and breast cancer survival in a cohort of 1067 Chinese women diagnosed with breast cancer between 1996 and 1998 who received surgery and chemotherapy. Life table method was used to calculate 5-year survival rates. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) after adjusting for potential confounding factors. Median follow-up time was 5.2 years; 5-year survival was 84.6%. Sixty-six percent carried a 677T allele and 31% carried a 1298 C allele. We found that overall 5-year breast cancer survival did not differ significantly across all genotypes (85.3% for 677 CC and 83.8% for 677TT; 83.8% for 1298 AA and 79.1% for 1298 CC). However, carrying the 677T allele was associated with non-significant increased risk of death for subjects with late stage disease (stages III–IV) (HR=1.80, 95% CI: 0.79–4.14 for TT vs. CC, p for trend=0.15), particularly among those who had survived past the second year (HR=2.97, 95% CI: 1.10–7.98, p for trend=0.04). The A1298C genotypes were not significantly associated with risk of death. This study suggests that the MTHFR C677T polymorphisms may affect long-term survival from advanced breast cancer.",
        "keywords": [
            "breast neoplasms",
            " gene",
            " MTHFR",
            " survival"
        ],
        "authors": [
            {
                "name": "Martha J. Shrubsole",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            },
            {
                "name": "Zhi Xian Ruan",
                "org": "Department of Epidemiology,Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            },
            {
                "name": "Qi Niu",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology,Shanghai Cancer Institute,Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine, Division of Internal Medicine, Vanderbilt School of Medicine,Vanderbilt University,Nashville"
            }
        ],
        "venue": "Breast Cancer Research and Treatment",
        "year": 2005
    },
    "ZZw93mPB": {
        "id": "ZZw93mPB",
        "title": "Effects of Lysophosphatidic Acid on the Production of ET, NO and TGF β_1 in Myocardial Fibroblasts in Neonate Rats",
        "abstract": "Objective To investigate the effects of lysophosphatidic acid on the production of ET, NO and TGFβ1 in cardiac fibroblasts (CFs) in neonate rats. Methods CFs were isolated by trypsin digestion method, the changes of ET, NO and TGFβ1 production from CFs were examined by radio immunoassay, nitrate reductase-dependent assay and by enzyme linked immunosorbent assay(ELISA), respectively. Results LPA(1×10 -9-1×10 -6mol/L)decreased ET and TGFβ1 synthesis in a concentration-dependent manner( P<0.05), but showed no significant changes to NO production(P<0.05). Conclusion These results showed that LPA can decrease the production of ET, TGFβ1 and influence the balance of these factors. LPA may inhibit myocardial fibrosis by modulating these cytokines.",
        "keywords": [
            "Endothelin",
            "Cardiac fibroblasts",
            "Nitric oxide",
            "TGFβ1",
            "Lysophosphatidic acid"
        ],
        "authors": [
            {
                "name": "ZHAO Zhi-ming",
                "org": ". Dept. of Combined Western and Chinese Medicine, General Hospital of Nanjing Military Command, Nanjing , China"
            },
            {
                "name": "CAI Hui",
                "org": ". Dept. of Combined Western and Chinese Medicine, General Hospital of Nanjing Military Command, Nanjing , China"
            },
            {
                "name": "GUO Jun-hao",
                "org": ". Dept. of Combined Western and Chinese Medicine, General Hospital of Nanjing Military Command, Nanjing , China"
            }
        ],
        "venue": "Journal of Chinese Microcirculation",
        "year": 2006
    },
    "efmg2p3k": {
        "id": "efmg2p3k",
        "title": "On Division and Combination of TCM and WM",
        "abstract": "It expounds the common ground of early development of TCM and WM,the different development models of them,as well as future developing combination trend of them,from combination to division,then to differentiation unification;meanwhile,it points out the combination of them is the necessary rule of development,the necessary trend of medical development and the happiness of human being health.",
        "keywords": [
            "modern medicine",
            "TCM",
            "combination of TCM"
        ],
        "authors": [
            {
                "name": "Cai Jiayu",
                "org": " General Nanjing Hospital of Military Zone of P.L.A.%%#%%#"
            },
            {
                "name": "Cai Hui",
                "org": " General Nanjing Hospital of Military Zone of P.L.A.%%#%%#"
            },
            {
                "name": "Zhao Lingjie",
                "org": " General Nanjing Hospital of Military Zone of P.L.A.%%#%%#"
            }
        ],
        "venue": "Journal of Zhejiang University of Traditional Chinese Medicine",
        "year": 2010
    },
    "ZpU9RxEB": {
        "id": "ZpU9RxEB",
        "title": "Effect of metoprolol on plasma TNF-α in rat model with isoproterenol-induced congestive heart failure",
        "abstract": "Objective To explore the effect of metoprolol on plasma tumour necrosis factor-α(TNF-α) in rats with congestive heart failure(CHF).Methods 80 male SD rats were randomly allocated to the isoproterenol(ISO)-induced heart failure group(n=70) receiving a subcutaneous injection of ISO(170 mg per kilogram of body weight) twice and the healthy normal group(n=10) receiving a subcutaneous injection of 0.25 ml of normal saline twice.At the 6th week,the left ventricular ejection fractions(LVEF) were measured by echocardiogram,the remaining rats,with a LVEF≤45%,were randomly divided into two groups: heart failure control group(n=13),metoprolol group(n=14,8 mg/kg-1· d-1,i.g.,).At the 18th week,the hemodynamic parameters were detected,including HR,LVEDP,LVSP and ±dp/dtmax;LVWI was measured after LV morphopathological examination.TNF-α in plasma was examined by radioimmunoassay.Results ①Compared with the normal group,the heart function significantly deteriorated;VWI,LVWI and the plasma TNF-α significantly increased(P<0.01) in the heart failure control group.②Compared with the heart failure control group,the heart function markedly improved,and the VWI,LVWI and the plasma TNF-α decreased significantly(P<0.05) in the metoprolol group,with an improved ventricular remodeling.Conclusion Metoprolol can inhibit the plasma TNF-α,improve heart function and reverse ventricular remodeling with CHF.Its effect might be involved in the inhibition of the expression of plasma TNF-α in hear failure rats.",
        "keywords": [
            "TNF-α",
            "isoproterenol",
            "ventricular remodeling",
            "metoprolol",
            "congestive heart failure",
            "rats"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "GUO Han",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Jiayu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "GUO Junhao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Acta Academiae Medicinae Xuzhou",
        "year": 2010
    },
    "tpmgziXi": {
        "id": "tpmgziXi",
        "title": "The changes of bone density and OPG/RANKL protein in adjuvant arthritis rats",
        "abstract": "Objective To investigate the bone mineral density and the expression of OPG and RANKL protein in ankle of rats with adjuvant arthritis.Methods SD rats were established adjuvant arthritis model and separated into normal group,model 1 group,and model 2 group.Arthritis index was observed in each model group at different time of 7 day,14 day,21 day and 28 day after modeling.Rats in model 1 group were sacrificed at the 21st day,the ones in the normal group and model 2 group were at the 28th day.The bone mineral density of the whole right side of the tibia and about 1cm from the distal tibia called interest region were detected.At the same time,the expression of OPG/RANKL protein of bilateral ankle synovial membranes was inspected by Western-blotting.Results The arthritis indexes of each time point of model 1 and model 2 groups had difference compared with the normal group(P<0.01).The bone mineral density of interest region of model 1 group were lower than that in normal group(P<0.01).The interest region of model 2 group significantly reduced compared with those in the normal and model 1 groups(P<0.01).The overall right tibia bone mineral density had no significant difference.The expression of OPG protein in model 1 and model 2 groups was significantly different compared with the normal group(P<0.01).RANKL protein of model 2 group,not model 1 group,was significantly different compared with normal group(P<0.01).Conclusion Adjuvant arthritis rats lost distal tibial bone 21 days after the modeling,and aggravated in 28 days.While the overall tibia bone mineral density had no difference.The expression of rat synovial OPG protein decreased at the 21st day and 28th day after modeling.At the 28th day after modeling,the expression of rat synovial RANKL protein was higher than the normal.",
        "keywords": [
            "Osteoprotegerin",
            "Nuclear factor-kappa B receptor activation factor ligand",
            "Arthritis",
            "Bone density",
            "experimental"
        ],
        "authors": [
            {
                "name": "SHANG Wei",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu ,China"
            }
        ],
        "venue": "Shanxi Medical Journal",
        "year": 2013
    },
    "ybojjZTY": {
        "id": "ybojjZTY",
        "title": "Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors",
        "abstract": "The synthesis and evaluation of 1-4 as potential inhibitors of GAR Tfase and AICAR Tfase are detailed. (C) 1998 Elsevier Science Ltd. All rights reserved.",
        "keywords": [],
        "authors": [
            {
                "name": "Dale L Boger",
                "org": "Department of Chemistry, Scripps Research Institute, La Jolla, California 92037, USA."
            },
            {
                "name": "Monica J Kochanny",
                "org": "Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA"
            },
            {
                "name": "Diane Wyatt",
                "org": "Department of Biochemistry, University of Kansas, Lawrence, Kansas 66045, USA"
            },
            {
                "name": "Paul A Kitos",
                "org": "Department of Biochemistry, University of Kansas, Lawrence, Kansas 66045, USA"
            },
            {
                "name": "M.S Warren",
                "org": "Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA"
            },
            {
                "name": "J Ramcharan",
                "org": "Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA"
            },
            {
                "name": "Lata T Gooljarsingh",
                "org": "Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA"
            },
            {
                "name": "Stephen J Benkovic",
                "org": "Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, USA"
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1998
    },
    "ONRZ8R9i": {
        "id": "ONRZ8R9i",
        "title": "Adaptive multi-scale AMSS operator for quality detection of silks",
        "abstract": "In order to de-noise the silk images corrupted by various noises, a new improved filter based on affine morphological scale space (AMSS) equation was proposed. In this new operator both the adaptive idea and scale space were fused into partial differential equations. Scale parameters were changed adaptively according to the presence or absence of noise in image which was detected by directional gradient operators with four templates. A new evaluating criterion was constructed to test the performance of the improved AMSS operators. Two parameters based on mean square error and minimum absolute error could be acquired to evaluate the effect of keeping edge information and the ability of smoothing noise. Experimental results illustrate that this improved operator can efficiently keep edge information, and the de-noising performance is more effective than other methods for the image with multi-noise.",
        "keywords": [
            "directional gradient operator",
            "edge information",
            "improved operator",
            "improved amss operator",
            "quality detection",
            "new operator",
            "de-noising performance",
            "new improved filter",
            "scale parameter",
            "scale space",
            "affine morphological scale space",
            "partial differential equation",
            "image processing",
            "mean square error",
            "noise reduction"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "National Key Laboratory of Industrial Control Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China"
            },
            {
                "name": "Jinhui Cai",
                "org": "College of Metrology Technology and Engineering, China Jiliang University, Hangzhou, People's Republic of China"
            },
            {
                "name": "Guangxin Zhang",
                "org": "National Key Laboratory of Industrial Control Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China"
            },
            {
                "name": "Zekui Zhou",
                "org": "National Key Laboratory of Industrial Control Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou, People's Republic of China"
            }
        ],
        "venue": "Int. J. Comput. Math.",
        "year": 2009
    },
    "fwUDS5ov": {
        "id": "fwUDS5ov",
        "title": "The context of new urbanism and its enlightenment",
        "abstract": "This article mainly analyzes the deep-seated social and cultural backgrounds of the \"New Urbanism\",as well as it's theoretical origin.Though this,at the same time compared to the status quo of China's urban development,the author explores that as a new urban development trend of the later 1990s——the \"New Urbanism\",what it can be learned for our country's urban development.",
        "keywords": [
            "New Urbanism",
            "urbanization",
            "reference"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ""
            },
            {
                "name": "HE Xu-dan",
                "org": ""
            }
        ],
        "venue": "Urban Problems",
        "year": 2010
    },
    "nAz5Zgkk": {
        "id": "nAz5Zgkk",
        "title": "Effect of Curcumin on Angiogenesis in Synovium of Adjuvant Arthritis rats",
        "abstract": "Objective To explore the possible role of curcumin in rheumatoid arthritis (RA) by investigating angiogengsis,expression of vascular endothelial growth factor(VEGF) and vascular endothelial growth factor receptor-2 (VEGFR-2) in synovium of adjuvant arthritis rats. The expression of VEGF in blood serum was also detected. Methods 14 SD rats were divided into normal control group,model group,curcumin group and methotrexat group,modelling with Complete Freund's adjuvant. The rats of curcumin group were treated with 50 mg·kg-1·d-1 curcumin intraperitoneal injection continuously for 14 days and rats of methotrexat group were treated with 0.5 mg·kg-1·3d-1 methotrexat intraperitoneal injection for 5 times. The effects of treatment were monitored by measurement of arthritis index number(AI) at d9,d23. The expressions of VEGF in serum was detected by ELISA. Investigate synovium microvessels density and the expression of vascular endothelial growth factor/ vascular endothelial growth factor receptor-2 by immunohistochemical test. Results The arthritis index number of the rats injected CFA increased. Compared with normal group,the difference was significant(P<0.01) at d9. At d23,the AI of curcumin group and methotrexat group had significant difference compared with model group(P<0.01). The results of ELISA showed that curcumin and methotrexat can attenuate the degree of VEGF in serum(P<0.01). Immunohistochemical test showed that the expression of MVD,VEGF,VEGFR-2 had significant difference compared curcumin group and methotrexat group with model group(P<0.01),the difference between curcumin group and methotrexat group was not significant(P>0.05). Conclusion Curcumin can attenuate the degree of VEGF in serum,inhibit the expression VEGF and VEGFR-2 in the synovium and reduce MVD. It might be one of the machanism of curcuim in curing rheumatoid arthritis.",
        "keywords": [
            "Vascular endothelial growth factor",
            "Curcumin",
            "Arthritis",
            "Angiogenesis"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu, China"
            },
            {
                "name": "SHANG Wei",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu, China"
            },
            {
                "name": "GUO Jun-Hao",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu, China"
            },
            {
                "name": "ZHENG Zhao-Ling",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu, China"
            },
            {
                "name": "ZHAO Zhi-Ming",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu, China"
            }
        ],
        "venue": "Journal of Chinese Microcirculation",
        "year": 2009
    },
    "27HDJk2v": {
        "id": "27HDJk2v",
        "title": "Acupuncture on the high fat rat aortic endothelial bcl-2 and bax influence",
        "abstract": "Objective: To investigate the high-fat diet on SD rat aortic endothelial apoptosis,and the impact of the role of acupuncture.Methods: 17 SD rats were just weaning high fat diet for 12 weeks of serum NO and MPO,were randomly divided into model group(n=8) and the acupuncture group(9 rats),serum after 4 weeksNO,MPO and aortic NO,SOD,MDA,bax,bcl-2,and let normal diet control group(9 rats).RESULTS: MPO serum and aortic MDA,bax were significantly higher in serum and aortic NO,aortic SOD and bcl-2 was significantly lower than the control group;acupuncture serum MPO and aortic MDA,bax waslower serum and aortic NO,aortic SOD and bcl-2 significantly increased.Conclusion: The high fat diet increased the SD rat aortic endothelial oxidative stress,resulting in increased apoptosis of aortic endothelial;Acupuncture can reduce the high fat diet rat aortic endothelial oxidative stress and improve the withered aortic endothelialdeath.",
        "keywords": [
            "acupuncture",
            "bcl-2",
            "oxidative stress action",
            "bax",
            "fat"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "Yuan Aihong",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Guiding Journal of Traditional Chinese Medicine and Pharmacy",
        "year": 2010
    },
    "l6Irk4Rc": {
        "id": "l6Irk4Rc",
        "title": "Theory and application of path-reconstruction operator",
        "abstract": "In order to efficiently filter noises by length and orientation characters of objects,a binary path-reconstruction operator was brought forward based on morphological reconstruction.In order to construct a path-reconstruction operator,firstly adjacencies were defined for marker image,and connected components were labeled for mask image.Secondly some connected components were selectively reconstructed according to the δ-path length of corresponding regions in marker image.Then the proposed operator was extended to grey-path reconstruction with threshold decomposition.It was shown by image enhancing results and diagrams that the path-reconstruction operator could effectively utilize grad information,length and orientation attributes of object.",
        "keywords": [
            "Image segmentation",
            "Morphological filter",
            "Path opening",
            "Reconstruction operator"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Dibo Hou",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "TANG Xiao-fen",
                "org": "National Laboratory of Industrial Control Technology,Dept.of Control Science & Engineering,Zhejiang Univ.,Hangzhou ,China"
            },
            {
                "name": "Guangxin Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "National Laboratory of Industrial Control Technology,Dept.of Control Science & Engineering,Zhejiang Univ.,Hangzhou ,China"
            }
        ],
        "venue": "Journal of Optoelectronics.Laser",
        "year": 2009
    },
    "gpkzS5Nx": {
        "id": "gpkzS5Nx",
        "title": "Network frame optimization method for defending multi-DC commutation failure",
        "abstract": "In a multi-infeed receiving-end power grid, the commutation failure in multiple HVDC systems will seriously threatens the safe and stable operation of the power system when serious AC fault occurs. Firstly, based on the concepts of electrical distance, this paper proposes a weakness evaluation index to find out the buses whose short circuit faults may cause commutation failure in multiple HVDC systems. Secondly, an index for finding out the key branches between a target bus and a point of common coupling (PCC) is put forward. Then, combined with MMC-HVDC transmission technology, a network frame optimization method for defending multi-infeed DC commutation failure is presented. Finally, the correctness and validity of the proposed method are verified by simulation in a modified New England 39-bus system using the simulation software PSS/E.",
        "keywords": "",
        "authors": [
            {
                "name": "Wanchun Qi",
                "org": "State Grid Jiangsu Electric Power Co., Ltd. Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Electric Power Co., Ltd. Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Wenjia Zhang",
                "org": "State Grid Jiangsu Electric Power Co., Ltd. Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Guoteng Wang",
                "org": "Zhejiang University, College of Electrical Engineering, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Zhejiang University, College of Electrical Engineering, Hangzhou, China"
            },
            {
                "name": "Xiaomei Yang",
                "org": "State Grid Jiangsu Electric Power Co.,Ltd.,Nanjing,China"
            }
        ],
        "venue": "ieee pes asia pacific power and energy engineering conference",
        "year": 2019
    },
    "U19VamEE": {
        "id": "U19VamEE",
        "title": "Change of myocardial cell apoptosis in rats with congestive heart failure induced by ISO",
        "abstract": "Objective To establish the animal model of congestive heart failure(CHF)in rats induced by isoproterenol ( ISO ) and to investigate the changes of myocardial cell apoptosis. Methods 60 male Sprague-Dawley rats were randomly divided into the ISO-induced chronic heart failure group(ISO group,n = 50)receiving subcutaneous injections of 170mg ISO per-kilogram twice,and the healthy control group ( CON group,n = 10)receiving subcutaneous injections of 0. 25ml normal saline twice. At 18th week,the hemodynamic parameters were detected,including heart rate left ventricular end diastolic pressure,LV systolic pressure,and LVWI was measured after LV morphopathological examination. the DNA fragmentation was detected by agarose gel electrophoresis method,and the levels of Bax,cleaved caspase-9 and cleaved caspase-3 were detected by Western Blot method. Results As compared with the CON group,the HR,LVEDP,LVWI,and the DNA fragmentation,the levels of Bcl-2,Bax,cleaved caspase-9 and cleaved caspase-3 in the myocardial were significantly increased. But LVSP,± dp/dtmax and Bcl-2 were significantly decreased in CHF group( P < 0. 01). Conclusion Increased myocardial cell apoptosis level was shown as a marker in isoproterenol-induction rat model of CHF.",
        "keywords": [
            "Sprague-Dawley rats",
            "cell apoptosis",
            "heart",
            "muscle cell",
            "heart failure",
            "ISO"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al. Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA,Nanjing ,China"
            },
            {
                "name": "GUO Han",
                "org": ",et al. Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": ",et al. Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA,Nanjing ,China"
            }
        ],
        "venue": "Hebei Medical Journal",
        "year": 2010
    },
    "zMpJnQio": {
        "id": "zMpJnQio",
        "title": "Abstract 4285: Intra-individual variation in circulating miRNA expression levels in human plasma samples",
        "abstract": "Circulating miRNAs as possible non-invasive biomarkers for disease risk assessment and cancer early diagnosis has attracted increasing interest. Little information, however, is available regarding the intra-individual variation of circulating miRNA levels. We measured miRNA expression in repeated plasma samples that were collected 6 to 12 months apart from 53 healthy individuals participating in a sub-study nested in the Shanghai Women9s and Shanghai Men9s Health Studies. Total RNA, including miRNA, was isolated from plasma using Qiagen9s miRNeasy Serum/Plasma Kit. Three synthetic spike-in RNA oligos (osa-miR414, cel-miR248, and ath-miR159a) were added to control for variances in the starting material and the efficiency of RNA extraction. NanoString9s Human v2 miRNA Expression Assay, which includes CodeSets of probes specific for 800 common human miRNAs, was used for the miRNA assays. The derived miRNA counts were first corrected by subtracting the background counts and then were normalized by using the average count from three spike-in oligos and  the top fifty miRNAs that gave most significant hybridization signals. The intra-individual variation was evaluated by an intra-class correlation coefficient (ICC). A total of 185 miRNAs were detected in at least 10% of samples. The detectable rate varied for each miRNA, with 69 and 44 miRNAs being detected in 50% and 75% of samples, respectively. The median ICC was 0.46 for all of the 185 detectable miRNAs. Among them, 41% (75 miRNAs) had an ICC ≥0.5, and 42 miRNAs had an ICC ≥0.6. The ICC is higher for miRNAs with higher expression levels and higher detection rates, when compared to their counterparts with lower expression or detection rates. In summary, we found that 185 miRNAs were expressed in at least 10% of plasma samples, and 69 miRNAs in 50% of samples from healthy Chinese men and women, and that 75 of these miRNAs had an ICC ≥0.5. These results suggest that common circulating miRNAs can serve as reliable biomarkers for epidemiological and clinical research.   Citation Format:  Jie Wu, Hui Cai, Yong-Bing Xiang, Charles Matthews, Fei Ye, Wei Zheng, Qiuyin Cai, Xiao-Ou Shu. Intra-individual variation in circulating miRNA expression levels in human plasma samples. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4285.",
        "keywords": "",
        "authors": [
            {
                "name": "Jie Wu",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Cancer Institute, Shanghai, China;"
            },
            {
                "name": "Charles E. Matthews",
                "org": "National Cancer Institute, Bethesda, MD."
            },
            {
                "name": "Fei Ye",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University, Nashville, TN;"
            }
        ],
        "venue": "Cancer Research",
        "year": 2016
    },
    "TyANocKJ": {
        "id": "TyANocKJ",
        "title": "The effect of MTX on the weight of immune organs in rats with adjuvant arthritis",
        "abstract": "Objective To investigate the immunopharmacodynamics of methotrexate(MTX) and its effect on the variations of the weights of the immune organs(thymus and spleen) in rat models with adjuvant arthritis(AA).Methods 30 SD rats were randomly divided according to body weight into normal control group,model group and MTX group.Model group and MTX group were induced by Freund′s complete adjuvant(FCA) to establish rat models.Normal control group and model group were intraperitoneally administered 5% Glucose Injection 2 ml/d for 14 days and MTX group was administered MTX 0.3 mg·kg-1·d-1(dissolved in 5% Glucose Injection 2ml),i.p.,for 14 days until they were sacrificed the next day after the final administration and their thymus and spleen were obtained and weighed on an electronic balance to calculate the ponderal index.Results The thymic weight and the ponderal index in MTX group were lower than the parameters in model group,and the differences were considered statistically significant(P<0.05);while the differences of spleen weight between groups were insignificant(P>0.05).Conclusion MTX can reduce thymic weight and the ponderal index in rat model with AA,hence contributing to cellular immunity.",
        "keywords": [
            "cellular immunity",
            "adjuvant arthritis",
            "MTX"
        ],
        "authors": [
            {
                "name": "ZHENG Zhaoling",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Acta Academiae Medicinae Xuzhou",
        "year": 2009
    },
    "G6eYyNFu": {
        "id": "G6eYyNFu",
        "title": "Genetic polymorphisms in the human growth hormone-1 gene (GH1) and the risk of breast carcinoma.",
        "abstract": "BACKGROUND. In addition to possessing many physiologic functions, human growth hormone-1 (GH1) has been shown in recent in vitro and in vivo experiments to induce malignant disease, including breast carcinoma. The authors investigated the association of breast carcinoma with genetic polymorphisms in the GH1 gene in the Shanghai Breast Cancer Study. METHODS. Included in the current investigation were 1193 women with breast carcinoma (case patients) and 1310 healthy women from the same community (control patients) who completed in-person interviews and provided blood samples. Genetic polymorphisms in the proximal promoter region (nucleotide [m] -162 to nt +148 relative to the transcription start site of the GH1 gene) were searched and confirmed by resequencing DNA samples from 43 study participants. A novel polymorphism, a transition from adenine to guanine at or 69 (A69G), was identified. Samples from all participants were genotyped with TaqMan 5' nuclease assays for five common single-nucleotide polymorphisms (SNPs)-four in the proximal region (A-75G, G-57T, A-6G, and A69G) and one in intron 4 (T1169A). RESULTS. The frequencies of occurrence for the minor alleles in these polymorphic sites were 0.04, 0.60, 0.24, 0.03, and 0.34, respectively, in the control group; these frequencies were comparable to those observed in the case group. After adjusting for potential confounding factors, none of the SNPs investigated in this study showed a statistically significant association with breast carcinoma risk. This null association was found for both younger women (age < 45 years) and older women (age greater than or equal to 45 years). GH1 gene haplotypes were assessed using SNP data and were analyzed in relation to breast carcinoma risk. Again, none of the haplotypes were associated with breast carcinoma risk. CONCLUSIONS. The results of the current study suggest that genetic polymorphisms in the proximal promoter region and in the fourth intron of the GH1 gene are unrelated to breast carcinoma risk in Chinese women. (C) 2004 American Cancer Society.",
        "keywords": [
            "GH1 gene polymorphism",
            "breast carcinoma",
            "susceptibility",
            "Chinese women"
        ],
        "authors": [
            {
                "name": "Zefang Ren",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Jia-Rong Cheng",
                "org": ""
            },
            {
                "name": "Wan-Qing Wen",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "CANCER",
        "year": 2004
    },
    "rclQg7um": {
        "id": "rclQg7um",
        "title": "The influence of total flavonoids of epimedium on the activity of serum superoxide dismutase in hyperlipemia rats",
        "abstract": "Objective To investigate the influence of total flavonoids of epimedium(TFE) on the activity of serum superoxide dismutase in hyperlipemia rats. Methods Thirty-five male SD rats were randomly divided into the high-fat diet group(n=26) and full diet group(n=9).Rats in high-fat diet group were randomly subdivided into hyperlipemia group(n=8),high dose TFE group(n=9) and low dose TFE group(n=9) after 12 weeks with high-fat diet.Lavage with TFE of 200 mg/day 100 mg/day were given to rats in high dose TFE and low dose TFE groups,respectively,for 4 weeks.The activity of serum superoxide dismutase was measured. Results Significant increase of TG,TC and LDL were observed in hyperlipemia group,comparing with those in full diet group(P<0.01).Compared with that in controls,the activity of serum superoxide dismutase was significantly elevated in TFE intervention groups. Conclusion TFE protects endothelial cells against oxidative stress by elevating the activity of serum superoxide dismutase in hyperlipemia rats.",
        "keywords": [
            "hyperlipemia",
            "total flavonoids of epimedium",
            "superoxide dismutase"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ".Department of integrated traditional and western medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".Department of integrated traditional and western medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": ".Department of integrated traditional and western medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ".Department of integrated traditional and western medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Department of integrated traditional and western medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Guangdong Medical Journal",
        "year": 2011
    },
    "XGuDPx2X": {
        "id": "XGuDPx2X",
        "title": "Soy Food Intake and Breast Cancer Survival",
        "abstract": "Context Soy foods are rich in isoflavones, a major group of phytoestrogens that have been hypothesized to reduce the risk of breast cancer. However, the estrogen-like effect of isoflavones and the potential interaction between isoflavones and tamoxifen have led to concern about soy food consumption among breast cancer patients. Objective To evaluate the association of soy food intake after diagnosis of breast cancer with total mortality and cancer recurrence. Design, Setting, and Participants The Shanghai Breast Cancer Survival Study, a large, population-based cohort study of 5042 female breast cancer survivors in China. Women aged 20 to 75 years with diagnoses between March 2002 and April 2006 were recruited and followed up through June 2009. Information on cancer diagnosis and treatment, lifestyle exposures after cancer diagnosis, and disease progression was collected at approximately 6 months after cancer diagnosis and was reassessed at 3 follow-up interviews conducted at 18, 36, and 60 months after diagnosis. Annual record linkage with the Shanghai Vital Statistics Registry database was carried out to obtain survival information for participants who were lost to follow-up. Medical charts were reviewed to verify disease and treatment information. Main Outcome Measures Total mortality and breast cancer recurrence or breast cancer-related deaths. Cox regression analysis was carried out with adjustment for known clinical predictors and other lifestyle factors. Soy food intake was treated as a time-dependent variable. Results During the median follow-up of 3.9 years (range, 0.5-6.2 years), 444 deaths and 534 recurrences or breast cancer-related deaths were documented in 5033 surgically treated breast cancer patients. Soy food intake, as measured by either soy protein or soy isoflavone intake, was inversely associated with mortality and recurrence. The hazard ratio associated with the highest quartile of soy protein intake was 0.71 (95% confidence interval [CI], 0.54-0.92) for total mortality and 0.68 (95% CI, 0.54-0.87) for recurrence compared with the lowest quartile of intake. The multivariate-adjusted 4-year mortality rates were 10.3% and 7.4%, and the 4-year recurrence rates were 11.2% and 8.0%, respectively, for women in the lowest and highest quartiles of soy protein intake. The inverse association was evident among women with either estrogen receptor-positive or-negative breast cancer and was present in both users and nonusers of tamoxifen. Conclusion Among women with breast cancer, soy food consumption was significantly associated with decreased risk of death and recurrence. JAMA. 2009; 302(22): 2437-2443",
        "keywords": [
            "breast cancer"
        ],
        "authors": [
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            },
            {
                "name": "Zhi Chen",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Inst Prevent Med, Shanghai, Peoples R China"
            }
        ],
        "venue": "JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION",
        "year": 2009
    },
    "8sCCpoO2": {
        "id": "8sCCpoO2",
        "title": "Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese women.",
        "abstract": "Cumulative evidence suggests that insulin-like growth factors (IGF) play an important role in the etiology of breast cancer. The IGF binding proteins regulate the action of IGFs, and >90% of circulating IGFs are bound to IGFBP-3. We evaluated the associations of five (A-202C, G227C, C3804G, 5606InsA, and C5827T) genetic polymorphisms in the IGFBP3 gene with breast cancer risk and the blood IGFBP-3 protein level in a population-based, case-control study conducted among Chinese women in Shanghai. Genomic DNA samples from 1,193 incident breast cancer patients and 1,310 community controls were genotyped for IGFBP3 polymorphisms. Blood IGFBP-3 levels were determined for 390 controls. A 30% to 60% elevated risk of breast cancer was found to be associated with homozygosity for the variant allele in polymorphisms A-202C, G227C, 5606InsA, and C5827T. Carrying the variant allele in C3804G was also associated with an increased risk. About 13.5% of cases and 9.7% of controls had one or more of the above risk genotypes, resulting in odds ratio [OR; 95% confidence interval (95% CI)] of 1.4 (1.0-1.9). The ORs (95% CIs) were 1.3 (1.0-1.8) and 1.7 (1.1-2.5) for women with one to two and three to five risk genotypes, respectively (P for trend < 0.01). Four common haplotypes for the IGFBP3 gene were identified. Compared with the haplotype containing only the wild-type allele in the five loci, the haplotype with the variant allele in all sites was associated with an elevated risk of breast cancer (OR 1.4, 95% CI 1.0-1.9), particularly among younger women (OR 2.3, 95% CI 1.3-3.9). With the exception of C3804G, in which no homozygote was identified, the level of circulating IGFBP-3 was reduced in a dose-response manner with an increasing number of variant alleles in each of the other four polymorphic sites (P for trend < 0.05). These results indicated that IGFBP3 polymorphisms may be associated with the level of blood IGFBP-3 protein and an increased risk of breast cancer.",
        "keywords": [],
        "authors": [
            {
                "name": "Zefang Ren",
                "org": "Department of Medicine, Vanderbilt University, Nashville, TN, USA."
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Chun Li",
                "org": ""
            },
            {
                "name": "Herbert Yu",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology",
        "year": 2004
    },
    "fqUgs3Hv": {
        "id": "fqUgs3Hv",
        "title": "2-aminopyrimidine modulators of the histamine H4 receptor",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "frank chavez",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "anne e fitzgerald",
                "org": ""
            },
            {
                "name": "jing liu",
                "org": ""
            },
            {
                "name": "neelakandha s mani",
                "org": ""
            },
            {
                "name": "danielle k neff",
                "org": ""
            },
            {
                "name": "michele c rizzolio",
                "org": ""
            },
            {
                "name": "brad m savall",
                "org": ""
            },
            {
                "name": "deborah m smith",
                "org": ""
            },
            {
                "name": "jennifer d venable",
                "org": ""
            },
            {
                "name": "jianmei wei",
                "org": ""
            },
            {
                "name": "ronald l wolin",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "nuDnxx6h": {
        "id": "nuDnxx6h",
        "title": "The Eye as a Target Organ for Stem Cell Therapy",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "mark a fields",
                "org": "medical university of south carolina"
            },
            {
                "name": "john hwang",
                "org": "university of southern california"
            },
            {
                "name": "jie gong",
                "org": "medical university of south carolina"
            },
            {
                "name": "hui cai",
                "org": "columbia university"
            },
            {
                "name": "lucian v del priore",
                "org": "medical university of south carolina"
            }
        ],
        "venue": "",
        "year": 2013
    },
    "TZPmZrG8": {
        "id": "TZPmZrG8",
        "title": "The effects of Controlled release GDNF to the differentiation of neural precursor cells derived from bone marrow mesenchymal stem cells marked by BrdU in injured spinal cord",
        "abstract": "Objective To investigate the value of BMSCs tracer method by BrdU in vivo,and the effects of controlled release GDNF to the differentiation of transplanted cells.Methods Two groups of paraffin specimens about spinal cord injury experimental study of macaca mulatta were collected,one group treated by neural precursor cells derived from BMSCs and controlled release GDNF,another group treated only by cells,each group including 4 cases.Immune double staining was applied,including BrdU and Nestin,BrdU and NF,BrdU and GFAP,to show transplanted cells trace and differentiation.Results BrdU and NF or GFAP double positive cells could be observed in both paraffin specimens groups,whereas,Nestin was negative.More BrdU positive cells(P = 0.10) and much stronger NF expressing level(P < 0.05) could be found in combined transplantation group.Besides,more survival neurons also could be found(P < 0.05).Conclusion BrdU marking method for tracing stem cells in vivo is a kind of effective method.Controlled release of GDNF can enhance the survival of the transplanted cells and native neurons,and enhance transplanted cells differentiation potential to neurons,so as to be more effective to promote nerve function rehabilitation.",
        "keywords": [
            "Mesenchymal stem cells",
            "Spinal cord",
            "BrdU"
        ],
        "authors": [
            {
                "name": "LIU Xiao-gang",
                "org": "Department of Pathology,Chui Yang-liu hospital of Beijing,Beijing ,China"
            },
            {
                "name": "DENG Yu-bin",
                "org": "Department of Pathology,Chui Yang-liu hospital of Beijing,Beijing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathology,Chui Yang-liu hospital of Beijing,Beijing ,China"
            }
        ],
        "venue": "Journal of Apoplexy and Nervous Diseases",
        "year": 2013
    },
    "SxdQjU0v": {
        "id": "SxdQjU0v",
        "title": "Tunable electronic structure in gallium chalcogenide van der Waals compounds",
        "abstract": "  Transition metal monochalcogenides comprise a class of two-dimensional materials with electronic band gaps that are highly sensitive to material thickness and chemical composition. Here, we explore the tunability of the electronic excitation spectrum in GaSe using angle-resolved photoemission spectroscopy. The electronic structure of the material is modified by $\\textit{in-situ}$ potassium deposition as well as by forming GaS$_{x}$Se$_{1-x}$ alloy compounds. We find that potassium decouples the top-most tetra-layer of the GaSe unit cell, leading to a substantial change of the dispersion around the valence band maximum (VBM). The observed band dispersion of a single tetralayer is consistent with a transition from the direct gap character of the bulk to the indirect gap character expected for monolayer GaSe. Upon alloying with sulfur, we observe a phase transition from AB to $\\text{AA}^{\\prime}$ stacking. Alloying also results in a rigid energy shift of the VBM towards higher binding energies which correlates with a blue shift in the luminescence. The increase of the band gap upon sulfur alloying does not appear to change the dispersion or character of the VBM appreciably, implying that it is possible to engineer the gap of these materials while maintaining their salient electronic properties. ",
        "keywords": "",
        "authors": [
            {
                "name": "Brian Shevitski",
                "org": ""
            },
            {
                "name": "Søren Ulstrup",
                "org": ""
            },
            {
                "name": "Roland J. Koch",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Sefaattin Tongay",
                "org": ""
            },
            {
                "name": "Luca Moreschini",
                "org": ""
            },
            {
                "name": "Chris Jozwiak",
                "org": ""
            },
            {
                "name": "Aaron Bostwick",
                "org": ""
            },
            {
                "name": "Alex Zettl",
                "org": ""
            },
            {
                "name": "Eli Rotenberg",
                "org": ""
            },
            {
                "name": "Shaul Aloni",
                "org": ""
            }
        ],
        "venue": "Physical Review B",
        "year": 2019
    },
    "xlh0Ehed": {
        "id": "xlh0Ehed",
        "title": "Abstract 13422: Associations of Circulating Trimethylamine-n-Oxide (TMAO) With Dietary Intakes and Cardiometabolic Biomarkers: Results From the TMAO Pooling Project",
        "abstract": "Background: Trimethylamine-N-oxide (TMAO), a diet-derived, gut microbial-host co-metabolite, has been linked to cardiovascular disease (CVD). Population-based, multi-ethnic studies on the associati...",
        "keywords": "",
        "authors": [
            {
                "name": "Jae Jeong Yang",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "David M Herrington",
                "org": ""
            },
            {
                "name": "Steven C Moore",
                "org": ""
            },
            {
                "name": "Katie A Meyer",
                "org": ""
            },
            {
                "name": "Jennifer Ose",
                "org": ""
            },
            {
                "name": "Cristina Menni",
                "org": ""
            },
            {
                "name": "Nicholette D Palmer",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Sei Harada",
                "org": ""
            },
            {
                "name": "Huilian Zhu",
                "org": ""
            },
            {
                "name": "Demetrius Albanes",
                "org": ""
            },
            {
                "name": "Thomas J Wang",
                "org": ""
            },
            {
                "name": "Cornelia M Ulrich",
                "org": ""
            },
            {
                "name": "Myriam Fornage",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Charles E Mattews",
                "org": ""
            },
            {
                "name": "Fang-Chi Hsu",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Robert E Gerszten",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Danxia Yu",
                "org": ""
            }
        ],
        "venue": "Circulation",
        "year": 2019
    },
    "WJcGp7X1": {
        "id": "WJcGp7X1",
        "title": "Influence of pioglitazone on PPARγ-NF-kB expression of aorta in hyperlipidemia rat",
        "abstract": "Objective To explore the effects of pioglitazone on the expressions of PPARγ and NF-kB of aorta in hyperlipemic rats.Methods 26 male SD rats were randomly divided into two groups: the high-fat diet group(control group,n=17) and full diet group(n=9).high-fat diet group were fed high-fat diet(HF) for 12 weeks,then serum lipid level was measured in the all rats,and when the hyperlipidemia model was estimated,the high-fat diet group rats were randomly divided into two groups: the model group,high-fat diet with Pioglitazone group.By intragastric administration,Pioglitazone group was given pioglitazone(0.6mg/ml)for four weeks,and control group and model group were given with tales doses of distilled water for four weeks.After 4 weeks' treatment,serum lipid level was measured in the rats.the aorta was taken for pathologic analysis.Serum levels of NO was detected,the level of NOS of aorta,the expression of PPARγ and NF-kB were detected by western bolt.Results After 12 weeks of feeding,the hyperlipidemia model was estimated.After 4 weeks,treatment,As Compared with model group,serum levels of TG,TC decreased significantly(P<0.01).The level of NO,cNOS in Pioglitazone group were significantly increased(P<0.01).The protein expression of PPARγ was significantly increased(P<0.05),but the protein expression of NF-kB was significantly inhibited.Conclusion Pioglitazone can effectively prevent vascular endothelium from impairment by restoring NO,cNOS,PPARγ concentration and down-regulale NF-kB expression in these rats.",
        "keywords": [
            "pioglitazone",
            "NF-kB",
            "hyperlipemic",
            "PPAR",
            "rat"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al.Nanjing Military General Hospital,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Jia-yu",
                "org": ",et al.Nanjing Military General Hospital,Nanjing,Jiangsu ,China"
            },
            {
                "name": "XU Yu-shun",
                "org": ",et al.Nanjing Military General Hospital,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Sichuan Medical Journal",
        "year": 2011
    },
    "F20tJ84g": {
        "id": "F20tJ84g",
        "title": "Abnormal band bowing effects in phase instability crossover region of GaSe 1-x Te x nanomaterials",
        "abstract": "Akin to the enormous number of discoveries made through traditional semiconductor alloys, alloying selected 2D semiconductors enables engineering of their electronic structure for a wide range of new applications. 2D alloys have been demonstrated when two components crystallized in the same phase, and their bandgaps displayed predictable monotonic variation. By stabilizing previously unobserved compositions and phases of GaSe1−xTe                  x                 at nanoscales on GaAs(111), we demonstrate abnormal band bowing effects and phase instability region when components crystallize in different phases. Advanced microscopy and spectroscopy measurements show as tellurium is alloyed into GaSe, nanostructures undergo hexagonal to monoclinic and isotropic to anisotropic transition. There exists an instability region (0.56 u003c x u003c 0.67) where both phases compete and coexist, and two different bandgap values can be found at the same composition leading to anomalous band bowing effects. Results highlight unique alloying effects, not existing in single-phase alloys, and phase engineering routes for potential applications in photonic and electronics.",
        "keywords": "",
        "authors": [
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Bin Chen",
                "org": ""
            },
            {
                "name": "Mark Blei",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Shery L. Y. Chang",
                "org": ""
            },
            {
                "name": "Kedi Wu",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Houlong L. Zhuang",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Nature Communications",
        "year": 2018
    },
    "srxHTYdp": {
        "id": "srxHTYdp",
        "title": "Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: Optimization of cellular potency",
        "abstract": "Basic lipophilic substituents dramatically improved the cellular potency of a previously disclosed series of pyrazole-based arylalkyne cathepsin S inhibitors. The incorporation of substituted benzylamines in the para position of the arylalkyne maintained enzymatic activity (hCatS IC50=80–420nM) and imparted cellular potency (IC50=0.8–4.0μM). Further refinement of the morpholine portion of the pharmacophore enabled the identification of bicyclic piperidines with enhanced affinity for CatS (IC50=10–30nM) and sub-micromolar cellular potency (JY Ii IC50=200–720nM).",
        "keywords": [
            "Cathepsin",
            "Protease",
            "Invariant chain",
            "Lysosomotropism"
        ],
        "authors": [
            {
                "name": "Michael K. Ameriks",
                "org": "Corresponding author."
            },
            {
                "name": "Hui Cai",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "James P. Edwards",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Damara Gebauer",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Elizabeth Gleason",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Yin Gu",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Lars Karlsson",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Steven Nguyen",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Siquan Sun",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Robin L. Thurmond",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            },
            {
                "name": "Jian Zhu",
                "org": "Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, United States"
            }
        ],
        "venue": "Bioorganic & Medicinal Chemistry Letters",
        "year": 2009
    },
    "q2R5Dlnr": {
        "id": "q2R5Dlnr",
        "title": "Installation, system-level control strategy and commissioning of the Nanjing UPFC project",
        "abstract": "The Nanjing unified power flow controller (UPFC) project, which is the worldu0027s first modular multilevel converter based UPFC (MMC-UPFC) project, has been put into operation in the Nanjing Western Power Grid by State Grid Corporation of China since December 14, 2015. The project comprises three 60 MVA converters and is applied to a 220 kV ac system. The installation of the project is reported in this paper, including the optimized structure and the layout. Besides, the UPFC systemlevel control strategy is discussed. With the proposed system-level control strategy, a key transmission section of the Nanjing Western Power Grid will be operated at the preset operating point under the normal condition. While, the power flows of the transmission lines in the transmission section can be controlled within the line loading limits under fault conditions. The commissioning test results of the Nanjing UPFC project and the proposed system-level control strategy are also presented. The waveforms recorded show that the project performs well under the normal operation condition and the fault conditions. The security of the Nanjing Western Power Grid is enhanced by the installation of the Nanjing UPFC project.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaomei Yang",
                "org": "State Grid Jiangsu Electric Power Company, Nanjing, China"
            },
            {
                "name": "Weiyuan Wang",
                "org": "State Grid Jiangsu Electric Power Company, Nanjing, China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic, Research Institute, Nanjing, China"
            },
            {
                "name": "Pengcheng Song",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            }
        ],
        "venue": "power and energy society general meeting",
        "year": 2017
    },
    "dkrr4MOv": {
        "id": "dkrr4MOv",
        "title": "N-methyl threonine analogues of deglycobleomycin A2: Synthesis and evaluation",
        "abstract": "The synthesis of 5 and its D-allo-threonine epimer 6 and the comparison of their DNA cleavage efficiency and selectivity with that of deglycobleomycin A(2) (3) are detailed. The studies illustrate that N-methylation of the L-threonine subunit within deglycobleomycin A(2) dramatically reduces the DNA cleavage efficiency (10-15-fold), weakens and nearly abolishes the inherent DNA cleavage selectivity, but has little effect on the inherent oxidation capabilities of the activated Fe(III) complexes. The results are consistent with a previously unrecognized prominent role for the threonine NH and the potential importance of a hydrogen bond to the Fe(III) hydroperoxide complex of bleomycin or a subsequent activated complex implicated in recent structural models. (C) 1997 Elsevier Science Ltd.",
        "keywords": [],
        "authors": [
            {
                "name": "Dale L. Boger",
                "org": "Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Shuji Teramoto",
                "org": "Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1997
    },
    "fTHTR3In": {
        "id": "fTHTR3In",
        "title": "Changes of plasma TNF-α in the rats with isoproterenol-induced congestive heart failure",
        "abstract": "Objective: Recent studies have suggested that congestive heart failure(CHF) is related to neuroendocrine system and cytokines,and its activation contributes to myocardial remodeling and leads to the development and progression of CHF.Tumour necrosis factor-α(TNF-α) is one of the most important factors.This study intends to establish the animal model of isoproterenol(ISO)-induced CHF in rats and to study the changes of serum TNF-α.Methods:Male SD rats were randomly allocated to the ISO-induced CHF group(n=50) receiving two subcutaneous injections of 170mg ISO per kilogram of body and the healthy control group(n=10) receiving two subcutaneous injections of 0.25ml normal saline.At 18th week,the hemodynamic parameters including HR,LVSP,LVEDP and ±dp/dtmax were assessed.TNF-α in plasma were all detected.Results:Compared with the control group,the LVSP、±dp/dtmax significantly decreased and the HR,LVEDP enlarged notably in CHF group(P<0.01).Also the mass ratio of left ventricle to body and the concentration of TNF-α increased distinctly(P<0.01).Conclusion:Activation of plasma TNF-α observed in high-dose isoproterenol-induction rat model of CHF.",
        "keywords": [
            "TNF-α",
            "Myocardial remodeling",
            "SD rats",
            "Chronic heart failure",
            "Isoproterenol"
        ],
        "authors": [
            {
                "name": "LI Zheng",
                "org": "1.Department of Medical Affairs,"
            },
            {
                "name": "GUO Han",
                "org": "2.Department of Integrated TCM and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "2.Department of Integrated TCM and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "2.Department of Integrated TCM and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "2.Department of Integrated TCM and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "y0ftbufv": {
        "id": "y0ftbufv",
        "title": "Panax notoginseng saponins alleviate adjuvant arthritis in rats",
        "abstract": "Objective:To investigate the therapeutic effects and the action mechanism of panax notoginseng saponins(PNS)on adjuvant arthritis(AA)in rats.Methods:Twenty-four male Lewis rats were randomly divided into a normal control,a model,a PNS and a DM group.Freund's complete adjuvant(FCA) was used to induce AA in the in the latter three groups.Polyarthritis indexes were obtained and the tendency of body weight changes was monitored for the AA rats.The products of the tumor necrosis factor(TNF)and interleukin-1β(IL-1β)were determined by radio immunoassay.Results: Compared with the AA models,intraperitoneal injection of PNS for 2 weeks from the 15 th day after immunization significantly improved the polyarthritic symptoms,reduced the products of TNF and IL-1βfrom the serum,and effected no body weight changes in the AA rats.Conclusion:PNS can alleviate AA in rats,which may be attributed to its inhibitory effect on the products of proimflammatory cytokines of TNF and IL-1β.",
        "keywords": [
            "Interleukin-1β",
            "Tumor necrosis factor",
            "Adjuvant arthritis",
            "Panax notoginseng saponin"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "HU Bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "jBZfJgWM": {
        "id": "jBZfJgWM",
        "title": "Effect of Acupuncture on Serum Leptin Level in Patients with Type Ⅱ Diabetes Mellitus",
        "abstract": "Objective To study the relationship between serum leptin and insulin resistance,and to analyze the effect of acupuncture on serum leptin level in patients with type-Ⅱ diabetes mellitus(DM).Methods A total of 80 type-Ⅱ DM patients were randomized into acupuncture and medication groups.Acupuncture was applied to Yishu(EX),Feishu(BL13),Pishu(BL 20),etc.according to syndrome identification.The treatment was given once every other day for 12 weeks.For patients in the medication group,Glibenclamide(2.5-7.5 mg/time,1-2 times/d according to blood sugar level) was given for 12 weeks.Fasting blood glucose(FBG),fasting insulin(FINS) and fasting leptin(FLP) were detected by using glucose oxidase method,radioimmunoassay and ELISA,respectively.Insulin sensitivity index(ISI) and homeostasis model assessment-insulin resistance(HOMA-IR) were calculated.Results In comparison with pre-treatment,FBG levels and HOMA-IR in both acupuncture and medication groups,and FINS and FLP levels in the acupuncture group were decreased significantly(P<0.01),while ISI in both acupuncture and medication groups,and FINS level in the medication group were increased remarkably after the treatment(P<0.01).Comparison between two groups showed that after the treatment,FINS and FLP levels,and HOMA-IR of the acupuncture group were considerably lower than those of the medication group(P<0.01),while ISI of the acupuncture group was significantly higher than that of the medication group(P<0.01).Conclusion Acupuncture therapy is effective in lowering FLP level,which may contribute to its clinical effect in improving type-Ⅱ DM.",
        "keywords": [
            "Acupuncture therapy",
            "Type-Ⅱ diabetes mellitus",
            "Insulin resistance",
            "Serum leptin"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": "Department of Integrated Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Acupuncture Research",
        "year": 2011
    },
    "ZfTv560S": {
        "id": "ZfTv560S",
        "title": "An argument about 'restraint subsequent to disorders caused by unrestrained excess'",
        "abstract": "The theory of 'restraint subsequent to disorders caused by unrestrained excess' is the essence of the doctrine on yunqi(five successive evolutive phases corresponding to five elements) as well as an important part of the theory of Chinese medicine.It reveals a phenomenon about growth,transformation and restriction that commonly exists in the natural world.Interpromotion and interrestraint of the five elements,opposition and mutual basement of Yinyang,system science,natural phenomena and cultural phenomena are all governed by this theory.This article approaches the theory of 'restraint subsequent to disorders caused by unrestrained excess' from the viewpoint of nature,physiology,pathogenesis,therapeutics and practice,pointing out its significance in the development and clinical modernization of Chinese medicine.",
        "keywords": [
            "Interpromotion and interrestraint",
            "Restraint subsequent to disorders caused by unrestrained excess",
            "Five elements"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "KvzwIhHK": {
        "id": "KvzwIhHK",
        "title": "A Research on Community Planning System Reconstruction and New Mechanism in China from the Perspective of Low-Carbon",
        "abstract": "Based on the subject of Chinese low-carbon community planning,this paper reviews important progresses obtained in the research of low-carbon community planning theories and practice efforts.By analyzing present status and trends of development of community planning home and aboard,and exploring forms,impetus and mechanism of community planning according to systematic theory,this paper puts forward that framework and implementation of low-carbon community planning should be developed from ways of planning system,planning process and planning strategies.",
        "keywords": [
            "community planning",
            "low-carbon",
            "system reconstruction",
            "mechanism exploration"
        ],
        "authors": [
            {
                "name": "YU Kanhua",
                "org": "College of Architecture,Chang'an University,Xi'an Shaanxi ,China"
            },
            {
                "name": "CAI Hui",
                "org": "College of Architecture,Chang'an University,Xi'an Shaanxi ,China"
            }
        ],
        "venue": "Ecological Economy",
        "year": 2012
    },
    "6qy1Dpk3": {
        "id": "6qy1Dpk3",
        "title": "Effect of tanshinone ⅡA on the expression of TNF-α and NF-κB in rats with pressure overload",
        "abstract": "Objective To observe the changes of TNF-α and NF-κB expressions in rats with pressure overload and to explore the protective effects of tanshinoneⅡA(TanⅡA) on myocardial fibrosis.Methods Thirty-two SD rats induced by abdominal aorta constriction preparation were randomly divided into 4 groups,which were sham group,model group,TanⅡA group,and captopril group(each n=8).The model of pressure overload-induced myocardial fibrosis was successfully established after 4 weeks of operation.After four weeks of TanⅡA treatment and 8 weeks later,heart mass indexes were estimated in concurrent evaluation of myocardial histology.Myocardial hydroxyproline content and serum TNF-α were measured by method of ELISA.Immunohistochemistry was used to test myocardial NF-κB p65 content.Results Compared with sham group,heart mass indexes,myocardial hydroxyproline content,serum TNF-α and myocardial NF-κB p65 content increased in the model group(P<0.01).Compared with model group,heart mass indexes,myocardial hydroxyproline content,serum TNF-α and myocardial NF-κB p65 content decreased in the TanⅡA group(P<0.01).Conclusions The expressions of serum TNF-α and myocardial NF-κB p65 protein significantly increased in pressure overload rat myocardium,indicating that TNF-α and NF-κB signaling mediated myocardial inflammation in the pressure overload in rat myocardial fibrosis and development.TanⅡA could alleviate myocardial fibrosis by inhibition of TNF-α and NF-κB signaling pathway.",
        "keywords": [
            "tanshinone Ⅱ A",
            "TNF-α",
            "pressure overload",
            "myocardial fibrosis",
            "NF-κB"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,P.R.China"
            },
            {
                "name": "CAI Jia-yu",
                "org": "Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,P.R.China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,P.R.China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Nanjing General Hospital,Nanjing Military Area Command,Nanjing ,P.R.China"
            }
        ],
        "venue": "Shandong Medical Journal",
        "year": 2013
    },
    "IuqZRwTj": {
        "id": "IuqZRwTj",
        "title": "Age at last birth and endometrial cancer risk: Pooled analysis in the Epidemiology of Endometrial Cancer Consortium",
        "abstract": "Some studies show that childbearing at older age is associated with lower risk of endometrial cancer, but whether the association is independent of number of children or other factors still requires clarification. We pooled individual-level data from epidemiologic studies in the Epidemiology of Endometrial Cancer Consortium (E2C2). Data on age at last birth and/or last pregnancy were available from 14 studies: 11 case-control studies and 3 cohort studies; the latter were analyzed using a nested case-control design. A total of 9,613 endometrial cancer cases and 17,112 controls were included in the analysis. The majority of women were White (82%) and older than 55 years (69%). We estimated the effects of age at last birth using data from 12 studies and age at last pregnancy using data from 10 studies on the risk of endometrial cancer by calculating odds ratios (OR) and 95% confidence intervals (95% CI) using …",
        "keywords": "",
        "authors": [
            {
                "name": "Veronica W Setiawan",
                "org": ""
            },
            {
                "name": "Stalo Karageorgi",
                "org": ""
            },
            {
                "name": "Sandra Deming",
                "org": ""
            },
            {
                "name": "Kristin Anderson",
                "org": ""
            },
            {
                "name": "Leslie Bernstein",
                "org": ""
            },
            {
                "name": "Louise Brinton",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "James R Cerhan",
                "org": ""
            },
            {
                "name": "Chu Chen",
                "org": ""
            },
            {
                "name": "Wendy Cozen",
                "org": ""
            },
            {
                "name": "Jennifer A Doherty",
                "org": ""
            },
            {
                "name": "Jo L Freudenheim",
                "org": ""
            },
            {
                "name": "Marc T Goodman",
                "org": ""
            },
            {
                "name": "Pamela Horn-Ross",
                "org": ""
            },
            {
                "name": "Jolanta Lissowska",
                "org": ""
            },
            {
                "name": "Galina Lurie",
                "org": ""
            },
            {
                "name": "Thomas Mack",
                "org": ""
            },
            {
                "name": "Rayna K Matsuno",
                "org": ""
            },
            {
                "name": "Susan E McCann",
                "org": ""
            },
            {
                "name": "Kristen Moysich",
                "org": ""
            },
            {
                "name": "Malcolm C Pike",
                "org": ""
            },
            {
                "name": "Timothy R Rebbeck",
                "org": ""
            },
            {
                "name": "Kim Robien",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Amanda B Spurdle",
                "org": ""
            },
            {
                "name": "Brian L Strom",
                "org": ""
            },
            {
                "name": "Giske Ursin",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Penny M Webb",
                "org": ""
            },
            {
                "name": "Noel S Weiss",
                "org": ""
            },
            {
                "name": "Nicolas Wentzensen",
                "org": ""
            },
            {
                "name": "Hannah P Yang",
                "org": ""
            },
            {
                "name": "Immaculata De Vivo",
                "org": ""
            },
            {
                "name": "Australian National Endometrial Cancer Study Group",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "ybbKb9So": {
        "id": "ybbKb9So",
        "title": "Abdominal adiposity and mortality in Chinese women.",
        "abstract": "Increased abdominal adiposity has been linked to an increase in mortality in populations where many are overweight or obese; it is unclear whether the same is true in relatively lean populations.We examined the association between waist-hip ratio and mortality in the Shanghai Women's Health Study, a population-based, prospective cohort study of Chinese women aged 40 to 70 years enrolled from December 28, 1996, through May 23, 2000, 95% of whom had a body mass index (calculated as weight in kilograms divided by height in meters squared) of less than 30.0. Included in this analysis were 72 773 nonsmoking women who had anthropometrics taken by trained interviewers at enrollment and who were followed up through December 31, 2004. Deaths were ascertained by biennial home visits and linkage with the vital statistics registry.During a mean follow-up of 5.7 years, 1456 deaths occurred. The waist-hip ratio was positively and significantly associated with deaths from all causes, cardiovascular disease, and diabetes (P<.01 for trend). A less significant positive association was found for death from cancer. After adjustment for body mass index and other potential confounders, the relative risks of total mortality were 1 (reference group), 1.28 (95% confidence interval [CI], 1.04-1.58), 1.40 (95% CI, 1.14-1.72), 1.54 (95% CI, 1.26-1.88), and 1.95 (95% CI, 1.60-2.38) across the lowest to the highest waist-hip ratio quintiles. The positive association appeared to be more evident in women with a lower body mass index. The relative risks of total mortality comparing the extreme waist-hip ratio quintiles were 2.36 (95% CI, 1.71-3.27), 1.60 (95% CI, 1.10-2.34), and 1.46 (95% CI, 0.97-2.20) for women with a body mass index of less than 22.3, 22.3 to 25.1, and 25.2 or greater, respectively.Abdominal adiposity independently predicts mortality risk, particularly for nonobese women.",
        "keywords": [],
        "authors": [
            {
                "name": "Xianglan Zhang",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "Archives of internal medicine",
        "year": 2007
    },
    "cpxMjrjS": {
        "id": "cpxMjrjS",
        "title": "Synthesis and evaluation of potential N π and N σ metal chelation sites within the β-hydroxy-l-histidine subunit of bleomycin A 2 : Functional characterization of imidazole N π metal complexation",
        "abstract": "The synthesis and evaluation of 4 and 5, fully functionalized deglycobleomycin A(2) (2) analogues incorporating an oxazole and a pyrrole in place of the beta-hydroxy-L-histidine imidazole, are detailed, The oxazole agent is only capable of N-pi metal complexation through a form related to the N-1-H imidazole tautomer of bleomycin A(2) (1) while the pyrrole agent may potentially mimic the N-sigma metal complexation capabilities of the imidazole N-3-H tautomer. Metal complexes (Fe-II, Fe-III) of 4 and 5 were found to cleave duplex DNA in the presence of O-2 (Fe-II) or H2O2 (Fe-III). The oxazole agent 4 which is incapable of N-sigma metal chelation was found to behave analogous to, albeit slightly less effectively than, deglycobleomycin A(2) resulting in the characteristic 5'-GC/5'-GT sequence selective cleavage of duplex DNA directly confirming that imidazole/oxazole N-pi metal chelation is sufficient for functional reactivity. Importantly, the effective substitution of the oxazole O-1 for the histidine N-1 further illustrates that this group does not require deprotonation upon metal complexation, oxygen activation, or the ensuing oxidation reactions, that the functional bleomycin A(2) tautomer is the imidazole N-1-H tautomer, and that the imidazole N-1-H functionality is not contributing to the polynucleotide recognition through H-bonding to the phosphate backbone or nucleotide bases. In contrast, the pyrrole agent 5 which is incapable of N-pi metal chelation, but possesses the capabilities of functioning as a N-sigma metal donor was also found to cleave duplex DNA, but does so in a nonsequence selective fashion with a significantly reduced efficiency and a diminished double to single strand cleavage ratio both only slightly above that of background iron itself. These observations are analogous to those made with 3 which lacks the imidazole altogether and further support the observations that N-pi coordination, not N-sigma coordination, of the imidazole is required for the functional activity of bleomycin A(2).",
        "keywords": [
            "nucleotides",
            "iron"
        ],
        "authors": [
            {
                "name": "dale l boger",
                "org": ""
            },
            {
                "name": "timothy m ramsey",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1996
    },
    "9LgwrseO": {
        "id": "9LgwrseO",
        "title": "Association of genetic polymorphisms in cell-cycle control genes and susceptibility to endometrial cancer among Chinese women.",
        "abstract": "Although genetic variations in cell-cycle control genes have been previously linked to cancer risk, no study has specifically evaluated the role of these gene variants in endometrial carcinogenesis. Using data from the Shanghai Endometrial Cancer Study, a population-based case-control study with 1,199 cases and 1,212 age-matched controls (1997-2003), the authors carried out a systematic evaluation of the association of cell-cycle control genes with endometrial cancer risk. Sixty-five tagging or potentially functional single nucleotide polymorphisms in the CCNB1, CCND1, CCNE1, CDK2, CDK4, CDK6, CDKN1A, CDKN1B, and CDKN2A genes were genotyped and evaluated. Three single nucleotide polymorphisms in the CDKN1B gene (rs11055027, rs3759216, and rs34330) were related to endometrial cancer risk, although only the association with rs34330 remained statistically significant after adjustment for multiple comparisons. The odds ratios for rs34330 were 1.33 (95% confidence interval (CI): 1.06, 1.66) and 1.51 (95% CI: 1.16, 1.94) for the CT and TT genotypes, respectively, compared with the CC genotype. In vitro luciferase reporter assays showed that the minor allele (A) in rs3759216, which was associated with decreased endometrial cancer risk (odds ratio = 0.73, 95% CI: 0.56, 0.94) without adjustment for multiple comparisons, significantly increased promoter activity. These findings suggest that polymorphisms of the CDKN1B gene may play a role in endometrial carcinogenesis.",
        "keywords": [
            "cell cycle",
            "China",
            "endometrial neoplasms",
            "polymorphism",
            " genetic",
            "polymorphism",
            " single nucleotide",
            "women"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Dept Epidemiol, Inst Canc, Shanghai Canc Inst, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Shimian Qu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Jiao Tong Univ, Dept Epidemiol, Inst Canc, Shanghai Canc Inst, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Epidemiol Ctr, Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF EPIDEMIOLOGY",
        "year": 2011
    },
    "uiE4Zix7": {
        "id": "uiE4Zix7",
        "title": "EFFECT OF BUSHEN PRESCRIPTION ON PLASMA ENDOTHELIN IN RATS WITH PRESSURE OVERLOAD",
        "abstract": "Objective:To observe the effect of bushen prescription on plasma endithelin level in pressure overload rats.Methods:60 male rats were divided into 5 groups at random,sham-operation,model,captopril,bushen prescription big and small dose groups,each group contained 12 rats,each group was given the corresponding medicine for days.Observing the left ventricular mass index(LVMI),left ventricular myocardium pathological changes were observed by light scope,plasma ET was determined by radioimmunoassay.Results:The LVMI,plasma ET level in model group were obviously elevated,they were higher than those in sham operation group(P<0.01),the LVMI,plasma ET level were obviously lowered after treated,there was significant difference between bushen prescription groups and control group(P<0.01).Conclusion :Bushen prescription can protect myocardium of left ventricular hypertrophy from pressure overload by lowering ET level,its effect was similar to captopril.",
        "keywords": [],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of Nanjing Military Area Command,Nanjing "
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Nanjing General Hospital of Nanjing Military Area Command,Nanjing "
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Nanjing General Hospital of Nanjing Military Area Command,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Traditional Medical Science and Technology",
        "year": 2010
    },
    "tFVy36HM": {
        "id": "tFVy36HM",
        "title": "Association between educational level and total and cause-specific mortality: a pooled analysis of over 694 000 individuals in the Asia Cohort Consortium.",
        "abstract": "Objective To study the association of educational level and risk of death from all causes, cardiovascular disease (CVD) and cancer among Asian populations. Design A pooled analysis of 15 population-based cohort studies. Setting and participants 694434 Asian individuals from 15 prospective cohorts within the Asia Cohort Consortium. Interventions None. Main outcome measures HRs and 95% CIs for all-cause mortality, as well as for CVD-specific mortality and cancer-specific mortality. Results A total of 694434 participants (mean age at baseline=53.2 years) were included in the analysis. During a mean follow-up period of 12.5 years, 103023 deaths were observed, among which 33939 were due to cancer and 34645 were due to CVD. Higher educational levels were significantly associated with lower risk of death from all causes compared with a low educational level (<= primary education); HRs and 95% CIs for secondary education, trade/technical education and >= university education were 0.88 (0.85 to 0.92), 0.81 (0.73 to 0.90) and 0.71 (0.63 to 0.80), respectively (p(trend)=0.002). Similarly, HRs (95% CIs) were 0.93 (0.89 to 0.97), 0.86 (0.78 to 0.94) and 0.81 (0.73 to 0.89) for cancer death, and 0.88 (0.83 to 0.93), 0.77 (0.66 to 0.91) and 0.67 (0.58 to 0.77) for CVD death with increasing levels of education (both p(trend) <0.01). The pattern of the association among East Asians and South Asians was similar compared with <less than or equal to>primary education; HR (95%CI) for all-cause mortality associated with >= university education was 0.72 (0.63 to 0.81) among 539724 East Asians (Chinese, Japanese and Korean) and 0.61 (0.54 to 0.69) among 154710 South Asians (Indians and Bangladeshis). Conclusion Higher educational level was associated with substantially lower risk of death among Asian populations.",
        "keywords": [
            "education",
            "cancer",
            "Asia",
            "mortality",
            "cardiovascular"
        ],
        "authors": [
            {
                "name": "Keming Yang",
                "org": "Indiana Univ, Richard M Fairbanks Sch Publ Hlth, Dept Epidemiol, Indianapolis, IN 46204 USA"
            },
            {
                "name": "Ying Zhang",
                "org": "Univ Nebraska Med Ctr, Coll Publ Hlth, Dept Biostat, Omaha, NE USA"
            },
            {
                "name": "Eiko Saito",
                "org": "Natl Canc Ctr, Ctr Canc Control & Informat Serv, Div Canc Stat Integrat, Tokyo, Japan"
            },
            {
                "name": "Md Shafiur Rahman",
                "org": "Univ Tokyo, Grad Sch Med, Dept Global Hlth Policy, Tokyo, Japan"
            },
            {
                "name": "Prakash Chandra Gupta",
                "org": "Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, India"
            },
            {
                "name": "Norie Sawada",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Akiko Tamakoshi",
                "org": "Hokkaido Univ, Fac Med, Sapporo, Hokkaido, Japan"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Jiao Tong Univ, Sch Med, State Key Lab Oncogene & Related Genes, Renji Hosp,Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Woon-Puay Koh",
                "org": "Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore, Singapore"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Div Epidemiol,Dept Med, Nashville, TN USA"
            },
            {
                "name": "Ichiro Tsuji",
                "org": "Tohoku Univ, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Atsuko Sadakane",
                "org": "Radiat Effects Res Fdn, Dept Epidemiol, Hiroshima, Japan"
            },
            {
                "name": "Chisato Nagata",
                "org": "Gifu Univ, Grad Sch Med, Dept Epidemiol & Prevent Med, Gifu, Japan"
            },
            {
                "name": "San-Lin You",
                "org": "Fu Jen Catholic Univ, Big Data Res Ctr, Sch Med, Taipei, Taiwan"
            },
            {
                "name": "Jian-Min Yuan",
                "org": "Univ Pittsburgh, UPMC Hillman Canc Ctr, Div Canc Control & Populat Sci, Pittsburgh, PA USA"
            },
            {
                "name": "Myung-Hee Shin",
                "org": "Sungkyunkwan Univ, Sch Med, Dept Social & Prevent Med, Seoul, South Korea"
            },
            {
                "name": "Yu Chen",
                "org": "NYU, Sch Med, Dept Environm Med, Dept Populat Hlth, New York, NY USA"
            },
            {
                "name": "Wen-Harn Pan",
                "org": "Acad Sinica, Inst Biomed Sci, Taipei, Taiwan"
            },
            {
                "name": "Mangesh S Pednekar",
                "org": "Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, India"
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Div Epidemiol,Dept Med, Nashville, TN USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Sch Med, State Key Lab Oncogene & Related Genes, Renji Hosp,Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Kotaro Ozasa",
                "org": "Radiat Effects Res Fdn, Dept Epidemiol, Hiroshima, Japan"
            },
            {
                "name": "Yasutake Tomata",
                "org": "Tohoku Univ, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Seiki Kanemura",
                "org": "Tohoku Univ, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Yumi Sugawara",
                "org": "Tohoku Univ, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Keiko Wada",
                "org": "Gifu Univ, Grad Sch Med, Dept Epidemiol & Prevent Med, Gifu, Japan"
            },
            {
                "name": "Renwei Wang",
                "org": "Univ Pittsburgh, UPMC Hillman Canc Ctr, Div Canc Control & Populat Sci, Pittsburgh, PA USA"
            },
            {
                "name": "Yoon-Ok Ahn",
                "org": "Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea"
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Seoul Natl Univ, Coll Med, Armed Forces Capital Hosp, Seoul, South Korea"
            },
            {
                "name": "Habibul Ahsan",
                "org": "Univ Chicago, Dept Publ Hlth Sci, Chicago, IL 60637 USA"
            },
            {
                "name": "Kee Seng Chia",
                "org": "Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Epidemiol Program, Singapore, Singapore"
            },
            {
                "name": "Paolo Boffetta",
                "org": "Icahn Sch Med Mt Sinai, New York, NY 10029 USA"
            },
            {
                "name": "Daehee Kang",
                "org": "Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea"
            },
            {
                "name": "John D Potter",
                "org": "Massey Univ, Ctr Publ Hlth Res, Wellington, New Zealand"
            },
            {
                "name": "Manami Inoue",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Div Epidemiol,Dept Med, Nashville, TN USA"
            },
            {
                "name": "Hongmei Nan",
                "org": "Indiana Univ, Richard M Fairbanks Sch Publ Hlth, Dept Epidemiol, Indianapolis, IN 46204 USA"
            }
        ],
        "venue": "BMJ OPEN",
        "year": 2019
    },
    "YOJBaVYD": {
        "id": "YOJBaVYD",
        "title": "Effects of panax notoginseng saponins on adjuvant arthritis and expression of NF-κB in rats",
        "abstract": "Objective To observe the effects of panax notoginseng saponins(PNS) on ankle joint arthritis and expression of NF-κB in adjuvant arthritis(AA) rats and investigate the therapeutic mechanism of PNS in RA. Methods Twenty-four male lewis rats were randomly divided into four groups: normal control group, model group, PNS group and DM group. AA rat models were established by intradermal injection of Complete Freund′s adjuvant. Polyarthritis indices were scored. Pathological sections of ankle joint in rats were made and then stained by HE method and immunohistochemical method respectively. Infiltration of inflammatory cell and hyperplasia of synovioblast in HE-stained pathological sections were observed under microscope and expression of NF-κB was observed by semi-quantitative immunohistochemical method. Results PNS were given to rats by intraperitoneal injection for 2 weeks after immunization. Compared with AA model group, the polyarthritic symptoms of PNS group rats were improved significantly (P < 0.05), infiltration of inflammatory cell of PNS group rats was improved significantly in HE-stained pathological sections (P < 0.05) and expression of NF-κB of PNS group was decreased in pathological sections stained by immunohistochemical method (P < 0.05). Conclusion PNS has therapeutic effects on AA in rats, which may be related to improving arthrosynovitis and inhibiting expression of NF-κB.",
        "keywords": [
            "experimental NF-kappa B Panax notoginseng saponins",
            "Arthritis"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            },
            {
                "name": "QIAN Shan-feng",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            },
            {
                "name": "GUO Jun-hao",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            },
            {
                "name": "HU Bing",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            },
            {
                "name": "CAI Hui",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2008
    },
    "iMH4QHGK": {
        "id": "iMH4QHGK",
        "title": "Gate-tunable diode-like current rectification and ambipolar transport in multilayer van der Waals ReSe 2 /WS 2 p-n heterojunctions.",
        "abstract": "Vertically stacked van der Waals (vdW) heterojunctions of two-dimensional (2D) transition metal dichalcogenides (TMDs) have attracted a great deal of attention due to their fascinating properties. In this work, we report two important gate-tunable phenomena in new artificial vdW p-n heterojunctions created by vertically stacking p-type multilayer ReSe2 and n-type multilayer WS2: (1) well-defined strong gate-tunable diode-like current rectification across the p-n interface is observed, and the tunability of the electronic processes is attributed to the tunneling-assisted interlayer recombination induced by majority carriers across the vdW interface; (2) the distinct ambipolar behavior under gate voltage modulation both at forward and reverse bias voltages is found in the vdW ReSe2/WS2 heterojunction transistors and a corresponding transport model is proposed for the tunable polarity behaviors. The findings may provide some new opportunities for building nanoscale electronic and optoelectronic devices.",
        "keywords": "",
        "authors": [
            {
                "name": "Cong Wang",
                "org": "The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEDA Institute of Applied Physics, Nankai University, Tianjin 300457, China and CAS Center of Excellence for Nanoscience, CAS Key Laboratory of Nanosystem and Hierarchical Fabrication, National Center for Nanoscience and Technology, Beijing 100190, China. liuq@nanoctr.cn."
            },
            {
                "name": "Shengxue Yang",
                "org": "School of Materials Science and Engineering, Beihang University, Beijing 100191, China."
            },
            {
                "name": "Wenqi Xiong",
                "org": "Department of Physics, Henan Normal University, Xinxiang 453007, China."
            },
            {
                "name": "Congxin Xia",
                "org": "Department of Physics, Henan Normal University, Xinxiang 453007, China."
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA. sefaattin.tongay@asu.edu."
            },
            {
                "name": "Bin Chen",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA. sefaattin.tongay@asu.edu."
            },
            {
                "name": "Xiaoting Wang",
                "org": "State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Science, Beijing 100083, China. jbli@semi.ac.cn."
            },
            {
                "name": "Xinzheng Zhang",
                "org": "The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEDA Institute of Applied Physics, Nankai University, Tianjin 300457, China."
            },
            {
                "name": "Zhongming Wei",
                "org": "State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Science, Beijing 100083, China. jbli@semi.ac.cn."
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85287, USA. sefaattin.tongay@asu.edu."
            },
            {
                "name": "Jingbo Li",
                "org": "State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Science, Beijing 100083, China. jbli@semi.ac.cn."
            },
            {
                "name": "Qian Liu",
                "org": "The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEDA Institute of Applied Physics, Nankai University, Tianjin 300457, China and CAS Center of Excellence for Nanoscience, CAS Key Laboratory of Nanosystem and Hierarchical Fabrication, National Center for Nanoscience and Technology, Beijing 100190, China. liuq@nanoctr.cn."
            }
        ],
        "venue": "Physical chemistry chemical physics : PCCP",
        "year": 2016
    },
    "X3VtSUyy": {
        "id": "X3VtSUyy",
        "title": "[Acupuncture Treatment Reduces Body Weight Possibly by Down-regulating Insulin and Leptin Resistance, and Up-regulating Soluble Leptin Receptor Level in Prediabetic Patients].",
        "abstract": "Acupuncture can induce body weight loss, down-regulate FINS, insulin resistance and LP resistance, and up-regulate sOB-R content in prediabetic patients, displaying a positive role in the treatment of prediabetes.",
        "keywords": [
            "Acupuncture treatment",
            "Insulin resistance",
            "Leptin",
            "Prediabetes",
            "Soluble leptin receptor"
        ],
        "authors": [
            {
                "name": "Zhi-Ming Zhao",
                "org": "The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China; Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Chun-Li Liu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Qun-Yan Zhang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Bei-Bei Zhang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Jun-Hao Guo",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Ai-Hong Yuan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            },
            {
                "name": "Hui Cai",
                "org": "The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China; Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of People's Liberation Army, Nanjing 210002."
            }
        ],
        "venue": "Zhen ci yan jiu = Acupuncture research",
        "year": 2018
    },
    "L7h4oQcj": {
        "id": "L7h4oQcj",
        "title": "Combined impact of lifestyle-related factors on total and cause-specific mortality among chinese women: Prospective cohort study",
        "abstract": "Background: Although cigarette smoking, excessive alcohol drinking, obesity, and several other well-studied unhealthy lifestyle-related factors each have been linked to the risk of multiple chronic diseases and premature death, little is known about the combined impact on mortality outcomes, in particular among Chinese and other non-Western populations. The objective of this study was to quantify the overall impact of lifestyle-related factors beyond that of active cigarette smoking and alcohol consumption on all-cause and cause-specific mortality in Chinese women. Methods and Findings: We used data from the Shanghai Women's Health Study, an ongoing population-based prospective cohort study in China. Participants included 71,243 women aged 40 to 70 years enrolled during 1996-2000 who never smoked or drank alcohol regularly. A healthy lifestyle score was created on the basis of five lifestyle-related factors shown to be independently associated with mortality outcomes (normal weight, lower waist-hip ratio, daily exercise, never exposed to spouse's smoking, higher daily fruit and vegetable intake). The score ranged from zero (least healthy) to five (most healthy) points. During an average follow-up of 9 years, 2,860 deaths occurred, including 775 from cardiovascular disease (CVD) and 1,351 from cancer. Adjusted hazard ratios for mortality decreased progressively with an increasing number of healthy lifestyle factors. Compared to women with a score of zero, hazard ratios (95% confidence intervals) for women with four to five factors were 0.57 (0.44-0.74) for total mortality, 0.29 (0.16-0.54) for CVD mortality, and 0.76 (0.54-1.06) for cancer mortality. The inverse association between the healthy lifestyle score and mortality was seen consistently regardless of chronic disease status at baseline. The population attributable risks for not having 4-5 healthy lifestyle factors were 33% for total deaths, 59% for CVD deaths, and 19% for cancer deaths. Conclusions: In this first study, to our knowledge, to quantify the combined impact of lifestyle-related factors on mortality outcomes in Chinese women, a healthier lifestyle pattern-including being of normal weight, lower central adiposity, participation in physical activity, nonexposure to spousal smoking, and higher fruit and vegetable intake-was associated with reductions in total and cause-specific mortality among lifetime nonsmoking and nondrinking women, supporting the importance of overall lifestyle modification in disease prevention.",
        "keywords": [
            "cohort studies",
            "prospective studies",
            "cohort study",
            "waist hip ratio"
        ],
        "authors": [
            {
                "name": "Sarah J. Nechuta",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wongho Chow -",
                "org": "NCI, Div Canc Epidemiol & Genet, Rockville, MD USA"
            },
            {
                "name": "Butian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, Rockville, MD USA"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wanqing Wen",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yutang Gao -",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37212 USA"
            }
        ],
        "venue": "PLOS MEDICINE",
        "year": 2010
    },
    "EEiGS7It": {
        "id": "EEiGS7It",
        "title": "Novel genetic markers of breast cancer survival identified by a genome-wide association study",
        "abstract": "Only two genome-wide association studies (GWAS) have been conducted to date to identify potential markers for total mortality after diagnosis of breast cancer. Here, we report the identification of two singlenucleotide polymorphisms (SNP) associated with total mortality from a two-stage GWAS conducted among 6,110 Shanghai-resident Chinese women with tumor-node-metastasis (TNM) stage I to IV breast cancer. The discovery stage included 1,950 patients and evaluated 613,031 common SNPs. The top 49 associations were evaluated in an independent replication stage of 4,160 Shanghai patients with breast cancer. A consistent and highly significant association with total mortality was documented for SNPs rs3784099 and rs9934948. SNP rs3784099, located in the RAD51L1 gene, was associated with total morality in both the discovery stage (P = 1.44 × 10 -8) and replication stage (P = 0.06; P-combined = 1.17 × 10 -7). Adjusted HRs for total mortality were 1.41 [95% confidence interval (CI), 1.18-1.68] for the AG genotype and 2.64 (95% CI, 1.74-4.03) for the AA genotype, when compared with the GG genotype. The variant C allele of rs9934948, located on chromosome 16, was associated with a similarly elevated risk of total mortality (P-combined = 5.75 × 10 -6). We also observed this association among 1,145 patients with breast cancer of European ancestry from the Nurses' Health Study (NHS; P = 0.006); the association was highly significant in a combined analysis of NHS and Chinese data (P = 1.39 × 10 -7). Similar associations were observed for these two SNPs with breast cancer-specific mortality. This study provides strong evidence suggesting that the RAD51L1 gene and a chromosome 16 locus influence breast cancer prognosis. ©2012 AACR.",
        "keywords": [
            "dna binding proteins",
            "genetic markers",
            "genome wide association study"
        ],
        "authors": [
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Chun Li",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wendy Y Chen",
                "org": "Brigham and Women's Hospital(Brigham and Women's Hospital),Boston,United States"
            },
            {
                "name": "Ryan J. Delahanty",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Jiarong Cheng",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Jiajun Shi",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Wen-Jing Wang",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Peter L. Kraft",
                "org": "Harvard School of Public Health(Harvard School of Public Health),Boston,United States"
            },
            {
                "name": "Yutang Gao -",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "Cancer Research",
        "year": 2012
    },
    "dICWJd9g": {
        "id": "dICWJd9g",
        "title": "Plasma carotenoids, tocopherols, retinol and breast cancer risk: results from the Shanghai Women Health Study (SWHS).",
        "abstract": "Evidence from some previous studies suggests that lipophilic antioxidants, particularly carotenoids, may reduce the risk of breast cancer. We prospectively investigated the associations of plasma levels of tocopherols, retinol, carotenoids with the risk of developing breast cancer among Chinese women. We conducted a study of 365 incident breast cancer cases and 726 individually matched controls nested within a large cohort study of women aged 40-70 years at baseline. We observed no associations between breast cancer risk and any of the tocopherols, retinol, and most carotenoids. However, high levels of plasma lycopene other than trans, 5- and 7-cis or trans alpha-cryptoxanthin were inversely associated with the risk of developing breast cancer. Our results do not support an overall protective effect of lipophilic antioxidants on breast cancer risk. The few inverse associations observed for subtype of carotenoids may need to be confirmed in future studies.",
        "keywords": [
            "breast cancer",
            "lipophilic antioxidants",
            "plasma",
            "risk",
            "risk factors",
            "china",
            "correlation",
            "carotenoids",
            "statistical analysis",
            "cohort studies",
            "cohort study"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "National Cancer Institute, NIH Department of Health and Human Services, Division of Cancer Epidemiology and Genetics Bethesda MD USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "National Cancer Institute, NIH Department of Health and Human Services, Division of Cancer Epidemiology and Genetics Bethesda MD USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Adrian A Franke",
                "org": "University of Hawaii Cancer Research Center of Hawaii 1236 Lauhala Street Honolulu HI 96813 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt University School of Medicine Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center Nashville TN USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2009
    },
    "F3fJlmGq": {
        "id": "F3fJlmGq",
        "title": "Occupational Lead Exposure and Associations with Selected Cancers: The Shanghai Men's and Women's Health Study Cohorts.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "linda m liao",
                "org": ""
            },
            {
                "name": "melissa c friesen",
                "org": ""
            },
            {
                "name": "y b xiang",
                "org": ""
            },
            {
                "name": "h cai",
                "org": ""
            },
            {
                "name": "d h koh",
                "org": ""
            },
            {
                "name": "b t ji",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "h l li",
                "org": ""
            },
            {
                "name": "s j locke",
                "org": ""
            },
            {
                "name": "nathaniel rothman",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "y t gao",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "mark p purdue",
                "org": ""
            }
        ],
        "venue": "Environmental Health Perspectives",
        "year": 2015
    },
    "cVO2eTVk": {
        "id": "cVO2eTVk",
        "title": "Ultimate Control over Hydrogen Bond Formation and Reaction Rates for Scalable Synthesis of Highly Crystalline vdW MOF Nanosheets with Large Aspect Ratio.",
        "abstract": "Large-scale synthesis of van der Waals (vdW) metal-organic framework (MOF) nanosheets with controlled crystallinity and interlayer coupling strength is one of the bottlenecks in 2D materials that has limited its successful transition to large-scale applications. Here, scalable synthesis of mBDC (m = Zn and Cu) 2D MOFs at large scales through a biphase method is demonstrated. The results show replacing water molecules with pyridine eliminates hydrogen bond formation at metal cluster sites. This prohibits tight coupling across adjacent MOF layers and sustains controllable 2D vdW MOF growth. It is further shown that control over the growth speed, crystallinity, and thickness can be achieved by addition of a controlled amount of triethylamine and formic acid to achieve highly crystalline vdW MOF nanosheets with extraordinarily high aspect ratio. The described synthesis route can easily be scaled up for large-scale production either by deposition onto desired substrates or in crystalline layered powder form. Owing to its large lateral size, vdW nature, and high crystallinity, it is possible to perform atomic force microscopy, Kelvin probe force microscopy, and Raman measurements on the 2D MOFs. The results not only establish their vibrational properties and layer-dependent responses but also show striking differences from other 2D inorganic materials.",
        "keywords": [
            "crystallinity",
            "hydrogen bonds",
            "reaction rate",
            "scalable synthesis",
            "vdW 2D MOFs"
        ],
        "authors": [
            {
                "name": "Yuxia Shen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bohan Shan",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Ying Qin",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Ashutosh Agarwal",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Dipesh B Trivedi",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Lei Liu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Houlong Zhuang",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Mu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "ADVANCED MATERIALS",
        "year": 2018
    },
    "DFOkR66L": {
        "id": "DFOkR66L",
        "title": "Lysophosphatidic acid and ischemic heart disease",
        "abstract": "Lysophosphatidic acid(LPA) is a potent bioactive lipid that has multiple specific effects on vessel wall cells,blood cells,cardiac myocytes and cardiac fibroblasts.Activated platelets are the primary source of LPA in circulation,which in turn stimulate platelet aggregation.It has shown that LPA can promote the formation of atherosclerosis and thrombus under certain conditions that might aggravate cardiovascular diseases,especially ischemic heart disease.LPA can enhance endothelial permeability and cause barrier dysfunction in the early phase of coronary atherosclerosis,as well as in the late phase trigger platlet activation and lead to intra-arterial thrombus formation upon rupture of the atherosclerotic plaque,finally cause myocardial ischemia and infarction.Furthermore,LPA can stimulate cardiac myocyte hypertrophy and fibroblasts proliferation,which aggravate myocardial hypertrophy after infarction.So,LPA plays an important role in the development of ischemic heart disease.",
        "keywords": [
            "Atherosclerosis",
            "Myocardial hypertrophy",
            "Ischemic heart disease",
            "Myocardial infarction",
            "Lysophosphatidic acid"
        ],
        "authors": [
            {
                "name": "XIU Chun-ying",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "hJ0DiFui": {
        "id": "hJ0DiFui",
        "title": "Prospective study of blood metabolites associated with colorectal cancer risk.",
        "abstract": "Few prospective studies, and none in Asians, have systematically evaluated the relationship between blood metabolites and colorectal cancer risk. We conducted a nested case-control study to search for risk-associated metabolite biomarkers for colorectal cancer in an Asian population using blood samples collected prior to cancer diagnosis. Conditional logistic regression was performed to assess associations of metabolites with cancer risk. In the current study, we included 250 incident cases with colorectal cancer and individually matched controls nested within two prospective Shanghai cohorts. We found 35 metabolites associated with risk of colorectal cancer after adjusting for multiple comparisons. Among them, 12 metabolites were glycerophospholipids including nine associated with reduced risk of colorectal cancer and three with increased risk [odds ratios (ORs) per standard deviation (SD) increase of transformed metabolites: 0.31 to 1.98; p values: 0.002 to 1.25 × 10 ]. The other 23 metabolites associated with colorectal cancer risk included nine lipids other than glycerophospholipid, seven aromatic compounds, five organic acids, and four other organic compounds. After mutual adjustment, nine metabolites remained statistically significant for colorectal cancer. Together, these independently associated metabolites can separate cancer cases from controls with an area under the curve of 0.76 for colorectal cancer. We have identified that dysregulation of glycerophospholipids may contribute to risk of colorectal cancer. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "Metabolomics",
            "biomarkers",
            "colorectal cancer",
            "nested case-control study"
        ],
        "authors": [
            {
                "name": "Xiang Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Nathaniel Rothman",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20850, USA."
            },
            {
                "name": "Danxia Yu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Hong-Lan Li",
                "org": "SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Xiao Ma",
                "org": "SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Qing Lan",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20850, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Wei Jia",
                "org": "Center for Translational Medicine, and Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            }
        ],
        "venue": "International journal of cancer",
        "year": 2018
    },
    "Kb9QP7tp": {
        "id": "Kb9QP7tp",
        "title": "The Combination of High Intensity Focused Ultrasound and Microbubble Contrast Agent Decreased the Enzymatic Activity of Echinococcus granulosus Protoscolices",
        "abstract": "To investigate the effects of a combination of high intensity focused ultrasound (HIFU) and microbubble contrast agent (MBCA) on the enzymatic activities of Echinococcus granulosus protoscolices in vitro,the E.granulosus protoscolices were isolated from hydatid cysts in sample sheep liver.The protoscolices suspension was mixed with a MBCA in volume proportions of 1:80,and exposed the suspension to HIFU at a dose of 50 W acoustic powers for 30 seconds.The HIFU treated protoscolices were smeared onto glass slides for enzymatic activities localization.The activities of adenosine triphosphate (ATPase),glucose-6-phosphatase (G-6-P) and succinate dehydrogenase (SDH) in the HIFU treated protoscolices were determinated by the histochemical staining methods for these enzymes.It was found that the activities of ATPase and SDH of protoscolices decreased more obviously in the combination of HIFU and MBCA than that of the HIFU alone,and activities of G-6-P also decreased partially in the protoscolices treated with HIFU combination above mentioned.The results suggested that the inhibitory effects of HIFU on the enzymatic activities of ATPase,G-6-P and SDH in E.granulosus protoscolices could be enhanced by adding a microbubble contrast agent to hydatid fluids,which might enhance the protoscolicidal effect of HIFU to E.granulosus protoscolices.",
        "keywords": [
            "hydatid",
            "adenosine triphosphatase",
            "glucose-6-phosphatase",
            "succinate dehydrogenase",
            "high intensity focused ultrasound",
            "protoscolex",
            "microbubble contrast agent"
        ],
        "authors": [
            {
                "name": "KONG Jing",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "YE Bin",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecular Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecular Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "HAN Xiu-min",
                "org": "Qinghai Institute for Endemic Disease Prevention and Control,Xining ,China"
            },
            {
                "name": "YANG Yong-hai",
                "org": "Qinghai Institute for Endemic Disease Prevention and Control,Xining ,China"
            },
            {
                "name": "LI Fa-qi",
                "org": "Institute of Ultrasound Engineering in Medicine,Chongqing Medical University,Chongqing ,China"
            }
        ],
        "venue": "Sichuan Journal of Zoology",
        "year": 2013
    },
    "30jOrk1c": {
        "id": "30jOrk1c",
        "title": "Influence of Pioglitazone on the Expression of Connective Tissue Growth Factor on Aorta in Hyperlipidemia Rats",
        "abstract": "Objective:To investigate the influence of pioglitazone on the expression of connective tissue growth factor(CTGF) on aortic in hyperlipidemia rats.Method:26 male SD rats were randomly divided into normal diet control group(n=9) and high-fat diet group(n=17),sub-cages,high-fat diet group was fed with hypercholesterol diet for 12 weeks,then the serum lipid level was measured in the all rats,and to know whether the model of rats with hyperlipidemia was constructed by feeding hypercholesterol diet,then the model rats were randomly divided into model group(n= 8) and pioglitazone group(n=9).From 13 weeks by intragastric administration,pioglitazone group rats were given pioglitazone(10mg/kg/d) for four weeks,the rest of two groups with normal saline irrigation for 4 weeks,then the serum lipid levels of all rats were measured and the aorta was taken for pathologic analysis(including optical microscopy,electron microscopy).The expression of CTGF was detected by immunohistochemical method and analyzed with Image-pro-plus software1.Results:After 12 weeks of feeding,compared with control group,the high-fat diet group showed significantly higher levels of total cholesterol(TC),triglyceride(TG) and low-density lipoprotein cholesterol(LDL-C)(P<0.01),indicated that successful modeling.Serum TC,TG levels of pioglitazone group were significantly lower than the model(P<0.01),aortic CTGF expression was also significantly reduced(P<0.01).Under light microscope,endothelial cells of pioglitazone group occasionally fall off,a small amount of subintimal foam cells,smooth muscle cells with mild hyperplasia,under electron microscope,within the cortex of rat vascular neat,occasionally mitochondrial swelling,smooth muscle cells were occasionally mitochondrial swelling and foamy change.Conclusion:The expression of CTGF increasing on the aorta of hyperlipidemia rats involved in vascular intimal injury.Pioglitazone intervention can reduce aortic CTGF expression,reduced aortic intimal injury,and has a protective effect on atherosclerosis.",
        "keywords": [
            "Atherosclerosis",
            "Pioglitazone",
            "Connective tissue growth factor",
            "Hyperlipidemia"
        ],
        "authors": [
            {
                "name": "Liu Chunli",
                "org": " School of Clincal Medicine,Southern Medical University,Nanjing "
            },
            {
                "name": "Shang Wei",
                "org": " School of Clincal Medicine,Southern Medical University,Nanjing "
            },
            {
                "name": "Cai Hui",
                "org": " School of Clincal Medicine,Southern Medical University,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2012
    },
    "5Ur2F4gP": {
        "id": "5Ur2F4gP",
        "title": "Abstract 626: Dietary glycemic load, glycemic index and risk of primary liver cancer: Results from the Shanghai women's and men's health studies",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jing gao",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "b t ji",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "emily vogtmann",
                "org": ""
            },
            {
                "name": "h l li",
                "org": ""
            },
            {
                "name": "wei zhang",
                "org": ""
            },
            {
                "name": "y t gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "y b xiang",
                "org": ""
            },
            {
                "name": "w h chow",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "QsfywNnG": {
        "id": "QsfywNnG",
        "title": "Thinking about Several Questions of Integrated Western Medicine and Traditional Chinese Medicine",
        "abstract": "We thought that it was hard to integrated western medicine and traditional Chinese medicine from theoretical base,we could consider to found some breakthrough points from instrument, drug,diagnostic technique and others by thinking the questions: theoretical developmental models of TCM, cognition to the concept of \"Unity of nature and human\",cognition to the angles of life resources,patient and thinking modes.",
        "keywords": [
            "combination",
            "western medicine and traditional Chinese medicine",
            "methodology"
        ],
        "authors": [
            {
                "name": "ZHAO Chun-jiang",
                "org": " Nanjing Hospital of TCM of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": " Nanjing Hospital of TCM of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Western Journal of Traditional Chinese Medicine",
        "year": 2012
    },
    "TZaYlBON": {
        "id": "TZaYlBON",
        "title": "USE OF SUBSTITUTED PYRAZOLES FOR THE TREATMENT OF ALLERGIES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "g u yin",
                "org": ""
            },
            {
                "name": "lars karlsson",
                "org": ""
            },
            {
                "name": "steven p meduna",
                "org": ""
            },
            {
                "name": "barbara a pio",
                "org": ""
            },
            {
                "name": "siquan sun",
                "org": ""
            },
            {
                "name": "robin l thurmond",
                "org": ""
            },
            {
                "name": "jianmei wei",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "BFsjz0r5": {
        "id": "BFsjz0r5",
        "title": "The Effect of Curcumin on the Expression of Nuclear Factor κB in Synovium of Adjuvant Arthritis Rats",
        "abstract": "Objective:To explore the possible role of curcumin in rheumatoid arthritis(RA) by detecting the expression of nuclear factor κB(NF-κB),tumor necrosis tactor-α(TNF-α)and interleukin-1β(IL-1β) in the synovium of adjuvant arthritis(AA) rats.Methods:The experimental SD rat model AA was set up by intradermal injection of freund's complete adjuvant(FCA).The expressions of TNF-αand IL-1βin synovial fluid were detected by ELISA,the expression of NF-κB in synovium was detected by immunohistochemistry,after treatment with curcumin.Results:Compared with normal group,the expressions of TNF-αand IL-1βin synovial fluid and NF-κB in synovium were increased in control group.After drug treatment,there was no statistical difference in above indexes between normal group and triptolide group.Conclusion:Curcumin may take the protective role in RA by downregulating the expression of NF-κB in synovium.",
        "keywords": [
            "Rats",
            "Cytokine",
            "Curcumin",
            "Synovium",
            "Adjuvant arthritis",
            "NF-κB"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            },
            {
                "name": "ZHENG Zhao-ling",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            },
            {
                "name": "SHANG Wei",
                "org": ",et al Nanjing General Hospital of Nanjing Military Command,PLA%%#Nanjing %%#"
            }
        ],
        "venue": "Journal of Emergency in Traditional Chinese Medicine",
        "year": 2009
    },
    "uewiSLN7": {
        "id": "uewiSLN7",
        "title": "Obesity, age, and oxidative stress in middle-aged and older women.",
        "abstract": "Recent evidence suggests that urinary F(2)-isoprostanes (F(2)-IsoPs) are more accurate markers of oxidative stress than other available biomarkers. Most previous studies used unmetabolized F(2)-IsoPs as a biomarker. Few previous studies measured 15-F(2t)-IsoP-M, a metabolite of one of the most common F(2)-IsoPs, 15-F(2t)-IsoP. Unlike 15-F(2t)-IsoP, 15-F(2t)-IsoP-M is not subject to autoxidation and renal production. To our knowledge, no study has compared the associations of age and body mass index (BMI) with F(2)-IsoPs to those with 15-F(2t)-IsoP-M. Urinary levels of F(2)-IsoPs and 15-F(2t)-IsoP-M were measured using gas chromatography-mass spectrometry for 845 healthy women aged 40-70 years. Both F(2)-IsoPs and 15-F(2t)-IsoP-M were elevated among smokers. The level of 15-F(2t)-IsoP-M increased with age, particularly after menopause, and with BMI. In contrast, F(2)-IsoPs decreased with age, regardless of menopausal status, and was not related to BMI. The association of 15-F(2t)-IsoP-M with age or menopausal status did not differ by BMI category, and the association with BMI was also independent of age or menopausal status. 15-F(2t)-IsoP-M appears to be a valuable biomarker of oxidative stress in age-and obesity-related diseases. Antioxid. Redox Signal. 14, 2453-2460.",
        "keywords": [
            "obesity",
            "cross sectional studies"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20892 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Quiyin Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "NCI, Div Canc Epidemiol & Genet, US Dept HHS, NIH, Bethesda, MD 20892 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Xinqing Deng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Martha J Shrubsole",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Harvey Murff",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Ginger Milne",
                "org": "Vanderbilt Univ, Sch Med, Div Clin Pharmacol, Dept Med & Pharmacol, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "ANTIOXIDANTS & REDOX SIGNALING",
        "year": 2011
    },
    "pE5YEs3i": {
        "id": "pE5YEs3i",
        "title": "Clinical Study of Panax Notoginseng Saponins for Improving Symptom of Rheumatoid Arthritis and Correlative Indexes",
        "abstract": "Objective:To observe the effect of improving symptom of joint for combination therapy of Panax notoginseng saponins(PNS)and methotrexate(MTX)and sulfasalazine(SASP)in patients with active rheumatoid arthritis(RA).Method:Sixty-three RA patients were randomized into therapy group(PNS+MTX+SASP,n=32)and control group(MTX+SASP,n=31).Painful joint index,tender joint index,swollen joint index,erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),rheumatoid factor(RF)and platelet were observed.Result:Compared with the control group,the PNS group had a superior improvedment in the painful joint index,tender joint index,swollen joint index,ESR and CRP(P<0.05) after 20-day treatment.Conclusion:Combination therapy of PNS,MTX and SASP is effective for improving symptom of joint in patients with active RA in the near future.",
        "keywords": [
            "Panax Notoginseng Saponins",
            "Rheumatoid Arthritis"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Nanjing General Hospital of Nanjing Command,Nanjing Jiangsu,,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Nanjing General Hospital of Nanjing Command,Nanjing Jiangsu,,China"
            },
            {
                "name": "HU Bing",
                "org": "Nanjing General Hospital of Nanjing Command,Nanjing Jiangsu,,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of Nanjing Command,Nanjing Jiangsu,,China"
            }
        ],
        "venue": "Journal of Yunnan University of Traditional Chinese Medicine",
        "year": 2006
    },
    "kIJv6Iqd": {
        "id": "kIJv6Iqd",
        "title": "Researched on the characteristics of self-excited induction generator",
        "abstract": "Micro-hydro as a new energy technology, has good prospects for development.On some occasions which don't control, the generator usually choose self-excited induction generator.The paper presents a method which the asynchronous motor can instead of the induction generator, and calculate compensation capacitance of the self-excited induction generator. Finally,this paper verified by experiments, which the changes of the output voltage and frequency and the changes of harmonic by changing the resistive load, when the asynchronous generator open-loop runs. The results show that,this method has feasibility and validity.",
        "keywords": [
            "Asynchronous motor",
            "Compensation capacitor",
            "Resistive load"
        ],
        "authors": [
            {
                "name": "wei min chen",
                "org": "China Jiliang Univ, Coll Mech & Elect Engn, Hangzhou 310018, Peoples R China"
            },
            {
                "name": "de zhi qi",
                "org": "China Jiliang Univ, Coll Mech & Elect Engn, Hangzhou 310018, Peoples R China"
            },
            {
                "name": "nan xie",
                "org": "Zhejiang Conservan & Hydropower Coll, Dept Comp & Informat Engn, Hangzhou 310018, Peoples R China"
            },
            {
                "name": "hui cai",
                "org": "China Jiliang Univ, Coll Mech & Elect Engn, Hangzhou 310018, Peoples R China"
            }
        ],
        "venue": "Advanced Materials Research",
        "year": 2014
    },
    "CbsHgRSr": {
        "id": "CbsHgRSr",
        "title": "Voltage sensitivity analysis based bus voltage regulation in transmission systems with UPFC series converter.",
        "abstract": "For a unified power flow controller (UPFC) operated in constant power-flow control mode, a novel control scheme of bus voltage regulation is presented. The voltage magnitudes of the ac buses are monitored in real-time operation and are controlled within their limits by the adjustment of the reactive power setting of the series converter. Firstly, the sensitivity of the voltage magnitudes of ac buses to the adjustment the reactive power setting of the series converter is deduced. Secondly, the control scheme of the bus voltage regulation is developed, which adjusts the reactive power setting of the series converter intelligently when the bus voltage limits are violated. Otherwise, the reactive power setting is kept at the value given by the control center. The validity of the proposed control scheme and the voltage sensitivity analysis is proved by the case study in IEEE 39-bus system. The case study also indicates that the proposed control scheme is still valid with a 0.15 second time delay, which further confirms the feasibility of the proposed control scheme in practical engineering.",
        "keywords": "",
        "authors": [
            {
                "name": "Pengcheng Song",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Chenxi Luo",
                "org": "Department of Electrical Engineering, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, China"
            }
        ],
        "venue": "IECON",
        "year": 2017
    },
    "x7cQHzam": {
        "id": "x7cQHzam",
        "title": "Post-diagnosis Cruciferous Vegetable Consumption and Breast Cancer Outcomes: a Report from the After Breast Cancer Pooling Project",
        "abstract": "Cruciferous vegetables are a major source of glucosinolate-derived bioactive compounds such as isothiocyanates, which have been shown in animal and in vitro studies to inhibit cancer growth and progression. Few studies have investigated cruciferous vegetable intake after diagnosis and breast cancer outcomes. Using data from the After Breast Cancer Pooling Project, which includes prospective data from U. S. and Chinese breast cancer survivors, we evaluated the association of cruciferous vegetables with breast cancer outcomes. Analyses included 11,390 women diagnosed with stage I-III invasive breast cancer (1990-2006) from four cohorts. Cruciferous vegetable intake (g/day) was assessed using food frequency questionnaires (mean of 22 months postdiagnosis). Study heterogeneity was evaluated by the Q statistic; hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using delayed-entry Cox regression models stratified by study. After a median follow-up of 9.0 years, 1,725 deaths and 1,421 recurrences were documented. In pooled analyses using study-specific quartiles, cruciferous vegetable intake was not associated with breast cancer outcomes, adjusting for known clinical prognostic factors and selected lifestyle factors. HRs (95% CIs) by increasing quartiles (reference = lowest quartile) were 1.08 (0.93-1.25), 1.01 (0.87-1.18), and 1.10 (0.95-1.28) for recurrence (P-trend = 0.34) and 1.01 (0.88-1.15), 0.97 (0.84-1.11), and 0.99 (0.86-1.13) for total mortality (P-trend = 0.84). No associations were observed for subgroups defined by estrogen receptor status, stage, or tamoxifen therapy. Cruciferous vegetable intake at approximately two years after diagnosis was not associated with recurrence or mortality. Our results do not support an association between postdiagnosis cruciferous vegetable intake and breast cancer outcomes. (C) 2013 AACR.",
        "keywords": [],
        "authors": [
            {
                "name": "sarah nechuta",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "bette j caan",
                "org": "Kaiser Permanente No Calif, Div Res, Oakland, CA USA"
            },
            {
                "name": "w y chen",
                "org": "Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Div Network Med,Dept Med, Boston, MA 02115 USA"
            },
            {
                "name": "marilyn l kwan",
                "org": "Kaiser Permanente No Calif, Div Res, Oakland, CA USA"
            },
            {
                "name": "wei lu",
                "org": "Shanghai Ctr Dis Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "hui cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "elizabeth m poole",
                "org": "Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Div Network Med,Dept Med, Boston, MA 02115 USA"
            },
            {
                "name": "shirley w flatt",
                "org": "Univ Calif San Diego, Moores UCSD Canc Ctr, Canc Prevent & Control Program, San Diego, CA 92103 USA"
            },
            {
                "name": "wei zheng",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "john p pierce",
                "org": "Univ Calif San Diego, Moores UCSD Canc Ctr, Canc Prevent & Control Program, San Diego, CA 92103 USA"
            },
            {
                "name": "xiaoou shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2013
    },
    "9pMCbAgP": {
        "id": "9pMCbAgP",
        "title": "Association of BMI, smoking and alcohol with multiple myeloma mortality in Asians: a pooled analysis of more than 800,000 participants in the Asia Cohort Consortium.",
        "abstract": "Background: To date, few epidemiologic studies have been conducted to elucidate lifestyle-related risk factors for multiple myeloma in Asia. We investigated the association of body mass index (BMI), smoking, and alcohol intake with the risk of multiple myeloma mortality through a pooled analysis of more than 800,000 participants in the Asia Cohort Consortium. Methods: The analysis included 805,309 participants contributing 10,221,623 person-years of accumulated follow-up across Asia Cohort Consortium cohorts. HRs and 95% confidence intervals (95% CI) for the association between BMI, smoking, and alcohol at baseline and the risk of multiple myeloma mortalitywere assessed using aCox proportional hazardsmodel with shared frailty. Results: We observed a statistically significant dose-dependent association between BMI categories and the risk of multiple myeloma mortality (<18.5 kg/m(2): HR = 0.80,95% CI: 0.52-1.24; 18.5-24.9 kg/m(2): reference; 25.0-29.9 kg/m(2): HR = 1.17, 95% CI: 0.94-1.47; >= 30 kg/m(2): HR = 1.61, 95% CI: 0.99-2.64, P-trend = 0.014). By sex, this association was more apparent in women than in men (P for heterogeneity between sexes = 0.150). We observed no significant associations between smoking or alcohol consumption and risk of multiple myeloma mortality. Conclusions: This study showed that excess body mass is associated with an increased risk of multiple myeloma mortality among Asian populations. In contrast, our results do not support an association between smoking or alcohol consumption and the risk of multiple myeloma mortality in Asian populations. Impact: This study provides important evidence on the association of BMI, smoking, and alcohol with the risk of multiple myeloma mortality in Asian populations.",
        "keywords": "",
        "authors": [
            {
                "name": "Tomotaka Ugai",
                "org": "Aichi Canc Ctr, Dept Prevent Med, Div Canc Epidemiol & Prevent, Res Inst, Nagoya, Aichi, Japan"
            },
            {
                "name": "Hidemi Ito",
                "org": "Aichi Canc Ctr, Dept Prevent Med, Div Canc Informat & Control, Res Inst, Nagoya, Aichi, Japan"
            },
            {
                "name": "Isao Oze",
                "org": "Aichi Canc Ctr, Dept Prevent Med, Div Canc Epidemiol & Prevent, Res Inst, Nagoya, Aichi, Japan"
            },
            {
                "name": "Eiko Saito",
                "org": "Natl Canc Ctr, Integrat Ctr Canc Control & Informat Serv, Div Canc Stat, Tokyo, Japan"
            },
            {
                "name": "Md Shafiur Rahman",
                "org": "Univ Tokyo, Grad Sch Med, Dept Global Hlth Policy, Tokyo, Japan"
            },
            {
                "name": "Paolo Boffetta",
                "org": "Icahn Sch Med Mt Sinai, New York, NY 10029 USA"
            },
            {
                "name": "Prakash C Gupta",
                "org": "Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, Maharashtra, India"
            },
            {
                "name": "Norie Sawada",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Akiko Tamakoshi",
                "org": "Hokkaido Univ, Dept Publ Hlth, Grad Sch Med, Sapporo, Hokkaido, Japan"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "Woon-Puay Koh",
                "org": "Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore, Singapore"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Atsuko Sadakane",
                "org": "Radiat Effects Res Fdn, Dept Epidemiol, Hiroshima, Japan"
            },
            {
                "name": "Ichiro Tsuji",
                "org": "Tohoku Univ, Dept Publ Hlth & Forens Med, Div Epidemiol, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Sue K Park",
                "org": "Seoul Natl Univ, Dept Prevent Med, Coll Med, Seoul, South Korea"
            },
            {
                "name": "Chisato Nagata",
                "org": "Gifu Univ, Dept Epidemiol & Prevent Med, Grad Sch Med, Gifu, Japan"
            },
            {
                "name": "San-Lin You",
                "org": "Fu Jen Catholic Univ, Sch Med, New Taipei, Taiwan"
            },
            {
                "name": "Mangesh S Pednekar",
                "org": "Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, Maharashtra, India"
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "Jian-Min Yuan",
                "org": "Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Kotaro Ozasa",
                "org": "Radiat Effects Res Fdn, Dept Epidemiol, Hiroshima, Japan"
            },
            {
                "name": "Yasutake Tomata",
                "org": "Tohoku Univ, Dept Publ Hlth & Forens Med, Div Epidemiol, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Seiki Kanemura",
                "org": "Tohoku Univ, Dept Publ Hlth & Forens Med, Div Epidemiol, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Yumi Sugawara",
                "org": "Tohoku Univ, Dept Publ Hlth & Forens Med, Div Epidemiol, Grad Sch Med, Sendai, Miyagi, Japan"
            },
            {
                "name": "Keiko Wada",
                "org": "Gifu Univ, Dept Epidemiol & Prevent Med, Grad Sch Med, Gifu, Japan"
            },
            {
                "name": "Chien-Jen Chen",
                "org": "Acad Sinica, Genom Res Ctr, Taipei, Taiwan"
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Seoul Natl Univ, Dept Prevent Med, Seoul, South Korea"
            },
            {
                "name": "Kee Seng Chia",
                "org": "Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore"
            },
            {
                "name": "Habibul Ahsan",
                "org": "Univ Chicago, Dept Publ Hlth Sci, Chicago, IL 60637 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Epidemiol Ctr, Vanderbilt Ingram Canc Ctr, Div Epidemiol, Nashville, TN USA"
            },
            {
                "name": "Manami Inoue",
                "org": "Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan"
            },
            {
                "name": "Daehee Kang",
                "org": "Seoul Natl Univ, Dept Prevent Med, Coll Med, Seoul, South Korea"
            },
            {
                "name": "John D Potter",
                "org": "Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA"
            },
            {
                "name": "Keitaro Matsuo",
                "org": "Aichi Canc Ctr, Dept Prevent Med, Div Canc Epidemiol & Prevent, Res Inst, Nagoya, Aichi, Japan"
            }
        ],
        "venue": "CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION",
        "year": 2019
    },
    "oqoRmftL": {
        "id": "oqoRmftL",
        "title": "Effects of Tetramethylpyrazine on Proliferation and Collagen Synthesis of Cardiac Fibroblast",
        "abstract": "Objective To investigate the effects of tetramethylpyrazine (TMP) on the proliferation and collagen synthesis of cardiac fibroblasts (CF) in vitro culture. Methods The isolated and cultured neonatal SD rats were used as experimental models, CF proliferation was measured by MTT assay and collagen synthesis was measured by hydroxyproline alkaline hydrolysis assay. Results A490 value of CF decreased with the elevation of TMP concentration. The secretion of collagen decreased with the elevation of TMP concentration and action time. Conclusion TMP could decrease the proliferation and collagen synthesis of rat CF.",
        "keywords": [
            "cardiac fibroblast",
            "proliferation",
            "tetramethylpyrazine",
            "collagen synthesis"
        ],
        "authors": [
            {
                "name": "XIU Chun-ying",
                "org": " Fujian Academy of TCM and Pharmacy, Fuzhou, Fujian , China"
            },
            {
                "name": "CAI Hui",
                "org": " Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu , China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": " Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu , China"
            }
        ],
        "venue": "Journal of Fujian University of Traditional Chinese Medicine",
        "year": 2008
    },
    "UMWzBPSI": {
        "id": "UMWzBPSI",
        "title": "Prospective study of blood metabolites associated with colorectal cancer risk: Colorectal cancer risk associated blood metabolites",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiang Shu",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "SKLORG & Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"
            },
            {
                "name": "Nathaniel Rothman",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch; National Cancer Institute; Rockville MD"
            },
            {
                "name": "Danxia Yu",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Honglan Li",
                "org": "SKLORG & Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Xiao Ma",
                "org": "SKLORG & Department of Epidemiology; Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine; Shanghai China"
            },
            {
                "name": "Qing Lan",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch; National Cancer Institute; Rockville MD"
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Jia",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Wei Jia",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine; Nashville TN"
            }
        ],
        "venue": "International Journal of Cancer",
        "year": 2018
    },
    "2OmRAg0G": {
        "id": "2OmRAg0G",
        "title": "Time-varying effects of prognostic factors associated with long-term survival in breast cancer.",
        "abstract": "The impact of some prognostic factors on breast cancer survival has been shown to vary with time since diagnosis. However, this phenomenon has not been evaluated in Asians. In the present study, 4886 patients were recruited from the Shanghai Breast Cancer Survival Study, a longitudinal study of patients diagnosed during 2002-2006, with a median follow-up time of 11.2 years. Cox model incorporating time-by-covariate interactions was used to describe the time-varying effects of prognostic factors related to overall survival and disease-free survival. Age >= 65 years showed a progressively negative effect on breast cancer prognosis over time, whereas tumour size >2cm had a lasting and constant impact. Age significantly modified the effects of the tumour grade, nodal status and oestrogen receptor (ER) status on breast cancer survival. The detrimental effect of poorly differentiated tumours was time limited and more obvious in patients aged 45-54 years. Having >= 4 positive lymph nodes had a persistent and negative impact on prognosis, although it attenuated in later years; the phenomenon was more prominent in the 55-64-year age group. ER-positive status was protective in the first 3 years after diagnosis but was related to a higher risk of recurrence in later years; the time-point when ER-positive status turned into a risk factor was earlier in younger patients. These results suggest that older age, positive lymph node status, larger tumour size and ER-positive status are responsible for late death or recurrence in Asian breast cancer survivors. Extended endocrine therapy should be given earlier in younger ER-positive patients.",
        "keywords": [
            "breast cancer",
            "long-term survival",
            "prognostic factor",
            "hormone receptor"
        ],
        "authors": [
            {
                "name": "Minlu Zhang",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Peng Peng",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med, Nashville, TN 37212 USA"
            },
            {
                "name": "Guoyou Qin",
                "org": "Fudan Univ, Sch Publ Hlth, Dept Biostat, Shanghai, Peoples R China"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med, Nashville, TN 37212 USA"
            },
            {
                "name": "Pingping Bao",
                "org": "Shanghai Municipal Ctr Dis Control & Prevent, Dept Canc Control & Prevent, Shanghai, Peoples R China"
            }
        ],
        "venue": "ENDOCRINE-RELATED CANCER",
        "year": 2018
    },
    "s1RgvenX": {
        "id": "s1RgvenX",
        "title": "Dietary polyunsaturated fatty acids and breast cancer risk in Chinese women: A prospective cohort study",
        "abstract": "Breast cancer is the most common cancer in women. Controversy exists regarding the role of dietary fat in breast cancer etiology. We investigated the association of dietary polyunsaturated fatty acids (PUFAs) and the ratio of n-6 PUFAs to marine-derived n-3 PUFAs with breast cancer risk in the Shanghai Women's Health Study, a prospective cohort study including 72,571 cancer-free participants at baseline. Dietary fatty acid intake was determined using food frequency questionnaires. We used Cox proportional hazards analysis to estimate the relative risks (RRs) and 95% confidence intervals (CIs) for the association of breast cancer risk with dietary fatty acids consumption. In 583,998 person-years of follow-up, we identified 712 breast cancer cases. We found no association of breast cancer risk to dietary intake of linoleic acid, arachidonic acid, α-linolenic acid or marine-derived n-3 PUFA. We found a statistically significant interaction between n-6 PUFA intake, marine-derived n-3 PUFA intake and breast cancer risk (p = 0.008). Women with lower intake (the lowest tertile) of marine-derived n-3 PUFA and higher intake (the highest tertile) of n-6 PUFA had an increase risk for breast cancer (RR = 2.06; 95% CI = 1.27-3.34) compared to women with higher intake (the highest tertile) of marine-derived n-3 PUFAs and lower intake (the lowest tertile) of n-6 PUFAs after adjusting for potential confounders. The relative amounts of n-6 PUFA to marine-derived n-3 PUFAs may be more important for breast cancer risk than individual dietary amounts of these fatty acids. Copyright © 2010 UICC.",
        "keywords": [
            "breast neoplasms",
            "cohort studies",
            "fatty acids",
            "risk factors",
            "unsaturated",
            "prospective studies",
            "questionnaires",
            "china"
        ],
        "authors": [
            {
                "name": "Harvey J. Murff",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiauyan Wu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wanqing Wen",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yutang Gao -",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "International journal of cancer. Journal international du cancer",
        "year": 2011
    },
    "e6NnYfmK": {
        "id": "e6NnYfmK",
        "title": "Theory and application of k-mask based hyper-connectivity",
        "abstract": "In order to fuse efficiently the multi-channel information of the target and improve the performance of the filter, a new class of k-mask based hyper-connectivity was proposed. The connectivity mask image and the reconstruct mask image were obtained from the different channel informations and restraint conditions. According to the area information by which the connectivity mask image intersects the reconstruct mask image, the connected components in the reconstruct mask image were relabeled to form the new connection space by selection and aggregation. From the definition of the hyper-connectivity class, k-mask based hyper-connected open operator and reconstruct operator were designed and applied in labeling the character region and extracting the major path of the remote sensing image. Experiment results illustrated that the filter performance of the traditional open operator and reconstruction operator was improved significantly by flexible selection of the connectivity mask image and fusion of the image multi-gradient information, color information and multi-channel information.",
        "keywords": [
            "Computer application",
            "Connected operator",
            "Hyper-connectivity",
            "Image segmentation",
            "Reconstruction operator"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Fujian Provincial Central Inspection Institute(Fujian Provincial Central Inspection Institute,Fujian Central Inst. of Inspection),Fuzhou,China"
            },
            {
                "name": "CAI Jin-hui",
                "org": "China Jiliang University(China Jiliang University ^),Hangzhou,China"
            },
            {
                "name": "ZHANG Guang-xin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "HOU Di-bo",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Jilin Daxue Xuebao (Gongxueban)/Journal of Jilin University (Engineering and Technology Edition)",
        "year": 2010
    },
    "r153zbX5": {
        "id": "r153zbX5",
        "title": "Protoscolicidal effect of high intensity focused ultrasound to hydatid cysts enhanced by superabsorbent resin in vitro",
        "abstract": "This study aimed to investigate the enhanced protoscolicidal effect of high intensity focused ultrasound(HIFU) combined with superabsorbent resin(SAR).The fresh hydatid cysts within the sheep liver measured at a diameter of 4.5-5 cm were randomly and equally divided into 6 groups: blank control group(group Ⅰ,no SAR in the cyst,no HIFU duration);SAR at a dose of half-saturation and saturation respectively(group Ⅱ and Ⅲ,no HIFU duration);HIFU experimental control groups(group Ⅳ,irradiated with HIFU only);the test groups(groupⅤ,treated with same HIFU power and SAR at a dose of half-saturation);saturation(group Ⅵ,the particles of SAR were injected into the cysts before the irradiation of HIFU).The irradiation power of experimental control groups was 200 w and the target was monitored by real-time B ultrasound.Just after the irradiation with HIFU,the temperature of hydatid fluid,cyst wall and the hepatic tissues around cysts were measured accordingly,and the instant death rates of protoscolices of hydatid fluid were determined by trypan blue exclusion assay.After HIFU irradiation,the temperatures of cyst wall,hydatid fluids and the hepatic tissues around cysts increased respectively.There were significant differences between the HIFU irradiation experimental groups and the control groups(P<0.05).In the HIFU treated group with SAR at a dose of half-saturation,the average temperature of cyst wall,cyst fluid,and adjacent hepatic tissues around cysts was(49±0.87)℃,(38.9±1.02)℃,and(34.5±0.88)℃,respectively.But in the HIFU treated group with SAR at a dose of saturation,the average temperature of above mentioned locations was(55±0.81)℃,(44.6±1.82)℃,and(37.88±0.67)℃,respectively.The death rate from Ⅰ to Ⅵ group was 22.94%,23.11%,24.43%,55.28%,63.4%,and 74.2%,respectively(P<0.05).It'S suggested that the combination of SAR and HIFU could increase the temperatures of the cyst wall and cyst fluid compared to those treated with HIFU only,so as to enhance the protoscolicidal effect of HIFU to the protoscolices in cyst fluid.",
        "keywords": [
            "hydatid",
            "high intensity focused ultrasound",
            "superabsorbent resin"
        ],
        "authors": [
            {
                "name": "ZHANG Jing",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecular Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "YE Bin",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecular Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathogenic Biology,Chongqing Medical University,Chongqing ,China;Research Center for Molecular Medicine and Tumor,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "ZHANG Cheng-wu",
                "org": "Department of Oncology,the Affiliated Hospital of Qinghai University,Qinghai ,China"
            },
            {
                "name": "ZHAO Yi-feng",
                "org": "Department of Oncology,the Affiliated Hospital of Qinghai University,Qinghai ,China"
            },
            {
                "name": "HAN Xiu-min",
                "org": ""
            },
            {
                "name": "LI Fa-qi",
                "org": "State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology,Chongqing ,China"
            },
            {
                "name": "WANG Qi",
                "org": "State Key Laboratory of Ultrasound Engineering in Medicine Co-founded by Chongqing and the Ministry of Science and Technology,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Zoonoses",
        "year": 2013
    },
    "1nsYkWWE": {
        "id": "1nsYkWWE",
        "title": "ChemInform Abstract: Synthesis and Properties of Substituted CBI Analogues of CC‐1065 and the Duocarmycins Incorporating the 7‐Methoxy‐1,2,9,9a‐ tetrahydrocyclopropa(c)benz(e)indol‐4‐one (MCBI) Alkylation Subunit: Magnitude of Electronic Effects on the Functional Reactivity.",
        "abstract": "",
        "keywords": [
            "antibiotics"
        ],
        "authors": [
            {
                "name": "dale l boger",
                "org": "scripps research institute"
            },
            {
                "name": "jeffrey a mckie",
                "org": "scripps research institute"
            },
            {
                "name": "hui cai",
                "org": "scripps research institute"
            },
            {
                "name": "barbara cacciari",
                "org": "scripps research institute"
            },
            {
                "name": "pier giovanni baraldi",
                "org": "scripps research institute"
            }
        ],
        "venue": "Cheminform",
        "year": 1996
    },
    "H8Bs2Urp": {
        "id": "H8Bs2Urp",
        "title": "Body mass index and weight change in relation to triple-negative breast cancer survival",
        "abstract": "The aim of this study was to evaluate the influence of body mass index (BMI), weight change on triple-negative breast cancer (TNBC) prognosis in a population-based prospective cohort study. The current analysis included 518 participants diagnosed with TNBC in Shanghai Breast Cancer Survival Study. Weight at 1 year prior to cancer diagnosis, at diagnosis, and at 6, 18 and 36 months after cancer diagnosis and height at 6 months after cancer diagnosis were assessed. Disease-free survival (DFS) and overall survival (OS) were evaluated in relation to BMI and weight change using Cox proportional hazard models. Obesity (BMI ≥ 28.0 kg/m2) at 1-year pre-diagnosis was associated with higher risk of total mortality and recurrence/disease-specific mortality, with multivariate hazard ratios (HRs) of 1.79 (95 % CI 1.06–3.03) and 1.83 (95 % CI 1.05–3.21), respectively. The associations between BMI and TNBC prognosis attenuated over time from pre-diagnosis to post-diagnosis. Compared with stable weight (change within 5 %), weight loss ≥5 % at 18- or 36-month post-diagnosis was related with higher risk of total mortality and recurrence/disease-specific mortality. Respective multivariate HRs were 2.08 (95 % CI 1.25–3.46) and 1.42 (95 % CI 0.77–2.63) for OS, and 2.50 (95 % CI 1.45–4.30) and 2.17 (95 % CI 1.14–4.12) for DFS. However, the association of weight loss and OS/DFS attenuated after excluding patients whose weight was measured after recurrence. Weight gain ≥5 % at 18- or 36-month post-diagnosis was associated with a non-significant increased risk of death. The results showed that obesity pre-diagnosis and weight loss post-diagnosis was inversely associated with TNBC prognosis. Emphasis on maintaining stable weight after cancer diagnosis for TNBC patients may be considered.",
        "keywords": [
            "Triple-negative breast cancer",
            " Body mass index",
            " Weight change",
            " Survival outcomes",
            " Prognosis"
        ],
        "authors": [
            {
                "name": "Ping-Ping Bao",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "peng peng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "kai gu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "yinghao su",
                "org": "vanderbilt university"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            }
        ],
        "venue": "Cancer causes & control : CCC",
        "year": 2015
    },
    "ECROFRof": {
        "id": "ECROFRof",
        "title": "Extracellular Matrix Promotes Embryonic Stem Cell Differentiation Towards a Retinal Progenitor Fate",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jie gong",
                "org": "columbia university"
            },
            {
                "name": "mark a fields",
                "org": "columbia university"
            },
            {
                "name": "hui cai",
                "org": "columbia university"
            },
            {
                "name": "stephen h tsang",
                "org": "columbia university"
            },
            {
                "name": "lucian v del priore",
                "org": "columbia university"
            }
        ],
        "venue": "Investigative Ophthalmology & Visual Science",
        "year": 2011
    },
    "bgft9UJZ": {
        "id": "bgft9UJZ",
        "title": "Changes of the plasma endothelin in rats with pressure overload",
        "abstract": "Objective: To observe the effects of pressure overload on level of plasma endothelin,and study the possible mechanism of left ventricular remodeling.Methods: left ventricular mass index(LVMI) and plasma endothelin were measured in the rat models with myocardial hypertrophy of chronic heart failure and pressure overload by abdominal aortic constriction by radioimmunoassay.Results: LVMI in the model group was obviously higher than that of the sham group(P<0.01).The plasma endothelin levels in the model group were obviously higher than those of sham group(P<0.01).Conclusion: pressure overload by abdominal aortic constriction can induce left ventricular remodeling in chronic heart failure,the mechanism of left ventricular remodeling might be related to the upregulated endothelin levels in plasma.",
        "keywords": [
            "chronic heart failure",
            "endothelin",
            "pressure overload",
            "rats"
        ],
        "authors": [
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHANG Yong-wen",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Modern Medical Journal",
        "year": 2010
    },
    "VLb0OVP1": {
        "id": "VLb0OVP1",
        "title": "Unveiling the Cologne Opera's Ring",
        "abstract": "On the eve of the Cologne Opera's The Ring of the Nibelung in Shanghai,5 lectures were organized by the Shanghai Grand Theatre Arts Class to introduce the subject.Opera transcribes and publishes S of these lectures here.On July 17,Uwe Eric Laufenberg,Cologne Opera's director,explained the origins of The Ring and the Bayreuth Festival,the conflicts within the Wagner family,and a series of historical productions. On July 25,Dr.Joanna C.Lee played almost 20 leitmotifs during the lecture and gave the audience a music analysis lecture.Critic Liu Xuefeng discussed the story of the Ring from the perspective of its core theme:love.We also include an interview with a super Ring fan living in Melbourne who flies around the world to track down Ring productions—he's already bought his tickets for Shanghai.",
        "keywords": [],
        "authors": [
            {
                "name": "乌韦·埃里克·劳芬伯格",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "hQOwXpdY": {
        "id": "hQOwXpdY",
        "title": "Study on novel power controllable distributed connected-grid inverter",
        "abstract": "Distributed connected-grid generator becomes an important approach to utilize renewable energy. However, traditional distributed connected-grid inverter can't be controlled and still can not be accepted by Power Grid Company. On the basis of conventional connected-grid inverter, a novel connected-grid inverter controlled by center controller was designed, which gets separate dq current component by processing voltage of grid and given output power value from center controller, then couples dq current component and obtains inverter output reference current, finally injects current to load with close-loop current control system. Simulation results verify the validity and the feasibility of controlled inverter.",
        "keywords": [
            "power control",
            "renewable energy",
            "close-loop current control system",
            "dq current component",
            "distributed connected-grid generator",
            "power controllable distributed connected-grid inverter",
            "power grid company",
            "electric current control",
            "connected-grid control",
            "inverter output reference current",
            "power grids",
            "invertors",
            "inverter",
            "mechatronics",
            "grid generation",
            "process control",
            "control system",
            "renewable energy resource",
            "renewable energy resources"
        ],
        "authors": [
            {
                "name": "Weimin Chen",
                "org": "China Jiliang University(China Jiliang University ^),Hangzhou,China"
            },
            {
                "name": "Shuang Chen",
                "org": "China Jiliang University(China Jiliang University ^),Hangzhou,China"
            },
            {
                "name": "GuoCheng Chen",
                "org": "Shanghai University(Shanghai University),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "China Jiliang University(China Jiliang University ^),Hangzhou,China"
            }
        ],
        "venue": "Electrical and Control Engineering",
        "year": 2011
    },
    "ZBDyqVnu": {
        "id": "ZBDyqVnu",
        "title": "ERBB2 genetic polymorphism and breast cancer risk in Chinese women: a population-based case-control study.",
        "abstract": "A polymorphism at codon 655 (ATC/isoleucine to GTC/valine [Ile655Val], rs1801200) in the transmembrane domain-coding region of human ERBB2 gene has been previously evaluated for its association with breast cancer risk with mixed results. We evaluated this polymorphism\n in association with breast cancer in a group of women who participated in a large-scale, population-based, case-control study\n of breast cancer in Shanghai, China, followed by an in vitro analysis of the function of this polymorphism. Genomic DNA from\n 3,012 patients with breast cancer and 3,004 healthy controls was examined for the Ile655Val polymorphism using a TaqMan genotyping method. Adjusted odds ratios (OR) were derived from multiple logistic regression.\n In vitro analyses were carried out to examine whether the Ile655Val polymorphism affect ERBB2 expression and the activity of its downstream targets. Approximately 2% of study subjects carry the Val/Val genotype. Compared\n with women with the Ile/Ile (76%) genotype, women who had the Ile/Val (22%) or Val/Val genotype did not have an elevated risk\n of breast cancer. Stratified analyses by age and menopausal status revealed no apparent association with this polymorphism\n in any subgroups of women. In a serious of biochemical analyses, we found that the Ile655Val substitution did not alter ErbB2 and its downstream signaling molecule activity. These study results suggest that Ile655Val polymorphism of the ERBB2 gene do not alter its activity and may not be associated with increased breast cancer risk among Chinese women.",
        "keywords": [
            "breast cancer risk",
            "erbb2",
            "genetic polymorphism",
            "polymorphism",
            "genomic dna",
            "case control study",
            "transmembrane domain",
            "logistic regression",
            "adjusted odds ratio",
            "breast cancer"
        ],
        "authors": [
            {
                "name": "Shimian Qu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Lu",
                "org": "Chinese Center for Disease Control and Prevention(^ Chinese Center for Disease Control and Prevention),Beijing,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yinghao Su",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Shizhen Emily Wang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2008
    },
    "11Q8VK5W": {
        "id": "11Q8VK5W",
        "title": "Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.",
        "abstract": "Large-scale meta-analyses of genome-wide association studies (GWAS) have identified > 175 loci associated with fasting cholesterol levels, including total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG). With differences in linkage disequilibrium (LD) structure and allele frequencies between ancestry groups, studies in additional large samples may detect new associations. We conducted staged GWAS meta-analyses in up to 69,414 East Asian individuals from 24 studies with participants from Japan, the Philippines, Korea, China, Singapore, and Taiwan. These meta-analyses identified (P < 5 x 10(-8)) three novel loci associated with HDL-C near CD163-APOBEC1 (P = 7.4 x 10(-9)), NCOA2 (P = 1.6 x 10(-8)), and NID2-PTGDR (P = 4.2 x 10(-8)), and one novel locus associated with TG near WDR11-FGFR2 (P = 2.7 x 10(-10)). Conditional analyses identified a second signal near CD163-APOBEC1. We then combined results from the East Asian meta-analysis with association results from up to 187,365 European individuals from the Global Lipids Genetics Consortium in a trans-ancestry meta-analysis. This analysis identified (log(10)Bayes Factor a 6.1) eight additional novel lipid loci. Among the twelve total loci identified, the index variants at eight loci have demonstrated at least nominal significance with other metabolic traits in prior studies, and two loci exhibited coincident eQTLs (P < 1 x 10(-5)) in subcutaneous adipose tissue for BPTF and PDGFC. Taken together, these analyses identified multiple novel lipid loci, providing new potential therapeutic targets.",
        "keywords": "",
        "authors": [
            {
                "name": "Cassandra N Spracklen",
                "org": "University of North Carolina at Chapel Hill"
            },
            {
                "name": "Peng Chen",
                "org": ""
            },
            {
                "name": "Young Jin Kim",
                "org": ""
            },
            {
                "name": "Xu Wang",
                "org": "National University of Singapore"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University Medical Center"
            },
            {
                "name": "Shengxu Li",
                "org": "Tulane University"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt University Medical Center"
            },
            {
                "name": "Ying Wu",
                "org": "University of North Carolina at Chapel Hill"
            },
            {
                "name": "Ya Xing Wang",
                "org": "Capital Medical University"
            },
            {
                "name": "Fumihiko Takeuchi",
                "org": ""
            }
        ],
        "venue": "HUMAN MOLECULAR GENETICS",
        "year": 2017
    },
    "dy64wFft": {
        "id": "dy64wFft",
        "title": "Influence of Methotrexate on MyD88 protein expression of synovium in adjuvant-induced arthritis rats",
        "abstract": "Objective To investigate the change of protein of MyD88 in synovium of adjuvant-induced arthritis rats treated with Methotrexate(MTX),and also to study the possible mechanism of Methotrexate improving the synovium inflammation.Methods 30 SD rats were randomly assigned into control group(n=10)and adjuvant-induced group(n=20).After modeled,the rats in adjuvant-induced group were randomly assigned into model group(n=10)and Methotrexate group(n=10).After 4 weeks,HE staining was used to observe synovium pathological changes,IHC and Western blot were used to observe MyD88 expression,and ELISA was used to measure the expression of inflammation factor IL-1β.Results In the model group,compared to control group,pathological changes of synovium were significant and IL-1β expression improved markedly(P<0.001),while after treated with MTX,synovium pathological changes and IL-1β expression(P<0.001)both decreased.Meanwhile,MyD88 expression was higher in model group than in control group(P<0.001),and treated with MTX,MyD88 expression decreased(P<0.05).Conclusions The expression of MyD88 in synovium of adjuvant-induced rats increased.MTX decreased its expression and decreased the expression of IL-1β,improved the pathological progress.",
        "keywords": [
            "arthritis",
            "methotrexate",
            "IL-1β",
            "MyD88"
        ],
        "authors": [
            {
                "name": "MU Hui",
                "org": "School of Medicine,Second Military Medical University%%#Shanghai%%#,Jinling Hospital,Department of Integrated Traditional and Western Medicine,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "School of Medicine,Second Military Medical University%%#Shanghai%%#,Jinling Hospital,Department of Integrated Traditional and Western Medicine,Nanjing,Jiangsu ,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "School of Medicine,Second Military Medical University%%#Shanghai%%#,Jinling Hospital,Department of Integrated Traditional and Western Medicine,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2013
    },
    "gi1PoCxN": {
        "id": "gi1PoCxN",
        "title": "Dietary and lifestyle predictors of age at natural menopause and reproductive span in the Shanghai Women's Health Study.",
        "abstract": "Objective: Modifiable factors predicting the onset of menopause, a transition with important implications for women's health, have not been fully characterized. We evaluated the impact of dietary, lifestyle and reproductive factors on age at natural menopause and reproductive span in Chinese women. Design: Study participants were Chinese women aged 40 to 70 who experienced natural menopause and participated in a population-based, prospective study, the Shanghai Women's Health Study (N = 33,054). Dietary intake at the baseline survey was assessed by food-frequency questionnaire. Regression (P) coefficients, calculated by multivariable linear regression, were used to estimate the effects of dietary, lifestyle, and reproductive patterns on age at menopause and the number of reproductive years, adjusting for potential confounding factors. Results: Early menarche, younger age at first live birth, older age at last live birth, longer duration of breast-feeding, and higher parity were associated with longer reproductive years (P-trend < 0.01 for all). Higher body mass index at age 20, mid-life weight gain, and leisure-time physical activity during adolescence and adulthood predicted later menopause and longer reproductive span (P-trend < 0.01 for all). Total intake of calories, fruits, and protein was positively associated with later menopause (P-trend < 0.05 for all) and longer reproductive span (P-trend < 0.05), except for carbohydrates (P-trend = 0.06), and long-term tea consumption predicted longer reproductive span (P-trend = 0.03). Vegetable, fat, soy, and fiber intakes did not significantly affect reproductive span or age at menopause. Smoking was inversely assoicated with both early age at menopause and shorter reproductive span (P-trend < 0.01). Conclusions: In addition to reproductive factors, intake of fruits and protein, smoking, tea consumption, lifetime patterns of physical activity, and weight gain influenced the onset of menopause and/or reproductive span in Chinese women.",
        "keywords": [
            "age at onset of menopause",
            "dietary intake",
            "physical activity",
            "reproductive span",
            "smoking",
            "tea",
            "weight gain"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Asha Kallianpur",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37203 USA"
            }
        ],
        "venue": "MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY",
        "year": 2008
    },
    "n6wXO4NJ": {
        "id": "n6wXO4NJ",
        "title": "Fish, shellfish, and long-chain n-3 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women.",
        "abstract": "Background: Long-chain polyunsaturated n-3 (omega-3) fatty acids, found mainly in fish, have been postulated to reduce type 2 diabetes (T2D) risk. However, the role of long-chain n-3 fatty acids and fish intake in the development of T2D remains unresolved. Objective: We examined associations between fish, shellfish, and long-chain n-3 fatty acids and the risk of T2D in a middle-aged Chinese population. Design: This was a prospective population-based cohort study in 51,963 men and 64,193 women free of T2D, cardiovascular disease, and cancer at baseline with valid dietary information. Dietary intake, physical activity, and anthropometric measurements were collected. A Cox regression model was used to evaluate the association of fish, shellfish, and long-chain n-3 fatty acid (in g/d) with risk of T2D. Results: Fish, shellfish, and long-chain n-3 fatty acid intakes were inversely associated with T2D in women. The relative risks [RRs (95% CI)] for quintiles of fish intake were 1.00, 0.96 (0.86, 1.06), 0.84 (0.75, 0.94), 0.80 (0.71, 0.90), and 0.89 (0.78, 1.01) (P for trend = 0.003) and for shellfish were 1.00, 0.91 (0.82, 1.01), 0.79 (0.71, 0.89), 0.80 (0.71, 0.91), and 0.86 (0.76, 0.99) (P for trend = 0.006). In men, only the association between shellfish intake and T2D was significant. The RRs (95% CI) for quintiles of fish intake were 1.00, 0.92 (0.75, 1.13), 0.80 (0.65, 1.00), 0.89 (0.72, 1.11), and 0.94 (0.74, 1.17) (P for trend = 0.50) and for shellfish intake were 1.00, 0.93 (0.76, 1.12), 0.70 (0.56, 086), 0.66 (0.53, 0.82), and 0.82 (0.65, 1.02) (P for trend = 0.003). Conclusions: An inverse association between fish and shellfish intake and T2D in women was found. No evidence of a detrimental effect of fish intake in this population was observed. Am J Clin Nutr 2011;94:543-51.",
        "keywords": [],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "tom a elasy",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Fei Ye",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Yu Shyr",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF CLINICAL NUTRITION",
        "year": 2011
    },
    "0VgICpuf": {
        "id": "0VgICpuf",
        "title": "Dietary patterns and their correlates among middle-aged and elderly Chinese men: a report from the Shanghai Men's Health Study.",
        "abstract": "Dietary patterns, which reflect the complexity of food preference, lifestyle and socio-economic status, may play a major role in health and longevity. Understanding dietary patterns and their correlates is important to the research of diet and health relationships. In the Shanghai Men's Health Study (SMHS) a total of 61582 men aged 40-74 were recruited between 2002 and 2006. Their food intake over the previous year was collected using a validated FFQ. Study participants (75.6 %) reported little or no change in meat and vegetable intake in the 5 years prior to recruitment. Using the baseline data of the SMHS, we assessed dietary patterns, as well as their relationship with socio-demographic and lifestyle factors and with prevalence of some chronic diseases. Three major dietary patterns, fruit-, vegetable- and meat-based diets, were identified in our population. Consumption of the fruit diet appeared to be more common among men who were older and more physically active, had higher income, and lower waist-to-hip ratio (WHR), while this diet was less common among manual labourers. The meat- or vegetable-based diets were less common among elderly men and more common among men with higher WHR. Dietary patterns appeared to be associated with the presence of health conditions. In general, subjects with a chronic disease were more likely to have the vegetable-based diet and less likely to have the fruit- or meat-based diets. Future studies of diet and health in this population will need to carefully take into account these potential confounders.",
        "keywords": [
            "dietary patterns",
            "socio-econornic and lifestyle factors",
            "relationship",
            "factor analysis"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Wang Hong Xu",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            }
        ],
        "venue": "BRITISH JOURNAL OF NUTRITION",
        "year": 2007
    },
    "2sOemrbV": {
        "id": "2sOemrbV",
        "title": "Prospective metabolomics study identifies potential novel blood metabolites associated with pancreatic cancer risk.",
        "abstract": "Using a metabolomics approach, we systematically searched for circulating metabolite biomarkers for pancreatic cancer risk in a case-control study nested within two prospective Shanghai cohorts. Included in this study were 226 incident pancreatic cancer cases and their individually-matched controls. Untargeted mass spectrometry platforms were used to measure metabolites in blood samples collected prior to cancer diagnosis. Conditional logistic regression was performed to assess the associations of metabolites with pancreatic cancer risk. We identified 10 metabolites associated with pancreatic cancer, after accounting for multiple comparisons (the Benjamini-Hochberg false discovery rate < 0.05). The majority of the identified metabolites were glycerophospholipids (ORs per SD increase: 0.44 to 2.32; p values: 7.2 × 10 to 1.0 × 10 ), six of which were associated with decreased risk and one with increased risk. Additionally, levels of coumarin (OR = 1.96, p = 3.7 × 10 ) and picolinic acid (OR = 2.53, p = 5.0 × 10 ) were positively associated with pancreatic cancer risk, while tetracosanoic acid was inversely associated with risk (OR: 0.48, p = 7.16 × 10 ). Four metabolites remained statistically significant after mutual adjustment. This study provides novel evidence that the dysregulation of glycerophospholipids may play an important role in pancreatic cancer development. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "Metabolomics",
            "biomarkers",
            "nested case-control study",
            "pancreatic cancer"
        ],
        "authors": [
            {
                "name": "Xiang Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Danxia Yu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Hong-Lan Li",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Qing Lan",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20850, USA."
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            },
            {
                "name": "Xiao Ma",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Nathaniel Rothman",
                "org": "Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20850, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Wei Jia",
                "org": "Center for Translational Medicine, and Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA."
            }
        ],
        "venue": "International journal of cancer",
        "year": 2018
    },
    "kndRQzKe": {
        "id": "kndRQzKe",
        "title": "Valley-dependent Exciton Fine Structure and Autler-Townes Doublets from Berry Phases in Monolayer Molybdenum Diselenide",
        "abstract": "Author(s): Yong, Chaw-Keong; Utama, M Iqbal Bakti; Ong, Chin Shen; Cao, Ting; Regan, Emma C; Horng, Jason; Shen, Yuxia; Cai, Hui; Watanabe, Kenji; Taniguchi, Takashi; Tongay, Sefaattin; Deng, Hui; Zettl, Alex; Louie, Steven G; Wang, Feng | Abstract: The Berry phase of Bloch states can have profound effects on electron dynamics lead to novel transport phenomena, such as the anomalous Hall effect and the valley Hall effect. Recently, it was predicted that the Berry phase effect can also modify the exciton states in transition metal dichalcogenide monolayers, and lift the energy degeneracy of exciton states with opposite angular momentum through an effective valley-orbital coupling. Here, we report the first observation and control of the Berry-phase induced splitting of the 2p-exciton states in monolayer molybdenum diselenide using the intraexciton optical Stark spectroscopy. We observe the time-reversal-symmetric analog of the orbital Zeeman effect resulting from the valley-dependent Berry phase, which leads to energy difference of +14 (-14) meV between the $2p^+$ and $2p^-$ exciton states in +K (-K) valley, consistent with the ordering from our ab initio GW-BSE results. In addition, we show that the light-matter coupling between intraexciton states are remarkably strong, leading to prominent valley-dependent Autler-Townes doublet under resonant driving. Our study opens up new pathways to coherently manipulate the quantum states and excitonic excitation with infrared radiation in two-dimensional semiconductors.",
        "keywords": "",
        "authors": [
            {
                "name": "Chaw-Keong Yong",
                "org": ""
            },
            {
                "name": "M. Iqbal Bakti Utama",
                "org": ""
            },
            {
                "name": "Chin Shen Ong",
                "org": ""
            },
            {
                "name": "Ting Cao",
                "org": ""
            },
            {
                "name": "Emma C. Regan",
                "org": ""
            },
            {
                "name": "Jason Horng",
                "org": ""
            },
            {
                "name": "Yuxia Shen",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Kenji Watanabe",
                "org": ""
            },
            {
                "name": "Takashi Taniguchi",
                "org": ""
            },
            {
                "name": "Sefaattin Tongay",
                "org": ""
            },
            {
                "name": "Hui Deng",
                "org": ""
            },
            {
                "name": "Alex Zettl",
                "org": ""
            },
            {
                "name": "Steven G. Louie",
                "org": ""
            },
            {
                "name": "Feng Wang",
                "org": ""
            }
        ],
        "venue": "arXiv: Mesoscale and Nanoscale Physics",
        "year": 2018
    },
    "ibdlTWwV": {
        "id": "ibdlTWwV",
        "title": "Mortality for robotic- versus video-assisted lobectomy treated stage I non-small cell lung cancer patients",
        "abstract": "Patients with small (≤20 mm) stage I NSCLC treated with RATS-L had statistically significantly higher long-term mortality risk than VATS-L after 1 year postsurgery.",
        "keywords": "",
        "authors": [
            {
                "name": "Yong Cui",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Eric L Grogan",
                "org": "Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Stephen A Deppen",
                "org": "Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Fei Wang",
                "org": "Department of Breast Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China."
            },
            {
                "name": "Pierre P Massion",
                "org": "Division of Allergy, Pulmonary & Critical Care Medicine, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA."
            },
            {
                "name": "Christina E Bailey",
                "org": "Division of Surgical Oncology & Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, TN, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            }
        ],
        "venue": "JNCI cancer spectrum",
        "year": 2020
    },
    "qTR25Q8T": {
        "id": "qTR25Q8T",
        "title": "Biexcitonic optical Stark effects in monolayer molybdenum diselenide",
        "abstract": "Floquet states, where a periodic optical field coherently drives electrons in solids(1-3), can enable novel quantum states of matter(4-6). A prominent approach to realize Floquet states is based on the optical Stark effect. Previous studies on the optical Stark effect often treated the excited state in solids as free quasi-particles(3,7-12). However, exciton-exciton interactions can be sizeably enhanced in low-dimensional systems and may lead to light-matter interactions that are qualitatively different from those in the non-interacting picture. Here we use monolayer molybdenum diselenide (MoSe2) as a model system to demonstrate that the driving optical field can couple a hierarchy of excitonic states, and the many-body inter-valley biexciton state plays a dominant role in the optical Stark effect. Specifically, the exciton-biexciton coupling in monolayer MoSe2 breaks down the valley selection rules based on the non-interacting exciton picture. The photon-dressed excitonic states exhibit an energy redshift, splitting or blueshift as the driving photon frequency varies below the exciton transition. We determine a binding energy of 21 meV for the inter-valley biexciton and a transition dipole moment of 9.3 debye for the exciton-biexciton transition. Our study reveals the crucial role of many-body effects in coherent light-matter interaction in atomically thin two-dimensional materials.",
        "keywords": "",
        "authors": [
            {
                "name": "Chaw-Keong Yong",
                "org": ""
            },
            {
                "name": "Jason Horng",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, USA"
            },
            {
                "name": "Yuxia Shen",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Alex Wang",
                "org": ""
            },
            {
                "name": "Chanshan Yang",
                "org": ""
            },
            {
                "name": "Chung-Kuan Lin",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, USA"
            },
            {
                "name": "Shilong Zhao",
                "org": "Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen, China"
            },
            {
                "name": "Kenji Watanabe",
                "org": "National Institute for Materials Science, Tsukuba, Japan"
            },
            {
                "name": "Takashi Taniguchi",
                "org": "National Institute for Materials Science, Tsukuba, Japan"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, USA"
            },
            {
                "name": "Feng Wang",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, USA"
            },
            {
                "name": "Feng Wang",
                "org": "Department of Physics, University of California at Berkeley, Berkeley, USA"
            }
        ],
        "venue": "NATURE PHYSICS",
        "year": 2018
    },
    "eKxpWgoY": {
        "id": "eKxpWgoY",
        "title": "A Study on the Scale Structure and Evolution of Regional Tourism Economy:In the Case of Shaanxi Province",
        "abstract": "This paper applies hierarchical scale structure theory,primary index and rank-scale analysis methods to analyze the characteristics and evolution of the scale structure of tourism economy in shaanxi province.The result shows: the domestic and inbound tourism are both typical primate distribution,and this structure type does not occur to significant conversion in recent years;It has a significant gaps between the domestic and inbound tourism economics,the primate advantage of inbound tourism is stronger than the domestic tourism,the domestic tourism economy presents a first focus,after the dispersion of the trend,while the entry tourist economy presents the first dispersed after the concentration the trend.The hierarchical scale of domestic and inbound tourism performs as \"middle large\",and the scales of region in middle-level are gradual convergence.",
        "keywords": [
            "Tourism economy",
            "Scale structure",
            "Shaanxi province"
        ],
        "authors": [
            {
                "name": "YU Kanhua",
                "org": ""
            },
            {
                "name": "CAI Hui",
                "org": ""
            }
        ],
        "venue": "Urban Development Studies",
        "year": 2013
    },
    "qyGXnNS6": {
        "id": "qyGXnNS6",
        "title": "Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors.",
        "abstract": "To determine the effects of extracellular matrix and neighboring cells on the differentiation of human embryonic stem cells (hESC) into progenitors of retinal cells and/or retinal pigment epithelium (RPE). HESC were cultured on mouse PA6 stromal cells for approximately 2weeks to obtain neural progenitors. To induce photoreceptor marker expression, the neural progenitors were cultured on a confluent monolayer of ARPE19 or on laminin-coated dishes. To induce RPE markers, the neural progenitors were seeded onto human Bruch’s membrane or Matrigel. Cells were examined morphologically and stained with different RPE or neural progenitor markers. Microarray techniques were used to compare the gene expression profiles of hESC cultured on mouse fibroblasts or neural progenitors on PA6 cells to the transcriptome of the adult neural retina and RPE. HESC cultured on PA6 cells expressed neural progenitor markers β-tubulin III, PAX6, neural filament, GFAP and vimentin. Culturing these neural progenitors on confluent ARPE19 monolayer induced expression of the photoreceptor progenitor cell marker CRX; culturing neural progenitors on laminin substrates induced a neuronal phenotype with neurite formation. Neural progenitors expressed the RPE marker ZO-1 after culturing on Matrigel-coated dishes and the RPE marker Bestrophin after culturing on human Bruch's membrane explants. Hierarchical clustering analysis of samples suggested that when cultured on PA6 stromal cells hESC exhibited genetic characteristics towards differentiating into neural retina. Microarray analysis showed that after culturing on PA6 cells, stem cells expressed 117 new genes; among these there were 22 genes present in neural retina or RPE cells. The functions of these genes were highly related to cell proliferation, nervous system development and cell adhesion. HESC can be induced to differentiate into neural progenitors after culturing on PA6 cells. These neural progenitors can express RPE markers when cultured on Bruch's membrane or Matrigel, or photoreceptor markers when cultured on confluent ARPE19 or laminin. Additional studies are required to assess the function of hESC induced to express retinal or RPE markers prior to successful intraocular transplantation into animal models of retinal degeneration.",
        "keywords": [
            "stem cells",
            "retinal progenitors",
            "extracellular matrix",
            "Bruch's membrane",
            "retinal transplantation"
        ],
        "authors": [
            {
                "name": "Jie Gong",
                "org": "Department of Ophthalmology, Harkness Eye Institute, Columbia University, 635 West 165th Street, New York, USA"
            },
            {
                "name": "Ofer Sagiv",
                "org": "Department of Ophthalmology, Harkness Eye Institute, Columbia University, 635 West 165th Street, New York, USA"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Ophthalmology, Harkness Eye Institute, Columbia University, 635 West 165th Street, New York, USA"
            },
            {
                "name": "Stephen H Tsang",
                "org": "Department of Ophthalmology, Harkness Eye Institute, Columbia University, 635 West 165th Street, New York, USA"
            },
            {
                "name": "Lucian V Del Priore",
                "org": "Corresponding author. Tel.: +1 212 305 2923; fax: +1 212 342 1724."
            }
        ],
        "venue": "Experimental Eye Research",
        "year": 2008
    },
    "Ga2dMq82": {
        "id": "Ga2dMq82",
        "title": "Effect of metoprolol on change of cardiac MMPs-2 & 9 in rats with ISO-induced congestive heart failure",
        "abstract": "Objective: Recent studies have suggested that congestive heart failure(CHF) is a myocardial remodeling and lead to the development and progression of CHF.And Matrix metalloproteinase 2 and 9(MMPs-2 & 9) were the most important factors.This study intends to establish the animal model of isoproterenol(ISO)-induced CHF in rats and to explore the effect of metoprolol on cardiac MMP-2 & 9.Methods: 60 Male Sprague-Dawley rats were randomly allocated to the ISO-induced chronic heart failure group(n=50) receiving two subcutaneous injections of 170 mg ISO per-kilogram of body and the healthy normal group(n=10) receiving two subcutaneous injections of 0.25 ml normal saline.After 6 weeks,the left ventricular ejection fraction(LVEF) were measured by echocardiogram,the remaining rats,with an LVEF≤45%,were randomly divided into two groups: control group(n=10),metoprolol group 8 mg·kg-1·d-1(n=10),the drugs were given i.g.At 18th week,then the hemodynamic parameters were detected,including heart rate,left ventricular end diastolic pressure,left ventricular systolic pressure;LVWI was measured after left ventricular morphopathological examination.the MMP-2 & 9 in cardiac were detected by RT-PCR,real-time PCR and gelatin zymography assay method.Results:(1) Compared with the healthy normal group,the HR,LVEDP,VWI,LVWI and the MMP-2 & 9 in cardiac were significantly increased(P<0.01),but LVSP and ±dp/dtmax were significantly decreased in the control group.(2) Compared with the control group,the HR,LVEDP,VWI,LVWI and the MMP-2 & 9 in cardiac were decreased distinctly.the ±dp/dtmax were increased distinctly(P<0.01) in the metoprolol group.Conclusion: Metoprolol can inhibit the MMP-2 & 9 in cardiac,improve heart function and reverse ventricular remodeling with CHF.",
        "keywords": [
            "matrix metalloproteinases",
            "metoprolol",
            "cardiac fibrosis",
            "congestive heart failure"
        ],
        "authors": [
            {
                "name": "GUO Han",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "LU Le",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Modern Medical Journal",
        "year": 2010
    },
    "UpXgzskt": {
        "id": "UpXgzskt",
        "title": "Small-signal model of vector current-controlled MMC-UPFC",
        "abstract": "Modular multilevel converter based unified power flow controller (MMC-UPFC) projects are different from earlier UPFC projects in control methods and system structures. Characteristics of these MMC-UPFC projects have not been fully researched in the existing literature, so it is difficult to effectively analyse the small-signal stability and low-frequency oscillation characteristics of power system containing these UPFCs. To solve this problem, the small-signal model of vector current-controlled MMC-UPFC is studied. Firstly, the equivalent model of the general structure UPFC is given in this study. Secondly, the dynamic model and small-signal model of UPFC are derived. Thirdly, the method of combining the UPFC model and the rest of the system is presented, so that the linearised model of the whole system can be established. At last, the small-signal model is verified in two test systems by time-domain simulations and modal analysis. Results show that the method proposed in this study is applicable for both the novel structure UPFC and the traditional structure UPFC, and that the small-signal model obtained can accurately reflect system characteristics.",
        "keywords": [
            "time-domain analysis",
            "power transmission control",
            "modal analysis",
            "load flow control",
            "power convertors"
        ],
        "authors": [
            {
                "name": "Jian Yang",
                "org": "Department of Electrical Engineering, Zhejiang University, People's Republic of China"
            },
            {
                "name": "Pengcheng Song",
                "org": "National Electric Power Dispatching and Control Center, State Grid Corporation of China, People's Republic of China"
            },
            {
                "name": "Zheng Xu",
                "org": "Department of Electrical Engineering, Zhejiang University, People's Republic of China"
            },
            {
                "name": "Huangqing Xiao",
                "org": "Department of Electrical Engineering, Zhejiang University, People's Republic of China"
            },
            {
                "name": "Hui Cai",
                "org": "Economic Research Institute, State Grid Jiangsu Electric Power Co. Ltd., People's Republic of China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "Economic Research Institute, State Grid Jiangsu Electric Power Co. Ltd., People's Republic of China"
            }
        ],
        "venue": "IET Generation, Transmission & Distribution",
        "year": 2019
    },
    "5L8ygRvo": {
        "id": "5L8ygRvo",
        "title": "EFFECTS OF TETRAMETHYLPYRAZINE ON THE PRODUCTION OF ET AND NO IN CARDIAC FIBROBLASTS IN NEONATE RAT",
        "abstract": "Objective: To investigate the effects of tetramethylpyrazine(tmp) on the production of endothelin(ET) and nitric oxide(NO) in cardiac fibroblasts(CFs) in neonate rat.Methods: CFs were isolated by trypsin digestion method,the changes of ET and NO production from CFs were examined by radioimmunoassay,nitrate reductase-dependent assay,respectively.Results: TMP decreased ET synthesis in a concentration-dependent manner(P<0.05),but showed no significant changes to NO production(P>0.05).Conclusion: These results showed that TMP can decrease the production of ET and influence the balance of these factors.TMP may inhibit cardiac fibrosis by modulating these cytokines.",
        "keywords": [
            "tetramethylpyrazine",
            "cardiac fibroblasts",
            "nitric oxide",
            "endothelin"
        ],
        "authors": [
            {
                "name": "ZHAO Zhi-ming",
                "org": "Nanjing University of Traditional Chinese Medicine and Pharmacy,Nanjing  China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing University of Traditional Chinese Medicine and Pharmacy,Nanjing  China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Nanjing University of Traditional Chinese Medicine and Pharmacy,Nanjing  China"
            }
        ],
        "venue": "Acta Academiae Medicinae Neimongol",
        "year": 2006
    },
    "uXmT1xpv": {
        "id": "uXmT1xpv",
        "title": "Abnormal band bowing effects in phase instability crossover region of GaSeTe  nanomaterials.",
        "abstract": "Akin to the enormous number of discoveries made through traditional semiconductor alloys, alloying selected 2D semiconductors enables engineering of their electronic structure for a wide range of new applications. 2D alloys have been demonstrated when two components crystallized in the same phase, and their bandgaps displayed predictable monotonic variation. By stabilizing previously unobserved compositions and phases of GaSeTe  at nanoscales on GaAs(111), we demonstrate abnormal band bowing effects and phase instability region when components crystallize in different phases. Advanced microscopy and spectroscopy measurements show as tellurium is alloyed into GaSe, nanostructures undergo hexagonal to monoclinic and isotropic to anisotropic transition. There exists an instability region (0.56 < x < 0.67) where both phases compete and coexist, and two different bandgap values can be found at the same composition leading to anomalous band bowing effects. Results highlight unique alloying effects, not existing in single-phase alloys, and phase engineering routes for potential applications in photonic and electronics.",
        "keywords": "",
        "authors": [
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA. hui.cai@asu.edu."
            },
            {
                "name": "Bin Chen",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Mark Blei",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Shery L Y Chang",
                "org": "LeRoy Eyring Center for Solid State Science, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Kedi Wu",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Houlong Zhuang",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, 85287, USA. Sefaattin.Tongay@asu.edu."
            }
        ],
        "venue": "Nature communications",
        "year": 2018
    },
    "l4hVaSSA": {
        "id": "l4hVaSSA",
        "title": "Abstract 2251: Tumor tissue gene expression in association with survival of triple-negative breast cancer",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shuyang Wang",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Ping-Ping Bao",
                "org": ""
            },
            {
                "name": "Jie Wu",
                "org": ""
            },
            {
                "name": "Fei Ye",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Ying Zheng",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2017
    },
    "Kofbkt0D": {
        "id": "Kofbkt0D",
        "title": "Changing of left ventricular myocardial tissue local angiotensin Ⅱin rat with pressure overload",
        "abstract": "Aim To observe the changing of left ventricular myocardial tissue local angiotensin Ⅱ in rat with pressure overload,and study the possible mechanism of left ventricular remodeling in rat with pressure overload.Methods 20 SD male rats were randomly divided into sham operation group and model group.The rat model with pressure overload by abdominal aortic constriction was used as the model group.The changes of left ventricular mass index(LVMI) was observed.Radioimmunoassay was used to detect left ventricular myocardial tissue local angiotensin Ⅱ(AngⅡ).Results After 8 weeks,LVMI in model group was higher than that in sham operation group respectively(P<0.01).The AngⅡ level of left ventricular myocardial tissue in model group was higher than that of sham operation group(P<0.01).Conclusion The left ventricular remodeling maybe concerned with AngⅡ level of left ventricular myocardial tissue in rat with pressure overload.",
        "keywords": [
            "left ventricular remodeling",
            "tissue RAS",
            "angiotensin Ⅱ",
            "pressure overload"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2010
    },
    "Tb6QCliB": {
        "id": "Tb6QCliB",
        "title": "The research development of the immunosuppress drugs by the target of the dendritic cell",
        "abstract": "Dendritic cells are the most important special professional antigen presenting cells.It can stimulate the proliferation of the original T cells.They are the original power of the body's immune response.Dendritic cells play an important part of the cell's immune response and the body's immune response.This paper mainly introduces the immunosuppress drugs by the target of the dendritic cells.",
        "keywords": [
            "Immunosuppress",
            "Dendritic cell",
            "Drugs"
        ],
        "authors": [
            {
                "name": "GAO Peifang",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "YAO Rubing",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Osteoporosis",
        "year": 2009
    },
    "OBul1Eqg": {
        "id": "OBul1Eqg",
        "title": "Self-Driven Photodetector and Ambipolar Transistor in Atomically Thin GaTe-MoS2 p-n vdW Heterostructure.",
        "abstract": "Heterostructure engineering of atomically thin two-dimensional materials offers an exciting opportunity to fabricate atomically sharp interfaces for highly tunable electronic and optoelectronic devices. Here, we demonstrate abrupt interface between two completely dissimilar material systems, i.e, GaTe-MoS2 p-n heterojunction transistors, where the resulting device possesses unique electronic properties and self-driven photoelectric characteristics. Fabricated heterostructure transistors exhibit forward biased rectifying behavior where the transport is ambipolar with both electron and hole carriers contributing to the overall transport. Under illumination, photoexcited electron-hole pairs are readily separated by large built-in potential formed at the GaTe-MoS2 interface efficiently generating self-driven photocurrent within <10 ms. Overall results suggest that abrupt interfaces between vastly different material systems with different crystal symmetries still allow efficient charge transfer mechanisms at the interface and are attractive for photoswitch, photodetector, and photovoltaic applications because of large built-in potential at the interface.",
        "keywords": [
            "ambipolar behavior",
            "dissimilar material systems",
            "p−n heterojunction",
            "rectification",
            "self-driven photocurrent"
        ],
        "authors": [
            {
                "name": "Shengxue Yang",
                "org": "School of Materials Science and Engineering, Beihang University , Beijing 100191, P.R. China."
            },
            {
                "name": "Cong Wang",
                "org": "The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEAD Applied Physics Institute and School of Physics, Nankai University , Tianjin 300457, China."
            },
            {
                "name": "Can Ataca",
                "org": "Department of Materials Science and Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States."
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences , Beijing 100083, China."
            },
            {
                "name": "Hui Chen",
                "org": "State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences , Beijing 100083, China."
            },
            {
                "name": "Hui Cai",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University , Tempe, Arizona 85287, United States."
            },
            {
                "name": "Aslihan Suslu",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University , Tempe, Arizona 85287, United States."
            },
            {
                "name": "Jeffrey C Grossman",
                "org": "Department of Materials Science and Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States."
            },
            {
                "name": "Chengbao Jiang",
                "org": "School of Materials Science and Engineering, Beihang University , Beijing 100191, P.R. China."
            },
            {
                "name": "Qian Liu",
                "org": "The MOE Key Laboratory of Weak-Light Nonlinear Photonics, TEAD Applied Physics Institute and School of Physics, Nankai University , Tianjin 300457, China."
            },
            {
                "name": "Sefaattin Tongay",
                "org": "School for Engineering of Matter, Transport and Energy, Arizona State University , Tempe, Arizona 85287, United States."
            }
        ],
        "venue": "ACS applied materials & interfaces",
        "year": 2016
    },
    "u4xrDB7D": {
        "id": "u4xrDB7D",
        "title": "The Royal Opera's 150th anniversary of Puccini's birth:Turandot",
        "abstract": "Turandot is one of the most spectacular productions of The Royal Opera.Directed by Andrei Serban,this production has since become a classic portraying the:the pageantry,color and savagery of ancient China.This time,acclaimed Italian conductor Nicola Luisotti returns to conduct two casts of great international voices,headed up by Jose Cura and Irene Theorin as Calaf and Turandot respectively.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2009
    },
    "G7kHZH6Q": {
        "id": "G7kHZH6Q",
        "title": "Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "frank chavez",
                "org": ""
            },
            {
                "name": "paul j dunford",
                "org": ""
            },
            {
                "name": "andrew greenspan",
                "org": ""
            },
            {
                "name": "steven p meduna",
                "org": ""
            },
            {
                "name": "jorge a quiroz",
                "org": ""
            },
            {
                "name": "brad m savall",
                "org": ""
            },
            {
                "name": "kevin l tays",
                "org": ""
            },
            {
                "name": "robin l thurmond",
                "org": ""
            },
            {
                "name": "jianmei wei",
                "org": ""
            },
            {
                "name": "ronald l wolin",
                "org": ""
            },
            {
                "name": "xiaohu zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "zVDtVZjd": {
        "id": "zVDtVZjd",
        "title": "Expressions of P57~(Kip2) and Ki67 antigen in the diagnosis of hydatidiform mole and hytrophic abortus",
        "abstract": "Objective:To study the expressions of P57Kip2 and Ki67 antigen in hydatidiform moles and hytrophic abortus and their effects on differential diagnosis.Methods:182 cases of hydatidiform moles and hytrophic abortus of fomalin-fixed tissues were evaluated by immunohistochemistry using nonocolonal antibody against P57Kip2 and Ki67 antigen.Results:Nuclear P57Kip2 protein were not expressed in complete hydatidiform moles cases,whereas,nuclear Ki67 antigen was strongly expressed.Nuclear P57Kip2 protein were expressed in both partial hydatidiform moles cases and hytrophic abortus cases,whereas,much higher expression rate of Ki67 was showed in the former(P<0.01).Conclusion:The immunohistochemical analysis for P57Kip2 and Ki67 antigen expression can be a easy and useful tool for the differential diagnosis between complete hydatidiform moles and partial hydatidiform moles and hytrophic abortus.",
        "keywords": [
            "P57Kip2",
            "Ki67",
            "Hytrophic abortus",
            "Hydatidiform mole"
        ],
        "authors": [
            {
                "name": "LIU Xiao-Gang",
                "org": ",et al.Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ",et al.Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            },
            {
                "name": "MA Yu-Lin",
                "org": ",et al.Department of Pathology,Chuiyangliu Hospital of Beijing,Beijing ,China"
            }
        ],
        "venue": "Maternal and Child Health Care of China",
        "year": 2013
    },
    "UVaJB4aw": {
        "id": "UVaJB4aw",
        "title": "Determination of bone mineral density in the lateral lumbar vertebra by Prodigy dual-energy X-ray absorptiometry in two ways",
        "abstract": "Objective:To investigate the consistency of two methods in the measurement of bone mineral density in the lateral lumbar vertebra.Methods:The bone mineral densities of the 2nd,3rd and 4th lumbar vertebras in 18 female patients,at a preset side lying position,were measured respectively by two methods(lateral spine analysis,LS and lateral vertebral analysis,LVA) provided by the dual-energy(X-ray) absorptiometry(GE Lunar,Prodigy).The results were recorded and analyzed by SPSS(Version(10.0).) The values of bone mineral density were displayed by boxplot,paired and analyzed by(Wilcoxon's) signed rank test and(Pearson's) correlation analysis.Statistical significance was considered when P<(0.05.) Results:The data distributions measured by the two different methods were accordant.The data form the two groups were not statistically different under Wilcoxon's signed rank test(P>(0.05),) and were clearly correlated(P<0.001) under Pearson's correlation analysis.Conclusion:The results of the two methods for the measurement of bone mineral density in the lateral lumbar vertebras were coherent.",
        "keywords": [
            "Lateral lumbar vertebras",
            "Dual-energy X-ray absorptiometry",
            "Boxplot"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "A66hjggC": {
        "id": "A66hjggC",
        "title": "Effects of Bushen Kangsong Pellet on Bone Mineral Density in Postmenopausal Osteoporosis",
        "abstract": "Objective:To explore the effects of Bushen Kangsong Pellet on bone mineral density(BMD) in postmenopausal osteoporosis.Methods: Eighty-four patients with postmenopausal osteoporosis were divided into two groups at random.The observed group was treated with Bushen Kangsong Pellet and calcium tablet,and the control group only with calcium tablet.The course of treatment was six months.Then the BMD in orthotope lumbar vertebra was measured with Dual Energy X-ray Absorptiometry(GE Lunar Prodigy).Results: Negative correlation was observed between BMD and the years of menopause through dependability analysis before treatment(r=-0.254,P<0.05),but there was no correlation after treatment(r=-0.159,P>0.05).The BMD of the observed group was significantly higher after treatment(t=3.976,P<0.01).There was significantly statistics difference between two groups(t=3.297,P<0.01;95% CI(0.010,0.042)).Conclusion: A tendency that the BMD of the patients in postmenopausal osteoporosis decreases year by year is observed,and Bushen Kangsong Pellet can reverse this tendency.BMD could not be increased when only treated with calcium tablet.",
        "keywords": [
            "Postmenopausal osteoporosis",
            "Bone mineral density",
            "Bushen Kangsong Pellet"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHANG Yong-wen",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZANG Xu-li",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "WEI Qun-li",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2008
    },
    "T2wXEvZh": {
        "id": "T2wXEvZh",
        "title": "Abstract 1735: Fruit and vegetable consumption and risk of gastric cancer: a prospective nested case-control study in China, Japan and Korea",
        "abstract": "Introduction: Epidemiological findings on the association between fruit and vegetable consumption and gastric cancer risk remain inconsistent, resulting in the designation of fruits and vegetables as “probable” and “possible” respectively, but not “convincing”, protective factors. However, intervention studies provide support for the effect of micronutrient supplementation in the prevention of gastric cancer and its precursor lesions, though the effects remain less substantial than for Helicobacter pylori (H. pylori) eradication. Objective: To ascertain the association between fruit and vegetable intake and non-cardia gastric cancer incidence with adjustment for H. pylori within East Asian cohort studies. Methods: The present analysis includes 1970 participants (810 prospectively ascertained non-cardia gastric cancer cases with 1160 matched controls) from 5 cohort studies in the Helicobacter pylori Biomarker Cohort Consortium. These cohorts collected blood samples as well as demographic, lifestyle, and dietary data at baseline. Pre-diagnostic antibody levels to 15 H. pylori proteins were assessed using multiplex serology. Conditional logistic regression, adjusting for total energy intake, smoking, and H. pylori status, was applied to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for gastric cancer risk across cohort- and sex-specific quartiles of fruit and vegetable intake. Results: Increasing fruit intake was significantly associated with decreasing risk of non-cardia gastric cancer, so that individuals in the highest quartile of fruit consumption had a 29% reduced odds of gastric cancer, compared to individuals in the lowest quartile (OR = 0.71, 95% CI, 0.52-0.95, P for trend = 0.02). Compared to CagA-positive H. pylori low fruit consumers, the strongest inverse association of gastric cancer risk was amongst those high fruit consumers without evidence of H. pylori antibodies (OR = 0.12, 95% CI: 0.06-0.25), whereby the inverse association by increasing fruit consumption was attenuated among individuals infected with CagA-positive H. pylori (OR = 0.82, 95% CI: 0.66-1.03). We observed a weaker, non-dose-response suggestion of an inverse association of vegetable intake with non-cardia gastric cancer risk. Conclusions: To our knowledge, this is the largest prospective study in the high-risk region of East Asia to examine the association of fruit and vegetable consumption with non-cardia gastric cancer risk adjusted for H. pylori. We have found that high fruit intake may play a role in decreasing risk of non-cardia gastric cancer, even after adjustment for H. pylori subtype-specific infection. Funding: R01 CA174853   Citation Format:  Tianyi Wang, Hui Cai, Shizuka Sasazuki, Shoichiro Tsugane, Wei Zheng, Eo Rin Cho, Sun Ha Jee, Angelika Michel, Michael Pawlita, Yong-Bing Xiang, Yu-Tang Gao, Xiao-Ou Shu, Weicheng You, Meira Epplein. Fruit and vegetable consumption and risk of gastric cancer: a prospective nested case-control study in China, Japan and Korea. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 1735.",
        "keywords": "",
        "authors": [
            {
                "name": "Tianyi Wang",
                "org": "Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital and Institute, Beijing, China;"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN;"
            },
            {
                "name": "Shizuka Sasazuki",
                "org": "Epidemiology and Prevention Group, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan;"
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Epidemiology and Prevention Group, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan;"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN;"
            },
            {
                "name": "Eo Rin Cho",
                "org": "Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea;"
            },
            {
                "name": "Sun Ha Jee",
                "org": "Department of Epidemiology and Health Promotion, Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea;"
            },
            {
                "name": "Angelika Michel",
                "org": "Division of Molecular Diagnostics of Oncogenic Infections, Research Program in Infection, Inflammation, and Cancer, German Cancer Research Center (DFKZ), Heidelberg, Germany;"
            },
            {
                "name": "Michael Pawlita",
                "org": "Division of Molecular Diagnostics of Oncogenic Infections, Research Program in Infection, Inflammation, and Cancer, German Cancer Research Center (DFKZ), Heidelberg, Germany;"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN;"
            },
            {
                "name": "Wei-Cheng You",
                "org": "Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital and Institute, Beijing, China;"
            },
            {
                "name": "Meira Epplein",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN;"
            }
        ],
        "venue": "Cancer Research",
        "year": 2016
    },
    "H2BEA2a6": {
        "id": "H2BEA2a6",
        "title": "Opera Crossword Puaales",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "P5bfngTg": {
        "id": "P5bfngTg",
        "title": "Expression of Transcription Factors Involved in Murine Stem Cell Differentiation Induce Photoreceptor Phenotypes in Mouse Embryonic Stem Cells",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "mark a fields",
                "org": "columbia university"
            },
            {
                "name": "l vickers",
                "org": "columbia university"
            },
            {
                "name": "hui cai",
                "org": "columbia university"
            },
            {
                "name": "jie gong",
                "org": "columbia university"
            },
            {
                "name": "stephen tsang",
                "org": "columbia university"
            },
            {
                "name": "lucian v del priore",
                "org": "columbia university"
            }
        ],
        "venue": "Investigative Ophthalmology & Visual Science",
        "year": 2011
    },
    "MAfFfcor": {
        "id": "MAfFfcor",
        "title": "Anti-inflammatory and Immunomodulation Effects of Panax Notoginseng Saponins in Rats with Adjuvant Arthritis",
        "abstract": "Objective:To investigate the anti-inflammatory and immunomodulation effects of panax notoginseng saponins(PNS) in rats with adjuvant arthritis(AA).Methods:Complete Freund's adjuvant was used to induce AA in rats.Polyarthritis index were scored and levels of tumour necrosis factor-α(TNF-α) and interleukin-1β(IL-1β)from serum were determined by radio immunoassay.Meanwhile,levels of TNF-α and IL-1β produced by LPS-induced PM of AA rats were also determined by radio immunoassay.Results:PNS were given by intraperitoneal injection for 2 weeks from the 15th day after immunization.The polyarthritic symptoms of AA rats were improved significantly compared with those of AA model group(P<0.05).PNS significantly reduced the enhanced productions of TNF-α(P<0.01) and IL-1β(P<0.05)from serum in AA rats.Meanwhile,PNS significantly reduced the enhanced productions of TNF-α(P<0.05,or P<0.01) and IL-1β(P<0.05)produced by LPS-induced PM of AA rats at different concentration(0.8,0.4 and 0.2 mg/ml,respectively).Conclusion:PNS has therapeutic effect on AA in rats,which may be related to anti-inflammatory and immunomodulation effects of inhibiting productions of proinflammatory cytokines of TNF-α and IL-1β from serum and LPS-induced PM.",
        "keywords": [
            "Interleukin-1β",
            "Tumor necrosis factor",
            "Panax notoginseng saponins",
            "Adjuvant arthritis"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2009
    },
    "g4aNfNDJ": {
        "id": "g4aNfNDJ",
        "title": "Quantitative evaluation on the effect of Lujiao prescription on cardiac function of patients with congestive heart failure",
        "abstract": "BACKGROUND: Congestive heart failure (CHF) is the clinical syndrome of all kinds of heart disease on the serious or final stage. About half of patients with organic heart disease will have heart failure that has a high incidence rate and mortality. The survival of heart failure was inferior to that of malignant tumor. OBJECTIVE: To confirm the clinical effect of Lujiao prescription on CHF and elucidate its possible mechanism. DESIGN: A control observation on CHF patients. SETTING: Department of Cardiovasology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. PARTICIPANTS: A total of 60 patients with CHF were selected from the department of cardiovasology in Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from January 1996 to December 1998. There were 31 male and 29 female. Included criteria: ①All of patients were consistent with Framinham diagnostic criteria. ② Above Ⅲ degree by New York Heart Association(NYHA). ③ Three months case history. ④Accept quantity sufficient diuretic and vasodilating agent (exclude angiotensin converting enzyme inhibitor ). ⑤ Left ventricle hypertrophy was proved by echocardiogram or chest X-ray. ⑥ Differentiation of symptoms and signs of Traditional Chinese Medicine refers to asthenia syndrome of differentiation of symptoms and signs of Traditional Chinese Medicine (1986, Researching Association of Chinese integrated medicine) General state of health and basic disease of the patients in the two groups were not significant deviation. METHODS: 60 patients of CHF were randomly divided into Lujiao prescription group(n=40) and Digoxin group (n=20) at the rate of 2:1. Lujiao prescription group: Orally liquid decoction of Lujiao Prescription 35 mL(1 mL contain crude drug 1.6 g) Bid. po. Course of treatment: 4 weeks. Digoxin group: Digoxin tablet, 0.125-0.25 mg, qd. po. course of treatment: 4 weeks. After 4-week treatment, the patients' clinical effect, integrals of the symptoms of renal deficiency, classification of function capacity of the NYHA, Lee's heart failure score, heart rate(HR), myocardium oxygen consumption(MOC), proportion of heart to chest, echocardiogram, measurement of plasma angitentionⅡ(AngⅡ) and plasma atrial natriuretic factor (ANF) were observed. MAIN OUTCOME MEASURES: ① The total clinic effective rate. ② Integrals of the symptoms of renal deficiency. ③ Classification of function capacity of the NYHA. ④ Lee's heart failure score. ⑤HR and MOC. ⑥ The proportion of heart to chest. ⑦ Ejection fraction(EF), cardic output (CO), interventricular septal thickness(IVST), posterior wall thickness(PWT) and left ventricular mass index (LVMI) through echocardiogram. ⑧ The measurement of plasma AngⅡand plasma ANF. RESULTS:Totauy 60 patients entered the final analysis. ① The total clinical effective rate of the Lujiao prescription group was 90 %, which showed no significant difference from the Digoxin group (90 %, P > 0.05).② Improvement was significantly observed in the integrals of the symptom of renal deficiency of the patients in the Lujiao prescription group after treatment (P < 0.01), but which was not significant in the Digoxin group(P > 0.05). ③ It was found that classification of functional capacity of NYHA between Lujiao prescription group and Digoxin group after treatment was obviously decreased (P < 0.01). ④ Lee's heart failure score of patients in Lujiao prescription group and Digoxin group after treatment was decreased (P < 0.01). ⑤Myocardium oxygen consumption and HR of the patients in the Lujiao prescription group and Digoxin group after treatment was decreased (P < 0.01). ⑥ The proportion of heart to chest between Lujiao prescription group and Digoxin group after treatment was decreased (P < 0.01). ⑦ EF and CO were increased by Lujiao prescription and by Digoxin(P < 0.01,vs pretreatment, respectively). IVST, PWT, LVMI of Lujiao prescription group after treatment were obviously decreased (P < 0.01), while those of the Digoxin group were not obviously decreased (P > 0.05). ⑧ The level of plasma AngⅡof the patients in the Lujiao prescription group after treatment were obviously decreased (P < 0.01), while that of the Digoxin group were not obviously decreased (P > 0.05). The level of plasma ANF was decreased by Lujiao prescription and by digoxin(P < 0.01, vs pretreatment, respectively). CONCLUSION: There is increasing cardiac constriction power and regressing left ventricular hypertrophy of patients with CHF by Lujiao prescription. The therapeutical effect of Lujiao prescription for CHF is better than that of Digoxin. The effect may be related to the regulation of circular or local endocrine(plasma AngⅡ and ANF) disorder.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing ,Jiangsu province, China"
            },
            {
                "name": "Hu Wan-ying",
                "org": "Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai , China"
            },
            {
                "name": "Wang Yan-jun",
                "org": "Post doctor Institute of Hebei Medical University, Shijiazhuang ,Hebei Province,China"
            },
            {
                "name": "Zhang Jun-hui",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing ,Jiangsu province, China"
            },
            {
                "name": "Guo Jun-hao",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing ,Jiangsu province, China"
            },
            {
                "name": "Hu Bing",
                "org": "Department of Integrated Traditional and Western Medicine, Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA, Nanjing ,Jiangsu province, China"
            }
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2006
    },
    "uPWwn5AV": {
        "id": "uPWwn5AV",
        "title": "Abstract 891: Association of genetic polymorphisms of SIPA1 with breast cancer risk and survival among Chinese women",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "regina courtney",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "s qu",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "jirong long",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2014
    },
    "yiqOJFvZ": {
        "id": "yiqOJFvZ",
        "title": "Controlling Structural Anisotropy of Anisotropic 2D Layers in Pseudo-1D/2D Material Heterojunctions.",
        "abstract": "Chemical vapor deposition and growth dynamics of highly anisotropic 2D lateral heterojunctions between pseudo-1D ReS2 and isotropic WS2 monolayers are reported for the first time. Constituent ReS2 and WS2 layers have vastly different atomic structure, crystallizing in anisotropic 1T and isotropic 2H phases, respectively. Through high-resolution scanning transmission electron microscopy, electron energy loss spectroscopy, and angle-resolved Raman spectroscopy, this study is able to provide the very first atomic look at intimate interfaces between these dissimilar 2D materials. Surprisingly, the results reveal that ReS2 lateral heterojunctions to WS2 produce well-oriented (highly anisotropic) Re-chains perpendicular to WS2 edges. When vertically stacked, Re-chains orient themselves along the WS2 zigzag direction, and consequently, Re-chains exhibit six-fold rotation, resulting in loss of macroscopic scale anisotropy. The degree of anisotropy of ReS2 on WS2 largely depends on the domain size, and decreases for increasing domain size due to randomization of Re-chains and formation of ReS2 subdomains. Present work establishes the growth dynamics of atomic junctions between novel anisotropic/isotropic 2D materials, and overall results mark the very first demonstration of control over anisotropy direction, which is a significant leap forward for large-scale nanomanufacturing of anisotropic systems.",
        "keywords": [
            "chemical vapor deposition",
            "heterostructures",
            "HRSTEM",
            "rhenium disulfide"
        ],
        "authors": [
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Kedi Wu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Aslihan Suslu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sijie Yang",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Aliya Yano",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Emmanuel Soignard",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Toshihiro Aoki",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Katia March",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Yuxia Shen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "ADVANCED MATERIALS",
        "year": 2017
    },
    "kU8BrL4A": {
        "id": "kU8BrL4A",
        "title": "Association of endometrial cancer risk with a functional polymorphism (Asp327Asn) in the sex hormone-binding globulin gene",
        "abstract": "BACKGROUND. Sex steroid hormones play a central role in the development of endometrial cancer. Sex hormone-binding globulin (SHBG) modulates the bioavailability of circulating sex hormones and regulates their signaling systems in target cells. Epidemiologic studies have demonstrated that blood SHBG levels are associated inversely with the risk of endometrial cancer. A functional polymorphism, an amino acid substitution of asparagine (Asp) for aspartic acid (Asn) at residue 327 (Asp(327)Asn) (reference sequence 6259), in the SHBG gene recently was identified and has been associated with an increased half-life and elevated blood levels of SHBG. The authors tested the hypothesis that this genetic variance is associated with a reduced risk of endometrial cancer in the Shanghai Endometrial Cancer Study, a population-based, case-control study that was conducted in urban Shanghai, China between 1997 and 2003. METHODS. This study included 1037 women with newly diagnosed endometrial cancer ages 30 years and 69 years and 1031 age-matched controls from the community who had completed an in-person interview and donated a blood and/or buccal cell sample to the study. Genotyping for the Asp(327)Asn polymorphism was performed by using the TaqMan method. Odds ratio (ORs) and 95% confidence intervals (95% CIs) derived from logistic regression models were used to evaluate the association between the genetic variation and endometrial cancer risk. RESULTS. The allele frequencies of Asn were 15.0% in cases and 17.1% in controls (P = .06). The variant Asn 327 allele was associated with a reduced risk of endometrial cancer in postmenopausal women (OR, 0.72; 95% CI, 0.55-0.93) but not in premenopausal women (OR, 1.02; 95% CI, 0.74-1.42). The inverse association was more pronounced among postmenopausal women who had a low body mass index (OR, 0.48; 95% CI, 0.31-0.76) or longer years of menstruation (OR, 0.64; 95% CI, 0.46-0.89), although the results from tests for multiplicative interaction were not statistically significant. CONCLUSIONS. The current results suggested that the codon 327 Asn allele in the SHBG gene may be related to a reduced risk of endometrial cancer among postmenopausal women.",
        "keywords": [
            "polymorphism",
            "endometrial cancer",
            "epidemiology",
            "sex hormone-binding globulin"
        ],
        "authors": [
            {
                "name": "Nobuhiko Kataoka",
                "org": "Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA."
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Wang Hong Xu",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            }
        ],
        "venue": "CANCER",
        "year": 2007
    },
    "50xtpGBx": {
        "id": "50xtpGBx",
        "title": "Design of a Balanced Three-Phase Power Supply Soft-Switching Based on Single-Phase Inverter Power",
        "abstract": "To eliminate the negative effects caused by three-phase unbalanced distribution, a novel soft-switching system based on single-phase inverter is proposed. The system achieves three-phase equilibrium distribution by adjusting the power supply of the electric equipments. This paper presents a track strategy named regulating frequency to promise no impulse current, which means regulating the output frequency of the inverter to make the output voltage of the inverter synchronize with the grid voltage. Firstly, make the output voltage of the inverter synchronize with the voltage of original access phase, then switch the electric equipment to the inverter. Secondly, make the output voltage of the inverter synchronize with the voltage of alternative access phase, then switch the electric equipment to the alternative access phase to accomplish the soft-switching. MATLAB software and experiment are used to carry out verification for this system. The result shows that the impulse current is practically zero when the electric equipments are switching. The system achieves soft-switching.",
        "keywords": [
            "soft-switching",
            "single-phase inverter",
            "adjust frequency",
            "DSP"
        ],
        "authors": [
            {
                "name": "hui cai",
                "org": "China Jiliang Univ, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "hong yan",
                "org": "China Jiliang Univ, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "wei min chen",
                "org": "China Jiliang Univ, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "qing li",
                "org": "China Jiliang Univ, Hangzhou, Zhejiang, Peoples R China"
            }
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2013
    },
    "VQHD3JHW": {
        "id": "VQHD3JHW",
        "title": "Prospective Cohort Study of Central Adiposity and Risk of Death in Middle Aged and Elderly Chinese",
        "abstract": "",
        "keywords": [
            "cohort studies",
            "death rates"
        ],
        "authors": [
            {
                "name": "shaneda warren andersen",
                "org": "vanderbilt university"
            },
            {
                "name": "xiaoou shu",
                "org": "vanderbilt university"
            },
            {
                "name": "y gao",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "xianglan zhang",
                "org": "vanderbilt university"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "g yang",
                "org": "vanderbilt university"
            },
            {
                "name": "honglan li",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "yongbing xiang",
                "org": "shanghai jiao tong university"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2015
    },
    "mYmy1VWe": {
        "id": "mYmy1VWe",
        "title": "Genetic polymorphisms in obesity-related genes and endometrial cancer risk: Adipokine Genes and Endometrial Cancer",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "xiaoli chen",
                "org": ""
            },
            {
                "name": "jiarong cheng",
                "org": ""
            },
            {
                "name": "wanqing wen",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "jirong long",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            }
        ],
        "venue": "Cancer",
        "year": 2012
    },
    "xVEMDj9x": {
        "id": "xVEMDj9x",
        "title": "Randomized,controlled trial of therapy for risedronate sodium capsules in postmenopausal osteoporosis",
        "abstract": "Objective:To observe availability and security of risedronate sodium capsules on prevention and treatment for postmenopausal osteoporosis. Methods:This is a randomized double-blind placebo-controlled clinical research. All patients were randomly divided into 2 groups, trail group and control group. During 12 months, patients of trail group took risedronate sodium capsules orally every morning, patients of control group took placebo orally every morning, at the same time with all patients taking calcichew D orally every night. The double-energy bone density measurement was used to measure lumbar and hip bone density was measured and lateral thoracolumbar vertebrae radiograph was took 3 times, before treatment, after 6 months and 12 months. Many security indicators were observed at the same time, such as electrocardiogram, blood and urine routine, liver and renal functions. Results:42 patients had been involved in the clinical research program. Compared with control group of the sample change data of lumbar bone density of trail group after 6 and 12 months continuous treatment has both statistical significance. The sample change data for hip bone density of trail group show that there are no statistical significance compared with that of control group. All the security indicators had no abnormal change and no bone fragility fracture incident was observed during this whole program period. Conclusion: From this program , risedronate sodium capsules could be effective and secure on treating postmenopausal osteoporosis. The lumbar bone density of patients could increase obviously during 6 months continuous treatment.",
        "keywords": [
            "Risedronate sodium capsules",
            "Osteoporosis",
            "Randomized control",
            "Clinical trials"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": " Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "YAO Ru-bing",
                "org": " Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": " Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "LIU Yu-xiu",
                "org": " Department of Medical Affairs, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , Jiangsu, China"
            },
            {
                "name": "ZHENG Jun",
                "org": " Department of Medical Affairs, Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing , Jiangsu, China"
            },
            {
                "name": "CAI Hui",
                "org": " Department of Integrated Traditional Chinese and Western Medicine"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "i4RQgle8": {
        "id": "i4RQgle8",
        "title": "Nonexercise physical activity and inflammatory and oxidative stress markers in women",
        "abstract": "Background: Leisure time exercise has been linked to lower circulating levels of inflammatory markers. Few studies have examined the association of nonexercise physical activity with markers of inflammation and oxidative stress. Methods: This cross-sectional analysis included 1005 Chinese women aged 40-70 years. Usual physical activity was assessed through in-person interviews using a validated physical activity questionnaire. Plasma proinflammatory cytokines and urinary F-2-isoprostanes were measured. Multivariable linear models were used to evaluate the association of inflammatory and oxidative stress markers with nonexercise physical activity and its major components. Results: Nonexercise physical activity accounted for 93.8% of overall physical activity energy expenditure. Levels of nonexercise physical activity were inversely associated with circulating concentrations of interleukin (IL)-6 (P-trend=0.004), IL-1 (P-trend=0.03) and tumor necrosis factor-alpha (TNF-) (P-trend=0.01). Multivariable-adjusted concentrations of these cytokines were 28.2% for IL-6, 22.1% for IL-1, and 15.9% for TNF- lower in the highest quartile of nonexercise physical activity compared with the lowest quartile. Similar inverse associations were found for two major components of nonexercise physical activity, walking and biking for transportation, and household activity. No significant associations were observed between nonexercise physical activity and oxidative stress markers. Conclusion: Daily nonexercise physical activity is associated with lower levels of systemic inflammation. This finding may have important public health implications because this type of activity is the main contributor to overall physical activity among middle-aged and elderly women.",
        "keywords": [],
        "authors": [
            {
                "name": "Sheng Hui Wu",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Xianglan Zhang",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Ginger L. Milne",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Clin Pharmacol, Nashville, TN 37203 USA"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Nathaniel R. Rothman",
                "org": "NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA"
            },
            {
                "name": "Yutang Gao -",
                "org": "Shanghai Canc Inst, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ Sch Med, Dept Med, Div Epidemiol, Nashville, TN 37203 USA"
            }
        ],
        "venue": "JOURNAL OF WOMENS HEALTH",
        "year": 2014
    },
    "KdzxA2jY": {
        "id": "KdzxA2jY",
        "title": "Changes of myocardial collagen type I and type III in rat models of abdominal aorta coarctation and their mRNA expressions.",
        "abstract": "",
        "keywords": [
            "immunohistochemistry",
            "messenger rna"
        ],
        "authors": [
            {
                "name": "dong xiaolei",
                "org": ""
            },
            {
                "name": "jiao dongdong",
                "org": ""
            },
            {
                "name": "zhao lingjie",
                "org": ""
            },
            {
                "name": "shen siyu",
                "org": ""
            },
            {
                "name": "cai hui",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "PcqZVdlE": {
        "id": "PcqZVdlE",
        "title": "Changes in quality of life among breast cancer patients three years post-diagnosis.",
        "abstract": "To evaluate changes in quality of life (QOL) and identify medical and socio-demographic predictors of QOL among breast cancer survivors 3 years after diagnosis.Between April 2002 and March 2004 2,232 women with breast cancer were recruited into the Shanghai Breast Cancer Survival Study, a population-based cohort study, approximately 6 months after cancer diagnosis. QOL was evaluated at 6 and 36 months post-diagnosis using the General Quality of Life Inventory. Multiple linear regression models were used to evaluate changes in QOL and their associations with socio-demographic and medical factors.In general, breast cancer patients showed significant improvement over time in the physical, psychological, and social well-being domains, as well as overall QOL. However, QOL scores in several facets did not improve or even deteriorated, including increased negative feelings, reduced social support and interpersonal relationships, and worsened financial situation and living environment. Age at diagnosis was inversely associated with QOL changes in physical and psychological well-being and overall QOL scores. Compared with those who were disease-free, patients with a recurrence of disease had significantly poorer QOL scores across all well-being domains and almost all facets. Patients who received radiotherapy experienced significant improvements in physical and social well-being and overall QOL. Mixed ER/PR status was associated with improved scores in physical and psychological well-being and overall QOL. Education, body mass index, Charlson comorbidity score, TNM stage, type of surgery, chemotherapy, and immunotherapy were only associated with changes in certain well-being domains and/or facets, but not overall QOL. Tamoxifen use was not associated with changes in QOL outcomes.Our study provides valuable information for developing strategies/interventions for improving the QOL of breast cancer patients.",
        "keywords": [
            "and medical factors",
            "breast cancer chinese women changes in quality of life",
            "socio-demographic",
            "cohort study",
            "breast cancer",
            "interpersonal relationship",
            "quality of life",
            "psychological well being",
            "multiple linear regression"
        ],
        "authors": [
            {
                "name": "Wei Lu",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Yong Cui",
                "org": "Vanderbilt University Medical Center Department of Medicine, Vanderbilt Epidemiology Center 2525 West End Avenue, Suite 600 Nashville TN 37203-1738 USA"
            },
            {
                "name": "Xiaoli Chen",
                "org": "Vanderbilt University Medical Center Department of Medicine, Vanderbilt Epidemiology Center 2525 West End Avenue, Suite 600 Nashville TN 37203-1738 USA"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Center for Disease Control and Prevention Shanghai 200336 China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University Medical Center Department of Medicine, Vanderbilt Epidemiology Center 2525 West End Avenue, Suite 600 Nashville TN 37203-1738 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University Medical Center Department of Medicine, Vanderbilt Epidemiology Center 2525 West End Avenue, Suite 600 Nashville TN 37203-1738 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University Medical Center Department of Medicine, Vanderbilt Epidemiology Center 2525 West End Avenue, Suite 600 Nashville TN 37203-1738 USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2009
    },
    "ib1XKI5S": {
        "id": "ib1XKI5S",
        "title": "Prospective evaluation of type 2 diabetes mellitus on the risk of primary liver cancer in chinese men and women",
        "abstract": "Background: No prospective study has investigated the relationship between type 2 diabetes mellitus (T2DM) and the risk of primary liver cancer (PLC) in mainland China, and little is known about the effect of diabetes duration on PLC risk. Design: Data from two population-based cohorts (the Shanghai Men's Health Study, SMHS, 2002-2006 and the Shanghai Women's Health Study, SWHS, 1996-2000) were thus used to assess the associations among T2DM, diabetes duration and PLC risk in Chinese population. Results: During follow-up through 2009, 344 incident PLC cases were identified among 60 183 men and 73 105 women. T2DM is significantly associated with the increased risk of PLC in both men [hazard ratio (HR) = 1.63, 95% confidence interval (CI) 1.06-2.51] and women (HR = 1.64, 95% CI 1.03-2.61). The highest risk of incident liver cancer was observed in the first 5 years after diabetes diagnosis, and decreased substantially with the prolonged diabetes duration (P-trend < 0.001). No synergistic interaction in the development of PLC was found between diabetes and other known risk factors. Conclusions: T2DM is associated with the increased risk of subsequent liver cancer within 5 years after diagnosis in Chinese population, suggesting that hyperinsulinaemia rather than hyperglycaemia is more likely to be a primary mediator for this association.",
        "keywords": [
            "China",
            "cohort study",
            "primary liver cancer",
            "type 2 diabetes"
        ],
        "authors": [
            {
                "name": "Wanshui Yang",
                "org": "Department of Epidemiology, School of Public Health, Fudan University, Shanghai"
            },
            {
                "name": "Xiaoou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville"
            },
            {
                "name": "Jing Gao",
                "org": "State Key Laboratory of Oncogene and Related Genes"
            },
            {
                "name": "Honglan Li",
                "org": "State Key Laboratory of Oncogene and Related Genes"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville"
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville"
            },
            {
                "name": "Butian Ji",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, USA"
            },
            {
                "name": "Nathaniel R. Rothman",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, USA"
            },
            {
                "name": "Yutang Gao -",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville"
            },
            {
                "name": "Yongbing Xiang",
                "org": "State Key Laboratory of Oncogene and Related Genes"
            }
        ],
        "venue": "Annals of Oncology",
        "year": 2013
    },
    "WuCFveDu": {
        "id": "WuCFveDu",
        "title": "Environmental stability of 2D anisotropic tellurium containing nanomaterials: anisotropic to isotropic transition.",
        "abstract": "We report on the vibrational (Raman) spectrum and structural transformation of semiconducting pseudo-1D GaTe and ZrTe3 nanomaterials driven by ambient molecular interactions at the nanoscale by angle-resolved Raman spectroscopy, atomic force microscopy (AFM), and environmental X-ray photoelectron (XPS) measurements. The results show that tellurium containing pseudo-1D materials undergo drastic structural and physical changes within a week. During this process, new Raman peaks start to emerge and surface roughness increases substantially. Surprisingly, aged Raman spectra of GaTe, ZrTe3, and alpha-TeOx show striking similarities suggesting that oxidation of tellurium takes place. Careful, environmental tests reveal that the interaction between GaTe and H2O molecules forms Te-O bonds at the outermost layers of GaTe which leads to newly emerging Raman peaks, a much reduced Schottky junction current density, and an anisotropic to isotropic structural transition. These findings offer fresh interpretation of the aging mechanisms for these material systems, provide new interpretation of the Raman spectrum of aged GaTe which was previously presumed to be of the hexagonal phase, and introduce an anisotropic to isotropic transformation effect induced by molecular interactions on the surface.",
        "keywords": "",
        "authors": [
            {
                "name": "Sijie Yang",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Changhyun Ko",
                "org": "Sookmyung Womens Univ, Coll Engn, Dept Appl Phys, Seoul 04310, South Korea"
            },
            {
                "name": "V Ongun Özçelik",
                "org": "Princeton Univ, Dept Civil & Environm Engn, Princeton, NJ 08544 USA"
            },
            {
                "name": "D Frank Ogletree",
                "org": "Lawrence Berkeley Natl Lab, Mol Foundry, Berkeley, CA 94720 USA"
            },
            {
                "name": "Claire E White",
                "org": "Princeton Univ, Dept Civil & Environm Engn, Princeton, NJ 08544 USA"
            },
            {
                "name": "Yuxia Shen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "NANOSCALE",
        "year": 2017
    },
    "quGfLtgU": {
        "id": "quGfLtgU",
        "title": "Dietary iron intake and risk of endometrial cancer: a population-based case-control study in Shanghai, China.",
        "abstract": "Dietary red meat and animal fat have been linked to endometrial cancer (EC) risk, but the impact of bioavailable iron in animal-derived foods has been less well studied. Our objective was to investigate the effects of iron and fats on the risk of EC in a large, population-based, case-control study. The Shanghai Endometrial Cancer Study enrolled 1,204 EC cases and 1,212 controls who completed in-person interviews, including a food frequency questionnaire. Animal-derived iron and fat intakes were calculated from dietary intakes and food composition tables. Logistic regression models were used to evaluate independent and joint effects of iron and fat on EC risk. Animal-derived iron intake was positively associated with EC risk [adjusted OR = 1.9; 95% CI = 1.4-2.7, P(trend) < 0.01, highest vs. lowest quartile], predominantly after menopause (OR = 2.2; 95%CI = 1.4-3.4, P(trend) < 0.01) and in women with BMI >or= 25 kg/m(2)(OR = 3.2; 95% CI = 1.4-7.5 in postmenopausal obese women, P(trend) < 0.01). Animal-derived fat was also associated with postmenopausal EC risk (OR = 1.7; 95% CI = 1.2-2.5, P(trend) < 0.01). Multiplicative interactions between animal-derived iron and BMI or animal-derived fat intake were not observed. Animal-derived iron intake is associated with increased risk of EC after menopause and among obese women. Avoidance of animal-derived (heme) iron may reduce the risk of EC in these women.",
        "keywords": [
            "case control study",
            "logistic regression model",
            "iron"
        ],
        "authors": [
            {
                "name": "Asha R Kallianpur",
                "org": ""
            },
            {
                "name": "Sang-Ah Lee",
                "org": ""
            },
            {
                "name": "Wang-Hong Xu",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Zhi-Xian Ruan",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            }
        ],
        "venue": "Nutrition and cancer",
        "year": 2010
    },
    "EPz2C0vZ": {
        "id": "EPz2C0vZ",
        "title": "A Prospective Study of Dietary Polyunsaturated Fatty Acids Intake and Lung Cancer Risk.",
        "abstract": "Animal studies have shown that polyunsaturated fatty acids (PUFAs) have antineoplastic and anti-inflammatory properties. Results from epidemiologic studies on specific types of PUFAs for lung cancer risk, however, are inconclusive. We prospectively evaluated the association of specific types of dietary PUFA intakes and lung cancer risk in two population-based cohort studies, the Shanghai Women's Health Study (SWHS) and Shanghai Men's Health Study (SMHS) with a total of 121,970 study participants (i.e., 65,076 women and 56,894 men). Dietary fatty acid intakes were derived from data collected at the baseline using validated food frequency questionnaires (FFQs). Cox proportional hazards model was performed to assess the association between PUFAs and lung cancer risk. Total, saturated and monounsaturated fatty acid intakes were not significantly associated with lung cancer risk. Total PUFAs intake was inversely associated with lung cancer risk [HRs and respective 95% CIs for quintiles 2 to 5 versus quintile 1: 0.84 (0.71-0.98), 0.97 (0.83-1.13), 0.86 (0.74-1.01) and 0.85 (0.73-1.00), P =0.11]. However, DHA intake was positively associated with lung cancer risk [HRs and 95% CIs: 1.01 (0.86-1.19), 1.20 (1.03-1.41), 1.21 (1.03-1.42) and 1.24 (1.05-1.47), P =0.001]. The ratio of n-6 PUFAs to n-3 PUFAs (i.e., 7:1) was inversely associated with lung cancer risk, particularly among never-smokers and adenocarcinoma patients. Total PUFAs and the ratio between n-6 PUFAs and n-3 PUFAs were inversely associated with lung cancer risk. Our current study highlights an important public health impact of PUFA intakes toward intervention/prevention programs of lung cancer. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "Polyunsaturated fatty acids",
            "lung cancer risk"
        ],
        "authors": [
            {
                "name": "Hung N Luu",
                "org": "Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Harvey J Murff",
                "org": "Tennessee Valley Healthcare System, Veterans Affairs Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Qiuyin Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Jing Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Gong Yang",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Qing Lan",
                "org": "Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute (NCI), Bethesda, MD, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            }
        ],
        "venue": "International journal of cancer",
        "year": 2018
    },
    "LRAH2RVZ": {
        "id": "LRAH2RVZ",
        "title": "Original dance drama Shanghai Beauty sold 50%of the house already",
        "abstract": "OUTLINE/ After almost two years' preparation,the original dance drama Shanghai Beauty,co-produced by the Eastern Shanghai International Culture Film & Television Group and the Shanghai Opera House, started rehearsals by the Shanghai Opera House Dance Troupe on November 29.Three numbers of the show were presented during the opening ceremony.Half of the tickets for its first performances in Shanghai have already been sold, which is truly promising.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            },
            {
                "name": "康骏",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "9ZqnknGZ": {
        "id": "9ZqnknGZ",
        "title": "Abdominal adiposity and mortality in Chinese women. Commentary",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Frank B. Hu",
                "org": ""
            },
            {
                "name": "Xianglan Zhang",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "JAMA Internal Medicine",
        "year": 2007
    },
    "Nv6afgQs": {
        "id": "Nv6afgQs",
        "title": "Effect of total flavonoids of epimedium on plasma BNP in rats with congestive heart failure",
        "abstract": "Objective It is to explore the effect of total flavonoids of epimedium(TFE) on plasma BNP in rats with congestive heart failure(CHF).Methods 80 male SD rats were randomly divided into 5 groups: blank control group,CHF control group,metoprolol group and TFE low-dose(TFE-L)group,TFE medium-dose(TFE-M)group,TFE high-dose(TFE-H)group.At 18th week,the hemodynamic parameters were detected by LV morphopathological examination,the plasma BNP were detected by enzyme immunoassay method,and cardiac muscle was gotten to observe the pathomorphology characteristic.Results Compared with the bland control group,the indexes of heart hemodynamics all get worse,and BNP in the plasma and cardiac ventricle body mass index were significantly increased in CHF control group.Compared with that in CHF control group,the indexes of heart hemodynamics all get worse,and BNP in the plasma and cardiac ventricle body mass index were significantly decreased in every TFE group.Conclusion TFE can improve heart function and low down the plasma BNP of experimental rats with congestive heart failure.",
        "keywords": [
            "metoprolol",
            "congestive heart failure",
            "rats",
            "BNP",
            "Isoproterenol",
            "TFE"
        ],
        "authors": [
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Guo Han",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Jiao Dongdong",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Guo Junhao",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "Cai Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Modern Journal of Integrated Traditional Chinese and Western Medicine",
        "year": 2010
    },
    "UNXjARr5": {
        "id": "UNXjARr5",
        "title": "Acupuncture and Moxibustion Therapy For Obese Patients with Type 2 Diabetes:A Report of 35 Cases",
        "abstract": "Objective: To study the effect of acupuncture and moxibustion therapy on body mass in obese patients with type 2 diabetes mellitus(T2DM).Methods: Thirty-five outpatients with obese T2DM were treated by acupuncture and moxibustion at selected acupoints according to traditional Chinese medicine syndrome.Serum levels of fasting blood sugar(FBS) and fasting insulin(FINS) were measured to calculate insulin sensitivity index(ISI) and homeostasis model assessment-insulin resistance(Homa-IR),and the body mass,height and skinfold thickness were measured to calculate BMI,obesity degree and body fat percentage before and after treatment.Results: Three treatment courses later,serum levels of FBS and FINS,Homa-IR were decreased significantly,while ISI were markedly increased.The total effective rate reached 71%.The body mass,BMI,obesity degree and body fat percentage were decreased significantly.Conclusion: Acupuncture and moxibustion therapy possesses of marked hypoglycemic and slimming effects in treating obese T2DM,and it can ameliorate insulin resistance.",
        "keywords": [
            "Acupuncture and moxibustion",
            "Type 2 diabetes",
            "Slimming",
            "Obese"
        ],
        "authors": [
            {
                "name": "YUAN Ai-hong",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Jiangsu Nanjing ,China"
            },
            {
                "name": "LIU Zhi-cheng",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Jiangsu Nanjing ,China"
            },
            {
                "name": "WEI Qun-li",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2009
    },
    "hgcC5On4": {
        "id": "hgcC5On4",
        "title": "Changes of plasma NE and AngⅡin rats with isoproterenol-induced chronic heart failure",
        "abstract": "Objective To establish a rat model of isoproterenol(ISO)-induced chronic heart failure(CHF),and to observe the changes of plasma NE and angiotensinⅡ(AngⅡ).Methods Male SD rats were randomly assigned into ISO-induced chronic heart failure group(ISO group,n=50)and healthy control group(CON group,n=10).Animals in ISO group received the subcutaneous injections of high dose of ISO(170 mg/kg)twice to establish the model of CHF and those in CON group were subcutaneously injected 0.25 ml of normal saline.18 w later,left ventricular end-diastolic dimension(LVEDD),left ventricular end-systolic dimension(LVESD),interventricular septal thickness(IVST),left ventricular posterior wall thickness(LVPWT),fractional shortening(FS)and left ventricular ejection fraction(LVEF)of both groups were measured by echocardiogram.The levels of plasma NE and AngⅡ were detected by ELISA.In addition,myocardial samples were obtained for the pathologic and morphologic observation.Results Compared with CON group,LVEF and FS decreased,LVEDD and LVESD enlarged and plasma NE and AngⅡincreased significantly in ISO group.Pathological examination showed that the cardiocytes of the animals in ISO group were hypertrophic,parts of them were acidophilic denaturation and/or necrosis,and the desmoplasia was found in myocardial interstitial tissues.Conclusion CHF model of rats can be induced by high dose of isoproterenol.The increased levels of plasma NE and AngⅡ may be involved in the induced roles.",
        "keywords": [
            "myocardial remodeling",
            "chronic heart failure",
            "isoproterenol",
            "angiotensinⅡ"
        ],
        "authors": [
            {
                "name": "Zhao Zhiming",
                "org": " Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Guo Han",
                "org": " Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Guo Junhao",
                "org": " Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Zhao Lingjie",
                "org": " Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu,,China"
            },
            {
                "name": "Cai Hui",
                "org": " Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu,,China"
            }
        ],
        "venue": "Medical Journal of National Defending Forces in Southwest China",
        "year": 2011
    },
    "UDEeRmmA": {
        "id": "UDEeRmmA",
        "title": "Abstract 5310: A prospective study of dietary polyunsaturated fatty acid intakes and lung cancer risk",
        "abstract": "Background. Animal studies have shown that polyunsaturated fatty acids (PUFAs) have antineoplastic and anti-inflammatory properties. Results from epidemiologic studies, however, have been inconclusive. We prospectively evaluated the association of dietary PUFA intakes and lung cancer risk in two population-based cohort studies, the Shanghai Men’s Health Study (SMHS) and Shanghai Women’s Health Study (SWHS).  Methods. A total of 130,823 study participants (i.e., 60,427 men and 70,396 women) were included in the current analysis. Dietary fatty acid intakes were derived from data collected at the baseline by validated food frequency questionnaires. Cox proportional hazards model was applied to assess the association between PUFAs intake and lung cancer risk with adjustment for age, smoking status, smoking packs-year (men only), drinking status, BMI, physical activity status, total energy, red meat intake, vegetable intake, vitamin supplemental use, menopausal status and hormone replacement therapy (women only).  Results. We found an inverse association between total PUFA intakes and lung cancer risk [hazard ratios (HRs) and respective 95% confidence intervals (CIs) for quintiles 2, 3, 4, and 5 versus quintile 1 were 0.73 (0.56-0.95), 0.78 (0.59-1.03), 0.64 (0.47-0.87) and 0.55 (0.37-0.82) in SMHS and 0.69 (0.53-0.90), 0.76 (0.58-0.99), 0.60 (0.44-0.81), and 0.53 (0.36-0.79) in SWHS)]. A similar pattern was observed for consumption of linoleic acid, total n-6 PUFAs and the ratio n-6 PUFAs/n-3 PUFAs in adenocarcinoma patients. This inverse association was more likely in male ever-smokers for total PUFAs, linoleic acid and total n-6 PUFAs. On the other hand, EPA intake was positively associated with lung cancer risk in female never-smokers [HRs and 95% CIs: 1.10 (0.85-1.42), 1.36 (1.05-1.77), 1.28 (0.97-1.88) and 1.30 (0.97-1.74), for quintiles 2-5 versus quintile 1]. A similar positive association between DHA intake and lung cancer risk in female never-smokers was also observed.  Conclusions. Total polyunsaturated fatty acid, linoleic and total n-6 PUFA intakes were associated with decreased risk of lung cancer. EPA and DHA intakes were associated with an increased risk of lung cancer among female never-smokers.  Financial Support: This work was supported by grants from the US National Institutes of Health/National Cancer Institute (R37 CA070867 and UM1 CA182910 - to Wei Zheng; R01 CA082729, UM1 CA173640 and R25 CA160056 - to Xiao-Ou Shu)   Citation Format:  Hung N. Luu, Harvey J. Murff, Honglan Li, Qiuyin Cai, Yu-Tang Gao, Jing Gao, Hui Cai, Gong Yang, Qing Lan, Yong-Bing Xiang, Wei Zheng, Xiao-Ou Shu. A prospective study of dietary polyunsaturated fatty acid intakes and lung cancer risk [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5310. doi:10.1158/1538-7445.AM2017-5310",
        "keywords": "",
        "authors": [
            {
                "name": "Hung N. Luu",
                "org": "University of South Florida, Tampa, FL;"
            },
            {
                "name": "Harvey J. Murff",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Cancer Institute, Shanghai, China;"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute, Shanghai, China;"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Cancer Institute, Shanghai, China;"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Qing Lan",
                "org": "National Cancer Institute, Bethesda, MD."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Cancer Institute, Shanghai, China;"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University, Nashville, TN;"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University, Nashville, TN;"
            }
        ],
        "venue": "Cancer Research",
        "year": 2017
    },
    "JRNvCTO0": {
        "id": "JRNvCTO0",
        "title": "Influence of Pioglitazone on the Expression of Adipor on Aortic in Hyperlipidemia Rats",
        "abstract": "Objective To observe the expression of AdipoR on the aorta in hyperlipidemia rats,and to investigate the influence of pioglitazone on the expression of AdipoR on aortic in hyperlipidemia rats,and the possible mechanism of anti-atherosclerosis.Methods 26 male SD rats were randomly divided into the high-fat diet group(17)and control group(9).high-fat diet group was fed with hypercholesterol diet for 12 weeks,then the serum lipid level was measured in the all rats,and to know whether the model of rats with hyperlipidemia was constructed by feeding hypercholesterol diet,then 17 male SD rats were randomly devided into two groups:model group,high hyperlipidemia with pioglitazone group.By intragastric administration,pioglitazone group rats were given pioglitazone(0.6mg/ml)for four weeks,then the serum lipid levels of all rats were measured and the aorta was taken for pathologic analysis.Serum adiponectin was detected by ELISA.AdipoR was measured by Western Bolt and reverse transcription polymerise chain reaction(RT-PCR).Results After 12 weeks of feeding,compared with control group,the high-fat diet group show significantly higher levels of total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C)(P<0.01).After 4 weeks' treatment,as compared with the model group,the level of TC,TG in the pioglitazone group was obviously lower(P< 0.01),the level serum of adiponectin was significantly increased(P<0.05),and the mRNA expression of both AdipoR1(P<0.05)and AdipoR2(P<0.01)were significantly increased,and the protein expression of both AdipoR1 and AdipoR2 were significantly increased(P<0.05).Conclusion Dcreased adiponectin and its receptors may be involved in vascular impairment in rats with high-fat diet induced hyperlipidemia.Pioglitazone has anti-atherosclerotic effect,the effect may be related to increased serum adiponectin and vascular expression of adiponectin receptor.",
        "keywords": [
            "AdipoR1and AdipoR2",
            "Pioglitazone",
            "Hyperlipidemia",
            "Adiponectin",
            "Aortic"
        ],
        "authors": [
            {
                "name": "XU Yu-shun",
                "org": ".School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".School of Clincal Medicine,Southern Medical University·Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Molecular Cardiology of China",
        "year": 2010
    },
    "Fq1kQZBD": {
        "id": "Fq1kQZBD",
        "title": "Distribution of bone mineral density in dual femur of human being",
        "abstract": "Objective Research for dual femur bone mineral density(BMD) distribution of human being,in order to provide an evidence of how to choose the region of interest.Methods Dual femur BMD of subjects were detected by double-energy X-ray absorptiometry(GE Lunar Prodigy).Femur neck and the total hip were selected as region of interest.Results 301 subjects were detected,135 were male,whose BMD differences of left and right side of femur neck were(0.004±0.048)g/cm2,while those of the total hip were(0.006±0.042)g/cm2,not statistically significant.The differences between the higher density and the lower density of femur neck were(0.038±0.029)g/cm2[95%CI(0.034,0.043)],while those of the total hip were(0.035±0.025)g/cm2[95%CI(0.030,0.039)].166 were female,whose BMD differences of left and right side of femur neck were(0.006±0.040)g/cm2,while those of the total hip were(0.003±0.036)g/cm2,not statistically significant.The differences between the higher density and the lower density of femur neck were(0.032±0.025)g/cm2[95%CI(0.028,0.036)],while those of the total hip were(0.030±0.021)g/cm2[95%CI(0.027,0.033)].In both men and women,the BMD of the femur neck and the total hip have a positive correlation.Conclusion BMD distributions of human being of the region of interest in both left and right hip is almost conformity,but because of the ascendant side exist,detecting both side of hip is suggested and the lower side should be reported as the BMD.",
        "keywords": [
            "Bone mineral density",
            "Osteoporosis",
            "Dual-energy X-ray absorptiometry",
            "Hip"
        ],
        "authors": [
            {
                "name": "GUO Junhao",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Osteoporosis",
        "year": 2009
    },
    "kxbSKhq1": {
        "id": "kxbSKhq1",
        "title": "Effect of pioglitazone on aortic endothelial cell apoptosis in hyperlipidemic rats",
        "abstract": "Objective To investigate the influence of pioglitazone on aortic endothelial cell apoptosis in hyperlipidemia rats and its possible mechanism. Methods A total of 26 male SD rats were randomly divided into control group(n=9) and high-fat diet group(n=17).Rats at high-fat diet group raised for 12 weeks were randomly devided into model group(n=8) and pioglitazone treatment group(n=9).After 4 weeks,serum lipid level of all rats was measured and apoptosis protein expression of Bax and Bcl-2 on the aorta was analyzed by immunohistochemical method.Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling was used to observe apoptotic cells in aortic intimal area and to calculate apoptosis index. Results(1) Serum levels of TG and TC were significantly higher in model group and pioglitazone treatment group than in control group.Serum levels of TG and TC were significantly decreased in pioglitazone treatment group than in model group(P=0.000).(2) Compared with control group,the expression of Bax protein on aorta was significantly increased(P=0.003) and the Bcl-2 protein and ratio of Bcl-2/Bax were markedly decreased in model group(P=0.001 and 0.000,respectively).The expression of Bax protein was significantly lower and Bcl-2 protein and ratio of Bcl-2/Bax were significantly higher in pioglitazone treatment group than in model group,and apoptotic index of aortic intima was significantly lower than in model group[(17.5633±7.0584) vs.(6.0475±2.2370),P=0.000]. Conclusions Pioglitazone can regulate the expression of apoptosis protein Bax and Bcl-2 in aorta and reduce aortic endothelial cell apoptosis in hyperlipidemia rats.",
        "keywords": [
            "Atherosclerosis",
            "Endothelial cells",
            "Apoptosis",
            "Pioglitazone",
            "Hyperlipidemia"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": ".School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ".School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": ".School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Cardiovascular Medicine",
        "year": 2012
    },
    "whlFkXGv": {
        "id": "whlFkXGv",
        "title": "Roles of integrin and vascular endothelial growth factor in angiogenesis",
        "abstract": "Integrin is a main factor that mediates adhesive attraction between the cell and the extracellular matrix,and it participates in the formation of new vessel lumens and the construction of the rete vasculosum by regulating endothelial cell adhesion and migration.The extracellular matrix is the ligand of integrin.Collagen and laminin's deposition form new vessel lumens.The vascular endothelial growth factor promotes the proliferation of endothelial cells,accelerates angiogenesis and increases the permeability of blood vessels.This review focuses on the roles and correlation of integrin and VEGF in angiogenesis.",
        "keywords": [
            "Vascular endothelial growth factor",
            "Angiogenesis",
            "Integrin"
        ],
        "authors": [
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "nybEI06K": {
        "id": "nybEI06K",
        "title": "Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium.",
        "abstract": "Diabetes was associated with a 26% increased risk of death from any cancer in Asians. The pattern of associations with specific cancers suggests the need for better control (prevention, detection, management) of the growing epidemic of diabetes (as well as obesity), in order to reduce cancer mortality.",
        "keywords": [
            "Asia Cohort Consortium",
            "Asians",
            "Cancer mortality",
            "Meta-analysis",
            "Type 2 diabetes"
        ],
        "authors": [
            {
                "name": "Yu Chen",
                "org": "Department of Environmental Medicine, New York University School of Medicine, Tuxedo Park, NY, 10987, USA. yu.chen@nyumc.org."
            },
            {
                "name": "Fen Wu",
                "org": "Department of Environmental Medicine, New York University School of Medicine, Tuxedo Park, NY, 10987, USA."
            },
            {
                "name": "Eiko Saito",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Yingsong Lin",
                "org": "Department of Public Health, Aichi Medical University School of Medicine, Nagakute, Japan."
            },
            {
                "name": "Minkyo Song",
                "org": "Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA."
            },
            {
                "name": "Hung N Luu",
                "org": "Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, USA."
            },
            {
                "name": "Prakash C Gupta",
                "org": "Healis Sekhsaria Institute for Public Health, Navi Mumbai, India."
            },
            {
                "name": "Norie Sawada",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Akiko Tamakoshi",
                "org": "Graduate School of Medicine, Hokkaido University, Sapporo, Japan."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Woon-Puay Koh",
                "org": "Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, People's Republic of China."
            },
            {
                "name": "Yasutake Tomata",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Kemmyo Sugiyama",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Sue K Park",
                "org": "Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Keitaro Matsuo",
                "org": "Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan."
            },
            {
                "name": "Chisato Nagata",
                "org": "Graduate School of Medicine, Gifu University, Gifu, Japan."
            },
            {
                "name": "Yumi Sugawara",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "You-Lin Qiao",
                "org": "Cancer Foundation of China, Beijing, People's Republic of China."
            },
            {
                "name": "San-Lin You",
                "org": "Big Data Research Centre, Fu-Jen Catholic University, Taipei, Taiwan."
            },
            {
                "name": "Renwei Wang",
                "org": "University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA."
            },
            {
                "name": "Myung-Hee Shin",
                "org": "Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea."
            },
            {
                "name": "Wen-Harn Pan",
                "org": "Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan."
            },
            {
                "name": "Mangesh S Pednekar",
                "org": "Healis Sekhsaria Institute for Public Health, Navi Mumbai, India."
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Jian-Min Yuan",
                "org": "Division of Cancer Control and Population Science, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute, Shanghai Jiaotong University, Shanghai, People's Republic of China."
            },
            {
                "name": "Ichiro Tsuji",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Seiki Kanemura",
                "org": "Tohoku University Graduate School of Medicine, Miyagi Prefecture, Japan."
            },
            {
                "name": "Hidemi Ito",
                "org": "Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan."
            },
            {
                "name": "Keiko Wada",
                "org": "Graduate School of Medicine, Gifu University, Gifu, Japan."
            },
            {
                "name": "Yoon-Ok Ahn",
                "org": "Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Armed Forces Capital Hospital, Seoul National University College of Medicine, Seoul, South Korea."
            },
            {
                "name": "Habibul Ahsan",
                "org": "Department of Public Health Sciences, University of Chicago, Chicago, IL, USA."
            },
            {
                "name": "Kee Seng Chia",
                "org": "Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Republic of Singapore."
            },
            {
                "name": "Paolo Boffetta",
                "org": "Icahn School of Medicine at Mount Sinai, New York, NY, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA."
            },
            {
                "name": "Manami Inoue",
                "org": "Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan."
            },
            {
                "name": "Daehee Kang",
                "org": "Cancer Research Institute, Seoul National University, Seoul, South Korea."
            },
            {
                "name": "John D Potter",
                "org": "Department of Epidemiology, University of Washington, Seattle, WA, USA."
            }
        ],
        "venue": "Diabetologia",
        "year": 2017
    },
    "1DR3DjXX": {
        "id": "1DR3DjXX",
        "title": "Vitamin supplement use and risk for breast cancer: the Shanghai Breast Cancer Study.",
        "abstract": "The influence of vitamin supplements on breast cancer risk is unclear and the interactive effects of dietary and supplemental sources are unknown. This study investigated (1) the association between self-reported vitamin supplement use (multivitamin, A, B, C, and E) and breast cancer and (2) the combined effect of vitamin supplements in relation to dietary vitamin intakes on breast cancer risk.The Shanghai Breast Cancer Study was a population-based case-control study conducted in Shanghai in 1996-1998 (Phase I) and 2002-2004 (Phase II). Participants were aged 25-64 (Phase I) and 20-70 years (Phase II). The analyses included 3,454 incident breast cancer cases and 3,474 controls. Unconditional logistic regression models were used to determine adjusted odds ratios (ORs) for breast cancer risk associated with vitamin supplement use.Overall, breast cancer risk was not related to any vitamin supplement intake. However, a 20% reduction in breast cancer risk was observed with vitamin E supplement use among women with low-dietary vitamin E intake (OR = 0.8; 95% confidence interval (CI), 0.6-1.0). A non-significant 20% risk reduction was observed among vitamin B supplement users with low B dietary intake (OR = 0.8; 95% CI, 0.6-1.1). Frequent use of a vitamin B supplement was adversely associated with breast cancer risk among those with high dietary vitamin B intake (OR = 1.4; 95% CI: 0.9-2.1; P for interaction = 0.07).This study suggests that vitamins E and B supplements may confer protection against breast cancer among women who have low dietary intake of those vitamins.",
        "keywords": [
            "antioxidants breast cancer dietary supplements epidemiology vitamin a vitamin b vitamin c vitamin e",
            "adjusted odds ratio",
            "interaction effect",
            "risk reduction",
            "breast cancer",
            "confidence interval",
            "case control study",
            "logistic regression model"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            },
            {
                "name": "Martha J Shrubsole",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Institute of Preventive Medicine Shanghai China"
            },
            {
                "name": "Zhixian Ruan",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Institute of Preventive Medicine Shanghai China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            },
            {
                "name": "Qi Dai",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Institute of Preventive Medicine Shanghai China"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Cancer Institute Department of Epidemiology Shanghai China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University Department of Medicine, Vanderbilt Epidemiology Center, School of Medicine Nashville TN USA"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2008
    },
    "pCuCOBqo": {
        "id": "pCuCOBqo",
        "title": "Observation of bosonic condensation in a hybrid monolayer MoSe-GaAs microcavity.",
        "abstract": "Bosonic condensation belongs to the most intriguing phenomena in physics, and was mostly reserved for experiments with ultra-cold quantum gases. More recently, it became accessible in exciton-based solid-state systems at elevated temperatures. Here, we demonstrate bosonic condensation driven by excitons hosted in an atomically thin layer of MoSe2, strongly coupled to light in a solid-state resonator. The structure is operated in the regime of collective strong coupling between a Tamm-plasmon resonance, GaAs quantum well excitons, and two-dimensional excitons confined in the monolayer crystal. Polariton condensation in a monolayer crystal manifests by a superlinear increase of emission intensity from the hybrid polariton mode, its density-dependent blueshift, and a dramatic collapse of the emission linewidth, a hallmark of temporal coherence. Importantly, we observe a significant spin-polarization in the injected polariton condensate, a fingerprint for spin-valley locking in monolayer excitons. Our results pave the way towards highly nonlinear, coherent valleytronic devices and light sources.",
        "keywords": "",
        "authors": [
            {
                "name": "Max Waldherr",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Nils Lundt",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Martin Klaas",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Simon Betzold",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Matthias Wurdack",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Vasilij Baumann",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Eliezer Estrecho",
                "org": "Australian Natl Univ, ARC Ctr Excellence Future Low Energy Elect Techno, Canberra, ACT 2601, Australia"
            },
            {
                "name": "Anton Nalitov",
                "org": "Univ Iceland, Sci Inst, Dunhagi 3, IS-107 Reykjavik, Iceland"
            },
            {
                "name": "Evgenia Cherotchenko",
                "org": "ITMO Univ, St Petersburg 197101, Russia"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Elena A Ostrovskaya",
                "org": "Australian Natl Univ, ARC Ctr Excellence Future Low Energy Elect Techno, Canberra, ACT 2601, Australia"
            },
            {
                "name": "Alexey V Kavokin",
                "org": "Univ Southampton, Phys & Astron Sch, Highfield Campus, Southampton SO17 1BJ, Hants, England"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sebastian Klembt",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Sven Höfling",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            },
            {
                "name": "Christian Schneider",
                "org": "Univ Wurzburg, Tech Phys, D-97074 Wurzburg, Germany"
            }
        ],
        "venue": "NATURE COMMUNICATIONS",
        "year": 2018
    },
    "ziNrON3K": {
        "id": "ziNrON3K",
        "title": "Fruit and vegetable intake and the risk of colorectal cancer: results from the Shanghai Men's Health Study.",
        "abstract": "The observed associations of fruit and vegetable consumption with the risk of colorectal cancer have been inconsistent. Therefore, we aimed to evaluate the association of fruit and vegetable consumption with the risk of colorectal cancer among Chinese men.61,274 male participants aged 40-74 years were included. A validated food frequency questionnaire was administered to collect information on usual dietary intake, including 8 fruits and 38 vegetables commonly consumed by residents of Shanghai. Follow-up for diagnoses of colon or rectal cancer was available through 31 December 2010. Dietary intakes were analyzed both as categorical and continuous variables. Multivariable-adjusted hazard ratios (HRs) and 95 % confidence intervals (95 % CIs) were calculated for colorectal, colon, and rectal cancers using Cox proportional hazards models.After 390,688 person-years of follow-up, 398 cases of colorectal cancer (236 colon and 162 rectal) were observed in the cohort. Fruit consumption was inversely associated with the risk of colorectal cancer (fifth vs. first quintile HR 0.67; 95 % CI 0.48, 0.95; p trend = 0.03), whereas vegetable intake was not significantly associated with risk. The associations for subgroups of fruits and legumes, but not other vegetable categories, were generally inversely associated with the risk of colon and rectal cancers.Fruit intake was generally inversely associated with the risk of colorectal cancer, whereas vegetable consumption was largely unrelated to risk among middle-aged and older Chinese men.",
        "keywords": [
            "vegetables",
            "fruits",
            "colorectal cancer",
            "cohort study",
            "chinese men",
            "proportional hazards models",
            "risk factors",
            "questionnaires",
            "china",
            "cohort studies",
            "multivariate analysis"
        ],
        "authors": [
            {
                "name": "Emily Vogtmann",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Emily B Levitan",
                "org": "University of Alabama at Birmingham(University of Alabama at Birmingham),Birmingham,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "John W Waterbor",
                "org": "University of Alabama at Birmingham(University of Alabama at Birmingham),Birmingham,United States"
            },
            {
                "name": "Jing Gao",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Li Xie",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Qi-Jun Wu",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Bin Zhang",
                "org": "Cincinnati Children's Hospital Medical Center(Children's Hospital Medical Center,Cincinnati Children's Hospital Medical Center),Cincinnati,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Renji Hospital(Shanghai Second Medical University,Renji Hospital),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "Cancer causes & control : CCC",
        "year": 2013
    },
    "HGavKArB": {
        "id": "HGavKArB",
        "title": "Effect of acupuncture on serum leptin level in patients with type II diabetes mellitus]",
        "abstract": "To study the relationship between serum leptin and insulin resistance, and to analyze the effect of acupuncture on serum leptin level in patients with type-II diabetes mellitus (DM).A total of 80 type-II DM patients were randomized into acupuncture and medication groups. Acupuncture was applied to Yishu (EX), Feishu (BL13), Pishu (BL 20), etc. according to syndrome identification. The treatment was given once every other day for 12 weeks. For patients in the medication group, Glibenclamide (2.5-7.5 mg/time, 1-2 times/d according to blood sugar level) was given for 12 weeks. Fasting blood glucose (FBG), fasting insulin (FINS) and fasting leptin (FLP) were detected by using glucose oxidase method, radioimmunoassay and ELISA, respectively. Insulin sensitivity index (ISI) and homeostasis model assessment-insulin resistance (HOMA-IR) were calculated.In comparison with pre-treatment, FBG levels and HOMA-IR in both acupuncture and medication groups, and FINS and FLP levels in the acupuncture group were decreased significantly (P < 0.01), while ISI in both acupuncture and medication groups, and FINS level in the medication group were increased remarkably after the treatment (P < 0.01). Comparison between two groups showed that after the treatment, FINS and FLP levels, and HOMA-IR of the acupuncture group were considerably lower than those of the medication group (P < 0.01), while ISI of the acupuncture group was significantly higher than that of the medication group (P < 0.01).Acupuncture therapy is effective in lowering FLP level, which may contribute to its clinical effect in improving type-II DM.",
        "keywords": [],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Department of Integrated Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, China. njzy_caihui@163.com"
            },
            {
                "name": "Ling-jie Zhao",
                "org": ""
            },
            {
                "name": "Zhi-ming Zhao",
                "org": ""
            },
            {
                "name": "Jun-hao Guo",
                "org": ""
            },
            {
                "name": "Ai-hong Yuan",
                "org": ""
            }
        ],
        "venue": "Zhen ci yan jiu = Acupuncture research / [Zhongguo yi xue ke xue yuan Yi xue qing bao yan jiu suo bian ji]",
        "year": 2011
    },
    "bqn9KGqI": {
        "id": "bqn9KGqI",
        "title": "Novel image registration method based on edge fitting",
        "abstract": "In order to tradeoff the computational efficiency and the stability in image registration, a novel image registration method based on edge features is proposed for image transform estimation. Image edges are extracted by using multi-scale edge detection based on wavelet transform to improve stability. Straight lines are used to fit these edges and every line is assigned a reliability value according to the geometric and gray characteristics. A pair of lines was taken for the basic matching unit. The similar degree between units from different images is computed by Mahalanobis distance method. The registration process is performed by a weighted voting algorithm, each voting holds different weights according to the similar degree between units and the reliability of elemental lines. The experimental result shows that this method is fast, stable and effective in dealing with similar transform (rotation, scale and translation) without any prior knowledge.",
        "keywords": [
            "Edge detection",
            "Edge fitting",
            "Image processing",
            "Image registration",
            "Weighted voting algorithm"
        ],
        "authors": [
            {
                "name": "Hao Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHANG Guang-xin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Guangdianzi Jiguang/Journal of Optoelectronics Laser",
        "year": 2009
    },
    "idpIeFFM": {
        "id": "idpIeFFM",
        "title": "Change of plasma aldosterone in rats with ISO-induced congestive heart failure",
        "abstract": "Objective To establish the animal model of isoproterenol(ISO)-induced congestive heart failure(CHF) in rats and study the changes of serum aldosterone.Methods Male Sprague-Dawley rats were randomly allocated to the ISO-induced chronic heart failure group(ISO group,n=50) treated with two subcutaneous injections of ISO and the healthy control group (CON group,n=10) treated with two subcutaneous injections of normal saline.At the 18th week,the left ventricular end diastolic pressure,left ventricular end diastolic pressure,maximal rate of LV pressure rise/decline and heart rate were assessed.Aldosterone(ALD) in plasma was detected.18 weeks later,the mass ratio of heart ventricle and left ventricle to body was measured.Results Compared with that in CON group,the LVEF,FS significantly decreased and the LVEDD,LVESD in ISO group enlarged notably(P<0.01).The mass ratio of left ventricle to body and the concentration of ALD of ISO group increased distinctly(P<0.01),compared with that of CON group.Conclusion Activation of plasma aldosterone is increased in high-dose isoproterenol-induction rat model of CHF.",
        "keywords": [
            "SD Rats",
            "Myocardial Remodeling",
            "Aldosterone",
            "Congestive heart failure",
            "Isoproterenol"
        ],
        "authors": [
            {
                "name": "GUO Han",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Medical Journal of West China",
        "year": 2010
    },
    "mQlbmcHx": {
        "id": "mQlbmcHx",
        "title": "Analysis on influencing factor of effect for treating postmenopausal osteoporosis with risedronate sodium capsules",
        "abstract": "AIM: To analyze the influencing factor of effect for treating postmenopausal osteoporosis with risedronate sodium capsules.METHODS: This is a randomized double-blind placebo-controlled clinical research.All patients were divided into two groups,trail group and control group.During 12 months,patients of trail group took risedronate sodium capsules orally every morning,patients of control group took placebo orally every morning,and at the same time all patients took calcichew D orally every night.Multiple linear regression analysis on influencing factor of effect including person's age,height,body weight,body mass index,menopause years,and therapeutic method.RESULTS: The therapeutic method was eventually conducted into the regression equation(P<0.05).CONCLUSION: Risedronate sodium capsule is the independent influencing factor for increasing bone mineral density(BMD),and the BMD has annual gain 0.041 g/cm2.",
        "keywords": [
            "multiple linear regression",
            "osteoporosis",
            "bone mineral density",
            "risedronate sodium"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": " Department of Integration of Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": " Department of Integration of Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": " Department of Integration of Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": " Department of Integration of Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2009
    },
    "R23GoxSq": {
        "id": "R23GoxSq",
        "title": "Abstract 4234: Association between educational level and mortality: A pooled analysis of over 694,000 individuals in the Asia Cohort Consortium",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Keming Yang",
                "org": ""
            },
            {
                "name": "Ying Zhang",
                "org": ""
            },
            {
                "name": "Eiko Saito",
                "org": ""
            },
            {
                "name": "Yu Chen",
                "org": ""
            },
            {
                "name": "Prakash C. Gupta",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Akiko Tamakoshi",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Woon-Puay Koh",
                "org": ""
            },
            {
                "name": "Norie Sawada",
                "org": ""
            },
            {
                "name": "Kemmyo Sugiyama",
                "org": ""
            },
            {
                "name": "Yasutake Tomata",
                "org": ""
            },
            {
                "name": "Atsuko Sadakane",
                "org": ""
            },
            {
                "name": "Chisato Nagata",
                "org": ""
            },
            {
                "name": "San-Lin You",
                "org": ""
            },
            {
                "name": "Renwei Wang",
                "org": ""
            },
            {
                "name": "Myung-Hee Shin",
                "org": ""
            },
            {
                "name": "Habibul Ahsan",
                "org": ""
            },
            {
                "name": "Wen-Harn Pan",
                "org": ""
            },
            {
                "name": "Mangesh S. Pednekar",
                "org": ""
            },
            {
                "name": "Jian-Min Yuan",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Shoichiro Tsugane",
                "org": ""
            },
            {
                "name": "Ichiro Tsuji",
                "org": ""
            },
            {
                "name": "Seiki Kanemura",
                "org": ""
            },
            {
                "name": "Keiko Wada",
                "org": ""
            },
            {
                "name": "Yoon-Ok Ahn",
                "org": ""
            },
            {
                "name": "Kotaro Ozasa",
                "org": ""
            },
            {
                "name": "John D. Potter",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Hongmei Nan",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2018
    },
    "tXnQw3t9": {
        "id": "tXnQw3t9",
        "title": "Tanshinone inhibits lysophosphatidic acid-induced cardiac fibroblast proliferation and TGF-β1 production in neonate rats",
        "abstract": "Objective: To investigate the effects of Tanshinone on the proliferation of cardiac fibroblasts(CF) and the production of TGF-β1 induced by lysophosphatidic acid(LPA) in rats. Methods: CF were isolated by trypsin digestion method,their proliferation measured by MTT assay and the changes of TGF-β1 production in the CF examined by enzyme-linked immunosorbent assay(ELISA).Results: The optical density of each group was increased in a time dependent manner.Compared with the LPA group,low-concentration Tanshinone showed a tendency of inhibition on the LPA-induced CF proliferation and TGF-β1 secretion,though neither with statistic significance(P>0.05),while high-concentration decreased TGF-β1 secretion,obviously after 24 hours(P<0.05) and significantly after 72 hours(P<0.01).Conclusion: Tanshinone inhibits the proliferation of CF and the secretion of TGF-β1 in a concentration-dependent manner,probably inhibiting the former by decreasing the latter.",
        "keywords": [
            "Tanshinone",
            "Cardiac fibroblast",
            "TGF-β1",
            "Lysophosphatidic acid"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "XIU Chun-ying",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "T5aCCFcl": {
        "id": "T5aCCFcl",
        "title": "Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.",
        "abstract": "Objective Circulating estrogen levels have been related to the risk of several female cancers. Blood levels of estrogen are controlled by estrogen synthesis enzymes. Genetic variation of estrogen genes thus may influence circulating estrogen levels. We investigated the associations of genetic polymorphisms in CYP19A1, a critical gene involved in estrogen synthesis, with plasma levels of sex hormones among postmenopausal Chinese women. Methods Included in this study were 345 postmenopausal community controls from a population-based case-control study conducted in Shanghai. Fasting blood samples from those women were measured for blood estradiol, estrone, estrone sulfate, and testosterone. A total of 19 genetic polymorphisms in CYP19A1 were genotyped using AB17900 or PCR-restriction fragment length polymorphism methods. Differences in plasma levels of hormones by genotype were examined using variance analysis. Result The geometric means of plasma levels of estradiol, estrone, estrone sulfate, and testosterone were 10.1, 16.8, 969.0, and 202.9 pg/ml, respectively, for this study population. We found that plasma levels of estrone were associated with rs28566535 (P=0.0180), rs730154 (P=0.0141), and rs936306 (P=0.0274) in block 2. In the same block, the haplotype CGCTA was related to level of estrone (P=0.0064). Single nucleotide polymorphism rs1902584 in block 1 was associated with estradiol only in overweight postmenopausal women. No clear association with sex hormones was noted for the other genetic polymorphisms evaluated in the study. Conclusion Single nucleotide polymorphisms in blocks 1 and 2 of the CYP19A1 gene are related to plasma levels of estrogen among postmenopausal Chinese women and may therefore play an important role in the etiology of hormone-related cancers.",
        "keywords": [
            "association",
            "BMI",
            "CYP19A1",
            "genetic polymorphism",
            "sex hormone",
            "synthesis"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Med Ctr, Inst Med & Publ Hlth, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Med Ctr, Inst Med & Publ Hlth, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Kathleen M Egan",
                "org": "Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33682 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Med Ctr, Inst Med & Publ Hlth, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Ji-Rong Long",
                "org": "Vanderbilt Univ, Med Ctr, Inst Med & Publ Hlth, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Med Ctr, Inst Med & Publ Hlth, Vanderbilt Epidemiol Ctr,Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "PHARMACOGENETICS AND GENOMICS",
        "year": 2008
    },
    "r67sfBhK": {
        "id": "r67sfBhK",
        "title": "Expression of myocardial fibrogenic cytokines in rats with pressure overload and effect of Tanshinone ⅡA",
        "abstract": "Objective To observe the influence of fibrogenic cytokines connective tissue growth factor(CTGF) and transforming growth factor-β1(TGF-β1) expression in rat myocardial tissue with pressure overload and explore the protective effects of Tanshinone Ⅱ A(Tan Ⅱ A) on myocardial fibrosis.Methods The SD rats were prepared with abdominal aorta constriction and the abdominal aortas were clipped for 4 weeks.These rats were divided into 4 groups randomly: Sham group,Model group,Tan Ⅱ A group(TanⅡA group,20 mg·kg-1·d-1) and positive captopril group(captopril group,100 mg·kg-1·d-1).At 8 weeks after surgery,ventricular mass index and left ventricular mass index were estimated,in concurrent evaluation of myocardial histology,as well as myocardial hydroxyproline content by ELISA,and immunohistochemistry staining for myocardial CTGF and TGF-β1 protein content.Results(1) Compared with Sham group,cardiac mass index and left ventricular mass index were increased in Model group [(3.23±0.25)mg/g vs.(2.63±0.13)mg/g,(2.75±0.20)mg/g vs.(2.08±0.11)mg/g,both P<0.01];Compared with Model group,these indexes decreased in Tan Ⅱ A group [(2.88±0.20)mg/g vs.(3.23±0.25)mg/g,(2.36±0.20)mg/g vs.(2.75±0.20)mg/g,both P<0.01].(2) Compared with Sham group,myocardial hydroxyproline content was increased in Model group [(758.58±144.95)μg/g vs.(456.95±125.09)μg/g,P<0.01];Compared with Model group,Tan Ⅱ A had significantly reduced myocardial hydroxyproline content [(520.67±140.79)μg/g vs.(758.58±144.95)μg/g,P<0.01].(3) Compared with Sham group,myocardial tissue of CTGF and TGF-β1 protein content were increased in Model group(5.58%±1.15% vs.2.47%±1.49%,5.83%±1.93% vs.1.85%±0.94%,both P<0.01);Compared with Model group,Tan Ⅱ A had significantly reduced the expression of CTGF and TGF-β1(2.65%±0.68% vs.5.58%±1.15%,2.38%±1.23% vs.5.83%±1.93%,both P<0.01).Conclusions Tan Ⅱ A can inhibit cardiac hypertrophy,attenuate myocardial fibrosis,and this effect may be associated with downregulation of the expression of fibrogenic cytokines CTGF and TGF-β1.",
        "keywords": [
            "Tanshinone ⅡA",
            "Myocardial fibrosis",
            "Connective tissue growth factor",
            "Pressure overload",
            "Transforming growth factor-beta1"
        ],
        "authors": [
            {
                "name": "CHANG Wen-jing",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Cardiovascular Medicine",
        "year": 2013
    },
    "vxLFJ6bP": {
        "id": "vxLFJ6bP",
        "title": "Sinomenine relieves oxygen and glucose deprivation-induced microglial activation via inhibition of the SP1/miRNA-183-5p/IκB-α signaling pathway.",
        "abstract": "Studies have shown that the inflammatory activation of miroglia (MG) and nuclear factor kappa B ( NF-κB ) play a dominant role in inflammatory response. Previous studies have shown that sinomenine, an anti-inflammatory agent extracted from Sinomenium acutum, can directly protect neurons against cerebral ischemia injury. However, there are no reports on its effect on ischemia/reperfusion-induced inflammatory activation of MG. In the present study, an in vitro ischemia/reperfusion model was developed with mouse BV-2 microglia cells, a model of oxygen-glucose deprivation/reperfusion (OGD/R), and the inhibitory effect of sinomenine pretreatment on inflammatory activation was confirmed through measurement of inflammatory indicators. Mechanistically, sinomenine suppressed OGD/R-induced inflammatory activation through the SP1/miRNA-183-5p/IκB-α pathway. In conclusion, this study shows that sinomenine effectively inhibits OGD/R-induced inflammatory activation in MG by suppressing the activation of transcription specificity protein 1 (SP 1). This finding is of significance for the clinical use of sinomenine in treating cerebral ischemia/reperfusion injury.",
        "keywords": [
            "Antiinflammation",
            "OGD/R",
            "Microglia",
            "IκB-α",
            "Sinomenine",
            "miRNA-183-5p."
        ],
        "authors": [
            {
                "name": "Feng Qin",
                "org": "The First Clinical Medical College, Nanjing University of Chinese Medicine,Nanjing, Jiangsu 210023, P.R. China."
            },
            {
                "name": "Yang Zhao",
                "org": "Department of Neurology, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing , Jiangsu 210006, P.R. China."
            },
            {
                "name": "Wei Shang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Jinling Hospital, Nanjing, Jiangsu 210002, P.R. China."
            },
            {
                "name": "Zhi-Ming Zhao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Jinling Hospital, Nanjing, Jiangsu 210002, P.R. China."
            },
            {
                "name": "Xin Qian",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Jinling Hospital, Nanjing, Jiangsu 210002, P.R. China."
            },
            {
                "name": "Bei-Bei Zhang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Jinling Hospital, Nanjing, Jiangsu 210002, P.R. China."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Jinling Hospital, Nanjing, Jiangsu 210002, P.R. China."
            }
        ],
        "venue": "Cellular and molecular biology (Noisy-le-Grand, France)",
        "year": 2018
    },
    "wc16Rnl2": {
        "id": "wc16Rnl2",
        "title": "Mitigation of power system forced oscillations based on unified power flow controller",
        "abstract": "Forced oscillations (FOs), or low-frequency oscillations (LFOs) caused by periodic, continuous, small power disturbances, threaten the security and stability of power systems. Flexible AC transmission system (FACTS) devices can effectively mitigate LFOs via stability control. We propose a novel method that mitigates FOs by shifting the resonant frequency. Based on the features of the linearized swing equation of a generator, a resonant frequency shift can be achieved by controlling the synchronous torque coefficient using a unified power flow controller (UPFC). Because of the resonance mechanism, the steady-state response of an FO can be effectively mitigated when the resonant frequency changes from the original one, which was close to the disturbance frequency. The principle is that a change in resonant frequency affects the resonance condition. Simulations are conducted in a single-machine infinite-bus (SMIB) system, and the simulation results verify that the method is straightforward to implement and can significantly mitigate FOs. The controller robustness when the resonant frequency is not accurately estimated is also analyzed in the simulations.",
        "keywords": [
            "Forced oscillations",
            " Flexible AC transmission systems",
            " Unified power flow controller",
            " Stability control"
        ],
        "authors": [
            {
                "name": "Ping Jiang",
                "org": "School of Electrical Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Zikai Fan",
                "org": "School of Electrical Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Shuang Feng",
                "org": "School of Electrical Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Xi Wu",
                "org": "School of Electrical Engineering, Southeast University, Nanjing, China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, China"
            }
        ],
        "venue": "Modern power systems",
        "year": 2018
    },
    "PBkLzeZy": {
        "id": "PBkLzeZy",
        "title": "Influence of Pioglitazone on Bax & Bcl-2 protein expression of aorta in hyperlipidemia rats",
        "abstract": "【Objective】 To investigate the change of apoptosis protein of Bax & Bcl-2 on aorta in hyperlipidemia rats treated with Pioglitazone,and also to study the possible mechanism of Pioglitazone improved endothelium cell.【Methods】 26 male SD rats were randomly divided into control group(n =9) and high-fat diets group(n =17).High-fat diets group raised for 12 weeks were randomly divided into model group(n =8) and Pioglitazone treated group(n =9).After 4 weeks,serum lipid level of all rats was measured and apoptosis protein of Bax & Bcl-2 on the aorta was analyzed by immunohistochemical method,while using HE staining to observe aortic pathological changes.【Results】 High-fat diets group was raised for 12 weeks,the serum lipid level was significantly higher(P <0.01).Intervention with Pioglitazone for 4 weeks,compared with the model group,serem levels of TG,TC was decreased(P <0.01),and aortal endothelial tissue was completed primitively,proliferation of smooth muscle cells were not obviously.To contrast with control group,the expression of Bax protein on aorta was significantly increased(P <0.01),the Bcl-2 protein and ratio of Bcl-2/Bax was markedly decreased in model group(P <0.01).At the same time,the expression of Bax protein was lower and the Bcl-2 protein and ratio of Bcl-2/Bax was prominently higher in the Pioglitazone treated group than model group.【Conclusions】 High-fat diets have an effect on expression of apoptosis protein Bax & Bcl-2 in aorta,in contrast Pioglitazone can regulate the expression of apoptosis protein Bax & Bcl-2 and the ratio of Bcl-2/Bax,protecting endothelial from damage and apoptosis,to improve the process of atherosclerotic pathological formation.",
        "keywords": [
            "endothelial cells",
            "Pioglitazone",
            "apoptosis",
            "hyperlipidemia",
            "atherosclerosis"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,P.R.China"
            },
            {
                "name": "CAI Hui",
                "org": "School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,P.R.China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,P.R.China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,P.R.China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "School of Clinical Medicine,Southern Medical University & Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2012
    },
    "TkBMMX0R": {
        "id": "TkBMMX0R",
        "title": "The Effect of Acupuncture on Serum Adiponectin in Patient with Type 2 Diabetes Mellitus",
        "abstract": "Objective: To study the relationship between adiponectin and type 2 diabetes mellitus,as well as the effect of acupuncture on serum level of adiponectin in patients with type 2 diabetes.Methods: 80 cases were devided randomly into acupunture(AG) and Glibenclamide group(GG).AG was treated with acupuncture according to pattern of syndrome,while GG dose was regulated according to blood sugar.Fasting plasma glucose(FPG),fasting insulin(FINS) and adiponectin(APN) were detected before and after 12 weeks treatment,at the same time insulin sensitivity index(ISI) and homeostasis model assessment-insulin resistance(HOMA-IR) were calculated.Results: After treatment for 12 weeks,FPG and HOMA-IR decreased significantly,ISI increased significantly in both AG and GG,FINS decreased while APN increased markedly only in AG.FINS increased to some extent,while change of APN was not found in GG.Conclusion: Regulation of acupuncture on adiponectin may be one of mechanisms that acupuncture lowering blood sugar,promoting insulin sensetivity and improving insulin resistance of patients with type 2 diabentes mellitus.Glibenclamide has favourable effect on lowering blood sugar,but doesn't influence serum level of adiponectin.",
        "keywords": [
            "type 2 diabetes mellitus",
            "acupuncture",
            "adiponectin",
            "insulin resistance"
        ],
        "authors": [
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2011
    },
    "IdVELM31": {
        "id": "IdVELM31",
        "title": "Circulating 25-hydroxyvitamin D levels in relation to blood pressure parameters and hypertension in the Shanghai Women's and Men's Health Studies.",
        "abstract": "Little is known about the association of circulating 25-hydroxyvitamin D (25(OH) D) and blood pressure (BP) parameters, including systolic and diastolic BP, pulse pressure (PP), mean arterial pressure (MAP) and hypertension in non-Western populations that have not yet been exposed to foods fortified with vitamins and seldom use vitamin D supplements. A cross-sectional analysis of plasma 25(OH) D levels in association with BP measures was performed for 1460 participants (1055 women and 405 men, aged 40-74 years) of two large cohort studies in Shanghai. Multivariable linear and logistic regressions were conducted. Overall, the prevalence of vitamin D deficiency was 55.8% using National Health and Nutrition Examination Survey, USA criteria and 29.9% using WHO criteria. The median plasma 25(OH)D level in the population was 38.0 nmol/l for men and 33.6 nmol/l for women (P<0.01) among participants who were not on antihypertensive drugs. Among men, BP parameters (systolic BP, diastolic BP and MAP) were significantly and inversely associated with higher quintiles of 25(OH)D compared with the lowest quintile (P-trend < 0.05 for all). Vitamin D non-deficient status (WHO criteria) was inversely associated with hypertension (ORadjusted = 0.29; 95% CI 0.10, 0.82). An inverse association was also found between hypertension and the highest quintile of 25(OH)D (ORadjusted = 0.16; 95% CI 0.04, 0.65 for >= 50.6 nmol/l; Ptrend 0.02). Among women, no significant associations were found for BP parameters and hypertension. The present study shows that vitamin D deficiency is common among adults in urban China. Circulating 25(OH)D levels were inversely related to the levels of individual BP parameters and hypertension among middle-aged and elderly men but not among women. More research is needed to investigate the potential sex differential associations.",
        "keywords": [
            "Blood pressure parameters",
            "Hypertension",
            "25-Hydroxyvitamin D",
            "Sex differences",
            "China"
        ],
        "authors": [
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai 200032, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, IMPH, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "BRITISH JOURNAL OF NUTRITION",
        "year": 2012
    },
    "gINFvkt0": {
        "id": "gINFvkt0",
        "title": "CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "michael k ameriks",
                "org": ""
            },
            {
                "name": "frank u axe",
                "org": ""
            },
            {
                "name": "james p edwards",
                "org": ""
            },
            {
                "name": "cheryl a grice",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "elizabeth ann gleason",
                "org": ""
            },
            {
                "name": "steven p meduna",
                "org": ""
            },
            {
                "name": "kevin l tays",
                "org": ""
            },
            {
                "name": "john j m wiener",
                "org": ""
            },
            {
                "name": "alvah t wickboldt",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2008
    },
    "LCePsXJZ": {
        "id": "LCePsXJZ",
        "title": "Two years follow-up of Panax Notoginseng Saponins combined with DMARDs on treating rheumatoid arthritis",
        "abstract": "Objective Rheumatoid arthritis(RA) is a chronic autoimmune disease characterized by inflammation of joints with cartilage and bone destruction which finally leads to progressive disability.While the cause of RA is still unknown and the disease cannot be cured,conventional disease modifying antirheumatic drugs and biological are effective treatments for many patients.However,new therapies particular Chinese medicine are needed in order to achieve better relief from RA symptoms and to fully prevent joint damage.The aim of this study is to observe the clinical effect and long-term efficiency of Panax Notoginseng Saponins(PNS) combined with methotrexate(MTX) and salicylazosulfapyridine(SASP) in long-term treatment of rheumatoid arthritis(RA).Methods 32 cases of RA were enrolled and treated with PNS combined with MTX and SASP.All patients took PNS at 280 mg iv gtt,qd,14 days was a course and two course every six months,MTX 10 mg po once a week,SASP 0.75g po tid,duration of follow up was 24 months.Curative effect,adverse effects,immunization changes were observed.Results Indexes of joint pain,joint tenderness,joint swelling,Erythrocyte Sedimentation Rate(ESR),the specific indicators of C reactive protein(CRP) and rheumatoid factor changes were statistically significant compared with pretherapy(P<0.05 or P<0.01).Conclusion MTX associated with MTX and SASP can significantly improve the clinical symptoms and signs in long-term treatment of RA.",
        "keywords": [
            "Rheumatoid arthritis",
            "Panax Notoginseng Saponins",
            "Methotrexate",
            "Follow-up"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Region,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2013
    },
    "b6MJZ5hy": {
        "id": "b6MJZ5hy",
        "title": "Puccini's Le Villi at the eve of its China premiere",
        "abstract": "On the evening of May 3~(rd) and 4~(th) 2009,a new production of Puccini's Le Villi will grace the stage in Shanghai.Le Villi is produced by Shanghai Opera House and it is the first ever time it appears on Chinese soil, as part of the Shanghai Spring. David Li has devised a wonderful abstract set for this magical story. For the first time,Shanghai Opera House also auditioned many extras.When the news about the auditions filtered out,there was overwhelming response.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2009
    },
    "yEc0rN0P": {
        "id": "yEc0rN0P",
        "title": "Population-based case-control study of AhR (aryl hydrocarbon receptor) and CYP1A2 polymorphisms and breast cancer risk.",
        "abstract": "The aryl hydrocarbon receptor (AhR) is a key regulator of the transcriptional expression for the cytochrome P450 1 (CYP1) genes. CYP1A2 is one of the major CYP1 enzymes that catalyse 2-hydroxylation of estrogen, a hormone that plays a critical role in the etiology of breast cancer. In this study, we investigated whether two common polymorphisms in these two genes, CYP1A2* 1F and AhR Lys554Arg, were associated with breast cancer risk in 1090 cases and 1183 controls, a subset of the population-based case-control study, the Shanghai Breast Cancer Study. Caffeine tests were performed in vivo in a subset of 236 study subjects to investigate the relationship of these two polymorphisms with CYP1 A2 activity. For the AhR gene, the A (Lys) allele was associated with a decreased risk of breast cancer. Using the genotype GG as reference, odds ratios of 0.82 [95% confidence interval (CI) = 0.69-0.99] for the AG genotype and 0.76 (95% CI = 0.58-1.01) for the AA genotype (P for trend = 0.018) were obtained. However, no association was observed between CYP1A2 genotypes and breast cancer risk, although the CYP1A2* 1F polymorphism was found to be related to CYP1A2 activity. The geometric mean values for the caffeine metabolites ratio were 2.90, 2.30, and 1.95 for CC, AC, and AA genotypes, respectively (P for trend = 0.024). In conclusion, the results from our study suggest that the AhR Lys554Arg polymorphism may be a genetic susceptibility factor for breast cancer, whereas CYP1A2* 1F, which is a potentially functional single nucleotide polymorphism, may not be related to breast cancer risk.",
        "keywords": [
            "AhR",
            "breast cancer",
            "CYP1A2",
            "CYP1A2 activity",
            "SNP"
        ],
        "authors": [
            {
                "name": "Ji-Rong Long",
                "org": ""
            },
            {
                "name": "Kathleen M Egan",
                "org": ""
            },
            {
                "name": "Lisa Dunning",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Qi Dai",
                "org": ""
            },
            {
                "name": "Jordan Holtzman",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "PHARMACOGENETICS AND GENOMICS",
        "year": 2006
    },
    "KRdqTz6q": {
        "id": "KRdqTz6q",
        "title": "Effects of cyclic citrullinated peptide on the proliferation of peripheral blood T cell from rheumatoid arthritis patients",
        "abstract": "Aim To observe activation effects of cyclic citrullinated peptide(CCP) on the peripheral blood T cell of Rheumatoid Arthritis(RA) patients.Methods T cell proliferation of 24 RA patients affected by CCP was detected with CCK-8.16 health volunteers and 24 systemic lupus erythematosus(SLE) were made control groups.All bodies were divided into nine groups,RA blank control group,RA phytohemagglutinin(PHA)control group,RA CCP group,health blank control group,health PHA control group,health CCP group,SLE blank control group,SLE PHA control group,and SLE CCP group.Results After cultured respectively in vitro for 72 h,compared with that of RA blank control group(0.494±0.057),the peripheral blood T cell proliferation of RA PHA control group(0.618±0.068)and RA CCP group(0.699±0.077)obviously increase,and differences have statistical significance respectively(P<0.01,P<0.01).Compared with that of SLE blank control group(0.364±0.061),the peripheral blood T cell proliferation of SLE PHA control group(0.496±0.079)and SLE CCP group(0.451±0.073)obviously increase,and differences have statistical significance respectively(P<0.01,P<0.01).Proliferation extent of RA CCP group(0.205±0.037)increase obviously compared with that of SLE CCP group(0.087±0.018),and differences have statistical significance(P<0.01).Conclusion CCP has specific activation effects on T cell proliferation of RA,and the citrullinated peptide plays an important role in the pathogenesis of RA,suggesting that it is beneficial for treating RA to further interfere with this process.",
        "keywords": [
            "T cell",
            "proliferation",
            "rheumatoid arthritis",
            "cyclic citrullinated peptide"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "YU Wei",
                "org": "PLA Institute of Clinical Laboratory Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu "
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "Cai Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2010
    },
    "cjLpugoG": {
        "id": "cjLpugoG",
        "title": "Genetic Variation in the Peroxisome Proliferator-Activated Receptor (PPAR) and Peroxisome Proliferator-Activated Receptor Gamma Co-activator 1 (PGC1) Gene Families and Type 2 Diabetes: PPAR and PGC1 Gene Families and T2D",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "raquel villegas",
                "org": ""
            },
            {
                "name": "jiajun shi",
                "org": ""
            },
            {
                "name": "jirong long",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "frank hu",
                "org": ""
            },
            {
                "name": "e shyong tai",
                "org": ""
            },
            {
                "name": "chingchu chen",
                "org": ""
            },
            {
                "name": "scott m williams",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            }
        ],
        "venue": "Annals of Human Genetics",
        "year": 2013
    },
    "6zpauBh3": {
        "id": "6zpauBh3",
        "title": "Influence of pioglitazone on lipid levels in experimental model rats of atherosclerosis and its clinical significance",
        "abstract": "Objective To investigate the change of lipid levels in high-fat diets induced atherosclerotic rats treated with pioglitazone, and to explore its clinical significance. Methods Twenty-six male SD rats were randomly divided into control group (n=9) and high-fat diets group (n=17). High-fat diets group received high-fat diets for 12 weeks, and then were randomly devided into model group (n=8) and pioglitazone-treated group (n=9). The control group, model group and pioglitazone-treated group received intragastric administration with distilled water, distilled water (1.5 ml/100 g) and pioglitazone 10 mg/(kg·d) respectively. Meanwhile, all animals continued to receive high-fat diets. After 4 weeks, the serum lipid level of all rats was measured, and the aortic pathological changes were observed. Results Compared with control group, the serum levels of TG, TC in model group and pioglitazone-treated group were significantly higher after 12 weeks' high-fat diets(P<0.01).After intervention with pioglitazone for 4 weeks, the serum levels of TG, TC and LDL-C were decreased (P<0.01). Moreover, the serum levels of TG, TC in pioglitazone-treated group was markedly lower than those in model group(P<0.01). Aortic thickening and smooth muscle cell proliferation were induced in high-fat diets group. Conclusions Pioglitazone can improve lipid levels in hyperlipidemia rats, delay the pathological changes in aortic atherosclerosis, suggesting that the effect of pioglitazone on anti-atherosclerosis may be partly attributed to the improvement of blood lipid.",
        "keywords": [
            "pioglitazone",
            "low density lipoprotein cholestorol",
            "high density lipoprotein cholesterol",
            "triglyceride",
            "atherosclerosis",
            "high-fat diets",
            "cholesterol"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Region of PLA, Nanjing , China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Region of PLA, Nanjing , China"
            },
            {
                "name": "LI Rong",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Region of PLA, Nanjing , China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Region of PLA, Nanjing , China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": ". Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Hospital of Nanjing Military Region of PLA, Nanjing , China"
            }
        ],
        "venue": "Practical Geriatrics",
        "year": 2012
    },
    "UJpWspzw": {
        "id": "UJpWspzw",
        "title": "Effect of Panax Notoginseng Saponins on the Modulating of Proimflammatory Cytokine Productions by Peritoneal Macrophages in Rats with Adjuvant Arthritis",
        "abstract": "Objective To investigate effect of panax notoginseng saponins(PNS)on the modulating of proimflammatory cytokine production by peritoneal macrophages induced by lipopolysaccharide in rats with adjuvant arthritis(AA).Methods Complete Freund's adjuvant was used to induce AA in rats.Productions of tumour necrosis factor(TNF)-α,interleukin-1(IL-1)and IL-6 were determined by radio immunoassay.Results Productions of TNF-α,IL-1 and IL-6 in peritoneal macrophages were significantly increased in adjuvant arthritis compared with normal control.TNF-α was inhibited by PNS in certain concentration ranging from 0.8 to 0.2 mg/ml(P<0.01,P<0.01,P<0.05);IL-1 was all inhibited by PNS(P<0.05);IL-6 was inhibited by PNS only in 0.2 mg/ml.Conclusion PNS has therapeutic effect on AA in rats,which may be related to inhibiting the productions of proimflammatory cytokines of TNF-α,IL-1 and IL-6.",
        "keywords": [
            "Adjuvant arthritis",
            "Panax notoginseng saponins",
            "Cytokines"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "XIU Chun-ying",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Journal of Chinese Microcirculation",
        "year": 2007
    },
    "REg0ED5L": {
        "id": "REg0ED5L",
        "title": "Abstract B88: Plasma carotenoids, tocopherols, retinol and breast cancer risk: Results from the Shanghai Women's Health Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qi dai",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "adrian a franke",
                "org": ""
            },
            {
                "name": "nathaniel rothman",
                "org": ""
            },
            {
                "name": "tsogzolmaa dorjgochoo",
                "org": ""
            },
            {
                "name": "gao yutang",
                "org": ""
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "w h chow",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            }
        ],
        "venue": "Cancer Prevention Research",
        "year": 2008
    },
    "jPm8p0ah": {
        "id": "jPm8p0ah",
        "title": "Diaminopyrimidines, diaminopyridines and diaminopyridazines as histamine H 4 receptor modulators",
        "abstract": "Histamine H4 receptor antagonists.",
        "keywords": [
            "Histamine H4",
            "Antagonists",
            "Pyrimidine",
            "Pyridine",
            "Pyridazine"
        ],
        "authors": [
            {
                "name": "brad m savall",
                "org": "Corresponding author."
            },
            {
                "name": "steven p meduna",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            },
            {
                "name": "kevin l tays",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            },
            {
                "name": "hui cai",
                "org": "Current addresses: WuXi AppTec, San Diego, CA, United States."
            },
            {
                "name": "robin l thurmond",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            },
            {
                "name": "patricia mcgovern",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            },
            {
                "name": "michael david gaul",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            },
            {
                "name": "baoping zhao",
                "org": "Current addresses: WuXi AppTec (WuHan) Co., Ltd, United States."
            },
            {
                "name": "james p edwards",
                "org": "Janssen Pharmaceutical Research & DevelopmentLLC3210 Merryfield RowSan DiegoCA92121United States"
            }
        ],
        "venue": "Bioorganic & Medicinal Chemistry Letters",
        "year": 2015
    },
    "zljpekLI": {
        "id": "zljpekLI",
        "title": "Wagner in China:An interview with the Chinese cast of NCPA's Lohengrin",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "周彭灵子",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2013
    },
    "roaqptnR": {
        "id": "roaqptnR",
        "title": "Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium.",
        "abstract": "The aldehyde dehydrogenase 2 (ALDH2) polymorphism rs671 (Glu504Lys) causes ALDH2 inactivation and adverse acetaldehyde exposure among Asians, but little is known of the association between alcohol consumption and rs671 and ovarian cancer (OvCa) in Asians. We conducted a pooled analysis of Asian ancestry participants in the Ovarian Cancer Association Consortium. We included seven case-control studies and one cohort study comprising 460 invasive OvCa cases, 37 borderline mucinous OvCa and 1274 controls of Asian descent with information on recent alcohol consumption. Pooled odds ratios (OR) with 95% confidence intervals (CI) for OvCa risk associated with alcohol consumption, rs671 and their interaction were estimated using logistic regression models adjusted for potential confounders. No significant association was observed for daily alcohol intake with invasive OvCa (OR comparing any consumption to none=0.83; 95% CI=0.58-1.18) or with individual histotypes. A significant decreased risk was seen for carriers of one or both Lys alleles of rs671 for invasive mucinous OvCa (OR=0.44; 95% CI=0.20-0.97) and for invasive and borderline mucinous tumors combined (OR=0.48; 95% CI=0.26-0.89). No significant interaction was observed between alcohol consumption and rs671 genotypes. In conclusion, self-reported alcohol consumption at the quantities estimated was not associated with OvCa risk among Asians. Because the rs671 Lys allele causes ALDH2 inactivation leading to increased acetaldehyde exposure, the observed inverse genetic association with mucinous ovarian cancer is inferred to mean that alcohol intake may be a risk factor for this histotype. This association will require replication in a larger sample.",
        "keywords": [
            "ALDH2",
            "Asian",
            "drinking habit",
            "ovarian cancer",
            "pooled analysis"
        ],
        "authors": [
            {
                "name": "Tomotaka Ugai",
                "org": "Division of Hematology, Saitama Medical Center Jichi Medical University, Omiya, Saitama, Japan."
            },
            {
                "name": "Linda E Kelemen",
                "org": "Department of Public Health Sciences, College of Medicine and Hollings Cancer Center Medical University of South Carolina, Charleston, SC, USA."
            },
            {
                "name": "Mika Mizuno",
                "org": "Department of Gynecologic Oncology, Aichi Cancer Center Hospital, Nagoya, Japan."
            },
            {
                "name": "Jue-Sheng Ong",
                "org": "Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston, QLD, 4006, Australia."
            },
            {
                "name": "Penelope M Webb",
                "org": "Population Health Department, QIMR Berghofer Medical Research Institute, Herston, QLD, 4006, Australia."
            },
            {
                "name": "Georgia Chenevix-Trench",
                "org": "Genetics and Computational Biology Department, QIMR Berghofer Medical Research Institute, Herston, QLD, 4006, Australia."
            },
            {
                "name": "",
                "org": ""
            },
            {
                "name": "Kristine G Wicklund",
                "org": "Program in Epidemiology, Division of Public Health Sciences Fred Hutchinson Cancer Research Center, Seattle, WA, USA."
            },
            {
                "name": "Jennifer Anne Doherty",
                "org": "Huntsman Cancer Institute Population Health Sciences, University of Utah, UT, USA."
            },
            {
                "name": "Mary Anne Rossing",
                "org": "Department of Epidemiology, University of Washington, Seattle, WA, USA."
            },
            {
                "name": "Pamela J Thompson",
                "org": "Cancer Prevention and Control Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
            },
            {
                "name": "Lynne R Wilkens",
                "org": "Cancer Epidemiology Program, University of Hawaii Cancer Center, Hawaii, USA."
            },
            {
                "name": "Michael E Carney",
                "org": "Department of Obstetrics and Gynecology John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA."
            },
            {
                "name": "Marc T Goodman",
                "org": "Community and Population Health Research Institute Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA."
            },
            {
                "name": "Joellen M Schildkraut",
                "org": "Department of Public Health Sciences, The University of Virginia, Charlottesville, VA, USA."
            },
            {
                "name": "Andrew Berchuck",
                "org": "Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA."
            },
            {
                "name": "Daniel W Cramer",
                "org": "Harvard T. H Chan School of Public Health, Boston, Massachusetts, USA."
            },
            {
                "name": "Kathryn L Terry",
                "org": "Harvard T. H Chan School of Public Health, Boston, Massachusetts, USA."
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA."
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China."
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China."
            },
            {
                "name": "David Van Den Berg",
                "org": "Department of Preventive Medicine, Keck School of Medicine University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA."
            },
            {
                "name": "Malcom C Pike",
                "org": "Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA."
            },
            {
                "name": "Anna H Wu",
                "org": "Department of Preventive Medicine, Keck School of Medicine University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA."
            },
            {
                "name": "Celeste Leigh Pearce",
                "org": "Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA."
            },
            {
                "name": "Keitaro Matsuo",
                "org": "Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan."
            },
            {
                "name": "",
                "org": ""
            }
        ],
        "venue": "CANCER SCIENCE",
        "year": 2018
    },
    "506546Cg": {
        "id": "506546Cg",
        "title": "Polymorphisms of the CYP1B1 gene may be associated with the onset of natural menopause in Chinese women.",
        "abstract": "The Cytochrome P450 1B1 (CYP1B1) is one of the major CYP450 enzymes catalyzing 4-hydroxylation, an important elimination step for estrogens. Relatively little is known, however, about the impact of this gene on the onset and cessation of menstruation, which are the significant milestones in a woman's life and predictors of many hormone related diseases. In this report, we described the association of four SNPs in the CYP1B1 gene, Arg48Gly, Ala119Ser, Leu432Val, and Asp449Asp, with the ages of menarche and menopause, years of menstruation and total number of menstrual cycles. Included in the study were 1958 community controls from two recently completed population-based case-control studies of breast cancer and endometrial cancer. No association was observed between the CYP1B1 polymorphisms and the age of menarche among either pre- or post-menopausal women. Among the women who experienced natural menopause, the three non-synonymous SNPs were significantly associated with menopausal age, years of menstruation, and total number of menstrual cycles. The Gly and Ser alleles of Arg48Gly and Ala119Ser were associated with later menopause, more years of menstruation and more menstrual cycles, while women with allele Val at Leu432Val had a 0.9 year earlier menopause, 1.0 year shorter reproductive span, and 12.6 fewer menstrual cycles than those women without this allele. In conclusion, the results from this study suggested that CYP1B1 genetic polymorphisms may be associated with the natural onset of menopause.",
        "keywords": [
            "CYP1B1",
            "SNP",
            "Age of menarche",
            "Age of menopause"
        ],
        "authors": [
            {
                "name": "Ji-Rong Long",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S-1108 Medical Center North, Nashville, TN 37232-2587, United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S-1108 Medical Center North, Nashville, TN 37232-2587, United States"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S-1108 Medical Center North, Nashville, TN 37232-2587, United States"
            },
            {
                "name": "Hui Cai",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S-1108 Medical Center North, Nashville, TN 37232-2587, United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China"
            },
            {
                "name": "Fan Jin",
                "org": "Department of Epidemiology, Shanghai Cancer Institute, Shanghai 200032, China"
            },
            {
                "name": "Wei Zheng",
                "org": "Department of Medicine and Vanderbilt-Ingram Cancer Center, Vanderbilt University, 1161 21st Avenue South, S-1108 Medical Center North, Nashville, TN 37232-2587, United States"
            }
        ],
        "venue": "Maturitas",
        "year": 2006
    },
    "dTpefDBU": {
        "id": "dTpefDBU",
        "title": "Researched on maximum power point tracking of PV power system",
        "abstract": "To the oscillation and misjudgment problem of the traditional perturbation and observation algorithm, a novel three-point comparison method was proposed. This method applied Constant Voltage Tracking (CVT) method and variable-step perturbation method to solve the problem between tracking accuracy and speed, and applied double-direction perturbation method to make sure the reliability of action to avoid the misjudgment when external conditions fast changing. Restraining the oscillation near the maximum power point effectively was another merit of this proposed method. Finally, the experimental results demonstrate effectiveness of proposed method with PV experimental platform. © (2012) Trans Tech Publications, Switzerland.",
        "keywords": [
            "maximum power point tracking",
            "pv power system",
            "three-point comparison method"
        ],
        "authors": [
            {
                "name": "wei min chen",
                "org": ""
            },
            {
                "name": "shuang chen",
                "org": ""
            },
            {
                "name": "nan xie",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            }
        ],
        "venue": "Applied Mechanics and Materials",
        "year": 2012
    },
    "i0wwBIOB": {
        "id": "i0wwBIOB",
        "title": "Effect of Tanshinone ⅡA on TNF-α expression with pressure overload",
        "abstract": "Objective To observe the expression of TNF-α in rat with pressure overload,and to explore the mechanism of Tanshinone II A(Tan II A) on myocardial fibrosis.Methods Twenty-four Sprague-Dawley(SD) rats induced by the abdominal aorta constriction preparation were randomly assigned into following apporches(n = 8) : Model group,Tan II A group(Tan ⅡA group,20 mg.kg-1.d-1) and positive captopril group(captopril group,100 mg.kg-1.d-1),age matched SD sham operated group(n = 8) as control.The model of pressure overload-induced myocardial fibrosis was successfully established after 4 weeks of operation.After four weeks of Tan IIA treatment,left ventricular mass index,histopathological,myocardial hydroxyproline content,serum tumor necrosis factor-α(TNF-α) were measured.Results Compered with model group,Tan II A can significantly inhibit myocardial pathological changes,reduce cardiac hypertrophy index and myocardial hydroxyproline content,downregulate serum and myocardial tissue of TNF-α protein content(P < 0.01).Conclusions The expression of serum TNF-α protein was significantly increased in pressure overload rat,indicating that proinflammatory cytokine TNF-α plays an important role in myocardial fibrosis;Tan II A can improve cardiac fibrosis,and this effect may be partly associated with downregulation of the expression of proinflammatory cytokine.",
        "keywords": [
            "tumor necrosis factor-α",
            "pressure overload",
            "tanshinone II A",
            "myocardial fibrosis"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing Gerenal Hospital of Nanjing Military Command,PLA,Nanjing,Jangsu ,China"
            },
            {
                "name": "CAI Jia-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing Gerenal Hospital of Nanjing Military Command,PLA,Nanjing,Jangsu ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing Gerenal Hospital of Nanjing Military Command,PLA,Nanjing,Jangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2013
    },
    "ZmBfEoSO": {
        "id": "ZmBfEoSO",
        "title": "Effects of Methotrexate on synovium pathomorphology and expression of nuclear factor-κB in the synovium of adjuvant arthritis rats",
        "abstract": "Objective: Methotrexate(MTX) has an exact curative effect on rheumatoid arthritis(RA),but few studies have been reported on its mechanism.The authors aimed to explore the effects of MTX on the pathomorphology and expression of nuclear factor-κB(NF-κB) in the synovium of adjuvant arthritis(AA) rats by observing the pathological changes of the synovium.Methods: Thirty SD rats induced with Freund complete adjuvant were divided into three groups: normal,model and MTX,the former two groups peritoneally injected with 5% glucose and the latter with MTX 0.3 mg/(kg·d).All the rats were sacrificed after 15 days,their synovium harvested,fixed,embedded,sliced,dyed and observed under the microscope for pathological changes.The expression of NF-κB in the synovium was detected by immunohistochemistry.Results: After H-E staining,the score on synovium pathomorphology was significantly lower in the MTX group than in the model(P<0.05),while the expression of NF-κB in the synovium was markedly increased in the latter group(P<0.05).After MTX treatment,all the indexes above returned to normal(P>0.05).Conclusion: MTX could decrease inflammatory reaction and reduce inflammatory infiltration of the cells in the synovium of AA rats.Its mechanism might be associated with the downregulation of the expression of NF-κB in the synovium.",
        "keywords": [
            "Pathomorphology",
            "Nuclear factor-κB",
            "Adjuvant arthritis",
            "Methotrexate"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHENG Zhao-ling",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "nX27HWUg": {
        "id": "nX27HWUg",
        "title": "CBI-CDPBO1 and CBI-CDPBI1: CC-1065 analogs containing deep-seated modifications in the DNA binding subunit",
        "abstract": "The synthesis and preliminary examination of CBI-CDPBO1 (2) and CBI-CDPBI1(3), CBI analogs of CC-1065 (1) and the duocarmycins incorporating the 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]benzoxazole-7- carboxylate (CDPBO) and 3-carbamoyl-1,2-dihydro-3 H-pyrrolo[3,2-e]benzimidazole-7-carboxyl (CDPBI) DNA binding subunits, are detailed. The agents contain deep-seated modifications in the DNA binding subunits of the natural products with incorporation of a nitrogen capable of functioning as a hydrogen bond acceptor (CDPBO, CDPBI) or hydrogen bond donor (CDPBI) on their inside concave face which is in intimate contact with the minor groove floor. The CDPBO subunit was prepared through use of a novel and effective MnO2- mediated oxidative coupling of 2-(benzyloxy)ethylamine with 5-hydroxyindole (4) to directly provide 2[(benzyloxy)methyl]pyrrolo[3,2-e]benzoxazole (6, 48%) in a reaction cascade that initially proceeds with amine regioselective C4 nucleophilic addition to the in situ generated p-quinone monoimine 13. Subsequent conversion of 6 to 8 (debenzylation; MnO2-NaCN, CH3OH) and selective reduction of the fused pyrrole (Et(3)SiH-CF3CO2H) completed the synthesis of the 1,2-dihydro-3H-pyrrolo[3,2-e]benzoxazole-7-carboxylate ring system. The CDPBI subunit was prepared through selective C4 nitration of 22 followed by reduction of the nitro group and acid-catalyzed closure to the corresponding 2-[(benzyloxy)methyl]pyrrolo[3,2e]benzimidazole 25. The final conversion of 25 to the 1,2-dihydro-3H-pyrrolo[3,2-e]benzimidazole-7-carboxylate ring system (CDPBI) followed the same protocols introduced for CDPBO. The DNA alkylation efficiencies of 2 and 3 were identical and both were substantially diminished relative to that of CBI-CDPI1 (40). Thus, the introduction of a single nitrogen atom in the DNA binding subunit of 40 has a pronounced and detrimental effect on the relative efficiency (100 x) of DNA alkylation. Consistent with these observations, the in vitro cytotoxic activity of (+)-2 and (+)-3 were comparable (IC50 200 pM, L1210) and 40 x less potent than (+)-40 (IC50 = 5 pM, L1210). In contrast to the large impact these small structural changes had on the effrciency of DNA alkylation, the selectivity of DNA alkylation by 2 and 3 was unperturbed and both agents were found to allcylate the same major sites as CBI-CDPI1 (40). The potential origin of these effects is discussed.",
        "keywords": [],
        "authors": [
            {
                "name": "Dale L. Boger",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Weiya Yun",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Hui Cai",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            },
            {
                "name": "Nianhe Han",
                "org": "Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A."
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1995
    },
    "ZrktGrEP": {
        "id": "ZrktGrEP",
        "title": "Effect of acupuncture on insulin resistance in patients with type 2 diabetes mellitus",
        "abstract": "Objective To explore the effect of acupuncture on insulin resistance in patients with type 2 diabetes mellitus.Methods Eighty patients with type 2 diabetes mellitus were divided randomly into acupuncture group and glibenclamide group.The patients in acupuncture group were treated with acupuncture according to pattern of syndrome,while the patients in glibenclamide group were given the corresponding doses of glibenclamide according to the level of blood sugar.Levels of fasting blood sugar(FPG),glycosylated hemoglobin(GHb),fasting insulin(FINS) were detected,and body mass index(BMI),insulin sensitivity index(ISI),homeostasis model assessment-insulin resistance(HOMA-IR) were calculated before and after 12 week treatment.Results Weight,BMI,FPG,GHb,FINS were significantly higher than the normal range both in acupuncture group and glibenclamide group before treatment,and there was no significant deviation between acupuncture group and glibenclamide group(P>0.05).After treatment for 12 weeks,FPG,GHb and HOMA-IR decreased significantly(P<0.01),ISI increased significantly in both acupuncture group and glibenclamide group.Weight,BMI,FINS decreased significantly in acupuncture group(P<0.01),while FINS increased to some extent and no significant changes of weight and BMI were found in glibenclamide group.There was no significant deviation in FPG and GHb between acupuncture group and glibenclamide group after treatment(P>0.05),but the level of FINS in acupuncture group was lower than in glibenclamide group(P<0.01).Conclusion Acupuncture can improve insulin resistance and raise the insulin sensitivity index in patients with type 2 diabetes mellitus by decreasing BMI,FPG,GHb,FINS.",
        "keywords": [
            "acupuncture",
            "type 2 diabetes mellitus",
            "glibenclamide",
            "insulin sensitivity"
        ],
        "authors": [
            {
                "name": "ZHAO Zhi-ming",
                "org": "Dept of Integrative Medicine,Nanjing General Hospital of PLA Nanjing Command,Nanjing ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Dept of Integrative Medicine,Nanjing General Hospital of PLA Nanjing Command,Nanjing ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "Dept of Integrative Medicine,Nanjing General Hospital of PLA Nanjing Command,Nanjing ,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": "Dept of Integrative Medicine,Nanjing General Hospital of PLA Nanjing Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Dept of Integrative Medicine,Nanjing General Hospital of PLA Nanjing Command,Nanjing ,China"
            }
        ],
        "venue": "Journal of Shanxi Medical University",
        "year": 2011
    },
    "vSC8CzXI": {
        "id": "vSC8CzXI",
        "title": "Prospective cohort studies of birth weight and risk of obesity, diabetes, and hypertension in adulthood among the Chinese population: Birth weight and subsequent risk of NCDs",
        "abstract": "Background: Low birth weight (LBW) has been associated with subsequent risks of obesity and certain chronic diseases, but evidence for the associations is limited for the Chinese population. Methods: In this study we analyzed data from two population-based prospective cohort studies, the Shanghai Women's Health Study and the Shanghai Men's Health Study, to examine the associations between LBW and the risk of obesity and chronic diseases. Birth weight was self-reported at baseline; anthropometric measurements were made at study enrollment. Type 2 diabetes mellitus (T2DM) diagnoses were self-reported, whereas hypertension diagnoses were based on self-report and blood pressure measurements at baseline and follow-up surveys. Results: Birth weight was available for 11 515 men and 13 569 women. Non-linear associations were observed for birth weight with baseline body mass index (BMI), waist circumference (WC), waist: hip ratio (WHR), and waist: height ratio (WHtR; P < 0.05 for non-linearity), and LBW was linked with lower BMI, smaller WC, and larger WHR and WHtR. An excess risk of T2DM was observed for LBW (<2500 g) versus birth weight 2500-3499 g since baseline (hazard ratio [HR] 1.17; 95% confidence interval [CI] 0.92-1.49) and since birth (HR 1.29; 95% CI 1.07-1.54), whereas the HRs for hypertension since baseline and birth were 1.13 (95% CI 1.01-1.27) and 1.20 (95% CI 1.11-1.30), respectively. The risk of the diseases decreased as birth weight increased up to similar to 4000 g; further increases in birth weight did not convey additional benefits. Conclusion: The results suggest that LBW, an index of poor intrauterine nutrition, may affect health risks later in life in the Chinese population.",
        "keywords": [
            "birth weight",
            "hypertension",
            "obesity",
            "type 2 diabetes"
        ],
        "authors": [
            {
                "name": "Qinghua Xia",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, State Key Lab Oncogene & Related Genes, Renji Hosp, Shanghai Canc Inst,Sch Med, Shanghai, Peoples R China"
            },
            {
                "name": "Peng Zhou",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiao Tong Univ, State Key Lab Oncogene & Related Genes, Renji Hosp, Shanghai Canc Inst,Sch Med, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yu Jiang",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai, Peoples R China"
            }
        ],
        "venue": "JOURNAL OF DIABETES",
        "year": 2019
    },
    "yOo3buoq": {
        "id": "yOo3buoq",
        "title": "Genetic polymorphisms in the MMP-7 gene and breast cancer survival.",
        "abstract": "Matrix metalloproteinase-7 (MMP-7) is a small secreted proteolytic enzyme with broad substrate specificity. Its expression has been shown to be associated with tumor invasion, metastasis and survival for a variety of cancers. We systematically evaluated single nucleotide polymorphisms (SNPs) in MMP-7 in relation to breast cancer survival in a large follow-up study. Included were 1,079 breast cancer cases that were recruited from 1996 to 1998 and followed for a median of 7.1 years as part of the Shanghai Breast Cancer Study (SBCS). Eleven SNPs, including 2 known functional promoter SNPs, were analyzed using the Affymetrix Targeted Genotyping System. Associations with survival were evaluated by Cox proportional hazards regression and Kaplan-Meier functions. Statistically significant associations with disease-free and/or overall survival (OS) were found for 5 polymorphisms; these associations were explained primarily by 2 SNPs (rs11568818 and rs11225297) that were in high linkage disequilibrium (LD) with the others. Patients homozygous for the rs11568818 rare allele (G) had a significantly worse prognosis (OS HR: 6.7, 95% CI: 2.4-18.6) than patients homozygous for the common allele (A). Significantly improved survival was seen for patients with the rs11225297 T allele, and this association occurred in a dose-response manner; patients with AT (OS HR: 0.7, 95% CI: 0.5-0.9) and TT (OS HR: 0.3, 95% CI: 0.1-0.8) fared better than patients with AA (p-value for trend: 0.001). Thus, common MMP-7 genetic polymorphisms were found to be significant determinants of survival among Chinese women with breast cancer.",
        "keywords": [
            "breast cancer prognosis",
            "mmp-7",
            "snps",
            "breast cancer",
            "alleles",
            "linkage disequilibrium",
            "proportional hazards models"
        ],
        "authors": [
            {
                "name": "Alicia Beeghly-Fadiel",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Chun Li",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "International journal of cancer. Journal international du cancer",
        "year": 2009
    },
    "ye0m4Jan": {
        "id": "ye0m4Jan",
        "title": "Phase Transition across Anisotropic NbS 3 and Direct Gap Semiconductor TiS 3 at Nominal Titanium Alloying Limit.",
        "abstract": "Alloying selected layered transitional metal trichalcogenides (TMTCs) with unique chain-like structures offers the opportunities for structural, optical, and electrical engineering thus expands the regime of this class of pseudo-one-dimensional materials. Here, the novel phase transition in anisotropic Nb(1-x)TixS3 alloys is demonstrated for the first time. Results show that Nb(1-x)TixS3 can be fully alloyed across the entire composition range from triclinic-phase NbS3 to monoclinic-phase TiS3. Surprisingly, incorporation of a small concentration of Ti (x approximate to 0.05-0.18) into NbS3 host matrix is sufficient to induce triclinic to monoclinic transition. Theoretical studies suggest that Ti atoms effectively introduce hole doping, thus rapidly decreases the total energy of monoclinic phase and induces the phase transition. When alloyed, crystalline and optical anisotropy are largely preserved as evidenced by high resolution transmission electron microscopy and angle-resolved Raman spectroscopy. Further Raman measurements identify Raman modes to determine crystalline anisotropy direction and offer insights into the degree of anisotropy. Overall results introduce Nb(1-x)TixS3 as a new and easy phase change material and mark the first phase engineering in anisotropic van der Waals (vdW) trichalcogenide systems for their potential applications in two-dimensional superconductivity, electronics, photonics, and information technologies.",
        "keywords": [
            "2D materials",
            "alloys",
            "crystal growth",
            "material synthesis",
            "quantum materials"
        ],
        "authors": [
            {
                "name": "Kedi Wu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Mark Blei",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Lei Liu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Cassondra Brayfield",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "David Wright",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Houlong Zhuang",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "ADVANCED MATERIALS",
        "year": 2020
    },
    "0VutQdzZ": {
        "id": "0VutQdzZ",
        "title": "Vascular Protection Mechanism of Integrated Traditional Chinese and Western Medicine in Treating Ischemic Stroke",
        "abstract": "Nowadays,ischemic stroke gradually become a major cause of morbidity and mortality.Furthermore,the hotspot and difficulty on neuroscience research is looking for new and effective intervention strategy.In general,vascular protection belongs to neuroprotection in spite of slight distinction in entity.In practical terms,any strategy proven to reduce the incidence of fatal and nonfatal vascular events could be said to be \"vascular protection\",including antithrombotic and antihypertensive therapies,and agents with direct beneficial effects on vascular endothelium.Moreover,considering that vascular events include myocardial infarction,stroke and claudication,so most prominent agents in this realm include the statins,angiotensin converting enzyme inhibitors(ACEI),and angiotensin receptor blockers(ARBs).In traditional Chinese medicine,some therapies,such as activating blood circulation to dissipate blood stasis,invigorating the kidney and replenishing the essence,dispelling wind and removing obstruction in the meridians as well as warming yang to promote diuresis,are possibly related to vascular protection,nevertheless,positive effect should be waiting for more evidence in the near future.",
        "keywords": [
            "Ischemic stroke",
            "Dispelling wind and removing obstruction in the meridians",
            "Warming yang to promote diuresis",
            "Invigorating the kidney and replenishing the essence",
            "Neuroprotection",
            "Activating blood circulation to dissipate blood stasis",
            "Vascular protection"
        ],
        "authors": [
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "FU Xiao-dong",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            },
            {
                "name": "WANG Wen-jian",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu Nanjing ,China"
            }
        ],
        "venue": "Journal of Anhui Traditional Chinese Medical College",
        "year": 2007
    },
    "H7spQZFV": {
        "id": "H7spQZFV",
        "title": "The effects of lysophosphatidic acid on the proliferation and collagen synthesis of cardiac fibroblasts",
        "abstract": "Objective:To investigate the effects of lysophosphatidic acid(LPA) on the proliferation and collagen synthesis of cardiac fibroblasts(CF) in vitro.Methods:Isolated and cultured neonatal Sprague-Daeley(SD) rats were used as experimental model.CF proliferation was measured by MTT assay.Collagen synthesis was measured by hydroxyproline alkaline hydrolysis assay.Results:①A_(490) value of CF by MTT assay increased with the elevation of LPA concentration.48 h later,only A_(490) value of 10~(-6) μmol/L group was significantly higher than that of control group(P<0.05).72 h later,A_(490) value of 10~(-8),10~(-7),10~(-6) μmol/L groups were significantly higher than that of control group(P<(0.05).) 96 h later,A_(490) value of 10~(-8),10~(-7),10~(-6) μmol/L groups were significantly higher than that of control group too.②The secretion of collagen increased with the elevation of LPA concentration and action time.48 h later,Only the collagen concentration of 10~(-6) μmol/L group was increased significantly compared to the control group(P<(0.01).) 72 h later,the concentration of 10~(-6),10~(-7)μmol/L groups were increased significantly compared to the control group(P<0.05,P<0.01).96 h later,the concentration of all 3 treatment groups were increased significantly compared to the control group(P<(0.05,) P<0.01),the concentration of 10~(-6)μmol/L groups was increased significantly compared to that of the 10~(-7) and 10~(-8)μmol/L groups((P<0.05)). Conclusion:LPA can increase the proliferation and collagen synthesis in rats.",
        "keywords": [
            "Cardiac fibroblasts",
            "Lysophosphatidic",
            "Proliferation",
            "Collagen synthesis"
        ],
        "authors": [
            {
                "name": "XIU Chun-ying",
                "org": "The Pre-clinical Medicine College,Nanjing University of Traditional Chinese Medicine,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "The Pre-clinical Medicine College,Nanjing University of Traditional Chinese Medicine,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "JIN Jie",
                "org": "Past-doctor's Scientific Research Work Station,Nanjing General Hospital of Nanjing Military Command,PLA, Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2006
    },
    "oRK1qlN6": {
        "id": "oRK1qlN6",
        "title": "The association of meat intake and the risk of type 2 diabetes may be modified by body weight.",
        "abstract": "To investigate the association between meat intake and incidence of type 2 diabetes (type 2 DM) in a large cohort of middle-aged women.Incident cases of type 2 DM were identified during an average of 4.6 years of follow-up in a prospective cohort study of 74,493 middle-aged, Chinese women (mean age +/- SD =51.7+/- 8.97 years). Participants completed in-person interviews that collected information on type 2 DM risk factors such as dietary factors and physical activity in adulthood. Anthropometric indices were measured. Dietary intake was assessed using a validated food frequency questionnaire (FFQ). We included in the current analysis 70,609 women who had no prior history of type 2 DM at study recruitment and who had valid dietary data. The association of type 2 DM with unprocessed meat intake (g/day) and the frequency of consumption of processed meat was evaluated using the Cox model with adjustment for age, kcals/day, body mass index (BMI), waist to hip ratio (WHR), vegetable intake, smoking, alcohol consumption, physical activity, income level, education level, occupation status, and history of hypertension and chronic disease at baseline.We identified 1972 incident cases of type 2 DM during a total of 326,581 person-years of follow up. Intake of unprocessed meat, particularly poultry, was associated with a decrease in the risk of type 2 DM in this cohort. The fully adjusted relative risks (RRs) for quintiles of total unprocessed meat intake were 1.00, 0.78, 0.83, 0.74, and 0.83 (P for trend: <0.01). When the joint effect between meat intake and BMI categories was evaluated, high intake of total unprocessed meat appeared to be associated with an increased risk of type 2 DM among obese women but a reduced risk among lean women (P value for the interaction tests = 0.05). Processed meat consumption was positively associated with the risk of type 2 DM. The adjusted RR was 1.15 (95% 1.01-1.32) in women consuming processed meats compared to those who did not consume processed meats (P=0.04).Processed meat intake was positively associated with the risk of type 2 DM. There was an indication that the effect of unprocessed meat intake on type 2 DM may be modified by BMI.",
        "keywords": [
            "middle-aged women",
            "meat intake",
            "type 2 diabetes",
            "body weight",
            "bioinformatics",
            "relative risk",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Raquel Villegas",
                "org": "Vanderbilt Epidemiology Center|Vanderbilt University Medical Center|Vanderbilt-Ingram Cancer Center"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Epidemiology Center|Vanderbilt University Medical Center|Vanderbilt-Ingram Cancer Center"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Department of Epidemiology|Shanghai Cancer Institute|Department of Medicine|Vanderbilt University|Vanderbilt Epidemiology Center"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Epidemiology Center|Vanderbilt University Medical Center|Vanderbilt-Ingram Cancer Center"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Epidemiology Center|Vanderbilt University Medical Center|Vanderbilt-Ingram Cancer Center"
            },
            {
                "name": "Honglan Li",
                "org": "Department of Epidemiology|Shanghai Cancer Institute|Department of Medicine|Vanderbilt University|Vanderbilt Epidemiology Center"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Epidemiology Center|Vanderbilt University Medical Center|Vanderbilt-Ingram Cancer Center"
            }
        ],
        "venue": "International journal of medical sciences",
        "year": 2006
    },
    "GaNWIssa": {
        "id": "GaNWIssa",
        "title": "Effect of Acupuncture on Aortal NO and NOS in High Fat Rats",
        "abstract": "Objective:To investigate the influences of high-fat dietary on fasting blood lipid and aortic nitric oxide synthase,as well as the effect of acupuncture on aortic nitric oxide synthase system in Sprague-Dawley rats fed with high fat.Methods:After the serum levels of fasting blood lipid,nitric oxide and myeloperoxidase were detected,17 male Spra-gue-Dawley rats fed with high-fat dietary for 12 weeks were devided randomly into model(8) and acupuncture(9) group according to their bodyweight.Aortic contents of nitric oxide,total nitric oxide synthase,inducible nitric oxide syn-thase and constitutive nitric oxide synthase(cNOS) were examined after treatment for 4 weeks.Results:Compared with normal-diet rats,serum levels of TG,TC and MPO raised obviously and serum NO depressed markedly in high-fat di-etary rats.Compared with the control,atortic contents of NO and cNOS decreased obviously in model group.Atortic con-tents of NO and cNOS in acupuncture group were higher markedly than model.Conclusion:High-fat dietary induces hy-perlipidemia and enhances oxidative stress states in Sprague-Dawley rats.Acupuncture has favorable regulating function on the aortic NOS system in high-fat rats.",
        "keywords": [
            "acupuncture",
            "nitric oxide",
            "high-fat",
            "nitric oxide synchase"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": "Department of TCM and Western Medicine,Nanjing General Hospital of Nanjing Military Area Command of Chinese PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2010
    },
    "SgZtdNMQ": {
        "id": "SgZtdNMQ",
        "title": "Engineering excitonic dynamics and environmental stability of post-transition metal chalcogenides by pyridine functionalization technique",
        "abstract": "Owing to their strong photon emission, low excitonic binding energies, and nearly-ideal band offset values for water splitting reactions, direct gap quasi-2D gallium chalcogenides are potential candidates for applications in energy harvesting, optoelectronics, and photonics. Unlike other 2D materials systems, chemical functionalization of gallium chalcogenides is still at its seminal stages. Here, we propose vapor phase pyridine intercalation technique to manipulate optical properties of gallium chalcogenides. After functionalization, the excitonic dynamics of quasi-2D GaSe change significantly as evidenced by an increase in integrated PL intensity and emergence of a new emission feature that is below the band edge. Based on our DFT calculations, we attribute these to formation of bound exciton complexes at the trap sites introduced by chemical reaction between pyridine and GaSe. On the contrary, pyridine functionalization does not impact the optical properties of GaTe, instead treats GaTe surface to prevent oxidization of tellurium atoms. Overall, results suggest novel ways to control properties of gallium chalcogenides on demand and unleash their full potential for a range of applications in photonics and optoelectronics. ",
        "keywords": [],
        "authors": [
            {
                "name": "xiuqing meng",
                "org": "zhejiang normal university"
            },
            {
                "name": "anupum pant",
                "org": "arizona state university"
            },
            {
                "name": "hui cai",
                "org": "arizona state university"
            },
            {
                "name": "jun kang",
                "org": "university of antwerp"
            },
            {
                "name": "hasan sahin",
                "org": "zhejiang normal university"
            },
            {
                "name": "bin chen",
                "org": "arizona state university"
            },
            {
                "name": "kedi wu",
                "org": "arizona state university"
            },
            {
                "name": "sijie yang",
                "org": "arizona state university"
            },
            {
                "name": "aslihan suslu",
                "org": "arizona state university"
            },
            {
                "name": "f m peeters",
                "org": "university of antwerp"
            },
            {
                "name": "sefaattin tongay",
                "org": "arizona state university"
            }
        ],
        "venue": "Nanoscale",
        "year": 2015
    },
    "eevJoKW4": {
        "id": "eevJoKW4",
        "title": "Abstract LB-322: Cruciferous vegetable intake after diagnosis of breast cancer and survival: a report from the shanghai breast cancer survival study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "sarah nechuta",
                "org": "vanderbilt university"
            },
            {
                "name": "wei lu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "pingping bao",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "x o shu",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Cancer Research",
        "year": 2012
    },
    "Qdws3Xq1": {
        "id": "Qdws3Xq1",
        "title": "Peroxisome proliferators activated receptor gamma and atherosclerosis:An update",
        "abstract": "Peroxisome proliferators activated receptor gamma(PPARγ) plays an important role in the pathogenesis of atherosclerosis.PPARγ influences the development of atherosclerosis in various ways,mainly by mediating inflammation,regulating the generation of vascular smooth muscle cells,and creating the foam cells.",
        "keywords": [
            "Atherosclerosis",
            "Monocytes/macrophage",
            "Peroxisome proliferators activated receptor gamma",
            "Generation of vascular smooth cells",
            "Inflammation"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2011
    },
    "6CaiuyFg": {
        "id": "6CaiuyFg",
        "title": "Expressions of myocardial α-MHC and β-MHC mRNA in rats with pressure overload",
        "abstract": "Objective: Recent years has witnessed new progress in the molecular genetic study of the relationship between the myosin heavy chain and myocardial hypertrophy.This study aimed to observe the expressions of myocardial α-myosin heavy chain(α-MHC) and β-myosin heavy chain(β-MHC) mRNA in rats with pressure overload,and to investigate the mechanism by which abdominal aorta constriction induces left ventricular hypertrophy.Methods: Male SD rats were randomly divided into a sham operation and model group.The models were made by clamping the suprarenal abdominal aorta with a silver chip.Eight weeks later,changes in the left ventricular mass index(LVMI) and the ultra microstructure of the left ventricular myocyte were observed,and the expressions of α-MHC and β-MHC in the myocardial tissue were detected by RT-PCR.Results: Compared with the sham operation group,the model rats showed markedly increased LVMI(P<0.05),decreased expression of α-MHC mRNA and elevated expression of β-MHC mRNA in the left ventricular myocardial tissue(P<0.05).Conclusion: Pressure overload increased the pathophysiologic changes of the left ventricular hypertrophy induced by abdominal aortic constriction for 8 weeks,which may be correlated with the downregulated expression of α-MHC and upregulated expression of β-MHC.",
        "keywords": [
            "Gene expression",
            "β-MHC",
            "Myocardial hypertrophy",
            "Pressure overload",
            "α-MHC"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "at2Tx42s": {
        "id": "at2Tx42s",
        "title": "Effect of Acupuncture on Fatty-insulin Axis in Type 2 Obese Diabetic",
        "abstract": "Objective:To research the relationship between leptin and insulin and the effect of acupuncture on fatty-insulin axis in type 2 obese diabetes.Methods:35 patients with type 2 obese diabetes were performed acupuncture for 3 courses.Levels of fasting blood plasma glucose(FPG),fasting insulin(FINS) and fasting leptin(FLP) were measured to calculate IAI and Homa-IR index.Results:There exist hyperglycemia,hyperinsulinemia and hyperleptinemia in type 2 obese diabetes cases before acupuncture.Levels of FBS,FINS and FLP dropped obviously after acupuncture.Conclusion:There is dysfunction of fatty-insulin axis in type 2 obese diabetes.Acupuncture can regulate the function of fatty-insulin axis in type 2 obese diabetes.",
        "keywords": [
            "Acupuncture",
            "Type 2 Obese diabetes",
            "Fatty-insulin axis"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": " Nanjing general hospital of Nanjing military command %%#Nanjing %%#"
            },
            {
                "name": "YUAN Ai-hong",
                "org": " Nanjing general hospital of Nanjing military command %%#Nanjing %%#"
            },
            {
                "name": "WEI Qun-li",
                "org": " Nanjing general hospital of Nanjing military command %%#Nanjing %%#"
            }
        ],
        "venue": "Journal of Emergency in Traditional Chinese Medicine",
        "year": 2009
    },
    "PkF0h6ER": {
        "id": "PkF0h6ER",
        "title": "Sumi Jo in Shanghai",
        "abstract": "OUTLINE/ Back in 2008 when Sumi Jo made her debut in Beijing, she had already hinted at her hopes to perform in Shanghai sometime in the future.On May 29,in a concert presented by the Shanghai Symphony Orchestra entitled\"Sumi Jo and Lynn Harrell,\"the Korean soprano not only fulfilled her promise,but made her fans deliriously happy.Her radiance tilled the Shanghai Concert Hall,despite her performing only three arias that evening.",
        "keywords": [],
        "authors": [
            {
                "name": "栀子",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "jXTq1uDv": {
        "id": "jXTq1uDv",
        "title": "Dietary carbohydrates, fiber, and breast cancer risk in Chinese",
        "abstract": "Background: Few studies have investigated the association of di- etary carbohydrate and fiber intake with breast cancer risk in women in China, where carbohydrate intake is traditionally high. Objective: The objective was to prospectively evaluate the associ- ation of dietary carbohydrates, glycemic index, glycemic load, and dietary fiber with breast cancer risk and to determine whether the effect of these dietary intakes is modified by age and selected insulin- or estrogen-related risk factors. Design: A total of 74,942 women aged 40-70 y were recruited into the Shanghai Women's Health Study, a population-based cohort study. Dietary intake was assessed by in-person interviews. A Cox pro- portional hazards regression model was used to evaluate associa- tions. Results: During an average of 7.35 y of follow-up, 616 incident breast cancer cases were documented. A higher carbohydrate intake was associated with a higher risk of premenopausal breast cancer (P for trend ¼ 0.002). Compared with the lowest quintile, the hazard ratios (and 95% CIs) were 1.47 (1.00, 2.32) and 2.01 (1.26, 3.19) for the fourth and fifth quintiles, respectively. A similar pattern was found for glycemic load. The association between carbohydrate intake and breast cancer was significantly modified by age; the increased breast cancer risk associated with carbohydrate intake was restricted to women who were younger than 50 y. No significant association of breast cancer risk with glycemic index or dietary fiber intake was found. Conclusion: Our data suggest that a high carbohydrate intake and a diet with a high glycemic load may be associated with breast cancer risk in premenopausal women or women ,50 y. Am J Clin Nutr 2009;89:283-9.",
        "keywords": [],
        "authors": [
            {
                "name": "Wanqing Wen",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            },
            {
                "name": "Honglan Li",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Bu-Tian Ji",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "0xZwbblS": {
        "id": "0xZwbblS",
        "title": "Epstein–Barr Virus Antibody Titers Are Not Associated with Gastric Cancer Risk in East Asia",
        "abstract": "Epstein–Barr virus (EBV)-positive gastric cancers represent a distinct subtype of gastric cancers and account for nearly 10% of the gastric cancer burden, yet risk detection strategies for this cancer subtype are lacking.",
        "keywords": [
            "Epstein–Barr virus",
            "Gastric cancer",
            "Multiplex serology"
        ],
        "authors": [
            {
                "name": "Matthew G. Varga",
                "org": "Department of Epidemiology, Gillings School of Global Public Health and Lineberger Comprehensive Cancer Center,University of North Carolina at Chapel Hill,Chapel Hill,USA"
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Ingram Cancer Center,Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "Tim Waterboer",
                "org": "Division of Molecular Diagnostics of Oncogenic Infections, Research Program in Infection, Inflammation, and Cancer,German Cancer Research Center (DFKZ),Heidelberg,Germany"
            },
            {
                "name": "Gwen Murphy",
                "org": "Division of Cancer Epidemiology and Genetics,National Cancer Institute,Bethesda,USA"
            },
            {
                "name": "Taichi Shimazu",
                "org": "Epidemiology and Prevention Group,National Cancer Center,Tokyo,Japan"
            },
            {
                "name": "Phil R. Taylor",
                "org": "Division of Cancer Epidemiology and Genetics,National Cancer Institute,Bethesda,USA"
            },
            {
                "name": "You-Lin Qiao",
                "org": "Department of Cancer Epidemiology,Chinese Academy of Medical Sciences and Peking Union Medial College,Beijing,China"
            },
            {
                "name": "Sue K. Park",
                "org": "Department of Biomedical Sciences, Cancer Research Institute,Seoul National University College of Medicine,Seoul,Korea"
            },
            {
                "name": "Keun-Young Yoo",
                "org": "Department of Preventive Medicine,Seoul National University College of Medicine,Seoul,Korea"
            },
            {
                "name": "Sun Ha Jee",
                "org": "Department of Epidemiology and Health Promotion, Institute for Health Promotion,Yonsei University,Seoul,Korea"
            },
            {
                "name": "Eo Rin Cho",
                "org": "Department of Epidemiology and Health Promotion, Institute for Health Promotion,Yonsei University,Seoul,Korea"
            },
            {
                "name": "Jeongseon Kim",
                "org": "Division of Cancer Epidemiology and Prevention, Research Institute,National Cancer Center,Goyang,Korea"
            },
            {
                "name": "Christian C. Abnet",
                "org": "Division of Cancer Epidemiology and Genetics,National Cancer Institute,Bethesda,USA"
            },
            {
                "name": "Shoichiro Tsugane",
                "org": "Epidemiology and Prevention Group,National Cancer Center,Tokyo,Japan"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Ingram Cancer Center,Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Ingram Cancer Center,Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "Michael Pawlita",
                "org": "Division of Molecular Diagnostics of Oncogenic Infections, Research Program in Infection, Inflammation, and Cancer,German Cancer Research Center (DFKZ),Heidelberg,Germany"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Ingram Cancer Center,Vanderbilt University Medical Center,Nashville,USA"
            },
            {
                "name": "Meira Epplein",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Ingram Cancer Center,Vanderbilt University Medical Center,Nashville,USA"
            }
        ],
        "venue": "Digestive Diseases and Sciences",
        "year": 2018
    },
    "U922yjCT": {
        "id": "U922yjCT",
        "title": "Correlations of lateral position and posyertoanterior lumbar bone mineral density in female",
        "abstract": "Objective To analyze the dependability of lateral position and P-A position lumbar bone mineral density(BMD) in female and to explore variation regularity of female′s lumbar vertebra BMD.Methods 166(45 yr～70 yr) healthy females were selected,whose P-A position BMD(L2-4BMD) and lateral position BMD(B2-4BMD)were measured by GE Lunar Prodigy dual energy X-ray absorptiometry.Observed objects were divided into 4 groups,pre-menopausal group with normal L2-4BMD,postmenopausal group with abnormal L2-4BMD,post-menopausal group with normal L2-4BMD and post-menopausal group with abnormal L2-4BMD,to analyze the correlations of L2-4BMD,B2-4BMD,years of age and body mass index.Regression equation was then established.Results In the L2-4BMD normal groups,there was significant deviation between pre-menopausal group and post-menopause group and BMD in the post-menopause group decreased rapidly.In the L2-4BMD abnormal groups,significant deviation between pre-menopausal group and post-menopausal group was observed.Compared with L2-4 BMD pre-menopausal group,L2-4BMD in post-menopausal group was significantly decreased while B2-4BMD was not.There were clear-cut correlations between B2-4BMD and L2-4BMD in each group.B2-4BMD in post-menopausal group with normal L2-4 BMD was correlated significantly with years of menopause.Multiple regression analysis showed that dependent variable B2-4BMD(y) was mainly determined by L2-4 BMD(X1),years of menopause(X2) and BMI(X3).Regression equation of each of the 4 groups was: y=0.147+ 0.501 X1-0.007 X2,y=-0.437+0.457 X1+0.024 X3,y=0.102+0.559 X1,y=-0.350+0.947 X1.Conclusion Clear-cut correlations exist between B2-4BMD and L2-4BMD in female.B2-4BMD in female is related to L2-4BMD.Females of post-menopause should check BMD as soon as they can.",
        "keywords": [
            "osteoporosis",
            "female",
            "bone mineral density"
        ],
        "authors": [
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "JIN Jie",
                "org": "Postdoctoral Workstation Nanjing Military Hospital,Jiangsu,Nanjing "
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            }
        ],
        "venue": "Journal of Clinical Medicine in Practice",
        "year": 2009
    },
    "Qe6al7q9": {
        "id": "Qe6al7q9",
        "title": "Effects of methotrexate on the secretion of interferon-γ and interleukin-4 by rheumatoid arthritis′ circum-citrullinated peptide antigen specific T cell",
        "abstract": "Objective:To observe the effects of methotrexate(MTX) on the secretion of interferon-γ(IFN-γ) and interleukin-4(IL-4) by rheumatoid arthritis′ circum-citrullinated peptide antigen specific T cells(CCP/AST).Methods:The rheumatoid arthritis′ blood peripheral lymphocytes(PBLs) were cultured in vitro for 72 h,and divided into three groups:lymphocytes only(RA blank group),lymphocytes with CCP at the final concentration of 20 μg/ml(RA CCP group),lymphocytes with CCP and MTX both at the final concentration of 20 μg/ml(RA MTX group).PBLs from health volunteers were cultured in vitro(abbreviated blank control group).The concentrations of IFN-γ and IL-4 were measured by ELISA.Results:Compared with RA CCP group:IFN-γ level of PBLs was lower and IL-4 was higher in RA MTX group,IFN-γ/IL-4 ratio was down-regulated(P<0.05-P<0.01),which had the statistical significances.Conclusions:MTX can regulate the levels of IFN-γ and IL-4 in rheumatoid arthritis′ CCP/AST(P<0.05).MTX can inhibit CCP induced TH1 cytokine,and up-regulate TH2 cytokine expression.The regulation of rheumatoid arthritis′ CCP/AST by MTX may be one of the effective pathway in treating arthritis rheumatoid.",
        "keywords": [
            "interleukin-4",
            "antigen specific T cell",
            "rheumatoid arthritis",
            "methotrexate",
            "interferon-γ",
            "circum-citrullinated peptide"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing Jiangsu ,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing Jiangsu ,China"
            }
        ],
        "venue": "Journal of Bengbu Medical College",
        "year": 2011
    },
    "Ds4i2JzV": {
        "id": "Ds4i2JzV",
        "title": "Plasma selenoprotein P concentration and lung cancer risk: Results from a case-control study nested within the Shanghai Men's Health Study.",
        "abstract": "Selenoprotein P (SELENOP) is a major selenoenzyme in plasma and linked to antioxidant properties and possibly to lung cancer; however, supporting evidence is limited. We investigated the association between pre-diagnostic plasma SELENOP concentration and lung cancer risk in a case-control study of 403 cases and 403 individually matched controls nested within the Shanghai Men's Health Study. SELENOP concentration in pre-diagnostic plasma samples was measured by a sandwich enzyme-linked immunosorbent assay. Cases were diagnosed with lung cancer between 2003 and 2010. Multivariate conditional logistic regression was used to estimate odds ratios (OR) and the corresponding 95% confidence intervals (CI) for studying the association between plasma SELENOP concentration and lung cancer risk. Cases had slightly lower plasma SELENOP concentration than controls (4.3 +/- 1.2 versus 4.4 +/- 1.1 mg/l, P difference = 0.09). However, the multivariate analysis showed no association between plasma SELENOP concentration and lung cancer risk among all participants (OR = 1.08, 95% CI = 0.54-2.14 for quartile 4 versus quartile 1), or by smoking status or tumor aggressiveness. In contrast, although the number of cases was limited, plasma SELENOP concentration was positively associated with lung adenocarcinoma risk (OR = 5.38, 95% CI = 1.89-15.35 for tertile 3 versus tertile 1), but not with squamous cell lung carcinoma (OR = 1.69, 95% CI = 0.43-6.70). Our study of adult men living in selenium non-deficient areas in China provides little support for the inverse association between pre-diagnostic plasma SELENOP concentration and lung cancer risk. Our finding of a positive association with risk of lung adenocarcinoma needs to be interpreted with caution.",
        "keywords": "",
        "authors": [
            {
                "name": "Yumie Takata",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Raymond F Burk",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Gastroenterol Hepatol & Nutr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Kristina E Hill",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Div Gastroenterol Hepatol & Nutr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Jing Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Epidemiol Ctr, 221 Kirkland Hall, Nashville, TN 37235 USA"
            }
        ],
        "venue": "CARCINOGENESIS",
        "year": 2018
    },
    "IiisvUNk": {
        "id": "IiisvUNk",
        "title": "Abstract A92: Oxidative stress, obesity, and breast cancer risk: results from the Shanghai women health study (SWHS).",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "n rothman",
                "org": ""
            },
            {
                "name": "wanqing wen",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": ""
            },
            {
                "name": "ginger l milne",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "x o shu",
                "org": ""
            },
            {
                "name": "y t gao",
                "org": ""
            },
            {
                "name": "qi dai",
                "org": ""
            },
            {
                "name": "w h chow",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": ""
            }
        ],
        "venue": "Cancer Prevention Research",
        "year": 2008
    },
    "EB3Nyas6": {
        "id": "EB3Nyas6",
        "title": "Effect of fasudil on angiotensin converting enzyme 2 and angiotensin(1-7) in rat myocardium",
        "abstract": "Objective To study the effect of fasudil on angiotensin converting enzyme 2(ACE2) and angiotensin(1-7) in rat myocardium.Methods An overload pressure model of SD rats was established by constricting abdominal aorta.Four weeks after operation,the rats were divided into sham operation group(n=8),model group(n=10),high fasudil dose group(n=9),and low fasudildose group(n=9).At the 8 weekend after operation,left ventricle mass index(LVMI) was calculated,myocardial hydroxyproline(HYP) level in myocardial tissues stained with HE and Masson collagen was measured by alkaline hydrolysis.ACE and ACE2 protein levels were measured by immunohistochemical analysis.Expression of ACE2 mRNA was detected by RT-PCR and Western blot,respectively.Angiotensin Ⅱ and angiotensin(1-7) levels were measured by ELISA.Results The LVMI and the levels of HYP,collagen deposition in myocardial interstitium,ACE,angiotensin Ⅱwere significantly higher whereas the levels of ACE2,ACE2 mRNA and angiotensin(1-7) were significantly lower in model group than in sham operation group(P<0.01).The LVMI and the levels of HYP,collagen deposition in myocardial interstitium,ACE and angiotensin Ⅱ were significantly lower whereas the levels of ACE2 protein,ACE2 mRNA and angiotensin(1-7) were significantly higher in high and low fasudil dose groups than in model group(P<0.05,P<0.01).Conclusion Fasudil inhibits overload pressure-induced myocardial fibrosis by improving ACE2 and angiotensin(1-7).",
        "keywords": [
            "fasudil",
            "Rho-associated kinases",
            "cytoskeleton",
            "peptidyl-dipeptidase A",
            "angiotensins"
        ],
        "authors": [
            {
                "name": "ZHANG Pei-yong",
                "org": "Nanjing School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Nanjing School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Chinese Journal of Geriatric Heart Brain and Vessel Diseases",
        "year": 2013
    },
    "Af0s7ZLd": {
        "id": "Af0s7ZLd",
        "title": "Theory and application of connectivity mask-based reconstruction opening operator",
        "abstract": "A new reconstruction operator based on second-generation connectivity mask was proposed to efficiently utilize the multi-channel information and improve the filtering performance of reconstruction operator. The connectivity mask image, reconstruction mask image and reconstruction marker image are firstly obtained based on different channel information and constrictions. According to the mask-based second-generation connectivity, the proposed operator relabels the connected components in the reconstruction mask image. By partition and clustering, a new connectivity space is formed from the reconstruction mask image. In the new connectivity space, some connected components are selectively reconstructed according to the corresponding regions in the marker image. By flexibly selecting the connectivity mask and the mark image, and effectively utilizing the grads information, color information and multi-channel information, the mask-based reconstruction operator can solve the problem of information restriction of the traditional reconstruction operator.",
        "keywords": [
            "Image segmentation",
            "Morphological filter",
            "Reconstruction operator",
            "Second-generation connectivity"
        ],
        "authors": [
            {
                "name": "CAI Jin-hui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHANG Guang-xin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "HOU Di-bo",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Zhejiang Daxue Xuebao(Gongxue Ban)/Journal of Zhejiang University (Engineering Science)",
        "year": 2010
    },
    "NaN1v0aZ": {
        "id": "NaN1v0aZ",
        "title": "Reassessment of the efficacy of risedronate sodium capsules in the treatment of postmenopausal osteoporosis",
        "abstract": "Objective To evaluate efficacy of risedronate sodium capsules in the treatment of postmenopausal osteoporosis(PMOP) by the least significant change(LSC)-adjusted method(LAM).Methods This is a randomized double-blind,placebo-controlled clinical trial.42 patients with PMOP were randomly divided into 2 groups: trial group(n=21) and control group(n=21).During 12 months,patients in the trail group received risedronate sodium capsules orally every morning,while patients of control group took placebo orally every morning,and meanwhile all patients took calcichew D orally every night.The double-energy bone density measurement was used to determine lumbar and hip bone mineral density(BMD) at 3 time points(before treatment,6 months and 12 months after treatment).Meanwhile,the effect on BMD was evaluated by LAM to compare with the result evaluated by normal distribution analytical method(NAM).Results The sample change data for lumbar BMD by(LAM) showed that there was statistical significance in the changes 6 and 12 months after continuous treatment between the trial group and control group respectively(P<0.05),while no statistical significance in the change data for hip BMD was observed between the two groups(P>0.05).The results of efficacy about BMD by LAM were consistent with those by NAM.Conclusion The results by LAM and NAM have high concordance.There are both advantages and disadvantages respectively in the evaluation of the efficacy about BMD by LAM and NAM.The two methods should be used alone or meanwhile when necessary.",
        "keywords": [
            "least significant change",
            "dual-energy X-ray absorptiometry",
            "postmenopausal osteoporosis",
            "bone mineral density"
        ],
        "authors": [
            {
                "name": "GUO Junhao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "YAO Rubing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhiming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Acta Academiae Medicinae Xuzhou",
        "year": 2010
    },
    "mcRuv1GX": {
        "id": "mcRuv1GX",
        "title": "Abstract 627: Physical activity and inflammatory and oxidative status markers in Chinese women",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "shenghui wu",
                "org": "vanderbilt university"
            },
            {
                "name": "x o shu",
                "org": "vanderbilt university"
            },
            {
                "name": "wongho chow",
                "org": "national cancer institute"
            },
            {
                "name": "yongbing xiang",
                "org": ""
            },
            {
                "name": "xianglan zhang",
                "org": "vanderbilt university"
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "qiuyin cai",
                "org": "vanderbilt university"
            },
            {
                "name": "ginger l milne",
                "org": "vanderbilt university"
            },
            {
                "name": "butian ji",
                "org": "national cancer institute"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "nathaniel rothman",
                "org": "national cancer institute"
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "g yang",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Cancer Research",
        "year": 2012
    },
    "G0GTE29T": {
        "id": "G0GTE29T",
        "title": "Sources of variation in nutrient intakes among men in Shanghai, China.",
        "abstract": "Random errors, from any source, will attenuate epidemiological risk estimates. Before we launched the Shanghai Men's Health Study (SMHS), a large population-based cohort study investigating the diet-cancer association among Chinese men, a dietary calibration study was conducted among 96 men aged 40-75 years (mean age 56.5 years), with biweekly 24-hour dietary recalls (24HDRs) implemented over a 1-year period. Data from this study were analysed to evaluate the nature and magnitude of variances for intake of 26 nutrients among SMHS participants, to compare variance ratios of 26 nutrients among Chinese men and women and individuals in other studies, and to estimate the number of 24HDRs required for future dietary calibration studies in similar populations.Ninety-six healthy, free-living men in Shanghai were administered biweekly 24HDR interviews 24 times over a 1-year period. To assess between-individual and within-individual contributions to variance, a mixed effects model was fitted and ratios of within-individual to between-individual (sigma(w)(2)/sigma(b)(2)) dietary intake variances were computed.Shanghai, China.In agreement with reports from studies conducted in the USA and many other countries, we found that within-individual variances were usually larger than between-individual variances in dietary intake for all nutrients. The sum of all other variation (e.g. weekday and weekend, seasonal, interviewer) accounted for less than 5% of total variation. Ratios of within- to between-individual variances (for log-transformed data) ranged from 1.25 for carbohydrate intake to near 8 for delta-tocopherol intake.The results of this study suggest that among middle-aged and elderly Chinese men in Shanghai, within- and between-individual variation account for more than 95% of the total variation for 26 nutrients. Further dietary validation studies in the same population could be adequately carried out with only 12 days of dietary recalls, if 100 participants were enrolled.",
        "keywords": [
            "component of variance",
            "within-individual variation",
            "china",
            "between-individual variation",
            "24-hour dietary recall",
            "nutrients",
            "public health"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Gong Yang",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "James R Hebert",
                "org": ""
            },
            {
                "name": "Da-Ke Liu",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            }
        ],
        "venue": "Public health nutrition",
        "year": 2005
    },
    "Cib1gxph": {
        "id": "Cib1gxph",
        "title": "Effects of total flavonoids of epimedium on aorta vascular endothelial function in hyperlipidemic rats",
        "abstract": "AIM: To explore total flavonoids of epimedium(TFE) on nitric oxide(NO) and nitric oxide synthetase(NOS) in aorta in hyperlipidemic rats and to explore the possible mechanism of anti-atherosclerosis(AS).METHODS: According to body weight,35 male Sprague Dawley(SD) rats were randomly divided into the full diet group(n=9) and the high-fat(HF) diet group(n=26) that was fed a HF diet for 12 weeks.Serum lipid levels were then measured.An ideal experimental rat model of hyperlipidemia was made when lipid level was higher in the HF diet group.According to body weight,26 male SD rats were then randomly divided into three groups,namely,model group,low-dose [100 mg/(kg·rat)] TFE group and high-dose [200 mg/(kg·rat)] TFE group.After 16 weeks of feeding,serum lipid(TG,TC,LDL-C,HDL-C) level was measured.Triglycerides(TG) were measured by CHOD-PAP method,total cholesterol(TC) was detected by CHOD-PAP,and low-density lipoprotein cholesterol(LDL-C) and high-density lipoprotein cholesterol(HDL-C) were measured by selectivity precipitation method.NO was determined by nitric acid reductase method,and iNOS and tNOS were determined by catalytic method(cNOS activity was obtained by subtracting iNOS activity from the total NOS activity).RESULTS: After 12 weeks of feeding,compared with those in the full diet group,the levels of TG,TG,and LDL-C in HF diet group significantly increased(P<0.01).After a 4-week treatment,compared with the model group,levels of TC and TG in TFE group were obviously lower(P<0.05 or P<0.01).The model group showed lower NO and cNOS concentrations(P<0.05 or P<0.01).The level of NO and cNOS of in the TFE group increased significantly(P<0.05,P<0.01).CONCLUSION: TFE reduces blood lipid levels and elevates NO and cNOS levels of vascular aorta in hyperlipidemic rats.",
        "keywords": [
            "epimedium",
            "nitric oxide",
            "hyperlipidemia",
            "total flavonoids",
            "nitric oxide synthetase"
        ],
        "authors": [
            {
                "name": "XU Yu-shun",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Southern Medical University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Southern Medical University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital,Nanjing Military Area Command,Southern Medical University,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Heart Journal",
        "year": 2011
    },
    "Xr1IUvid": {
        "id": "Xr1IUvid",
        "title": "Effect of curcumin on rats with adjuvant arthritis fibroblast-like synovial cell proliferation",
        "abstract": "Objective:To observe the effect of curcumin on rats with adjuvant arthritis fibroblast-like synovial cells(FLS) cell proliferation,cell cycle and the impact of cyclin D1.Methods:Primary culture of rat adjuvant arthritis FLS.Passage 3 were added to the concentration of FLS 10,20,40,80 μmol/L of curcumin solution,incubated 24 h,72 h.MTT assay of drugs on FLS proliferation,cell cycle analysis by flow cytometry,respectively,and cyclin D1.Results:After 24 h,40,80 μmol/L concentrations of MTT optical density compared with the control group,the difference was statistically significant(P<0.05),80 μmol/L concentrations and the proportion of G1 phase cells Cyclin D1 fluorescence index of the control group also had a significant difference(P<0.05);were cultured 72 h,10,20,40,80 μmol/L of various concentrations of curcumin group of optical density,G1 phase cell percentage and the proportion of cyclin D1 compared with the control group,the difference was statistically significant(P<0.05).Conclusion:Curcumin can inhibit adjuvant arthritis in rats fiber-like synovial cell proliferation,cell arrest at G1 phase,may reduce the role of cyclin D1 expression.",
        "keywords": [
            "protein cycle D1",
            "rheumatoid arthritis",
            "cell cycle",
            "fibroblast-like synovial cells",
            "curcumin"
        ],
        "authors": [
            {
                "name": "Shang Wei",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Zhao Zhiming",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Zheng Zhaoling",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Guo Junhao",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing "
            },
            {
                "name": "Cai hui",
                "org": "Nanjing General Hospital of Nanjing Military Region,Nanjing "
            }
        ],
        "venue": "Guiding Journal of Traditional Chinese Medicine and Pharmacy",
        "year": 2010
    },
    "NYuqdXRM": {
        "id": "NYuqdXRM",
        "title": "Co-transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells reduces glial scars after spinal cord injury",
        "abstract": "BACKGROUND: Previous studies have demonstrated that transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells can effectively promote the motor function and sensory function recovery of rhesus monkeys with spinal cord injury.OBJECTIVE: To validate whether co-transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells exhibits better protective effects on spinal cord glial scar of rhesus monkeys with spinal cord injury than cell transplantation alone.METHODS: Twelve rhesus monkeys were collected to prepare animal models of acute severe spinal cord injury using modified Allen's method, and then randomly divided into three groups: experimental group, co-transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells; control group, simple transplantation of bone marrow mesenchymal stem cells-derived neuron-like cells;blank control group, PBS. After 5 months, paraffin specimens of the spinal cord were made for detection of morphological and compositional characteristics of glial scar, regeneration of nerve fibers in the scar, glial scar area, and average absorbance of glial fibrillary acidic protein.RESULTS AND CONCLUSION: Glial scar in the injured spinal cord was composed of astrocytes and histocytes. Less spinal cord glial scar area and lower absorbance value could be observed in the experimental and control groups as compared with the blank control group(P < 0.05). In addition, in the blank control group, neurofilament negative fibers could be observed in the glial scar, and astrocytes proliferated obviously. The experimental and control groups showed less fibers passed through the scar area. The glial scar area and average absorbance in the experimental group was lower than that in the control group(P < 0.05). These findings suggest that compared with simple transplantation of bone marrow mesenchymal stem cells-derived neuron-like cells, co-transplantation of controlled release glial cell line-derived neurotrophic factor and bone marrow mesenchymal stem cells-derived neuron-like cells shows better protective effects spinal tissue structure after spinal cord injury, which may be one of mechanisms by which the number of glial scars is reduced to a greater extent.",
        "keywords": [
            "cell transplantation",
            "glial cell line-derived neurotrophic factor",
            "spinal cord injuries",
            "brain-derived neurotrophic factor"
        ],
        "authors": [
            {
                "name": "Liu Xiao-gang",
                "org": ""
            },
            {
                "name": "Deng Yu-bin",
                "org": ""
            },
            {
                "name": "Cai Hui",
                "org": ""
            },
            {
                "name": "Zhang Xin-peng",
                "org": ""
            },
            {
                "name": "Ma Yu-lin",
                "org": ""
            },
            {
                "name": "Wei Ke-xin",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Tissue Engineering Research",
        "year": 2013
    },
    "7vyVTrHO": {
        "id": "7vyVTrHO",
        "title": "Serum proteomic analysis of the anti‑arthritic effects of sinomenine on rats with collagen‑induced arthritis.",
        "abstract": "Rheumatoid arthritis (RA) is an autoimmune disease, which is characterized by inflammatory synovitis, and the subsequent destruction of articular cartilage and bone. Sinomenine is a traditional Chinese medicine, which has been employed as a clinical treatment for RA for several years in China. The present study investigated the anti-arthritic effects of sinomenine on Sprague-Dawley rats with collagen-induced arthritis (CIA). The differentially expressed proteins in serum were measured by proteomic analysis in order to generate a differentially expressed protein network. A total of 320 differentially expressed proteins were detected in the drug-treated group compared with in the control group. In the sinomenine-treated group, 79 differentially expressed proteins were detected compared with in the model group, and among these, 46 proteins were upregulated. Gene ontology analysis revealed that five functions were affected by sinomenine treatment of CIA rats compared with in the model group. In addition, Ingenuity (R) Pathway Analysis was used to measure enriched signaling pathways, which revealed nuclear factor-KB, histones, heat shock proteins and protein kinase B as core proteins, generating similar to 60 pair associations in the network. To the best of our knowledge, the present study is the first to perform proteomic analysis in sinomenine-treated CIA rats, and the results revealed that numerous targets were involved in the process. In addition, the present study provided a novel approach and evidence for exploring the biological effects of sinomenine. Therefore, the findings of the present study may provide a novel insight into the anti-RA mechanisms of sinomenine, and may justify further exploration into its function in other relevant diseases.",
        "keywords": [
            "sinomenine",
            "rheumatoid arthritis",
            "collagen-induced arthritis",
            "proteome"
        ],
        "authors": [
            {
                "name": "Xin Qian",
                "org": "Nanjing Univ Tradit Chinese Med, Dept Nursing, Nanjing 210023, Jiangsu, Peoples R China"
            },
            {
                "name": "Zhiming Zhao",
                "org": "Nanjing Gen Hosp, Integrated Tradit Chinese & Western Med, 305 Zhongshandong Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shang",
                "org": "Nanjing Gen Hosp, Integrated Tradit Chinese & Western Med, 305 Zhongshandong Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Zhihan Xu",
                "org": "Nanjing Univ Tradit Chinese Med, Dept Nursing, Nanjing 210023, Jiangsu, Peoples R China"
            },
            {
                "name": "Beibei Zhang",
                "org": "Nanjing Gen Hosp, Integrated Tradit Chinese & Western Med, 305 Zhongshandong Rd, Nanjing 210002, Jiangsu, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Nanjing Gen Hosp, Integrated Tradit Chinese & Western Med, 305 Zhongshandong Rd, Nanjing 210002, Jiangsu, Peoples R China"
            }
        ],
        "venue": "MOLECULAR MEDICINE REPORTS",
        "year": 2018
    },
    "HSGYylKu": {
        "id": "HSGYylKu",
        "title": "Effects of pioglitazone on the expression of AdipoR mRNA of aorta in hyperlipidemia rats",
        "abstract": "Objective To observe the effect of pioglitazone on expression of adiponectin receptor(AdipoR) of the aorta in hyperlipidemia rats.Methods SD rats were randomly devided into the high-fat diet group(HF) and normal control group(NC).HF group were fed a high-fat diet for 12 weeks,then the level of serum lipid was measured.SD rats in HF group were randomly devided into two groups: hyperlipidemia group(HL)and pioglitazone treatment group(Pio).Serum lipid level was measured in the rats and the aorta was taken for pathologic analysis.Adiponectin(APN) in serum was measured by ELISA.Real time fluorescent quantitation PCR was used to evaluate AdipoR1/2 mRNA expressions of the aorta.Results After 12 weeks' feeding,as compared with NC group,rats fed high-fat diet showed significantly higher levels of triglyceride(TG),total cholesterol(TC) and low density lipoprotein cholesterol(LDL-C)(P<0.01).After four weeks' treatment,as compared with HL group,the level of TC and TG in Pio group was obviously lower(P<0.01),and the serum APN in Pio group was obviously increased(P<0.05).Treatment with pioglitazone enhanced the mRNA expression of both AdipoR1 and AdipoR2(P<0.05 or P<0.01).Conclusions Decreased expression of AdipoR may involve in vascular impairment in rats with high-fat diet induced hyperlipidemia.Pioglitazone may exerte a significant vascular protective effect in hyperlipidemia rats,which may relate to increased serum APN and expression of AdipoR in vascular wall and contribute to their anti-atherosclerosis effect.",
        "keywords": [
            "Rat",
            "Adiponectin receptor",
            "Pioglitazone",
            "Aorta",
            "Hyperlipidemia",
            "Adiponectin"
        ],
        "authors": [
            {
                "name": "XU Yu-shun",
                "org": ".Southern Medical University/Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": ".Southern Medical University/Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            },
            {
                "name": "CAI Hui",
                "org": ".Southern Medical University/Nanjing General Hospital of Nanjing Military Command,Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Diabetes",
        "year": 2012
    },
    "p9KT0h5c": {
        "id": "p9KT0h5c",
        "title": "The central theme of The Ring:love",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "刘雪枫",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "rFPDoxHo": {
        "id": "rFPDoxHo",
        "title": "Sleep duration and its correlates in middle-aged and elderly Chinese women: the Shanghai Women's Health Study.",
        "abstract": "Abnormal sleep duration, either long or short, is associated with disease risk and mortality. Little information is available on sleep duration and its correlates among Chinese women.Using information collected from 68,832 women who participated in the Shanghai Women's Health Study (SWHS), we evaluated sleep duration and its correlations with sociodemographic and lifestyle factors, health status, and anthropometric measurements and their indexes using polynomial logistic regression.The mean age of the study population was 59.6 years (SD=9.0; range: 44.6-79.9 years) at time of sleep duration assessment. Approximately 80% of women reported sleeping 6-8 h/day, 11.5% slept 5h or less, and 8.7% slept 9h or more. As expected, age was the strongest predictor for sleep duration and was negatively correlated with sleep duration. In general, sleep duration was positively associated with energy intake, intakes of total meat and fruits, body mass index (BMI), waist-hip ratio (WHR), and waist circumference (WC) after adjustment for age and other factors. Both short and long sleep duration were negatively associated with education level, family income, and leisure-time physical activity and positively associated with number of live births, history of night shift work, and certain chronic diseases, compared to sleep duration around 7 h/day (6.5-7.4h/day). Short sleep duration was related to tea consumption and passive smoking. Long sleep duration was related to menopausal status and marital status.In this large, population-based study, we found that sleep duration among middle-aged and elderly Chinese women was associated with several sociodemographic and lifestyle factors and with disease status. The main limitation of the study is the cross-sectional design that does not allow us to draw any causal inference. However, this study provides information for future investigation into the nature of these associations so that recommendations can be developed to reduce sleep problems in middle-aged and elderly Chinese women. It also provides important information on potential confounders for investigation of sleep duration on health outcomes in this population.",
        "keywords": [
            "bmi",
            "sleep duration",
            "health status",
            "correlation",
            "socio-economic factor",
            "lifestyle",
            "chinese",
            "china",
            "sleep",
            "waist hip ratio"
        ],
        "authors": [
            {
                "name": "Xiangdong Tu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Xiaoyan Wu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "National Cancer Institute(National Cancer Institute,NIH),Bethesda,United States"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiaotong University(Shanghai Jiaotong University,Shanghai Jiao Tong University,Shanghai Jiaotong Univ.),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "Sleep medicine",
        "year": 2012
    },
    "eenxMrXt": {
        "id": "eenxMrXt",
        "title": "Application of flexible alternating-current transmission system in Jiangsu power grid",
        "abstract": "In this paper, current application and its development of flexible alternating current transmission system (FACTS) are briefly described. Targeting to solve the potential threatens in developing Jiangsu grid, feasibility for application of FACTS to improve system reliability and transfer capacity is investigated. Middle across-Yangtze-river transmission channel, southern-Suzhou system and western-Nanjing inter-city circle grid are set as the examples. The conclusions can be obtained that: with the application of FACTS, power flows in the system can be effectively controlled. The transfer capacity can be obviously improved, and induced voltage unstable problem during the severe faults such as bipolar latched in the ultra-high-voltage direct current (UHVDC) system can be prevented. Application of FACTS can also avoid the huge investment and difficult construction for the new across-river transmission channels and across-city cables. In summary, application of FACTS can prominently improve the efficiency and reliability of the system operation, and better economic and social benefits for the grid can be achieved.",
        "keywords": "",
        "authors": [
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Wanchun Qi",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Junhui Huang",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "State Grid Jiangsu Economic Research Institute, Nanjing, P.R. China"
            },
            {
                "name": "Siqi Bu",
                "org": "Department of Electrical Engineering, The Hongkong Polytechnic University, Hongkong"
            },
            {
                "name": "Tianran Yin",
                "org": "Department of Electrical Engineering, Southeast University, Nanjing, P.R. China"
            },
            {
                "name": "Xi Wu",
                "org": "Department of Electrical Engineering, Southeast University, Nanjing, P.R. China"
            }
        ],
        "venue": "electrical power and energy conference",
        "year": 2017
    },
    "9YDdCS3W": {
        "id": "9YDdCS3W",
        "title": "Establishment of pneumonia model for pneumocystis carinii and observation of its′ ultra-structure in rat",
        "abstract": "Objective To observe the pathological change of lung tissue and the ultra-structure of p.carinii,P.carinii pneumonia was induced in SD rats using Dexamethasone.Methods The P.carinii was detected by microscope with staining of Giemsa for trophozoites,GMS for cyst and HE staining for lung tissue slice.The ultra-structure of P.carinii was observed by transmission electron microscopy.Results A few trophozoites and cysts were found in the alveolar cavity at weeks 6 and more organisms in severe case at weeks 9.It were noted that the shrinken alveolar space,proliferated alveolar epithelium,broadening alveolar septum,numbers of infiltrating inflammatory cell and rosiness foam-like extravasate in the lung tissue of PCP.Many ultra-structures were observed by TEM,such as mitochondria,endoplasmic reticulum,tubular bodies,intracystic bodies,high-density specific granule,and so on.Conclusion The adherency and excessive multiplication of P.carinii,with numbers of infiltrating inflammatory cell and rosiness foam-like extravasate,play a role in the development of inreversible lung lesion in PCP rats.",
        "keywords": [
            "models",
            "pneumocystis carinii",
            "ultra-structure",
            "rats",
            "pneumonia",
            "animal"
        ],
        "authors": [
            {
                "name": "Zheng Yuqiang",
                "org": "Laboratory Medicine,Children′s Hospital of Chongqing Medical University/Ministry of Education Key Laboratory of Child Development and Disorders/Key Laboratory of Pediatrics in Chongqing/Chongqing International Science and Technology Cooperation Center for Child Development and Disorders,Chongqing ,China"
            },
            {
                "name": "Cai Hui",
                "org": "Department of Pathogen Biology,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "Wu Weihua",
                "org": "Department of Pathogen Biology,Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "Ye Bin",
                "org": "Department of Pathogen Biology,Chongqing Medical University,Chongqing ,China"
            }
        ],
        "venue": "Chongqing Medicine",
        "year": 2012
    },
    "FY4jQDAS": {
        "id": "FY4jQDAS",
        "title": "Opera Crossword Puaales",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2011
    },
    "xigwlQ3t": {
        "id": "xigwlQ3t",
        "title": "Abstract 2596: Correlation of TGF beta receptor II and pSmad2 expression with clinico-pathological factors in human breast cancer: An immunohistochemical observation from the Shanghai Breast Cancer Study",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qingchao qiu",
                "org": "vanderbilt university"
            },
            {
                "name": "yinghao su",
                "org": "vanderbilt university"
            },
            {
                "name": "wei lu",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "hui cai",
                "org": "vanderbilt university"
            },
            {
                "name": "ying zheng",
                "org": "centers for disease control and prevention"
            },
            {
                "name": "x o shu",
                "org": "vanderbilt university"
            },
            {
                "name": "wei zheng",
                "org": "vanderbilt university"
            },
            {
                "name": "qiuyin cai",
                "org": "vanderbilt university"
            }
        ],
        "venue": "Cancer Research",
        "year": 2012
    },
    "8UobVgZR": {
        "id": "8UobVgZR",
        "title": "Effect of total flavonoids of epimedium on the expression of peroxisome proliferator-activated receptor gamma in hyperlipemia rats",
        "abstract": "Objective To investigate the effect of total flavonoids of epimedium(TFE) on the expression of peroxisome proliferator-activated receptor gamma(PPARγ) in hyperlipemia rats. Methods Thirty-five male SD rats were randomly devided into groups of A(high-fat diet,26rats) and B(full diet,9rats).After establishment of rat models,group A was further randomly devided into 3 subgroups of A1(hyperlipemia model,8rats),A2(treated with TFE 100mg/d,9rats) and A3(treated with TFE 200mg/d,9rats).After 4 weeks,the expression level of PPARγ was measured in each group. Results Compared with group B,the levels of TG,TC and LDL-C in group A were significantly increased(P<0.01).After treated with TFE,the levels of TG and TC were lower than those in group A1(P<0.05),whereas the expression of PPARγ was dramatically elevated(P<0.01).Conclusion TFE plays an important role in protecting the function of endothelial cells by promoting the expression of PPARγ in hyperlipemia rats.",
        "keywords": [
            "Total flavonoids of epimedium",
            "Peroxisome proliferator-activated receptor gamma",
            "Hyperlipemia"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ",et al.Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing , CHINA"
            },
            {
                "name": "ZHAO Lingjie",
                "org": ",et al.Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing , CHINA"
            },
            {
                "name": "DONG Xiaolei",
                "org": ",et al.Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing , CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2011
    },
    "sGvlsxVl": {
        "id": "sGvlsxVl",
        "title": "The influence of total pioglitazone on the activity of serum superoxide dismutase and level of malonaldehyde in hyperlipemia rats",
        "abstract": "Objective To investigate the influence of pioglitazone on the activity of serum superoxide dismutase and level of malonaldehyde in hyperlipemia rats.Methods 26 male SD rats were randomly divided into the high-fat diet group(17) and full diet group(9).High-fat diet group were fed for 12 weeks,then 17 male SD rats were randomly divided into two groups: the hyperlipemia group(8),group of high hyperlipemia with pioglitazone(9).The group of pioglitazone was lavaged with pioglitazone 10 mg/kg every day.After 4 weeks of intervention with pioglitazone,the activity of serum superoxide dismutase and level of malonaldehyde were measured.Results The levels of TG,TC and LDL in hyperlipemic group(1.74 mmol/L,3.50 mmol/L,0.45 mmol/L) were significantly increased compared with full diet group(0.93 mmol/L,1.83 mmol/L,0.20 mmol/L) after 12 weeks(P<0.01),which indicates that the model of hyperlipemia has been established.Compared with the controls(247.40 U/ml),the activity of serum superoxide dismutase(640.72 U/ml)was elevated after the intervention with pioglitazone,while the level of malonaldehyde(2.46 nmol/ml) was decreased.Conclusion Pioglitazone plays an important role in protecting the function of endothelial cells by elevating the activity of serum superoxide dismutase and decreasing the level of malonaldehyde in hyperlipemia rats.",
        "keywords": [
            "malonaldehyde",
            "pioglitazone",
            "hyperlipemia",
            "superoxide dismutase"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": ".Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ".Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "YU Yu",
                "org": ".Department of Integrated Traditional and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Military Medical Journal of Southeast China",
        "year": 2011
    },
    "8cEI18jn": {
        "id": "8cEI18jn",
        "title": "Gods,humans and nature in The Ring",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "李正欣",
                "org": ""
            },
            {
                "name": "蔡慧",
                "org": ""
            },
            {
                "name": "何晓峰",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2010
    },
    "UcBfSLel": {
        "id": "UcBfSLel",
        "title": "N -methyl threonine analogues of deglycobleomycin A 2 : Synthesis and evaluation",
        "abstract": "The synthesis of 5 and its D-allo-threonine epimer 6 and the comparison of their DNA cleavage efficiency and selectivity with that of deglycobleomycin A(2) (3) are detailed. The studies illustrate that N-methylation of the L-threonine subunit within deglycobleomycin A(2) dramatically reduces the DNA cleavage efficiency (10-15-fold), weakens and nearly abolishes the inherent DNA cleavage selectivity, but has little effect on the inherent oxidation capabilities of the activated Fe(III) complexes. The results are consistent with a previously unrecognized prominent role for the threonine NH and the potential importance of a hydrogen bond to the Fe(III) hydroperoxide complex of bleomycin or a subsequent activated complex implicated in recent structural models. (C) 1997 Elsevier Science Ltd.",
        "keywords": [
            "hydrogen bond"
        ],
        "authors": [
            {
                "name": "dale l boger",
                "org": ""
            },
            {
                "name": "shuji teramoto",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1997
    },
    "4NfHYUGj": {
        "id": "4NfHYUGj",
        "title": "The Observation of Plasma Angiotensin Ⅱ,Plasma Aldosterone by Pressure Overload in Rats",
        "abstract": "Objective To study the relation between plasma angiotensin Ⅱ(AngⅡ) and plasma aldosterone (ALD) in rats with pressure overload.Methods The rat model with myocardial hypertrophy of congestive heart failure and pressure overload were established.Left ventricular mass index (LVMI) was observed.The levels of plasma AngⅡ and plasma ALD were measured by radioimmunoassay.Results LVMI level of the model group was obviously higher than that of the sham group(P<0.05). The levels of plasma AngⅡ and ALD in the model group were obviously higher than that in sham group(P<0.01).Conclusion The levels of plasma AngⅡ and plasma ALD in rats with congestion heart failure by pressure overload were increased. The mechanism of heart failure with left ventricular hypertrophy might be related with the upregulation of plasma AngⅡ and plasma ALD.",
        "keywords": [
            "plasma aldosterone",
            "pressure overload",
            "congestive heart failure",
            "plasma angiotensin Ⅱ",
            "myocardial hypertrophy"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA %%#Nanjing %%#"
            },
            {
                "name": "Shen Siyu",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA %%#Nanjing %%#"
            },
            {
                "name": "Dong Xiaolei",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA %%#Nanjing %%#"
            }
        ],
        "venue": "Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease",
        "year": 2010
    },
    "Tf0w4163": {
        "id": "Tf0w4163",
        "title": "Regulations of Acupuncture on Gene Expression of IRS1 and IRS2 of Hepatic Tissue in T2DM rats",
        "abstract": "Objective:To study the effect of acupuncture on mRNA expression of IRS1 and IRS2 of hepatic tissue in T2DM rats.Methods:Obese rats due to diet were injected in abdomen with small dose STZ to induce T2DM.Then these T2DM rats were stochastically divided into acupuncture,Glibenclamide and model group.After treatment for 4 weeks,FBS was examined with active blood sugar meter,FINS was examined by radioimmunoassav,mRNA of IRS1 and IRS2 of hepatic tissue were evaluated in real-time RT PCR,and normal rats were in control.Results:Serum levels of FBS and FINS in model group were higher than control,those in acupuncture group were obviously lower than model.which were closed to control.FBS in Glibenclamide groups was reduced obviously compared with model.Serum FINS in Glibenclamide was decreased in some degree,but significant difference was found between Glibenclamide and control.Compared with control,relative contents of IRS1 mRNA in model,acupuncture and Glibenclamide group were respectively 25%,2.83-folds and 1.23-folds,relative contents of IRS2 mRNA in model,acupuncture and Glibenclamide group were respectively 2.19-folds,4.84% and 4.59-folds.Conclusion:Abnormal mRNA expression of IRS1 and IRS2 of hepatic tissue may be one of Pathogenesis of T2DM.Acupuncture and Glibenclamide can upregulate IRS1mRNA expression of hepatic tissue in T2DM rats,but acupuncture is better than Glibenclamide.Acupuncture can depress IRS2mRNA expression,while Glibenclamide has no effect on it.",
        "keywords": [
            "acupuncture",
            "type 2 diabetes mellitus",
            "IRS2mRNA",
            "IRS1mRNA",
            "real-time RT PCR"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Najing University of Chinese Medicine,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YUAN Ai-hong",
                "org": "Najing University of Chinese Medicine,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WEI Qun-li",
                "org": "Najing University of Chinese Medicine,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LIU Zhi-cheng",
                "org": ""
            }
        ],
        "venue": "Chinese Archives of Traditional Chinese Medicine",
        "year": 2009
    },
    "yUzdstY2": {
        "id": "yUzdstY2",
        "title": "ALDH1A1 mRNA expression in association with prognosis of triple-negative breast cancer.",
        "abstract": "ALDH1 is a crucial element in the retinoic acid signaling pathway regulating the self-renewal and differentiation of normal stem cells, and may play an important role in cancer progression. However, research on ALDH1 gene expressionand breast cancer prognosis has yielded conflicting results. We evaluated the association between tumor tissue ALDH1A1/ALDH1A3 mRNA expression and triple-negative breast cancer (TNBC) prognosis in the Shanghai Breast Cancer Survival Study (SBCSS, N=463), Nashville Breast Health Study (NBHS, N=86), and Southern Community Cohort Study (SCCS, N=47). Gene expression was measured in RNA isolated from breast cancer tissues. In the SBCSS, higher ALDH1A1 mRNA level was associated with improved disease-free (HR=0.87, 95% CI: 0.80-0.95, per log unit change) and overall survival (HR=0.85, 95% CI: 0.78-0.93 per log unit change) independent of age at diagnosis, TNM stage and treatment. We replicated the findings for overall survival in the NBHS and SCCS (HR = 0.27, 95% CI: 0.10-0.73) and for disease-free survival by a meta-analysis of four publicly-available gene expression datasets (HR = 0.86, 95% CI: 0.76-0.97). No significant association was found for ALDH1A3.Our study suggests high expression of ALDH1A1 mRNA in tumor tissues may be an independent predictor of a favorable TNBC outcome.",
        "keywords": [
            "ALDH1",
            "mRNA expression",
            "prognosis",
            "triple-negative breast cancer"
        ],
        "authors": [
            {
                "name": "Yan Liu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "michelle l baglia",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Ying Zheng",
                "org": "Department of Cancer Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "william j blot",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Department of Cancer Prevention and Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China."
            },
            {
                "name": "Hui Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Sarah Nechuta",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Wei Zheng",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Qiuyin Cai",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA."
            }
        ],
        "venue": "Oncotarget",
        "year": 2015
    },
    "fDYYxzYT": {
        "id": "fDYYxzYT",
        "title": "Updated correlation of dendritic cells with rheumatoid arthritis",
        "abstract": "The dendritic cell(DC) has the most powerful function among the antigen presenting cells known hitherto,which stimulates naive T cells and plays a pivotal role in inducing T cell tolerance.The role of DC in rheumatoid arthritis(RA) has aroused more and more attention.This article reviews the role of DC in RA and the researches on the drug intervention in its treatment.",
        "keywords": [
            "Rheumatoid arthritis",
            "Immune tolerance",
            "Dendritic cell"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "P2JvAT9X": {
        "id": "P2JvAT9X",
        "title": "The Asp327Asn Polymorphism in the Sex Hormone-Binding Globulin Gene Modifies the Association of Soy Food and Tea Intake With Endometrial Cancer Risk",
        "abstract": "",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wang Hong Xu",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Jia-Rong Cheng",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yong-Bing Xiang",
                "org": ""
            },
            {
                "name": "Xiao Ou Shu",
                "org": ""
            }
        ],
        "venue": "Nutrition and Cancer-an International Journal",
        "year": 2008
    },
    "UvoZVLjl": {
        "id": "UvoZVLjl",
        "title": "Effect of Metoprolol on Change of Plasma Aldosterone,Myocardium Fibrosis and Myocardial in Rats with Remodeling Congestive Heart Failure",
        "abstract": "Objective:To investigate the effect of metoprolol on plasma aldosterone,myocardium fibrosis and reverse ventricular remodeling in rats with corgestive heart failure.Method:Male SD rats were randomly allocated to the Isopreternol(ISO)-induced chronic heart failure group(n=20)receiving two subcutaneous injections of 170mg ISO per kilogram of body and the healthy normal group(n=10)receiving two subcutaneous injections of 0.25ml normal saline.At 6th week,the LVEF was measured by echocardiogram,the remaining rats with LVEF≤45% were randomly divided into two groups:control group(n=10),metoprolol group 8 mg/kg/d(n=10).At 18th week,the HR,LVEF,LVEDP,LVSP were assessed.Aldosterone(ALD)in plasma were examined by radio-immunity method,and the mass ratio of heart ventricle and left ventricle to body was measured.Results:(1)Compared with the normal group,the HR,LVEDP and ALD in plasma were significantly increased(P<0.01).But LVSP and ±dp/dtmax were significantly decreased in the control group.(2)Compared with the control group,the HR,LVEDP,LVWI and ALD in plasma were decreased distinctly.The LVSP and ±dp/dtmax were increased distinctly in the metoprolol group(P<0.01).Conclusion:Metoprolol can inhibit ALD in plasma,improve heart function and reverse ventricular remodeling with congestive heart failure.",
        "keywords": [
            "Rat",
            "CHF",
            "Myocardial remodeling",
            "ALD",
            "Metoprolol"
        ],
        "authors": [
            {
                "name": "Cai Hui",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing "
            },
            {
                "name": "Li Zheng",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing "
            },
            {
                "name": "Guo Han",
                "org": ",et al Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,Nanjing "
            }
        ],
        "venue": "Chinese Journal of Microcirculation",
        "year": 2010
    },
    "0kQ6CHMV": {
        "id": "0kQ6CHMV",
        "title": "Progress of oxidized low density lipoprotein and atherosclerosis",
        "abstract": "Oxidized low density lipoprotein(ox-LDL) plays an important role in the pathogenesis of atherosclerosis.ox-LDL influences the mobidity and development of atherosclerosis through injuring endothelial cells,creating foam cells,regulating the generation of vascular smooth cells,and other ways.Treating with antioxidant is an important method of curing atherosclerosis.",
        "keywords": [
            "foam cells formation",
            "generation of vascular smooth cells",
            "oxidized low density lipoprotein",
            "antioxidant",
            "endothelial cells injury"
        ],
        "authors": [
            {
                "name": "XU Jia-yang",
                "org": "Nanjing University of TCM,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Nanjing University of TCM,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2011
    },
    "fD3lA3f1": {
        "id": "fD3lA3f1",
        "title": "Endostatin polymorphism 4349G/A(D104N) is not associated with aggressiveness of disease in postate cancer",
        "abstract": "Endostatin is an important inhibitory molecule which mediates the sequential steps involved in angiogenesis. Lower level or impaired function of endostatin is associated with a higher risk of developing malignant solid tumors and with a worse prognosis of the disease. The endostatin N104 polymorphism might be associated with an impaired ability to inhibit angiogenesis. We analyzed the tissues from 98 Caucasian prostate cancer patients for the presence of D104N polymorphism. The frequencies of homozygous 4349G/G(104D/D), and heterozygous 4349G/A(104D/N) were 83.67%(82/98) and 16.33%(16/98), respectively; no individuals were homozygous 4349A/A(104N/N). With the Fisher's exact test we found the genotype of D104N was not significantly related to age, tumor grade, PSA and clinical stage (P > 0.05). There was no difference in relapse free survival(RFS) or overall survival(OS) between patients with 104D/N and those with 104D/D (P = 0.8283, 0.3713 respectively). We concluded that endostatin polymorphism was not associated with the aggressiveness of prostate cancer in Caucasian patients. © 2005 - IOS Press and the authors. All rights reserved.",
        "keywords": [
            "endostatin",
            "polymorphism",
            "prostate cancer",
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Hecheng Li",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Eric Shinohara",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Carolyn Cao",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "ZuoFei Wang",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Ming Teng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Bo Lu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "Disease Markers",
        "year": 2005
    },
    "mwqzV5pA": {
        "id": "mwqzV5pA",
        "title": "Analyzing the Level of Malondialdehyde-Modified Low-Density Lipoproteins and Its Immune Complexes in Patients with Rheumatoid Arthritis",
        "abstract": "Aim To investigate malondialdehyde-modified (MDA) low-density lipoprotein (LDL), its immune complexes (LDL-IC) and blood lipid levels in patients with rheumatoid arthritis (RA), and to explore the mechanism of high incidence from cardiovascular disease in patients with RA. Methods 55 patients with RA, 13 of which had cardiovascular disease (CAD), 42 of which had simply RA, and 60 healthy controls were randomly chosen. Plasma MDA-LDL and its immune complexes (LDL-IC) levels were determined by enzyme linked immunosorbent assay (ELISA). Blood lipid levels and inflammatory markers were also studied. All data was subjected to statistical analysis. Results Compared with the control, plasma lipids and apolipoproteins levels in patients with RA remained unchanged, except that apolipoprotein B levels increased in RA patients (P<0.05); meanwhile no difference was found in plasma lipids and apolipoproteins concentrations between simple RA patients and RA patients with CAD. MDA-LDL level in RA with CAD, simple RA and control were 187.81±90.89 mg/L, 102.01±57.73 mg/L and 32.65±27.00 mg/L, respectively. LDL-IC level in the three groups were 2.58±1.69 AU, 1.87±0.74 AU and 1.21±0.38 AU, respectively. Compared with the control, MDA-LDL and LDL-IC levels increased in simple RA patients and RA patients with CAD (P<0.01), furthermore, MDA-LDL and LDL-IC levels in RA patients with CAD were both found significantly higher than those in simple RA (P<0.01 or 0.05). LDL-IC level was found related with C-reactive protein (r=0.301, P=0.026), and MDA-LDL level tended to be related with erythrocyte sedimentation rate (r=0.263, P=0.057). Conclusions MDA-LDL and LDL-IC were both increased in RA patients, and may play an important role in atherocslerosis.",
        "keywords": [
            "Atherosclerosis",
            "Oxidative Modification",
            "Immune Complex",
            "Rheumatoid Arthritis",
            "Low Density Lipopretein"
        ],
        "authors": [
            {
                "name": "HU Bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Army Hospital of the People's Liberation Army, Nanjing , China"
            },
            {
                "name": "WANG Jun-Jun",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Army Hospital of the People's Liberation Army, Nanjing , China"
            },
            {
                "name": "ZHANG Chun-Ni",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Army Hospital of the People's Liberation Army, Nanjing , China"
            },
            {
                "name": "Cai Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine, Nanjing General Army Hospital of the People's Liberation Army, Nanjing , China"
            }
        ],
        "venue": "Chinese Journal of Arteriosclerosis",
        "year": 2008
    },
    "SEHSOXBO": {
        "id": "SEHSOXBO",
        "title": "Study on Rregressing Left Ventricular Hypertrophy in Rat With Pressure Overload by Bu Shen Prescription",
        "abstract": "Objective:To observe the effects of Bu Shen Prescription on regressing left ventricular hypertrophy in rat with pressure overload. Methods:The model of left ventricular hypertrophy in rat with pressure overload by abdominal aortic constriction was used. 60 SD male rats were randomly divided into five groups: sham operation group, model group, captopril group, Bu Shen Prescription high dosage group and Bu Shen Prescription low dosage group. After treatment 4 weeks, it was observed that the changes of myocardial hypertrophy [left ventricular mass index (LVMI), left ventricular myocardium HE staining, left ventricular myocytes ultramicrostructure]. Results: LVMI in model group was increased significantly than that in sham operation group(P<0.01). LVMIs in captopril group, Bu Shen Prescription high dosage group and low dosage group were lower than that in model group(P<0.01). The changes of left ventricular myocardium HE staining and left ventricular myocytes ultramicrostructure were consistent with those of LVMI.Conclusions: Bu Shen Fu Prescription and captopril had the similar effect on regressing left ventricular hypertrophy.",
        "keywords": [
            "Ultramicrostructure",
            "Left ventricular hypertrophy",
            "Pressure overload",
            "Bu Shen Prescription"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            },
            {
                "name": "GUO Jun-hao",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            },
            {
                "name": "SHANG Wei",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            },
            {
                "name": "DONG Xiao-lei",
                "org": " Nanjing General Hospital of Nanjing Military Command, PLA, Nanjing,China,"
            }
        ],
        "venue": "Guiding Journal of Traditional Chinese Medicine and Pharmacy",
        "year": 2010
    },
    "x97DhBcK": {
        "id": "x97DhBcK",
        "title": "Prospective cohort studies of birth weight and risk of obesity, diabetes and hypertension in adulthood among Chinese population.",
        "abstract": "Background: Low birth weight (LBW) has been associated with subsequent risks of obesity and certain chronic diseases, but evidence for the associations is limited for the Chinese population. Methods: In this study we analyzed data from two population-based prospective cohort studies, the Shanghai Women's Health Study and the Shanghai Men's Health Study, to examine the associations between LBW and the risk of obesity and chronic diseases. Birth weight was self-reported at baseline; anthropometric measurements were made at study enrollment. Type 2 diabetes mellitus (T2DM) diagnoses were self-reported, whereas hypertension diagnoses were based on self-report and blood pressure measurements at baseline and follow-up surveys. Results: Birth weight was available for 11 515 men and 13 569 women. Non-linear associations were observed for birth weight with baseline body mass index (BMI), waist circumference (WC), waist: hip ratio (WHR), and waist: height ratio (WHtR; P < 0.05 for non-linearity), and LBW was linked with lower BMI, smaller WC, and larger WHR and WHtR. An excess risk of T2DM was observed for LBW (<2500 g) versus birth weight 2500-3499 g since baseline (hazard ratio [HR] 1.17; 95% confidence interval [CI] 0.92-1.49) and since birth (HR 1.29; 95% CI 1.07-1.54), whereas the HRs for hypertension since baseline and birth were 1.13 (95% CI 1.01-1.27) and 1.20 (95% CI 1.11-1.30), respectively. The risk of the diseases decreased as birth weight increased up to similar to 4000 g; further increases in birth weight did not convey additional benefits. Conclusion: The results suggest that LBW, an index of poor intrauterine nutrition, may affect health risks later in life in the Chinese population.",
        "keywords": [
            "birth weight",
            "hypertension",
            "obesity",
            "type 2 diabetes"
        ],
        "authors": [
            {
                "name": "Qinghua Xia",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, State Key Lab Oncogene & Related Genes, Renji Hosp, Shanghai Canc Inst,Sch Med, Shanghai, Peoples R China"
            },
            {
                "name": "Peng Zhou",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Honglan Li",
                "org": "Shanghai Jiao Tong Univ, State Key Lab Oncogene & Related Genes, Renji Hosp, Shanghai Canc Inst,Sch Med, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Yu Jiang",
                "org": "Ctr Dis Control & Prevent Changning Dist, Shanghai, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Dept Med, Vanderbilt Epidemiol Ctr,Div Epidemiol, Nashville, TN 37212 USA"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Fudan Univ, Sch Publ Hlth, Dept Epidemiol, Shanghai, Peoples R China"
            }
        ],
        "venue": "JOURNAL OF DIABETES",
        "year": 2019
    },
    "OcQ97f9K": {
        "id": "OcQ97f9K",
        "title": "Correlations of urinary phytoestrogen excretion with lifestyle factors and dietary intakes among middle-aged and elderly Chinese women.",
        "abstract": "Isoflavones and lignans, two major groups of phytoestrogens, have been postulated to have multiple health benefits, including anti-estrogenic, anti-cancer, pro-cardiovascular health, and ameliorating menopausal symptoms. Urinary excretion of isoflavonoids, including daidzein, genistein, glycitein, O-desmethylangolensin (O-DMA), dihydro-daidzein, dihydrogenistein, and equol, and lignans, including enterodiol and enterolactone, have been used as biomarkers of phytoestrogen exposure in epidemiologic studies. We evaluated the urinary excretion of phytoestrogens and their correlations with lifestyle and dietary factors among 2,165 women who participated in the Shanghai Women's Health Study (SWHS), a population-based prospective cohort study of 74,942 urban Chinese women aged 40-70 years at study enrollment (1996-2000). The medians (in nmol/mg creatinine) were: isoflavonoids, 17.13; daidzein, 5.57; genistein, 2.41; glycitein, 0.94; O-DMA, 1.52; dihydrodaidzein, 0.81; dihydrogenistein, 0.19; equol, 0.11; enterodiol, 0.30; and enterolactone, 1.18. These levels are 2- (enterodiol) to 126- (O-DMA) fold higher than levels among US women similar in age range with the exception of enterolactone, for which a similar level was observed for both populations. Urinary isoflavonoid excretion was higher among older women and women who engaged in regular exercise and significantly associated with soy food intake, but was inversely related to fruit intake. Urinary excretions of dihydrodaidzein, dihydrogenistein, equol, enterodiol, and enterolactone were inversely associated with body mass index (BMI). Urinary excretion of isoflavones correlated with soy food intake and healthy lifestyle but was inversely associated with fruit intake among middle-aged and elderly Chinese women. Our study adds important information to the rapidly growing body of research on the potential health benefits of phytoestrogens.",
        "keywords": [
            "lignans",
            "dietary intakes",
            "phytoestrogens",
            "isoflavonoids",
            "lifestyle factors",
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Xiaoyan Wu",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Hui Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qi Dai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Honglan Li",
                "org": "Medical Center of Fudan University(),Shanghai,China"
            },
            {
                "name": "Qiuyin Cai",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Gong Yang",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Adrian A Franke",
                "org": "University Hawaii Cancer Research Center(Cancer Research Center of Hawaii),Honolulu,United States"
            },
            {
                "name": "Wei Zheng",
                "org": "VA Medical Center(),,"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "VA Medical Center(),,"
            }
        ],
        "venue": "International journal of molecular epidemiology and genetics",
        "year": 2012
    },
    "qKFHoikc": {
        "id": "qKFHoikc",
        "title": "Menopausal symptoms among breast cancer patients: a potential indicator of favorable prognosis.",
        "abstract": "Menopausal symptoms have been suggested to be an indicator of better prognosis among patients treated for breast cancer, because women who experience these symptoms usually have a lower level of estrogen. We tested this hypothesis in a population-based, prospective cohort study involving 4,842 women with stage 0 to III primary breast cancer who were enrolled in the Shanghai Breast Cancer Survival Study between March 2002 and April 2006, were aged 20 to 75 years, and were recruited 6 months post-diagnosis. They were followed-up by in-person surveys and record linkages with the vital statistics registry. Cox regression analysis was used to evaluate the association of menopausal symptoms at baseline with breast cancer recurrence. Approximately 56% of patients experienced at least one menopausal symptom, including hot flashes, night sweats, and/or vaginal dryness at baseline. During a median follow-up period of 5.3 years, 720 women had a recurrence. Experiencing hot flashes or having ≥2 menopausal symptoms was associated with lower risk of recurrence among premenopausal women (hazard ratio [HR]=0.77, 95% confidence interval [CI]: 0.62-0.96 for hot flashes; 0.73, 0.56-0.96 for ≥2 menopausal symptoms). Lower recurrence risk in relation to hot flashes was also observed among women who were not overweight/obese (HR=0.78, 95% CI: 0.64-0.99), those with relatively low waist-to-hip ratio (WHR) (HR=0.77, 95% CI: 0.61-0.97), and those who used tamoxifen (HR=0.75, 95% CI: 0.58-0.98). Consistently experiencing multiple menopausal symptoms was associated with lower recurrence risk among women with low WHR or who used tamoxifen. This large, population-based cohort study of women with breast cancer confirms that experiencing menopausal symptoms is an indicator of favorable breast cancer prognosis.",
        "keywords": [
            "waist hip ratio",
            "engineering",
            "chemistry",
            "proportional hazards models",
            "radiation therapy",
            "china",
            "physics",
            "sweat",
            "breast cancer",
            "quality of life",
            "regression analysis",
            "biology",
            "medicine",
            "prospective studies",
            "cohort studies"
        ],
        "authors": [
            {
                "name": "Yong Chen",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Tsogzolmaa Dorjgochoo",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Institute of Preventive Medicine(Shanghai Institute of Preventive Medicine),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Institute of Preventive Medicine(Shanghai Institute of Preventive Medicine),Shanghai,China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Ingram Cancer Center(Vanderbilt-Ingram Cancer Center,Vanderbilt University,Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine),Nashville,United States"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "QOS2qT01": {
        "id": "QOS2qT01",
        "title": "Glial cell line-derived neurotrophic factor promotes neuron-like cell differentiation of mesenchymal stem cells",
        "abstract": "BACKGROUND: The ultimate purpose for inducing the bone marrow mesenchymal stem cells to differentiate into neuron-like cells in vitro is to transplant the induced cells into the body and repair the damaged nervous system. So, it is important to ensure the activity of the transplanted cells. OBJECTIVE: To investigate the protective effect of glial cell line-derived neurotrophic factor on neuron-likecells differentiated from mucaca multta bone marrow mesenchymal stem cells induced with cryptotanshinone in vitro. METHODS: The passage 8 mucaca multta bone marrow mesenchymal stem cells were induced with cryptotanshinone to differentiate into neuron-like cells, and the percentage of apoptosis of the induced cells at different time points after induction was detected with flow cytometry (0.5 hour was one group, a total of 12 hours). The period with higher apoptosis percentage was selected to observe the effect of different concentrations of glial cell line-derived neurotrophic factor (0-100 μg/L, totally eleven groups) on the apoptosis of the induced cells. RESULTS AND CONCLUSION: Cell apoptosis percentage after induction was increased gradually over time and reached a peak about 4 hours, and decreased after 1 hour (P<0.05). Cell apoptosis percentage was decreased gradually when the concentration of glial cell line-derived neurotrophic factor increased from 0 μg/L to 30 μg/L (P<0.05), and more remarkable change were not found when glial cell line-derived neurotrophic factor concentration reached 30 μg/L. The results show that glial cell line-derived neurotrophic factor has the protective effect on the neuron-like cells differentiated from mucaca multta bone marrow mesenchymal stem cells induced with cryptotanshinone in vitro.",
        "keywords": [
            "neuron-like cells",
            "apoptosis",
            "cryptotanshinone",
            "differentiation",
            "induction",
            "flow cytometry",
            "inducing agent",
            "mucaca multta",
            "stem cells",
            "glial cell line-derived neurotrophic factor",
            "stem cells and traditional Chinese medicine",
            "stem cell photographs-containing paper",
            "bone marrow mesenchymal stem cells"
        ],
        "authors": [
            {
                "name": "Liu Xiao-gang",
                "org": " Department of Pathology, Beijing Chuiyangliu Hospital, Beijing , China"
            },
            {
                "name": "Deng Yu-bin",
                "org": " Department of Pathology and Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou , Guangdong Province, China"
            },
            {
                "name": "Cai Hui",
                "org": " Department of Pathology, Beijing Chuiyangliu Hospital, Beijing , China"
            }
        ],
        "venue": "Chinese Journal of Tissue Engineering Research",
        "year": 2013
    },
    "mKNofw3c": {
        "id": "mKNofw3c",
        "title": "Atherosclerosis of rheumatoid arthritis and cholinergic anti-inflammatory pathway",
        "abstract": "Rheumatoid arthritis is an autoimmune disease,found in clinical cases in recent years.The incidence of RA patients developing cardiovascular disease was significantly higher than the normal population.Atherosclerosis is the main cause for the death of RA patients.In recent years,since the inflammation theory of atherosclerosis is established,people have realized that the process of inflammation maybe the important cause of atherosclerosis.Study find out that vagus nerve-mediated cholinergic anti-inflammatory pathway can inhibit the activation of the immune cells and the releasing of pro-inflammatory cytokines,to achieve the purpose of regulating inflammatory response,leading to an effective therapeutic approach to rheumatoid arthritis and atherosclerosis.",
        "keywords": [
            "cholinergic anti-inflammatory pathway",
            "cytokine",
            "rheumatoid arthritis",
            "atherosclerosis"
        ],
        "authors": [
            {
                "name": "LIU Chun-li",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command, Clinical School of Southern Medical University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command, Clinical School of Southern Medical University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2012
    },
    "iYbPNAvV": {
        "id": "iYbPNAvV",
        "title": "CBI-CDPBO 1 and CBI-CDPBI 1 : CC-1065 analogs containing deep-seated modifications in the DNA binding subunit",
        "abstract": "The synthesis and preliminary examination of CBI-CDPBO1 (2) and CBI-CDPBI1(3), CBI analogs of CC-1065 (1) and the duocarmycins incorporating the 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]benzoxazole-7- carboxylate (CDPBO) and 3-carbamoyl-1,2-dihydro-3 H-pyrrolo[3,2-e]benzimidazole-7-carboxyl (CDPBI) DNA binding subunits, are detailed. The agents contain deep-seated modifications in the DNA binding subunits of the natural products with incorporation of a nitrogen capable of functioning as a hydrogen bond acceptor (CDPBO, CDPBI) or hydrogen bond donor (CDPBI) on their inside concave face which is in intimate contact with the minor groove floor. The CDPBO subunit was prepared through use of a novel and effective MnO2- mediated oxidative coupling of 2-(benzyloxy)ethylamine with 5-hydroxyindole (4) to directly provide 2[(benzyloxy)methyl]pyrrolo[3,2-e]benzoxazole (6, 48%) in a reaction cascade that initially proceeds with amine regioselective C4 nucleophilic addition to the in situ generated p-quinone monoimine 13. Subsequent conversion of 6 to 8 (debenzylation; MnO2-NaCN, CH3OH) and selective reduction of the fused pyrrole (Et(3)SiH-CF3CO2H) completed the synthesis of the 1,2-dihydro-3H-pyrrolo[3,2-e]benzoxazole-7-carboxylate ring system. The CDPBI subunit was prepared through selective C4 nitration of 22 followed by reduction of the nitro group and acid-catalyzed closure to the corresponding 2-[(benzyloxy)methyl]pyrrolo[3,2e]benzimidazole 25. The final conversion of 25 to the 1,2-dihydro-3H-pyrrolo[3,2-e]benzimidazole-7-carboxylate ring system (CDPBI) followed the same protocols introduced for CDPBO. The DNA alkylation efficiencies of 2 and 3 were identical and both were substantially diminished relative to that of CBI-CDPI1 (40). Thus, the introduction of a single nitrogen atom in the DNA binding subunit of 40 has a pronounced and detrimental effect on the relative efficiency (100 x) of DNA alkylation. Consistent with these observations, the in vitro cytotoxic activity of (+)-2 and (+)-3 were comparable (IC50 200 pM, L1210) and 40 x less potent than (+)-40 (IC50 = 5 pM, L1210). In contrast to the large impact these small structural changes had on the effrciency of DNA alkylation, the selectivity of DNA alkylation by 2 and 3 was unperturbed and both agents were found to allcylate the same major sites as CBI-CDPI1 (40). The potential origin of these effects is discussed.",
        "keywords": [
            "structural change",
            "hydrogen bond",
            "nitrogen",
            "relative efficiency"
        ],
        "authors": [
            {
                "name": "dale l boger",
                "org": ""
            },
            {
                "name": "weiya yun",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "nianhe han",
                "org": ""
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 1995
    },
    "ViJ4IUaC": {
        "id": "ViJ4IUaC",
        "title": "Effect of pioglitazone on activity of NF-KB and expression of aorta apoptosis proteins in rats with hyperlipidemia",
        "abstract": "Objective To observe the effect of pioglitazone on activity of NF-icB,Bax and Bcl-2 in rats with hyperlipidemia.Methods Twenty-six male SD rats were randomly divided into control group(n=9) and high fat diet group(n=17).Rats in high fat diet group were further randomized into model group(n= 8) and pioglitazone group(n= 9) after fed with high fat diet for 12 weeks. Four weeks after intervention,serum lipid levels were measured and morphology of aortic tissue was observed with HE staining in different groups.Expressions of NF-κB p65,Bax and Bcl-2 in aortic tissue were analyzed by immunohistochemistry.Results The serum levels of lipid were significantly higher in high fat diet group after fed for 12 weeks(P<0.01).The serum levels of TG and TC were significantly lower in pioglitazone group than in model group with smooth and intact tunica intima of atorta and no significant proliferation of smooth muscle cells was found after fed for 16 weeks(P<0.01).The expression levels of NF-κB p65 and Bax were significantly higher in model group than in control group and significantly lower in pioglitazone group than in model group(P<0.01).The expression level of Bcl-2 and the ratio of Bcl-2 and Bax were significantly lower in pioglitazone group than in control group and significantly higher in-pioglitazone group than in model group(P<0.01).Conclusion High fat diet can change the expression of Bax and Bcl-2 in aorta,which may be related with the increased NF-κB activity.Pioglitazone can down-regulate the serum lipid level and the expression of NF-κB p65,and up-regulate the expression of Bax and Bcl-2,thus improving the function of endothelial cells and alleviating atherosclerosis.",
        "keywords": [
            "endothelial cells",
            "NF-kappa B",
            "hyperlipidemias",
            "gene expression",
            "atherosclerosis"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "CAI Hui",
                "org": "School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            },
            {
                "name": "ZHAO Ling-jie",
                "org": "School of Clinical Medicine,Southern Medical University,Nanjing ,Jiangsu Province,China"
            }
        ],
        "venue": "Chinese Journal of Geriatric Heart Brain and Vessel Diseases",
        "year": 2012
    },
    "bov2g5K7": {
        "id": "bov2g5K7",
        "title": "National Anthem:the melody contains people's struggles",
        "abstract": "A national anthem is a generally patriotic musical composition that evokes and eu- logizes the history,traditions and struggles of its people,recognized either by a nation's government as the official national song,or by convention through use by the people.There are almost 200 countries in the world,so there are as much national anthems. Some of the national anthems are marches,some are hymns or bal- lads.Most of them are inspiring, and parts of them are smooth.",
        "keywords": [],
        "authors": [
            {
                "name": "蔡慧",
                "org": ""
            }
        ],
        "venue": "Opera",
        "year": 2008
    },
    "kbCHs1Yr": {
        "id": "kbCHs1Yr",
        "title": "Changes of the expression of left ventricular myocardial angiotensin Ⅱ receptor type 1 mRNA and protein in rat with pressure overload",
        "abstract": "Objective To observe the expressions of left ventricular myocardial angiotensin(Ang) Ⅱ type 1(AT1) receptor mRNA and protein in rat with pressure overload,and to investigate the mechanism of left ventricular remodeling under pressure overload.Methods Rat models were constructed by placing a silver clip with internal diameter of 0.7 mm around the abdominal aorta above the renal arteries,then 24 SD male rats were randomly divided into sham operation group and model group.The changes of myocardial hypertrophy [left ventricular mass index(LVMI),left ventricular myocytes ultramicrostructure]was observed after 8 weeks.RT-PCR was used to detect the expression of left ventricular myocardial AT1 receptor mRNA,the change of myocardial AT1 receptor protein was observed by immunohistochemistry.Results LVMI in model group was significantly higher than that in sham operation group(P < 0.01).Left ventricular myocytes ultramicrostructure showed cardiocyte hypertrophy in heart tissue in the model group.The expressions of AT1 receptor mRNA and protein in left ventricular myocardial tissue in model group were significantly higher than those in sham operation group(P < 0.01).Conclusion The main physiopathologic changes of left ventricular remodeling were formed in the rat with pressure overload by abdominal aortic constriction after 8 weeks.The mechanism of left ventricular remodeling might be related to the expressions of AT1 receptor mRNA and protein in left ventricular myocardial tissue.",
        "keywords": [
            "AngiotensinⅡ receptor protein",
            "Ventricular remodeling",
            "Pressure overload"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHANG Yong-wen",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ".Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2010
    },
    "ANaw8B6D": {
        "id": "ANaw8B6D",
        "title": "Effects of MTX on the proliferation of rheumatoid arthritis' circum-citrullinated peptide antigen special T cell",
        "abstract": "Aim To observe the effects of MTX on the proliferation of rheumatoid arthritis'circum-citrullinated peptide antigen special T cell.Methods The rheumatoid arthritis'lymphocytes were cultured in vitro for 72 h,and divided into three groups:Lymphocyte(to abbreviate cell group),lymphocyte with CCP(Degree of enrichment 20 mg·L-1,to abbreviate CCP group)、lymphocyte with MTX(Degree of enrichment 20 mg·L-1,to abbreviate MTX group).The proliferation of lymphocytes' OD were measured by CCK-8.Results CCP can induce the proliferation of rheumatoid arthritis'lymphocytes(P<0.01).When added MTX,the proliferation of rheumatoid arthritis'CCP/AST were inhibited(P<0.01).Conclusion MTX can inhibit the proliferation of rheumatoid arthritis'CCP/AST.We conclude that MTX as the utility drugs of RA,its effects maybe come true by inhibiting the proliferation of the rheumatoid arthritis'CCP/AST.",
        "keywords": [
            "circum-citrullinated peptide antigen special T cell",
            "proliferation",
            "rheumatoid Arthritis",
            "citrullinated peptide",
            "MTX"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chineseand Western Medicine,Nanjing General Hospitalof Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chineseand Western Medicine,Nanjing General Hospitalof Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Integrated Traditional Chineseand Western Medicine,Nanjing General Hospitalof Nanjing Military Command,PLA,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Anhui Medical and Pharmaceutical Journal",
        "year": 2010
    },
    "nin7nj4n": {
        "id": "nin7nj4n",
        "title": "Novel edge detection method based on multiple information measures fusion",
        "abstract": "A novel edge detection method based on information measure concept and Dempster Shafer (DS) evidence theory was proposed for high noise image. Three information measures including neighborhood homogeneity information measure, direction information measure and structure information measure were used to characterize edge. Edge detection uncertainty was introduced to design mass functions based on the distribution of each information measure response and combine them by DS combination rule. Then pixels were classified into edge or off-edge according to combining decision rule. Detection results and Pratt figure of merit comparision show that the method can effectively distinguish between edge dots and noise dots and it has the same performance to classical edge detectors for low noise image, while offers superior denoising performance for high noise image.",
        "keywords": [
            "Data fusion",
            "Dempster Shafer evidence theory",
            "Image edge detection",
            "Information measure"
        ],
        "authors": [
            {
                "name": "Hui Cai",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHANG Guang-xin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Hao Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHOU Ze-kui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science)",
        "year": 2008
    },
    "lM2a9luS": {
        "id": "lM2a9luS",
        "title": "Effect of Xiaopi Yueyi formula on behavioral changes in rats with chronic fatigue syndrome",
        "abstract": "Objective:To explore and discuss the effect of Xiaopi Yueyi formula on behavioral changes in rats with chronic fatigue syndrome.Methods:24 rats were divided into group model(16 rats) and control(8 rats) at random,and after produced rats with chronic fatigue syndrome,half in the former were taken orally with Xiaopi Yueyi formula while the latter were taken equally normal saline,moreover,methods of Open-Field、tail suspend time and exhaust swimming time were estimated and evaluated.Results:After succeeding in chronic fatigue manifestation in rats of group model,number of parallel and vertical movement diminished markedly,furthermore,time of tail suspend and exhaust swimming prolonged apparently.Nevertheless,Xiaopi Yueyi formula could ameliorate significantly these parameters in rats(P<0.05).Conclusion:Xiaopi Yueyi formula could ameliorate significantly chronic fatigue syndrome in rats.",
        "keywords": [
            "Rat",
            "Behavioral changes",
            "Xiaopi Yueyi formula",
            "Chronic fatigue syndrome"
        ],
        "authors": [
            {
                "name": "ZHANG Jun-hui",
                "org": "Department of Pharmacy"
            },
            {
                "name": "HU Bing",
                "org": "Department of Chinese Integrative Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "SHEN Si-yu",
                "org": "Department of Chinese Integrative Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Chinese Integrative Medicine,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "rgtS2kbh": {
        "id": "rgtS2kbh",
        "title": "Effects of Bushen prescription on plasma endothelin and calcitonin gene-related peptide in rats with pressure overload",
        "abstract": "Objection:To observe the effects of Bushen prescription on plasma endothelin and calcitonin gene-related peptide(CGRP) in rats with pressure overload.Methods:Sixty male SD mice were randomly divided into 5 groups:sham group,model group,captopril group,high-dose Bushen prescription group and low-dose Bushen prescription group,with 12 mice in each group.Left ventricular mass index(LVMI),left ventricular myocardium HE staining,plasma endothelin(ET) and calcitonin gene-related peptide(CGRP) were measured in each group.Results:Compared with sham group,the LVMI,ET of model group increased but CGRP decreased.After treatment,ET decreased(P< 0.05) but CGRP increased markedly(P<0.05).Plasma ET/CGRP ratio was less than 1 in sham group obviously,that close to 1 in model group and obviously less than 1 in captopril group,high-dose and low-dose Bushen prescription.This tendency of changes positively related to LVH.Conclusion:Bushen prescription can protect myocardial cells of left ventricular hypertrophy caused by pressure overload through decreasing ET and increasing CGRP,and its effect is similar to captopril.",
        "keywords": [
            "calcitonin gene-related peptide",
            "Bushen prescription",
            "endothelin",
            "pressure overload",
            "left ventricular hypertrophy",
            "rat"
        ],
        "authors": [
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            },
            {
                "name": "ZHANG Yong-wen",
                "org": "Department of Integrated Chinese and Western Medicines,Nanjing General Hospital of Nanjing Military Region,Nanjing ,China"
            }
        ],
        "venue": "Journal of Shandong University of Traditional Chinese Medicine",
        "year": 2010
    },
    "Sxy6C8Es": {
        "id": "Sxy6C8Es",
        "title": "Expression of DAPK and calgranulin B in mucosa of Barrett's esophagus",
        "abstract": "Objective To investigate the differential expression of death-associated protein kinase(DAPK) and calgranulin B in three pathological types of Barrett's esophagus,and to compare expression of DAPK and calgranulin B before and after endoscopic treatment with ligation and mucosa resection.Methods Fifty-seven samples of patients with Barrett's esophagus were collected after ligation and endoscopic mucosal resection and biopsy sample one month after operation. Expression of DAPK and calgranulin B were analyzed by immunohistochemistry.Results There was no significant difference in expression of DAPK and calgronulin B among three pathological types of Barrett's esophagus.Calgranulin B showed a statistic difference before and after endoscopic treatment of Barrett's esophagus. Conclusion Ligation with endoscopic mucosal resection is an safe and effective therapeutic method against Barrett's esophagus.Calgranulin B may become an indicator to assess the therapeutic efficacy of Barrett's esophagus.",
        "keywords": [
            "Calgranulin B",
            "DAPK",
            "Barrett's esophagus",
            "Endoscopic mucosal resection"
        ],
        "authors": [
            {
                "name": "SHI Hong",
                "org": "Department of Endoscopy,Fujian Provincial Tumor Hospital,Fujian "
            },
            {
                "name": "JIANG Shengjun",
                "org": "Department of Minimally Invasive Surgery,Beijing Chuiyangliu Hospital"
            },
            {
                "name": "WANG Yongguang",
                "org": "Department of Minimally Invasive Surgery,Beijing Chuiyangliu Hospital"
            },
            {
                "name": "ZHOU Dong",
                "org": "Department of General Surgery,Fujian Provincial Tumor Hospital"
            },
            {
                "name": "CHEN Gang",
                "org": "Department of Pathology,Fujian Provincial Tumor Hospital"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Pathology,Beijing Chuiyangliu Hospital,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2010
    },
    "yN3ZsHqc": {
        "id": "yN3ZsHqc",
        "title": "Application of Quality of Life Scale to assessing quality of life in patients with coronary heart disease",
        "abstract": "Quality of Life Scale(QOLS) is an important measure of the impact of diseases on the effect of treatment and other variables affecting people's lives.A lot of instruments have been developed to assess the quality of life in patients with coronary heart disease.The review focuses on the assessment of the quality of life in patients with coronary heart disease by QOLS.",
        "keywords": [
            "Assessment",
            "Coronary heart disease",
            "Quality of life"
        ],
        "authors": [
            {
                "name": "LI Bao-shi",
                "org": "Department of Healthcare for Senior Officers"
            },
            {
                "name": "PAN Shi-yong",
                "org": "Department of Healthcare for Senior Officers"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing School of Clinical Medicine,Southern Medical University / Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "nzpnnOw9": {
        "id": "nzpnnOw9",
        "title": "Effect of Captopril on myocardial NF-κB p65 in rats with Pressure Overload",
        "abstract": "Objective To observe the impact of Captopril on cardiac NF-κB p65protein in pressure-overload rats.Methods Four weeks after operation of abdominal aorta constriction,rat models were successfully established and were treated with Captopril for 4weeks.At 8weeks after surgery,the heart weight index(HWI)and left ventricle/weight index(LVWI)were calculated.To study the myocardial histopathology and interstitial fibrosis with HE and Masson staining.To measure the collagen volume fraction(CVF)and perivascular collagen area(PVCA).Immunohistochemical analysis was used to measure the cardiac NF-κB protein levels.Results ①Compared with Sham group,HWI and LVWI were significantly increased in Model group(P <0.01);Compared with Model group,Captopril significantly decreased these indexes(P <0.01)。②Compared with Sham group,CVF and PVCA were significantly increased in Model group(P<0.01);Compared with Model group,Captopril significantly reduced these indicators(P<0.01)。③Compared with Sham group,cardiac NF-κB p65protein content were increased in Model group(P <0.01);Compared with Model group,Captopril significantly reduced the expression of NF-κB p65(P <0.01).Conclusion Captopril can reverse pressure-overload induced ventricular hypertrophy,may be associated with inhibition of cadiac NF-κB p65protein expression.",
        "keywords": [
            "Rats",
            "NF-kappa B",
            "Captopril",
            "Ventricular hypertrophy"
        ],
        "authors": [
            {
                "name": "ZHAO Ling-jie",
                "org": ""
            },
            {
                "name": "CHANG Wen-jing",
                "org": ""
            },
            {
                "name": "ZHAO Zhi-ming",
                "org": ""
            },
            {
                "name": "DONG Xiao-lei",
                "org": ""
            },
            {
                "name": "CAI Hui",
                "org": ""
            }
        ],
        "venue": "Shanxi Medical Journal",
        "year": 2013
    },
    "eDilMhut": {
        "id": "eDilMhut",
        "title": "Security-constrained line loss minimization in distribution systems with high penetration of renewable energy using UPFC",
        "abstract": "Focused on the challenges raised by the large-scale integration of renewable energy resources and the urgent goal of energy saving, a novel control scheme for the unified power flow controller (UPFC) series converter is proposed to achieve line loss reduction and security enhancement in distribution systems with a high penetration of renewable energy. Firstly, the line loss minimum conditions of a general distribution system with loop configurations are deduced. Secondly, security constraints including the permissible voltage range, the line loading limits and the UPFC ratings are considered. System security enhancement with the least increase in line loss is tackled by solving a much reduced optimal power flow (OPF) problem. The computational task of the OPF problem is reduced by deducing the security-constrained line loss minimum conditions and removing the equality constraints. Thirdly, a hybrid control scheme is proposed. Line loss minimization is achieved through a dynamic controller, while an OPF calculator is integrated to generate corrective action for the dynamic controller when the security constraints are violated. The validity of the proposed control strategies is verified in a modified IEEE 33 bus test system.",
        "keywords": [
            "Line loss minimization",
            "Security enhancement",
            "Unified power flow controller (UPFC)",
            "Renewable energy"
        ],
        "authors": [
            {
                "name": "Pengcheng Song",
                "org": "Zhejiang University,Department of Electrical Engineering,Hangzhou,China"
            },
            {
                "name": "Zheng Xu",
                "org": "Zhejiang University,Department of Electrical Engineering,Hangzhou,China"
            },
            {
                "name": "Huanfeng Dong",
                "org": "Zhejiang University,Department of Electrical Engineering,Hangzhou,China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Zhenjian Xie",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            }
        ],
        "venue": "Modern power systems",
        "year": 2017
    },
    "fAPjkL6o": {
        "id": "fAPjkL6o",
        "title": "Effects of Sinomenine on Secreting IFN-γ and IL-4 of T Cell from Rheumatoid Arthritis Activated by Cyclic Citrullinated Peptide",
        "abstract": "Objective: To observe effects of sinomenine on the secreting IFN-γ and IL-4 of T cell from rheumatoid arthritis activated by cyclic citrullinated peptide.Methods: Peripheral blood lymphocyte(PBL) of 24 RA patients were cultured in vitro.All bodies were divided into the blank control group,the cyclic citrulline peptide group,the methotrexate group and the sinomenine group.After cultured respectively in vitro for 72 h,the concentrations such as IFN-γ and IL-4 were measured by ELISA.Results: Compared with the blank control group,concentration of IFN-γ from cyclic citrulline peptide group was increased obviously.After being used the sinomenine,the IFN-γ level was decreased significantly.The IL-4 in the cyclic citrulline group was less than that in the blank control group.However,its level was increased remarkably.Conclusion: The IL-4 and the IFN-γ are important in the rheumatoid arthritis treatment which are activated by the cyclic citrullinated peptide adjusting by the sinomenine.",
        "keywords": [
            "T cell",
            "Rheumatoid arthritis",
            "IFN-γ",
            "Sinomenine",
            "Cyclic citrullinated peptide",
            "IL-4"
        ],
        "authors": [
            {
                "name": "YAO Ru-bing",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu,Nanjing,"
            },
            {
                "name": "GAO Pei-fang",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu,Nanjing,"
            },
            {
                "name": "CAI Hui",
                "org": ".Nanjing General Hospital of Nanjing Military Command,PLA,Jiangsu,Nanjing,"
            }
        ],
        "venue": "Journal of Emergency in Traditional Chinese Medicine",
        "year": 2012
    },
    "dAlA3rPQ": {
        "id": "dAlA3rPQ",
        "title": "Changes of myocardial collagen type Ⅰ and type Ⅲ in rat models of abdominal aorta coarctation and their mRNA expressions",
        "abstract": "Objective:To investigate collagen type Ⅰ and type Ⅲ and their mRNA expression in rat models of abdominal aorta coarctation.Methods:14 of 30 SD rats were taken out randomly as sham operation group,and another 16 rats were selected as model group.Rat models were established by partially banding abdominal aorta with silver clip(0.7 mm of inside diameter) according to methods used by Doering's.Eight weeks later,collagen type Ⅰ and type Ⅲ were stained by immunohistochemistry and the optical density values were measured subsequently as a marker of their content.The mRNA expression levels of collagen type Ⅰ and type Ⅲ were analyzed after real-time PCR amplification.Results:In the 8th week,average optical density values and the mRNA expression levels of collagen type Ⅰ and type Ⅲ in model group increased significantly compared with sham operation group(P<0.01).Immunohistochemistry stain displayed that collagen typeⅠ and type Ⅲ in myocardium stroma of model group increased,thickened and disorganized remarkably.Conclusion:The mRNA expressions of collagen type Ⅰ and type Ⅲ in fibrotic myocardium induced by abdominal aorta coarctatio appear to increase mainly in intercellular substance and perivascular space.This model is suitable to study myocardial fibrosis during chronic process of some diseases,such as heart failure,hypertension and so on.",
        "keywords": [
            "gene expression",
            "abdominal aortic banding",
            "myocardial fibrosis",
            "type Ⅰ and type Ⅲ collagen"
        ],
        "authors": [
            {
                "name": "DONG Xiao-lei",
                "org": " Department of Integrated Traditional and Western Medicine,General Hospital of Nanjing Military Command,Nanjing,,China."
            },
            {
                "name": "JIAO Dong-dong",
                "org": " Department of Integrated Traditional and Western Medicine,General Hospital of Nanjing Military Command,Nanjing,,China."
            },
            {
                "name": "ZHAO Ling-jie",
                "org": " Department of Integrated Traditional and Western Medicine,General Hospital of Nanjing Military Command,Nanjing,,China."
            },
            {
                "name": "SHEN Si-yu",
                "org": " Department of Integrated Traditional and Western Medicine,General Hospital of Nanjing Military Command,Nanjing,,China."
            },
            {
                "name": "CAI Hui",
                "org": " Department of Integrated Traditional and Western Medicine,General Hospital of Nanjing Military Command,Nanjing,,China."
            }
        ],
        "venue": "Medical Journal of National Defending Forces in Southwest China",
        "year": 2009
    },
    "XgEKaEDW": {
        "id": "XgEKaEDW",
        "title": "Study on Transient Stability Constrained Optimal Power Flow Model of VSC-MTDC Transmission System Based on Phase Trajectory Concavity-convexity",
        "abstract": "This paper proposes a transient stability constrained optimal power flow model of VSC-MTDC transmission system. Using the concept of transient stability margin based on phase-plane trajectory concavity-convexity, the transient stability constraints are converted to generator active power constraints. Combined with the traditional optimal power flow model and constraints of VSC-MTDC system, the transient stability constrained optimal power flow model can be established. The optimization procedure is also given. According to the desired value of transient stability margin, the optimal generator active power output can be determined. The simulation results in the modified New England 39-bus system validate the effectiveness of the proposed method.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhuyi Peng",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Hui Cai",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Xingning Han",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Bailiang Liu",
                "org": "State Grid Jiangsu Economic Research Institute,Nanjing,China"
            },
            {
                "name": "Chaonan Ying",
                "org": "Zhejiang University, Department of Electrical Engineering, Hangzhou, China"
            },
            {
                "name": "Zheng Xu",
                "org": "Zhejiang University, Department of Electrical Engineering, Hangzhou, China"
            }
        ],
        "venue": "ieee pes asia pacific power and energy engineering conference",
        "year": 2019
    },
    "RY8kEp1v": {
        "id": "RY8kEp1v",
        "title": "Abstract 646: Soy food intake and risk of lung cancer: Evidence from the Shanghai Women's Health Study and a meta-analysis",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei zheng",
                "org": ""
            },
            {
                "name": "y gao",
                "org": ""
            },
            {
                "name": "shenghui wu",
                "org": ""
            },
            {
                "name": "hui cai",
                "org": ""
            },
            {
                "name": "butian ji",
                "org": ""
            },
            {
                "name": "honglan li",
                "org": ""
            },
            {
                "name": "xianglan zhang",
                "org": ""
            },
            {
                "name": "g yang",
                "org": ""
            },
            {
                "name": "xiaoou shu",
                "org": ""
            },
            {
                "name": "wongho chow",
                "org": ""
            }
        ],
        "venue": "Cancer Research",
        "year": 2012
    },
    "mFNoGXr5": {
        "id": "mFNoGXr5",
        "title": "Observation of ultralong valley lifetime in WSe2/MoS2 heterostructures",
        "abstract": "The valley degree of freedom in two-dimensional (2D) crystals recently emerged as a novel information carrier in addition to spin and charge. The intrinsic valley lifetime in 2D transition metal dichalcogenides (TMD) is expected to be markedly long due to the unique spin-valley locking behavior, where the intervalley scattering of the electron simultaneously requires a large momentum transfer to the opposite valley and a flip of the electron spin. However, the experimentally observed valley lifetime in 2D TMDs has been limited to tens of nanoseconds thus far. We report efficient generation of microsecond-long-lived valley polarization in WSe2/MoS2 heterostructures by exploiting the ultrafast charge transfer processes in the heterostructure that efficiently creates resident holes in the WSe2 layer. These valley-polarized holes exhibit near-unity valley polarization and ultralong valley lifetime: We observe a valley-polarized hole population lifetime of more than 1 ms and a valley depolarization lifetime (that is, intervalley scattering lifetime) of more than 40 mu s at 10 K. The near-perfect generation of valley-polarized holes in TMD heterostructures, combined with ultralong valley lifetime, which is orders of magnitude longer than previous results, opens up new opportunities for novel valleytronics and spintronics applications.",
        "keywords": "",
        "authors": [
            {
                "name": "Jonghwan Kim",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Chenhao Jin",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Tao Zhao",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Puiyee Lee",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Salman Kahn",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Kenji Watanabe",
                "org": "Natl Inst Mat Sci, 1-1 Namiki, Tsukuba, Ibaraki 3050044, Japan"
            },
            {
                "name": "Takashi Taniguchi",
                "org": "Natl Inst Mat Sci, 1-1 Namiki, Tsukuba, Ibaraki 3050044, Japan"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Michael F. Crommie",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            },
            {
                "name": "Feng Wang",
                "org": "Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA"
            }
        ],
        "venue": "SCIENCE ADVANCES",
        "year": 2017
    },
    "KDO3OBLF": {
        "id": "KDO3OBLF",
        "title": "Effects of Pioglitazone on Expression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 and Apoptosis Protein in Aorta of Hyperlipidemia Rats",
        "abstract": "Aim To investigate effects of pioglitazone on the expression of lectin-like oxidized low-density lipoprotein receptor-1(LOX-1) and Bax,Bcl-2 in aorta of hyperlipidemia rats,and also to study the possible mechanism of pioglitazone,the effects of LOX-1 on pioglitazone regulating Bax,Bcl-2 expression.Methods 26 male SD rats were randomly divided into control group(n=9) and high-fat diets group(n=17).High-fat diets group raised for 12 weeks were randomly divided into model group(n=8) and pioglitazone treated group(n=9).After 4 weeks,serum lipid level of all rats was measured,HE staining was used to observe aortic pathological changes.LOX-1 and apoptosis protein of Bax,Bcl-2 in the aorta were analyzed by immunohistochemical method.Results After 12 weeks,the serum lipid level was significantly higher in high-fat diets group(P<0.01).Intervention with pioglitazone for 4 weeks,compared with modle group,serum levels of triglyceride(TG),total cholesterol(TC) was decreased(P<0.01),and aortal endothelial tissue was intact,proliferation of smooth muscle cells were few in pioglitazone treated group.Compared with control group,the expression of LOX-1 and Bax protein in aorta were significantly increased(P<0.01),the Bcl-2 protein and ra-tio of Bcl-2/Bax was markedly decreased in model group(P<0.01).On the other hand,compared with model group,the expression of LOX-1 and Bax protein were lower,the Bcl-2 protein and ratio of Bcl-2/Bax were prominently higher in the pioglitazone treated group.Conclusions High-fat diets have an effect on expression of LOX-1 and apoptosis protein Bax and Bcl-2 in aorta,while pioglitazone can regulate the expression of LOX-1 and apoptosis protein,protecting endothelial from damage and apoptosis,improving the process of atherosclerotic pathological formation.",
        "keywords": [
            "Atherosclerosis",
            "Bax",
            "Pioglitazone",
            "Hyperlipidemia",
            "Bcl-2",
            "Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1"
        ],
        "authors": [
            {
                "name": "LI Rong",
                "org": "School of Clinical Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,China"
            },
            {
                "name": "Cai Hui",
                "org": "School of Clinical Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,China"
            },
            {
                "name": "DONG Xiao-Lei",
                "org": "School of Clinical Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Ling-Jie",
                "org": "School of Clinical Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,China"
            },
            {
                "name": "ZHAO Zhi-Ming",
                "org": "School of Clinical Medicine,Southern Medical University&Nanjing General Hospital of Nanjing Military Region,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Chinese Journal of Arteriosclerosis",
        "year": 2012
    },
    "XAxVKOdS": {
        "id": "XAxVKOdS",
        "title": "Effects of Reinforcing Kidney Compound on mRNA Expressions of Myocardial α-myosin Heavy Chain and β-myosin Heavy Chain in Rats with Pressure Overload",
        "abstract": "Objective: To investigate the effects of reinforcing kidney compound on the mRNA expressions of myocardial α-myosin heavy chain(α-MHC) and β-myosin heavy chain(β-MHC) in rat with pressure overload so as to explore the mechanism of its reversing left ventricular hypertrophy.Methods: The male SD rats were randomly divided into sham operation group,model group,captopril group,reinforcing kidney compound high-dose group and reinforcing kidney compound low-dose group.After 4 weeks of modeling,the rats were given drug intervention for 4 weeks.The expressions of α-MHC and β-MHC in myocardial tissue were detected by RT-PCR.Results: The α-MHC mRNA expression of left ventricular myocardial tissue in model group was significantly lower than that in sham operation group(P<0.05).The α-MHC mRNA expression of captopril group,reinforcing kidney compound high-dose group and low-dose group were significantly higher than that in model group(P<0.05,P<0.01).The β-MHC mRNA expression of left ventricular myocardial tissue in model group was increased than that in sham operation group(P<0.05).The β-MHC mRNA expression of captopril group,reinforcing kidney compound high-dose group and low-dose group was lower than that in model group(P<0.05).Conclusion: Reinforcing kidney compound can reverse the myocardial hypertrophy which was related to increasing the expression of α-MHC and decreasing the expression of β-MHC.",
        "keywords": [
            "β-MHC",
            "Myocardial hypertrophy",
            "gene expression",
            "pressure overload",
            "α-MHC",
            "reinforcing kidney compound"
        ],
        "authors": [
            {
                "name": "ZHAO Zhi-ming",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            },
            {
                "name": "ZHANG Qun-yan",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            },
            {
                "name": "DONG Xiao-lei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            },
            {
                "name": "GUO Jun-hao",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            },
            {
                "name": "SHANG Wei",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine,Nanjing General Hospital of Nanjing Military Command"
            }
        ],
        "venue": "Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai",
        "year": 2010
    },
    "FmZniTEX": {
        "id": "FmZniTEX",
        "title": "A Novel Voltage Regulation Strategy for Secure Operation of High Renewable Penetrated Distribution Networks with Different R/X and Topologies",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Qian Hu",
                "org": "Department of Electrical Engineering , The Hong Kong Polytechnic University "
            },
            {
                "name": "Siqi Bu",
                "org": "Department of Electrical Engineering , The Hong Kong Polytechnic University "
            },
            {
                "name": "Shiwei Xia",
                "org": "School of Electrical and Electronic Engineering|North China Electric Power University"
            },
            {
                "name": "Hui Cai",
                "org": "Jiangsu State Grid Economic Research Institute"
            }
        ],
        "venue": "ieee innovative smart grid technologies asia",
        "year": 2019
    },
    "eItI6nym": {
        "id": "eItI6nym",
        "title": "Comorbidities and breast cancer survival: a report from the Shanghai Breast Cancer Survival Study.",
        "abstract": "We investigated the association of major comorbidities with breast cancer outcomes using the Shanghai Breast Cancer Survival Study, a population-based, prospective cohort study of Chinese women diagnosed with breast cancer. Analyses included 4,664 women diagnosed with stage I-III incident breast cancer aged 20-75 years (median age = 51) during 2002-2006. Women were interviewed at 3-11 months post-diagnosis (median = 6.4) and followed up by in-person interviews and linkage with the vital statistics registry. Multivariable hazard ratios (HRs) and (95 % confidence intervals (CIs)) for the associations of comorbidities with breast cancer outcomes were estimated using Cox regression models. After a median follow-up of 5.3 years (range: 0.64-8.9), 647 women died (516 from breast cancer) and 632 recurrence/metastases were documented. The main comorbidities reported included: hypertension (22.4 %), chronic gastritis (14.3 %), diabetes mellitus (6.2 %), chronic bronchitis/asthma (5.8 %), coronary heart disease (5.0 %), and stroke (2.2 %). Diabetes was associated with increased risk of total mortality (adjusted HR: 1.40 (1.06-1.85)) and non-breast cancer mortality (adjusted HR: 2.64 (1.63-4.27)), but not breast cancer-specific mortality (adjusted HR: 0.98 (0.68-1.41)), adjusting for socio-demographics, clinical characteristics, selected lifestyle factors, and other comorbidities. Women with a history of stroke had a non-significant increased risk of total mortality (adjusted HR: 1.42 (0.91-2.22)) and a significant increased risk of non-breast cancer mortality (adjusted HR: 2.52 (1.33-4.78)), but not breast cancer-specific mortality (adjusted HR: 0.78 (0.38-1.62)). Overall, none of the comorbidities investigated were significantly associated with recurrence. In this large prospective cohort of breast cancer survivors, diabetes was significantly associated with increased risk of total and non-breast cancer mortality, and history of stroke was associated with increased risk of non-breast cancer mortality.",
        "keywords": [
            "breast cancer",
            "comorbidity",
            "prognosis",
            "survival"
        ],
        "authors": [
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wei Lu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Center for Disease Control and Prevention(Shanghai Municipal Center for Disease Control and Prevention),Shanghai,China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            }
        ],
        "venue": "Breast cancer research and treatment",
        "year": 2013
    },
    "hPJSf3Am": {
        "id": "hPJSf3Am",
        "title": "Pyrazole-based cathepsin S inhibitors with improved cellular potency.",
        "abstract": "Noncovalent, pyrazole-based cathepsin S inhibitors are reported. Significant improvements in cellular potency were achieved through modification of a 4-(indol-3-yl)piperidine head group.",
        "keywords": [
            "Cathepsin S",
            "Antigen processing",
            "Enzyme inhibitor"
        ],
        "authors": [
            {
                "name": "Jianmei Wei",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Barbara A Pio",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Hui Cai",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Steven P Meduna",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Siquan Sun",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Yin Gu",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Wen Jiang",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Robin L Thurmond",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "Lars Karlsson",
                "org": "Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA"
            },
            {
                "name": "James P Edwards",
                "org": "Corresponding author. Tel.: +1 858 450 2024; fax: +1 858 784 3116."
            }
        ],
        "venue": "Bioorganic & Medicinal Chemistry Letters",
        "year": 2007
    },
    "zJ8DRnw2": {
        "id": "zJ8DRnw2",
        "title": "Abnormal characteristics of plasma lipid levels in patients with rheumatoid arthritis",
        "abstract": "Objective: To explore the mechanism of high incidence of cardiovascular diseases and the levels of plasma lipids and oxidized lowdensity lipoprotein(Ox-LDL) in patients with rheumatoid arthritis(RA).Methods: Fifty-five patients with RA(24 case of active type,31 non-active) and 60 healthy controls were randomly chosen.Plasma lipids and Ox-LDL levels were studied.All the data were subjected to statistical analysis.Results: Compared with the control,total cholesterol(TC),LDL cholesterol(LDL-C) and apolipoprotein B(apoB) levels were increased in patients with active RA,while TC,triglyceride(TG),LDL-C,apoAⅠ,B and Ox-LDL levels were elevated in those with non-active RA.Furthermore,plasma lipids and Ox-LDL level decreased in the active patients as compared with the non-active ones,while only the change of apoAⅠhad statistical significance.The erythrocyte sedimentation rate was found negatively related with TC,LDL-C,high-density lipoprotein cholesterol(HDL-C) and apoAⅠ,while C-reacting protein was found negatively related with LDL-C and HDL-C.Conclusion: Ox-LDL and plasma lipid levels were changed in RA patients.Inflammation may induce changes of lipoprotein and play an important role in atherosclerosis.",
        "keywords": [
            "Atherosclerosis",
            "LDL",
            "Rheumatoid arthritis",
            "Oxidative modification",
            "Immune complex"
        ],
        "authors": [
            {
                "name": "HU Bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "WANG Jun-jun",
                "org": "Institute of Clinical Laboratory Medicine of PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YAO Ru-bing",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "CAI Hui",
                "org": "Department of Integrated Traditional Chinese and Western Medicine"
            },
            {
                "name": "ZHANG Chun-ni",
                "org": "Institute of Clinical Laboratory Medicine of PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2007
    },
    "SMjnOZdv": {
        "id": "SMjnOZdv",
        "title": "Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival.",
        "abstract": "Background Estrogen plays a central role in the development and progression of breast cancer. The estrogen's effects are at least partially regulated by estrogen-metabolizing enzymes. The objective of the study is to investigate associations of breast cancer survival with genetic polymorphisms in several genes involved in estrogen-metabolism (CYP1A1, CYP1A2, CYP1B1, COMT, and AhR). Methods A cohort of 1140 patients aged between 25 and 64 years at the time of diagnosis for primary breast cancer during 1996-1998 were included in the study. Patients were followed for cancer recurrence and mortality through July 2005. Results Associations were observed at rs4680 (Met158Val) in the COMTgene and rs4646903 (CYP1A1*2A) in the CYP1A1 gene. The adjusted hazard ratio for the rs4680 AA genotype (low enzyme activity genotype) was 1.6 (95% confidence interval, 1.1-2.4) compared with the GG genotype for disease-free survival. Adjusted hazard ratios for the rs4646903 CC genotype were 1.6 (95% confidence interval, 1.2-2.2) for disease-free survival and 1.4 (95% confidence interval, 1.0-2.1) for overall survival compared with the TT genotype. No apparent association was found for any of the other six single nucleotide polymorphisms evaluated in the AhR, CYP1A1, CYP1A2, and CYP1B1 genes. Conclusion Results from this study suggest that rs4680 in the COMTgene and rs4646903 in the CYP1A1 gene may be genetic markers for breast cancer prognosis in Chinese women.",
        "keywords": [
            "breast cancer",
            "estrogen metabolism",
            "single nucleoticle polymorphism",
            "survival"
        ],
        "authors": [
            {
                "name": "Ji-Rong Long",
                "org": ""
            },
            {
                "name": "Qiuyin Cai",
                "org": ""
            },
            {
                "name": "Xiao-Ou Shu",
                "org": ""
            },
            {
                "name": "Hui Cai",
                "org": ""
            },
            {
                "name": "Yu-Tang Gao",
                "org": ""
            },
            {
                "name": "Wei Zheng",
                "org": ""
            }
        ],
        "venue": "PHARMACOGENETICS AND GENOMICS",
        "year": 2007
    },
    "7SHrdSxG": {
        "id": "7SHrdSxG",
        "title": "A prospective study of autoantibodies to Ezrin and pancreatic cancer risk",
        "abstract": "No biomarker is available for pancreatic cancer early detection, but a small prospective European study involving 16 cases and 32 controls raised the possibility that anti-Ezrin autoantibodies may be associated with risk of pancreatic cancer. We aimed to validate this finding in a case-control study nested within a prospective study in the USA. Levels of anti-Ezrin autoantibodies were examined using ELISA in pre-diagnostic plasma samples of 73 cases and 145 matched controls. Paired t test and paired signed rank tests were used to determine the difference between two groups, and conditional logistic regression was used to evaluate the association between anti-Ezrin autoantibody levels and risk of developing pancreatic cancer. No association was found between levels of anti-Ezrin plasma autoantibodies and subsequent risk of developing pancreatic cancer. Anti-Ezrin autoantibodies did not appear to be useful as a plasma biomarker for early detection of pancreatic cancer.",
        "keywords": [
            "Ezrin",
            "Autoantibodies",
            "Pancreatic cancer risk",
            "Prospective study"
        ],
        "authors": [
            {
                "name": "Yaqiong Sun",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Yaqiong Sun",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Jie Wu",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Shuyang Wang",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Qiaolan Liu",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Qiaolan Liu",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "William J. Blot",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt University School of Medicine"
            }
        ],
        "venue": "CANCER CAUSES & CONTROL",
        "year": 2016
    },
    "VzZvyVzj": {
        "id": "VzZvyVzj",
        "title": "Domain Architectures and Grain Boundaries in Chemical Vapor Deposited Highly Anisotropic ReS2 Monolayer Films",
        "abstract": "Recent studies have shown that vapor phase synthesis of structurally isotropic two-dimensional (2D) MoS2 and WS2 produces well-defined domains with clean grain boundaries (GBs). This is anticipated to be vastly different for 2D anisotropic materials like ReS2 mainly due to large anisotropy in interfacial energy imposed by its distorted 1T crystal structure and formation of signature Re-chains along [010] b-axis direction. Here, we provide first insight on domain architecture on chemical vapor deposited (CVD) ReS2 domains using high-resolution scanning transmission electron microscopy, angle-resolved nano-Raman spectroscopy, reflectivity, and atomic force microscopy measurements. Results provide ways to achieve crystalline anisotropy in CVD ReS2, establish domain architecture of high symmetry ReS2 flakes, and determine Re-chain orientation within subdomains. Results also provide a first atomic resolution look at ReS2 GBs, and surprisingly we find that cluster and vacancy defects, formed by collusion of Re-chains at the GBs, dramatically impact the crystal structure by changing the Re-chain direction and rotating Re-chains 180 along their b-axis. Overall results not only shed first light on domain architecture and structure of anisotropic 2D systems but also allow one to attain much desired crystalline anisotropy in CVD grown ReS2 for the first time for tangible applications in photonics and optoelectronics where direction-dependent dichroic and linearly polarized material properties are required.",
        "keywords": [
            "2D materials",
            "ReS2",
            "anisotropic materials",
            "chemical vapor deposition",
            "grain boundary",
            "synthesis"
        ],
        "authors": [
            {
                "name": "Kedi Wu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Bin Chen",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Sijie Yang",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Gang Wang",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Av Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Wilson Kong",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Hui Cai",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Toshihiro Aoki",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Emmanuel Soignard",
                "org": "Arizona State Univ, LeRoy Eyring Ctr Solid State Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "X. Marie",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Av Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Aliya Yano",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "Aslihan Suslu",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            },
            {
                "name": "B. Urbaszek",
                "org": "Univ Toulouse, INSA CNRS UPS, LPCNO, 135 Av Rangueil, F-31077 Toulouse, France"
            },
            {
                "name": "Sefaattin Tongay",
                "org": "Arizona State Univ, Sch Engn Matter Transport & Energy, Tempe, AZ 85287 USA"
            }
        ],
        "venue": "NANO LETTERS",
        "year": 2016
    },
    "HnMNXVQY": {
        "id": "HnMNXVQY",
        "title": "Soy Food Consumption, Exercise, and Body Mass Index and Osteoporotic Fracture Risk Among Breast Cancer Survivors: The Shanghai Breast Cancer Survival Study.",
        "abstract": "Background: Breast cancer survivors have a high incidence of osteoporosis-related fractures; the associated factors are understudied. We investigated incidence of bone fracture and its associations with soy food consumption, exercise, and body mass index among breast cancer survivors. Methods: This prospective study included 4139 stage 0-III breast cancer patients and 1987 pre-/perimenopausal and 2152 postmenopausal patients. Fractures were assessed at 18 months and at 3, 5, and 10 years after cancer diagnosis. Osteoporotic fractures were defined as fractures caused by falls from standing height and at sites associated with osteoporosis. Exercise and soy isoflavone intake were assessed at 6 and 18 months postdiagnosis. Weight and height were measured at baseline. Lifetable and Cox regression analyses were employed. All statistical tests were two sided. Results: The 10-year incidence for osteoporotic fractures was 2.9% and 4.4% for pre-/perimenopausal and postmenopausal patients, respectively. High soy isoflavone intake was associated with reduced risk among pre-/perimenopausal patients (hazard ratio [HR] = 0.22, 95% confidence interval [CI] = 0.09 to 0.53, for soy isoflavone mg/d >= 56.06 vs <31.31; P-trend <.001) but not among postmenopausal patients (P-interaction <.01). Overweight (vs normal weight) was a risk factor for pre-/perimenopausal patients (HR = 1.81, 95% CI = 1.04 to 3.14) but not for postmenopausal patients (HR = 0.67, 95% CI = 0.43 to 1.03; P-interaction =.01). Exercise was inversely associated with osteoporotic fractures in postmenopausal patients (HR = 0.56, 95% CI = 0.33 to 0.97, for metabolic equivalents hours >= 12.6 vs <4.5) following a dose-response pattern (P-trend =.035), an association not modified by menopausal status. Conclusions: Our findings, especially the novel association of soy food intake with osteoporotic fractures in breast cancer survivors, if confirmed, can help guide future strategies for fracture risk reduction in this vulnerable population.",
        "keywords": "",
        "authors": [
            {
                "name": "Neil Zheng",
                "org": "Yale Univ, Yale Coll, New Haven, CT USA"
            },
            {
                "name": "Evelyn Hsieh",
                "org": "Yale Univ, Yale Sch Med, Sect Rheumatol, New Haven, CT USA"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Dept Med, Div Epidemiol,Med Ctr, Nashville, TN USA"
            },
            {
                "name": "Liang Shi",
                "org": "Shanghai Municipal Ctr Dis Prevent & Control, Shanghai, Peoples R China"
            },
            {
                "name": "Kai Gu",
                "org": "Shanghai Municipal Ctr Dis Prevent & Control, Shanghai, Peoples R China"
            },
            {
                "name": "Ying Zheng",
                "org": "Shanghai Municipal Ctr Dis Prevent & Control, Shanghai, Peoples R China"
            },
            {
                "name": "Ping-Ping Bao",
                "org": "Shanghai Municipal Ctr Dis Prevent & Control, Shanghai, Peoples R China"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Dept Med, Div Epidemiol,Med Ctr, Nashville, TN USA"
            }
        ],
        "venue": "JNCI CANCER SPECTRUM",
        "year": 2019
    },
    "wrI5RoW6": {
        "id": "wrI5RoW6",
        "title": "Association of obesity-related genetic variants with endometrial cancer risk: A report from the shanghai endometrial cancer genetics study",
        "abstract": "Obesity is a well-established risk factor for endometrial cancer, the most common gynecologic malignancy. Recent genome-wide association studies (GWAS) have identified multiple genetic markers for obesity. The authors evaluated the association of obesity-related single nucleotide polymorphisms (SNPs) with endometrial cancer using GWAS data from their recently completed study, the Shanghai Endometrial Cancer Genetics Study, which comprised 832 endometrial cancer cases and 2,049 controls (1996-2005). Thirty-five SNPs previously associated with obesity or body mass index (BMI; weight (kg)/height (m)(2)) at a minimum significance level of < 5 x 10(-7) in the US National Human Genome Research Institute's GWAS catalog (\"http://genome.gov/gwastudies\" ) and representing 26 unique loci were evaluated by either direct genotyping or imputation. The authors found that for 22 of the 26 unique loci tested (84.6%), the BMI-associated risk variants were present at a higher frequency in cases than in population controls (P = 0.0003). Multiple regression analysis showed that 9 of 35 BMI-associated variants, representing 7 loci, were significantly associated (P < 0.05) with the risk of endometrial cancer; for all but 1 SNP, the direction of association was consistent with that found for BMI. For consistent SNPs, the allelic odds ratios ranged from 1.15 to 1.29. These 7 loci are in the SEC16B/RASAL, TMEM18, MSRA, SOX6, MTCH2, FTO, and MC4R genes. The associations persisted after adjustment for BMI, suggesting that genetic markers of obesity provide value in addition to BMI in predicting endometrial cancer risk.",
        "keywords": [
            "body mass index",
            "endometrial neoplasms",
            "genetics",
            "genome-wide association study",
            "obesity",
            "risk factors"
        ],
        "authors": [
            {
                "name": "Ryan J. Delahanty",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Alicia Beeghly-Fadiel",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Jiao Tong Univ, Dept Epidemiol, Shanghai Canc Inst, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Jirong Long",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Qiuyin Cai",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Wanqing Wen",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Wang-Hong Xu",
                "org": "Shanghai Jiao Tong Univ, Dept Epidemiol, Shanghai Canc Inst, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Jing He",
                "org": "Vanderbilt Univ, Sch Med, Dept Biostat, Nashville, TN 37212 USA"
            },
            {
                "name": "Yu Tang Gao",
                "org": "Shanghai Jiao Tong Univ, Dept Epidemiol, Shanghai Canc Inst, Shanghai 200030, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            },
            {
                "name": "Xiao Ou Shu",
                "org": "Vanderbilt Epidemiol Ctr, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF EPIDEMIOLOGY",
        "year": 2011
    },
    "rxLLAQlS": {
        "id": "rxLLAQlS",
        "title": "Prospective cohort study of tea consumption and risk of digestive system cancers: results from the Shanghai Women's Health Study.",
        "abstract": "Background: Data from in vitro and animal studies support a protective role for tea in the etiology of digestive system cancers; however, results from prospective cohort studies have been inconsistent. In addition, to our knowledge, no study has investigated the association of tea consumption with the incidence of all digestive system cancers in Chinese women. Objective: We investigated the association of regular tea intake (>= 3 times/wk for > 6 mo) with risk of digestive system cancers. Design: We used the Shanghai Women's Health Study, a population-based prospective cohort study of middle-aged and older Chinese women who were recruited in 1996-2000. Adjusted HRs and associated 95% CIs were derived from Cox regression models. Results: After a mean follow-up of 11 y, 1255 digestive system cancers occurred (stomach, esophagus, colorectal, liver, pancreas, and gallbladder/bile duct cancers) in 69,310 nonsmoking and non-alcohol-drinking women. In comparison with women who never drank tea, regular tea intake (mostly green tea) was associated with reduced risk of all digestive system cancers combined (HR: 0.86; 95% CI: 0.74, 0.98), and the reduction in risk increased as the amount and years of tea consumption increased (P-trend = 0.01 and P-trend < 0.01, respectively). For example, women who consumed >= 150 g tea/mo (similar to 2-3 cups/d) had a 21% reduced risk of digestive system cancers combined (HR: 0.79; 95% CI: 0.63, 0.99). The inverse association was found primarily for colorectal and stomach/esophageal cancers. Conclusion: In this large prospective cohort study, tea consumption was associated with reduced risk of colorectal and stomach/esophageal cancers in Chinese women. Am J Clin Nutr 2012;96:1056-63.",
        "keywords": [
            "china",
            "prospective studies",
            "incidence",
            "cohort studies",
            "tea",
            "proportional hazards models"
        ],
        "authors": [
            {
                "name": "Sarah Nechuta",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Xiao-Ou Shu",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Hong-Lan Li",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Gong Yang",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Bu-Tian Ji",
                "org": "NCI, Div Canc Epidemiol & Genet, Rockville, MD USA"
            },
            {
                "name": "Yong-Bing Xiang",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Hui Cai",
                "org": "Vanderbilt University School of Medicine(Vanderbilt University School of Medicine,Vanderbilt Univ. School of Medicine,Vanderbilt Univ. Sch. Med.),Nashville,United States"
            },
            {
                "name": "Wong-Ho Chow",
                "org": "NCI, Div Canc Epidemiol & Genet, Rockville, MD USA"
            },
            {
                "name": "Yu-Tang Gao",
                "org": "Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China"
            },
            {
                "name": "Wei Zheng",
                "org": "Vanderbilt Univ, Sch Med, Vanderbilt Epidemiol Ctr, Div Epidemiol,Dept Med, Nashville, TN 37203 USA"
            }
        ],
        "venue": "AMERICAN JOURNAL OF CLINICAL NUTRITION",
        "year": 2012
    },
    "ihm0WD7K": {
        "id": "ihm0WD7K",
        "title": "Research on a Novel Power Inverter Control Strategy Based on Micro-Grid",
        "abstract": "Based on summarizing a stand-alone running strategy of distributed power inverter and analyzing the possibility to control grid-connected power inverter with the same strategy, a novel micro-grid power inverter control method is proposed in this paper. While applying this method, the power inverter can not only output power in the grid- connected scenario, but also automatically produce power to satisfy the power demand or non-power demand about the load and power-sharing among inverters when the islanding and stand-alone events take place. It overcomes some traditional power inverter shortcoming that it can not make micro-grid smooth transition from grid-connected to islanding and to stand-alone status, due to the delay during different strategies being switched. At last, the effectiveness of the proposed method was proved by simulation results.",
        "keywords": [
            "Micro-grid",
            "Inverter",
            "Power control strategy"
        ],
        "authors": [
            {
                "name": "wei min chen",
                "org": "Jiliang Univ, Coll Elect & Automat China, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "wei wang",
                "org": "Jiliang Univ, Coll Elect & Automat China, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "hui cai",
                "org": "Jiliang Univ, Coll Elect & Automat China, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "guo cheng chen",
                "org": "Shanghai Univ, Coll Mechatron Engn & Automat, Shanghai, Peoples R China"
            }
        ],
        "venue": "MANUFACTURING SCIENCE AND TECHNOLOGY, PTS 1-8",
        "year": 2011
    },
    "LwTlXSmw": {
        "id": "LwTlXSmw",
        "title": "Special Feature: Grasslands of Inner MongoliaThe Grasslands of Inner Mongolia: A Special Feature",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xingguo Han",
                "org": ""
            },
            {
                "name": "Keith Owens",
                "org": ""
            },
            {
                "name": "X. Ben Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Jianhui Huang",
                "org": ""
            }
        ],
        "venue": "Rangeland Ecology & Management",
        "year": 2009
    },
    "30Ep0Rpg": {
        "id": "30Ep0Rpg",
        "title": "The Advances of the study on effects of climate change on the terrestrial biodiversity",
        "abstract": "The impacts of climate change on the biodiversity are become a crucial issue of conversation biodiversity.The general trends of the study impacts of climate change on the diversity of gene,population,and ecosystem diversity were reviewed and future research also been suggested in this paper.The studies about the effects of climate change on biodiversity should be further improved.",
        "keywords": [
            "biodiversity",
            "effects",
            "climate change"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "The Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Engineering Sciences",
        "year": 2008
    },
    "GTXRycxj": {
        "id": "GTXRycxj",
        "title": "Optimization Culture Conditions of DifferentiatingEndothelial Progenitor Cells From Human MononuclearCells in Vitro",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Department of Medical Oncology, China"
            },
            {
                "name": "Wang junjie",
                "org": "Department of Critical Care Medicine, China"
            },
            {
                "name": "Mao Anrong",
                "org": "Department of Liver Surgery, China"
            },
            {
                "name": "Wei Guo",
                "org": "Department of General Surgery, Shanghai, China"
            },
            {
                "name": "Zhou Hong",
                "org": "Department of hematology of Experimental Centre, China"
            },
            {
                "name": "Sun xingmin",
                "org": "Division of Infectious Diseases Cummings, USA"
            },
            {
                "name": "Xue Xuchao",
                "org": "Department of General Surgery, Shanghai, China"
            },
            {
                "name": "Bi Jianwei",
                "org": "Department of General Surgery, Shanghai, China"
            },
            {
                "name": "Fang guoen",
                "org": "Department of General Surgery, Shanghai, China"
            },
            {
                "name": "Xu Qing",
                "org": "Department of Medical Oncology, China"
            }
        ],
        "venue": "Biomedical Journal of Scientific and Technical Research",
        "year": 2019
    },
    "Oe6EpMXZ": {
        "id": "Oe6EpMXZ",
        "title": "Species richness and vegetation pattern in interdune lowlands of an active dune field in Inner Mongolia, China",
        "abstract": "Vegetation pattern in lowlands between active sand dunes has rarely been studied, but it may play an important role in maintaining the biodiversity This paper aims to quantify relationships between lowland area and species richness, composition and vegetation distribution and to provide suggestions on biodiversity conservation in the active dune field. Considering each interdune lowland as a self-contained unit, we investigated species composition and vegetation pattern in 25 interdune lowlands (ranging from 0.06 ha to 9.5 ha) of an active sand dune field. Our results showed that species richness increased with lowland area following a power function. The richness of psammophytes relative to the overall species richness decreased with lowland area logarithmically, but increase in lowland area did not lead to significant decrease in psammophyte's richness. With decrease of lowland area, frequency of psammophytes logarithmically increased, but that of nonpsammophytes logarithmically decreased. When the lowland area was about 2 ha, frequency of the psammophytes was equal to that of the nonpsammophytes (limnocryptophyte-meadow species and steppe species). Furthermore, a consistent pattern of vegetation differentiation along the direction of dune advancement occurred for lowlands larger than I ha: a psammophyte zone near the foot of leeward slope, a limnocryptophyte-meadow species zone in the central part of interdune lowland, and then followed by a psammophyte zone towards the foot of the windward slope. We concluded that lowland size is an important determinant of species diversity and vegetation pattern, and thus has implications for biodiversity conservation in sand dune fields. (C) 2007 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "biodiversity conservation",
            "limnocryptophyte species",
            "psammophyte",
            "semi-arid inner dunes",
            "steppe species",
            "species-area curve"
        ],
        "authors": [
            {
                "name": "Zhimin Liu",
                "org": ""
            },
            {
                "name": "Xiaolan Li",
                "org": "Institute of Applied Ecology, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, PR China"
            },
            {
                "name": "Qiaoling Yan",
                "org": "Institute of Applied Ecology, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute for Sustainability, Arizona State University, P.O. Box 874501, Tempe, AZ 85287-4501, USA"
            }
        ],
        "venue": "BIOLOGICAL CONSERVATION",
        "year": 2007
    },
    "9xMvIaUH": {
        "id": "9xMvIaUH",
        "title": "Inhibition of tumor growth and vasculogenic mimicry by cucumin through downregulation of the EphA2/PI3K/MMP pathway in a murine choroidal melanoma model",
        "abstract": "This study aims to investigate the underlying mechanism by which curcumin inhibits tumor growth and reduces vasculogenic mimicry (VM) in a murine choroidal melanoma model. Sixty mice were given subretinal injection with B16F10 cells and divided into a treatment and a control group. Curcumin was administered to the treatment group once a day at a dose of 100 mg/kg for 18 days starting at d3 (the day of inoculation is designated as d0); an equivalent volume of poloxamer-F68 was administered to the control group. Immunohistochemical and histochemical double staining were ued to detect the different blood supply patterns. The amounts of epithelial cell kinase (EphA2), phosphatidylinositol-3-kinase (PI3K) and matrixmetalloproteinase-2 and -9 (MMP-2, MMP-9) proteins expressed in the tumor tissue were analyzed using immunohistochemical staining; mRNA levels were measured using real-time PCR analysis. Results indicate that the tumor volume is reduced (p = 0.000) and that the numbers of VM (p = 0.000), mosaic vessels (p = 0.031) and endotheliumdependent vessels (p = 0.000) are significantly decreased by curcumin (p = 0.001). The expression levels of EphA2, PI3K, MMP-2 and -9 are also lower in the treatment group than in the control group (p = 0.001); similarly, mRNA levels in the treatment group are lower than those in the control group (p = 0.000). In conclusion, curcumin has the ability to inhibit the growth of engrafted melanoma VM channels through the regulation of vasculogenic factors that could be related to the downregulation of the EphA2/PI3K/MMPs signaling pathway. Thus, curcumin has the potential of being a clinical inhibitor of VM of choroidal melanoma. © 2011 Landes Bioscience.",
        "keywords": [
            "Choroidal melanoma",
            "Curcumin",
            "Endothelium-dependent vessels",
            "EphA2",
            "PI3K",
            "Tumor growth",
            "Vasculogenic mimicry"
        ],
        "authors": [
            {
                "name": "Lu-Xia Chen",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Yan-Jin He",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Shao-Zhen Zhao",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Jian-Tao Wang",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Li-Min Zhu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Ting-Ting Lin",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Bao-Cun Sun",
                "org": "Tianjin Cancer Institute and Hospital(Tianjin Cancer Hospital,Tianjin Cancer Institute),Tianjin,China"
            },
            {
                "name": "Xiao-Rong Li",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            }
        ],
        "venue": "Cancer Biology and Therapy",
        "year": 2011
    },
    "BljbNXVl": {
        "id": "BljbNXVl",
        "title": "Baseline characteristics of HCV-infected patients and healthy individuals.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Xuewu",
                "org": ""
            },
            {
                "name": "Zhu Chengliang",
                "org": ""
            },
            {
                "name": "Wang Tianci",
                "org": ""
            },
            {
                "name": "Jiang Hui",
                "org": ""
            },
            {
                "name": "Ren Yahui",
                "org": ""
            },
            {
                "name": "Zhang Qi",
                "org": ""
            },
            {
                "name": "Wu Kailang",
                "org": ""
            },
            {
                "name": "Liu Fang",
                "org": ""
            },
            {
                "name": "Liu Yingle",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2017
    },
    "TgK1C1kj": {
        "id": "TgK1C1kj",
        "title": "GP73 facilitates HCV infection and replication.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Xuewu",
                "org": ""
            },
            {
                "name": "Zhu Chengliang",
                "org": ""
            },
            {
                "name": "Wang Tianci",
                "org": ""
            },
            {
                "name": "Jiang Hui",
                "org": ""
            },
            {
                "name": "Ren Yahui",
                "org": ""
            },
            {
                "name": "Zhang Qi",
                "org": ""
            },
            {
                "name": "Wu Kailang",
                "org": ""
            },
            {
                "name": "Liu Fang",
                "org": ""
            },
            {
                "name": "Liu Yingle",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2017
    },
    "6EI1M0Dr": {
        "id": "6EI1M0Dr",
        "title": "Preliminary study on the extraction of Chitosan from mucor racemosus by UV mutagenesis and fermentation",
        "abstract": "In order to improve the production of chitosan,the influence of different fermenting and culture conditions on the extraction of chitosan from mucor racemosus was studied.Based on the researches on the UV mutagenesis of mucor racemosus and its fermentation conditions,the optimal fermenting conditions on the extraction of chitosan from mucor racemosus were set as the following:detesucrose(50 g/L),yeast extract(2.0 g/L),NaNO3(3.5 g/L),K2HPO4(1.0 g/L),MgSO4(0.2 g/L),FeSO4(0.2 g/L),fermenting temperature 30℃ and culture period 48 h.Under the above conditions,the extraction of chitosan can reach up to 1.12 g/L.",
        "keywords": [
            "fermentation",
            "chitosan",
            "mucor racemosus",
            "UV mutagenesis"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Yancheng College of Textile Technology,Yancheng,JiangSu,"
            },
            {
                "name": "WANG L",
                "org": "Yancheng College of Textile Technology,Yancheng,JiangSu,"
            }
        ],
        "venue": "Jiangsu Condiment and Subsidiary Food",
        "year": 2011
    },
    "Ah9ZoGiK": {
        "id": "Ah9ZoGiK",
        "title": "China's wetlands loss to urban expansion",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Dehua Mao",
                "org": "Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences Changchun 130102 PR China"
            },
            {
                "name": "Dehua Mao",
                "org": "Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences Changchun 130102 PR China"
            },
            {
                "name": "Zongming Wang",
                "org": "Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences Changchun 130102 PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University Tempe 85287 AZ USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University Tempe 85287 AZ USA"
            },
            {
                "name": "Bingfang Wu",
                "org": "Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences Beijing 100094 PR China"
            },
            {
                "name": "Yuan Zeng",
                "org": "Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences Beijing 100094 PR China"
            },
            {
                "name": "Kaishan Song",
                "org": "Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences Changchun 130102 PR China"
            },
            {
                "name": "Kunpeng Yi",
                "org": "Institute of Remote Sensing and Digital Earth Chinese Academy of Sciences Beijing 100094 PR China"
            },
            {
                "name": "Ling Luo",
                "org": "Key Laboratory of Wetland Ecology and Environment Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences Changchun 130102 PR China"
            }
        ],
        "venue": "Land Degradation & Development",
        "year": 2018
    },
    "a0niDea9": {
        "id": "a0niDea9",
        "title": "The X protein of HBV induces HIV-1 long terminal repeat transcription by enhancing the binding of C/EBPβ and CREB1/2 regulatory proteins to the long terminal repeat of HIV-1.",
        "abstract": "Due to share the route of transmission, the prevalence of co-infection of hepatitis B virus (HBV) and human immunodeficiency virus-1 (HIV-1) is high with chronic HBV infection affecting nearly 10% of HIV-infected patient world wide, which has become a significant global health problem. However, the cellular and molecular mechanisms associated with HBV/HIV-1 co-infection are largely unclear. In this study, we provided evidence that HBV induces HIV-1 transcription through its X protein (HBx). We further explored the mechanism by which HBx activates HIV-1 transcription. Our results showed that C/EBP and CRE cis-regulatory elements in the long terminal repeats (LTR) of HIV-1 are required for the activation of HIV-1 transcription mediated by HBx. We also demonstrated that HBx regulates HIV-1 transcription through stimulating the binding of transcriptional regulatory proteins C/EBPβ, CREB1, and CREB2 to HIV-1 LTR and that co-activator CBP is required for such regulation. These findings provide new insights into our understanding the effect of HBx on the activation of HIV-1 transcription and also provide evidence of the potential role of HBV in HIV-1 replication during the course of HBV/HIV-1 co-infection.",
        "keywords": [
            "hiv-1 long terminal repeats",
            "hbv/hiv-1 co-infection",
            "hepatitis b virus (hbv)",
            "human immunodeficiency virus-1 (hiv-1)",
            "transcription regulation",
            "molecular mechanics",
            "long terminal repeat",
            "global health"
        ],
        "authors": [
            {
                "name": "Yongxin Mu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yi Yu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Xin Yue",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ishaq Musarat",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Rui Gong",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Chengliang Zhu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, and Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Virus research",
        "year": 2011
    },
    "SJaR8sJX": {
        "id": "SJaR8sJX",
        "title": "Research on machine vision based networked supervisory control system",
        "abstract": "The hoop standard granulator is a key equipment in the feed industry. The performance of control system will directly affect the quality of feed particles and production efficiency. Conventional control strategy is to apply the PID control to achieve automatic control of the feeding volume and the amount of steam, but the quality of feed particles can not be guaranteed. In this paper, a control strategy of machine vision based networked supervisory control is proposed. Firstly, the feeding volume and the amount of steam is collected and controlled by the embedded technology. Secondly, a threshold segmentation algorithm based machine vision technology is used to detect the defects of feed particles. A machine vision based networked supervisory control mechanism is deployed through the RS-485 bus to adjusts the control effect and ensure high quality feed particles being produced. Simulation experiments were conducted on the independent software and hardware platform, and the results confirm the effectiveness of the proposed networked supervisory control.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaowei Yang",
                "org": "School of Electrical Engineering, Nantong University, Nantong, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Electrical Engineering, Nantong University, Nantong, China"
            },
            {
                "name": "Kun Zhang",
                "org": ""
            },
            {
                "name": "Peijian Zhang",
                "org": "School of Electronics and Information, Nantong University, Nantong, China"
            },
            {
                "name": "Conghua Xie",
                "org": "School of Computer Science and Engineering, Changshu Institute of Technology, Suzhou, China"
            }
        ],
        "venue": "ukacc international conference on control",
        "year": 2016
    },
    "bEZJoL6g": {
        "id": "bEZJoL6g",
        "title": "Epidemiological and Clinical Characteristics of COVID-19 Patients in Shiyan City of Hubei Province, China",
        "abstract": "Background: The outbreak of the 2019 novel coronavirus (2019-nCoV, also named SARS-CoV-2) has spread from Wuhan to outside of Hubei province and other countries or regions, caused thousands of patients with disease named “Coronavirus Disease 2019 (COVID-19)”, and led to a public health emergency of international concern (PHEIC) declared by World Health Organization (WHO). The person-to-person spread of SARS-CoV-2 was reported among close contacts.Methods: To investigate the early epidemic of COVID-19, totally 176 confirmed COVID-19 cases in Shiyan city, Hubei province, China were surveyed. Their traces of activities and contacts were tracked and analyzed. Among the 176 confirmed cases, 53 patients were admitted to the Shiyan Renmin Hospital of Hubei University of Medicine. The clinical characteristics on the 53 patients were collected and compared based on the nucleotides and pneumonia in laboratory inspection.Findings: The early confirmed COVID-19 cases in Hubei province outside Wuhan were emerged by migrate rate-dependent, and the second-generation patients were mainly cluster-onset between family members from Wuhan travelers. Epidemiological investigation indicated that 10.7% (12/112) of local COVID-19 cases were transferred SARS-CoV-2 by asymptomatic infected individuals. Clinical data showed that 47.2% (25/53) of the COVID-19 patients were co-infected with the Meningococcal pneumonia. Interpretation: It should be paid more attentions to the high incidence of coinfections with M. pneumoniae in the COVID-19 patients. It is necessary to assess the transmissibility of asymptomatic infected individuals and other possibilities for SARS-CoV-2 transmission. The strict intervention measures should be adopted by the public to lower basic reproduction number and stop the spread.Funding Statement: This work was supported by research grants from the National Natural Science Foundation of China (81902066, 81730061, and 81471942), the Natural Science Foundation of Hubei Provincial Department of Education (Q20192105 and Q20192104), the Hubei Provincial Natural Science Foundation (2018CFB185 and 2018CFB093), Cultivating Project for Young Scholar at Hubei University of Medicine (2017QDJZR08 and 2016QDJZR03), and National Undergraduate Training Program for Innovation and Entrepreneurship (201913249002). Declaration of Interests: The authors have no conflicts of interest to disclose.Ethics Approval Statement: This study was conducted in accordance with the Declaration of Helsinki. This study was approved by the Shiyan Renmin Hospital of Hubei University of Medicine institutional review board and the need for informed consent was waived.",
        "keywords": "",
        "authors": [
            {
                "name": "Long Liu",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Xu Lei",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Xiao Xiao",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Jing Yang",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Jian Li",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Manshan Ji",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Weixing Du",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Huabing Tan",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Jianyong Zhu",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Li Bei",
                "org": "Hubei University of Medicine - Department of Infectious Diseases"
            },
            {
                "name": "Zhixiong Jin",
                "org": "Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Clinical Laboratory"
            },
            {
                "name": "Weiyong Liu",
                "org": "Huazhong University of Science and Technology (Formerly Tongi Medical University) - Department of Clinical Laboratory"
            },
            {
                "name": "Jianguo Wu",
                "org": "Jinan University - Guangdong Provincial Key Laboratory of Virology; Wuhan University - State Key Laboratory of Virology"
            },
            {
                "name": "Zhixin Liu",
                "org": "Hubei University of Medicine - Department of Infectious Diseases; Wuhan University - State Key Laboratory of Virology"
            }
        ],
        "venue": "SSRN Electronic Journal",
        "year": 2020
    },
    "XZlimYPK": {
        "id": "XZlimYPK",
        "title": "Amur tigers and leopards returning to China: direct evidence and a landscape conservation plan",
        "abstract": "The Amur tiger and leopard, once roaming over the Eurasian continent, are now endangered and confined to the Sikhote-Alin Mountains, Russia—a landscape that has been increasingly fragmented due to human activities. The ultimate fate of these big cats depends on whether they can resettle in their previous main historical range in NE China. Recent sightings of these animals along the China–Russia border have aroused new hope, but direct evidence is lacking.",
        "keywords": [
            "Panthera tigris altaica",
            " Panthera pardus orientalis",
            " Camera-trapping",
            " Human disturbance",
            " Cattle control",
            " Nature reserve",
            " Conservation planning"
        ],
        "authors": [
            {
                "name": "tianming wang",
                "org": "beijing normal university"
            },
            {
                "name": "limin feng",
                "org": "beijing normal university"
            },
            {
                "name": "pu mou",
                "org": "beijing normal university"
            },
            {
                "name": "jianguo wu",
                "org": "beijing normal university"
            },
            {
                "name": "james l d smith",
                "org": "university of minnesota"
            },
            {
                "name": "wenhong xiao",
                "org": "beijing normal university"
            },
            {
                "name": "haitao yang",
                "org": "beijing normal university"
            },
            {
                "name": "hailong dou",
                "org": "beijing normal university"
            },
            {
                "name": "xiaodan zhao",
                "org": "beijing normal university"
            },
            {
                "name": "yanchao cheng",
                "org": "beijing normal university"
            },
            {
                "name": "bo zhou",
                "org": "beijing normal university"
            },
            {
                "name": "hongyan wu",
                "org": "beijing normal university"
            },
            {
                "name": "li zhang",
                "org": "beijing normal university"
            },
            {
                "name": "yu tian",
                "org": "State Key Laboratory of Environmental Criteria and Risk Assessment,Chinese Research Academy of Environmental Science,Beijing,China"
            },
            {
                "name": "qingxi guo",
                "org": "northeast forestry university"
            },
            {
                "name": "xiaojun kou",
                "org": "beijing normal university"
            },
            {
                "name": "xuemei han",
                "org": "natureserve"
            },
            {
                "name": "dale g miquelle",
                "org": "wildlife conservation society"
            },
            {
                "name": "c d oliver",
                "org": "yale university"
            },
            {
                "name": "rumei xu",
                "org": "beijing normal university"
            },
            {
                "name": "jianping ge",
                "org": "beijing normal university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "AjhViKPu": {
        "id": "AjhViKPu",
        "title": "Linking stoichiometric homeostasis with ecosystem structure, functioning, and stability",
        "abstract": "",
        "keywords": [
            "ecology"
        ],
        "authors": [
            {
                "name": "qiang yu",
                "org": ""
            },
            {
                "name": "quansheng chen",
                "org": ""
            },
            {
                "name": "j elser",
                "org": ""
            },
            {
                "name": "arianne j cease",
                "org": ""
            },
            {
                "name": "nianpeng he",
                "org": ""
            },
            {
                "name": "honghui wu",
                "org": ""
            },
            {
                "name": "guangming zhang",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "yongfei bai",
                "org": ""
            },
            {
                "name": "xingguo han",
                "org": ""
            }
        ],
        "venue": "Nature Precedings",
        "year": 2010
    },
    "hLZvtqIm": {
        "id": "hLZvtqIm",
        "title": "HPLC Fingerprints of Erzhi Pill Extract",
        "abstract": "Objective To establish HPLC fingerprint of Erzhi pill extract.Methods The fingerprints of Erzhi pill and its single herb extract were compared by HPLC-DAD method.The separation was performed on Kromasil C 18(4.6×250 mm,5μm) with gradient elution of acetonitrile-0.2% phosphoric acid solution as mobile phase,column temperature was 30℃,flow rate was 1.0 mL.min-1,and the detective wavelength was 340 nm.Results There were 33 chromatographic peaks in the fingerprints of Erzhi pill and its single herb extract,six of them came from ligustrum lucidum ait.extract,twenty eight of them came from herba ecliptae extract,and one common peak appeared at 14 min.Conclusion The HPLC fingerprint of Erzhi pill extract established by HPLC-DAD method could objectively reflect the chemical composition of Erzhi pill and its single herb,and provide experimental basis for the quality standard of Erzhi pill preparation.",
        "keywords": [
            "HPLC",
            "fingerprint",
            "Erzhi pill"
        ],
        "authors": [
            {
                "name": "WU Yanbin",
                "org": "Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian ,China"
            },
            {
                "name": "LIN Xionghao",
                "org": "Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian ,China"
            }
        ],
        "venue": "Journal of Fujian University of Traditional Chinese Medicine",
        "year": 2012
    },
    "FNeuAkRG": {
        "id": "FNeuAkRG",
        "title": "Human endogenous retroviral pol RNA and protein detected and identified in the blood of individuals with schizophrenia.",
        "abstract": "Retrovirus has been speculated as one of the potential infectious agents involved in the development of schizophrenia. Here we used nested RT-PCR to detect the RNA of HERV pol gene in blood from schizophrenic patients and normal human. We found retroviral pol genes expressed in blood from 20 of 58 (34.5%) individuals with recent-onset schizophrenia, but not from 38 normal persons (p<0.01). Sequence analysis revealed that the expressed gene was homologous to those of the human endogenous retroviral (HERV) family. The ERV9 family was the closest, with 90% homology in the gene sequence. In addition, Western blots showed that antibody against ERV9 pol protein in serum from the HERV+ schizophrenia patients, but not from control (p<0.01). Our data suggested that the transcriptional activation of certain retroviral elements might be associated with the development of schizophrenia in some patients. Further characterization of retroviral elements in subjects with schizophrenia may aid in better diagnosis and treatment of this disorder.",
        "keywords": [
            "herv",
            "pol",
            "schizophrenia"
        ],
        "authors": [
            {
                "name": "Wen-Jie Huang",
                "org": ""
            },
            {
                "name": "Zhong-Chun Liu",
                "org": ""
            },
            {
                "name": "Wei Wei",
                "org": "College of Life Sciences, Wuhan University, Wuhan 430072, People's Republic of China"
            },
            {
                "name": "Gao-Hua Wang",
                "org": "Ren-Ming Hospital, Wuhan University, Wuhan 430060, People's Republic of China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Fan Zhu",
                "org": ""
            }
        ],
        "venue": "Schizophrenia research",
        "year": 2006
    },
    "zVhlSwq6": {
        "id": "zVhlSwq6",
        "title": "Relationships between Kobresia's species richness and climatic factors in China]",
        "abstract": "Based on the information from collected literatures, this paper defined the geographical distribution of Kobresia in China, and analyzed the relationships between the Kobresia's species richness and climatic factors. The Kobresia in China had higher species richness on the borders of Yunnan Province, Sichuan Province, and Tibet Autonomous Region and in the southeast Qinghai Province and Himalayas, with a denser and wider distribution in the areas of < 40 degrees N, 85 degrees-105 degrees E and > altitude 2500 m, or the areas of lower or medium thermal factors, medium precipitation, medium aridity and humidity, or medium sunshine duration. The species richness was significantly negatively correlated with the mean, maximum, and minimum air temperature in July and the mean air temperature in summer (P < 0.05), and well corresponded to the isolines of warmth index, annual biotemperature, extreme maximum air temperature, air temperature in summer, and mean, maximum, and minimum air temperature in July. Multiple linear regression analysis indicated that the maximum air temperature in July and the precipitation in spring had significant effects on the species richness (P<0.05) , with the greatest contribution of the maximum air temperature in July. Stepwise regression analysis indicated that the mean air temperature in July and the mean annual maximum and extreme maximum air temperature had significant effects on the species richness (P < 0.05), and the principal component regression analysis indicated that the extreme maximum air temperature, air temperature in July and summer, Thornthwaite aridity index, sunshine hours in April-October, precipitation in summer and autumn, and annual precipitation had greater effects on the richness. The air temperature, precipitation, and sunshine hours in growth season as well as the extreme maximum air temperature, annual precipitation, and soil moisture content were the main factors affecting the geographical distribution of Kobresia in China.",
        "keywords": [
            "Climatic factor",
            "Kobresia plant",
            "Richness"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "Qiao-Fu Zhou",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban",
        "year": 2012
    },
    "AbkDlGK2": {
        "id": "AbkDlGK2",
        "title": "Developmental genetic analysis of brown rice thickness of indica rice (Oryza sativa L.)",
        "abstract": "Analysis of developmental genetic effects for brown rice thickness (BRT) trait in indica rice (Oryza sativa L.) at four different filling stages was conducted and a developmental genetic model and corresponding statistical approaches for quantitative traits of triploid endosperm in cereal crops was used. The results indicated that the diploid maternal plant, triploid endosperm and cytoplasmic genetic effects were important for BRT trait at all filling stages of rice and those effects were the major effect at initial medium, filling period and mature period respectively. The additive and dominance effects were the major effect alternatively at four filling stages of rice. Significant endosperm and maternal dominance effects for BRT suggest that the utilization of heterosis for BRT is viable. The results of conditional genetic variance components shown that the expression of new quantitative genes in endosperm, cytoplasm and maternal plant for BRT was found at most filling stages of rice. The gene expression was most active at the early filling stages, especially at the second stage (8-∼ 14 days after flowering). Near to mature period (22∼ 28 days after flowering), however, the expression of genes decreased sharply and even closed. The phenomena that the genes expressed spasmodically, i.e. the net genetic effects equaled to zero in some filling stages were detected for some genetic effects. Dominance and cytoplasmic correlation coefficients were significant at 0.05 or 0.01 probability level in some filling stages meanwhile there were the most strong relationship between mature period and other periods for BRT.",
        "keywords": [
            "Brown rice thickness",
            "Developmental genetics",
            "Genetic correlations",
            "Genetic variances and conditional genetic variances",
            "Indica rice (Oryza sativa L.)"
        ],
        "authors": [
            {
                "name": "LongJiang Fan",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jun Zhu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ping Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Yi chuan xue bao = Acta genetica Sinica",
        "year": 2000
    },
    "QDH21mPp": {
        "id": "QDH21mPp",
        "title": "Toll-like receptor 3-activated macrophages confer anti-HCV activity to hepatocytes through exosomes.",
        "abstract": "Exosomes are a class of cell-released small vesicles that mediate intercellular communication by delivering functional factors to recipient cells. During hepatitis C virus (HCV) infection, the interaction between liver resident macrophages and hepatocytes is a key component in liver innate immunity. In this study, we explored the role of exosomes in the delivery of innate anti-HCV factors to hepatocytes from macrophages. We showed that supernatant from TLR3-activated macrophage cultures could efficiently inhibit HCV replication in Huh7 cells. This macrophage-mediated anti-HCV activity was through exosomes because inhibiting exosomes could abrogate the action of macrophages. Further analyses demonstrated that TLR3-activated macrophages release exosomes that contain anti-HCV microRNA (miRNA)-29 family members. Inhibiting miRNA29 could restore HCV replication. These findings suggest a novel antiviral mechanism in liver innate immunity against HCV infection and provide insights to support further studies on developing exosome-based delivery system for disease treatment.-Zhou, Y., Wang, X., Sun, L., Zhou, L., Ma, T.-C., Song, L., Wu, J.-G., Li, J.-L., Ho, W.-Z. Toll-like receptor 3-activated macrophages confer anti-HCV activity to hepatocytes through exosomes.",
        "keywords": [
            "exosomes",
            "hepatitis C virus",
            "miRNA"
        ],
        "authors": [
            {
                "name": "Yu Zhou",
                "org": "Department of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA; and yu.zhou@temple.edu."
            },
            {
                "name": "Xu Wang",
                "org": ""
            },
            {
                "name": "Li Sun",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Li Zhou",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Tong-Cui Ma",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Li Song",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jian-Guo Wu",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jie-Liang Li",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wen-Zhe Ho",
                "org": "The State Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, China."
            }
        ],
        "venue": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
        "year": 2016
    },
    "C3kvckGC": {
        "id": "C3kvckGC",
        "title": "Shear buckling analysis on plate panel",
        "abstract": "The elastic buckling of three simply supported edges plate under shear load is analyzed by energy method,and the calculation formula for critical buckling stress of three simply supported edges plate has been deduced.Numerical calculation has been carried out by FEA on the elastic buckling of three simply supported edges plate under uniform shear.It shows that the critical stress calculation formula matches the numerical results by FEA well when slenderness ratio is larger than 1.5.",
        "keywords": [
            "energy method",
            "elastic shear critical stress",
            "FEA",
            "three simply supported edges"
        ],
        "authors": [
            {
                "name": "WANG Jian-zhong",
                "org": "China United Engineering Corporation,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Civil Engieering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "SHAN Lu-yang",
                "org": "College of Civil Engieering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "HONG Ying",
                "org": "China Classification Society Shanghai Institute,Shanghai ,China"
            }
        ],
        "venue": "Ship & Boat",
        "year": 2012
    },
    "YM0aUi6b": {
        "id": "YM0aUi6b",
        "title": "Study on Method of Improving Efficiency of Software Testing",
        "abstract": "Software testing is indispensable to the development of software,and is the key to software quality.Expounds the defect and problems in software testing from the purpose that improving the efficiency of the software testing.Analyze and study the method of improving efficiency of the software testing,then give an integrated software testing flow.",
        "keywords": [
            "software testing",
            "software quality",
            "efficiency of software testing"
        ],
        "authors": [
            {
                "name": "FAN Qing-lin",
                "org": "College of Computer Science & Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Computer Science & Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2006
    },
    "olYlQ1tu": {
        "id": "olYlQ1tu",
        "title": "Developmental Genetic Analysis of Brown Rice Weight Under Different Environmental Conditions in indica Rice",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shi Chun-Hai",
                "org": ""
            },
            {
                "name": "Wu Jian-Guo",
                "org": ""
            },
            {
                "name": "Fan Long-Jiang",
                "org": ""
            },
            {
                "name": "Zhu Jun",
                "org": ""
            },
            {
                "name": "Wu Ping",
                "org": ""
            }
        ],
        "venue": "Journal of Integrative Plant Biology",
        "year": 2001
    },
    "B9hSM3U3": {
        "id": "B9hSM3U3",
        "title": "Decoupling species richness variation and spatial turnover in beta diversity across a fragmented landscape.",
        "abstract": "These results highlight the importance of hierarchical linkages between components of biodiversity across scales in fragmented landscapes, and have practical conservation implications.",
        "keywords": [
            "Area effect",
            "Environmental filtering",
            "Isolation",
            "Land-bridge islands",
            "Plant functional type",
            "Thousand Island Lake"
        ],
        "authors": [
            {
                "name": "Guang Hu",
                "org": "School of Civil Engineering and Architecture, Zhejiang Sci-Tech University, Hangzhou, China."
            },
            {
                "name": "Maxwell C Wilson",
                "org": "School of Life Sciences, Arizona State University, Tempe, AZ, USA."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ, USA."
            },
            {
                "name": "Jingjing Yu",
                "org": "College of Life Sciences, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Mingjian Yu",
                "org": "College of Life Sciences, Zhejiang University, Hangzhou, China."
            }
        ],
        "venue": "PeerJ",
        "year": 2019
    },
    "T2eWz7q9": {
        "id": "T2eWz7q9",
        "title": "Diagnosis and treatment of lumbar hernia:a report of 9 cases",
        "abstract": "Objective To study the pathogeny,clinical manifestlation,diagnosis and treatment of lumbar hernia.Methods The clinical data of 9 cases of lumber hernia admitted from January 1997 to January 2007 in the Department of General Surgery Affiliated Changhai Hospital of the Second Military Medical University were analyzed retrospectively.Results Among 9 cases,1 case was caused by nature.Two cases were caused by traumatic factors and 6 cases were caused by other factors.The clinical manifestation of lumbar hernia included lumbar bump in 9 cases,lumbar pain in 5 cases,nausea and vomiting in 2 cases,gut incarcerated with bowel obstruction in 1 case.The typical sign was a painful flank bulging in the superior or inferior triangle.Seven cases had hernia in superior lumbar triangle;one of them had hernia in both inferior lumbar triangle and superior lumbar triangle.Hernioplasty included by using contiguity tissue and synthetic patch were performed in 8 of all the cases.Conclusion The diagnosis could be made according to clinical symptoms and signs.Doppler ultrasound examination,CT and MRI scanning are helpful for diagnosing lumbar hernia.Excision of the sac and repairing with surrounding tissue or by prosthetic material may show satisfactory results.",
        "keywords": [
            "lumber hernia",
            "lumbar triangle"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": ".Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "FANG Guo-en",
                "org": ".Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "LUO Tian-hang",
                "org": ".Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Surgery",
        "year": 2008
    },
    "758Kx7wr": {
        "id": "758Kx7wr",
        "title": "Activation of the Ras/Raf/MEK pathway facilitates hepatitis C virus replication via attenuation of the interferon-JAK-STAT pathway.",
        "abstract": "Hepatitis C virus (HCV) is a major cause of chronic liver diseases worldwide, often leading to the development of hepatocellular carcinoma (HCC). Constitutive activation of the Ras/Raf/MEK pathway is responsible for approximately 30% of cancers. Here we attempted to address the correlation between activation of this pathway and HCV replication. We showed that knockdown of Raf1 inhibits HCV replication, while activation of the Ras/Raf/MEK pathway by V12, a constitutively active form of Ras, stimulates HCV replication. We further demonstrated that this effect is regulated through attenuation of the interferon (IFN)-JAK-STAT pathway. Activation of the Ras/Raf/MEK pathway downregulates the expression of IFN-stimulated genes (ISGs), attenuates the phosphorylation of STAT1/2, and inhibits the expression of interferon (alpha, beta, and omega) receptors 1 and 2 (IFNAR1/2). Furthermore, we observed that HCV infection activates the Ras/Raf/MEK pathway. Thus, we propose that during HCV infection, the Ras/Raf/MEK pathway is activated, which in turn attenuates the IFN-JAK-STAT pathway, resulting in stimulation of HCV replication.",
        "keywords": [],
        "authors": [
            {
                "name": "Qi Zhang",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Rui Gong",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Jing Qu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Yijing Zhou",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Mingzhou Chen",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital(Chinese-French Liver Disease Research Institute at Zhongnan Hospital),Wuhan,China"
            }
        ],
        "venue": "Journal of virology",
        "year": 2012
    },
    "OaBeNgcr": {
        "id": "OaBeNgcr",
        "title": "The gSpan Algorithm Based on Compound-Library Testing",
        "abstract": "Introduces a graph-based substructure pattern mining algorithm called gSpan,which discovers frequent substructures without candidate generation and adopts the depth-first search strategy to mine frequent connected subgraphs efficiently.Its performance is enhanced because the continuous design and non-candidate.When it is applied on the chemical compound-library Chemical-340,gSpan substantially outperforms previous algorithms such as FSG, sometimes by an order of magnitude.gSpan can be applied in the research of finding compounds with same substructure,it is very important to related areas.",
        "keywords": [
            "DFS",
            "compound-library",
            "frequent subgraphs",
            "gSpan"
        ],
        "authors": [
            {
                "name": "XU Rong-bin",
                "org": "Ministry of Education Key Laboratory of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "XIE Ying",
                "org": "Ministry of Education Key Laboratory of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Ministry of Education Key Laboratory of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2007
    },
    "Z0R2yeVu": {
        "id": "Z0R2yeVu",
        "title": "Evaluation of the 3D finite element method using a tantalum rod for osteonecrosis of the femoral head.",
        "abstract": "The aim of this study was to contrast the collapse values of the postoperative weight-bearing areas of different tantalum rod implant positions, fibula implantation, and core decompression model and to investigate the advantages and disadvantages of tantalum rod implantation in different ranges of osteonecrosis in comparison with other methods.The 3D finite element method was used to establish the 3D finite element model of normal upper femur, 3D finite element model after tantalum rod implantation into different positions of the upper femur in different osteonecrosis ranges, and other 3D finite element models for simulating fibula implant and core decompression.The collapse values in the weight-bearing area of the femoral head of the tantalum rod implant model inside the osteonecrosis area, implant model in the middle of the osteonecrosis area, fibula implant model, and shortening implant model exhibited no statistically significant differences (p&amp;gt;0.05) when the osteonecrosis range was small (60°). The stress values on the artificial bone surface for the tantalum rod implant model inside the osteonecrosis area and the shortening implant model exhibited statistical significance (p&amp;lt;0.01).Tantalum rod implantation into the osteonecrosis area can reduce the collapse values in the weight-bearing area when osteonecrosis of the femoral head (ONFH) was in a certain range, thereby obtaining better clinical effects. When ONFH was in a large range (120°), the tantalum rod implantation inside the osteonecrosis area, shortening implant or fibula implant can reduce the collapse values of the femoral head, as assessed by other methods.",
        "keywords": [
            "mechanical",
            "stress",
            "finite element analysis"
        ],
        "authors": [
            {
                "name": "Jingsheng Shi",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Jie Chen",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Feiyan Chen",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Guangyong Huang",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Zhan Wang",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Guanglei Zhao",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Yibing Wei",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            },
            {
                "name": "Siqun Wang",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, China (mainland)."
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2014
    },
    "fQ6JKsmo": {
        "id": "fQ6JKsmo",
        "title": "Major histocompatibility complex-peptide tetramer technique and its application for antigen specific T cell quantitative determination",
        "abstract": "Tetramer technique is a newly developed method for antigen specific T cell(AST) determination,and has a extensive application foreground in virus infection,tumor and autoimmunone disease investigation,also in immuno-dominant epitope of antigen-peptide option.This paper briefly presents the molecular bases of major histocompatibility complex(MHC)-antigen peptide and T cell receptor(TCR) interaction,tetramer development and technique types of tetramer,also summarizes actuality of this technique in AST application for clinical research.",
        "keywords": [
            "Tetramer",
            "Antigen-peptide",
            "Major histocompatibility complex",
            "Antigen specific T cells"
        ],
        "authors": [
            {
                "name": "YU Wei",
                "org": "Department of Center Laboratory,Institute of Medical Laboratory Science of PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Xiao-jun",
                "org": "Department of Center Laboratory,Institute of Medical Laboratory Science of PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Department of Center Laboratory,Institute of Medical Laboratory Science of PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2008
    },
    "hb2zI7iu": {
        "id": "hb2zI7iu",
        "title": "Traffic signal monitoring system of mine slope based on spread-spectrum communications",
        "abstract": "For the purpose of proper working in highly disturbed environment of underground mining,advantages of spread-spectrum communications and anti-jamming principle of spread-spectrum were analyzed.The working principle and system structure of the DS/SS were also investigated.Usage of synchronization in the DS/SS was focused.The spread-spectrum communications was applied for the traffic signal monitoring system of mine slope.Result indicates that adopting the spread-spectrum communications can solve such problems as low security and veracity.The developed system with independent standard has gotten the practical application,filled up the blank in the monitoring of the safe transportation of mine slope,and increased the reliability of information management of the mine.The application and technology performance of this system have reached the leading level in China.",
        "keywords": [
            "direct sequence spread spectrum",
            "anti-jamming",
            "slope",
            "synchronization",
            "spread-spectrum communications",
            "monitoring system of mine"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "XIE Ying",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "XU Rong-bin",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Journal of Shenyang University of Technology",
        "year": 2007
    },
    "xgyRN3uS": {
        "id": "xgyRN3uS",
        "title": "Suppression of Jasmonic Acid-Mediated Defense by Viral-Inducible MicroRNA319 Facilitates Virus Infection in Rice.",
        "abstract": "MicroRNAs (miRNAs) are pivotal modulators of plant development and host-virus interactions. However, the roles and action modes of specific miRNAs involved in viral infection and host susceptibility remain largely unclear. In this study, we show that Rice ragged stunt virus (RRSV) infection caused increased accumulation of miR319 but decreased expression of miR319-regulated TCP (TEOSINTE BRANCHED/CYCLOIDEA/PCF) genes, especially TCP21, in rice plants. Transgenic rice plants overexpressing miR319 or downregulating TCP21 exhibited disease-like phenotypes and showed significantly higher susceptibility to RRSV in comparison with the wild-type plants. In contrast, only mild disease symptoms were observed in RRSV-infected lines overexpressing TCP21 and especially in the transgenic plants overexpressing miR319-resistant TCP21. Both RRSV infection and overexpression of miR319 caused the decreased endogenous jasmonic acid (JA) levels along with downregulated expression of JA biosynthesis and signaling-related genes in rice. However, treatment of rice plants with methyl jasmonate alleviated disease symptoms caused by RRSV and reduced virus accumulation. Taken together, our results suggest that the induction of miR319 by RRSV infection in rice suppresses JA-mediated defense to facilitate virus infection and symptom development. ",
        "keywords": [
            "RRSV",
            "TCP21",
            "jasmonic acid",
            "miR319",
            "rice ragged stunt virus",
            "viral infection"
        ],
        "authors": [
            {
                "name": "Chao Zhang",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Zuomei Ding",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Kangcheng Wu",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Liang Yang",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Yang Li",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Zhen Yang",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Shan Shi",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Xiaojuan Liu",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Shanshan Zhao",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Zhirui Yang",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Yu Wang",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Luping Zheng",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Juan Wei",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Zhenguo Du",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China."
            },
            {
                "name": "Aihong Zhang",
                "org": "Plant Protection Institute, Hebei Academy of Agriculture and Forestry Sciences, Baoding 071000, China."
            },
            {
                "name": "Hongqin Miao",
                "org": "Plant Protection Institute, Hebei Academy of Agriculture and Forestry Sciences, Baoding 071000, China."
            },
            {
                "name": "Yi Li",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Zujian Wu",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China. Electronic address: wuzujian@126.com."
            },
            {
                "name": "Jianguo Wu",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China; The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing 100871, China. Electronic address: wujianguo81@126.com."
            }
        ],
        "venue": "Molecular plant",
        "year": 2016
    },
    "c3ZikX55": {
        "id": "c3ZikX55",
        "title": "Assessing environmental inequalities in the city of Santiago (Chile) with a hierarchical multiscale approach",
        "abstract": "Abstract   Environmental inequalities are a common characteristic of urban areas. Environmental inequality is the unequal spatial distribution of environmental risks and goods among social groups. As environmental inequalities are inherently a spatial matter the choice of scale is essential for correctly understanding inequality issues and for designing proper and effective mitigation policies. However, the potential effects of scale of analysis on inequalities results have largely been underestimated in the assessment of environmental inequalities, leading to contradictory results from different studies. In this study we assess the patterns of environmental inequalities and associated scale issues in the city of Santiago (Chile) using a hierarchical multiscale approach. Our approach focuses on the analysis of spatial relationships between three environmental (i.e., surface temperature, air pollution, vegetation cover) and two socio-demographic variables (i.e., household wealth, population density) on multiple grain sizes and extents. We used census data, remote sensing data, and air pollution monitoring stations to generate raster layers at five grain sizes and five nested extents. We tested for inequalities through Pearson correlation analysis resulting in a total of 1530 assessed relationships. Our results show that environmental inequalities are a prevalent phenomenon in the city of Santiago, but the details of these inequalities are highly scale dependent. Changing the grain size and extent of analysis do not only affect the strength of relationships between socio-demographic and environmental variables, but also the spatial distribution of environmental inequalities across the urban landscape. Therefore, due to the scale-dependence of assessment results, researchers and decision-makers should be extremely careful when interpreting their findings and translating them into policy making. If the scale dependency of environmental inequalities is not taken into account, policy interventions may be largely ineffective because the scale at which interventions are designed may not match the scale at which inequalities are generated.",
        "keywords": "",
        "authors": [
            {
                "name": "Ignacio C. Fernández",
                "org": "School of Sustainability, Arizona State University, P.O. Box 874501, Tempe, AZ 85287-4501, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Sustainability, Arizona State University, P.O. Box 874501, Tempe, AZ 85287-4501, USA"
            }
        ],
        "venue": "Applied Geography",
        "year": 2016
    },
    "u062W89a": {
        "id": "u062W89a",
        "title": "Selective Cytolysis of Tumor Cells by Mumps Virus S<sub>79</sub>",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Yin-Fang Yan",
                "org": ""
            },
            {
                "name": "Xiao Chen",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Chang-Yuan Dong",
                "org": ""
            }
        ],
        "venue": "Intervirology",
        "year": 2005
    },
    "oCKYg35x": {
        "id": "oCKYg35x",
        "title": "Analysis of the conditional correlations from different genetic systems between the protein content and the appearance quality traits of indica rice.",
        "abstract": "A factorial mating design in two environments was conducted using 7 cytoplasmic male sterile lines (A) and 5 restorer lines (R) along with their F1 (A × R) and F2 populations. The unconditional and conditional analyses of genetic models and the cor- responding statistic methods, including endospermic, cytoplasmic, and maternal plant genetic systems, were used to analyze the genetic relationships between protein content (PC) and the appearance quality traits of indica rice (Oryza sativa L.). The results from unconditional analysis indicated that PC was significantly correlated with the appearance quality traits of rice, except for the brown rice thickness (BRT). Only the genetic covariance between PC and the brown rice width (BRW) was positively correlative, whereas all the other pairwise traits were negatively correlative. The results from conditional analysis revealed that the weight of brown rice (WBR) or the amylose content (AC) could significantly affect the relationships between PC and the appearance quality traits of indica rice. The conditional analysis showed that WBR might negatively affect the relationships between PC and the brown rice length (BRL), BRW, or BRT through the genotype × environmental (GE) interaction effects, but positively affected the rela- tionships between PC and the ratio of brown rice length to width (RLW) or the ratio of brown rice length to thickness (RLT). The amylase content could positively affect the relationships between PC and BRL, RLW, RLT through the cytoplasmic effects and ma- ternal additive effects, but negatively affected the relationships between PC and BRW.",
        "keywords": [
            "protein content",
            "amylose content",
            "appearance quality",
            "covariance",
            "indica rice ( oryza sativa l.)",
            "unconditional and conditional analysis methods",
            "positive affect",
            "interaction effect",
            "negative affect",
            "genetics"
        ],
        "authors": [
            {
                "name": "Guoke Ge",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Xi Zheng",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Zihong Ye",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Chunhai Shi",
                "org": "① Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            }
        ],
        "venue": "Journal of genetics and genomics = Yi chuan xue bao",
        "year": 2007
    },
    "nx8OwwdC": {
        "id": "nx8OwwdC",
        "title": "Implementation method of human-computer interaction system with large screen",
        "abstract": "To avoid camera calibration in the implementation of human-computer interaction system with large screen based on binocular stereo vision,one approximate and easy method is proposed.The distance between two cameras,left camera and the left side of screen,cameras and floor,the bottom side of screen and floor are measured to find the point of floor which is imaged as the same point with fingertip based on perspective projection model.One camera is connected with the point of floor as one space line.Two lines are intersected at the three-dimension spatial coordinate of fingertip served to position two-dimensional coordinate in the large screen.Mouse click is simulated by bend and stretch of index finger achieved by fingertip detection algorithm.Users are not aware of error even if position pointed by finger is inaccurate because mouse is seen by users when they move the hand.The method proposed is easier and more convenient than calibration method due to inaccurate position not seen by users so that system can be rapidly accomplished.",
        "keywords": [
            "perspective projection",
            "binocular vision",
            "large screen",
            "human-computer interaction"
        ],
        "authors": [
            {
                "name": "GUO Xing",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Lab of Intelligent Computing & Signal Processing of MoE,Anhui University,Hefei ,China"
            },
            {
                "name": "LIU Zhengyi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Lab of Intelligent Computing & Signal Processing of MoE,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Lab of Intelligent Computing & Signal Processing of MoE,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "Key Lab of Intelligent Computing & Signal Processing of MoE,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2012
    },
    "rrXKCy6i": {
        "id": "rrXKCy6i",
        "title": "The Three Gorges Dam: an ecological perspective",
        "abstract": "The Three Gorges Dam in China is the largest dam ever built. Its impacts on the biodiversity and ecologi- cal processes in the region are causing concern to ecologists worldwide. The dam and associated environ- mental alterations may result in a number of regional changes in terrestrial and aquatic biodiversity, as well as in ecosystem structure and functioning. The dam may also provide a rare opportunity for a grand- scale experiment in habitat fragmentation, allowing ecologists to develop and test a series of hypotheses concerning the dynamics of biodiversity and biotic communities and their responses to disturbances. Such research can help improve conservation practices, stimulate international collaborations, and promote public education on the environment.",
        "keywords": [
            "habitat fragmentation"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Jianhui Huang",
                "org": ""
            },
            {
                "name": "Xingguo Han",
                "org": ""
            },
            {
                "name": "Xianming Gao",
                "org": ""
            },
            {
                "name": "Fangliang He",
                "org": ""
            },
            {
                "name": "Mingxi Jiang",
                "org": ""
            },
            {
                "name": "Zhigang Jiang",
                "org": ""
            },
            {
                "name": "Richard B. Primack",
                "org": ""
            },
            {
                "name": "Zehao Shen",
                "org": ""
            }
        ],
        "venue": "Frontiers in Ecology and The Environment",
        "year": 2004
    },
    "bIp2d6uj": {
        "id": "bIp2d6uj",
        "title": "Analysis of genetic and genotype × environment interaction effects from embryo, cytoplasm and maternal plant for oleic acid content of Brassica napus L.",
        "abstract": "",
        "keywords": [
            "interaction effect",
            "genotype environment interaction",
            "quantitative trait",
            "genetics",
            "embryos",
            "heritability"
        ],
        "authors": [
            {
                "name": "haizhen zhang",
                "org": "zhejiang university"
            },
            {
                "name": "chunhai shi",
                "org": "zhejiang university"
            },
            {
                "name": "jianguo wu",
                "org": "zhejiang university"
            },
            {
                "name": "yuling ren",
                "org": "zhejiang university"
            },
            {
                "name": "changtao li",
                "org": "zhejiang university"
            },
            {
                "name": "dongqing zhang",
                "org": ""
            },
            {
                "name": "yaofeng zhang",
                "org": ""
            }
        ],
        "venue": "Plant Science",
        "year": 2004
    },
    "INWOgixf": {
        "id": "INWOgixf",
        "title": "Association of interleukin 27 expression and p28 gene polymorphism with chronic hepatitis B virus infection",
        "abstract": "Interleukin 27 (IL-27) is a newly discovered cytokine encoded by 2 genes, EBI3 and p28. We investigated IL-27 serum levels and p28 gene -964 A>G polymorphism in patients with chronic HBV infection and in healthy individuals, with the aims to define the correlation between IL-27 expression and chronic hepatitis B development. 168 patients, 99 recovered individuals and 152 healthy individuals were enrolled in this study. IL-27 level was measured by dual antibody sandwich-ELISA, and p28 polymorphism was determined by PCR restriction fragment length polymorphism. IL-27 serum levels were significantly higher in patients than in healthy controls (P < 0.001). Among -964 A/G polymorphisms, A/A genotype was more closely associated with patients than healthy individuals (P = 0.013). There were no differences between recovered individuals and healthy individuals in both IL-27 levels and p28 polymorphism. IL-27 levels and p28 polymorphism are associated with the development of chronic hepatitis B.",
        "keywords": [
            "chronic hepatitis b",
            "interleukin 27",
            "single nucleotide polymorphism.",
            "cytokine",
            "il-27 p28 -964 a>g polymorphism"
        ],
        "authors": [
            {
                "name": "Shiqun Wang",
                "org": ""
            },
            {
                "name": "Chengliang Zhu",
                "org": ""
            },
            {
                "name": "Rui Zhang",
                "org": ""
            },
            {
                "name": "Li Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "0G3ZTuuK": {
        "id": "0G3ZTuuK",
        "title": "Quantitative Measures and Ecological Hierarchy",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "g darrel jenerette",
                "org": "university of california riverside"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            }
        ],
        "venue": "",
        "year": 2010
    },
    "Nl9J4woG": {
        "id": "Nl9J4woG",
        "title": "Simulating the dynamics of primary productivity of a Sonoran ecosystem: Model parameterization and validation",
        "abstract": "Modeling has played a crucial role in understanding the structural and functional dynamics of forest and grassland ecosystems in the past decades, but relatively few ecosystem models have been developed for deserts. Adapting an existing desert ecosystem model to new regions with different community components and environmental settings may testify to the generality of model applicability, further verify model structure and formulations, and provide new insight into understanding desert ecosystem functioning. In this paper, we use a desert ecosystem model that was originally developed for the Chihuahuan Desert, Patch Arid Land Simulator-Functional Types (PALS-FT), to estimate the aboveground annual net primary productivity (ANPP) of a creosotebush ( Larrea tridentata )-dominated Sonoran Desert ecosystem in the Phoenix metropolitan area, home to the Central Arizona-Phoenix Long-Term Ecological Research Project (CAP LTER). We modified and parameterized the model using meteorological data, ecophysiological parameters for different plant functional types, and site characteristic data from the CAP LTER study area and an independent test site in the San Simon Valley of southeastern Arizona. Model predictions were validated and calibrated using field observations from the San Simon Valley test site. The results showed that PALS-FT was able to simulate ANPP of this typical Sonoran Desert ecosystem reasonably well, with a relative error of ±2.4% at the ecosystem level and generally less than ±25% at the functional-type level. We then used the model to simulate ANPP and its seasonal and inter-annual dynamics for a similar ecosystem in the CAP LTER study area. The model predicted average annual ANPP of 72.3 g m −2 y −1 , ranging from 11.3 g m −2 y −1 to 229.6 g m −2 y −1 in a 15-year simulation. The simulated average ANPP of the Sonoran Desert ecosystem is close to field observations in other areas of the Sonoran Desert, and the range of variation also is close to that reported by other researchers for arid and semiarid ecosystems. The dynamics of ecosystem ANPP in response to fluctuations in annual precipitation simulated by the model agreed well with the known relationship between ANPP and precipitation in arid and semiarid systems. A closer examination of this relationship at the level of plant functional types further revealed that seasonal distribution of rainfall significantly affected ANPP. A comparison between the PALS-FT model prediction and two regression models for North American warm deserts showed that both regression models underestimated the Larrea ecosystem ANPP, while the process-based PALS-FT model provided the most accurate prediction among the three models. This study provides a validation for use of the PALS-FT model to investigate Sonoran desert ecosystem responses to environmental changes. Keywords Net primary productivity Sonoran Desert Larrea PALS-FT Model parameterization Model validation Long-term ecological research 1 Introduction Arid and semiarid regions occupy over one third of the world's land surface and are home to more than 20% of the global human population ( Reynolds and Smith, 2002 ). Many drylands have been degraded by overcultivation, overgrazing, fuel gathering, urbanization, and climate change ( Schlesinger et al., 1990; Wu, 2001; Reynolds and Smith, 2002 ). With the accelerating rate of desertification around the world, especially in Africa and central Asia, the capacity of arid lands to support humans, livestock, and wild animals is decreasing substantially. Understanding the basic functioning of desert ecosystems is thus of paramount importance to combating desertification and supporting sustainable use of arid land. An important indicator of ecosystem functioning is aboveground net primary productivity. It not only reflects how well the primary producers of an ecosystem are growing, but also indicates the amount of energy available to consumers and decomposers that, in turn, drive other important ecosystem processes (e.g. biogeochemical cycles, decomposition). The primary production of desert ecosystems has been a major research topic for decades ( Noy-Meir, 1973; Fischer and Turner, 1978; Hadley and Szarek, 1981; Ludwig, 1987; Whitford, 2002 ). Studies have investigated water-use efficiency ( Webb et al., 1978; LeHouerou et al., 1988 ), below-ground productivity ( Caldwell and Camp, 1974; Bell et al., 1979 ), relationships between productivity and rainfall variability ( Ludwig, 1986; LeHouerou et al., 1988 ), and productivity of individual species or functional groups ( Chew and Chew, 1965; Burk and Dick-Peddie, 1973; Whittaker and Niering, 1975; Johnson et al., 1978; Reynolds et al., 1980, 1997; Fisher et al., 1988; Turner and Randall, 1989 ). While these studies, based on field observations and measurements, provide valuable insight into desert ecosystem processes, the generally short duration of the studies often limits the ability to obtain a clear understanding of cause and effect relationship that govern productivity in these highly temporally variable ecosystems. Thus, ecosystem simulation is a potentially powerful tool to aid in the understanding of ecosystem functioning, especially with respect to temporal processes such as climate variability and atmospheric change (e.g. changes in precipitation patterns, CO 2 , N deposition), as well as other human perturbations and management activities. However, model development with respect to desert ecosystems has lagged behind that compared with some other ecosystems, e.g. forest and grasslands (see Tiktak and van Grinsven, 1995; Ryan et al., 1996; Parton et al., 1996 ). Models for estimating terrestrial ANPP can be categorized into three types: statistical models, parametric models, and process models ( Reynolds et al., 1993; Ruimy et al., 1994 ), in which process-based models are generally considered to be more useful for understanding the mechanisms of plant growth and plant-environment interactions, and for extrapolating predictions of ecosystem responses to environmental changes. Most ecosystem models for desert ecosystems are either statistical (e.g. Noy-Meir, 1973; Webb et al., 1978; LeHouerou et al., 1988 ) or process models (e.g. Reynolds et al., 1980, 1997; Reynolds and Cunningham, 1981 ). The Patch Arid Land Simulator-Functional Types (PALS-FT) is a mechanistic process-based model developed originally for the Chihuahuan Desert ecosystem in the Jornada Basin, New Mexico, USA ( Reynolds et al., 1997 ). It has been used to study effects of disturbances on grassland-shrubland transition ( Gao and Reynolds, 2003 ), effects of rainfall variability on canopy transpiration and soil water dynamics ( Reynolds et al., 2000 ), and ecosystem responses to climate change in the Chihuanhuan Desert ( Reynolds et al., 1997 ). Applying the model and expanding these studies to new regions, longer time frames, and/or new types of environmental changes (e.g. urbanization-induced environmental changes) can further verify the structural rationality and predictive accuracy of the model and provide new insight into desert ecosystem functioning. As part of the effort to understand and predict how urbanization affects ecosystem processes in metropolitan Phoenix, Arizona, USA, a city in the Sonoran Desert (see Grimm et al., 2000 ), the main objective of this study was to adapt and evaluate the PALS-FT model for the Sonoran desert, which boasts the highest plant diversity among the four North American Deserts (Sonoran, Chihuahuan, Mojave, and the Great Basin). This is due in part to the presence of both summer and winter showers in the Sonoran Desert compared to predominately summer rainfall in the Chihuanhuan Desert and winter rainfall in the Great Basin and Mojave Deserts ( Brown, 1994; MacMahon, 2000 ). Specifically, we sought to determine whether the PALS-FT model can be applied to simulate the ecosystem ANPP of the Larrea dominated Sonoran Desert ecosystem with acceptable accuracy and consistency against field observations. We first briefly describe the structure and formulations of the PALS-FT model including modifications for application to the Sonoran Desert. The model parameter development and evaluation was accomplished using data from an independent testing site in the southeastern Sonoran Desert. The model was then used to examine seasonal and inter-annual patterns of ANPP in response to precipitation fluctuations over the northwest CAP study area of the Sonoran Desert. The PALS-FT model predictions were also compared with those of regression models that had been developed for the North American hot deserts, and the potential uses of the model to investigate urbanization effects on desert ecosystem function are discussed. 2 Model description PALS-FT is a physiologically based ecosystem model that simulates the dynamics of carbon (C), nitrogen (N), and water (H 2 O) cycling of a desert ecosystem in a daily time step, with explicit consideration of plant functional types (FTs) of shrub, subshrub, perennial grasses, forbs, C3 winter-annual, and C4 summer-annual species ( Reynolds and Cunningham, 1981; Reynolds et al., 1993, 1997, 2000; Kemp et al., 1997 ). The model was developed based on the hypothesis that changes in ecosystem structure and function are determined primarily by the dynamics of different plant FTs and soil resource distributions ( Reynolds et al., 1997 ). PALS-FT consists of four interacting modules: (i) atmospheric driving variables and surface energy budget, (ii) soil water distribution and water cycling, (iii) production of plant FTs, and (iv) nutrient (C, N) cycling. PALS-FT is similar to patch-dynamic models (e.g. Shugart, 1984; Wu and Levin, 1994, 1997 ) in that it simulates ecological processes on a “patch” of certain size. The patch size used for PALS is variable, depending upon the desired resolution, FT composition, and interaction among adjacent patches. Previous studies using PALS-FT considered relatively small patch sizes (ca. 1–30 m 2 ) in order to investigate small-scale spatial heterogeneity along a topographic gradient ( Reynolds et al., 1997, 2004; Gao and Reynolds, 2003 ). But in this study, we treated the “patch” as a generalized ecosystem unit at the scale of 1–100 km 2 for the purpose of representing a geographic area with relatively homogeneous abiotic conditions and similar ecosystem components. Model inputs and initialization includes data on climatic conditions, soil physical properties, plant and soil C and N storage, and plant ecophysiological parameters. Major model output variables include ANPP, soil evaporation, canopy transpiration, vegetation cover, soil organic matter, and soil C and N mineralization. Because PALS-FT has already been described in previous studies ( Reynolds et al., 1997, 2000, 2004 ), we provide only an overview of the general model, focusing on the elements that were modified or are particularly relevant to the objectives of our study. 2.1 Atmospheric driving variables and surface energy budget This module includes inputs of environmental driving variables (e.g. daily precipitation, maximum and minimum temperatures, solar radiation, relative humidity, ambient CO 2 concentration, and N deposition rate) and the calculation of other environmental variables using these input driving variables (e.g. day length or photoperiod, mean air temperatures, soil temperature, and vapor pressure deficit (VPD). Photoperiod is calculated as a cosine function of Julian day: (1) Photoperiod = 12 + 2 cos π × Julian     day − 172 182.5 VPD, an important variable in determining stomatal conductance, is the difference between saturated vapor pressure (VP sat ) and measured vapor pressure (VP air ) corresponding to maximum air temperature ( T max, in °C), i.e. (2) VPD ( T max ) = V P sat ( T max ) − V P air and (3) V P sat ( T max ) = 0.611 × 10 ( ( 7.5 × T max ) / ( 237.3 + T max ) ) (4) V P air = rh × V P sat ( T max ) where rh is the relative humidity (%). Surface soil temperature (at 1 cm depth) is estimated using the following empirical equations: (5) S T max = T max + 0.962 × R s − 6.63 (6) S T min = T min − 0.55 (7) S T avg = 0.77 × S T max + S T min 2 where ST max , ST min and ST avg are the maximum, minimum and average surface soil temperature (°C), respectively, T max and T min are the maximum and minimum air temperature (°C), respectively, and R s the total solar radiation (MJ m −2 day −1 ). The belowground average daily soil temperature is calculated for a relatively deep point (200 cm) using a sinusoidal function given by Campbell (1977; equation 2.8) with a mean annual deep soil temperature of 20 °C (200 cm), a surface (−1 cm) annual amplitude of mean daily temperature of 13.7 °C, and an average annual damping depth of 170 cm (which corresponds to an average thermal diffusivity of 0.003 cm 2 /s) and a phase adjustment of 91 Julian days for occurrence of mean daily surface (−1 cm) temperature. This same equation is used to calculate the soil temperature at a shallow point (50 cm) by including a site-specific harmonic term to account for asymmetry nearer the surface. Soil temperatures at depths from the surface to 50 cm are determined by interpolation of the logarithmic decay the surface temperature (Eq. (7) ) to the predicted daily mean temperature at 50 cm; and soil temperatures from 50 to 200 cm are predicted by interpolation of the logarithmic decay between these two depths. 2.2 Soil water distribution and water cycling module The water cycling module simulates daily soil evaporation, plant transpiration, and water content and movement in different soil layers ( Fig. 1 ). The water reaching the soil surface of the patch, “effective precipitation” (EP, in cm d −1 ), is estimated as a function of actual precipitation (Ppt), interception, run on, and run off, i.e. (8) EP = Ppt − intcpt + runon − runoff (9) intcpt = SS × 2 × LA I t where SS is the surface storage of water film on foliage (ave. for all FTs is ca. 0.02 cm; Reynolds et al., 2000 ), 2 is a factor accounting for the two sides of the leaf, and LAI t is the total leaf area index (m 2 m −2 ) including all plant functional types (as in Kemp et al., 1997 ). Water run-on and run-off in the simulated patch were not considered because of the negligible slope (<1%) in northwestern Phoenix and our testing site ( Fig. 4 ). Soil water is represented in 6 layers in the PALS-FT model: the upper two layers with a depth of 10 cm each and the other 4 layers with a depth of 20 cm each. Water infiltration of each layer is determined by the amount of water percolating out of the upper layer, previous water content, and water holding capacity (WHC) of the layer. Water is removed from the two top layers by evaporation and from all layers by transpiration. Evaporation is determined by soil water availability (soil water potential and relative water content, RWC) and energy available at the soil surface. Water taken up by plants is partitioned among the soil layers according to the proportions of roots in each layer for all FTs. Actual canopy transpiration is estimated by a simple energy budget model and a canopy stomatal resistance function ( Kemp et al., 1997; Reynolds et al., 2000 ). 2.3 Plant production module PALS-FT's plant production module simulates plant phenology, growth, and C allocation to different plant parts ( Fig. 2 ). Plant growth, litter fall, and plant mortality are influenced by FT-specific patterns of phenology that are controlled by water availability and extreme temperatures. The plant production module for C3 and C4 annuals and perennial grasses differs slightly from Fig. 2 in its inclusion of seed germination and reproduction for the annual FTs and regrowth from roots/rhizomes for grasses. The amount of daily plant growth for all FTs ( G j , in g dry mass m −2 ) is calculated in the same way: (10) G i = X lvs × SLA × A max , j × 12 0.46 × ( 1 − R loss ) × F c × F t where X lvs is the leaf dry mass (g), SLA the specific leaf area (m 2 g −1 ), A max, j the maximum potential net photosynthetic rate (mol CO 2 m −2 s −1 ), the value of 12 is the mass of 12 g C/mol CO 2 , 0.46 is the average C content (46%) in plant tissues, R loss the respiratory loss of photosynthetic production per day, F t the temperature influence factor (for forbs and grasses, not for shrubs), and F c (=2/ π × photoperiod × 3600) is a conversion factor (changing time unit from second to day; Monteith and Unsworth, 1990 ). The annual growth of plants calculated from Eq. (10) can be summed over the year (or season for annual FTs) and reduced by allocation to above-ground plant material to obtain a measure of aboveground net primary productivity (ANPP; herbivory is considered insignificant in the model). A max, j is estimated using the following equation ( Ehleringer, 1983 ): (11) A max , j = g j 1.6 × Ca − C i j p where g j is the stomatal conductance (mol H 2 O m −2 s −1 ), Ca the partial pressure of atmospheric CO 2 concentration (kPa), and Ci j the partial pressure of intercellular CO 2 (kPa), 1.6 is the ratio of diffusivity of H 2 O (21.2 × 10 −6 ) to CO 2 (12.9 × 10 −6 ), p is the atmospheric vapor pressure (kPa) The value of Ci j is assumed to be determined by the physiological/anatomical capacity of each FT (Ci min, j ), and is assumed to be affected by leaf N levels ( S j N ): (12) C i j = Ca − ( Ca − C i min , j ) × S j N and S j N is a linear scalar accounting for the effect of leaf N on Ci j of FT j . S j N is defined as: (13) S j N =       1 i f   N L > 1       0.1 i f   N L < 0.1 N leaf − N min leaf N max leaf − N min leaf ( = N L ) i f   0.1 ≤ N L ≤ 1 where N leaf is the currently simulated leaf N fraction, and N max leaf and N min leaf are the maximum and minimum possible leaf N fractions. Calculation of A max requires a value for stomatal conductance ( g j ). While many photosynthesis models employ schemes for predicting g in relation to feedback from carbon uptake (e.g. Ball et al., 1987; Leuning, 1995 ), other successful stomatal models have considered that g is a function of leaf water potential, VPD, light, or temperature (e.g. Jarvis, 1976; Oren et al., 1999 ). The PALS-FT model assumes that the overriding factors controlling stomatal conductance in desert plants is plant water potential (leaf hydration) and atmospheric vapor deficit (see Kemp et al., 1997 ). Thus, g j is calculated as an exponential function of FT leaf water potential ( Ψ j ) with a linear relationship to decreasing atmospheric vapor deficit (VPD in kPa): (14) g j = a × e ( b × Ψ j ) × ( 1 − 0.1 × VPD ) with a and b as FT-specific parameters defining the exponential decline in g j with decreasing Ψ j ( Table A.2 ). A daily value for leaf water potential of each FT ( Ψ j ) is calculated from the water potential of all soil layers weighted by the fraction of roots of each FT in each specific layer (see Kemp et al., 1997 ). 2.4 Nutrient cycling module The nutrient cycling module simulates the dynamics of C and N in the soil-plant-atmosphere system ( Fig. 3 ), and is a modified version of the nutrient cycling part of the CENTURY model ( Parton et al., 1988, 1993 ). Three kinds of plant litter are distinguished for each of the FTs: leaf litter, stem litter, and root litter; with the leaf and stem litter being allocated to one of two chemical pools on the soil surface (metabolic or structural C) and root litter being allocated to one of two pools in the belowground soil (also metabolic or structural C). The partitioning of litter into metabolic or structural fractions was based on literature values of residual chemical composition of litter types for each FT (see Kemp et al., 2003 ): (15) d C m , i d t = ∑ j = 1 6 d L i , j d t × Me t i , j × F c , j ,   for   metabolic   material (16) d C s , i d t = ∑ j = 1 6 d L i , j d t × ( 1 − Me t i , j ) × F c , j   for   structural   material where i = 1, 2, 3 for leaf, stem and root, j = 1, 2, 3, 4, 5, 6 for the 6 plant functional types, C m ,i and C s ,i are the C contents ( g ) in metabolic and structural material, respectively, L i,j is the litter dry mass in each litter type i-FT j combination, Met i , j is the fraction of metabolic material, and F c, j is the fraction of C content of litter type i (in dry mass) of FT j . The input rates of N from plant litter to metabolic ( N m ) and structural material ( N s ) pools are modeled similarly to C : (17) d N m , i d t = ∑ j 6 d L i , j d t × N i , j − d N s , i d t ,   for   metabolic   material (18) d N s , i d t = ∑ j = 1 6 d L i , j d t × ( 1 − Me t i , j ) × F c , j × N C i , j ,   for   structural   material where i , j , L i , j , F c, j , and Met i , j are the same as in Eqs (15) and (16) , N i,j is the N content (% of dry mass) of litter type i of FT j , and ( N / C ) i , j is the ratio of N to C for litter type i of FT j . After decomposition, the metabolic and structural material of plant litter enters into one of the three soil organic matter (SOM) pools: surface litter enters the surface active organic matter (SAOM), and belowground litter enters the active soil organic matter (ASOM) or slow soil organic matter (SSOM) according to the partitioning scheme employed in CENTURY ( Parton et al., 1993 ), and a small fraction of the C from the soil organic matter pools enters the passive soil organic matter (PSOM). The flows of C from metabolic and structural material pools to the three SOM pools and among the SOM pools are depicted in Fig. 3 and are defined by the following differential equations ( Parton et al., 1993 ): (19) d C i d t = K i × L C × A × C i ,   i = 1 , 2 (20) d C i d t = K i × A × T m × C i ,   i = 3 (21) d C i d t = K i × A × C i ,   i = 4 , 5 , 6 , 7 , 8 where C i is the C in the state variable i ; i = 1, 2, 3, 4, 5, 6, 7, 8 denote surface (leaf and stem) structural material, root structural material, active soil organic matter, surface-active organic matter, surface metabolic material, soil metabolic material, slow soil organic matter fractions, and passive soil organic matter fractions, respectively; K i is the maximum decomposition rate (day −1 ) for the i th state variable ( Table A.1 ); L C the impact of lignin content of structural material on its decomposition, T m is the effect of soil texture on ASOM turnover, and A is the combined abiotic impact of soil moisture and soil temperature on decomposition (product of the soil moisture and temperature terms). Calculations of L C , T m , and A are as in Parton et al. (1993) . The dynamics of N in decomposing organic matter is coupled directly to the flows of C through the various SOM pools. The flow of N among these pools is equal to the product of the C flows and the N/C ratio of the recipient state variable ( Parton et al., 1993 ). Specifically, the following differential equations describe the dynamics of organic N among different pools: (22) d N i d t = 1 − L S i × ( 1 − F lab , min ) × d C i d t × N C i + L S i × ( 1 − F lig , min ) × d C i d t × N C i   i = 1 , 2 (23) d N i d t = ( 1 − T m ) × d C i d t × N C i   i = 3 (24) d N i d t = ( 1 − F lab , min ) × d C i d t × ( N / C ) i   i = 4 , 5 , 6 , 7 , 8 where N i is N in state variable i ; i represent the same organic pools as in Eqs. (19)–(21) ; ( L / S ) i the ratio of lignin content to the summation of lignin and cellulose material in the i th organic pool ( Table A.2 ); ( N / C ) i the ratio of N to C for the i th organic matter pool and calculated in each time step of simulation; F lab,min is the fraction of N in labile material lost due to microbial respiration ( Table A.2 ); F lig,min is the fraction of N in non-labile material (i.e. lignin and cellulose) lost due to microbial respiration ( Table A.2 ); T s the effect of soil texture on organic N turnover ( Parton et al., 1993 ). For different organic matter pools, N associated with C lost in respiration is assumed to be mineralized. Nitrogen mineralization rates are also the products of the decomposition rates (d C i /d t ) of corresponding carbon pools, the fraction of respiratory N loss ( F lab,min ), and N / C ratio. Thus, we have: (25) d N i , min d t = 1 − L S i × ( F lab , min ) × d C i d t × N C i + L S i × ( F lig , min ) × d C i d t × N C i   i = 1 , 2 (26) d N i , min d t = T s × d C i d t × N C i   i = 3 , 4   if   N C > 1 8 ,   or   i = 7 , 8   if   N C > 1 11 ,   otherwise ,   d N i , min d t = − 0.02 (27) d N i , min d t = F lab , min × d C i d t × N C i   i = 5 , 6 where N i ,min is the N loss from the i th organic matter pool through mineralization, and all other parameters are the same as in Eqs. (22)–(24) . 3 Model parameterization The study area is located northwest of Phoenix, Arizona, USA, within the Central Arizona-Phoenix Long Term Ecological Research (CAP LTER) study area ( Fig. 4 ). The Sonoran Desert scrub biome occupies most of southwestern Arizona below 1050 m ( Turner and Brown, 1994 ). Shreve (1951) recognized seven vegetation subdivisions in the Sonoran Desert, two of which occur in the CAP LTER study area: Lower Colorado River Valley subdivision and Arizona upland subdivision. The lower Colorado River Valley subdivision occupies most of the CAP LTER study area, particularly in the northwestern portion, and is dominated by creosotebush ( Larrea tridentata ) and triangle-leaf bursage ( Ambrosia deltoidea ; Turner and Brown, 1994; MacMahon, 2000 ). The Arizona upland subdivision occurs in the northeastern part of the CAP LTER study area and is dominated by paloverde ( Cercidium microphyllum ) and cacti ( Carnegiea gigantea , Opuntia spp ), with creosotebush and bursage common as well. The rest of the CAP LTER study area is composed mainly of agricultural, urban, and riparian lands. In this study, we focus on the Larrea and Ambrosia co-dominated communities. We have classified input data to PALS-FT into two groups: site-specific parameters and plant-ecophysiological parameters. Site parameters include climatic variables, living and dead plant biomass (initial values of state variables), and soil properties (e.g. texture, organic matter content) ( Table A.1 ). The plant-ecophysiological parameters include distribution of plant root fractions in different soil layers, specific leaf area, respiratory loss ratios of daily production, minimum leaf intercellular CO 2 , contents of N, C, lignin and cellulose in leaves, stems and roots, and production allocation ratios ( Table A.2 ). The two kinds of parameter values were obtained from three sources: the CAP LTER 200-point field survey data, literature, and values used in the original PALS-FT model. The 200-point survey data were the major source for site-specific parameters, although climatic data were obtained from the Wadell Weather Station, which is located in the northwest fringe of metropolitan Phoenix about 50 km from the urban center ( Fig. 4 ). The 200-point survey data were obtained from an extensive field survey with 204 sample plots (30 m × 30 m) throughout the metropolitan area, which was carried out by CAP LTER over a 3-month period in spring 2000 ( Hope et al., 2003 ). In order to obtain a spatially dispersed and unbiased sample that allows for maximum post-design extrapolation, a dual-density randomized tessellation stratified design was used to locate the sample plots. At each location, a systematic, integrated field inventory of key abiotic, biotic, and human variables was carried out. Within each plot all woody plants (trees, shrubs, cacti, succulents) were identified, and the canopy dimensions of each individual measured to give the total volume of woody plant material. Five soil cores were taken at each site, which each were separated into 0–10 cm and 11–30 cm sections. Soil samples were analyzed to determine moisture content, organic matter content, bulk density, particle size distribution, pH, readily leachable soil nitrate and phosphate content, and inorganic and organic C content. Other measured variables included meteorological conditions, land-use and land-cover types, insect populations, surface pollens, and prokaryote and mycorrhizal diversity. In addition, information was also obtained on elevation, distance from urban center, distance from the nearest major freeway, land-use history, median family income, average age of housing stock, and human population density. PALS-FT distinguishes between living and dead biomass. The 200-point survey data only provide total vegetation cover for each plot. In order to estimate the biomass of each of the six plant functional types, we first derived an average vegetation coverage (32.9%) based on the measures in 30 of the 204 plots (see Fig. 4 ), and then calculated the plant cover of individual FTs as the product of the average total cover and the relative cover of each FT which was measured in the same area by Camp (1986) . Then, the total aboveground biomass of each FT was estimated based on empirical cover-biomass relations ( Table 1 ). Further, the biomass of leaves, stems, and roots of perennial FTs (i.e. perennial grass, subshrub and shrub) was calculated using biomass-allocation ratios derived from Chew and Chew (1965) . The dead biomass was calculated according to the dead to living biomass ratio used in the original PALS-FT model. Plant litter is split into metabolic and structural material. We estimated the size of the two litter pools by multiplying the total litter with their respective relative proportions for leaves, stems, and roots as used in the original PALS-FT model. Average SOM was estimated from the field survey data, and its relative organic C content (0.13%) was converted to C (g) per unit area (m 2 ) based on soil bulk density (1.25 g cm −3 ) and rooting depth (100 cm). This resulted in an average soil organic C of 1625 g C m −2 in the Larrea-Ambrosia community ( N = 30 plots). The partitioning of the total soil organic C into the different SOM pools was determined as in the CENTURY model ( Parton et al., 1988; Parton et al., 2001 ). All the above site-specific parameters are listed in Table A.1 . Most of the ecophysiological parameters were determined based on literature and the original PALS-FT model, which was used to analyze the effect of rainfall variability on the hydrologic cycle of the Chihuahuan Desert ecosystem ( Reynolds et al., 2000 ). The values of these parameters are listed in Table A.2 . 4 Model evaluation Model evaluation usually refers to verification and validation, but may also include model calibration and sensitivity analysis ( Swartzman and Kaluzny, 1987; Rykiel, 1996 ). Model verification is performed to ascertain the correctness of the mathematical formalism and computer code, whereas model validation is the process of evaluating the consistency and accuracy of model behavior against observations ( Jorgensen, 1986 ), or a demonstration that a model, within its domain of applicability, possesses a satisfactory range of accuracy consistent with the intended application of the model ( Rykiel, 1996 ). Because the overall model structure and belowground components have been tested elsewhere (e.g. Reynolds et al., 1997, 2000; Kemp et al., 2003 ), the emphasis here is to evaluate the accuracy of the PALS-FT prediction of ANPP of a typical Sonoran Desert ecosystem against field observations. We emphasize two validation criteria: 1) the agreement between the simulated and observed ANPP for different FTs and the entire ecosystem, and 2) the agreement between the simulated and known seasonal and inter-annual patterns of ANPP in response to precipitation fluctuations. Because available field observations on NPP of arid or semiarid ecosystems are aboveground NPP, we show only simulated aboveground NPP, although the PASL-FT model simulates belowground NPP as well. 4.1 ANPP at the FT and ecosystem levels To assess the accuracy of predicted ANPP at both the FT and ecosystem levels, we first conducted simulations for an independent test site, a Larrea tridentata -dominated plant community in the San Simon Valley, southeastern Arizona ( Fig. 4 ), where detailed field measurements of ANPP are available. The San Simon Valley site is representative of the widespread Larrea -dominated communities of the Sonoran Desert, and similar to our study site northwest of Phoenix in terms of both community structure and soil properties ( Table 2 ). In a 9.3 ha plot, Chew and Chew (1965) estimated the growth rate of L. tridentata as the addition of new nodes and its productivity as the product of the per-individual growth rate and the number of individuals for different age classes from June, 1958 to August, 1959. The aboveground productivity of other shrubs (e.g. Parthenium incanum ) and grass species was also measured similarly. We ran the model at a daily time step with the initial values of plant biomass for different functional types based on Chew and Chew (1965) ( Table A.3 ) and the actual meteorological data from the San Simon Valley weather station for the same time period that the field measurements were made. Total soil organic C was estimated as 2600 g C m −2 a based on Kenneth's (1980) investigation on the bulk density and SOM content in the San Simon Valley area ( Table 2 ), and was partitioned into different SOM pools as described in Section 2.4 (values listed in Table A.3 ). Other model input parameters, including all ecophysiological parameters, are kept the same as in Table A.2 . The simulated and observed ANPP for the San Simon Valley test site showed reasonable agreement for different FTs and the community as a whole ( Fig. 5 a ). The relative error of the simulated ANPP was ±2.4% for the whole community, and generally less than 25% for different FTs ( Fig. 5 b). Note that we used winter grass here, including perennial grass, forb, and C3 winter annuals, to represent the “fall crop” in Chew and Chew (1965) . For the study area in northwestern Phoenix where direct field measurements of ANPP are not available, we compared the model-predicted results with those in the literature. The simulations were conducted for 15 years using actual daily meteorological data from 1 January 1988 to 31 December 2002. During the 15 years, annual precipitation fluctuated between 61.8 mm (1999) and 516.5 mm (1992) ( Fig. 6 a ). Initial conditions of the Larrea-Ambrosia ecosystem are listed in Tables A.1 and A.2 . The simulated 15-year average ANPP of the ecosystem was 72.3 g m −2 y −1 , ranging from 11.3 to 229.6 g m −2 y −1 ( Fig. 6 a). The simulated mean ANPP was quite close to the observed value (70 g m −2 y −1 ) suggested by Whittaker and Likens (1973) for desert scrub communities (also see Ludwig, 1987 ). The variability in simulated ANPP also is within the range of 10–250 g m −2 y −1 estimated by Lieth (1973) for desert scrub ecosystems and close to that of 30–200 g m −2 y −1 estimated by Noy-Meir (1973) for arid ecosystems. Our modeling results showed that the mean ANPP of the Larrea ecosystem was lower in northwestern Phoenix than in southeastern Arizona. This is consistent with observations. For example, Whittaker and Niering (1975) reported that the ANPP of a Larrea community near Tucson, Arizona was 92.0 g m −2 y −1 , while Chew and Chew's (1965) field measurements showed that the ANPP of the same plant community type, located 140 km away from Tucson, could reach 130 g m −2 y −1 . Furthermore, the simulations showed that 70.9% of the total ecosystem ANPP was contributed by Larrea , 10.9% by subshrub, 3.2% by perennial grasses, 8.1% by C3 annuals, 4.0% by forbs, and 2.9% by C4 annuals. These simulated results were similar to the measurements by Chew and Chew (1965) , which showed that the relative ANPP contributions by different FTs were 69.5% for Larrea , 14.9% for other shrubs, 13.0% for fall crops, and about 1.1% for summer grasses (perennial grasses and forbs were not distinguished in their study). 4.2 Seasonal and inter-annual pattern of NPP in response to precipitation fluctuations Water availability is the primary determinant of primary productivity in arid ecosystems around the world. Can the PALS-FT model accurately simulate the seasonal and inter-annual ANPP dynamics of the Sonoran Desert ecosystem in response to precipitation fluctuations? To address this question, we further analyze the responses of ANPP to precipitation changes based on our simulations at the Phoenix study area from 1988 to 2002. Our simulation results showed that the dynamics of the ecosystem ANPP was closely related to variations in annual precipitation ( R 2 = 0.84; Fig. 6 a). At the FT level, the ANPP of shrub, subshrub, C3 winter annual and forbs also was highly correlated with annual precipitation ( R 2 = 0.80, 0.77, 0.66, and 0.64, respectively; Fig. 6 b). In contrast, the ANPP of C4 summer annuals and perennial grass did not follow the pattern of rainfall ( R 2 = 0.11 and 0.06, respectively; Fig. 6 c). In spite of the general agreement between the two, for a particular year the relationship of ANPP with annual precipitation may not be strong. For example, while the annual precipitation in 2000 and 2001 was quite different (249.25 mm in 2000 versus 161.25 mm in 2001), the simulated ANPP for the two years was quite similar (64.6 g/m 2 in 2000 and 69.3 g/m 2 in 2001). The reason was that the leaf biomass within the ecosystem model decreased dramatically in 2000 because of the drought in 1999 with only 61 mm of rainfall. This phenomenon was also observed in the field ( Bamberg et al., 1976 ). How did the seasonal distribution of rainfall affect ANPP? Did the seasonal pattern of ANPP as predicted by PALS-FT agree with existing knowledge? To address these questions, we portioned annual precipitation into three parts as in Reynolds et al. (2004) ( Fig. 7 ): spring rainfall (April 1–June 31), summer rainfall (July 1–September 31), and winter rainfall (October 1–March 31). Our analysis showed that ANPP of shrub, subshrub, C3 winter annual and forb were most closely related to winter rainfall ( R 2 = 0.68), whereas ANPP of C4 summer annual grass was most closely related to summer rainfall ( R 2 = 0.50). This general pattern was evident by visually comparing Figs. 7 and 8 . In contrast, ANPP of perennial grasses was not strongly correlated with either annual rainfall or rainfall associated with one particular season. Fig. 7 shows that most of the precipitation in the Sonoran Desert falls in winter. This seasonal distribution pattern favors the FTs of shrubs, subshrubs, C3 annuals and forbs whose growth occurs mostly in winter ( Fig. 8 ). However, actual growth responses of C4 grasses may be somewhat different from the modeled responses since the model parameterization for C4 grass that was based on black grama ( Bouteloua eriopoda ), which is not the dominant C4 grass in the northwestern CAP-LTER study area. The C4 grasses of this region could have phenology patterns and growth responses that are substantially different from black grama. 4.3 Comparison of simulated ANPP between PALS-FT and regression models Comparing the predictions by different models for same ecosystem may also provide confidence in the target model. For this reason, we chose two regression models from the literature that have been used to calculate ANPP of desert ecosystem; both developed for North American hot deserts. One is the Turner and Randall's (1989) model, which is a simple regression model that considers only annual precipitation as the determining variable of desert ANPP. The other is the Webb et al. (1983) model, which considers both abiotic factors (annual precipitation, annual potential evapotranspiration) and the current standing crop as primary determinants of Desert ANPP. The Turner and Randall's model has the form: (28) ANPP = 0.30 × ppt − 6.12 where ppt is the annual rainfall in mm. The Webb et al. model has the form: (29) ANPP = 1.8 × FSC × ∑ 1 52 2 T i / 10 × sinh ( 0.1 × max ( 0 , PPT − PET ) × Δ t i ) where FSC is the foliar standing crop (g/m 2 ), T i the weekly average temperature (°C), sin h the hyperbolic sine function, PPT is weekly precipitation (mm), PET is potential evapotranspiration (mm), Δ t i the fraction of a year. FSC was derived from Table A.3 , T i and PPT was calculated from the weather data acquired from the San Simon Valley Weather Station. PET was calculated using the equations provided in Webb et al. (1983) . The results of the regression models are presented in comparison with PALS-FT in Fig. 9 . Both regression models underestimated the Larrea ecosystem ANPP of the San Simon Valley test site by 23.9% and 34.2%, respectively, whereas the PALS-FT model provided an estimate that was closest to the observed ANPP ( Fig. 9 a). Comparing predictions of inter-annual variation in ANPP for the Larrea ecosystem in the CAP LTER study area, the Turner and Randall model prediction is more closely related to annual precipitation than the PALS-FT model prediction ( Fig. 9 b). However, the Turner and Randall model largely underestimates ANPP in wet years (e.g. 1992, 1993) and overestimates ANPP in very dry years (e.g. 1996, 1999; Fig. 9 b). We did not use the Webb's model to simulate the inter-annual ANPP variation because it requires an observed annual FSC value, which was unavailable for the CAP study area. 5 Discussion and conclusions The results of this study showed that the PALS-FT model, although originally developed for the Chihuahuan Desert, was able to simulate ANPP of the Larrea -dominated Sonoran Desert ecosystem reasonably well with only slight modifications. For the independent test site in the San Simon Valley, the relative error of the simulated ANPP was ±2.4% at ecosystem level and generally less than 25% for individual FTs. Parton et al. (1993) claimed that a relative error of ±25% should be acceptable for such simulations. The mean and variability of the simulated NPP for our Phoenix study area were also consistent with observations reported in the literature. Simulated seasonal and inter-annual dynamics of ANPP also seemed reasonable for the Sonoran Desert ecosystem. At the ecosystem level, responses of simulated ANPP to fluctuations in annual precipitation confirmed the well documented general relationship between ANPP and precipitation in arid and semiarid systems, as well as the high variability in productivity with respect to variability in annual rainfall ( LeHouerou et al., 1988 ). Further examination of the relationship for individual FTs revealed the importance of the seasonal distribution of rainfall to ANPP. In particular, winter rainfall was the better predictor of ANPP for most FTs in the Sonoran Desert ecosystem, except for C4 annuals, which are more responsive to summer rainfall. This suggests that, although the decadal pattern of ANPP can be adequately predicted by that of annual precipitation, information on the seasonal distribution of rain is needed for accurate predictions of the ecosystem ANPP for particular years. Reynolds et al. (2004) conducted a comprehensive simulation analysis to explore how plants respond to variations in precipitation and soil water availability in the three North America warm deserts. They concluded that the “pulse-reserve” model, which relates ANPP linearly to annual precipitation ( Noy-Meir, 1973; Turner and Randall, 1989; Whitford, 2002 ), is not adequate. The simulation results of Reynolds et al. (2004) showed that rainfall characteristics (e.g. seasonality and forms of rainfall) and soil water availability were also important to plant growth. In addition to rainfall and soil water availability, several other factors such as N availability, plant age, soil properties, and resource heterogeneity also can play a major role in determining ANPP ( Whitford, 2002 ). Rainfall seasonality is a particularly important driving variable, as it accounts for much of the difference among the North American warm deserts and is likely to be sensitive to CO 2 -induced climate change ( Grimm and Fisher, 1992; Grimm et al., 1997 ). The results of our study further support the notion that rainfall seasonality is crucial to plant growth in the Sonoran Desert. The comparison of predictions of the PALS-FT model with those of two published regression models showed that the PALS-FT model was more accurate in predicting ANPP of the Larrea ecosystem. The underestimation of ANPP by the two regression models was likely due to the exclusion of other important variables that may be influential for predicting ANPP, such as precipitation seasonality and event duration, intensity of storm depth, time lapse since last rainfall, and seasonal temperatures ( Whitford, 2002 ). Regression models have the advantage of fewer parameter requirements, but process-based models such as PALS-FT have more predictive and explanatory power, especially in investigating ecosystem responses to climatic and environmental changes. The PALS-FT model has a structure and includes functional relationships that are similar to some other models that have been employed for analyses in semi-arid grassland ecosystem, such as the CENTURY ( Parton et al., 1988, 1993 ) and GRASS model ( Coughenour et al., 1984 ). The PALS-FT model offers advantages over these models for use in arid shrublands with a diversity of plant FTs, since it has greater detail with respect to soil water dynamics and includes detailed growth and phenology processes of a variety of co-occurring and competing plant functional types that are likely to be found in communities of the hot deserts of southern Arizona. The adaptation and validation of PALS-FT at the local ecosystem level within the Sonoran Desert is a critical, but only first, step toward achieving our long-term goal of understanding how Sonoran Desert ecosystems respond to changes in environmental conditions caused by urbanization and climate change ( Wu and David, 2002 ). Testing model predictions against field observations and other model predictions is only part of the model evaluation process, and a good agreement between simulated and measured values alone does not guarantee the correctness of the model. To further employ the PALS-FT model in the diverse central Arizona Phoenix region, three challenges must be overcome. First, additional FTs (e.g. trees, agricultural crops) that characterize other land-use and land-cover types (e.g. residential urban area, agricultural land, and the upland subdivision of the Sonoran Desert (see Fig. 4 ) need to be incorporated into the model, or the FTs in the current version of the PALS-FT model need to be modified, reparameterized, and validated. Second, appropriate spatially explicit simulation approaches and scaling methods must be identified and used to link landscape pattern and ecosystem processes at multiple spatial scales (e.g. local ecosystem, landscape, and the whole CAP region), correspondingly, a multilayer spatial database needs to be developed for storing and updating pattern and process information at different scales. Third, variables that show large changes associated with urbanization or climate change- for example, rising temperature, elevated atmospheric CO 2 concentration, and increasing N deposition- must be manipulated in simulation experiments to evaluate their effects. Our results confirm that such simulation experiments are likely to provide a strong and realistic set of predictions with which to compare actual long-term change in this rapidly urbanizing region. Thus, this study provides a basis for further investigating how urbanization-induced environmental changes influence the functional processes of the native Sonoran Desert ecosystem. Acknowledgements We would like to thank Corinna Gries and Diane Hope for their assistance with the 200-point survey data and comments on an earlier version of the manuscript, and Alaxander Buyantuyev for creating the map of the study area. This research was supported partly by U.S. EPA's STAR program (R827676-01-0 to JW), U.S. NSF (DEB 97-14833 and DEB-0423704 to CAP-LTER), and Natural Science Foundation of China (30100021 to WS and 30028002 to JW). PRK and JFR acknowledge NSF-DEB-02-12123 and USDA Specific Cooperative Agreement 58-1270-3-070 for support of the development of PALS-FT. WS also acknowledges support from Natural Science Foundation of Guangdong Province (010551) and Heshan Open Foundation. Two anonymous reviewers and Dr. Kerry Fowler made valuable comments on the manuscript. Appendix A The PALS-FT model input parameters and their values used in this study (see Tables A.1–A.3 ). References Ball et al., 1987 J.T. Ball I.E. Woodrow J.A. Berry A model predicting stomatal conductance and its contribution to the control of photosynthesis under different environmental conditions J. Biggens Progress in Photosynthesis Research 1987 Martinus-Nijhoff Dordrecht, The Netherlands 221 224 Bamberg et al., 1976 S.A. 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Grimm S.G. Fisher Responses of arid land streams to changing climate P. Firth S.G. Fisher Climate Change and Freshwater Ecosystems 1992 Springer-Verlag New York Grimm et al., 1997 N.B. Grimm A. Chacón C.N. Dahm O.T. Lind P.L. Starkweather W.W. Wurtsbaugh Sensitivity of aquatic ecosystems to climatic and anthropogenic changes: the Basin and Range, American Southwest, and México Hydrol. Process. 11 1997 1023 1041 Hadley and Szarek, 1981 N.F. Hadley S.R. Szarek Productivity of desert ecosystems BioScience 31 1981 747 753 Hope et al., 2003 D. Hope C. Gries W. Zhu W.F. Fagan C.L. Redman N.B. Grimm A.L. Nelson C. Martin A. Kinzig Socioeconomics drive urban plant diversity Proc. Nat. Acad. Sci. 100 2003 8788 8792 Jarvis, 1976 P.G. Jarvis The interpretation of the variations in leaf water potential and stomatal conductance found in canopies in the field. Philosophical transactions of the Royal Society of London Series B Biol. Sci. 273 1976 593 610 Johnson et al., 1978 H.B. Johnson F.C. 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Whitford The effect of water and nitrogen amendments on photosynthesis, leaf demography, and resource-use efficiency in Larrea tridentata , a desert evergreen shrub Oecologia 80 1989 341 348 LeHouerou et al., 1988 H.N. LeHouerou R.L. Bingham W. Skerbek Relationship between the variability of primary production and the variability of annual precipitation in world arid lands J. Arid Environ. 15 1988 1 18 Leuning, 1995 R. Leuning A critical appraisal of a combined stomatal-photosynthesis model for C3 plants Plant Cell Environ. 18 1995 339 355 Lieth, 1973 H. Lieth Primary production: terrestrial ecosystems Human Ecol. 1 1973 303 332 Ludwig, 1986 J.A. Ludwig Primary production variability in desert ecosystems W.G. Whitford Pattern and Process in Desert Ecosystems 1986 University of New Mexico Press Albuquerque, New Mexico, USA 5 17 Ludwig, 1987 J.A. Ludwig Primary productivity in arid lands: myths and realities J. Arid Environ. 13 1987 1 7 MacMahon, 2000 J.A. MacMahon Warm deserts M.G. Barbour W.D. Billings North American Terrestrial Vegetation 2000 Cambridge University Press Cambridge, UK 285 322 Monteith and Unsworth, 1990 J.L. Monteith M.H. Unsworth Principles of Environmental Physics 2nd ed. 1990 Edward Arnold New York Moorhead and Reynolds, 1989 D.L. Moorhead J.F. Reynolds The contribution of abiotic processes to buried litter decomposition in the northern Chihuahuan Desert Oecologia 79 1989 133 135 Noy-Meir, 1973 I. Noy-Meir Desert ecosystems: environment and producers Ann. Rev. Ecol. Systematics 4 1973 25 51 Oren et al., 1999 R. Oren J.S. Sperry G.G. Katul D.E. Pataki B.E. Ewers N. Phillips K.V.R. Schäfer Survey and synthesis of intra- and interspecific variation in stomatal sensitivity to vapor pressure deficit Plant Cell Environ. 22 1999 1515 1526 Parton et al., 1988 W.J. Parton W.B. Stewart C.V. Cole Dynamics of C, N, P and S in grassland soils: a model Biogeochemistry 5 1988 109 131 Parton et al., 1993 W.J. Parton J.M.O. Scurlock D.S. Ojima T.G. Gilmanov R.J. Scholes D.S. Schimel T. Kirchner J.-C. Menaut T. Seastedt E. Garcia Moya A. Kamnalrut J.I. Kinyamario Observations and modeling of biomass and soil organic matter dynamics for the grassland biome worldwide Global Biogeochem. Cycles 7 1993 785 809 Parton et al., 1996 W.J. Parton M.B. Coughenour M.O. Scurlock D.S. Ojima T.G. Gilmanov R.J. Scholes D.S. Schimel T.B. Kirchner J.-C. Menaut T.R. Seastedt E.G. Moya A. Kamnalrut J.I. Kinyamario D.O. Hall Global grassland ecosystem modeling: development and test of ecosystem models for grassland systems A.T. Breymeyer D.O. Hall J.M. Mellillo G.I. Agren SCOPE 56: Global Change Effects on Coniferous Forests and Grasslands 1996 John Wiley & Sons New York 229 268 Parton et al., 2001 Parton, B., Ojima, D.S., Grossoand, S.D., Keough, C., 2001. CENTURY tutorial: supplement to CENTURY user's manual. Great Plains System Research Unit Technical Reprot no. 4, US-DA-ARS, Fort Collins, Colorado, USA. Reynolds and Cunningham, 1981 J.F. Reynolds G.L. Cunningham Validation of a primary production model of the desert shrub Larrea tridentata using soil-moisture augmentation experiments Oecologia 51 1981 357 363 Reynolds et al., 1993 J.F. Reynolds D.W. Hilbert P.R. Kemp Scaling ecophysiology from the plant to the ecosystem: A conceptual framework J.E. Ehleringer C.B. Field Scaling Physiological Process 1993 Academic Press San Diego 127 140 Reynolds et al., 2004 J.F. Reynolds P.R. Kemp K. Ogle R.J. Fernandez Precipitation pulses, soil water and plant responses: modifying the ‘pulse-reserve’ paradigm for deserts of North America Oecologia 141 2004 194 210 Reynolds et al., 2000 J.F. Reynolds P.R. Kemp J.D. Tenhunen Effects of long-term rainfall variability on evapotranspiration and soil water distribution in the Chihuahuan Desert: a modeling analysis Plant Ecol. 150 2000 145 159 Reynolds and Smith, 2002 J.F. Reynolds D.M.S. Smith Global Desertification: Do Humans Cause Deserts? 2002 Dahlem University Press Berlin Reynolds et al., 1980 J.F. Reynolds B.R. Strain G.L. Cunningham K.R. Knoerr Predicting primary production for forest and desert ecosystem models J.D. Hesketh J.W. Jones Predicting Photosynthesis for Ecosystem Models 1980 CRC Press Boca Raton, Florida 160 207 Vol. II Reynolds et al., 1997 J.F. Reynolds R.A. Virginia W.H. Schlesinger Defining functional types for models of desertification T.M. Smith H.H. Shugart F.I. Woodward Plant Functional Types: Their Relevance to Ecosystem Properties and Global Change 1997 Cambridge University Press Cambridge 195 216 Ruimy et al., 1994 A. Ruimy B. Saugier G. Dedieu Methodology for the estimation of terrestrial net primary production from remotely sensed data J. Geophys. Res. 99 1994 5263 5383 Ryan et al., 1996 M.G. Ryan E.R. Hunt Jr. R.E. McMurtrie G.I. Agren J.D. Aber A.D. Friend E.B. Rastetter W.M. Pulliam R.J. Raison S. Linder Comparing models of ecosystem function for temperate conifer forests. I. Model description and validation A.T. Breymeyer D.O. Hall J.M. Mellillo G.I. Agren SCOPE 56: Global Change Effects on Coniferous Forests and Grasslands 1996 John Wiley & Sons New York 313 362 Rykiel, 1996 E.J. Rykiel Jr. Testing ecological models: the meaning of validation Ecol. Modelling 90 1996 229 244 Schlesinger et al., 1990 W.H. Schlesinger J.F. Reynolds G.L. Cunningham Biological feedbacks in global desertification Science 247 1990 1043 1048 Shreve, 1951 Shreve, F., 1951. Vegetation and Flora of the Sonoran Desert. Volume I. Vegetation. Carnegie Institute of Washington Publication no. 591. Shugart, 1984 H.H. Shugart A Theory of Forest Dynamics: The Ecological Implications of Forest Succession Models 1984 Springer-Verlag New York Swartzman and Kaluzny, 1987 G.L. Swartzman S.P. Kaluzny Ecological Simulation Primer 1987 MacMillan Publishing New York Thames, 1979 Thames, J.L., 1979. Tucson validation site report. US/IBP Desert Biome Research Memorandum 77-3. In: Final Progress Reports, Validation Studies. Utah State University, Logan, Utah. Tiktak and van Grinsven, 1995 A. Tiktak H.J.M. van Grinsven Review of sixteen forest-soil-atmosphere models Ecol. Modelling 83 1995 35 53 Turner and Randall, 1989 F.B. Turner D.C. Randall Net production by shrubs and winter annuals in Southern Nevada J. Arid Environ. 17 1989 23 26 Turner and Brown, 1994 R.M. Turner D.E. Brown Sonoran desertscrub D.E. Brown Biotic Communities: Southwestern United States and Northwestern Mexico 1994 University of Utah Press Salt Lake City 181 221 Webb et al., 1978 W.L. Webb S.R. Szarek W.K. Lauenroth R.S. Kinerson M. Smith Primary productivity and water use in native forest, grassland, and desert ecosystems Ecology 59 1978 1239 1247 Webb et al., 1983 W.L. Webb W.K. Lauenroth S.R. Szarek R.S. Kinerson Primary production and abiotic controls in forests, grasslands, and desert ecosystems in the United States Ecology 64 1983 134 151 Werk et al., 1983 K.S. Werk J. Ehleringer I.N. Forseth C.S. Cook Photosynthetic characteristics of Sonoran Desert winter annuals Oecologia 59 1983 101 105 Whitford, 2002 W.G. Whitford Ecology of Desert Systems 2002 Cambridge University Press Cambridge, UK Whittaker and Likens, 1973 R.H. Whittaker G.E. Likens Primary production: the biosphere and man Human Ecol. 1 1973 357 369 Whittaker and Niering, 1975 R.H. Whittaker W.A. Niering Vegetation of the Santa Catalina mountains, Arizona. V. Biomass, production, and diversity along the elevation gradient Ecology 56 1975 771 790 Wu, 2001 J. Wu Desertification R. Robinson Plant Sciences 2001 Macmillan Reference USA New York Wu and David, 2002 J. Wu J.L. David A spatially explicit hierarchical approach to modeling complex ecological systems: theory and applications Ecol. Modelling 153 2002 7 26 Wu and Levin, 1994 J. Wu S.A. Levin A spatial patch dynamic modeling approach to pattern and process in an annual grassland Ecol. Monographs 64 1994 447 464 Wu and Levin, 1997 J. Wu S.A. Levin A patch-based spatial modeling approach: conceptual framework and simulation scheme Ecol. Modelling 101 1997 325 346",
        "keywords": [
            "larrea",
            "long-term ecological research",
            "model parameterization",
            "model validation",
            "net primary productivity",
            "pals-ft",
            "sonoran desert",
            "relative error",
            "long term",
            "ecosystem model",
            "parametrisation",
            "primary production",
            "primary productivity",
            "seasonality",
            "environmental change",
            "net primary production",
            "regression model",
            "ecosystem",
            "parameterization",
            "ecology"
        ],
        "authors": [
            {
                "name": "Weijun Shen",
                "org": "South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Paul R. Kemp",
                "org": "Biology Department, University of San Diego, 5998 Alcala Pk., San Diego, CA 92110, USA"
            },
            {
                "name": "James F. Reynolds",
                "org": "Department of Botany and Nicholas School of the Environment and Earth Science, Duke University, Durham, NC 27708-0340, USA"
            },
            {
                "name": "Nancy B. Grimm",
                "org": "Faculty of Ecology, Evolution and Environmental Sciences, School of Life Sciences, Arizona State University, P.O. Box 874501, Tempe, AZ 85287-4501, USA"
            }
        ],
        "venue": "Ecological Modelling",
        "year": 2005
    },
    "mYZfWuVG": {
        "id": "mYZfWuVG",
        "title": "Inhibition of Hepatitis B Virus Replication and Gene Expression through Vector Mediated Small Interfering RNA",
        "abstract": "In this study,we constructed a fast screening system with target gene and luciferase reporter gene.Four siRNA molecules were designed to target the HBV S gene and investigated the effect of short interfering RNA on HBV viral replication and its gene expression.Results indicated that one out of the four siRNA molecules designed could inhibit the expression of HBs gene successfully based on semi-quantitative RT-PCR,ELISA,western blot and fluorescencequantitative PCR analyses.In addition,the selected siRNA was able to reduce the amount of HBV core associated DNA significantly,an intracellular replicative intermediate.Therefore,it provides a powerful tool for the study of gene function and implicates a potential application in the treatment of viral infection.",
        "keywords": [
            "hepatitis B virus",
            "small interfering RNA",
            "RNA interference"
        ],
        "authors": [
            {
                "name": "WU Hao",
                "org": "College of Life Sciences,Wuhan University/ State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "WU Kailang",
                "org": "College of Life Sciences,Wuhan University/ State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "ZHU Ying",
                "org": "College of Life Sciences,Wuhan University/ State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "WU Jianguo",
                "org": "College of Life Sciences,Wuhan University/ State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "YANG Fuhua",
                "org": "College of Life Sciences,Wuhan University/ State Key Laboratory of Virology,Wuhan ,Hubei,China"
            }
        ],
        "venue": "Journal of Wuhan University(Natural Science Edition)",
        "year": 2006
    },
    "CKWFDby2": {
        "id": "CKWFDby2",
        "title": "The Caulobacter heat shock sigma factor gene rpoH is positively autoregulated from a sigma32-dependent promoter.",
        "abstract": "Sigma factor sigma32, encoded by rpoH, is required for the recognition of heat shock genes during normal growth conditions and in response to heat shock and other stresses. Unlike the well-studied Escherichia coli rpoH gene, which is transcribed from four promoters recognized by either a sigma70 (sigmaD)- or sigma24 (sigmaE)-containing RNA polymerase, the Caulobacter crescentus rpoH gene is transcribed from two promoters, P1 and P2. In this study, we have examined the structure and expression of these promoters and shown that the rpoH P2 promoter is sigma32 dependent. We present evidence here that P2 is specifically recognized and transcribed by the reconstituted C. crescentus Esigma32 RNA polymerase holoenzyme. We show that site-directed mutations within either the -10 or the -35 regions of P2 have substantial effects on the levels of transcription by the Esigma32 polymerase predicted from the sigma32 promoter consensus sequence. The mutations have similar effects in vivo as assayed with rpoH-lacZ transcription fusions. Analysis of the rpoH P1 promoter provided evidence that it is sigma70 dependent. S1 nuclease protection assays of rpoH P1- and P2-specific expression after heat shock at 42 or 50 degrees C and during synchronous cell division cycles under normal growth conditions showed that the two promoters are differentially regulated. Mutations within the rpoH P2 promoter consensus sequences abolished the response to heat shock induction in C. crescentus. We conclude from these results that, unlike rpoH genes studied previously in other bacteria, the major transcriptional response of the C. crescentus rpoH gene to heat shock depends on positive autoregulation of the sigma32-dependent promoter.",
        "keywords": [],
        "authors": [
            {
                "name": "J Wu",
                "org": "Department of Molecular Biology, Princeton University, New Jersey 08544-1014, USA."
            },
            {
                "name": "A Newton",
                "org": ""
            }
        ],
        "venue": "Journal of bacteriology",
        "year": 1997
    },
    "jwNiGb1a": {
        "id": "jwNiGb1a",
        "title": "Development of enzyme-linked immunosorbent assay method for anti-B lymphocyte stimulator autoantibodies and its preliminary clinical application",
        "abstract": "Objective:To investigate the prevalence of the antibodies against the B lymphocyte stimulator(BlyS),(BlyS-Ab) in patients with clinical diseases,and to explore the role of BlyS-Ab in the pathogenesis of autoimmune diseases(AID).Methods:By optimizing experimental conditions,we developed ELISA methods for serum levels of BlyS-Ab,followed by methodological and clinical application assessment and investigation of the relationship of serum BlyS-Ab levels with the titers of anti-nucleus antibodies(ANA) and other autoantibodies.Results:The intra-assay precision,namely the average coefficient values of BlyS-Ab was 7.8%,and the specific inhibition rate for BlyS-Ab by series concentration of BlyS was up to 77.3%.Clinical investigation revealed that the serum levels of BlyS-Ab was significantly higher in patients with autoimmune diseases(including SLE,RA,myasthenia gravis) and other medical cases(such as allergic purpurics,chronic nephritis,etc.) than in the normal control(P<0.01).Significant positive correlation was found between the serum levels of BlyS-Ab and ANA titers.In 63 patients with BlyS-Ab positive,there were 59 with ANA positive,whereas in another 64 with BlyS-Ab negative,there were 30 with ANA negative,60th with significant association and moderate coincidence(χ2=26.387,Kappa=0.404,P<0.001).To some extent,BlyS-Ab was also significantly associated with anti-dsDNA,anti-SSA,anti-SSB and anti-RNP antibodies(P<0.01 or P<0.05).Conclusion:The ELISA method for human serum BlyS-Ab was successfully established,and the result of this assay was specific,sensitive and reliable.The detection of the serum levels of BlyS-Ab is potentially helpful to the diagnosis of autoimmune diseases.",
        "keywords": [
            "B lymphocyte stimulator",
            "Autoantibody",
            "Autoimmune disease"
        ],
        "authors": [
            {
                "name": "YU Wei",
                "org": "Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Yan",
                "org": "Department of Laboratory,Nanjing Drum Tower Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Xiao-jun",
                "org": "Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2007
    },
    "WgNPKKpm": {
        "id": "WgNPKKpm",
        "title": "Genetic analysis of methionine content in indica-japonica hybrid rice (Oryza sativa L.) at different grain developmental stages",
        "abstract": "Genetics of methionine content in indica-japonica hybrid rice (Oryza sativa L.) was studied in 35 F1 hybrids derived from crossing 7 male-sterile indica rice cultivars with 5 restorer japonica rice cultivars. Two genetic models and their corresponding statistical methods for quantitative traits of triploid endosperm in cereal crops were used for the analysis. One is the unconditional model, which refers to the analysis of cumulative measurements along the developmental stages, while another is the conditional model, which relates to analysis throughout the developmental stages. Results showed that methionine content of indica-japonica hybrid rice was controlled by expression of triploid endosperm nuclear genes, cytoplasm genes, diploid maternal plant nuclear genes, and their genotype-environment interaction effects. Dominant effects were important at the first three developmental stages, while additive effects were important at the next two stages of grain development under both unconditional and conditional analyses. With regard to the components of heritability, maternal and cytoplasm general heritabilities and their environmental interaction heritabilities were important. It was suggested that enhancing methionine content could be more efficient when selection is based on maternal plants in early breeding generations. © 2004 Kluwer Academic Publishers.",
        "keywords": [
            "conditional genetic variance",
            "developmental genetics",
            "genetic variance",
            "heritability",
            "indica-japonica hybrid rice",
            "methionine content",
            "quality",
            "quantitative trait",
            "genotype environment interaction",
            "genetics",
            "cumulant"
        ],
        "authors": [
            {
                "name": "Xiao-ming Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chun-hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Shen-Hai Yue",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "Jian-guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Geng Liang Bao",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Euphytica",
        "year": 2004
    },
    "iNOSFHGF": {
        "id": "iNOSFHGF",
        "title": "The Screening of Mutants and Construction of Mutant Population for Cultivar \"9311\" in Rice(Oryza sativa L.)",
        "abstract": "Rice has become an established model system in the last decade and the organism chosen in the study of the cereal genomes.In order to find more mutants in the same genetic background,the seeds of indica rice cultivar 9311 were treated with γ-rays or EMS(ethyl methan sulfonate).Some mutants with the variations of leaf,stalk,panicle or root traits were found in the progenies,which the mutation frequency was 5.62%.Four hundred and sixty-five out of the 675 mutants were induced by γ-rays,and the other 210 mutants by EMS.Comparing with the EMS mutagenesis population,more mutants were produced in γ-rays mutagenesis population.But some mutants,such as the purple leaf sheath mutant and lesion resembling disease mutant,were only found in EMS mutagenesis population.The mutant library created will be helpful for gene identification and gene functional analysis.",
        "keywords": [
            "EMS(Ethyl Methan Sulfonate)",
            "Mutant",
            "γ-rays",
            "Rice(Oryza sativa L.)",
            "Mutagenesis"
        ],
        "authors": [
            {
                "name": "YE Jun",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "WU Jian-Guo",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "DU Jing",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "ZHENG Xi",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "ZHANG Zhi",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "SHI Chun-Hai",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou ,Zhejiang,China"
            }
        ],
        "venue": "Acta Agronomica Sinica",
        "year": 2006
    },
    "Vk5YU7vW": {
        "id": "Vk5YU7vW",
        "title": "Implementing of Massive Log Analysis System Based on Parallel Computing",
        "abstract": "On the basis of analyzing log type and features deeply,design and implement a massive log processing system based on parallel computing.It adopts the method of cluster to collect log in parallel way,store in the distributed file system,and analyze log by parallel computing.The system achieves log collection and analysis through automated processing,can effectively carry on security maintenance,system performance optimization,system failure check after the system deployment.The system combines distributed and cloud computing solutions to improve efficiency of log processing,solves the major problems of massive logs processing effectively,provides a complete and effective solutions for massive logs processing.",
        "keywords": [
            "log processing",
            "cloud computing",
            "distributed computing",
            "distributed file system"
        ],
        "authors": [
            {
                "name": "BAI Chao",
                "org": "Anhui University,Hefei ,China"
            },
            {
                "name": "YANG Jing",
                "org": "Department of Computer,College of Electronic Engineering of PLA,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2013
    },
    "3G7cYpAF": {
        "id": "3G7cYpAF",
        "title": "China’s new rural “separating three property rights” land reform results in grassland degradation: Evidence from Inner Mongolia",
        "abstract": "Abstract   China is currently implementing the “separating three property rights” (STPR) reform to consolidate rural land. This reform divides rural land property rights into three components: nontradable ownership, nontradable contractual rights and tradable land use rights. The STPR reform adopts the rental of grassland use rights, a market-oriented approach, as the main arrangement for grassland consolidation. However, this arrangement may undermine the cornerstones of grassland restoration, which are the security of grassland property and payments for ecosystem services (PES) policies. As an alternative to the market-oriented approach, cooperatives are also encouraged to consolidate grassland use rights. We used a natural experiment approach to systematically examine how two different land consolidation arrangements affected key grassland ecosystem services in Inner Mongolia. In rented grasslands, all ecosystem services except provisioning services degenerated severely. Traded grassland use rights were perceived as insecure, which led to predatory land use by tenants. In contrast, cooperative-managed grasslands showed no serious degradation in ecosystem services. However, these cooperatives limited their group size by chief kinship to avoid the free-rider problem; thus, they are unlikely to become a primary channel of grassland consolidation. Because PES policy subsidies are still allocated to grassland contractors rather than to tenants, these policies are irrelevant to the conservation of rented grasslands. Based on our analysis, we suggest several ways to improve this new rural land property reform to avoid a major wave of grassland degradation in China.",
        "keywords": "",
        "authors": [
            {
                "name": "Ang Li",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Xiangshan, Beijing 100093, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, PR China"
            },
            {
                "name": "Xueyao Zhang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Xiangshan, Beijing 100093, PR China"
            },
            {
                "name": "Jianguo Xue",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Xiangshan, Beijing 100093, PR China"
            },
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, PR China"
            },
            {
                "name": "Xingguo Han",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Xiangshan, Beijing 100093, PR China"
            },
            {
                "name": "Jianhui Huang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, Xiangshan, Beijing 100093, PR China"
            }
        ],
        "venue": "Land Use Policy",
        "year": 2018
    },
    "4Rqbkmp1": {
        "id": "4Rqbkmp1",
        "title": "Design of Thermal Power Plant Circulating Water On-line Monitor and Water-saving Management",
        "abstract": "For the purpose of increasing the recycle rate of cooling water in thermal power plants,the designed system of circulating water on-line monitor and water-saving management in the paper can keep circulating cooling water from depositing and prevent pipelines from eroding in order to heighten the concentration ratio of recycling cooling-water system and obtain the water-saving target.The range control algorithm has been applied in the control loop and the entire system has been constituted with the way of wireless network.",
        "keywords": [
            "concentration ratio",
            "water-saving management",
            "on-line monitor",
            "circulating cooling water"
        ],
        "authors": [
            {
                "name": "ZHANG Zhi-min",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "HUANG Zi-ying",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            }
        ],
        "venue": "Instrumentation Technology",
        "year": 2011
    },
    "BjhpsTah": {
        "id": "BjhpsTah",
        "title": "The anti-hyperlipidemia activities of six herbs before and after fermentation with white rot fungi",
        "abstract": "Hyperlipidemia has high morbidity.We explored the novel activities of six Chinese herbs before and after fermentation for preventing hyperlipidemia.The herbs were fermented with white rot fungi Ganoderma lucidum,a strain of EN2.Lovastatin was used as the positive control.Mice were treated with those herbs before and after fermentation treatment for 15 d and then injected peritoneally with Triton 3393.After the treatment,the serum total cholesterol(TC)and triglyceride(TG)were measured.More-over,the changes of the ingredients of those herbs were analyzed by fingerprint chromatography.The results showed that Herba leonuri before fermentation,Ramulus mori and Caulis lonicerae after fermentation,Radix sophorae flavescentis before and after fermentation showed activities to prevent hypertriglyceridemia,while Ramulus mori and Herba leonuri before fermentation showed activities to prevent hypercholesterolemia.In addition,some new ingredients were appeared after fermentation.In conclusion,the novel activities of these herbs to prevent hyperlipidemia were identified and the new ingredients that emerged after fermentation warrant further exploration.",
        "keywords": [
            "Anti-hyperlipidemia effect White rot fungi Fermentation Chinese medicine"
        ],
        "authors": [
            {
                "name": "Jun-Yan Tao",
                "org": "State Key Laboratory of Virology,College of Life Sciences,Wuhan University,Wuhan ,China"
            },
            {
                "name": "Guo-Hua Zheng",
                "org": "School of Pharmacy,Hubei College of Traditional Chinese Medicine,Wuhan ,China"
            },
            {
                "name": "Lei Zhao",
                "org": "Department of Hepatology and Infectious Disease,Union Hospital,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "Zhi-Jun Huang",
                "org": "Wuhan Jianmin Pharmacy of TCM Co.Ltd.,Wuhan ,China"
            },
            {
                "name": "Qiong-Guang Zhang",
                "org": "Wuhan Jianmin Pharmacy of TCM Co.Ltd.,Wuhan ,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "College of Life Science & Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "Xiao-Yu Zhang",
                "org": "College of Life Science & Technology,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "中国药学(英文版)",
        "year": 2009
    },
    "trON4any": {
        "id": "trON4any",
        "title": "Resampling Methods for the Extrema of Certain Conditional Sample Functions",
        "abstract": "In this paper some resampling methods for the extrema of certain conditional functions are examined.Some methods of estimator ofγ~2 are offered,including delete- d jackknife,delete-1 jackknife and bootstrap method.And the properties of the resulted statistics are discussed.",
        "keywords": [
            "bootstrap estimation",
            "asymptotic variance",
            "extrema of sample functions",
            "jackknife estimation"
        ],
        "authors": [
            {
                "name": "WU JIANGUO",
                "org": "Department of Mathematics,Hunan College of Finance and Economics,Changsha "
            }
        ],
        "venue": "Acta Mathematicae Applicatae Sinica",
        "year": 2006
    },
    "kiSX8VjI": {
        "id": "kiSX8VjI",
        "title": "Correlation between levels of hemocysteine and the markers of prothrombotic state in elderly patients with hypertension",
        "abstract": "Objective To evaluate the clinical values of homocysteine and explore the correlation between plasma homocysteine and prothrombotic state in elderly patients with hypertension.Methods Samples from 56 patients and 20 healthy controls were determinated for the levels of homocysteine(Hcy),fibrinogen(Fib),d-dimer(D-D),von Willebrand factor(vWF),tissue plasminogen activator(t-PA),plaminogen activator inhibitor-1(PAI-1),protein C(PC) and p-selectin(CD62p).Results Compared with the controls,there were elevated levels of plasma Hcy,Fib,D-D,vWF,t-PA and CD62p,and reduced levels of PC and PAI-1 in patients with hypertension.The levels of Hcy,Fib,D-D,vWF,t-PA and CD62p in patients with high Hcy and secondary hypertension were significantly higher(but lower for PC and vWF) than those in patients with normal Hcy and essential hypertension,respectively.Higher blood pressure was,more remarkably the levels of plasma Hcy,Fib,D-D,vWF,t-PA and CD62p increased,and more markedly the levels of PC and PAI-1 decreased.There was positive correlation between Hcy and any one of Fib,D-D,vWF,t-PA and CD62p,and negative correlation between Hcy and PC as well as PAI-1.Conclusions Hcy is associated with prothrombotic state in elderly patients with hypertension.The phasma Hcy level is a valuable indicator for the prevention and evaluation of thrombosis in patients with hypertension.",
        "keywords": [
            "cysteine",
            "aged",
            "thrombosis",
            "hypertension",
            "blood pressure",
            "physiopathology",
            "glycoproteins",
            "blood proteins"
        ],
        "authors": [
            {
                "name": "FEI Xian-ming",
                "org": "Center of Laboratory Medicine,Zhejiang Provincial People's Hospital, Hangzhou,China"
            },
            {
                "name": "LU Fei-feng",
                "org": "Center of Laboratory Medicine,Zhejiang Provincial People's Hospital, Hangzhou,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Center of Laboratory Medicine,Zhejiang Provincial People's Hospital, Hangzhou,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Healthcare",
        "year": 2009
    },
    "U7lA50gU": {
        "id": "U7lA50gU",
        "title": "Study of new serum parameters in patients with rheumatoid arthritis and its preliminary application",
        "abstract": "Objective To establish and perfect the serological test system for diagnosis of rheumatoid arthritis(RA),search for new autoantibody markers of RA,and explore the role and clinical significance of these parameters in occurrence and development of RA.Methods Human fibrinogen(hFib) and bovine type Ⅱ collagen(bCⅡ) were modified and citrullinated by peptidylarginine deiminase(PAD),respectively.CⅡ peptide(CⅡ 260-272) and cyclic citrullinated peptide(CCP) were selected as immobilized antigens.The enzyme-linked immunosorbent assay(ELISA) for autoantibodies against Cit-hFib,Cit-bCⅡ,CⅡ peptide and CCP antigens were established.The positive rates of these autoantibodies in clinical patients and the relationship with other laboratory parameters were also analyzed.The diagnostic value of these autoantibodies was assessed in the patients with RA.Results The positive rates of anti-Cit-hFib and anti-Cit-bCⅡ antibody in the patients with RA were 59.4% and 56.3% respectively,and were significantly higher than those in the patients with other diseases and healthy controls(P<0.01).The sensitivity and specificity of these antibodies for RA diagnosis were significantly higher than those of anti-hFib and anti-bCⅡ antibody.The diagnostic value of anti-CⅡ peptide antibody was close to that of anti-CCP antibody.The diagnostic sensitivities of anti-CⅡ peptide and anti-CCP antibody for RA were of 67.2% and 68.8%,and the specificities were of 95.3% and 97.8%.The positive/negative predictive values were of 76.8%/88.0% and 92.6% /93.1% respectively.The positive/negative likelihood ratios were 14.3/31.3 and 0.34/0.32 respectively.Youden indexes were up to 0.625 and 0.666.In 13 patients with early stage of RA,the frequencies of both anti-CⅡ peptide and anti-CCP antibody were up to 76.9%.The area under the ROC curve of anti-CCP antibody was of 0.946,and anti-CⅡ peptide antibody was of 0.924.The combination of anti-CⅡ peptide and anti-CCP antibody or anti-CⅡ peptide and rheumatoid factor could effectively improve the diagnostic level of RA.The results of correlation analysis and symmetric measurement showed that each autoantibody was significantly correlated with anti-CCP antibody.Among them,anti-Cit-hFib and anti-Cit-bCⅡ antibodies presented synchrony with anti-CCP antibody to a certain extent(0.4 <Kappa<0.75).The detectable rates of the 2 autoantibodies in symmetric measurements were 84.4%(54/64) and 78.1%(50/64),respectively.Both the autoantibodies significantly,positively correlated with C-reactive protein(CRP) and erythrocyte sedimentation rate(ESR)(P<0.01),suggesting that serum levels of the autoantibodies closely associated with the activity of RA and serum levels of anti-CⅡ peptide antibody decreased with the improved clinical symptoms of RA patients.Conclusion Citrullinated protein and its corresponding autoantibodies played an important role in occurrence and development of RA.Anti-CⅡ peptide and anti-citrullinated protein antibodies,including anti-CCP,anti-Cit-hFib and anti-Cit-bCⅡ antibodies,closely associated with disease activity of RA.These autoantibodies may be developed as new serological monitoring and effective diagnostic parameters for RA.",
        "keywords": [
            "autoantibody",
            "type Ⅱ collagen",
            "rheumatoid arthritis",
            "fibrinogen",
            "citrullinated protein",
            "immunoenzyme technique"
        ],
        "authors": [
            {
                "name": "YU Wei",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WANG Jin-hua",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "BAI Cai-qin",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GAO Pei-fang",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "FANG Guo-xiang",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "XIA Hai-ping",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Xiao-jun",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Department of Centre Laboratory,Institute of Clinical Laboratory Medicine,PLA,Nanjing General Hospital of Nanjing Military Command,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Chinese Journal of Clinical Laboratory Science",
        "year": 2011
    },
    "NRTfsdtS": {
        "id": "NRTfsdtS",
        "title": "Model for Prevention and Control of Hepatitis B Guided by Health Management Idea",
        "abstract": "Hepatitis B virus infection has now been a very serious public health problem in China.It seriously impairs the people′s health and socio-economic development,meanwhile causes a series of social problems.Based on the nature of the health management cycle,and focused on the current hepatitis B virus infection situation and its damage to the economic of China,this paper analyzes the practical significance of the health management implementation for hepatitis B,and designs a health management schema for the prevention and control of hepatitis B.",
        "keywords": [
            "Prevention",
            "Health management",
            "Hepatitis B",
            "Control"
        ],
        "authors": [
            {
                "name": "ZHANG Yue",
                "org": ",et al.Health Policy & Management,Nanjing Medical University,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ",et al.Health Policy & Management,Nanjing Medical University,Nanjing ,China"
            },
            {
                "name": "LU Jian-Hua",
                "org": ",et al.Health Policy & Management,Nanjing Medical University,Nanjing ,China"
            }
        ],
        "venue": "Chinese General Practice",
        "year": 2011
    },
    "OlQYlvkl": {
        "id": "OlQYlvkl",
        "title": "NS5 Conservative Site Is Required for Zika Virus to Restrict the RIG-I Signaling.",
        "abstract": "During host-virus co-evolution, cells develop innate immune systems to inhibit virus invasion, while viruses employ strategies to suppress immune responses and maintain infection. Here, we reveal that Zika virus (ZIKV), a re-emerging arbovirus causing public concerns and devastating complications, restricts host immune responses through a distinct mechanism. ZIKV nonstructural protein 5 (NS5) interacts with the host retinoic acid-inducible gene I (RIG-I), an essential signaling molecule for defending pathogen infections. NS5 subsequently represses K63-linked polyubiquitination of RIG-I, attenuates the phosphorylation and nuclear translocation of interferon regulatory factor 3 (IRF3), and inhibits the expression and production of interferon-β (IFN-β), thereby restricting the RIG-I signaling pathway. Interestingly, we demonstrate that the methyltransferase (MTase) domain of NS5 is required for the repression of RIG-I ubiquitination, IRF3 activation, and IFN-β production. Detailed studies further reveal that the conservative active site D146 of NS5 is critical for the suppression of the RIG-I signaling. Therefore, we uncover an essential role of NS5 conservative site D146 in ZIKV-mediated repression of innate immune system, illustrate a distinct mechanism by which ZIKV evades host immune responses, and discover a potential target for anti-viral infection.",
        "keywords": [
            "IFN-β",
            "IRF3",
            "NS5",
            "RIG-I",
            "ZIKV",
            "methyltransferase",
            "ubiquitination"
        ],
        "authors": [
            {
                "name": "Aixin Li",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Yingchong Wang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Keli Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Feng Xiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Dingwen Hu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Lixia Hui",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yuqian Feng",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Geng Li",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Qiuping Tan",
                "org": "Guangdong LongFan Biological Science and Technology Company, Foshan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "Frontiers in immunology",
        "year": 2020
    },
    "9ifRygCv": {
        "id": "9ifRygCv",
        "title": "The Soil Organic Carbon and Total Nitrogen Content on the Northern Slope of Qi Lian Mountain and Its Relationship with Altitude,Vegetation and Climatic Factors",
        "abstract": "The SOC(soil organic carbon) and total nitrogen content in different elevations on the northern slope of Qilian Mountain and its relationship with climatic factors and vegetation were investigated.The results showed that the SOC content in 0-5cm,5-15cm and 15-30cm soil depth were all the lowest at low elevations(2300m and 2800m) and high elevation(3600m),while which was the highest at middle altitudes(3000-3500m).Additionally,the SOC in these depths followed the pattern:shrub meadows>forest>alpine meadows>steppe>desert steppe.The total soil nitrogen in 0-5cm and 5-15cm soil depth were both the highest at 3400m and 3500m altitudes and were the lowest at 2300m and 2800m elevations,and it in 15-35cm soil depth were the highest at 3400m elevation and the lowest at 2300m and 2800m elevations.Additionally,the total soil nitrogen in 0-5cm soil depth followed the pattern:shrub meadows>alpine meadows>forest>steppe>desert steppe,and which in 5-15cm and 15-35cm soil depths followed the pattern:shrub meadows>forest>alpine meadows>steppe>desert steppe.The soil C:N in 0-5cm,5-15cm and 15-30cm soil depths were the lowest at low elevations(2300m and 2800m),while it was the highest at altitudes of 3000m and 3200m.Additionally,soil C:N in these soil depths followed the pattern:forest>shrub meadows>alpine meadows>steppe>desert steppe.The SOC,total soil nitrogen and soil C:N generally decreased with increasing mean annual temperature and increased with increasing annual precipitation.The correlation coefficients between the content of SOC and total soil nitrogen was higher without considering the difference of elevation;while the coefficients was different greatly in different soil depth and elevation when considering the difference of elevations.",
        "keywords": [
            "soil organic carbon",
            "Qi Lian Mountain",
            "climatic factors",
            "vegetation",
            "total soil nitrogen"
        ],
        "authors": [
            {
                "name": "AI Li",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "LIU Jian-quan",
                "org": ""
            },
            {
                "name": "CHANG Wei",
                "org": ""
            },
            {
                "name": "TIAN Zi-qiang",
                "org": ""
            },
            {
                "name": "CHANG Xue-xiang",
                "org": ""
            },
            {
                "name": "LI Han-dong",
                "org": ""
            },
            {
                "name": "LIU Xian-de",
                "org": ""
            }
        ],
        "venue": "Chinese Horticulture Abstracts",
        "year": 2010
    },
    "L70xuERi": {
        "id": "L70xuERi",
        "title": "Identification of the resistance of 16 rice varieties to Rice dwarf virus",
        "abstract": "Susceptibilities of 16 bred or extended rice varieties to Rice dwarf virus(RDV) were investigated using pathogenesis rate as an indicator of resistance grade.The results showed that significant variance existed among the varieties.Among the 16 varieties studied,1 variety was immune to RDV,accounting for 6.25%;6 varieties were middle-resistant,accounting for 37.5%;3 varieties were middle-susceptible,accounting for 18.75%;6 varieties were disease-sensitive,accounting for 37.5%.The latent period(11-15 d) of susceptible variety,was significantly shorter than that of resistance variety(15-20 d).Further investigations revealed that the infection rate of rice variety correlated with the ration of leafhopper(Nephotrttix cincticeps) carrying virus,and the correlation coefficient was 99.99%.The results of identification were as follows: both of RDV resistance and insect resistance were high in Xieyou 46(Oryza sativa L.ssp.indica cv Xieyou 46);Yixiang 2292(Oryza sativa L.ssp.indica cv Yixiang 2292) had resistance to RDV;Ganyou 734(Oryza sativa L.ssp.indica cv Ganyou 734) was an immune variety,which was proved to be an ideal material for RDV resistance breeding.",
        "keywords": [
            "insect-resistant character",
            "leafhopper(Nephotrttix cincticeps)",
            "disease-resistant character",
            "variety resistance",
            "Rice dwarf virus(RDV)"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            },
            {
                "name": "BA Jun-wei",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            },
            {
                "name": "LI Guan-yi",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            },
            {
                "name": "LIN Qi-ying",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            },
            {
                "name": "WU Zu-jian",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            },
            {
                "name": "XIE Lian-hui",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University,Key Laboratory of Plant Virology of Fujian Province,Fuzhou,Fujian ,China"
            }
        ],
        "venue": "Journal of Fujian Agriculture and Forestry University(Natural Science Edition)",
        "year": 2010
    },
    "6jiuXOvF": {
        "id": "6jiuXOvF",
        "title": "Application of Lipopeptide Biosurfactants in Soaping",
        "abstract": "Lipopeptide biosurfactants have the characteristic of low toxicity and no pollution.First reactive yellow KD-3G and reactive blue KN-G were used to dye cotton fabrics,then lipopeptide biosurfactants were used to soap as soaping agent.The results of experiment show that soaping effect and anti-staining property of lipopeptide biosurfactants are better than conventional soaping agent.The optimum process conditions were as follows: concentration of lipopeptide biosurfactants 0.10 g/L,bath ratio 1∶30,pH 9,reactive yellow KD-3G had been used to soap cotton fabric for 20 min at 80℃,reactive blue KN-G had been used to cotton fabric for soaping 30 min at 90℃.",
        "keywords": [
            "soaping",
            "anti-staining",
            "lipopeptide biosurfactants"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Yancheng College of Textile Technology,Yancheng ,China"
            },
            {
                "name": "Wang Lan",
                "org": "Yancheng College of Textile Technology,Yancheng ,China"
            }
        ],
        "venue": "Shandong Textile Science & Technology",
        "year": 2011
    },
    "MOjwkyf4": {
        "id": "MOjwkyf4",
        "title": "The Application of ECS-100 in Drawing Motion Control of Short Fiber Production",
        "abstract": "Control system for short fiber production is a combination of process control and motion control.The application of WebField ECS-100 in short fiber production was introduced.WebField ECS-100 can accomplish speed control of drawing process by connecting SIEMENS MICROMASTER 430 VF controlling based on Profibus agreement with Profibus-DP main station input board,WebField ECS-100 can also manage process parameters like temperature,pressure,etc.",
        "keywords": [
            "Short fiber",
            "Process control",
            "Motion control"
        ],
        "authors": [
            {
                "name": "ZHANG Kun",
                "org": "Supcon Group Co Ltd,Hangzhou ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            }
        ],
        "venue": "Machine Tool & Hydraulics",
        "year": 2008
    },
    "RB2dVQC9": {
        "id": "RB2dVQC9",
        "title": "A hierarchical analysis of the relationship between urban impervious surfaces and land surface temperatures: spatial scale dependence, temporal variations, and bioclimatic modulation",
        "abstract": "ContextUnderstanding how urban impervious surfaces (UIS) affect land surface temperatures (LST) on different scales in space and time is important for urban ecology and sustainability.",
        "keywords": "",
        "authors": [
            {
                "name": "Qun Ma",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Chunyang He",
                "org": "Beijing Normal University"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2016
    },
    "CfCMN5b2": {
        "id": "CfCMN5b2",
        "title": "Plant diversity enhances productivity and soil carbon storage.",
        "abstract": "Despite evidence from experimental grasslands that plant diversity increases biomass production and soil organic carbon (SOC) storage, it remains unclear whether this is true in natural ecosystems, especially under climatic variations and human disturbances. Based on field observations from 6,098 forest, shrubland, and grassland sites across China and predictions from an integrative model combining multiple theories, we systematically examined the direct effects of climate, soils, and human impacts on SOC storage versus the indirect effects mediated by species richness (SR), aboveground net primary productivity (ANPP), and belowground biomass (BB). We found that favorable climates (high temperature and precipitation) had a consistent negative effect on SOC storage in forests and shrublands, but not in grasslands. Climate favorability, particularly high precipitation, was associated with both higher SR and higher BB, which had consistent positive effects on SOC storage, thus offsetting the direct negative effect of favorable climate on SOC. The indirect effects of climate on SOC storage depended on the relationships of SR with ANPP and BB, which were consistently positive in all biome types. In addition, human disturbance and soil pH had both direct and indirect effects on SOC storage, with the indirect effects mediated by changes in SR, ANPP, and BB. High soil pH had a consistently negative effect on SOC storage. Our findings have important implications for improving global carbon cycling models and ecosystem management: Maintaining high levels of diversity can enhance soil carbon sequestration and help sustain the benefits of plant diversity and productivity.",
        "keywords": [
            "aboveground net primary productivity",
            "belowground biomass",
            "human disturbance",
            "soil carbon storage",
            "species richness"
        ],
        "authors": [
            {
                "name": "Shiping Chen",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Wantong Wang",
                "org": "South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China."
            },
            {
                "name": "Wenting Xu",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Yang Wang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Hongwei Wan",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Dima Chen",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Zhiyao Tang",
                "org": "College of Urban and Environmental Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Xuli Tang",
                "org": "South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China."
            },
            {
                "name": "Guoyi Zhou",
                "org": "South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China."
            },
            {
                "name": "Zongqiang Xie",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Daowei Zhou",
                "org": "Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130012, China."
            },
            {
                "name": "Zhouping Shangguan",
                "org": "State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau, Northwest A&F University, Yangling 712100, China."
            },
            {
                "name": "Jianhui Huang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China."
            },
            {
                "name": "Jin-Sheng He",
                "org": "Key Laboratory of Adaptation and Evolution of Plateau Biota, Northwest Institute of Plateau Biology, Chinese Academy of Sciences, Xining 810008, China."
            },
            {
                "name": "Yanfen Wang",
                "org": "College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China."
            },
            {
                "name": "Jiandong Sheng",
                "org": "Key Laboratory of Soil and Plant Ecological Processes, College of Grassland and Environment Sciences, Xinjiang Agricultural University, Urumqi 830052, China."
            },
            {
                "name": "Lisong Tang",
                "org": "State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China."
            },
            {
                "name": "Xinrong Li",
                "org": "Key Laboratory of Stress Physiology and Ecology in Cold and Arid Regions, Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China."
            },
            {
                "name": "Ming Dong",
                "org": "Key Laboratory of Hangzhou City for Ecosystem Protection and Restoration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China."
            },
            {
                "name": "Yan Wu",
                "org": "Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China."
            },
            {
                "name": "Qiufeng Wang",
                "org": "Synthesis Research Center of Chinese Ecosystem Research Network, Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China."
            },
            {
                "name": "Zhiheng Wang",
                "org": "College of Urban and Environmental Sciences, Peking University, Beijing 100871, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes & Resource Ecology, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "F Stuart Chapin",
                "org": "Institute of Arctic Biology, University of Alaska, Fairbanks, AK 99775."
            },
            {
                "name": "Yongfei Bai",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; yfbai@ibcas.ac.cn."
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 2018
    },
    "ITHBFyD0": {
        "id": "ITHBFyD0",
        "title": "Genetic analysis of endosperm, cytoplasmic and maternal effects for histidine and arginine in indica rice (Oryza sativa L.) across environments",
        "abstract": "Genetic main effects and genotype x environment (GE) interaction effects for amino acids histidine (His) and arginine (Arg) in milled rice were analyzed by using the genetic models for quantitative traits of triploid endosperm. Nine cytoplasmic male sterile lines as females and five restoring lines as males were included in an incomplete diallel cross in two environments. Results indicated that the His content and Arg content were mainly controlled by genetic main effects, whereas the ratios of His content to protein content (RHP) or Arg content to protein content (RAP) were mainly affected by GE effects. Since genetic variances involved were found significantly for all traits, the genetic controlling of these two amino acids could be simultaneously affected by the endosperm, cytoplasm and maternal genetic effects. For genetic main effects, the cytoplasm and maternal additive effects for these two amino acids possessed high percentage of 60.2-70.9%, which indicated that selection for these amino acids based on maternal performance could be more effective than that based on single seed. The total narrow-sense heritabilities were high for Arg and RAP with 82.4% and 82.3%, and low for His and RHP with 46.4% and 18.2%, respectively. Since general heritabilities for these two amino acids were found to be much larger than GE interaction heritability, the selection advance for these traits could be expected at different environments. Most cytoplasmic and maternal additive correlations were significantly positive and dominance interaction correlations were also important among all the pairwise traits. Indirect selection of these two amino acids applied in rice breeding was discussed.",
        "keywords": [
            "Arginine",
            "Genetic correlation",
            "Genetic effect",
            "Genotype x environment interaction effect",
            "Heritability",
            "Histidine",
            "Rice (Oryza sativa L.)"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Xiaoming Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Tomita Katsura",
                "org": "Fukui Agricultural Experiment Station(Fukui Agric. Experiment Station,Fukui Agricultural Experiment Station),Fukui,Japan"
            }
        ],
        "venue": "Cereal Research Communications",
        "year": 2004
    },
    "o6dTnsrY": {
        "id": "o6dTnsrY",
        "title": "Analysis of the genetic effects on the trait of seed amino acid content in crops",
        "abstract": "The progresses of both the traditional and recent studies on the genetic effects on the content of seed amino acids were reviewed.One of the most important objectives in plant quality breeding is to increase the amino acid content in crop seeds.The trait of seed amino acid content was thought to be controlled by multiple genes.In the previous studies,the methods of generation average or additive-dominant genetic model were utilized to analyze the genetic effects on this trait,and the results showed that the genetic mechanisms controlling the content of amino acids in seeds were quite different among crops.Recently,much complex quantitative genetic models and statistical methods were used,and the results indicated that the content of seed amino acids was regulated not only by the triploid endosperms(diploid embryo),cytoplasm,and the genetic main effects of diploid maternal plants,but also by the GE interaction effects,though the extent to which was different among these effects.",
        "keywords": [
            "seed",
            "genetic models",
            "amino acid content",
            "quantitative trait",
            "quantitative traits",
            "genes",
            "amino acids",
            "genotype environment interaction",
            "endosperm",
            "cytoplasm",
            "chemical composition"
        ],
        "authors": [
            {
                "name": "CHEN Guo-lin",
                "org": "Department of A-gronomy,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "SHI Chun-hai",
                "org": ""
            }
        ],
        "venue": "Acta Agriculturae Zhejiangensis",
        "year": 2009
    },
    "UTkhQ0xp": {
        "id": "UTkhQ0xp",
        "title": "p2 of Rice stripe virus (RSV) interacts with OsSGS3 and is a silencing suppressor: P2 of rice stripe virus is a silencing suppressor interacting with OsSGS3",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "liuyang hu",
                "org": ""
            },
            {
                "name": "ying liu",
                "org": ""
            },
            {
                "name": "zhengjie yuan",
                "org": ""
            },
            {
                "name": "dongsheng jia",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "donglai xiao",
                "org": ""
            },
            {
                "name": "zhenguo du",
                "org": ""
            },
            {
                "name": "lianhui xie",
                "org": ""
            },
            {
                "name": "zujian wu",
                "org": ""
            },
            {
                "name": "qiying lin",
                "org": ""
            },
            {
                "name": "taiyun wei",
                "org": ""
            },
            {
                "name": "zhao han",
                "org": ""
            }
        ],
        "venue": "Molecular Plant Pathology",
        "year": 2011
    },
    "CXNoymql": {
        "id": "CXNoymql",
        "title": "Phenotypic and Candidate Gene Analysis of a New Floury Endosperm Mutant () in Rice",
        "abstract": "A floury endosperm mutant, , was isolated from the M generation of japonica rice cultivar Nipponbare following ethyl methane sulfonate mutagenesis. The  mutant produced a white-core endosperm compared to the transparent endosperm of the wild type (WT). The results from scanning electron microscope showed that the  mutant grains comprised of round and loosely packed starch granules, some of which were compounded. The analysis for cooking and nutrition quality traits indicated that the values of gel consistency, gelatinization temperature, and rapid viscosity analysis profile of  grains were lower than those of the WT. Besides, the protein content, the contents of nine different amino acids, and the thermodynamic parameters of   and Δ  in  were also different from those of the WT. Genetic analysis revealed that  mutation was controlled by a single recessive gene. The  gene was mapped between InDel markers R1M30 and ID1-12 on rice chromosome 1. In the candidate region of the Nipponbare genome, an annotated gene, LOC_Os01g44220 which encodes a large subunit of putative ADP-glucose pyrophosphrylase named  was considered the optimal candidate. Cloning and sequencing of LOC_Os01g44220 in different plants of the  mutants revealed a single nucleotide mutation (G→A) in the open reading frame region, which led to a substitution of an acidic amino acid Glu (E) by a basic amino acid Lys (K) accordingly. Furthermore, the mutant site is close to the functional domain which interacts with the ADP-Glc. In brief, these results suggested that the  is a new mutant of .",
        "keywords": [
            "osagpl2-3",
            "flo6",
            "OsAPL2",
            "Floury endosperm",
            "ADP-glucose pyrophosphrylase",
            "Map-based cloning",
            "Rice"
        ],
        "authors": [
            {
                "name": "Dapeng Zhang",
                "org": "Agronomy Department, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Agronomy Department, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Yujiang Zhang",
                "org": "Agronomy Department, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Agronomy Department, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Plant Molecular Biology Reporter",
        "year": 2012
    },
    "uND7yabE": {
        "id": "uND7yabE",
        "title": "In vitro antiviral activity of lutein against hepatitis B virus.",
        "abstract": "Despite the availability of an effective vaccine, the hepatitis B virus (HBV) infection and its treatment remains one of the foremost public health problems in the world. The present study was performed in order to investigate the anti-HBV activity of lutein in vitro. The antiviral activity of lutein was examined by detecting the levels of HBsAg, HBeAg and extracellular HBV DNA in stable HBV-producing human hepatoblastoma HepG2 2.2.15 cells. It was found that lutein effectively suppressed the secretion of HBsAg from HepG2 2.2.15 cells in a dose-dependent manner, and it also suppressed the amount of extracellular HBV DNA. A luciferase reporter gene assay was used to determine the effects of lutein on the activities of HBV promoters. The results showed that lutein inhibited the activity of HBV full-length promoter (Fp). These data indicate that lutein possesses an anti-HBV activity and exerts its antivirus effects via inhibition of HBV transcription.",
        "keywords": [
            "hbv promoter",
            "hbv dna",
            "hbeag",
            "hbsag",
            "lutein",
            "hepatitis b virus"
        ],
        "authors": [
            {
                "name": "Ran Pang",
                "org": ""
            },
            {
                "name": "Jun-Yan Tao",
                "org": ""
            },
            {
                "name": "Shu-Ling Zhang",
                "org": ""
            },
            {
                "name": "Lei Zhao",
                "org": ""
            },
            {
                "name": "Xin Yue",
                "org": ""
            },
            {
                "name": "Yue-Feng Wang",
                "org": ""
            },
            {
                "name": "Pian Ye",
                "org": ""
            },
            {
                "name": "Ji-Hua Dong",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            }
        ],
        "venue": "Phytotherapy research : PTR",
        "year": 2010
    },
    "L5xqh7P7": {
        "id": "L5xqh7P7",
        "title": "Tradeoffs and thresholds in the effects of nitrogen addition on biodiversity and ecosystem functioning: evidence from inner Mongolia Grasslands",
        "abstract": "",
        "keywords": [
            "aboveground biomass",
            "ecological restoration",
            "ecosystem management",
            "eurasia steppe",
            "nitrogen enrichment",
            "plant functional group composition",
            "species richness",
            "nitrogen"
        ],
        "authors": [
            {
                "name": "YONGFEI BAI",
                "org": ""
            },
            {
                "name": "JIANGUO WU",
                "org": ""
            },
            {
                "name": "CHRISTOPHER M. CLARK",
                "org": ""
            },
            {
                "name": "SHAHID NAEEM",
                "org": ""
            },
            {
                "name": "QINGMIN PAN",
                "org": ""
            },
            {
                "name": "JIANHUI HUANG",
                "org": ""
            },
            {
                "name": "LIXIA ZHANG",
                "org": ""
            },
            {
                "name": "XING GUOHAN",
                "org": ""
            }
        ],
        "venue": "Global Change Biology",
        "year": 2010
    },
    "a2dSWyq3": {
        "id": "a2dSWyq3",
        "title": "Evolving perspectives on biofuels in the United States",
        "abstract": "Abstract Biofuels represent an important source of renewable energy and may play a crucial role in developing sustainable energy strategies for many countries and the world as a whole. The pros and cons of biofuels, however, have been debated both scientifically and politically. They remain a topic of controversy. In this paper, the evolvement of the perspectives and policies on biofuels in the United States in the past several decades was reviewed. Four different periods, that is, the period prior to 1978 (marked by the passage of the Energy Act in 1978); 1978–1989 (ending with the passage of the Clean Air Act Amendments of 1990); 1990–2004 (ending with the passage of the energy act of 2005); and 2005 to the present, which were characterized by defining events of major policy importance were identified. Each time period was assessed using the Ostrom institutional analysis and development (IAD) framework to show the impact of the evolving interests and influences of global players on policy choices related to biofuels in the United States. The US has a long history of supporting corn-based ethanol and more recently advanced biofuels. Changes in perspectives on biofuels from largely unrelated groups led to changes in policy and market dynamics. Until the late 1990s, most perspectives and policies tended to be aligned and significantly supportive of corn-based ethanol in the United States. In the early 2000s, it became clear that the complications associated with first generation biofuels and corn-based ethanol in particular, were too numerous and too severe to overlook. The need for better options has spurred interest in new technologies and more environmentally benign feedstocks, but, there is little prospect for biofuels playing a significant role in the near term without greater alignment among key players.",
        "keywords": [
            "renewable energy",
            "biofuels",
            "energy sustainability"
        ],
        "authors": [
            {
                "name": "Lisa C. Dirks",
                "org": "Global Institute of Sustainability and School of Life Sciences, Arizona State University, Tempe, Arizona, 85287, USA"
            },
            {
                "name": "Gary W. Dirks",
                "org": "Global Institute of Sustainability and School of Life Sciences, Arizona State University, Tempe, Arizona, 85287, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Global Institute of Sustainability and School of Life Sciences, Arizona State University, Tempe, Arizona, 85287, USA ; Sino-US Center for Conservation, Energy and Sustainability Science (SUCCESS), Inner Mongolia University, Hohhot, 010021, China"
            }
        ],
        "venue": "Frontiers in Energy",
        "year": 2012
    },
    "b38bcIXW": {
        "id": "b38bcIXW",
        "title": "Effect of the knee position during wound closure after total knee arthroplasty on early knee function recovery.",
        "abstract": "This study investigated the effect of the knee position during wound closure on early knee function recovery after total knee arthroplasty (TKA).This study included 80 primary total knee arthroplasties due to osteoarthritis. The patients were randomized according to the type of wound closure: extension group for full extension and flexion group for 90° flexion. The incision of articular capsule was marked for precise wound alignment. In the flexion group, the knee was kept in high flexion for 1 to 2 min after wound closure. The two groups were treated with the same postoperative rehabilitation exercises. The range of motion (ROM), visual analogue scale (VAS) score of anterior knee pain, Knee Society Score (KSS) and postoperative complications were assessed at 6 weeks, 3 months and 6 months, postoperatively.At 6 weeks and 3 months postoperatively, the ROM in flexion group was 98.95 ± 10.33° and 110.05 ± 4.93° respectively, with 87.62 ± 8.92° and 95.62 ± 6.51° in extension group, respectively; The VAS score of anterior knee pain in flexion group was 2.02 ± 1.38 and 2.21 ± 0.87, respectively, with 2.57 ± 1.07 and 2.87 ± 0.83 in extension group, respectively. The ROM and VAS pain score of the two groups were significantly different at these two time points, with no significant difference at 6 months postoperatively. The two groups were not significantly different in KSS, and no apparent complication was observed at three time points.Marking the articular capsule incision, wound closure in flexion and high flexion after wound closure can effectively decrease anterior knee pain after TKA and promote the early recovery of ROM.",
        "keywords": [
            "orthopedics",
            "bioinformatics",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Siqun Wang",
                "org": "Department of Orthopaedics,Huashan Hospital Affiliated to Fudan University,Shanghai,China"
            },
            {
                "name": "Jun Xia",
                "org": "Department of Orthopaedics,Huashan Hospital Affiliated to Fudan University,Shanghai,China"
            },
            {
                "name": "Yibin Wei",
                "org": "Department of Orthopaedics,Huashan Hospital Affiliated to Fudan University,Shanghai,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Orthopaedics,Huashan Hospital Affiliated to Fudan University,Shanghai,China"
            },
            {
                "name": "Gangyong Huang",
                "org": "Department of Orthopaedics,Huashan Hospital Affiliated to Fudan University,Shanghai,China"
            }
        ],
        "venue": "Journal of orthopaedic surgery and research",
        "year": 2014
    },
    "IloVWnYc": {
        "id": "IloVWnYc",
        "title": "PERSPECTIVES AND METHODS OF SCALING",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "JIANGUO WU",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability 85287-4501 Tempe AZ USA"
            },
            {
                "name": "HARBIN LI",
                "org": "Center for Forested Wetlands Research USDA Forest Service Southern Research Station 29414 Charleston SC USA"
            }
        ],
        "venue": "",
        "year": 2006
    },
    "sB1GU97G": {
        "id": "sB1GU97G",
        "title": "The problems of weak sustainability and associated indicators",
        "abstract": "ABSTRACTSustainability is a grand challenge of our time. While there is a universal recognition that sustainability includes social, economic, and environmental components, the relationship and interchangeability between these components has been debated, resulting in three distinct sustainability perspectives: weak, strong, and absurdly strong sustainability. However, despite this active debate, few have questioned which types of sustainability commonly utilized index forms actually measure. Here we provide such an analysis, focusing on the interplay between the mathematical forms of sustainability indices and the three sustainability perspectives. We show that the computational underpinning of a sustainability index defines what type of sustainability the index is capable of measuring, while also providing alternative forms. We then provide a brief example of how these different sustainability perspectives can radically alter measured sustainability. We end with a call for sustainability researchers to ...",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell C. Wilson",
                "org": "School of Life Sciences, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, Arizona State University, Tempe, AZ, USA; School of Sustainability, Arizona State University, Tempe, AZ, USA"
            }
        ],
        "venue": "International Journal of Sustainable Development and World Ecology",
        "year": 2017
    },
    "jYql8NXi": {
        "id": "jYql8NXi",
        "title": "Morphological characteristics and gene mapping of a novel bent pedicel branch (bpb1) mutant in rice]",
        "abstract": "Rice pedicels are tightly associated with the yield of grain. In the present study, a novel and stable pedicel mutant bpb1 (bent pedicel branch 1) was obtained from the wild type \"Zhenong 7\" after 60Co γ-ray treatment. The mutant had the typical phenotype of bent pedicel branches with multiple abnormal phenotypes, such as longer pedicels, short panicles, and dwarfism. Detail examination using scanning electron microscopy revealed that the pedicel epidermal hairs and stomas in the mutant were smaller than those in the wild type. The epidermal and sclerenchymatous cells were arranged irregularly, and the cells in the bend region of pedicels became smaller and arranged closely. The transverse observation of the mutant pedicel branches showed that the small vascular bundles arranged differently from those of the wild type. Genetic analysis indicated that the abnormal phenotypes were controlled by a single recessive gene. Using the F2 mapping population from the bpb1 mutant crossed with the japonica rice variety \"Zhenongda 104\", the bpb1 gene was mapped in a 343 kb region between two SSR markers, RM21537 and RM21552, at the long arm of chromosome 7. Because no homologous gene was found in this region until now, bpb1 might be a novel gene related to the pedicel development and growth. This study could be beneficial to future cloning and functional analysis of the bpb1 gene.",
        "keywords": [
            "gene mapping",
            "morphological characteristics",
            "bent pedicel branchs",
            "rice",
            "mutant"
        ],
        "authors": [
            {
                "name": "Yun-Long Yang",
                "org": " Agronomy Department,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": " Agronomy Department,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Yuan-Fei Zhou",
                "org": " Agronomy Department,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Chun-Hai Shi",
                "org": " Agronomy Department,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2013
    },
    "vo1Ai1Cp": {
        "id": "vo1Ai1Cp",
        "title": "Urban landscape matrix affects avian diversity in remnant vegetation fragments: Evidence from the Phoenix metropolitan region, USA",
        "abstract": "Abstract Biodiversity conservation in urban areas has become increasingly important as cities have expanded to cover larger proportions of landscapes across the world. The careful planning of habitat reserves within urbanized areas has the potential to make significant contributions to regional biodiversity. We surveyed the passerine community in 15 habitat reserves within the Phoenix metropolitan region and explored the relationships between community composition and urban land uses surrounding the reserves. Diversity of different guilds was affected in substantially different ways by reserve characteristics and surrounding urban land use. Guilds responded to land use at all three scales included in the study – 200 m, 1000 m and 2500 m. The responses of four guilds, synanthropic, non-synanthropic, insectivore and feeding generalist, were well predicted by the factors considered here. Reserve characteristics (area, shape, isolation), particularly area, had effects on all four of these guilds with non-synanthropic and insectivore species responding positively to area, while synanthropic and feeding generalist species responded negatively. Land use type surrounding the reserves had significant effects on all of these guilds, except for feeding generalists. High density, high diurnal activity land uses decreased diversity, while medium density, low diurnal activity uses increased the diversity of some guilds, particularly insectivores, probably by providing supplemental habitat. This study provides new evidence from an arid urban landscape that not only reserve characteristics, but also surrounding urban land use should be considered during conservation planning, especially if non-synanthropic or insectivore species are among the targeted species.",
        "keywords": [
            "Urban ecology",
            "Habitat fragmentation",
            "Avian",
            "Nesting guilds",
            "Feeding guilds",
            "Urban land use",
            "Habitat reserve",
            "Synanthropy"
        ],
        "authors": [
            {
                "name": "Jennifer Litteral",
                "org": "School of Life Sciences, Arizona State University, P.O. Box 874601, Tempe, AZ, 85287-4601, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences &amp; School of Sustainability, Arizona State University, P.O. Box 874601, Tempe, AZ, 85287-4601, USA"
            }
        ],
        "venue": "Urban Ecosystems",
        "year": 2012
    },
    "wh3uVIAM": {
        "id": "wh3uVIAM",
        "title": "An essential, multicomponent signal transduction pathway required for cell cycle regulation in Caulobacter.",
        "abstract": "Cell differentiation and division in Caulobacter crescentus are regulated by a signal transduction pathway mediated by the histidine kinase DivJ and the essential response regulator DivK. Here we report genetic and biochemical evidence that the DivJ and DivK proteins function to control the activity of CtrA, a response regulator required for multiple cell cycle events, including flagellum biosynthesis, DNA replication, and cell division. Temperature-sensitive sokA (suppressor of divK) alleles were isolated as extragenic suppressors of a cold-sensitive divK mutation and mapped to the C terminus of the CtrA protein. The sokA alleles also suppress the lethal phenotype of a divK gene disruption and the cold-sensitive cell division phenotype of divJ mutants. The relationship between these signal transduction components and their target was further defined by demonstrating that the purified DivJ kinase phosphorylates CtrA, as well as DivK. Our studies also showed that phospho-CtrA activates transcription in vitro from the class II flagellar genes and that their promoters are recognized by the principal C. crescentus sigma factor sigma73. We propose that an essential signal transduction pathway mediated by DivJ, DivK, and CtrA coordinates cell cycle and developmental events in C. crescentus by regulating the level of CtrA phosphorylation and transcription from sigma73-dependent class II gene promoters. Our results suggest that an unidentified phosphotransfer protein or kinase (X) is responsible for phosphoryl group transfer to CtrA in the proposed DivJ --> DivK --> X --> CtrA phosphorelay pathway.",
        "keywords": [
            "signal transduction",
            "transcription factors",
            "cell division",
            "dna replication",
            "sequence alignment",
            "phosphorylation",
            "sigma factor",
            "alleles",
            "dna binding proteins",
            "cell differentiation",
            "signal transduction pathway",
            "histidine kinase",
            "cell cycle",
            "genetics",
            "cell cycle regulation"
        ],
        "authors": [
            {
                "name": "J Wu",
                "org": "Department of Molecular Biology, Princeton University, Princeton, NJ 08544"
            },
            {
                "name": "N Ohta",
                "org": "Department of Molecular Biology, Princeton University, Princeton, NJ 08544"
            },
            {
                "name": "A Newton",
                "org": "Department of Molecular Biology, Princeton University, Princeton, NJ 08544"
            }
        ],
        "venue": "Proceedings of the National Academy of Sciences of the United States of America",
        "year": 1998
    },
    "CnTPZ32Z": {
        "id": "CnTPZ32Z",
        "title": "Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage.",
        "abstract": "Dengue virus (DENV) infection causes several diseases ranging from dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome characterized by endothelial dysfunction, vascular leakage, and shock. Here, we identify a potential mechanism by which DENV induces tissue injury and vascular leakage by promoting the activation of interleukin (IL)-1β. DENV facilitates IL-1β secretion in infected patients, mice, human peripheral blood mononuclear cells (PBMCs), mouse bone marrow-derived macrophages (BMDMs), and monocyte-differentiated macrophages (THP-1)  activating the NLRP3 inflammasome. The accumulated data suggest that IL-1β probably induces vascular leakage and tissue injury in interferon-alpha/beta receptor 1 deficient C57BL/6 mice (  C57BL/6), whereas IL-1 receptor antagonist (IL-1RA) alleviates these effects of IL-1β. Finally, administration of recombinant IL-1β protein results in vascular leakage and tissue injury in C57BL/6 mice. Together, the accumulated results demonstrate that IL-1β contributes to DENV-associated pathology and suggest that IL-1RA acts as a potential agent for the treatment of DENV-associated diseases.",
        "keywords": [
            "IL-1RA",
            "IL-1β",
            "NLRP3 inflammasome",
            "dengue virus",
            "inflammatory response",
            "vascular leakage"
        ],
        "authors": [
            {
                "name": "Pan Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Zhenyang Yu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Zizhao Lao",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Wei Zhang",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Miaomiao Shen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Feng Xiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Muhammad Adnan Shereen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wen Zhang",
                "org": "Guangdong LongFan Biological Science and Technology, Foshan, China."
            },
            {
                "name": "Qiuping Tan",
                "org": "Guangdong LongFan Biological Science and Technology, Foshan, China."
            },
            {
                "name": "Yuntao Liu",
                "org": "Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Xiaohong Liu",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Geng Li",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "Frontiers in microbiology",
        "year": 2019
    },
    "5cM0JWgq": {
        "id": "5cM0JWgq",
        "title": "Correction: EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wenbiao Wang",
                "org": ""
            },
            {
                "name": "Feng Xiao",
                "org": ""
            },
            {
                "name": "Pin Wan",
                "org": ""
            },
            {
                "name": "Pan Pan",
                "org": ""
            },
            {
                "name": "Yecheng Zhang",
                "org": ""
            },
            {
                "name": "Fang Liu",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Yingle Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2018
    },
    "6czRxw3J": {
        "id": "6czRxw3J",
        "title": "Regulation of Viral RNA Synthesis by the V Protein of Parainfluenza Virus 5.",
        "abstract": "ABSTRACT  Paramyxoviruses include many important animal and human pathogens. The genome of parainfluenza virus 5 (PIV5), a prototypical paramyxovirus, encodes a V protein that inhibits viral RNA synthesis. In this work, the mechanism of inhibition was investigated. Using mutational analysis and a minigenome system, we identified regions in the N and C termini of the V protein that inhibit viral RNA synthesis: one at the very N terminus of V and the second at the C terminus of V. Furthermore, we determined that residues L16 and I17 are critical for the inhibitory function of the N-terminal region of the V protein. Both regions interact with the nucleocapsid protein (NP), an essential component of the viral RNA genome complex (RNP). Mutations at L16 and I17 abolished the interaction between NP and the N-terminal domain of V. This suggests that the interaction between NP and the N-terminal domain plays a critical role in V inhibition of viral RNA synthesis by the N-terminal domain. Both the N- and C-terminal regions inhibited viral RNA replication. The C terminus inhibited viral RNA transcription, while the N-terminal domain enhanced viral RNA transcription, suggesting that the two domains affect viral RNA through different mechanisms. Interestingly, V also inhibited the synthesis of the RNA of other paramyxoviruses, such as Nipah virus (NiV), human parainfluenza virus 3 (HPIV3), measles virus (MeV), mumps virus (MuV), and respiratory syncytial virus (RSV). This suggests that a common host factor may be involved in the replication of these paramyxoviruses.   IMPORTANCE  We identified two regions of the V protein that interact with NP and determined that one of these regions enhances viral RNA transcription via its interaction with NP. Our data suggest that a common host factor may be involved in the regulation of paramyxovirus replication and could be a target for broad antiviral drug development. Understanding the regulation of paramyxovirus replication will enable the rational design of vaccines and potential antiviral drugs.",
        "keywords": "",
        "authors": [
            {
                "name": "Yang Yang",
                "org": ""
            },
            {
                "name": "Yang Yang",
                "org": ""
            },
            {
                "name": "James Zengel",
                "org": ""
            },
            {
                "name": "Minghao Sun",
                "org": ""
            },
            {
                "name": "Katrina Sleeman",
                "org": ""
            },
            {
                "name": "Khalid Timani",
                "org": ""
            },
            {
                "name": "Jason Aligo",
                "org": ""
            },
            {
                "name": "Paul A. Rota",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Biao He",
                "org": ""
            },
            {
                "name": "Biao He",
                "org": ""
            }
        ],
        "venue": "Journal of Virology",
        "year": 2015
    },
    "xyvx9XqV": {
        "id": "xyvx9XqV",
        "title": "Response mechanisms of soil carbon and nitrogen decomposition to temperature change",
        "abstract": "The response of soil carbon and nitrogen decomposition to temperature change is crucial for the impact of climate change on terrestrial ecosystem carbon sink. In this paper, the mechanisms and hypotheses about the effects of temperature change on the decomposition of soil carbon and nitrogen were reviewed. The mechanisms mainly include the functions of the stability, quality, and availability of soil organic matter (SOM), the biomass, activity, community structure, and diversity of soil microbes, the water content in soil, the productivity of vegetation and litter, and the soil pH. There are still uncertainties for the mechanisms about the effects of temperature change on the decomposition of soil carbon and nitrogen, and it is necessary to consider the SOM fractions with different stability, the features of microbes, the interactions between SOM fractions and soil microbial features, and the differences of the long-term and short-term responses of soil carbon and nitrogen decomposition to temperature change. The hypotheses about the effects of temperature change on the decompositioh of soil carbon and nitrogen include carbon quality-temperature hypothesis, physical-chemical hypothesis, and functional shift hypothesis. Further researches and experiments are necessary to test and improve these hypotheses.",
        "keywords": [
            "Climate change",
            "Soil carbon and nitrogen cycle",
            "Temperature change"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            },
            {
                "name": "Lü Jia-jia",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            }
        ],
        "venue": "Chinese Journal of Ecology",
        "year": 2008
    },
    "yMKDUnrb": {
        "id": "yMKDUnrb",
        "title": "Commodification of Discourse in Blogs:An Analysis of \"The First Blog of Public Security of China\"",
        "abstract": "With the rapid development of the Internet,blog has become an important means of communication and an essential way to build up and maintain social relationships.The present paper,through integrating Bhatia's multi-perspective model of discourse analysis and Fairclough's conceptualization of intertextuality,proposes a new model for studying the First Blog of Public Security of China.By applying this model,the paper explores how commodification is realized in the textual and discursive spaces and then reveals the socio-cultural background of commodification.",
        "keywords": [
            "\"The First Blog of Public Security of China\"",
            "commodification of discourse",
            "blog"
        ],
        "authors": [
            {
                "name": "WANG Jing",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou ,Guangdong,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou ,Guangdong,China"
            }
        ],
        "venue": "Journal of South China University of Technology(Social Science Edition)",
        "year": 2012
    },
    "N2STENve": {
        "id": "N2STENve",
        "title": "Effect of lamivudine combined with protocatechuic acid on the distribution of HBV X protein in cellular nucleus",
        "abstract": "OBJECTIVE: To investigate the effect of lamivudine (3TC) combined with protocatechuic acid (PA) on the distribution of HBV X protein in cellular nucleus. METHODS: Huh7 cell was transfected with ectogenic GFP-HBx fused plasmid, and treated by 3TC, PA and 3TC & PA combination respectively the effect of drug treatment on the distribution of HBV X protein (HBx) in Huh7 cell was analyzed by using confocal microscopy. Furthermore, HepG2. 2. 15 cell was treated by 3TC, PA and 3TC & PA combination respectively. The effect of drug treatment on the content of endogenic HBx in cellular nucleus of HepG2. 2. 15 cell was analyzed by Western blot. RESULTS: 3TC and 3TC & PA combination inhibited HBx into cellular nucleus, and the inhibitory action of 3TC & PA combination was more powerful than that of 3TC. CONCLUSION: The inhibitory action of 3TC & PA on HBx may be an important mechanism of action on HBV replication.",
        "keywords": [
            "Hepatitis B virus",
            "Lamivudine",
            "Protocatechuic acid",
            "X protein"
        ],
        "authors": [
            {
                "name": "ZHU Wen-ting",
                "org": "Hubei University(Hubei University,Hubei University of Technology),Wuhan,China"
            },
            {
                "name": "Yong Chen",
                "org": "Hubei University(Hubei University,Hubei University of Technology),Wuhan,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "HAN Feng-mei",
                "org": "Hubei University(Hubei University,Hubei University of Technology),Wuhan,China"
            }
        ],
        "venue": "Chinese Pharmaceutical Journal",
        "year": 2010
    },
    "bZqqeAVP": {
        "id": "bZqqeAVP",
        "title": "Genetic and genotype × environment interaction effects analysis for erucic acid content in rapeseed (<i>Brassica napus L.)</i>",
        "abstract": "Genetic main effects and genotype × environment (GE) interaction effects for erucic acid content (EAC) in rapeseed(Brassica napus L.) were analyzed for two year data by using the genetic models and corresponding statistical approaches for quantitative traits of diploid plant seeds. Eight parents were included in adiallel mating design in two environments. It was found that the embryo, cytoplasmic and maternal main effects and their GE interaction effects could simultaneously affect the performance of EAC, especially for the cytoplasmic and maternal effects. Since the amount of genetic main effects from the expression of genes in different genetic systems accounted for about 64.1%of the total genetic effects, EAC of rapeseed was mainly controlled by genetic main effects. The total narrow-sense heritability for EAC was 83.6% with the general heritability being 51.9% and the interaction heritability being 31.7%. It was suggested by the predicted genetic effects, that Tower and Youcai 601 were better than other parents for reducing EAC in rapeseed quality breeding.",
        "keywords": [
            "erucic acid",
            " genetic effect",
            " heritability",
            " quality",
            " rapeseed (Brassica napus L."
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Haizhen Zhang",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Changtao Li",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Yuling Ren",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Euphytica",
        "year": 2003
    },
    "102T8xBz": {
        "id": "102T8xBz",
        "title": "GP73 Facilitates Hepatitis B Virus Replication by Repressing the NF-κB Signaling Pathway.",
        "abstract": "Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, and 600,000 deaths are caused by HBV-related hepatic failure. Golgi protein 73 (GP73) is a serum biomarker for liver diseases, including chronic hepatitis B (CHB). Here, we determine the effect of HBV infection on GP73 production and characterized the role of GP73 in HBV replication. Initially, we show that GP73 is highly produced in the sera of HBV-positive patients with CLDs and in HBV-stimulated leukocytes. Additionally, HBV stimulation promotes GP73 production in peripheral blood mononuclear cells (PBMCs) isolated from healthy donors and in macrophages derived from human acute monocytic leukemia cells (THP-1). Notably, hepatitis B surface antigen (HBsAg), but not HBV replication, is required for the activation of GP73 expression. Moreover, in HepG2 cells and Huh7 cells, GP73 facilitates HBV replication and represses nuclear factor kappa B p50 (NF-κB p50) expression, which in turn represses HBV replication and GP73 expression. Finally, we demonstrate that GP73 facilitates HBV replication by repressing the innate immune response and the NF-κB signalling pathway. Taken together, we revealed a distinct positive feedback mechanism between HBV replication and GP73 production and suggest that GP73 acts as a potential antiviral target for HBV infection. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "Acute viral infection",
            "Chronic viral infection",
            "Golgi protein 73, GP73",
            "Hepatitis B virus, HBV",
            "Hepatocellular carcinoma, HCC",
            "Nuclear factor kappa B p50, NF-κB p50"
        ],
        "authors": [
            {
                "name": "Long Liu",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jianyong Zhu",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jing Yang",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Xiaohua Li",
                "org": "Department of Emergency, Dongfeng Maojian Hospital, Sinopharm Group Corporation, Shiyan, 442000, China."
            },
            {
                "name": "Jie Yuan",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China."
            },
            {
                "name": "Zhixin Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            }
        ],
        "venue": "Journal of medical virology",
        "year": 2020
    },
    "tJa3efTJ": {
        "id": "tJa3efTJ",
        "title": "Diagnosis and treatment of intestinal necrosis following blunt abdominal trauma:an analysis 11 cases",
        "abstract": "Objective To evaluate the diagnosis and treatment of intestinal necrosis following blunt abdominal trauma.Methods The clinical data of 415 cases of blunt abdominal trauma admitted from January 2000 to January 2008 at Changhai Hospital of the Second Military Medical University were analyzed retrospectively.A total of 11 cases(2.65%)were performed operation to be diagnosed as delayed intestinal necrosis following blunt abdominal trauma.Results A total of 8 cases were underwent partial intestinal or colorectal resection and anastomosis.Three cases were performed enterostomy firstly because of severe abdominal contamination,then performed intestinal or colorectal anastomosis after six months.All the cases were cured,and intestinal fistulas occurred in 2 cases who were then cured by suitable therapy.Conclusion The clinical features of intestinal necrosis following blunt abdominal trauma are rather difficult to be diagnosed correctly in the early stage.CT scan is the most sensitive preoperational examination and reasonable operative procedure is the key to promote the effects of the treatment.",
        "keywords": [
            "blunt abdominal trauma",
            "intestinal necrosis"
        ],
        "authors": [
            {
                "name": "LUO Tian-hang",
                "org": "neral Surgery,Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "LU Zheng-mao",
                "org": "neral Surgery,Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "neral Surgery,Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "f Ge",
                "org": "neral Surgery,Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Practical Surgery",
        "year": 2012
    },
    "Q45qzSmn": {
        "id": "Q45qzSmn",
        "title": "Genetic and genotype x environment interaction effects for the content of seven essential amino acids in indica rice",
        "abstract": "It is necessary for rice breeders to understand the genetic basis of nutrient quality traits of rice. Essential amino acids are most important in determining the nutrient quality of rice grain and can affect the health of people who depend on rice as a staple food. In view of the paucity of genetic information available on essential amino acids in indica rice, we estimated the genetic main effects and genotype x environment (G x E) interaction effects on the content of essential amino acids. Nine cytoplasmic male sterile lines as females and five restorer lines as males were introduced in a North Carolina II design across environments. Estimates of the content of the essential amino acids valine, methionine, leucine and phenylalanine showed that they were mainly controlled by genetic main effects, while the contents of threonine, cysteine and isoleucine were mainly affected by G x E effects. In the case of genetic main effects, both cytoplasmic and maternal genetic effects were predominant for all essential amino acids, indicating that selection for improving essential amino acid content based on maternal performance would be more effective than that based on seeds. The total narrow-sense heritabilities were high and ranged from 0.72 to 0.83. Since general heritabilities for these essential amino acids (except for cysteine) were found to be much larger than G x E interaction heritability, the improvement of content of most essential amino acids under selection would be expected under various environments. Rice varieties such as Zhenan 3, Yinchao 1, T49, 26715, 102 and 1391 should be selected as optimal parents for increasing the content of most essential amino acids, while the total genetic effects from Zhexie 2, Xieqingzao, Gangchao 1, V20, Zuo 5 and Zhenshan 97 were mainly negative and these parents could decrease the contents of most essential amino acids.",
        "keywords": [
            "Essential amino acid",
            "Genetic effect",
            "Genotype x environment interaction",
            "Nutrient quality",
            "Plant breeding",
            "Rice (Oryza sativa L.)"
        ],
        "authors": [
            {
                "name": "jian guo wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Xiaoming Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Tomita Katsura",
                "org": "Fukui Agricultural Experiment Station(Fukui Agric. Experiment Station,Fukui Agricultural Experiment Station),Fukui,Japan"
            }
        ],
        "venue": "Journal of Genetics",
        "year": 2004
    },
    "MckbggvE": {
        "id": "MckbggvE",
        "title": "The Grasslands of Inner Mongolia: A Special Feature",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xingguo Han",
                "org": ""
            },
            {
                "name": "Keith Owens",
                "org": ""
            },
            {
                "name": "X. Ben Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Jianhui Huang",
                "org": ""
            }
        ],
        "venue": "Rangeland Ecology & Management",
        "year": 2009
    },
    "rUe7wElH": {
        "id": "rUe7wElH",
        "title": "Plant species diversity is correlated with climatic factors differently at the community and the functional group levels: A case study of desert steppe in Inner Mongolia, China",
        "abstract": "",
        "keywords": [
            "community",
            "climate",
            "species richness"
        ],
        "authors": [
            {
                "name": "qingyuan zhang",
                "org": ""
            },
            {
                "name": "j wu",
                "org": ""
            },
            {
                "name": "alexander buyantuev",
                "org": ""
            },
            {
                "name": "jinkui niu",
                "org": ""
            },
            {
                "name": "yuhui zhou",
                "org": ""
            },
            {
                "name": "yu ding",
                "org": ""
            },
            {
                "name": "sona kang",
                "org": ""
            },
            {
                "name": "weiya ma",
                "org": ""
            }
        ],
        "venue": "Plant Biosystems",
        "year": 2014
    },
    "acbPjCBV": {
        "id": "acbPjCBV",
        "title": "The ways of upgrading key laboratories in jiangsu medical schools in the new period",
        "abstract": "Many changes have taken place both at home and abroad since the beginning of the new century or the new period which brings a rare opportunity for the construction and development of key laboratories in the schools of higher learning. How to make good use of the new situation so as to realize a development at higher speed is a question deserving much for thought. The article discusses the question and puts forward some suggestions to speed up the construction of key laboratories of Jiangsu medical schools in the hope of providing some useful references for governmental departments concerned as well as for the key laboratories′ own construction.",
        "keywords": [
            "new period key laboratory development ways"
        ],
        "authors": [
            {
                "name": "Liang Hong",
                "org": ", Science and Technology Division of Nanjing Medical University, Nanjing , P.R. China"
            },
            {
                "name": "Lu Jianhua",
                "org": ", Science and Technology Division of Nanjing Medical University, Nanjing , P.R. China"
            },
            {
                "name": "Wu Jianguo",
                "org": ", Science and Technology Division of Nanjing Medical University, Nanjing , P.R. China"
            }
        ],
        "venue": "Jiangsu Healthcare Administration",
        "year": 2007
    },
    "mGQWHU0E": {
        "id": "mGQWHU0E",
        "title": "Inhibition of Hepatitis B virus gene expression by single and dual small interfering RNA treatment.",
        "abstract": "RNA interference (RNAi) has been successfully applied in suppression of Hepatitis B virus (HBV) replication. To circumvent the problem that mutation in HBV genome may result in resistance when siRNA is further developed as an anti-viral drug, in this study, we established a dual small interfering RNA (siRNA) expression system, which could simultaneously express two different siRNA molecules that can specifically target two genes. To test the effectiveness of this system, we applied this new approach to express simultaneously two different 21-bp hairpin siRNA duplexes that specifically attack the HBs and HBx genes of HBV, respectively, in Bel-7402 and HepG2.2.15 cells. Results indicated that dual siRNA could simultaneously inhibit the expression of HBs and HBx gene by 83.7% and 87.5%, respectively, based on luciferase assays. In addition, dual siRNA molecules were able to significantly reduce the amount of HBV core associated DNA, which is considered as an intracellular replicative intermediate, and the viral DNA in culture supernatant. Therefore, this dual siRNA system provides a more powerful tool for the study of gene function and implicates a potential application in the treatment of viral infection.",
        "keywords": [
            "gene expression",
            "dual sirna",
            "hbv",
            "rna interference",
            "small interfering rna"
        ],
        "authors": [
            {
                "name": "Kai-Lang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Xue Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Jianlin Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Yongbo Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Yong-Xin Mu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Mo Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Lu Lu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Virus research",
        "year": 2005
    },
    "CviUmDYE": {
        "id": "CviUmDYE",
        "title": "Addressing rice germplasm genetic potential using genotypic value to develop quality core collections",
        "abstract": "",
        "keywords": [
            "core collection",
            "nir spectroscopy",
            "quality traits",
            "rice",
            "sample proportion",
            "sampling strategy",
            "genetics"
        ],
        "authors": [
            {
                "name": "Chepkurui Kennedy Pkania",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Hai-Ming Xu",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            },
            {
                "name": "Chang-Tao Li",
                "org": ""
            }
        ],
        "venue": "Journal of The Science of Food and Agriculture",
        "year": 2007
    },
    "quaArLib": {
        "id": "quaArLib",
        "title": "In The End Of The Ming Dynasty And The Beginning Of Qing Dynasty The Basic Trend of Narrating Love and Marriage of Imitation Works Of HuaBen",
        "abstract": "Compared to the Love and marriage theme of \"SanYan\",\"ErPai\" is a gifted scholar wrote Love experience,also concerned businessmen and their children,handicrafts and other sectors of the public feelings of the world,\"GuZhangJueChen\" as representatives of these Muiti-chapter ImitativeWorks of Huaben novel draw up the story-telling script novel to concentraten on narrate the talented men and beautiful women mighty waves winding love and marriage story,bold in blazing new trails in such aspects as story space,plot content, characterization,the mode of narrating is changeable,enable its novel scale of medium-length talented men and beautiful women novel while having for the first time.",
        "keywords": [
            "Narration mode",
            "Imitation works of Huaben",
            "Love and marriage theme"
        ],
        "authors": [
            {
                "name": "Zhao Xu",
                "org": "Hunan University of Commerce,Liberal Arts College of Hunan Normal Uniyersity,Changsha,Hunan,"
            },
            {
                "name": "Wu jianguo",
                "org": "Hunan University of Commerce,Liberal Arts College of Hunan Normal Uniyersity,Changsha,Hunan,"
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2007
    },
    "LRIKFP0E": {
        "id": "LRIKFP0E",
        "title": "Type IVB piliated Salmonella typhi enhance IL-6 and NF-κB production in human monocytic THP-1 cells through activation of protein kinase C",
        "abstract": "Salmonella typhi is an important human pathogen responsible for typhoid fever. Type IVB pili, encoded by the S. typhi pil operon located in the major pathogenicity island, are used to facilitate bacterial entry into human intestinal cells in vitro and may be important in the mediation of enteric fever in humans. However, possible involvement of the type IVB pili of S. typhi in signal transduction in infected immune cells has not been examined previously. In this study, we have compared the effect of piliated and nonpiliated S. typhi on the activities of protein kinase C (PKC), the production of interleukin-6 (IL-6) and nuclear transcription factor NF-κB in human monocytic THP-1 cells. We find that piliated S. typhi can stimulate significantly higher activities of PKC, the production of IL-6 and NF-κB than a nonpiliated strain based on substrate phosphorolysis kinase assay, Western blot, RT-PCR, and luciferase reporter gene assay. In time course experiments, PKC activity increased in a time-dependent fashion after stimulation by the piliated bacteria. The PKC inhibitor Dequalinium chloride (DECA) remarkably reduced the production of IL-6, NF-κB and the activity of PKC induced by the piliated S. typhi. These results suggest that the induction of IL-6 and NF-κB depend on the PKC signal pathway. Our report demonstrates that the type IVB pili of S. typhi play important roles in the production of NF-κB and the proinflammatory cytokine IL-6, and in the stimulation of PKC activity and therefore, may have effects on the development of fever and other inflammatory responses. © 2005 Elsevier GmbH. All rights reserved.",
        "keywords": [
            "Il-6",
            "PKC",
            "Salmonella typhi",
            "THP-1 cells",
            "Type IVB pili"
        ],
        "authors": [
            {
                "name": "FuBin Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xiao-Lian Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yan Zhou",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "LinBai Ye",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhongtian Qi",
                "org": "Second Military Medical University(Second Military Medical University),Shanghai,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Immunobiology",
        "year": 2005
    },
    "xjTTyNzY": {
        "id": "xjTTyNzY",
        "title": "Advancing landscape sustainability science: theoretical foundation and synergies with innovations in methodology, design, and application",
        "abstract": "Our society has entered in an era of Anthropocene, in which people and their activities dominate almost all ecosystems on the planet. In the context of growing uncertainties, landscape sustainability science (LSS), as a place-based, use-inspired science, aims to understand and improve the dynamic relationship between ecosystem services and human well-being. In this editorial, we identify the major theoretical foundations of LSS, discuss recent innovations in research methodology to advance LSS, summarize the extension of LSS through landscape design and geo-design, and examine the application of LSS for addressing sustainability challenges across multiple landscapes. We highlight that long-term regional sustainability can only be achieved by integrating context-based sustainability across agricultural, urban, and natural landscapes so as to minimize the regional ecological footprint and make advancement towards achieving the sustainable development goals.",
        "keywords": [
            ""
        ],
        "authors": [
            {
                "name": "Chuan Liao",
                "org": "School of Sustainability, Arizona State University, Tempe, USA"
            },
            {
                "name": "Jiangxiao Qiu",
                "org": "School of Forest Resources & Conservation, University of Florida, Davie, USA"
            },
            {
                "name": "Bin Chen",
                "org": "School of Environment, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Deliang Chen",
                "org": "Department of Earth Sciences, University of Gothenburg, Gothenburg, Sweden"
            },
            {
                "name": "Bojie Fu",
                "org": "State Kay Lab of Urban and Regional Ecology, Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning, Arizona State University, Tempe, USA"
            },
            {
                "name": "Chunyang He",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "G. Darrel Jenerette",
                "org": "Department of Botany and Plant Sciences, University of California-Riverside, Riverside, USA"
            },
            {
                "name": "Xia Li",
                "org": "School of Geographic Sciences, East China Normal University, Shanghai, China"
            },
            {
                "name": "Xiaoyan Li",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Xin Li",
                "org": "Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Bading Qiuying",
                "org": "School of Geographic Sciences, Qinghai Normal University, Xining, China"
            },
            {
                "name": "Peijun Shi",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2020
    },
    "MZ3lmYvp": {
        "id": "MZ3lmYvp",
        "title": "Study on the global and local calibration methods of tryptophan content in rice by near infrared reflectance spectroscopy",
        "abstract": "Tryptophan is one of the essential amino acids in human, and also considered as an important limiting amino acid in rice. Alkali hydrolysis method was used to determine the tryptophan content of 272 representative samples selected from the 1 256 samples in four years. Based on the milled rice flour spectroscopy, by comparing the prediction abilities of the equations with global calibrations and local calibration, the global calibration method with MPLS and the local calibration method were better than others. Their calibration models could be introduced to application because of low standard errors of prediction for both methods (0.007%) and high coefficients of determination (87.1% and 87.4%, respectively). Furthermore, the prediction ability of the equation based on the brown rice spectroscopy could be still used for determination application though their effects were worse than that of the milled rice flour spectroscopy. It was concluded that the equation could be directly used to estimate the content of tryptophan in milled rice, and the technology of near infrared reflectance spectroscopy developed in this study could be applied in selecting breeding materials for higher tryptophan content and in quality control during rice processing.",
        "keywords": [
            "Global calibration",
            "Local calibration",
            "Milled rice",
            "Near infrared reflectance spectroscopy (NIRS)",
            "Tryptophan content"
        ],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Da-Peng Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Wen-Bin Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ke-Min Wang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Guan Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ya-Zhen Yao",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chun-Hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2011
    },
    "dNsVRJad": {
        "id": "dNsVRJad",
        "title": "Type IVB pilus operon promoter controlling expression of the severe acute respiratory syndrome-associated coronavirus nucleocapsid gene in Salmonella enterica Serovar Typhi elicits full immune response by intranasal vaccination.",
        "abstract": "Attenuated Salmonella enterica serovar Typhi strains have been considered to be attractive as potential live oral delivery vector vaccines because of their ability to elicit the full array of immune responses in humans. In this study, we constructed an attenuated S. enterica serovar Typhi strain stably expressing conserved nucleocapsid (N) protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) by integrating the N gene into the pilV gene, which was under the control of the type IVB pilus operon promoter in S. enterica serovar Typhi. BALB/c mice were immunized with this recombinant strain through different routes: intranasally, orogastrically, intraperitoneally, and intravenously. Results showed that the intranasal route caused the highest production of specific immunoglobulin G (IgG), IgG2a, and secretory IgA, where IgG2a was imprinted as a Th1 cell bias. Moreover, this recombinant live vaccine induced significantly high levels of specific cytotoxic T-lymphocyte activities and increased gamma interferon-producing T cells compared with the parental strain. Our work provides insights into how the type IVB pilus operon promoter controlling SARS-CoV N gene expression in Salmonella might be attractive for a live-vector vaccine against SRAS-CoV infection, for it could induce mucosal, humoral, and cellular immune responses. Our work also indicates that the type IVB pilus operon promoter controlling foreign gene expression in Salmonella can elicit full immune responses by intranasal vaccination.",
        "keywords": [
            "operon",
            "immune response",
            "cytotoxic t lymphocyte",
            "gene expression",
            "vaccination"
        ],
        "authors": [
            {
                "name": "Fengling Luo",
                "org": ""
            },
            {
                "name": "Yong Feng",
                "org": ""
            },
            {
                "name": "Min Liu",
                "org": ""
            },
            {
                "name": "Pingfei Li",
                "org": ""
            },
            {
                "name": "Qin Pan",
                "org": ""
            },
            {
                "name": "Victor Tunje Jeza",
                "org": ""
            },
            {
                "name": "Bing Xia",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Xiao-Lian Zhang",
                "org": ""
            }
        ],
        "venue": "Clinical and vaccine immunology : CVI",
        "year": 2007
    },
    "8iLmqj5J": {
        "id": "8iLmqj5J",
        "title": "Promotion of tuition quality in Genetics by developing an excellent instructional system]",
        "abstract": "This article, which is based on the requirements for developing the course of Genetics as an outstanding course, summarizes the experience of engendering an excellent instructional system, expatiates on the effects of its application to the teaching process of \"Genetics\" and next step work for continuing this instructional system. The course quality of \"Genetics\" has been improved under the excellent instructional system by including different teaching methods, renovating the teaching contents, innovating the teaching means, developing a practical courseware, writing extractive textbooks, reforming experimental teaching, and constructing an instructional network, together with teaching methods related to scientific research.",
        "keywords": [
            "genetics",
            "teaching effect",
            "construction of course",
            "teaching of undergraduate course",
            "creation ability"
        ],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Jian-Fu Xiao",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2013
    },
    "OVzaJTSR": {
        "id": "OVzaJTSR",
        "title": "China's response to a national land-system sustainability emergency",
        "abstract": "China has responded to a national land-system sustainability emergency via an integrated portfolio of large-scale programmes. Here we review 16 sustainability programmes, which invested US$378.5 billion (in 2015 US$), covered 623.9 million hectares of land and involved over 500 million people, mostly since 1998. We find overwhelmingly that the interventions improved the sustainability of China’s rural land systems, but the impacts are nuanced and adverse outcomes have occurred. We identify some key characteristics of programme success, potential risks to their durability, and future research needs. We suggest directions for China and other nations as they progress towards the Sustainable Development Goals of the United Nations’ Agenda 2030.",
        "keywords": "",
        "authors": [
            {
                "name": "Brett A. Bryan",
                "org": "Centre for Integrative Ecology, Deakin University, Geelong, Australia"
            },
            {
                "name": "Brett A. Bryan",
                "org": "Centre for Integrative Ecology, Deakin University, Geelong, Australia"
            },
            {
                "name": "Lei Gao",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Yangqiong Ye",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Yangqiong Ye",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Xiufeng Sun",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Xiufeng Sun",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Jeffery D. Connor",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Jeffery D. Connor",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Neville D. Crossman",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Neville D. Crossman",
                "org": "CSIRO, Waite Campus, Adelaide, Australia"
            },
            {
                "name": "Mark Stafford-Smith",
                "org": "CSIRO, Black Mountain, Canberra, Australia"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Deyong Yu",
                "org": ""
            },
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Ang Li",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Qingxu Huang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Hai Ren",
                "org": ""
            },
            {
                "name": "Xiangxheng Deng",
                "org": "Center for Chinese Agricultural Policy, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Hua Zheng",
                "org": "State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China"
            },
            {
                "name": "Jianming Niu",
                "org": ""
            },
            {
                "name": "Guodong Han",
                "org": ""
            },
            {
                "name": "Xiangyang Hou",
                "org": "National Forage Improvement Center, Key Laboratory of Grassland Resources and Utilization of Ministry of Agriculture, Institute of Grassland Research, Chinese Academy of Agricultural Sciences, Hohhot, China"
            }
        ],
        "venue": "Nature",
        "year": 2018
    },
    "hdTc4Lmb": {
        "id": "hdTc4Lmb",
        "title": "Rice Dwarf Virus P2 Protein Hijacks Auxin Signaling by Directly Targeting the Rice OsIAA10 Protein, Enhancing Viral Infection and Disease Development.",
        "abstract": "The phytohormone auxin plays critical roles in regulating myriads of plant growth and developmental processes. Microbe infection can disturb auxin signaling resulting in defects in these processes, but the underlying mechanisms are poorly understood. Auxin signaling begins with perception of auxin by a transient co-receptor complex consisting of an F-box transport inhibitor response 1/auxin signaling F-box (TIR1/AFB) protein and an auxin/indole-3-acetic acid (Aux/IAA) protein. Auxin binding to the co-receptor triggers ubiquitination and 26S proteasome degradation of the Aux/IAA proteins, leading to subsequent events, including expression of auxin-responsive genes. Here we report that Rice dwarf virus (RDV), a devastating pathogen of rice, causes disease symptoms including dwarfing, increased tiller number and short crown roots in infected rice as a result of reduced sensitivity to auxin signaling. The RDV capsid protein P2 binds OsIAA10, blocking the interaction between OsIAA10 and OsTIR1 and inhibiting 26S proteasome-mediated OsIAA10 degradation. Transgenic rice plants overexpressing wild-type or a dominant-negative (degradation-resistant) mutant of OsIAA10 phenocopy RDV symptoms are more susceptible to RDV infection; however, knockdown of OsIAA10 enhances the resistance of rice to RDV infection. Our findings reveal a previously unknown mechanism of viral protein reprogramming of a key step in auxin signaling initiation that enhances viral infection and pathogenesis.",
        "keywords": "",
        "authors": [
            {
                "name": "Lian Jin",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Qingqing Qin",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Yu Wang",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Yingying Pu",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Lifang Liu",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Xing Wen",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Shaoyi Ji",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Jianguo Wu",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Chunhong Wei",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            },
            {
                "name": "Biao Ding",
                "org": "Department of Molecular Genetics and Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America."
            },
            {
                "name": "Yi Li",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, People's Republic of China."
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2016
    },
    "naVXwsYP": {
        "id": "naVXwsYP",
        "title": "The Current Research Status of Foamed Magnesium Alloy",
        "abstract": "This paper reviews several preparation methods of foamed magnesium and analyses the principles,processes,advantages and limitations between these methods.It also analyses the compression and bionic properties of foamed magnesium alloy.Finally,it makes prospects of mechanization in foamed magnesium alloy production.",
        "keywords": [
            "foamed magnesium alloy",
            "foamed metal",
            "bionic property",
            "fabrication method",
            "compression property"
        ],
        "authors": [
            {
                "name": "XU Meng-xin",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Lu-cai",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Fang",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "YOU Xiao-hong",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            }
        ],
        "venue": "Foundry Equipment and Technology",
        "year": 2010
    },
    "TjrpkQOp": {
        "id": "TjrpkQOp",
        "title": "Enterovirus 71 Represses Interleukin Enhancer-Binding Factor 2 Production and Nucleus Translocation to Antagonize ILF2 Antiviral Effects.",
        "abstract": "Enterovirus 71 (EV71) infection causes hand-foot-mouth disease (HFMD), meningoencephalitis, neonatal sepsis, and even fatal encephalitis in children, thereby presenting a serious risk to public health. It is important to determine the mechanisms underlying the regulation of EV71 infection. In this study, we initially show that the interleukin enhancer-binding factor 2 (ILF2) reduces EV71 50% tissue culture infective dose (TCID50) and attenuates EV71 plaque-formation unit (PFU), thereby repressing EV71 infection. Microarray data analyses show that ILF2 mRNA is reduced upon EV71 infection. Cellular studies indicate that EV71 infection represses ILF2 mRNA expression and protein production in human leukemic monocytes (THP-1) -differentiated macrophages and human rhabdomyosarcoma (RD) cells. In addition, EV71 nonstructural protein 2B interacts with ILF2 in human embryonic kidney (HEK293T) cells. Interestingly, in the presence of EV71 2B, ILF2 is translocated from the nucleus to the cytoplasm, and it colocalizes with 2B in the cytoplasm. Therefore, we present a distinct mechanism by which EV71 antagonizes ILF2-mediated antiviral effects by inhibiting ILF2 expression and promoting ILF2 translocation from the nucleus to the cytoplasm through its 2B protein.",
        "keywords": [
            "EV71",
            "EV71 nonstructural protein 2B",
            "ILF2",
            "enterovirus 71",
            "interleukin enhancer-binding factor 2",
            "virus infection",
            "virus replication"
        ],
        "authors": [
            {
                "name": "Jing Jin",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Sha Ai",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yu Song",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Zhen Luo",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            }
        ],
        "venue": "Viruses",
        "year": 2019
    },
    "DWHcpEwQ": {
        "id": "DWHcpEwQ",
        "title": "The RDV P2 protein interacts with OsIAA10.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jin Lian",
                "org": ""
            },
            {
                "name": "Qin Qingqing",
                "org": ""
            },
            {
                "name": "Wang Yu",
                "org": ""
            },
            {
                "name": "Pu Yingying",
                "org": ""
            },
            {
                "name": "Liu Lifang",
                "org": ""
            },
            {
                "name": "Wen Xing",
                "org": ""
            },
            {
                "name": "Ji Shaoyi",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            },
            {
                "name": "Wei Chunhong",
                "org": ""
            },
            {
                "name": "Ding Biao",
                "org": ""
            },
            {
                "name": "Li Yi",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2016
    },
    "ajd4bsG0": {
        "id": "ajd4bsG0",
        "title": "Research and Practice of the Cultivating Modes for Mechatronics Majors through Co-op Education",
        "abstract": "Co-op education is a set policy on developing the higher vocational education in China.In this paper,the cultivating modes for mechatronics majors through education with industry and scientific research are researched and practised by positioning the majors cultivating target,reforming the teaching system,renewing the teaching content,improving the student’s basic qualities,constructing the team of “instructor & engineer” teachers.",
        "keywords": [
            "co-op education",
            "higher vocational education",
            "modes of cultivating"
        ],
        "authors": [
            {
                "name": "WANG Yan-hui",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "WANG Wen-hong",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "YI Shun-ming",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2007
    },
    "FYAM0mjh": {
        "id": "FYAM0mjh",
        "title": "High-throughput screen of protein expression levels induced by cyclooxygenase-2 during influenza a virus infection.",
        "abstract": "Detection of proteins productions and the functions during the influenza A virus infection, especially the proteins expression levels in the patients serum are emphasized in the research of host immune response to influenza virus infection. Protein microarray technology provides a high-throughput platform for efficient profiling of protein expression.We investigated the expression levels of 507 immune-related proteins in the 85 serum of patients infected by influenza A virus H3N2 using an antibody array and validated these findings by infecting peripheral blood mononuclear cells (PBMCs) with A/HongKong/498/97 (H3N2) in vitro. Then we used selective inhibitor of proinflammatory factor cyclooxygenase-2 (COX-2) NS-398 to identify those immunomodulatory proteins regulated by the proinflammatory factor.In patients' serum, the expression levels of 138 proteins changed >2-fold in response to viral infection, including 102 that were upregulated and 36 that were downregulated. One-hundred six proteins were confirmed in PBMCs infected by H3N2. Of the 106 proteins involved in the immune response to influenza virus infection, 48 were regulated by COX-2.Our findings identify the host proteins whose expression levels change in response to influenza virus infection and those involved in the proinflammatory factor COX-2-mediated inflammatory cascade.",
        "keywords": [
            "cyclooxygenase-2",
            "protein antibody array",
            "influenza a virus",
            "high throughput screening",
            "immune response",
            "high throughput",
            "protein expression"
        ],
        "authors": [
            {
                "name": "Li Liu",
                "org": ""
            },
            {
                "name": "Rui Li",
                "org": ""
            },
            {
                "name": "Ying Pan",
                "org": ""
            },
            {
                "name": "Jing Chen",
                "org": ""
            },
            {
                "name": "Yongkui Li",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            }
        ],
        "venue": "Clinica chimica acta; international journal of clinical chemistry",
        "year": 2011
    },
    "qhRSrR4C": {
        "id": "qhRSrR4C",
        "title": "Stimulatory effect of LPS and feedback effect of PGE2 on IL-27 production",
        "abstract": "Interleukin (IL)-27 is a new member of the IL-6/IL-12 family, composed of two subunits, the Epstein-Barr virus-induced gene 3 (EBI3) and p28 chains (p28), and produced by activated monocytes and dendritic cells. IL-27 plays an important role in the regulation of differentiation of naive T helper cells and has diverse effects on innate immune cells. However, the pro-inflammatory mechanisms of IL-27 are still not well known. In this study, we investigated the effect of lipopolysaccharide (LPS) on the production of IL-27. We found that LPS-stimulated IL-27 production was in a dose-dependent and time-dependent manner in THP-1 cells. We have also shown that IL-27 induced PGE2 production and COX-2 gene expression at the level of mRNA as well as protein. Moreover, we found feed back effect of PGE2 on the production of IL-27 in THP-1 cells. The results suggest that PGE2 significantly inhibits LPS-induced IL-27 production, without affecting basal IL-27 expression. Further experiment suggests that PGE2 and LPS regulate IL-27 through NF-κB pathway. Our findings may have wide implication for IL-27 in inflammatory diseases. © 2010 The Authors. Scandinavian Journal of Immunology © 2010 Blackwell Publishing Ltd.",
        "keywords": [],
        "authors": [
            {
                "name": "Chengliang Zhu",
                "org": "Hubei General Hospital(Wuhan University,Renmin Hospital of Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanhua Cao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Rui Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yunchun Song",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Feng Pan",
                "org": "Hubei General Hospital(Wuhan University,Renmin Hospital of Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanhong Li",
                "org": "Hubei General Hospital(Wuhan University,Renmin Hospital of Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fang Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Scandinavian Journal of Immunology",
        "year": 2010
    },
    "4MnQj8gD": {
        "id": "4MnQj8gD",
        "title": "Rice Stripe Mosaic Virus-encoded P4 Is A Weak Suppressor of Viral RNA Silencing and is Required for Disease Symptom Development.",
        "abstract": "Viral suppressors of RNA silencing (VSRs) are a cluster of viral proteins that have evolved to counteract eukaryotic antiviral RNA silencing pathways, thereby contributing to viral pathogenicity. In this study, we revealed that the matrix protein P4 encoded by Rice stripe mosaic virus (RSMV), which is an emerging cytoplasmic rhabdovirus, is a weak RNA silencing suppressor. By conducting yeast two-hybrid, bimolecular fluorescence complementation, and subcellular co-localization assays, we proved that P4 interacts with the rice endogenous suppressor of gene silencing 3 (OsSGS3). We also determined that P4 overexpression has no effect on OsSGS3 transcription. However, P4 can promote the degradation of OsSGS3 via ubiquitination and autophagy. Additionally, a Potato virus X-based expression system was used to confirm that P4 enhances the development of mosaic symptoms on Nicotiana benthamiana leaves by promoting hydrogen peroxide accumulation, but not cell death. To verify whether P4 is a pathogenicity factor in host plants, we generated transgenic P4-overexpressing rice plants, which exhibited disease-related developmental defects, including decreased plant height and excessive tillering. Our data suggest that RSMV-encoded P4 serves as a weak VSR that inhibits antiviral RNA silencing by targeting OsSGS3.",
        "keywords": "",
        "authors": [
            {
                "name": "Chao Zhang",
                "org": "Vector-borne Virus Research Center, Fujian Agriculture and Forestry University, Fuzhou, China; chaozhang21@126.com."
            },
            {
                "name": "Dong Chen",
                "org": "Vector-borne Virus Research Center, Fuzhou, China; chendong199509@163.com."
            },
            {
                "name": "Guoyi Yang",
                "org": "Vector-borne Virus Research Center, Fuzhou, China; 495718283@QQ.COM."
            },
            {
                "name": "Xiyuan Yu",
                "org": "Vector-borne Virus Research Center, Fuzhou, China; Yuxiyuan9826@163.com."
            },
            {
                "name": "Jianguo Wu",
                "org": "Vector-borne Virus Research Center, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China, 350002; wujianguo81@126.com."
            }
        ],
        "venue": "Molecular plant-microbe interactions : MPMI",
        "year": 2019
    },
    "RaJDyidB": {
        "id": "RaJDyidB",
        "title": "Timing of gene expression from different genetic systems in shaping leucine and isoleucine contents of rapeseed (Brassica napus L.) meal.",
        "abstract": "Experiments were conducted on rapeseed (Brassica napus L.) using a diallel design with nine parents: Youcai 601, Double 20-4, Huashuang 3, Gaoyou 605, Zhongyou 821, Eyouchangjia, Zhong R-888, Tower and Zheshuang 72. The seed developmental process was divided into five stages, namely initial (days 1-15 after flowering), early (days 16-22 after flowering), middle (days 23-29), late (days 30-36), and maturing (days 37-43) developmental stages. The variation of dynamic genetic effects for leucine and isoleucine contents of rapeseed meal was analysed at five developmental stages, across different environments using the genetic models with time-dependent measures. The results from unconditional and conditional analyses indicated that the expression of diploid embryo, cytoplasmic and diploid maternal plant genes were important for leucine and isoleucine contents at different developmental stages of rapeseed, particularly at the initial and early developmental stages. Among different genetic systems, nutrition quality traits were mainly controlled by the accumulative or net maternal main effects and their GE interaction effects, except at maturity when the net diploid embryo effects were larger. The expression of genes was affected by the environmental conditions on 15, 22, 29 or 36 days after flowering, but was more stable at mature stage. For the isoleucine content the narrow-sense heritabilities on 15, 22, 29, 36, and 43 days after flowering were 43.0, 65.7, 60.1, 65.5 and 78.2%, respectively, while for the leucine content the corresponding narrow-sense heritabilities were relatively smaller. The interaction heritabilities were more important than the general heritabilities at the first three developmental times. The improvement for isoleucine content could be achieved by selection based on the higher narrow-sense heritabilities. Various genetic systems exhibited genetic correlations among the developmental times or leucine and isoleucine contents. A simultaneous improvement of leucine and isoleucine contents seems possible because of the significant positive genetic correlation components from different genetic systems at different developmental times.",
        "keywords": [
            "genetic variances",
            "conditional genetic variances",
            "rapeseed meal",
            "genetic correlations",
            "leucine content",
            "isoleucine content",
            "developmental genetics",
            "heritability"
        ],
        "authors": [
            {
                "name": "Guolin Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "jian guo wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Murali-Tottekkaad Variath",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of genetics",
        "year": 2011
    },
    "gW4DDb1Q": {
        "id": "gW4DDb1Q",
        "title": "Infection of mice, ferrets, and rhesus macaques with a clinical mumps virus isolate.",
        "abstract": "In recent years, many mumps outbreaks have occurred in vaccinated populations worldwide. The reasons for these outbreaks are not clear. Animal models are needed to investigate the causes of outbreaks and to understand the pathogenesis of mumps virus (MuV). In this study, we have examined the infection of three animal models with an isolate of mumps virus from a recent outbreak (MuV-IA). We have found that while both ferrets and mice generated humoral and cellular immune responses to MuV-IA infection, no obvious signs of illness were observed in these animals; rhesus macaques were the most susceptible to MuV-IA infection. Infection of rhesus macaques via both intranasal and intratracheal routes with MuV-IA led to the typical clinical signs of mumps 2 weeks to 4 weeks postinfection. However, none of the infected macaques showed any fever or neurologic signs during the experimental period. Mumps viral antigen was detected in parotid glands by immunohistochemistry (IHC). Rhesus macaques represent the best animal model for the study of mumps virus pathogenesis.",
        "keywords": [
            "real time polymerase chain reaction",
            "immunohistochemistry",
            "vero cells"
        ],
        "authors": [
            {
                "name": "Pei Xu",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Zhixiang Huang",
                "org": "Wuhan University, School of Medicine(),Wuhan,China"
            },
            {
                "name": "Xiudan Gao",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Frank J Michel",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Gwen Hirsch",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Robert J Hogan",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Kaori Sakamoto",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Wenzhe Ho",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Biao He",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            }
        ],
        "venue": "Journal of virology",
        "year": 2013
    },
    "MkIgwahF": {
        "id": "MkIgwahF",
        "title": "Towards Quantitatively Understanding the Complexity of Social-Ecological Systems—From Connection to Consilience",
        "abstract": "The complexity of social-ecological systems (SES) is rooted in the outcomes of node activities connected by network topology. Thus far, in network dynamics research, the connectivity degree (CND), indicating how many nodes are connected to a given node, has been the dominant concept. However, connectivity focuses only on network topology, neglecting the crucial relation to node activities, and thereby leaving system outcomes largely unexplained. Inspired by the phenomenon of “consensus of wills and coordination of activities” often observed in disaster risk management, we propose a new concept of network characteristic, the consilience degree (CSD), aiming to measure the way in which network topology and node activities together contribute to system outcomes. The CSD captures the fact that nodes may assume different states that make their activities more or less compatible. Connecting two nodes with in/compatible states will lead to outcomes that are un/desirable from the perspective of the SES in question. We mathematically prove that the CSD is a generalized CND, and the CND is a special case of CSD. As a general, fundamental concept, the CSD can facilitate the development of a new framework of network properties, models, and theories that allows us to understand patterns of network behavior that cannot be explained in terms of connectivity alone. We further demonstrate that a co-evolutionary mechanism can naturally improve the CSD. Given the generality of co-evolution in SES, we argue that the CSD is an inherent attribute rather than an artificial concept, which underpins the fundamental importance of the CSD to the study of SES.",
        "keywords": [
            "Complex networks",
            " Consilience degree",
            " Co-evolution",
            " Disaster risk reduction",
            " Social-ecological systems"
        ],
        "authors": [
            {
                "name": "Xiao-Bing Hu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Peijun Shi",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Ming Wang",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Tao Ye",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Mark S. Leeson",
                "org": "School of Engineering,University of Warwick,Coventry,UK"
            },
            {
                "name": "Sander E. van der Leeuw",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Ortwin Renn",
                "org": "Stuttgart Research Center for Interdisciplinary Risk and Innovation Studies,University of Stuttgart,Stuttgart,Germany"
            },
            {
                "name": "Carlo Jaeger",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            }
        ],
        "venue": "International Journal of Disaster Risk Science",
        "year": 2017
    },
    "14bglubx": {
        "id": "14bglubx",
        "title": "Spatial heterogeneity of urban soils: the case of the Beijing metropolitan region, China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qizheng mao",
                "org": "beijing normal university"
            },
            {
                "name": "ganlin huang",
                "org": "beijing normal university"
            },
            {
                "name": "alexander buyantuev",
                "org": "university at albany suny"
            },
            {
                "name": "jianguo wu",
                "org": "beijing normal university"
            },
            {
                "name": "shanghua luo",
                "org": ""
            },
            {
                "name": "keming ma",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "",
        "year": 2014
    },
    "Cem15Rem": {
        "id": "Cem15Rem",
        "title": "Studies on mineral nutrition and safety of wild rice (Oryza L.).",
        "abstract": "Mineral element contents of five wild rice were analyzed, including mineral nutrient elements such as phosphorus (P), potassium (K), calcium (Ca), sodium (Na), magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu), manganese (Mn) and selenium (Se), and the potential toxic elements arsenic (As), mercury (Hg), lead (Pb) and cadmium (Cd). The results showed that the contents of K, Mg, Fe, Zn, Cu, Mn and Se in five wild rice materials were much higher than the cultivate variety Zhou 903 in both brown and milled rice. Wild rice also had lower potential toxic element contents of Hg, Pb and Cd compared with Zhou 903 in brown rice and milled rice, respectively. Among five wild rice samples, WR-3 from Uganda had the highest level of P, K, Ca, Na, Mg, Fe, Zn, Mn and Se, and the lowest contents of Hg, Pb and Cd.",
        "keywords": [
            "potential toxic elements",
            "milled rice",
            "brown rice",
            "wild rice",
            "mineral nutrition"
        ],
        "authors": [
            {
                "name": "Shuli Jiang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "International journal of food sciences and nutrition",
        "year": 2009
    },
    "oBymFGG1": {
        "id": "oBymFGG1",
        "title": "Morphogenesis and molecular basis on naked seed rice, a novel homeotic mutation of OsMADS1 regulating transcript level of AP3 homologue in rice.",
        "abstract": "The floral organs are formed from floral meristem with a regular initiation pattern in angiosperm species. Flowers of naked seed rice (nsr) were characterized by the overdeveloped lemma and palea, the transformation of lodicules to palea-/lemma-like organs, the\n decreased number of stamens and occasionally extra pistils. Some nsr spikelets contained additional floral organs of four whorls and/or abnormal internal florets. The floral primordium of nsr spikelet is differentiated under an irregular pattern and an incomplete determination. And molecular analysis indicated that\n nsr was a novel homeotic mutation in OsMADS1, suggesting that OsMADS1 played a distinct role in regulating the differentiation pattern of floral primordium and in conferring the determination\n of flower meristem. The gain-of-function of OsMADS1 transgenic lines presented the transformation of outer glumes to lemma-/palea-like organs and no changes in length of lemma\n and palea, but loss-of-function of OsMADS1 transgenic lines displayed the overdeveloped lemma and palea. Both findings revealed that OsMADS1 played a role in specifying lemma and palea and acted as a repressor of overdevelopment of lemma and palea. Moreover, it\n was indicated that OsMADS1 upregulated the transcript level of AP3 homologue OsMADS16, using real-time PCR analysis on gain- and loss-of-function of OsMADS1 transgenic lines.",
        "keywords": [
            "flower development",
            "mads-box",
            "naked seed rice",
            "rice",
            "scanning electron microscopy",
            "real time pcr"
        ],
        "authors": [
            {
                "name": "Zhi-Xiong Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Wo-Na Ding",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Han-Ming Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ping Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chun-Hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Planta",
        "year": 2006
    },
    "u9p9cxDL": {
        "id": "u9p9cxDL",
        "title": "Study on the control system of the hoop standard granulator based on the expert system",
        "abstract": "According to analyze the structure and technology of the hoop standard granulator,and obtain the energy consumption calculation formula,and comes to the conclusion that the hoop standard granulator is a multivariate system with large time delays,and this system is also uncertain and nonlinear.Aiming at the problem that hoop standard granulator can't be controlled well by traditional methods.The author creatively designed a technique based on controlling the hoop standard granulator automatically by the expert system and the corresponding control strategy as well.In order to verify the design,some experiments were carried out under the situation of disturbance.Finally the effect of expert control system is validated by simulation.",
        "keywords": [
            "expert system",
            "hoop standard granuiator",
            "large time delays",
            "nonlinear"
        ],
        "authors": [
            {
                "name": "Zhang Kun",
                "org": "School of Mechatronic Engineering & Automation,Shanghai University,Shanghai,,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "School of Electrical Engineering of Nantong University,Nantong,,Jiangsu,China"
            },
            {
                "name": "Zhang Peijian",
                "org": "School of Electrical Engineering of Nantong University,Nantong,,Jiangsu,China"
            },
            {
                "name": "Hu Zhijiang",
                "org": "School of Electrical Engineering of Nantong University,Nantong,,Jiangsu,China"
            }
        ],
        "venue": "Computers and Applied Chemistry",
        "year": 2012
    },
    "iSpcOjmW": {
        "id": "iSpcOjmW",
        "title": "Preparation,component analysis and function evaluation of sweet potato dietary fiber beverage",
        "abstract": "The paper optimized the prescription of fermentation broth coming from sweet potato residue fermented by officinal fungus,and estimated the component and function of the product. After preparation,the optimization prescription was obtained:fermentation broth dilute four times,8mg/L neotame,0.8g/L baking sweet potato essence,0.5g/L citric acid. After component analysis of product,it was found that the preproduction riched in dietary fiber,protein and amino acid,and lacked of fat and sugar. After function evaluation of product,it was approved that the product could promote peristalsis of rat small intestine,so the product could prevent and cure astriction.",
        "keywords": [
            "sweet potato residue",
            "dietary fiber",
            "optimization",
            "function"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZHOU Shuai",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZENG Fu-guang",
                "org": " Jianshi Sanyou Potato Industry Development Co.,Ltd.,Enshi ,China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Science and Technology of Food Industry",
        "year": 2010
    },
    "sMU8OrX7": {
        "id": "sMU8OrX7",
        "title": "Substantial impacts of landscape changes on summer climate with major regional differences: The case of China.",
        "abstract": "China's rapid socioeconomic development during the past few decades has resulted in large-scale landscape changes across the country. However, the impacts of these land surface modifications on climate are yet to be adequately understood. Using a coupled process-based land-atmospheric model, therefore, we quantified the climatic effects of land cover and land management changes over mainland China from 2001 to 2010, via incorporation of real-time and high-quality satellite-derived landscape representation (i.e., vegetation fraction, leaf area index, and albedo) into numerical modeling. Our results show that differences in landscape patterns due to changes in land cover and land management have exerted a strong influence on summer climate in China. During 2001 and 2010, extensive cooling of up to 1.5°C was found in the Loess Plateau and 1.0°C in northeastern China. In contrast, regional-scale warming was detected in the Tibetan Plateau (0.3°C), Yunnan province (0.4°C), and rapidly expanding urban centers across China (as high as 2°C). Summer precipitation decreased in the northeastern region, with patchy reduction generally <1.8mm/day, but increased in the Loess Plateau, with local spikes up to 2.4mm/day. Our study highlights that human alterations of landscapes have had substantial impacts on summer climate over the entire mainland China, but these impacts varied greatly on the regional scale, including changes in opposite directions. Therefore, effective national-level policies and regional land management strategies for climate change mitigation and adaptation should take explicit account of the spatial heterogeneity of landscape-climate interactions.",
        "keywords": [
            "Climate change",
            "Land cover change",
            "Land management change",
            "Land surface biophysical property",
            "WRF"
        ],
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning, Urban Climate Research Center, Arizona State University, Tempe, AZ 85287, United States."
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China; School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ 85287, United States."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2017
    },
    "vAovlWiX": {
        "id": "vAovlWiX",
        "title": "Rice stripe tenuivirus p2 may recruit or manipulate nucleolar functions through an interaction with fibrillarin to promote virus systemic movement.",
        "abstract": "Rice stripe virus (RSV) is the type species of the genus Tenuivirus and represents a major viral pathogen affecting rice production in East Asia. In this study, RSV p2 was fused to yellow fluorescent protein (p2-YFP) and expressed in epidermal cells of Nicotiana benthamiana. p2-YFP fluorescence was found to move to the nucleolus initially, but to leave the nucleolus for the cytoplasm forming numerous distinct bright spots there at later time points. A bimolecular fluorescence complementation (BiFC) assay showed that p2 interacted with fibrillarin and that the interaction occurred in the nucleus. Both the nucleolar localization and cytoplasmic distribution of p2-YFP fluorescence were affected in fibrillarin-silenced N. benthamiana. Fibrillarin depletion abolished the systemic movement of RSV, but not that of Tobacco mosaic virus (TMV) and Potato virus X (PVX). A Tobacco rattle virus (TRV)-based virus-induced gene silencing (VIGS) method was used to diminish RSV NS2 (encoding p2) or NS3 (encoding p3) during RSV infection. Silencing of NS3 alleviated symptom severity and reduced RSV accumulation, but had no obvious effects on virus movement and the timing of symptom development. However, silencing of NS2 abolished the systemic movement of RSV. The possibility that RSV p2 may recruit or manipulate nucleolar functions to promote virus systemic infection is discussed.",
        "keywords": [
            "rice stripe virus",
            "fibrillarin",
            "nucleolus",
            "systemic movement"
        ],
        "authors": [
            {
                "name": "Luping Zheng",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, 350002, China."
            },
            {
                "name": "Zhenguo Du",
                "org": ""
            },
            {
                "name": "Chen Lin",
                "org": ""
            },
            {
                "name": "Qianzhuo Mao",
                "org": ""
            },
            {
                "name": "Kangcheng Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Taiyun Wei",
                "org": ""
            },
            {
                "name": "Zujian Wu",
                "org": ""
            },
            {
                "name": "Lianhui Xie",
                "org": ""
            }
        ],
        "venue": "Molecular plant pathology",
        "year": 2014
    },
    "G8vZJwns": {
        "id": "G8vZJwns",
        "title": "Genetic analysis for oil and protein contents of rapeseed (Brassica napus L.) at different developmental times",
        "abstract": "The dynamic expression of genes for oil and protein contents of rapeseed (Brassica napus L.) was carried out with time-dependent measures by using the developmental genetic models for quantitative traits in diploid plant. The unconditional and conditional analysis showed that the accumulated genetic effects or net genetic effects from diploid embryo nuclear genes, cytoplasmic genes and diploid maternal plant nuclear genes were all important for the performance of both nutrient quality traits at most developmental times/stages. Results from the conditional analysis further revealed that the activation of quantitative genes was gradually carried through the developmental process with maternal genes playing more active role at most developmental stages. Additive effects from embryo and maternal plant were found more important than the dominant effects at most developmental times/stages for both traits, and especially for protein content of rapeseed. Heritability analysis confirmed that the maternal heritability for protein contents were considerably stronger throughout developmental period except for the developmental time at 22 days, while for oil content the heritability components were dynamic and time dependent. The differences of genetic relationships from various genetic systems were found for oil and protein contents among the developmental times or between the two quality traits. © 2008 Springer Science+Business Media B.V.",
        "keywords": [
            "developmental genetics",
            "genetic correlations",
            "genetic variances and conditional genetic variances",
            "heritability",
            "oil content",
            "protein content",
            "rapeseed",
            "quantitative trait",
            "embryos",
            "quantitative traits",
            "genetic analysis",
            "genetic variance",
            "genetics",
            "relationships",
            "developmental stages",
            "diploidy",
            "genes"
        ],
        "authors": [
            {
                "name": "Murali Tottekkaad Variath",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yunxia Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Guolin Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Cuihua Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Euphytica",
        "year": 2009
    },
    "jShtGPWs": {
        "id": "jShtGPWs",
        "title": "Antioxidant and Anti-proliferative Activities of Flavonoids from Bidens pilosa L var radiata Sch Bip",
        "abstract": "Purpose:  To investigate the chemical composition of  Bidens pilosa  L. var.  radiata . Sch Bip. (BP), as well as its antioxidant and anti-proliferative activities.   Methods:  The whole herb of BP was extracted with 95 % ethanol, which was then partitioned sequentially with petroleum ether, ethyl acetate and n-butyl alcohol to obtain petroleum ether, ethyl acetate (EE-BP), n-BuOH and water fractions. EE-BP was further isolated and purified by repeated column chromatography. The obtained compounds were identified by comparing 1H and 13C nuclear magnetic resonance (NMR) spectra with published data for the compounds. Flavonoids were evaluated for 1,1-diphenyl-2-picrylhydrazy (DPPH) and 2, 2 -azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) free radical scavenging activity by colorimetric methods, while their anti-proliferative effect against human colon cancer RKO cells was determined by 3-(4,5) dimethylthiahiazo (-z-y1)-3,5-diphenytetrazoliumromide (MTT) method.   Results:  A total of 6 compounds were isolated from BP, including flavonoids or flavonoid glycosides, among which were isoquercitrin (1), vitexin (2), astragalin (3), 5,6,7,4u0027-tetramethoxylflavone (4), 5,3u0027,4u0027- trihydroxy-3,7-dimethoxylflavone (5) and quercetin (6). The results indicate that compound 6 was the most effective in both DPPH and ABTS free radical-scavenging assays, with half maximal inhibitory concentration (IC50) of 10.7 μmol/L and 17.5 μmol/L, respectively. Both compounds 4 and 5 exhibited significant growth inhibitory effect on RKO cells with IC50 of 39.08 μmol/L and 17.68 μmol/L, respectively (p u003c 0.01).   Conclusion:  BP contains a series of flavonoid compounds, possessing significant antioxidant activity and antiproliferative effect in RKO cells, thus suggesting that it is a potential health supplement and an easily available resource of natural antioxidants for use in colon cancer prevention.   Keywords:   Bidens pilosa , Flavonoid, Antioxidant, Anti-proliferation, Colon cancer",
        "keywords": "",
        "authors": [
            {
                "name": "Jun Yi",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Yan-Bin Wu",
                "org": ""
            },
            {
                "name": "Wei Peng",
                "org": ""
            }
        ],
        "venue": "Tropical Journal of Pharmaceutical Research",
        "year": 2016
    },
    "7kyfiRPK": {
        "id": "7kyfiRPK",
        "title": "Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-κB",
        "abstract": "High levels of interleukin-6 (IL-6) in the acute stage associated with lung lesions were found in SARS patients. To evaluate the mechanisms behind this event, we investigated the roles of SARS-CoV proteins in the regulation of IL-6. Results showed that the viral nucleocapsid (N) protein activated IL-6 expression in a concentration-dependent manner. Promoter analyses suggested that NF-kappaB binding element was required for IL-6 expression regulated by N protein. Further studies demonstrated that N protein bound directly to NF-kappaB element on the promoter. We also showed that N protein activated IL-6 expression through NF-kappaB by facilitating the translocation of NF-kappaB from cytosol to nucleus. Mutational analyses revealed that two regions of N protein were essential for its function in the activation of IL-6. These results provided new insights into understanding the mechanism involved in the function of SARS-CoV N protein and pathogenesis of the virus.",
        "keywords": [
            "Virus infection",
            "Gene regulation",
            "SARS-CoV",
            "IL-6",
            "Pathogenesis",
            "N protein",
            "NF-κB",
            "Inflammation"
        ],
        "authors": [
            {
                "name": "Xue Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, P.R. China"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, P.R. China"
            },
            {
                "name": "Di Wang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, P.R. China"
            },
            {
                "name": "Xin Yue",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, P.R. China"
            },
            {
                "name": "Degui Song",
                "org": "College of Biological Sciences, Guangxi Normal University, Guilin 541004, P.R. China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2007
    },
    "XZTHgDjC": {
        "id": "XZTHgDjC",
        "title": "Study on Conditions of Lipid Produced by Cunninghamella Echinulata in Unsterilized Solid State Fermentation",
        "abstract": "Using Cunninghamella echinulata B5 as an experimental object because of its high capability to produce lipid,after studying many factors that influenced B5′s unsterilized solid state fermentation and making analysis of kinetics curve of fermentation process,the optimum conditions for B5′s unsterilized solid state fermentation to produce lipid were: used 5g corn straw as basic solid culture medium,added 3.50g glucose and 0.15g ammonium nitrate,and then added 0.025g citric acid,0.02g zinc sulfate and 8mL water,inoculated with 10mL cultivated seed liquid.On the basis of these conditions,along with natural pH,25℃ and 8d′s fermentation,the percentage of lipid content could remain about 13% in dry substrate.",
        "keywords": [
            "conditions",
            "Cunninghamella echinulata",
            "unsterilized solid state fermentation",
            "lipid"
        ],
        "authors": [
            {
                "name": "GAO Shi",
                "org": "College of Life Sci.and Technology,Huazhong Univ.of Sci.and Technology,Wuhan ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Life Sci.and Technology,Huazhong Univ.of Sci.and Technology,Wuhan ,China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "College of Life Sci.and Technology,Huazhong Univ.of Sci.and Technology,Wuhan ,China"
            },
            {
                "name": "LIU Ping",
                "org": "College of Life Sci.and Technology,Huazhong Univ.of Sci.and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Hubei University of Technology",
        "year": 2009
    },
    "jtsHhyEe": {
        "id": "jtsHhyEe",
        "title": "The Potential Impact of Climate Change on the Suitable Climatic Distribution Region of Alpine Meadows in Qinghai-Tibet Plateau",
        "abstract": "It is crucial to understanding the effects of climate change on the distribution of terrestrial ecosystem for the environmental protection following climate change.The alpine meadow is an ecosystem type sensitive and vulnerable to climate change.To understand the impacts of climate change on the potential distribution of alpine meadows,the effects of climate change on the suitable climatic distribution region of alpine meadows in Qinghai-Tibet plateau were analyzed using Holdridge Life Zone System under climate change scenarios of A1,A2,B1 and B2.The results show that climate change in China would cause a decrease in the suitable climatic distribution region of alpine meadows under baseline climate scenario,an increase in the new suitable climatic distribution region of alpine meadows,while no change in total suitable climatic distribution region of alpine meadows.And climate change in China would also cause a decrease in the minimum,maximum,and median of suitable climatic distribution region of alpine meadows under baseline climate scenario,an increase in the minimum,maximum and median of new suitable climatic distribution region of alpine meadows,and no change in the minimum,maximum and median of total suitable climatic distribution region of alpine meadows.Additionally,following climate change,the south of suitable climatic distribution region of alpine meadows under baseline climate scenario would reduce,and new suitable climatic distribution region would expand mainly towards west and northwest of suitable climatic distribution region of alpine meadows under baseline climate scenario,and they were the highest in A1 scenario and the lowest in B1 scenario among climate change scenarios of A1,A2,B1 and B2 following climate change.Following climate change,the change of the suitable climatic distribution region under baseline climate scenario,new suitable climatic distribution region,and total suitable climatic distribution region of alpine meadows were all positively correlated with the changes in annual mean air temperature and precipitation in China,and the effects of increasing annual mean air temperature in China were higher than that of increasing annual precipitation.The results indicate that climate change in China would cause a decrease in the distribution region under baseline climate scenario and an increase in the expanding distribution region of alpine meadows,and the spatial distribution pattern would change greatly.",
        "keywords": [
            "alpine meadows",
            "climate change",
            "suitable climatic distribution region",
            "plateaux",
            "air temperature",
            "precipitation",
            "climatic change",
            "climate"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "LV Jia-jia",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Acta Agrestia Sinica",
        "year": 2009
    },
    "88YstNoq": {
        "id": "88YstNoq",
        "title": "Analysis of genetic effects for cooking quality traits of japonica rice across environments",
        "abstract": "The genetic effects of the cooking quality traits amylose content (AC) and gel consistency (GC) of japonica rice were analyzed by using a genetic model including genotype × environment (GE) interaction effects for quality traits of the endosperm in cereal crops. The results indicated that AC and GC of japonica rice were greatly controlled by the genetic main effects from endosperm, cytoplasm and maternal plant genes, but were also affected by GE interaction effects. The endosperm effects were most important among genetic main effects for the performance of AC and GC, while the cytoplasmic interaction effect or maternal interaction effects for AC or GC were more essential among GE interaction effects, respectively. Additive effects and cytoplasmic interaction effect were the main factors controlling the performance of AC, but GC was mainly affected by additive effects, additive interaction effects and cytoplasmic interaction effect. The endosperm general heritabilities were the largest ones among heritability components for AC and GC. A significant negative genotypic correlation was found between AC and GC. The genetic effects predicted for 13 parents showed that Liaojing 326 A and Hu 161 were the better parents for improving the rice cooking quality traits. © 2005 Elsevier Ireland Ltd. All rights reserved.",
        "keywords": [
            "cooking quality traits",
            "genetic correlations",
            "genetic main effects",
            "genotype x environment interaction effects",
            "heritabilities",
            "japonica rice",
            "genotype environment interaction",
            "genetics",
            "genetic correlation",
            "interaction effect"
        ],
        "authors": [
            {
                "name": "Jianrong Lin",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Mingguo Wu",
                "org": "China National Rice Research Institute(China National Rice Research Institute,China Natl. Rice Research Institute),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Plant Science",
        "year": 2005
    },
    "aeSaWbyw": {
        "id": "aeSaWbyw",
        "title": "Toward a Landscape Ecology of Cities: Beyond Buildings, Trees, and Urban Forests",
        "abstract": "Human population growth and urbanization are two dominant demographic trends in our time (Brown, 2001). World population has\n continued to grow exponentially for the past several decades, and reached 6.2 billion in 2002, with a current annual increase\n rate of almost 80 million (Earth Policy Institute, 2002). The proportion of the total world population that is urban was only\n a few percent in the 1800s, but it increased to 14% by 1900, rapidly jumped to about 30% in 1950 (Platt, 1994a; Wu and Overton,\n 2002), and is passing 50% now. Evidently, as the world’s human population has increased exponentially, so has the proportion\n of people living in cities (Fig. 2.1). It has been projected that 60% of the world’s population will reside in urban areas\n by 2025 (Platt, 1994a). In 1800, there was only one city, Beijing, in the entire world that had more than a million people;\n 326 such cities existed 200 years later (Brown, 2001). The urban population is growing three times faster than the rural population\n (Nilsson et al., 1999), and we are now witnessing a historically unprecedented and monumental, global-scale, rural-to-urban\n transition. To quote Lester Brown (2001), “For the first time, we will be an urban species!”\n \n At a more regional scale, urban people already account for more than two thirds of the European population today. In the United\n States, 74% of the population resided in urban areas in 1989, and this number will increase to more than 80% by 2025 (Pickett\n et al., 2001). The historical record so far has shown that both the number of mega-cities as well as the number of urban dwellers\n have increased much faster in developing countries than in developed countries. For example, nearly 40% of the population\n of the Asia-Pacific region is now urban, and the region contains 13 of the 25 largest cities of the world. It has been estimated\n that by 2015 about 903 million people in Asia will live in cities with a population of over one million people (cf. Wu and\n Overton, 2002). While the world’s urban population is projected to rise to 60% by 2025, nearly half of these people will reside\n in the Asia-Pacific region. Undoubtedly, urbanization will continue to have significant impact on the environment as well\n as on economic, social, and political processes at local, regional, and global scales.\n \n \n ",
        "keywords": [
            "urbanization",
            "landscape ecology",
            "community ecology",
            "urban development"
        ],
        "authors": [
            {
                "name": "j g wu",
                "org": "arizona state university"
            },
            {
                "name": "m m carreiro",
                "org": "arizona state university"
            },
            {
                "name": "y c song",
                "org": "arizona state university"
            }
        ],
        "venue": "",
        "year": 2008
    },
    "Wrv5OlIt": {
        "id": "Wrv5OlIt",
        "title": "Research on Candidates Selection Methods of Beam Search Algorithm",
        "abstract": "The hill-climbing search through hypothesis space is widespread used in many learning algorithms.It can’t grantee getting the globally optimal solution.In order to reduce the risk of converging to locally optimal hypotheses,beam search approach is explored.But in most of search algorithms,the k candidates with the most high performance measure value are selected.This paper presents some variations of beam search approaches.With these approaches,the k candidates could be selected in more reasonable way that can reduce the risk of converging to locally optimal solution in some extent.The experiments are done on the UCI repository of machine learning databases.",
        "keywords": [
            "Clustering",
            "Beam search",
            "Machine learning",
            "Inductive logic programming"
        ],
        "authors": [
            {
                "name": "XU Zhongwei",
                "org": "Ministry of Education’s Key Laboratory of Intelligence Computing and signal Processing,Anhui University,Hefei ;Dept.of Computer Science,Shandong University in Weihai,Weihai "
            },
            {
                "name": "LI Wei",
                "org": "Ministry of Education’s Key Laboratory of Intelligence Computing and signal Processing,Anhui University,Hefei "
            },
            {
                "name": "WU Jianguo",
                "org": "Ministry of Education’s Key Laboratory of Intelligence Computing and signal Processing,Anhui University,Hefei "
            }
        ],
        "venue": "Computer Engineering",
        "year": 2007
    },
    "HhZRdB6t": {
        "id": "HhZRdB6t",
        "title": "Osa-miR164a targets OsNAC60 and negatively regulates rice immunity against the blast fungus Magnaporthe oryzae.",
        "abstract": "Exploring the regulatory mechanism played by endogenous rice miRNAs in defense responses against the blast disease is of great significance in both resistant variety breeding and disease control management. We identified rice defense-related miRNAs by comparing rice miRNA expression patterns before and after Magnaporthe oryzae strain Guy11 infection. We discovered that osa-miR164a expression reduced upon Guy11 infection at both early and late stages, which was perfectly associated with the induced expression of its target gene, OsNAC60. OsNAC60 encodes a transcription factor, over-expression of which enhanced defense responses, such as increased programmed cell death, greater ion leakage, more ROS accumulation and callose deposition, and up-regulation of defense-related genes. By using transgenic rice over-expressing osa-miR164a, and a transposon insertion mutant of OsNAC60, we showed that when the miR164a/OsNAC60 regulatory module was dysfunctional, rice developed significant susceptibility to Guy11 infection. The co-expression of OsNAC60 and osa-miR164a abolished the OsNAC60 activity, but not its synonymous mutant. We further validated that this regulatory module is conserved in plant resistance to multiple plant diseases such as the rice sheath blight, tomato late blight, and soybean root and stem rot diseases. Our results demonstrate that the miR164a/OsNAC60 regulatory module manipulates rice defense responses to M. oryzae infection. This discovery is of great potential for resistant variety breeding and disease control to a broad spectrum of pathogens in the future. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "NAC transcription factor",
            "defense",
            "microRNA",
            "rice blast",
            "silencing"
        ],
        "authors": [
            {
                "name": "Zhaoyun Wang",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Yeqiang Xia",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Siyuan Lin",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Yanru Wang",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Baohuan Guo",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Xiaoning Song",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Shaochen Ding",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Liyu Zheng",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Ruiying Feng",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Shulin Chen",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Yalin Bao",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Cong Sheng",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Xin Zhang",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Dongdong Niu",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            },
            {
                "name": "Hailing Jin",
                "org": "Department of Plant Pathology and Microbiology, University of California, Riverside, CA, 92521, USA."
            },
            {
                "name": "Hongwei Zhao",
                "org": "The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, Jiangsu, 210095, China."
            }
        ],
        "venue": "The Plant journal : for cell and molecular biology",
        "year": 2018
    },
    "yh7JJKUU": {
        "id": "yh7JJKUU",
        "title": "Nonlinear Analysis of Air-bag for Ship Launching",
        "abstract": "The nonlinearity of the material,geometry and contact condition of air-bag used for ship launching was analyzed.Numerical simulation was carried out to analyze the relationship between inner and outer stress of the air-bag and compressive displacement by using the commercial nonlinear finite element analysis software MSC.Marc.The comparison between simulation and experiment results indicated that the method had high precision.The stress distribution of cord and rubber was also analyzed,which provided the basis for air-bag design.",
        "keywords": [
            "finite element analysis",
            "nonlinearity",
            "ship launching",
            "air-bag"
        ],
        "authors": [
            {
                "name": "LIU Zhi-yi",
                "org": "Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "SUN Ju-xiang",
                "org": "The Factory of Changlin Air-bag Container,Jinan ,China"
            }
        ],
        "venue": "China Rubber Industry",
        "year": 2012
    },
    "rqWaSEZ9": {
        "id": "rqWaSEZ9",
        "title": "Preparation and Application of Antibody for Unknown Protein Interacting with HBx Protein",
        "abstract": "The DNA fragment including 3′-terminate of UK gene was amplified from plasmid pOT-UK by PCR and cloned into plasmid pET28;the new plasmid was named pET28-UK.The plasmid pET28-UK was transformed into E coli.BL21.Protein UK was expressed by inducing transformed BL21 with IPTG and purified by ringing using PBS.The protein UK mixed with completed Ford's adjuvant was first injected rabbits,and then injected with UK protein with uncompleted Ford's adjuvant.10 days later after last immunity with UK protein,the serum of rabbits was extracted from heart.The antibody can identify the protein UK in the cells by immunofluorescence.",
        "keywords": [
            "application",
            "antibody",
            "HBx protein",
            "UK protein"
        ],
        "authors": [
            {
                "name": "ZHANG Jian-lin",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "SI Wei",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "ZHAO Wei-guang",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "HUANG Jing",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "ZHU Ying",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "LI Yan",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "ZHANG Xiao-lian",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            }
        ],
        "venue": "Wuhan University Journal(Natural Science Edition)",
        "year": 2005
    },
    "K3rDFkCv": {
        "id": "K3rDFkCv",
        "title": "Thirty years of <Emphasis Type=\"Italic\">Landscape Ecology</Emphasis> (1987–2017): retrospects and prospects",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, School of Sustainability, and Julie A. Wrigley Global Institute of Sustainability,Arizona State University,Tempe,USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2017
    },
    "fxImhuZi": {
        "id": "fxImhuZi",
        "title": "The screening of mutants induced by physical and chemical factors and construction of mutant population for Brassica napus L]",
        "abstract": "The mature seeds of rapeseed (Brassica napus L.) from variety Gaoyou 605 were treated with g-rays and Ethyl Methan Sulfonate (EMS). 152 mutants (12.67% of M2 population) with mutative traits, including the mutation of leaf color, leaf shape, plant height, number and angle of branches, diameter of main stalk, color of stalk and flower, number and size of petals, pistil shape, male sterility, bud death and date of bloom were found in screened M2 progenies, which have been identified in M3. The mutants of cotyledon and root traits were also screened by hydroponics culture and their total mutant frequency were estimated at 12.78% and 7.07% in M3, respectively. Identification of M4 showed that these mutations could be inherited stably. The mutant library including the mutants of leaf, plant-type, flower, cotyledon, root and physiological traits had been built in present experiment. These mutants might be used as important germplasm for rapeseed breeding and functional genomics study.",
        "keywords": [
            "ethyl methan sulfonate (ems)",
            "γ-rays",
            "rapeseed (brassica napus l.)",
            "mutagenesis"
        ],
        "authors": [
            {
                "name": "Jia-Yan Sun",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China. jysunphd@zj.com"
            },
            {
                "name": "Jin-Dong Tu",
                "org": ""
            },
            {
                "name": "Shu-Wei Fan",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2007
    },
    "HVuwVyax": {
        "id": "HVuwVyax",
        "title": "Plant regeneration from hypocotyl protoplasts of red cabbage (Brassica oleracea) by using nurse cultures",
        "abstract": "A protocol for rapid and efficient plant regeneration from protoplasts of red cabbage was developed by a novel nurse culture method. When the protoplasts of red cabbage were cultured in modified MS medium containing various combinations of BA, NAA and 2,4-D, they did not continue dividing due to browning. However, they successfully divided and formed micro-calli at a high efficiency when they were mixed and co-cultured with those of tuber mustard at a 1:1 ratio. The presence of tuber mustard protoplasts used as nurse cells was essential for sustainable divisions and colony formation of red cabbage protoplasts. Red cabbage-like plantlets were regenerated from these protoplast-derived calli at a frequency ranging from 33 to 56% in all the experiments where three cultivars of red cabbage were tested. Over 120 protoplast-derived cabbage plants were transferred to the greenhouse, and they showed no noticeable abnormalities in morphological features. Chromosome observation revealed that all of the plants examined had the normal chromosome number of cabbage (2n = 18), suggesting that no spontaneous fusion between the two species had occurred during protoplast culture.",
        "keywords": [
            "chromosome observation",
            " efficient plant regeneration",
            " tuber mustard"
        ],
        "authors": [
            {
                "name": "Li-Ping Chen",
                "org": "Department of Horticulture, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,P.R. China"
            },
            {
                "name": "Ming-Fang Zhang",
                "org": "Department of Horticulture, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,P.R. China"
            },
            {
                "name": "Qiu Bing Xiao",
                "org": "Graduate School of Agriculture,Tokyo University of Agriculture and Technology,Fuchu, Tokyo,Japan"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,P.R. China"
            },
            {
                "name": "Yutaka Hirata",
                "org": "Graduate School of Agriculture,Tokyo University of Agriculture and Technology,Fuchu, Tokyo,Japan"
            }
        ],
        "venue": "Plant Cell, Tissue and Organ Culture",
        "year": 2004
    },
    "ugnytdj4": {
        "id": "ugnytdj4",
        "title": "Double-level osteotomy and one-stage reconstruction with long intramedullary femoral nail to correct a severe proximal and diaphyseal femur deformity in a patient with polyostotic fibrous dysplasia: case report and literatures review.",
        "abstract": "Proximal femur is often involved with varus and retroversion deformity in polyostotic fibrous dysplasia (PFD). Multiple corrective osteotomies with intramedullary nails in two stages is recommended procedure as some authors described. We report a case using double-level osteotomy and one-stage reconstruction with intramedullary nail in a patient with painful proximal femur and diaphysis varus deformity, the neck-shaft angle was corrected from 95° pre-operatively to 125° post-operatively, the patient was free of pain and no evidence of recurrence at the 24-month follow up. The operative design and method were described, and a review of related literatures about the treatment alteration for PFD and relevant operative selection were also performed.",
        "keywords": [
            "Polyostotic fibrous dysplasia",
            "Shepherd’s deformity",
            "internal-fixation",
            "osteotomy"
        ],
        "authors": [
            {
                "name": "Feiyan Chen",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Yibing Wei",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Jun Xia",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Siqun Wang",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Gangyong Huang",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Jie Chen",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            },
            {
                "name": "Jingsheng Shi",
                "org": "The Department of Orthopedics, Huashan Hospital, Fudan University Shanghai, China."
            }
        ],
        "venue": "International journal of clinical and experimental medicine",
        "year": 2015
    },
    "V9V9nIFa": {
        "id": "V9V9nIFa",
        "title": "Verification of Controller Synthesis Based on Completely Specified Finite State Machine",
        "abstract": "Controller synthesis uses hardware description language and synthesis optimization tools from a higher abstract level. State transition graph of completely specified finite state machine is adopted to describe the behavior of controller. State transition graph STG_org was generated before synthesized and state transition graph STG_ext was reversely extracted from structure realization of controller synthesis. If STG_org and STG_ext were equivalent then corresponding process of controller synthesis was correct. The paper gives a formal verification algorithm of controller synthesis with time complexity O(B2/Aldrt1(n)+Aldrt2(m,n)) .In order to further improve time complexity of algorithm, a verifying algorithm with synthetic information guidance was proposed. The algorithm is proved efficient in theory for its time complexity is decreased to O(Bldrt1(n) + Aldrt2(m,n)).",
        "keywords": [
            "sequential circuits",
            "finite state machines",
            "state transition graph",
            "special image",
            "finite state machine",
            "equivalence",
            "logic cad",
            "time complexity",
            "formal verification algorithm",
            "hardware description languages",
            "controller synthesis verification",
            "completely specified finite state",
            "computational complexity",
            "sufficient information",
            "graph theory",
            "camera result",
            "controller synthesis",
            "camera calibration",
            "hardware description language",
            "formal verification",
            "completely specified finite state machine",
            "process control",
            "automata",
            "combinational circuits"
        ],
        "authors": [
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Yichao Zhang",
                "org": ""
            },
            {
                "name": "Zhengyi Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Information Science and Engineering, 2008. ISISE '08. International Symposium",
        "year": 2008
    },
    "hGXjMsdG": {
        "id": "hGXjMsdG",
        "title": "A hierarchical patch mosaic ecosystem model for urban landscapes: Model development and evaluation",
        "abstract": "Urbanization effects on ecosystem functions are both important and complex, characterized by scale multiplicity, spatial heterogeneity, and intensive human disturbances. Integrating the hierarchical structure of urban landscape pattern with ecosystem processes through simulation modeling can facilitate our understanding of human-environment interactions in urban environment. Current ecosystem models often focus on plant physiological and biogeochemical processes in homogeneous land covers, incapable of addressing the structural complexity in urban landscapes with multiple anthropogenic drivers across a range of spatial scales. Here we present the Hierarchical Patch Mosaic-Urban Ecosystem Model (HPM-UEM), a multi-scaled model that explicitly treats spatial pattern and hierarchical structure of urban landscape by incorporating both top-down controls and bottom-up mechanisms in urban environment. By addressing six hierarchical levels from individual plant to the urbanized region, HPM-UEM provides a \" hierarchical ladder\" to scale up local ecosystem functions across the nested urban land hierarchies (i.e., land cover, land use, landscape, and the urbanized region), and facilitate linking ecosystem processes and socioeconomic drivers. By organizing human influences in a spatially nested hierarchical patch mosaic structure, HPM-UEM models the complex spatiotemporal pattern of multiple environmental constraints on urban ecosystem functions. The model was evaluated based on extensive datasets developed by the Long-Term Ecological Research (LTER) network, especially the Central Arizona-Phoenix (CAP) LTER. Model testing results showed that HPM-UEM predicted both C fluxes and spatial pattern of C stocks with reasonable accuracy. HPM-UEM enabled us to assess spatial patterns and multiple-scaled dynamics of C cycle of the urban landscape, revealing the distinct productivities and C densities of different urban land types across different spatial scales. Sensitivity analyses indicated that future environmental changes and landscape modifications could have strong and complex effects on urban ecosystem functions. By matching ecological processes, anthropogenic environmental controls, and land and socioeconomic dynamics based on hierarchical levels, HPM-UEM could be coupled to multiple-scaled urban land-use models, climate models, and socioeconomic models to gain a comprehensive understanding of urban biogeochemical cycles. © 2012 Elsevier B.V.",
        "keywords": [
            "carbon cycle",
            "hierarchical patch dynamics paradigm",
            "lter",
            "phoenix metropolitan area",
            "process-based model",
            "urban ecosystem"
        ],
        "authors": [
            {
                "name": "Chi Zhang",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Nancy B. Grimm",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Melissa R. McHale",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Alexander Buyantuyev",
                "org": "Inner Mongolia University China(Inner Mongolia University,Inner Mongolia University of Technology),Huhhot,China"
            }
        ],
        "venue": "Ecological Modelling",
        "year": 2013
    },
    "sPyk0kO2": {
        "id": "sPyk0kO2",
        "title": "Research on Syllable Segmentation Method",
        "abstract": "Syllable segmentation lays the foundation for sentence pinyin conversion.As a result of the particularity of pinyin syllable segmentation has different ways.One partition result can be got by least participle algorithm so that correctness of sentence pinyin conversion can not be guaranteed.Presents a syllable segmentation algorithm which is composed of two kinds of nodes. One is phoneme node,the other is syllable node.Phoneme nodes are integrated into syllable node.They link with chain to form state space.Can get all the possible partition results by traversal algorithm.When encountering user's deletion operation it only need to delete some nodes related.State space is adjusted locally and equably along with user's operation.This algorithm is in favor of sentence conversion with different partition ways.It can get an optimal answer from all the possible partition.",
        "keywords": [
            "various segmentation",
            "state space",
            "syllable segmentation",
            "sentence input method",
            "partition algorithm"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "LIU Hui-ting",
                "org": ""
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2008
    },
    "3p2qFZDq": {
        "id": "3p2qFZDq",
        "title": "The touch technology research based on binocular vision",
        "abstract": "This article has designed an implementation method of touch screen based on binocular vision technology.It mainly adopts two ordinary cameras as sensors to capture the existence of the touch material objects and actions in real-time.And using computer vision techniques to achieve virtual touch functionality on the normal display screen to make it to click,double-click,drag and multi-touch capabilities.",
        "keywords": [
            "touch screen",
            "computer vision",
            "image processing",
            "image sequences",
            "human-computer interaction"
        ],
        "authors": [
            {
                "name": "Zhu Lijin",
                "org": "Key Laboratory of Computing & Signal Processing,Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "Key Laboratory of Computing & Signal Processing,Ministry of Education,Anhui University,Hefei ,China;Computer Science and Technical Institute,Anhui University,Hefei ,China"
            },
            {
                "name": "Guo Xing",
                "org": "Key Laboratory of Computing & Signal Processing,Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "Li Wei",
                "org": "Key Laboratory of Computing & Signal Processing,Ministry of Education,Anhui University,Hefei ,China;Computer Science and Technical Institute,Anhui University,Hefei ,China"
            },
            {
                "name": "Liu Jun",
                "org": "Key Laboratory of Computing & Signal Processing,Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Microcomputer & Its Applications",
        "year": 2011
    },
    "mjXLzRZJ": {
        "id": "mjXLzRZJ",
        "title": "Origin of highly pathogenic H5N1 avian influenza virus in China and genetic characterization of donor and recipient viruses.",
        "abstract": "Genetic analysis of all eight genes of two Nanchang avian influenza viruses, A/Duck/Nanchang/1681/92 (H3N8-1681) and A/Duck/Nanchang/1904/92 (H7N1-1904), isolated from Jiangxi province, China, in 1992, showed that six internal genes of H3N8-1681 virus and five internal (except NS gene) genes of H7N1-1904 virus were closely similar to A/Goose/Guangdong/1/96 (H5N1) virus, the first highly pathogenic avian influenza (HPAI) virus of subtype H5N1 isolated in Asia. The neuraminidase (NA) gene of Gs/Gd/1/96 had the highest genetic similarity with A/Duck/Hokkaido/55/96 (H1N1-55) virus. The haemagglutinin (HA) gene of Gs/Gd/1/96 virus might have originated as a result of mutation of H5 HA gene from A/Swan/Hokkaido/51/96 (H5N3-51)-like viruses. The PA gene of H5N3-51 virus had the highest similarity with Gs/Gd/1/96. This study explains the origin of first Asian HPAI H5N1 virus in Guangdong by the reassortment of Nanchang (close to Guangdong) and Hokkaido (Japan) (H1N1-55 and H5N3-51) viruses. Genetic characteristics of donor and recipient viruses were also studied.",
        "keywords": [],
        "authors": [
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": "Correspondence"
            },
            {
                "name": "Sahibzada T Rasool",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072"
            },
            {
                "name": "Degui Song",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072"
            },
            {
                "name": "Chengliang Zhu",
                "org": "Correspondence"
            },
            {
                "name": "Qian Hao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072"
            },
            {
                "name": "Ying Zhu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072"
            }
        ],
        "venue": "The Journal of general virology",
        "year": 2007
    },
    "DZwIVgcw": {
        "id": "DZwIVgcw",
        "title": "Effects of plastic film mulching cultivation under non-flooded condition on rice quality",
        "abstract": "",
        "keywords": [
            "appearance quality",
            "cooking and eating quality",
            "milling quality",
            "nutritional quality",
            "plastic film mulching cultivation",
            "rice (oryza stativa l.)"
        ],
        "authors": [
            {
                "name": "Xinghua Lu",
                "org": ""
            },
            {
                "name": "Lianghuan Wu",
                "org": ""
            },
            {
                "name": "Linjiang Pang",
                "org": ""
            },
            {
                "name": "Yongshan Li",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Chunhai Shi",
                "org": ""
            },
            {
                "name": "Fusuo Zhang",
                "org": ""
            }
        ],
        "venue": "Journal of The Science of Food and Agriculture",
        "year": 2007
    },
    "BmDFw5IK": {
        "id": "BmDFw5IK",
        "title": "The Discussion of Overtreatment on Clinical Traumatic Optic Neuropathy",
        "abstract": "Traumatic optic neuropathy (TON) is an important cause of severe visual loss following head or face trauma. In the course of TON treatment, overtreatment is common. There is not accepted treatment criterion anciently which is the mostly one in various reasons, this paper analyzes and discusses the current overtreatment in TON according to an up-to -date production or evidence based medicine (EBM). Furthermore, it provides the strategy that the doctor should be adapted on overtreatment in TON to achieve the optimization medical care.",
        "keywords": [
            "traumatic optic neuropathy",
            "evidence based medicine",
            "optimization medical care",
            "overtreatment"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": ".Wuhan general Hospital of Guangzhou Military command, Wuhan ,China"
            },
            {
                "name": "ZHOU He-zheng",
                "org": ".Wuhan general Hospital of Guangzhou Military command, Wuhan ,China"
            }
        ],
        "venue": "Medicine & Philosophy(Clinical Decision Making Forum Edition)",
        "year": 2006
    },
    "lrxA4HuJ": {
        "id": "lrxA4HuJ",
        "title": "Analysis of genetic effects and heritabilities for linoleic and α-linolenic acid content of Brassica napus L. across Chinese environments",
        "abstract": "A genetic model for quantitative traits of seed in diploid plant was applied to analyze the main genetic effects and genotype x environment (GE) interaction effects for linoleic and α-linolenic acid content of rapeseed (Brassica napus L.) by using two year experimental data with 8 parents and their F1 and F2. Results indicated that the performance of linoleic (C18:2) and α-linolenic acid content (C18:3) of rapeseed were simultaneously controlled by diploid embryo nuclear genes, cytoplasmic genes and diploid maternal plant nuclear genes, and the GE interaction effects for these two seed quality traits were more important than the genetic main effects. The total narrow-sense heritability was 69.5% and 41.8% for C18:2 and C18:3, respectively, and the GE interaction heritabilities were found to be larger than the general heritabilities for both quality traits. It was suggested by the predicted genetic effects that Huashuang 3 was better than other parents for improving offspring of C18:2 and Youcai 601, Zhongyou 821, Eyouchangjia and Zhong R-888 for decreasing C18:3.",
        "keywords": [
            "fatty acid",
            "genetic effect",
            "heritability",
            "quality",
            "rapeseed (brassica napus l.)"
        ],
        "authors": [
            {
                "name": "HaiZhen Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yuling Ren",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Changtao Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Dongqing Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "YaoFeng Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "European Journal of Lipid Science and Technology",
        "year": 2004
    },
    "QOXb6XXt": {
        "id": "QOXb6XXt",
        "title": "Regulation of the Caulobacter flagellar gene hierarchy; not just for motility.",
        "abstract": "The Caulobacter crescentus flagellum serves not only as a motility apparatus, but also as a key landmark in the differentiation of this asymmetrically dividing bacterium. A distinctive aspect of flagellum biosynthesis is the periodic expression of the flagellar genes during the cell cycle in a sequence corresponding to the order of gene product assembly into the growing flagellum. This program of gene expression is achieved in part by the organization of flagellar genes into a four-tiered regulatory hierarchy that controls their expression at both the transcriptional and post-transcriptional levels. Because of the close interconnection of the developmental program to the asymmetric cell-division cycle in C. crescentus, studies of flagellar gene regulation and motility have also begun to reveal basic mechanisms responsible for control of the cell cycle itself. Here, we review recent work on regulation of the flagellar gene hierarchy in C. crescentus and consider regulatory mechanisms that are distinct from those described in Escherichia coli and Salmonella typhimurium.",
        "keywords": [],
        "authors": [
            {
                "name": "J Wu",
                "org": ""
            },
            {
                "name": "A Newton",
                "org": ""
            }
        ],
        "venue": "Molecular microbiology",
        "year": 1997
    },
    "vozBN0Ql": {
        "id": "vozBN0Ql",
        "title": "From the Angle of Defining the Roles as in Drama to See the Dramatic Thought of LiYu's Short Stories",
        "abstract": "If making an analysis of Invaluable Jewel and Twelve Towers carefully from the angle of defining the characters,we may discover intuitively that the chuanqi's theatrical ostentation had been used in these two collections of short story consciously and they appeared on the basic situation of being reborn audaciously.They are Li Weng's basic narrative strategies for making people feel refreshing: On one hand,he had choiced the regular \"sheng-dan\" form in chuanqi skillfully to tell the love entanglements about the talented men and beautiful women like enemies and like lovers in the specific hypothesized space;On the other hand,Li Yu had described exceedingly strang human comedy by setting up an alternative relationship-\"chou(jing)—dan(sheng)\" or \"jing—chou\" form on purpose in order to achieve the target of comedy narration.",
        "keywords": [
            "LiYu's short stories",
            "Defining the roles as in drama",
            "Dramatic thought",
            "Chuanqi's ostentation"
        ],
        "authors": [
            {
                "name": "FAN Yan-ping",
                "org": "Department of Chinese,Hunan Normal University,Changsha "
            },
            {
                "name": "WU Jian-guo",
                "org": "Department of Chinese,Hunan Normal University,Changsha "
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2006
    },
    "PQPvD68Y": {
        "id": "PQPvD68Y",
        "title": "Angiography reveals early hiding iris neovascularization after ischemic CRVO.",
        "abstract": "",
        "keywords": [
            "biomedical research",
            "bioinformatics"
        ],
        "authors": [
            {
                "name": "Zhi-Qing Li",
                "org": "Tianjin Medical University Eye Hospital, Tianjin 300384, China."
            },
            {
                "name": "Xiao-Xu Zhou",
                "org": ""
            },
            {
                "name": "Song Lin",
                "org": ""
            },
            {
                "name": "Jun-Ling Li",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            }
        ],
        "venue": "International journal of ophthalmology",
        "year": 2013
    },
    "AM6BcgSL": {
        "id": "AM6BcgSL",
        "title": "Blowing litter across a landscape: effects on ecosystem nutrient flux and implications for landscape management",
        "abstract": "Lateral flows in landscape mosaics represent a fundamentally important process in landscape ecology, but are still poorly\n understood in general. For example, windblown litter nutrient transfer across a landscape has rarely been studied from an\n ecosystem perspective. In this study we measured the litter nutrient transfer from an Acacia mangium plantation to a Dimocarpus longan orchard in an agroforestry landscape for 3 years from January 2002 to December 2004. About 11% of the total litterfall of\n the acacia plantation were transported to the longan orchard annually, accounting for ca. 9–59% of the total litter nutrient\n input of the longan orchard. The windblown litter transfer showed high spatial variation mainly caused by wind speed and directions.\n Slope positions 5 m away from the source acacia plantation received significantly greater amount of allochthonous acacia litter\n than those 10 m away, and the northwest-facing slope of the longan orchard received 2 to 3-fold more litter than the southeast-\n and south-facing slopes because of the prevailing southeasterly wind in the region. To explore how different management practices\n may influence the litterfall, leaf production, and soil nutrient status of the two ecosystems, we developed a Meta-Ecosystem\n Litter Transfer (MELT) model to simulate the processes of litter-related transformation (production, deposition, and decomposition)\n and transfer (wind- and management-driven movement). Our simulation results suggest that less than 30% of acacia litter should\n be transferred to the longan orchard in order for the acacia plantation to sustain itself and maximize production of the longan.\n Connectivity of nutrient flow between adjacent ecosystems as shown here leads to a functional meta-ecosystem with higher landscape-scale\n production of ecosystem services. That is, managing this connectivity through landscape design or active litter transfers\n can lead to large changes in overall landscape functioning and service production.",
        "keywords": [
            "agroforestry landscapelitter transfer � nutrient flowlandscape management",
            "spatial variation",
            "wind speed",
            "ecosystem service",
            "landscape ecology"
        ],
        "authors": [
            {
                "name": "Weijun Shen",
                "org": "Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, 723 Xinke Rd. Tianhe District, Guangzhou, 510650 China"
            },
            {
                "name": "Yongbiao Lin",
                "org": "Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, 723 Xinke Rd. Tianhe District, Guangzhou, 510650 China"
            },
            {
                "name": "G. Darrel Jenerette",
                "org": "Department of Botany and Plant Sciences, Center for Conservation Biology, University of California Riverside, Riverside, CA 92521, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2011
    },
    "V1ZA7ZS5": {
        "id": "V1ZA7ZS5",
        "title": "Lipid-soluble vitamin content and antioxidant activity of Ganoderma lucidum spores oil",
        "abstract": "Ganoderma lucidum spores oil was collected from the separator(at 8 MPa,45 ℃) by supercritical CO2 fluid extraction at 30 MPa and 40 ℃,with 25 L/h of CO2 flux for 2.0 h,and the averaged yield was 24.35% while the extract rate reached to 95.08%.High performance liquid chromatography analysis showed that the content of vitamin D2,D3 and E in the spores oil were 15.13,14.68 μg/g and 7.15 μg/g.The spores oil had positive antioxidant activity in vitro,which were mostly related to the tested samples concentrations.When the concentration of spores oil was 800 μg/mL,its scavenging ability on DPPH radical and superoxide radical were 89.1% and 41.3%,which were near to the degree of BHT and rutin,respectively;its scavenging effect on ABTS free radical was not obvious.",
        "keywords": [
            "antioxidant activity",
            "Ganoderma lucidum spores oil",
            "lipid-soluble vitamins"
        ],
        "authors": [
            {
                "name": "CHEN Tiqiang",
                "org": "Institute of Edible Fungi,Fujian Academy of Agricultural Sciences,Fuzhou ,China"
            },
            {
                "name": "WU Yanbin",
                "org": "Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine, Fuzhou ,China"
            },
            {
                "name": "MAO Fanghua",
                "org": "Institute of Edible Fungi,Fujian Academy of Agricultural Sciences,Fuzhou ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine, Fuzhou ,China"
            },
            {
                "name": "WANG Hongyu",
                "org": "Institute of Edible Fungi,Fujian Academy of Agricultural Sciences,Fuzhou ,China"
            }
        ],
        "venue": "China Oils and Fats",
        "year": 2012
    },
    "Q608NOjq": {
        "id": "Q608NOjq",
        "title": "The Value Orientation and Narration Mode of \"Xin Shi Yan\"",
        "abstract": "\"Xin Shi Yan\",a \"NiHuaBen\" novel of late Ming Dynasty,with a compiling purpose of \"Setting Models on Later Generation\",possesses an obvious value orientation of regenerating traditional culture through preserving strictly conflict ethical code as well as discarding sophisticate human craving,compared with other NiHuaBen novels in the corresponding period in subject choices,situation conflicts and characterization.The author combined narration with argument together and narrated the plots straightforwardly.Although simple,the plots suffer from lack of artistic feature.The author laid too much emphasis on the novel's enlightening instead of entertaining function,causing a wide gap in artistic value between \"Xin Shi Yan\" and other NiHuaBen novels in the corresponding period.",
        "keywords": [
            "narration mode",
            "value orientation",
            "scholars of the late Ming Dynasty",
            "enlightening first"
        ],
        "authors": [
            {
                "name": "LI Yi",
                "org": "College of Literature,Hunan University,Changsha ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Literature,Hunan Normal University,Changsha ,China"
            }
        ],
        "venue": "Journal of Hunan University(Social Sciences)",
        "year": 2007
    },
    "9C3GzOy3": {
        "id": "9C3GzOy3",
        "title": "Effects of plant functional group loss on soil biota and net ecosystem exchange: a plant removal experiment in the Mongolian grassland",
        "abstract": "SummaryThe rapid loss of global biodiversity can greatly affect the functioning of above-ground components of ecosystems. However, how such biodiversity losses affect below-ground communities and linkages to soil carbon (C) sequestration is unclear. Here, we describe how losses in plant functional groups (PFGs) affect soil microbial and nematode communities and net ecosystem exchange (NEE) in a 4-year removal experiment conducted on the Mongolian plateau, the worldu0027s largest remaining natural grassland.Our results demonstrated that the biomasses or abundances of most components of the two below-ground communities (microbes and nematodes) were negatively affected by PFG loss and were positively related to above-ground plant biomass. The removal of dominant PFGs (perennial bunchgrasses and perennial rhizomatous grasses) reduced the biomass or abundance of below-ground community components while removal of less dominant PFGs (perennial forbs and annuals/biennials) did not change or increased the biomass or abundance of below-ground community components.The biomass-based ratio of fungal to bacterial microbes and the number-based ratio of fungal-feeding to bacterial-feeding nematodes decreased with increasing PFG losses. Variation partitioning analyses showed that the identity of PFGs together with above-ground plant biomass explained most of the total variation in soil microbes and that the identity of PFGs and above-ground plant biomass together with nematode food resources explained most of the total variation in soil nematodes. The increase in NEE with PFG loss was mainly explained by decreases in above-ground plant biomass and the ratio of fungi to bacteria.Synthesis. The shift of below-ground communities from a fungal-based to a bacterial-based energy channel as PFG richness decreases indicates that less diverse grassland ecosystems will have lower nutrient retention and hence be more sensitive to land-use or climate change. The dominant effects of above-ground plant biomass and below-ground communities on NEE indicate that PFG loss resulting from land-use or climate change has the potential to reduce C sequestration in semi-arid grassland soils. These findings suggest that predictive models may need to consider the composition of above-ground and below-ground communities in order to accurately simulate the dynamics of CO2 fluxes in terrestrial ecosystems.",
        "keywords": "",
        "authors": [
            {
                "name": "Dima Chen",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            },
            {
                "name": "Qingmin Pan",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            },
            {
                "name": "Yongfei Bai",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            },
            {
                "name": "Shuijin Hu",
                "org": "Department of Plant Pathology North Carolina State University Raleigh NC 27695‐7616 USA"
            },
            {
                "name": "Jianhui Huang",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            },
            {
                "name": "Qibing Wang",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            },
            {
                "name": "Shahid Naeem",
                "org": "Department of Ecology, Evolution, and Environmental Biology Columbia University 1200 Amsterdam Avenue Schermerhorn Extension New York NY 10027 USA"
            },
            {
                "name": "James J. Elser",
                "org": "School of Life Sciences Arizona State University Tempe AZ 85287 USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences Arizona State University Tempe AZ 85287 USA"
            },
            {
                "name": "Xingguo Han",
                "org": "State Key Laboratory of Vegetation and Environmental Change Institute of Botany Chinese Academy of Sciences Beijing 100093 China"
            }
        ],
        "venue": "Journal of Ecology",
        "year": 2016
    },
    "zEEUrkCm": {
        "id": "zEEUrkCm",
        "title": "Social-ecological transformations of Inner Mongolia: a sustainability perspective",
        "abstract": "Sustainability requires the reconciling of human needs with the healthy natural ecosystem, which should be achieved within the grand course of industrialization and modernization. Systematic transitions on demography, economy, technology, and institutions are required, while different civilizations may take their respective paths. In this study, we analyze the social-ecological transitions of Inner Mongolia Autonomous Region of China during the past century, focusing on major changes in its environmental, demographic, and socioeconomic conditions.",
        "keywords": [
            "Sustainability transition",
            " Inner Mongolia",
            " Social-ecological system",
            " Demographic transition",
            " Modernization",
            " Ecological trap"
        ],
        "authors": [
            {
                "name": "Guang Hua Xu",
                "org": "School of Forestry and Bio-technology, Zhejiang A&F University, Lin’an, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, China"
            }
        ],
        "venue": "Ecological processes",
        "year": 2016
    },
    "e8tYpql9": {
        "id": "e8tYpql9",
        "title": "Implementation of Voting System for Image Processing Based on Mechatronics",
        "abstract": "By the analysis of voting system structure and the specific voting process,using the technology of image process and symbol recognition,a voting system is implemented based on mechatronics.The system is based on the OCR,adopts the unique overall box design,optimizes the image processing algorithm,through the positioning and segmentation extracts symbol,and finally identifies some handwritten symbols such as √、○、×、╲、-、╱,and carry out transmission,storage and statistics,realize fully automated processing for election.The election system fully implements the function of the automatic entry and automatic identification of votes,which enables the votes layout can be more complicated with a lot of information,make votes producing,saving,scribbling more convenient,is relatively advanced OCR network voting system.",
        "keywords": [
            "voting system",
            "image processing",
            "mechatronics",
            "symbol recognition"
        ],
        "authors": [
            {
                "name": "WANG Lei",
                "org": "College of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "HU Li-rui",
                "org": "College of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "YANG Jing",
                "org": "Hefei Artillery College,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2013
    },
    "r09NWatC": {
        "id": "r09NWatC",
        "title": "Creating a software package and improving the multimedia teaching of genetics course]",
        "abstract": "Multimedia as a pedagogical tool has been widely adopted for improving the quality of teaching. This paper describes the construction of a teaching software package based on the characteristics of the \"Genetics\" course. It also discusses some particulars of multimedia teaching, the collection of teaching materials, the improvement of teaching effects, and the compilation of a multimedia textbook. How to enhance the quality of the teachers as well as the motivation of the students are also discussed.",
        "keywords": [
            "genetics",
            "software",
            "course construction",
            "multimedia teaching"
        ],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": "Agronomy Department,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Qiu-Lan Ma",
                "org": "Modern Educational Technology Center,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Agronomy Department,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2006
    },
    "mEo65R8B": {
        "id": "mEo65R8B",
        "title": "Innovation in Educational Hardware of Multimedia Projection Equipment",
        "abstract": "To improve the efficiency and quality of teaching an innovation in educational hardware is presented. Two infrared receiver processors composed of photosensitive element,infrared reflective mirror rotated with changeless rate and infrared emitter as datum time are installed at the corner of multimedia projection screen to locate infrared pen used by teachers. Computer can be operated from multimedia projection screen and teachers are released from computer console to write on large screen and communicate with students at random.",
        "keywords": [
            "Large Screen",
            "Infrared",
            "Location",
            "Touch Screen",
            "Multimedia Projection"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,Anhui,,China"
            },
            {
                "name": "LI Jin-yao",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,Anhui,,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,Anhui,,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,Anhui,,China"
            }
        ],
        "venue": "Modern Educational Technology",
        "year": 2010
    },
    "4WcWhe3c": {
        "id": "4WcWhe3c",
        "title": "Thinking about Legislation of Human Gene Resources in China",
        "abstract": "Biological resources are very abundant in China.The advantages of human gene resources have already brought the attentions of the world.But the reality and actuality of legislation for the human gene resources protection in China isn't optimistic.The legislation of human gene resources should be strengthened and the measures about gene protection should be developed in China.",
        "keywords": [
            "protection",
            "human gene resources",
            "legislation of gene"
        ],
        "authors": [
            {
                "name": "HUANG Hui",
                "org": "Nanjing Medical University,Nanjing ,China"
            },
            {
                "name": "PAN Rui",
                "org": "Nanjing Medical University,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Nanjing Medical University,Nanjing ,China"
            },
            {
                "name": "LU Jian-hua",
                "org": "Nanjing Medical University,Nanjing ,China"
            }
        ],
        "venue": "R&D Management",
        "year": 2006
    },
    "Qx8kWpyr": {
        "id": "Qx8kWpyr",
        "title": "Positive linear relationship between productivity and diversity: evidence from the Eurasian Steppe",
        "abstract": "Summary 1. Understanding the productivity-diversity relationship (PDR) is a key issue in biodiversity-ecosystem functioning research, and has important implications for ecosystem management. Most studies have supported the predominance of a hump- shaped form of PDR in which species richness peaks at an intermediate level of productivity. However, this view has been challenged recently on several grounds. 2. Based on data from 854 field sites across the Inner Mongolia region of the Eurasian Steppe, we tested the form of PDR at different organizational levels (association type, vegetation type and biome) and multiple spatial scales (local, landscape and regional). 3. Our results showed that a positive linear, rather than hump-shaped, form was ubiquitous across all organizational levels and spatial scales examined. On the regional scale, this monotonic PDR pattern corresponded closely with the gradient in mean annual precipitation (MAP) and soil nitrogen. Increasing species dissimilarity with productivity could also contribute to the positive linear form of PDR. 4. Our results also indicated that grazing decreased both primary productivity and species richness but, intriguingly, not the form of PDR. 5. Synthesis and applications. This study provides the first direct test of the productivity- diversity relationship for the world's largest contiguous terrestrial biome - the Eurasian Steppe. The predominance of a positive linear relationship in this region defies the commonly held view that a unimodal form of PDR dominates terrestrial ecosystems, supported mainly by studies in Africa, Europe and North America. It suggests that precipitation has a greater control on the productivity-diversity relationship in the Eurasian Steppe than grasslands elsewhere. Also, the positive linear relationship is surprisingly robust to grazing. Our results provide new insight into the productivity- diversity relationship and have several implications for restoring degraded lands and understanding ecological consequences of climate change in the Eurasian Steppe.",
        "keywords": [
            "productivity-diversity relationship",
            "key-words : ecosystem management",
            "inner mongolia grassland",
            "species dissimilarity",
            "grazing land",
            "eurasian steppe",
            "spatial scale",
            "precipitation gradient",
            "ecosystem management",
            "primary production",
            "terrestrial ecosystems",
            "species richness",
            "climate change"
        ],
        "authors": [
            {
                "name": "YONGFEI BAI",
                "org": ""
            },
            {
                "name": "JIANGUO WU",
                "org": ""
            },
            {
                "name": "QINGMIN PAN",
                "org": ""
            },
            {
                "name": "JIANHUI HUANG",
                "org": ""
            },
            {
                "name": "QIBING WANG",
                "org": ""
            },
            {
                "name": "FUSHENG LI",
                "org": ""
            },
            {
                "name": "ALEXANDER BUYANTUYEV",
                "org": ""
            },
            {
                "name": "XINGGUO HAN",
                "org": ""
            }
        ],
        "venue": "Journal of Applied Ecology",
        "year": 2007
    },
    "k1BSzyBf": {
        "id": "k1BSzyBf",
        "title": "Total knee arthroplasty using trochlear groove as guide for position of femoral component in severe knee osteoarthritis.",
        "abstract": "Apart from transepicondylar axis, the native femoral sulcus was also reported to be used as a guide for the femoral component position in total knee arthroplasty (TKA). However, it was not shown in patients with severe knee osteoarthritis. This study was conducted to compare the position of trochlear groove in patients with and without osteoarthritis, and to assess whether trochlear groove could be used as a guide for position of femoral component in TKA for severe knee osteoarthritis.Total 50 severe knee osteoarthritis patients (Kellgren Lawrence grade 3 or 4) who underwent TKA were included. Meanwhile, 50 patients who underwent arthroscopic surgery without osteoarthritis were included as control. The distance from trochlear groove to the midpoint of a virtual anterior condyle osteotomy line (parallel to the posterior condyle line) (a-b) was recorded by radiological and surgical measurements. Midpoint of transepicondylar axis and trochlear groove were used as guide for placing prosthesis model in TKA, respectively. No-thumb test was performed to assess the patellar tracking. The position of femoral component was finally performed using trochlear groove as guide in TKA.Value of \"a-b\" was significantly different between osteoarthritic and control knees (P = 0.008). During the placement of prosthesis model, similar patellar tracking was detected between using midpoint of transepicondylar axis and trochlear groove as guide (P > 0.05). After placing femoral component using trochlear groove as guide, most patients obtained good patellofemoral congruence with pneumatic tourniquet inflated (n = 43) or deflated (n = 5), and good patellofemoral congruence was also obtained by lateral patellar retinaculum release in two patients.Despite the shifting of trochlear groove caused by severe knee osteoarthritis, trochlear groove can be used as a guide for position of femoral component, with equivalent patellar tracking compared with transepicondylar axis.",
        "keywords": [
            "Knee osteoarthritis",
            "Patellar tracking",
            "Prosthesis",
            "Total knee arthroplasty",
            "Trochlear groove"
        ],
        "authors": [
            {
                "name": "Gangyong Huang",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Jun Xia",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China. dr.xiajun@139.com."
            },
            {
                "name": "Siqun Wang",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Yibing Wei",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Feiyan Chen",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Jie Chen",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            },
            {
                "name": "Jingsheng Shi",
                "org": "Department of Orthopaedic Surgery, Huashan Hospital Fudan University, 12th Wulumuqi Middle Road, Shanghai, 200040, China."
            }
        ],
        "venue": "BMC surgery",
        "year": 2016
    },
    "amOdu1fR": {
        "id": "amOdu1fR",
        "title": "Analysis of embryo, cytoplasmic and maternal genetic correlations for seven essential amino acids in rapeseed meal (Brassica napus L.)",
        "abstract": "Genetic correlations of nutrient quality traits including lysine, methionine, leucine, isoleucine, phenylalanine, valine and threonine contents in rapeseed meal were analysed by the genetic model for quantitative traits of diploid plants using a diallel design with nine parents of Brassica napus L. These results indicated that the genetic correlations of embryo, cytoplasm and/or maternal plant have made different contribution to total genetic correlations of most pairwise nutrient quality traits. The genetic correlations among the amino acids in rapeseed meal were simultaneously controlled by genetic main correlations and genotype × environment (GE) interaction correlations, especially for the maternal dominance correlations. Most components of genetic main correlations and GE interaction correlations for the pairwise traits studied were significantly positive. Some of the pairwise traits had negative genetic correlations, especially between valine and other amino acid contents. Indirect selection for improving the quality traits of rapeseed meal could be expected in rape breeding according to the magnitude and direction of genetic correlation components. © 2011 Indian Academy of Sciences.",
        "keywords": [
            "amino acids contents",
            "genetic main correlations",
            "genotype × environment interaction correlations",
            "nutrient quality",
            "rapeseed meal",
            "quantitative trait",
            "embryos",
            "genotype environment interaction",
            "amino acid",
            "genetics",
            "genetic correlation"
        ],
        "authors": [
            {
                "name": "GUO LIN CHEN",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "JIAN GUO WU",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Murali Tottekkaad Variath",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "ZHONG WEI YANG",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "CHUN HAI SHI",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of Genetics",
        "year": 2011
    },
    "bjAXpYy8": {
        "id": "bjAXpYy8",
        "title": "Asymptotic Properties of W_n in the Stochastic Process",
        "abstract": "In this paper the asymptotic properties of W_n in the stochastic process is discussed.The conclusion that for fixed y,W_n(t,x,y) converges weakly to a Gaussian process is obtained.",
        "keywords": [
            "conditional distribution stochastic process asymptotic property"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Hunan College of Finance and Economics,Changsha,"
            }
        ],
        "venue": "Mathematical Theory and Applications",
        "year": 2006
    },
    "JAfk4ETk": {
        "id": "JAfk4ETk",
        "title": "Automatic Measurement of Blood Vessel Angles in Immunohistochemical Images of Liver Cancer.",
        "abstract": "This paper presents a method for automated measurement of vascular angle in immunohistochemical images of liver cancer. Firstly, Colour Deconvolution is used to conduct staining separation on a Hu0026E-stained immunohistochemical image, and then blood vessels are segmented using an improved Otsu algorithm. Then the standard SURF algorithm is used to select feature points of the image, and then these feature points are divided into two equal groups according to the distance between individual feature points and the far left (or right) feature point. Finally, a standard least squares method is used to fit two lines using the two groups of points. When the linear deviation of the fitting result based on the two groups of feature points is significant, it is necessary to adjust the belonging of the points of the two groups, and then the two sets are fitted again respectively till the correlation coefficients of the two fitted lines are greater than the predefined threshold, meaning that the measurement of the blood vessel angle in the immunohistochemical map is completed. Compared with the experts’ results, our proposed technique results in better accuracy. It is worthy to point out that, to our knowledge, our system is the first one that conducts automated measurement of blood vessel angle of immunohistochemistry.",
        "keywords": "",
        "authors": [
            {
                "name": "Hongbin Zhang",
                "org": "Nantong University"
            },
            {
                "name": "Kun Zhang",
                "org": "Nantong University"
            },
            {
                "name": "Li Chen",
                "org": "Nantong University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Nantong University"
            },
            {
                "name": "Peijian Zhang",
                "org": "Nantong University"
            },
            {
                "name": "Huiyu Zhou",
                "org": ""
            }
        ],
        "venue": "LSMS/ICSEE",
        "year": 2017
    },
    "AP3lxETy": {
        "id": "AP3lxETy",
        "title": "GP73 expression is activated and correlated with IFN activation during HCV infection.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Xuewu",
                "org": ""
            },
            {
                "name": "Zhu Chengliang",
                "org": ""
            },
            {
                "name": "Wang Tianci",
                "org": ""
            },
            {
                "name": "Jiang Hui",
                "org": ""
            },
            {
                "name": "Ren Yahui",
                "org": ""
            },
            {
                "name": "Zhang Qi",
                "org": ""
            },
            {
                "name": "Wu Kailang",
                "org": ""
            },
            {
                "name": "Liu Fang",
                "org": ""
            },
            {
                "name": "Liu Yingle",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2017
    },
    "1Fkxw3VV": {
        "id": "1Fkxw3VV",
        "title": "Regulation of the <Emphasis Type=\"Italic\">Caulobacter crescentus rpoN</Emphasis> gene and function of the purified σ<Superscript>54</Superscript> in flagellar gene transcription",
        "abstract": "The sequential transcription of flagellar (fla) genes in the Caulobacter crescentus cell cycle is controlled by the organization of these genes in a regulatory hierarchy of four levels (I-IV). Level III and level IV genes at the bottom of the hierarchy are dependent on level II genes and are transcribed late in the cell cycle from sigma 54-dependent promoters. To study the regulation of genes at levels III and IV, we have isolated and sequenced the rpoN gene in order to analyze its expression, purified the rpoN gene product, and examined the role of the RpoN protein in initiation of transcription from sigma 54-dependent promoters. We report here epistasis experiments that show rpoN is required for transcription of level III genes, but that the expression of the rpoN gene itself is not dependent on any of the fla genes examined; these results place rpoN at level II near the top of the hierarchy. Consistent with this conclusion were nuclease S1 assays that mapped the rpoN transcription start site and identified a sequence centered at -24, GTTA/TACCA/TT, which is similar to the core consensus sequence of the level IIB fliF, fliL, and fliQ promoters. We purified the full-length rpoN gene product to near homogeneity and demonstrated that the RpoN protein is required for transcription from the well-characterized sigma 54-dependent glnAp2 promoter of Escherichia coli and specifically recognizes the level III flbG gene promoter of C. crescentus. These last results confirm that rpoN encodes the C. crescentus sigma 54 factor and opens the way for the biochemical analysis of transcriptional regulation of level III and IV fla genes.",
        "keywords": [
            "rpoN regulation",
            " RpoN purification in vitro transcription"
        ],
        "authors": [
            {
                "name": "D. Karl Anderson",
                "org": "Department of Molecular Biology,Princeton University,Princeton,USA"
            },
            {
                "name": "Noriko Ohta",
                "org": "Department of Molecular Biology,Princeton University,Princeton,USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Molecular Biology,Princeton University,Princeton,USA"
            },
            {
                "name": "Austin Newton",
                "org": "Department of Molecular Biology,Princeton University,Princeton,USA"
            }
        ],
        "venue": "Molecular and General Genetics MGG",
        "year": 1995
    },
    "3JnkwZgP": {
        "id": "3JnkwZgP",
        "title": "Asprellcosides B of Ilex asprella Inhibits Influenza A Virus Infection by Blocking the Hemagglutinin- Mediated Membrane Fusion",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wen Zhang",
                "org": ""
            },
            {
                "name": "Si-Tai Chen",
                "org": ""
            },
            {
                "name": "Qiu-Yan He",
                "org": ""
            },
            {
                "name": "Li-Quan Huang",
                "org": ""
            },
            {
                "name": "Xiong Li",
                "org": ""
            },
            {
                "name": "Xiao-Ping Lai",
                "org": ""
            },
            {
                "name": "Shao-Feng Zhan",
                "org": ""
            },
            {
                "name": "Hui-Ting Huang",
                "org": ""
            },
            {
                "name": "Xiao-Hong Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Geng Li",
                "org": ""
            }
        ],
        "venue": "Frontiers in Microbiology",
        "year": 2019
    },
    "fypSFaZ7": {
        "id": "fypSFaZ7",
        "title": "Geographical distribution pattern and climate characteristics of adaptation for Kobresia in China",
        "abstract": "Aims Our objective was to determine the distribution pattern and climate characteristics of Kobresia in China.Methods Distribution information was collected from the literature and floras.Climate information was col-lected from China's meteorological stations.ArcGIS software and cluster analysis methods in SPSS software were applied to analyze data.Important findings Kobresia is mainly distributed on the Tibetan Plateau and in northern China.Fifteen species have wide distributions,and ten have disjunct distributions.The ranges of elevation,latitude and longitude of Ko-bresia's distribution are 1 400-5 000 m,23-46°N and 81-112°E,respectively.Mean values of climatic factors are Holdridge annual biotemperature of 4-19℃,annual mean air temperature of 0-20℃,annual mean maximum and minimum air temperatures of 7-28 and-6-16℃,respectively,extreme high and low air temperatures of 25-40 and-37-0℃,respectively,mean air temperature in January and July of-14-13 and 11-24℃,respec-tively,highest air temperature in January and July of-7-23 and 18-30℃,respectively,lowest air temperature in January and July of-22-7 and 5-20℃,respectively,mean air temperature in spring,summer,autumn and winter of-4-19,9-23,6-21 and-11-15℃,respectively,Kira warmth index and coldness index of 23-159 and-36-0 ℃,respectively,annual precipitation of 154-1 500 mm,precipitation in spring,summer,autumn and winter of 19-135,53-662,48-545 and 5-92 mm,respectively,Holdridge annual potential evapotranspiration of 261-1 100 mm,Thornthwaite annual potential evapotranspiration,aridity index and humidity index of 399-895 mm,167-786 and 179-816,respectively,and sunshine duration from April to October of 990-2 100 h.Generally,there is a high richness of Kobresia under lower or medium mean value of thermal factors,medium mean value of pre-cipitation,aridity or humidity or higher mean value of sunshine duration.As for extreme value of climatic factors,the range for minimum-maximum value of annual air temperature,the range for minimum value of extreme low-est and maximum value of extreme highest air temperature,air temperature range for minimum value in coldest and maximum value in hottest month,air temperature range for minimum value in winter and maximum value in summer are-6-21,-12-28,-48-42,-32-33 and-20-25℃,respectively,and the ranges for minimum-maximum values of annual precipitation,aridity index and sunshine duration from April to October are 15-1 800 mm,7-890 and 701-2 300 h,respectively.There is a high species richness of Kobresia under lower and medium extreme values of thermal factors,medium extreme value of precipitation,aridity,and higher extreme value of sunshine duration.The results suggest that Kobresia in China is primarily adapted to microthermal subhumid or mesother-mal humid climatic types.",
        "keywords": [
            "air temperature",
            "geographical distribution",
            "Kobresia",
            "climatic factor"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": " Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "ZHOU Qiao-Fu",
                "org": " Chinese Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Plant Ecology",
        "year": 2012
    },
    "7HMxN9fu": {
        "id": "7HMxN9fu",
        "title": "Application of near-infrared reflectance spectroscopy to evaluate the lutein and β-carotene in Chinese kale",
        "abstract": "There are wide ranges of lutein and β-carotene in Chinese kale. This work assessed the capability of near-infrared reflectance spectroscopy (NIRS) to predict the contents of lutein and β-carotene in Chinese kale against HPLC analysis. Compared to other regression methods, the regression of modified partial least squares with math treatments of 2,4,4,1 (where the first number of 2 represents the second derivative of log 1/ R , the second of 4 is the gap in data points over which the derivative is calculated, the third and fourth numbers refer to the number of data points used in the first and second smoothing, respectively) showed the best results. The calibration equations of lutein and β-carotene were characterized by the coefficients of determination (RSQ) of 0.983 and 0.982 and standard error of 0.056 and 0.131 mg g −1 DW, respectively. In cross-validation, high 1 minus variance ratio (1 − VR) of 0.955 and 0.966 and standard error of 0.092 and 0.179 mg g −1 DW for lutein and β-carotene were obtained, respectively. In external validations, the RSQ were 0.926 and 0.875 with standard error of 0.131 and 0.367 mg g −1 DW, respectively. These results showed that NIRS could be used for the determination of carotenoids in Chinese kale. Abbreviations Bias difference of means HPLC high-performance liquid chromatography MPLS modified partial least squares NIRS near-infrared reflectance spectroscopy PCR principal component regression PLS partial least squares RPD ratio of the standard deviation to SEP RSQ coefficients of determination SEC standard error of calibration SECV standard error of cross-validation SEP standard error of performance S.D. standard deviation 1 − VR coefficient of determination in cross-validation Keywords Chinese kale Brassica oleracea alboglabra Near-infrared reflectance spectroscopy (NIRS) Carotenoid extraction method Lutein β-Carotene Food composition Food analysis 1 Introduction Chinese kale ( Brassica oleracea alboglabra), also known as Chinese broccoli, Chinese flowering broccoli, kailan ( http://www.worldcrops.org/crops/Chinese-broccoli.cfm ( Anon, 2008b ); http://www.cherryfarms.co.uk/kailan.asp ( Anon, 2008d )), is a source of important phytonutrients such as lutein and β-carotene ( http://www.cherryfarms.co.uk/kailan.asp ; Kopsell et al., 2004 ) and commonly consumed as a healthy vegetable in south Asia especially popular in south China. Both lutein and β-carotene ( Fig. 1 ), well-known carotenoids, are widely present in vegetables and fruits: the former is the most important precursors of provitamin A; the latter can increase macular pigment concentration in eyes and may improve visual function ( Krinsky, 2001 ). Recent research has demonstrated that lutein and β-carotene can act as powerful antioxidants and to help guard against aging, cancers and diseases ( http://www.luteininfo.com ( Anon, 2008c ); http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-betacarotene.html ( Anon, 2008a )). It is very important for nutritionists and researchers to obtain the information on lutein and β-carotene content in vegetables and fruits. The common methods for determining of lutein and β-carotene, based on solvent extraction followed by HPLC analysis, usually involve high cost, labor and time input, and specialized technicians. In addition, the volatile, degradable or hazardous chemicals used in the extraction and HPLC analysis can imply some instability of results and health risk on human health and environment. To date, near-infrared reflectance spectroscopy (NIRS), widely used as a fast, accurate and non-pollution method for qualitative and quantitative analysis in food and pharmaceutical fields for the last 30 years ( Cen and He, 2007; Roggo et al., 2007 ), have been well recommended for the determination of total carotenoids in carrot fruit ( Schulz et al., 1998 ) and wheat seeds ( Atienza et al., 2005 ) and especially some individual carotenoids such as lycopene and lutein in tomato products ( Pedro and Ferreira, 2005 ), zeaxanthin and lutein in maize seeds ( Brenna and Berardo, 2004; Berardo et al., 2004 ); however, there is very limited correlative research in the non-seed plant tissues. Recently, our research group has succeeded in determining seed traits of crops by NIRS ( Wu et al., 2002, 2006; Wu and Shi, 2003, 2004, 2007; Lin et al., 2005 ). The purpose of this work was to test the potential of NIRS for simultaneously predicting the lutein and β-carotene contents in the non-seed tissues of Chinese kale and to provide a simple, rapid and accurate analysis method via NIRS technique. 2 Materials and methods 2.1 Samples Chinese kale varieties with high variation of agronomy traits were planted under different seasons, soil types and fertilizer conditions in Zhejiang province over a period of 2 years (2004–2005). Edible tender and succulent plant parts comprising one or several stout and chunky stems accompanied with small and loose terminal floral buds, ∼6–7 pieces of flat and broad leaves, and ∼2–3 lateral branches were separately or mix harvested at the very beginning of flowering, and frozen immediately in liquid nitrogen. After being lyophilized by a freeze dryer (Vir Tis, USA), ground into powder by a WK-200B miller (Dongwan, China) and filtrated with 0.25 mm screen, the total freeze-dried powder of 151 samples was stored in a desiccator at −20 °C prior to HPLC and NIRS analysis. 2.2 Extraction of lutein and β-carotene The extraction of lutein and β-carotene were conducted according to the protocol of Gilmore and Yamamoto (1991) with modifications. About 0.1 g freeze-dried powder was weighed into 10 ml tubes and extracted with 4 ml of acetone for 30 min in an ultrasonic cleaning bath (SK5200H, Kudos, China) operating at 59 kHz frequency. The supernatants were decanted and stored on ice, and the pellets were re-extracted twice with 3 ml of acetone for 10 min under same conditions. Three supernatants were combined and made up to a final volume of 10 ml with acetone. About 1.5 ml of extracts was filtrated by a 0.2-μm organic film and kept at 4 °C prior to HPLC analysis. All procedures were performed under dim light condition and at room temperature. 2.3 HPLC analysis The HPLC analysis was conducted according to the protocol of Gilmore and Yamamoto (1991) with modifications. Ten microlitres of extracts were analyzed in a Shimadzu HPLC system (LC-10AT pump, CTO-10A column oven, SCL-10A vp system controller, Shimadzu, Kyoto, Japan) consisting of a UV-VIS detector (SPD-10A) set at 440 nm and a spherisorb C18 column (250 mm × 4.6 mm, 5 μm; Waters, USA). The mobile phase A was acetonitrile:methanol:0.05 mol/l Tris–HCl (72:8:3) and B was methanol:hexane (5:1). The elution procedure is as follows: 100% A for first 4 min, then in a linear gradient from 0% to 100% B in 2.5 min and constant 100% B for 13.5 min, then equilibrated with 100% A for 5 min prior to the injection of next sample. The flow rate was 1.5 ml min −1 at room temperature. HPLC grade of standards of lutein (Sigma–Aldrich, USA) and β-carotene (Sigma–Aldrich, USA) were utilized for the quality and quantity analysis. 2.4 NIRS analysis A total of 151 samples were scanned on a NIR Systems model 5000 monochromator (NIR Systems Inc., Silver Spring, MD, USA). About 0.5 g freeze-dried powder was loaded in a small ring cup with 20 mm i.d., and reflectance spectra (log 1/ R ) from 1100 to 2500 nm were recorded at 2 nm intervals. Each sample was subsequently scanned three times and the average spectrum was collected. 2.5 Calibration and validation procedures WINISI (version 1.04) software (Infrasoft International, Port Matila, PA, USA) was used to collect spectra, develop equations and evaluate calibration performance. Principal component regression (PCR), partial least squares (PLS) and modified PLS (MPLS) were used to analyze the regression effect. Different math treatments were applied during equation development in MPLS, e.g. 2,4,4,1, where the first number indicates the order of the derivative (0 represents no derivative, 1 represents the first derivative and 2 represents the second derivative of log 1/ R ), the second is the gap in data points over which the derivative is calculated, the third and fourth numbers refer to the number of data points used in the first and second smoothing, respectively. The most significant wave regions for NIRS estimation of lutein and β-carotene were studied by calculating the correlation coefficients between the carotenoids values and the spectral data (second derivative, scatter corrected). 3 Results and discussion 3.1 Lutein and β-carotene composition in the calibration set The composition of lutein and β-carotene in non-seed tissues of 151 Chinese kale samples are listed in Table 1 . The calibration set with 122 samples was randomly selected from original set and the rest 29 samples were grouped as external validation set. The ranges of lutein and β-carotene were from 0.044 to 2.223 mg g −1 DW and 0.006 to 4.852 mg g −1 DW, respectively. Wide variations were observed for lutein and β-carotene among samples, which was mainly due to the incorporation of samples from different varieties, organs, and growth conditions. Obviously, due to the limitation of sample number and the relative diversity of carotenoid content, one or two obviously blank distributions of both lutein and β-carotene in the sample set were observed ( Fig. 2 ). Furthermore, there are remarkable bimodal natures of lutein distribution at range of 0.04–0.3 mg g −1 DW and of 0.3–1.7 mg g −1 DW in sample set. For β-carotene, the bimodal nature of distribution occurred at range of 0.01–0.6 mg g −1 DW and 1.0–3.0 mg g −1 DW, respectively. The first peak is primarily related with the distribution of different plant parts of Chinese kale, and the second peak is mainly originated from the different varieties. Both of the blank and bimodal nature indicated that more different sample should be continuously research collected in the future experiments. 3.2 NIR spectra analysis NIR spectra for all samples in calibration set were shown in Fig. 3 and the results showed that a considerable contribution was due to diversity among samples in a wide wavelength range (1700–2400 nm), a typical near-infrared range. Indeed, this range had been used to measure maize pigments by NIRS method ( Brenna and Berardo, 2004 ). Although NIRS procedure was inherently empirical, its underlying analytical basis could be explored by identifying the spectral regions associated with the analyzed trait ( Roberts et al., 1997 ). According to the correlation of structural characteristics and NIR spectra ( Cen and He, 2007 ), it should be quite similar for NIR spectra between lutein and β-carotene in theory. However, some differences were also revealed in the wavelength range of 1452–2382 nm ( Fig. 4 ). The highest correlated wavelengths (absolute value of higher than 0.9) were 2176, 2336, 1770 and 2066 nm for lutein and 2176, 2336 and 1770 nm for β-carotene, respectively. Most of them belong to the range of spectral regions associated to lutein (1158–2378 nm) found by Brenna and Berardo (2004) in the analysis of maize seeds. Therefore, the major contribution for developing the calibration model for lutein and β-carotene was the whole NIR spectral range. The most significant wavelength for lutein content was 2176 nm, which does not confirm the previous result of Brenna and Berardo (2004) , who found 1168 nm as the most relevant wavelength for lutein determination in maize seed. 3.3 NIR calibration model As shown in Table 2 , low SEC and high RSQ in calibration set for lutein were obtained both in PLS and MPLS regressions when compared with PCR regression. In cross-validation set, higher S.D. of the reference data to SECV ratio (S.D./SECV) of 4.854 and 4.728 and 1 − VR (1 minus variance ratio) of 0.958 and 0.955 were also obtained in these two regressions, respectively. For β-carotene, same phenomena emerged and low SEC (0.126 and 0.131 mg g −1 DW) and high RSQ (0.982), S.D./SECV (5.471 and 5.430) and 1 − VR (0.967 and 0.966) were obtained in PLS and MPLS regressions. There were some differences in NIR calibration model for both lutein and β-carotene between MPLS and PLS regression; however, the use of principal component regression gave less accurate results than those obtained from MPLS and PLS regression. The equations in PLS and MPLS regression for lutein and β-carotene showed high RSQ values, and low standard errors in calibration and cross-validation. It implied that a reliable estimation of lutein and β-carotene could be obtained by NIRS with both PLS and MPLS regressions. Moreover, considering the algorithm of MPLS, this method was selected to employ the subsequent tests. The good relationships of NIRS predicted versus HPLC data for lutein and β-carotene were shown in Fig. 5 in calibration set under MPLS. A group of samples covering a wider range for NIRS calibration could probably result in much more accurate calibration equations ( Velasco and Becker, 1998 ). In the present study, the calibration set included samples collected from different organs and varieties which were cultivated in greenhouse or field at different locations and cultured with different fertilizers during different years. The good results obtained in the calibration set for both lutein and β-carotene could be explained by this large variability among analyzed samples. 3.4 Math treatment in MPLS The results in Table 3 show that the second derivative of the spectra (2,4,4,1) in lutein could give the better results than those obtained from another second derivative (2,8,8,1). The lowest SEC (0.131 mg g −1 DW) and highest RSQ (0.982) of lutein were obtained by transforming the raw optical data into the second derivative (2,4,4,1) prior to calibration. Furthermore, the highest S.D./SECV of 4.728 and 1 − VR of 0.955 were also obtained in 2,4,4,1. Like the calibration for lutein, the second derivative method (2,4,4,1) could also be selected to develop the calibration equation for β-carotene. For the NIRS analysis of lutein and β-carotene, high RSQ of 0.97 and 0.82 for lutein and β-carotene in maize seeds had been reported by Brenna and Berardo (2004) in MPLS with 2,8,6. However, significant improved results of higher values of RSQ for lutein (0.983) and β-carotene (0.982) in MPLS with 2,4,4,1 were obtained in present experiment. 3.5 External validation statistics in MPLS The external validation statistics for lutein and β-carotene are shown in Table 4 . Significant correlation of the plotting reference values versus predicted values could be found with high RSQ of 0.926 and 0.875 for lutein and β-carotene, respectively, confirmed also by the ratio of the standard deviation to SEP (RPD) of 3.641 and 2.787, the bias values of −0.009 and 0.014 and a slope of 0.985 and 0.964 for lutein and β-carotene, respectively. 4 Conclusions Against the results of HPLC, the regression of MPLS with math treatment (2,4,4,1) showed an excellent estimation ability on the quantitative analysis of lutein and β-carotene in Chinese kale. For the first time, NIRS analysis has demonstrated that it can be used to estimate the composition of lutein and β-carotene in freeze-dried samples. The NIRS equations of lutein and β-carotene developed in the present work represent only a first step, and they should be tested, expanded, and improved in future by adding other special samples of Chinese kale and other vegetables. Acknowledgements The project is supported by the Science and Technology Office of Zhejiang Province (No. 2007C22016) and 151 Foundation for the Talents of Zhejiang Province and we thank Dr. K.B. Kumar, Professor Z.H. Xu and Mr. Tottekkaad for improving English for this manuscript. References Anon, 2008a Anon, 2008a. β-Carotene. http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-betacarotene.html (retrieved 23.08.2007). Anon, 2008b Anon, 2008b. Chinese broccoli Brassica oleracea . http://www.worldcrops.org/crops/Chinese-broccoli.cfm (retrieved 23.08. 2007). Anon, 2008c Anon, 2008c. How lutein supports human health. http://www.luteininfo.com (retrieved 23.08.2007). Anon, 2008d Anon, 2008d. Products—Kai Lan ( Brassica alboglabra). http://www.cherryfarms.co.uk/kailan.asp (retrieved 23.08.2007). Atienza et al., 2005 S.G. Atienza C.M. Avila M.C. Ramirez A. Martin Application of near infrared reflectance spectroscopy to the determination of carotenoid content in tritordeum for breeding purposes Aust. J. Agric. Res. 56 2005 85 89 Berardo et al., 2004 N. Berardo O.V. Brenna A. Amato P. Valoti V. Pisacane M. Motto Carotenoids concentration among maize genotypes measured by near infrared reflectance spectroscopy (NIRS) Innovat. Food Sci. Emerg. Tech. 5 2004 393 398 Brenna and Berardo, 2004 O.V. Brenna N. Berardo Application of near-infrared reflectance spectroscopy (NIRS) to the evaluation of carotenoids content in maize J. Agric. Food Chem. 52 2004 5577 5582 Cen and He, 2007 H. Cen Y. He Theory and application of near infrared reflectance spectroscopy in determination of food quality Trends Food Sci. Technol. 18 2007 72 83 Gilmore and Yamamoto, 1991 A.M. Gilmore H.Y. Yamamoto Resolution of lutein and zeaxanthin using a nonendcapped, lightly carbon-loaded C18 high performance liquid chromatographic column J. Chromatogr. 543 1991 137 145 Kopsell et al., 2004 D.A. Kopsell D.E. Kopsell M.G. Lefsrud J. Curran-Celentano L.E. Dukach Variation in lutein, β-carotene, and chlorophyll concentrations among Brassica oleracea cultigens and seasons HortScience 39 2004 361 364 Krinsky, 2001 N.I. Krinsky Carotenoids as antioxidants Nutrition 17 2001 815 817 Lin et al., 2005 J. Lin C. Shi M. Wu J. Wu Analysis of genetic effects for cooking quality traits of japonica rice across environments Plant Sci. 168 2005 1501 1506 Pedro and Ferreira, 2005 A.M.K. Pedro M.M.C. Ferreira Nondestructive determination of solids and carotenoids in tomato products by near-infrared spectroscopy and multivariate calibration Anal. Chem. 77 2005 2505 2511 Roberts et al., 1997 C.A. Roberts R.E. Joost G.E. Rottinghaus Quantification of ergovaline in tall fescue by near infrared reflectance spectroscopy Crop Sci. 37 1997 281 284 Roggo et al., 2007 Y. Roggo P. Chalus L. Maurer C. Lema-Martinez A. Edmond N. Jent A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies J. Pharm. Biomed. Anal. 44 2007 683 700 Schulz et al., 1998 H. Schulz H.H. Drews R. Quilitzsch H. Krüger Application of near infrared spectroscopy for the quantification of quality parameters in selected vegetables and essential oil plants J. Near Infrared Spectrosc. 6 1998 125 130 Velasco and Becker, 1998 L. Velasco H.C. Becker Estimating the fatty acid composition of the oil in intactseed rapeseed ( Brassica napus L.) by near infrared reflectance spectroscopy Euphytica 101 1998 221 230 Wu and Shi, 2003 J.G. Wu C.H. Shi The applications of near-infrared reflectance spectroscopy in plant breeding and germplasm research J. Plant Genet. Resour. 4 2003 68 72 Wu and Shi, 2004 J.G. Wu C.H. Shi Prediction of grain weight, brown rice weight and amylose content in single rice grains using near-infrared reflectance spectroscopy Field Crops Res. 87 2004 13 21 Wu and Shi, 2007 J.G. Wu C.H. Shi Calibration model optimization for rice cooking characteristics by near infrared reflectance spectroscopy (NIRS) Food Chem. 103 2007 1054 1061 Wu et al., 2002 J.G. Wu C.H. Shi X. Zhang Estimating the amino acid composition in milled rice by near-infrared reflectance spectroscopy Field Crops Res. 75 2002 1 7 Wu et al., 2006 J.G. Wu C.H. Shi H.Z. Zhang Study on developing calibration model of fat acid composition in intact rapeseed by near infrared reflectance spectroscopy Spectrosc. Spect. Anal. 26 2006 259 262",
        "keywords": [
            "β-carotene",
            "brassica oleracea alboglabra",
            "carotenoid extraction method",
            "chinese kale",
            "food analysis",
            "food composition",
            "lutein",
            "near-infrared reflectance spectroscopy (nirs)",
            "external validity",
            "chemical composition",
            "xanthophyll",
            "analytical methods",
            "cross validation",
            "coefficient of determination"
        ],
        "authors": [
            {
                "name": "Xinjuan Chen",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Shengjun Zhou",
                "org": "Institute of Vegetable Science, Zhejiang Academy of Agriculture Science, Hangzhou 310021, China"
            },
            {
                "name": "Yuejian Yang",
                "org": "Institute of Vegetable Science, Zhejiang Academy of Agriculture Science, Hangzhou 310021, China"
            },
            {
                "name": "Xiaolei Ni",
                "org": "College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Jing Yang",
                "org": "College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Zhujun Zhu",
                "org": ""
            },
            {
                "name": "Chunhai Shi",
                "org": ""
            }
        ],
        "venue": "Journal of Food Composition and Analysis",
        "year": 2009
    },
    "ClDuKyyA": {
        "id": "ClDuKyyA",
        "title": "Affection of Rice dwarf virus on three phytohormones and transcriptional level of related genes in infected rice",
        "abstract": "HPLC and Real-time PCR experiments were conducted for investigating the dynamics of GA3,IAA and ABA in response to Rice dwarf virus (RDV) infection on rice variety Yixiang 2292 (Oryza sativa L. ssp. indica cv. Yixiang 2292). The results showed that GA3 content was significantly lower in RDV infected rice than that in healthy plants,being 6.28 and 5.92 times lower at 1 and 10 days after symptom appearance,respectively. The content of IAA in RDV infected rice plants was fluctuated,but always lower than that in healthy one. The lowest point was at 10th day after symptom appearance,which was 3.58 times lower than that in healthy plants. In contrast to GA3 and IAA,the level of ABA in infected rice plants was always higher,the most significant increase was at 1 and 13 days after symptom appearance,2.29 and 2.84 times more in the diseased plants than in control. Real-time PCR experiments were conducted to investigate expression change of hormone regulated genes. The results showed that oxidoreductase,a GA3 related gene decreased after RDV infection. Cullin-1 and P-glycoprotein 1 genes involved in the metabolism of IAA and ABA,were up-regulated to various extents. All these indicated that the symptom induced by RDV infection might be the result of phytohormones disruption.",
        "keywords": [
            "Rice dwarf virus",
            "auxin (IAA)",
            "abscisic acid (ABA)",
            "phytohormones",
            "gibberellic (GA3)"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            },
            {
                "name": "WANG Ping",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            },
            {
                "name": "XIE Li-yan",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            },
            {
                "name": "LIN Qi-ying",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            },
            {
                "name": "WU Zu-jian",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            },
            {
                "name": "XIE Lian-hui",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University ,Key Laboratory of Plant Virology of Fujian Province,Fuzhou ,China"
            }
        ],
        "venue": "Acta Phytopathologica Sinica",
        "year": 2010
    },
    "qJoWLcr6": {
        "id": "qJoWLcr6",
        "title": "Application of Mathematic Methods in Economics",
        "abstract": "With the development of economy, mathematical method is widely used in economy.At present,it plays an important role in economy.Process of mathematics in economy shall be handled dialectically, which can not be deified or negated wholly.",
        "keywords": [
            "mathematic method",
            "economy",
            "correlation"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Hunan College of Finance and Economics, Changsha Hunan "
            }
        ],
        "venue": "",
        "year": 2005
    },
    "Vz24waJe": {
        "id": "Vz24waJe",
        "title": "An ILP Algorithm that Combines Top-down and Bottom-up Methods",
        "abstract": "Inductive Logic Programming (ILP) is an important branch of machine learning.Given a set of examples and background knowledge,ILP studies how to construct a logic program consistent with these data.The logic program consists of some first-order clauses.This paper describes a new algorithm which integrates some advantage aspects of current ILP methods.In particular,it combines a bottom-up method similar to FOIL with a top-down method similar to GOLEM.It also includes predicate invention and recursive program learning.Contrasting experiments demonstrate the advantages of this method.",
        "keywords": [
            "inductive logic programming",
            "bottom-up",
            "first-order clause",
            "top-down"
        ],
        "authors": [
            {
                "name": "Xu Zhongwei",
                "org": "Key Laboratory of Intelligence Computing and Signal Processing, Ministry of Education,Anhui University,Hefei ;Dept. of Computer Science,Shandong University at Weihai,Weihai,Shandong "
            },
            {
                "name": "Li Wei",
                "org": "Key Laboratory of Intelligence Computing and Signal Processing, Ministry of Education,Anhui University,Hefei "
            },
            {
                "name": "Song Jie",
                "org": "Key Laboratory of Intelligence Computing and Signal Processing, Ministry of Education,Anhui University,Hefei "
            },
            {
                "name": "Wu Jianguo",
                "org": "Key Laboratory of Intelligence Computing and Signal Processing, Ministry of Education,Anhui University,Hefei "
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2006
    },
    "BWGbDJsq": {
        "id": "BWGbDJsq",
        "title": "Integrating animal manure-based bioenergy production with invasive species control: A case study at Tongren Pig Farm in China",
        "abstract": "Integrated approach and bioresource engineering are often required to deal with multiple and interactive environmental problems for sustainable development at local and regional scales. Pig farming has flourished with fast growing economy and increasing human demands for meat in China. Water hyacinth (Eichhornia crassipes), a noxious invasive species, has encroached into most of the local rivers and lakes. Both the wastes from the booming pig farms as well as the massive plant materials of water hyacinth have caused a range of serious ecological and environmental problems. Here we present an integrated sustainable, ecological and experimental study that was designed to deal with these two problems simultaneously. Our experimental results showed that the mixtures of water hyacinth with pig manure consistently had much higher biogas production than pig manure alone, and that the highest biogas production was achieved when 15% of the fermentation substrates were water hyacinth. Our analysis further revealed that the changing C/N ratio and the lignin content in the fermentation feedstock due to the addition of water hyacinth might be two important factors affecting the biogas production. We also found that the solar-powered water-heating unit significantly increased the biogas production (especially in winter time). Overall, the project proved to be successful ecologically and socially. Through such an integrated approach and bioresource engineering, wastes are treated, energy is harvested, and the environment is protected. (C) 2010 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Biomass energy",
            "Biogas production",
            "Pig manure fermentation",
            "Water hyacinth (Eichhornia crassipes)",
            "Solar energy",
            "Integrated approach",
            "Sustainable development"
        ],
        "authors": [
            {
                "name": "Jianbo Lu",
                "org": "Zhejiang Univ, Coll Life Sci, Inst Agroecol & Ecol Engn, Hangzhou 310058, Zhejiang, Peoples R China"
            },
            {
                "name": "Lei Zhu",
                "org": "Zhejiang Univ, Coll Life Sci, Inst Agroecol & Ecol Engn, Hangzhou 310058, Zhejiang, Peoples R China"
            },
            {
                "name": "Guoliang Hu",
                "org": "Agr Bur, Rural Energy Sect, Haining City 314400, Zhejiang, Peoples R China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang Univ, Coll Life Sci, Inst Agroecol & Ecol Engn, Hangzhou 310058, Zhejiang, Peoples R China"
            }
        ],
        "venue": "BIOMASS & BIOENERGY",
        "year": 2010
    },
    "50KlH2pg": {
        "id": "50KlH2pg",
        "title": "Determination of Silicon in Gasoline by Inductively Coupled Plasma Optical Emission Spectroscopy",
        "abstract": "The samples were incinerated by high temperature,and treated by nitric acid.The content of silicon in the gasoline was determined by inductively coupled plasma optical emission spectroscopy(ICP-OES).There was a good linear relationship for silicon content between 0 and 10μg/mL with r=0.9999,and RSD was from 0.980% to 13.620%,and recovery was in the range of 95.0%—111.6%.",
        "keywords": [
            "Silicon",
            "Gasoline",
            "Inductively Coupled Plasma Optical Emission Spectroscopy"
        ],
        "authors": [
            {
                "name": "CHEN Xin-Yue",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "WU Jian-Guo",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "LIU Ming-Yang",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "SUN Yan-Wei",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "YU Xiao-Zhan",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "ZHANG Ying-Yan",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Spectroscopy Laboratory",
        "year": 2011
    },
    "HIgeImsh": {
        "id": "HIgeImsh",
        "title": "Job satisfaction of the township health workers and the affecting factors",
        "abstract": "Objective To investigate the job satisfaction of township health workers and to analyze the main affecting factors,thereby,to provide some references about improving the quality of township health service and developing the primary health service.Methods Group random stratification sampling selected,a total of 234 medical staff in 8 rural township hospitals of 2 counties of Lianyungang was interviewed before the analysis of the questionnaire results.Factor analysis and Logistic regression analysis were used to find out the main affecting factors.Results 215 valid questionnaires had been collected.The general degree of satisfaction was 2.51.The main factors affecting job satisfaction were management and human system,working environment and salary.The main sociological affecting factors were educational background,administrative duties and professional titles.Conclusion Rural township hospitals should enhance the satisfaction by improving the human system,strengthening the infrastructure construction,providing higher salaries and so on.",
        "keywords": [
            "job satisfaction",
            "factor",
            "rural township hospital"
        ],
        "authors": [
            {
                "name": "HE Jia-jia",
                "org": "School of Health Policy﹠Management,Nanjing Medical University,Jiangsu ,China"
            },
            {
                "name": "LIN Zhen-ping",
                "org": "School of Health Policy﹠Management,Nanjing Medical University,Jiangsu ,China"
            },
            {
                "name": "ZHAO Liang",
                "org": "School of Health Policy﹠Management,Nanjing Medical University,Jiangsu ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Health Policy﹠Management,Nanjing Medical University,Jiangsu ,China"
            }
        ],
        "venue": "Chinese Rural Health Service Administration",
        "year": 2012
    },
    "mlfK8PgQ": {
        "id": "mlfK8PgQ",
        "title": "Potential effects of climate change in future on the distributions of 7 desert plants in China",
        "abstract": "It is crucial to know the effects of climate change on the distribution of species for the conservation of biodiversity under the climate change.Many studies have lacked of using long term climate change scenarious and many climatical variables when analyzing the effects of climate change on the distribution of species,so there are high uncertainness for the effects of climate change on the distribution of species.There are about 30 000 high plants species and 600 desert plants species in China,while the effects of climate change on the distribution of the plants are not clear.To know the effects of climate change on the distribution of desert plants in China,the effects of climate change on the distributions of Stilpnolepis centiflora,Reaumuria soongorica,Ajania fruticulosa,Cancrinia maximoviczii C,Iljinia regelii,Frankenia pulverulenta,Haloxylon persicum in China were analyzed using the CART(classification and regression tree) niche model,long term series climate change scenarios of A2 and B2,and 62 climate variables.The results showed that climate change in China would cause reduction in the current distribution of these plants,and the reduction were low for the Haloxylon persicum and Ajania fruticulosa,and the reduction were higher for the other plants,and climate change would cause an increasing in the new distribution or total distribution region of Frankenia pulverulenta from periods of 1991-2020 to periods of 2051-2080,then it would reduce.And climate change would not cause change significantly distribution of Cancrinia maximoviczii from periods of 1991-2020 to periods of 2081-2100,while it would cause reduction distribution of other plants decrease from periods of 1991-2020 to periods of 2081-2100,and they were higher in A2 scenario than that in B2 Scenario.Under climate change,the minimum or maximum or media of distribution of species would change different.Following climate change,some region of the south of current distribution regions of Haloxylon persicum,Frankenia pulverulenta,Iljinia regelii or Ajania fruticulosa,and some region of the north or east of current distribution regions of Stilpnolepis centiflora,and some region of the north or northwest of current distribution regions of Cancrinia maximoviczii,and some region of the north or northeast or northwest of current distribution regions of Reaumuria soongorica would all reduce,and the new distribution regions would expand towards some region of Qaidam Basin or Kunlun Mountain or Altun Mountain or Qilian Mountain or Pamir Plateau,while the distribution regions of Cancrinia maximoviczii C,Iljinia regelii or Frankenia pulverulenta from periods of 2051-2080 year to periods of 2081-2100 or the new distribution regions of Haloxylon Persicum from periods of 1991-2080 year to periods of 2081-2100 would expand towards some region of northeast of China,and they were higher in A2 scenario than that in B2 Scenario.Additionally,under climate change,changing in current distribution,new distribution or total distribution region of the plants did not consistently change with changing in annual mean air temperature or precipitation in China,and changing in current distribution,new distribution or total distribution region of some plants were poor related with changing in annual mean air temperature or precipitation in China.And the linear regression relationship between changing in the plants distribution and annual mean temperature and annual mean precipitation in China were poor.The results indicated that climate change in China will cause changing in spatial distribution pattern of these desert plants,and reduce in current distribution region of them,while increase in the new distribution region of the plants.Additionally,the results also indicated that there are high uncertain only using global or regional annual mean temperature to analyze the changing in the plants distribution following climate change.",
        "keywords": [
            "Desert",
            "Endangered Plant",
            "Spatial Distribution Pattern",
            "Climate Change"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Arid Land Geography",
        "year": 2011
    },
    "5rTb1FEQ": {
        "id": "5rTb1FEQ",
        "title": "The X protein of hepatitis B virus inhibits apoptosis in hepatoma cells through enhancing the methionine adenosyltransferase 2A gene expression and reducing S-adenosylmethionine production.",
        "abstract": "The X protein (HBx) of hepatitis B virus (HBV) is involved in the development of hepatocellular carcinoma (HCC), and methionine adenosyltransferase 2A (MAT2A) promotes the growth of liver cancer cells through altering S-adenosylmethionine homeostasis. Thus, we speculated that a link between HBx and MAT2A may contribute to HCC development. In this study, the effects of HBx on MAT2A expression and cell apoptosis were investigated, and the molecular mechanism by which HBx and MAT2A regulate tumorigenesis was evaluated. Results from immunohistochemistry analyses of 37 pairs of HBV-associated liver cancer tissues/corresponding peritumor tissues showed that HBx and MAT2A are highly expressed in most liver tumor tissues. Our in vitro results revealed that HBx activates MAT2A expression in a dose-dependent manner in hepatoma cells, and such regulation requires the cis-regulatory elements NF-κB and CREB on the MAT2A gene promoter. Electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP) further demonstrated that HBx facilitates the binding of NF-κB and CREB to MAT2A gene promoter. In addition, overexpression of HBx or MAT2A inhibits cell apoptosis, whereas knockdown of MAT2A expression stimulates apoptosis in hepatoma cells. Furthermore, we demonstrated that HBx reduces MAT1A expression and AdoMet production but enhances MAT2β expression. Thus, we proposed that HBx activates MAT2A expression through NF-κB and CREB signaling pathways to reduce AdoMet production, inhibit hepatoma cell apoptosis, and perhaps enhance HCC development. These findings should provide new insights into our understanding how the molecular mechanisms underline the effects of HBV infection on the production of MAT2A and the development of HCC.",
        "keywords": [
            "apoptosis",
            "immunohistochemistry",
            "gene expression profiling",
            "signal transduction",
            "nf kappa b",
            "plasmids"
        ],
        "authors": [
            {
                "name": "Quanyan Liu",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Jiwei Chen",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Li Liu",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Jun Zhang",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Dongfeng Wang",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Lu Ma",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yueming He",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhisu Liu",
                "org": "Zhongnan Hospital(Zhongnan Hospital),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "The Journal of biological chemistry",
        "year": 2011
    },
    "0b4P8RHG": {
        "id": "0b4P8RHG",
        "title": "On Strengthening the Spiritual and Cultural Construction of the Campus",
        "abstract": "The core competitiveness of the university, which can make the university achieve sustainable development in the competition, is the unique ability system through long-term formation and endoplasmic reticulum into the university integration. The spirit of a university embodied in the campus culture, and promoting the spirit of the university can upgrade the core competitiveness of the university. Although Nantong University has just been organized, Nantong Medical College, Nantong Institute of Technology and Nantong Teachers College had a long history and strong college culture. These colleges were from the same founder——Mr. Zhang Jian. From certain aspect, the spirit of Zhang Jian can be the spirit of Nantong University. During building the core competence of Nantong University, we should learn from Mr. Zhang Jian’s constantly enterprising spirit, patriotic spirit, the spirit of innovation and entrepreneurship. In order to enhance the core competitiveness of Nantong University, we should create a unique spirit and culture of Nantong University.",
        "keywords": [
            "core competence",
            "campus culture",
            "university spirit",
            "Nantong University"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": " School of Electrical Engineering, Nantong University, Nantong , Jiangsu, China"
            },
            {
                "name": "He Li-juan",
                "org": " Library of Nantong University, Nantong, , Jiangsu, China"
            }
        ],
        "venue": "Journal of Nantong University(Education Sciences Edition)",
        "year": 2010
    },
    "7evfK5h2": {
        "id": "7evfK5h2",
        "title": "Advances in human well-being research: A sustainability science perspective",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Huang Ganlin",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jiang Yaqiong",
                "org": "Beijing Normal University"
            },
            {
                "name": "Liu Zhifeng",
                "org": "Beijing Normal University"
            },
            {
                "name": "Nie Mei",
                "org": "Beijing Normal University"
            },
            {
                "name": "Liu Yang",
                "org": "Beijing Normal University"
            },
            {
                "name": "Li Jingwei",
                "org": "Beijing Normal University"
            },
            {
                "name": "Bao Yuyang",
                "org": "Beijing Normal University"
            },
            {
                "name": "Wang Yuhai",
                "org": "Beijing Normal University"
            },
            {
                "name": "Wu Jianguo",
                "org": "Sustainability, School of"
            }
        ],
        "venue": "Acta Ecologica Sinica",
        "year": 2016
    },
    "Sj6KCeGK": {
        "id": "Sj6KCeGK",
        "title": "The Emission Status and Composition Analysis of Municipal Solid Waste in China",
        "abstract": "The municipal solid waste treated in landfill can emit the methane to the atmosphere and increase the greenhouse gas concentration in the atmosphere,which has influences on the global climatic change.The statistic method was used to analyze the correlation of generating amount of municipal solid waste(MSW) with other driving factors,such as non-agriculture population,GDP and area of built district as well as the numbers of cities,etc.Based on the historical data analysis,survey in selected cities and calculation of MSW,the characters and trends of MSW were studied.The results show that the organic substance content and reusable material of MSW in south or big cities are higher than in north or medium and small cities,but the inorganic substance content is reverse.The organic composition has an increasing trend and the inorganic composition has a decreasing trend,but the trends change to steady gradually and the composition of municipal solid waste stabilizes in the same level in recent years.",
        "keywords": [
            "municipal solid waste",
            "emission",
            "composition",
            "generating amount",
            "transportation amount"
        ],
        "authors": [
            {
                "name": "DU Wu-peng",
                "org": ""
            },
            {
                "name": "GAO Qing-xian",
                "org": "Chinese Research Academy of Environment Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG En-chen",
                "org": "Shenyang Environ-Engineering Design and Research Institute,Shenyang ,China"
            },
            {
                "name": "MIAO Qi-long",
                "org": "Nanjing University of Information Sciences and Technology,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environment Sciences,Beijing ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2006
    },
    "sc9lfrDl": {
        "id": "sc9lfrDl",
        "title": "Characterization of Influenza A and B Viruses Circulating in Southern China During the 2017-2018 Season.",
        "abstract": "The trivalent seasonal influenza vaccine was the only approved and available vaccine during the 2016-2018 influenza seasons. It did not include the B/Yamagata strain. In this study, we report an acute respiratory disease outbreak associated with influenza B/Yamagata infections in Guangzhou, Southern China (January through March, 2018). Among the 9914 patients, 2241 (22.6%) were positive for the influenza B virus, with only 312 (3.1%) positive for the influenza A virus. The influenza B/Yamagata lineage dominated during this period in Southern China. The highest incidence of influenza A virus infection occurred in the children aged 5-14 years. In contrast, populations across all age groups were susceptible to the influenza B virus. Phylogenetic, mutations, and 3D structure analyses of hemagglutinin (HA) genes were performed to assess the vaccine-virus relatedness. The recommended A/H1N1 vaccine strain (A/Michigan/45/2015) during both 2017-2018 and 2018-2019 was antigen-specific for these circulating isolates (clade 6B.1) in Spring 2018. An outbreak of influenza B/Yamagata (clade 3) infections in 2018 occurred during the absence of the corresponding vaccine during 2016-2018. The recommended influenza B/Yamagata vaccine strain (B/Phuket/3073/2013) for the following season (2018-2019) was antigen-specific. Although there were only a few influenza B/Victoria infections in Spring 2018, five amino acid mutations were identified in the HA antigenic sites of the 19 B/Victoria isolates (clade 1A), when compared with the 2016-2018 B/Victoria vaccine strain. The number was larger than expected and suggested that the influenza B HA gene may be more variable than previously thought. One of the mutations (K180N) was noted to likely alter the epitope and to potentially affect the viral antigenicity. Seven mutations were also identified in the HA antigenic sites of 2018-2020 B/Victoria vaccine strain, of which some or all may reduce immunogenicity and the protective efficacy of the vaccine, perhaps leading to more outbreaks in subsequent seasons. The combined epidemiological, phylogenetic, mutations, and 3D structural analyses of the HA genes of influenza strains reported here contribute to the understanding and evaluation of how HA mutations affect vaccine efficacy, as well as to providing important data for screening and selecting more specific, appropriate, and effective influenza vaccine candidate strains.",
        "keywords": [
            "3D structure analysis",
            "Victoria lineage",
            "Yamagata lineage",
            "antigenic sites",
            "hemagglutinin",
            "influenza B virus",
            "mutation analysis",
            "phylogenetic analysis"
        ],
        "authors": [
            {
                "name": "Yuqian Yan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Junxian Ou",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Shan Zhao",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Kui Ma",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Wendong Lan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Wenyi Guan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Xiaowei Wu",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Jing Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Bao Zhang",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Wei Zhao",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Chengsong Wan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Weifeng Shi",
                "org": "Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases in Universities of Shandong, Shandong First Medical University & Shandong Academy of Medical Sciences, Taian, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Donald Seto",
                "org": "Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VA, United States."
            },
            {
                "name": "Zhiwu Yu",
                "org": "Division of Laboratory Science, The Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, China."
            },
            {
                "name": "Qiwei Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "Frontiers in microbiology",
        "year": 2020
    },
    "yjLh2KeB": {
        "id": "yjLh2KeB",
        "title": "Dynamic genetic effects on threonine content in rapeseed (brassica napus l.) meal at different developmental stages",
        "abstract": "Dynamic genetic effects on threonine content (TC) of rapeseed (Brassica napus L.) meal were analysed at 5 developmental times/stages using the genetic models for diploid plant seeds. Results indicated that the expression of diploid embryo, cytoplasmic and diploid maternal plant genes were all important for the performance of TC at various developmental times/stages of rapeseed, especially at the early and middle developmental stages. Among different genetic systems, TC was mainly controlled by the cumulative or net maternal main effects and the genotype × environment (GE) interaction effects, followed by the embryo main effects and GE interaction effects. The expression of genes was more easily influenced by the environmental factors at the first three developmental stages. The total narrow-sense heritabilities for TC on 15, 22, 29, 36 and 43 days post anthesis were 46.50, 62.60, 57.10, 84.70 and 59.50%, respectively, of which the interaction heritabilities were more important at the first three developmental stages of rapeseed. The improvement in TC of rapeseed meal could be expected by selection based on the higher narrow-sense heritabilities near maturity. The predicted genetic effects of parents showed that TC of progeny could be improved by using the parent Gaoyou 605.",
        "keywords": [
            "developmental genetics",
            "genetic variances and conditional genetic variances",
            "heritability",
            "rapeseed meal",
            "threonine content",
            "gene expression",
            "developmental stages",
            "chemical composition",
            "genetic variance",
            "genes",
            "genotype environment interaction",
            "diploidy",
            "maternal effects"
        ],
        "authors": [
            {
                "name": "Guolin Chen",
                "org": "Zhejiang Agriculture and Forestry University(Zhejiang Agriculture and Forestry University,School of Engineering, Zhejiang Agriculture and Forestry University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Czech Journal of Genetics and Plant Breeding",
        "year": 2011
    },
    "0JJZITOV": {
        "id": "0JJZITOV",
        "title": "Impacts of urbanization on summer climate in China: An assessment with coupled land‐atmospheric modeling",
        "abstract": "China has experienced unprecedented urbanization since the 1980s, resulting in substantial climatic effects from local cities to broad regions. Using the Weather Research and Forecasting model dynamically coupled to an urban canopy model, we quantified the summertime climate effects of urban expansion in Chinau0027s most rapidly urbanizing regions: Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (YRD), and Pearl River Delta (PRD). High-resolution landscape data of each urban agglomeration for 1988, 2000, and 2010 were used for simulations. Our results indicated summertime urban warming of 0.85 °C for BTH, 0.78 °C for YRD, and 0.57 °C for PRD, which was substantially greater than previous estimates. Peak summer warming for BTH, YRD, and PRD was 1.5 °C, 1 °C, and 0.8 °C, respectively. In contrast, the loss of moisture was greatest in PRD, with maximum reduction in 2-m water vapor mixing ratio close to 1 g/kg, followed by YRD and BTH with local peak humidity deficits reaching 0.8 g/kg and 0.6 g/kg, respectively. Our results were in better agreement with observations than prior studies because of the usage of high-resolution landscape data and the inclusion of key land-atmospheric interactions. Our study also demonstrated that the warming impacts of polycentric urban forms were less intense but more extensive in space, whereas large concentrated urban aggregations produced much stronger but localized warming effects. These findings provide critical knowledge that improves our understanding of urban-atmospheric interactions, with important implications for urban landscape management and planning to alleviate the negative impacts of urban heat islands.",
        "keywords": "",
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Center for Human‐Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal University Beijing China"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human‐Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal University Beijing China"
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning Arizona State University Tempe Arizona USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human‐Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal University Beijing China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human‐Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal University Beijing China"
            }
        ],
        "venue": "Journal of Geophysical Research",
        "year": 2016
    },
    "ymEQY27o": {
        "id": "ymEQY27o",
        "title": "Ethanol extract from ampelopsis sinica root exerts anti-hepatitis B virus activity via inhibition of p53 pathway in vitro",
        "abstract": "Ampelopsis sinica root is widely used in Chinese folk medicine for treating liver disorders caused by the hepatitis B virus (HBV). The present study was performed in order to investigate the anti-HBV activity and mechanisms of the ethanol extract from A. sinica root (EASR) in vitro. The antiviral activity of EASR was examined by detecting the levels of HBsAg, HBeAg and extracellular HBV DNAs in stable HBV-producing human hepatoblastoma HepG2 2.2.15 cells. We found that EASR effectively suppressed the secretion of HBsAg and HBeAg from HepG2 2.2.15 cells in a dose-dependent manner, and it also suppressed the amount of extracellular HBV DNA. After EASR treatment, the percentage of apoptotic cells was found to be significantly higher than that of control by flow cytometric analysis. A luciferase reporter gene assay was used to determine the effects of EASR on the activities of HBV promoters and intracellular signaling pathways. The results showed that EASR selectively inhibited the activities of HBV promoters (Cp, S1p and Fp) and the p53 signaling pathway in HepG2 cells significantly. These data indicate that EASR exerts anti-HBV effects via inhibition of HBV promoters and the p53-associated signaling pathway, which helps to elucidate the mechanism underlying the potential therapeutic value of EASR. © 2011 Ran Pang et al.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "ShuLing Zhang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ran Pang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Junyan Tao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Keli Chen",
                "org": "Hubei College of Traditional Chinese Medicine(Hubei College of Traditional Chinese Medicine),Wuhan,China"
            },
            {
                "name": "Lei Zhao",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Xin Yue",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yuefeng Wang",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Pian Ye",
                "org": "Huazhong University of Science and Technology(Huazhong University of Science and Technology,Huazhong Univ. of Sci. and Technol.),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Evidence-based Complementary and Alternative Medicine",
        "year": 2011
    },
    "FLoRADTP": {
        "id": "FLoRADTP",
        "title": "Antioxidant activity of polysaccharide extracted from Ganoderma lucidum using response surface methodology.",
        "abstract": "Superfine grinding technology was applied for polysaccharide extraction from the fruiting bodies of Ganoderma lucidum, and response surface methodology (RSM) was used to optimize the effects of processing parameters on polysaccharide extraction yield. Results showed that the maximum yield of G. lucidum polysaccharides (GLP) was obtained at an optimum condition: extraction time 137 min, extraction temperature 66 ̊C, the ratio of water to material 35 mL/g, and the GLP extracting yield reached 2.44% under this condition. GLP were precipitated into three crude polysaccharides, viz. GLP40, GLP60 and GLP80. The basic characterization of polysaccharides was determined by using HPLC and FT-IR methods. GLP, GLP80, GLP60, and GLP40 were composed of Man, Rib, Glc, Gal and Fuc with the molar ratios of 1.27:0.36:22.89:1.61:0.33, 1.40:0.31:23.02:3.46:0.91, 0.96:0.34:25.76:2.47:0.46, and 2.81:1.42:23.83:1.61:0.33, respectively. The result of FT-IR suggested that the monosaccharide residue of the four polysaccharides was β-pyranoid ring. Moreover, the antioxidant activities of these four polysaccharides were evaluated. The results showed that GLP80 had the best reducing power, DPPH radical scavenging ability and oxygen radical scavenging ability followed by GLP, GLP60 and GLP40. Our results demonstrated that RSM might be a valuable technique for optimizing the efficient extraction of GLP, and G. lucidum could be considered as sources of natural antioxidants and preservatives of food industry. Moreover, polysaccharides, especially GLP80, extracted from the fruiting bodies of G. lucidum, exhibited promising antioxidant activities.",
        "keywords": [
            "antioxidant activity",
            "ganoderma lucidum",
            "polysaccharide"
        ],
        "authors": [
            {
                "name": "Yongjun Kan",
                "org": "Pharmacy College, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, PR China."
            },
            {
                "name": "Tiqiang Chen",
                "org": "Institute of Edible Fungi, Fujian Academy of Agricultural Sciences, Fuzhou 350013, PR China."
            },
            {
                "name": "Yanbin Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, PR China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, PR China."
            },
            {
                "name": "Jinzhong Wu",
                "org": "Pharmacy College, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, PR China; Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, PR China."
            }
        ],
        "venue": "International journal of biological macromolecules",
        "year": 2015
    },
    "7X0fWoAt": {
        "id": "7X0fWoAt",
        "title": "Some Tentative Suggestion on Innovation Education in Economic Mathematics",
        "abstract": "Based on the analysis of the problems existing in the course of economic mathematics,the paper puts forward some tentative suggestion on the curricular content arrangement,improving on teaching method and cultivation of the application ability of students in economic mathematics.",
        "keywords": [
            "course reform",
            "innovation education",
            "economic mathematics"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Department of Mathematics,Hunan College of Finance and Economics,Changsha ,China"
            }
        ],
        "venue": "College Mathematics",
        "year": 2007
    },
    "ZDyxRmE4": {
        "id": "ZDyxRmE4",
        "title": "Detecting relationships between amylose content and amino acid contents of indica rice with conditional approach",
        "abstract": "The relationship between the genetic effects of endosperm, cytoplasm and maternal plant on amylose content (AC) and amino acid contents of indica rice was studied using unconditional and conditional analysis methods. The results indicated that the protein content (PC) and brown rice weight (WBR) could significantly affect the relationships between AC and amino acid contents of rice. The phenotypic and genotypic covariances between AC and amino acid contents were most significantly negative under the interference of PC or WBR, but most of the relationships for the paired traits were not significant after excluding the influence of PC or WBR on AC. For the conditional genetic relationship analysis of different genetic systems including endosperm, cytoplasm and maternal plant, visible changes were found in many genetic correlation components between AC and amino acid content after eliminating the influences of PC, especially, for the endosperm or maternal additive effects, endosperm additive or dominance interaction effects and maternal additive interaction effects. The relationships of the paired traits conditioned on WBR were mainly controlled by the endosperm dominance or additive interaction effects. © 2010 Indian Academy of Sciences.",
        "keywords": [
            "amino acid contents",
            "amylose content",
            "indica rice (oryza sativa l.)",
            "protein content",
            "unconditional and conditional covariance analysis",
            "weight of brown rice",
            "covariance analysis",
            "amino acid",
            "genetic correlation",
            "interaction effect",
            "genetics"
        ],
        "authors": [
            {
                "name": "Chun Hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Qiong Qiong Zhu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ke Ming Wang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Guo Ke Ge",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian Guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhen Ghao Xu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of Genetics",
        "year": 2010
    },
    "0Cbypda2": {
        "id": "0Cbypda2",
        "title": "OA03.01 A Non-Randomized, Open-Label, Prospective, Multicenter Study of Apatinib as Second-Line and Later-Line Therapy in Patients with ES-SCLC",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "D. Hua",
                "org": ""
            },
            {
                "name": "Q. Liu",
                "org": ""
            },
            {
                "name": "J. Xu",
                "org": ""
            },
            {
                "name": "Y. Xu",
                "org": ""
            },
            {
                "name": "M. Chen",
                "org": ""
            },
            {
                "name": "L. Deng",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "T. Zhou",
                "org": ""
            },
            {
                "name": "L. Zhang",
                "org": ""
            },
            {
                "name": "J. Tan",
                "org": ""
            },
            {
                "name": "X. Pu",
                "org": ""
            },
            {
                "name": "Y. Shang",
                "org": ""
            },
            {
                "name": "J. Hua",
                "org": ""
            },
            {
                "name": "Y. Li",
                "org": ""
            },
            {
                "name": "W. Cai",
                "org": ""
            },
            {
                "name": "Y. Gu",
                "org": ""
            },
            {
                "name": "X. Peng",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2019
    },
    "Gu0GTsAN": {
        "id": "Gu0GTsAN",
        "title": "Optimization of producing conditions of β-mannan mannohydrolase of Irpex lacteus",
        "abstract": "The producing conditions of β-mannan mannohydrolase of Irpex lacteus were optimized,including concentration of konjac power,choice of nitrogen resource,recombinant proportion of nitrogen resource,concentration of nitrogen resource and innoculation volume,at last the producing-enzyme kinetic was analyzed.The optimization conditions were obtained as follows:konjac power concentration was 2%,and peptone and ammonium sulfate were choose as nitrogen resource,and the recombinant proportion was 1:2,and nitrogen resource concentration was 0.4%,innoculation volume was 10%.Under this optimization conditions,the β-mannan mannohydrolase activity reached to 48.1IU/mL after fermentation for 4d,which was 2.3 times than the activity of control sample.",
        "keywords": [
            "konjac",
            "β-mannan mannohydrolase",
            "fermentation",
            "Irpex lacteus"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "WU Feng",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "LIU Feng",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Science and Technology of Food Industry",
        "year": 2009
    },
    "PiSqcK4o": {
        "id": "PiSqcK4o",
        "title": "Calculation on elementary plate panel bulking for hull hold section of a 20 000t bulk carrier based on CSR",
        "abstract": "Based on stress analysis of CSR for a 20 000 t bulk carrier,the elementary plate panel buckling of mid-hold sections has been calculated by elementary plate panel bulking program.The program is developed on MSC/PATRAN pre-treatment program platform of MSC/NASTRAN,and the result has been evaluated.",
        "keywords": [
            "stress analysis",
            "buckling",
            "CSR",
            "bulk carrier",
            "elementary plate panel"
        ],
        "authors": [
            {
                "name": "Zhang Liaoqi",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            },
            {
                "name": "Zhang Zhigang",
                "org": ""
            }
        ],
        "venue": "Ship & Boat",
        "year": 2008
    },
    "8qS3stqW": {
        "id": "8qS3stqW",
        "title": "HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1.",
        "abstract": "Upon recognition of viral components by pattern recognition receptors, such as the toll-like receptors (TLRs) and retinoic acid-inducible gene I (RIG-I)-like helicases, cells are activated to produce type I interferon (IFN) and proinflammatory cytokines. These pathways are tightly regulated by the host to prevent an inappropriate cellular response, but viruses can modulate these pathways to proliferate and spread. In this study, we revealed a novel mechanism in which hepatitis C virus (HCV) evades the immune surveillance system to proliferate by activating microRNA-21 (miR-21). We demonstrated that HCV infection upregulates miR-21, which in turn suppresses HCV-triggered type I IFN production, thus promoting HCV replication. Furthermore, we demonstrated that miR-21 targets two important factors in the TLR signaling pathway, myeloid differentiation factor 88 (MyD88) and interleukin-1 receptor-associated kinase 1 (IRAK1), which are involved in HCV-induced type I IFN production. HCV-mediated activation of miR-21 expression requires viral proteins and several signaling components. Moreover, we identified a transcription factor, activating protein-1 (AP-1), which is partly responsible for miR-21 induction in response to HCV infection through PKCε/JNK/c-Jun and PKCα/ERK/c-Fos cascades. Taken together, our results indicate that miR-21 is upregulated during HCV infection and negatively regulates IFN-α signaling through MyD88 and IRAK1 and may be a potential therapeutic target for antiviral intervention.",
        "keywords": [
            "protein kinase c",
            "micrornas",
            "hek293 cells",
            "phosphorylation",
            "rna interference",
            "up regulation"
        ],
        "authors": [
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Junbo Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Hui Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jingjing Shi",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Shi Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2013
    },
    "EIotYNjT": {
        "id": "EIotYNjT",
        "title": "Understanding Land System Change Through Scenario-Based Simulations: A Case Study from the Drylands in Northern China",
        "abstract": "The drylands in northern China are expected to face dramatic land system change in the context of socioeconomic development and environmental conservation. Recent studies have addressed changes of land cover with socioeconomic development in the drylands in northern China. However, the changes in land use intensity and the potential role of environmental conservation measures have yet to be adequately examined. Given the importance of land management intensity to the ecological conditions and regional sustainability, our study projected land system change in Hohhot city in the drylands in northern China from 2013 to 2030. Here, land systems are defined as combinations of land cover and land use intensity. Using the CLUMondo model, we simulated land system change in Hohhot under three scenarios: a scenario following historical trends, a scenario with strong socioeconomic and land use planning, and a scenario focused on achieving environmental conservation targets. Our results showed that Hohhot is likely to experience agricultural intensification and urban growth under all three scenarios. The agricultural intensity and the urban growth rate were much higher under the historical trend scenario compared to those with more planning interventions. The dynamics of grasslands depend strongly on projections of livestock and other claims on land resources. In the historical trend scenario, intensively grazed grasslands increase whereas a large amount of the current area of grasslands with livestock converts to forest under the scenario with strong planning. Strong conversion from grasslands with livestock and extensive cropland to semi-natural grasslands was estimated under the conservation scenario. The findings provide an input into discussions about environmental management, planning and sustainable land system design for Hohhot.",
        "keywords": [
            "Conservation",
            "Historical land use change",
            "Hohhot",
            "Land use intensity",
            "Land use model",
            "Land use planning"
        ],
        "authors": [
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,People’s Republic of ChinaDepartment of Earth Sciences, Environmental Geography group,VU University Amsterdam,Amsterdam,The Netherlands"
            },
            {
                "name": "Peter H. Verburg",
                "org": "Department of Earth Sciences, Environmental Geography group,VU University Amsterdam,Amsterdam,The Netherlands"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,People’s Republic of ChinaSchool of Life Sciences and School of Sustainability, Arizona State University,Tempe,USA"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,People’s Republic of China"
            }
        ],
        "venue": "Environmental Management",
        "year": 2017
    },
    "asvsWtX1": {
        "id": "asvsWtX1",
        "title": "Genetic and genotype x environment interaction effects analysis for erucic acid content in rapeseed (Brassica napus L.)",
        "abstract": "Genetic main effects and genotype × environment (GE) interaction effects for erucic acid content (EAC) in rapeseed(Brassica napus L.) were analyzed for two year data by using the genetic models and corresponding statistical approaches for quantitative traits of diploid plant seeds. Eight parents were included in adiallel mating design in two environments. It was found that the embryo, cytoplasmic and maternal main effects and their GE interaction effects could simultaneously affect the performance of EAC, especially for the cytoplasmic and maternal effects. Since the amount of genetic main effects from the expression of genes in different genetic systems accounted for about 64.1%of the total genetic effects, EAC of rapeseed was mainly controlled by genetic main effects. The total narrow-sense heritability for EAC was 83.6% with the general heritability being 51.9% and the interaction heritability being 31.7%. It was suggested by the predicted genetic effects, that Tower and Youcai 601 were better than other parents for reducing EAC in rapeseed quality breeding.",
        "keywords": [
            "erucic acid",
            " genetic effect",
            " heritability",
            " quality",
            " rapeseed (Brassica napus L."
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "HaiZhen Zhang",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Changtao Li",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Yuling Ren",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Euphytica",
        "year": 2003
    },
    "ItUv22cF": {
        "id": "ItUv22cF",
        "title": "The biophysical effects of the vegetation restoration program on regional climate metrics in the Loess Plateau, China",
        "abstract": "The Grain to Green (GTG) program launched in 1999 by the Chinese government is one of the largest ecological restoration programs ever implemented in the world. Although the GTG program has been demonstrated to affect ecosystem services in the revegetated areas, its impacts on regional climate are seldom reported and poorly understood. Therefore, our study examined the impacts of revegetation owing to the GTG program on summer climate in the Loess Plateau, by incorporating near real-time remotely sensed land use/land cover data and vegetation characteristics of 2001 and 2010 into a coupled land-atmosphere model. From 2001 to 2010, a considerable portion of croplands was converted to forests and grasslands, with vegetation fraction and LAI increasing while surface albedo decreasing throughout the Loess Plateau. Compared with those from 2001, simulation results from 2010 indicated lowered 2-m air temperature in summer, with the magnitude of reduction in nighttime minimum (as high as 0.8-1.0 degrees C) greater than that in daytime maximum (generally restricted to 0.4 degrees C). The concurrent decrease in summertime 2-m specific humidity further led to widespread reduction of near-surface heat content (i.e., moist enthalpy). Summer precipitation decreased in northern Shanxi province and western Loess Plateau (up to 1.0-1.4 mm/day) while increasing in southeastern Loess Plateau (between 1.0-2.0 mm/day). Our findings underscore that vegetation restoration has exerted strong influences on regional climate, and provide useful information for the sustainable implementation of the GTG program.",
        "keywords": [
            "The Grain to Green program",
            "Afforestation",
            "Vegetation characteristics",
            "Land use/land cover",
            "Land-atmosphere interaction",
            "WRF"
        ],
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, College of Natural Resources, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, College of Natural Resources, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, College of Natural Resources, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, College of Natural Resources, Faculty of Geographical Science, Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Wei Wang",
                "org": "Mesoscale & Microscale Meteorology Laboratory, National Center for Atmospheric Research (NCAR), Boulder, CO, 80301, United States"
            }
        ],
        "venue": "AGRICULTURAL AND FOREST METEOROLOGY",
        "year": 2019
    },
    "wqVqgaCF": {
        "id": "wqVqgaCF",
        "title": "The Effects of Change in Temperature and Soil Moisture on the Seed Germination of Three Typical Desert Plants",
        "abstract": "The response of plant seed germination to changes in temperature and soil moisture is crucial to the impact of climate change on the desert ecosystem. In order to analyze the response trend of seed germination of desert plants to changes in temperature and soil moisture,three typical desert plants Mongolian Calligonum(Calligonum mongolica),Nitraria Sphaerocarpa(Nitraria sphaerocarpa) and Ma Huang(Ephedra przewalskii) were chosen,and their seed germinations in different air temperature((16 ℃) /(22 ℃) and(21 ℃) /(27 ℃)), soil moistures(3%, 5% and 15%),soaking(12 h) and without soaking in artificial climatic chambers were investigated.The results showed that,for Mongolian Calligonum and Nitraria Sphaerocarpa,the seed germination percentages increased with increasing soil moisture;and,with increasing air temperature,the seed germination percentage increased more for soaked seeds than for unsoaked seeds.For Ma Huang,with increasing air temperature,the seed germination percentage increased more for unsoaked seeds than for soaked seeds;and,the increase of seed germination percentage with increasing air temperature for soaked seeds under 3% soil moisture was higher than that under 5% or 15% soil moisture((P<)0.05).The index of seed germination for Mongolian Calligonum,Nitraria Sphaerocarpa and Ma Huang increased with increasing soil moisture or air temperature.For Mongolian Calligonum and Nitraria Sphaerocarpa,the increase of seed germination index with increasing air temperature for unsoaked seeds was higher than for soaked seeds.For Ma Huang,the increased of seed germination index with increasing air temperature for soaked seeds was higher than for unsoaked seeds.The seed germination rates for the three plants increased quickly during the early and middle incubation periods.The seed germination of these desert plants was influenced by the air temperature and soil moisture together,and the responses of different plant seed germinations to changes in these factors were different.",
        "keywords": [
            "desert ecosystem",
            "seed germination",
            "climate change",
            "air temperature",
            "temperature",
            "climatic change"
        ],
        "authors": [
            {
                "name": "wu jianguo",
                "org": ""
            },
            {
                "name": "chang wei",
                "org": ""
            },
            {
                "name": "lujiajia",
                "org": ""
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2009
    },
    "VfNcAptp": {
        "id": "VfNcAptp",
        "title": "Grassland ecosystem services: a systematic review of research advances and future directions",
        "abstract": "Grasslands provide a variety of ecosystem services (ESs) for humans. While much ES research has focused on forests and wetlands, synthesizing the currently somewhat sporadic studies of grassland ecosystem services (GESs) is much needed. We aimed to review the scope, major methods, and key findings of GESs, and identify knowledge gaps and future directions. We conducted a systematic review of articles published during 1970–2018 (including 380 peer-reviewed articles from Web of Science and 32 book chapters from Google Scholar). The number of GES studies has accelerated in recent decades, with China (31%) and the United States (18%) together accounting for almost half of them. A total of 33 GESs were mentioned in the searched articles, of which carbon sequestration, forage production, and water erosion control had the highest frequencies. Methods for evaluating GESs include field survey, field experiments, and statistical and process-based modeling. Grasslands are the primary source of meat and dairy products, account for about one-third of the total carbon of all terrestrial ecosystems, and provide numerous other ESs, such as night cooling, soil erosion control, and flood mitigation. This review presents the state-of-the-science of GESs, and identifies several future research directions. To move forward, we propose a framework with a 3-M methodology: (1) “Multi-scales”—understanding GESs from various spatiotemporal scales; (2) “Multi-methods”—evaluating GESs with multiple statistical and modeling techniques using multiple data sources; and (3) “Multi-perspectives”—assessing GESs from ecological, social, and economic perspectives for sustainability.",
        "keywords": [
            "Grassland ecosystem services",
            " Systematic review",
            " Provisioning services",
            " Regulating services",
            " Cultural services",
            " Grassland sustainability"
        ],
        "authors": [
            {
                "name": "Yuanyuan Zhao",
                "org": "Yanchi Research Station, School of Soil and Water Conservation, Beijing Forestry University, Beijing, China"
            },
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human–Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human–Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, China"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2020
    },
    "1TkNyCBA": {
        "id": "1TkNyCBA",
        "title": "Habitat fragmentation and biodiversity conservation: key findings and future challenges",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "maxwell c wilson",
                "org": "arizona state university"
            },
            {
                "name": "xiaoyong chen",
                "org": "east china normal university"
            },
            {
                "name": "richard t corlett",
                "org": "chinese academy of sciences"
            },
            {
                "name": "raphael k didham",
                "org": "university of western australia"
            },
            {
                "name": "ping ding",
                "org": "zhejiang university"
            },
            {
                "name": "robert d holt",
                "org": "university of florida"
            },
            {
                "name": "marcel holyoak",
                "org": "university of california"
            },
            {
                "name": "guang hu",
                "org": "zhejiang university of science and technology"
            },
            {
                "name": "alice c hughes",
                "org": "chinese academy of sciences"
            },
            {
                "name": "lin jiang",
                "org": "georgia institute of technology"
            },
            {
                "name": "william f laurance",
                "org": "james cook university"
            },
            {
                "name": "jiajia liu",
                "org": "zhejiang university"
            },
            {
                "name": "stuart l pimm",
                "org": "duke university"
            },
            {
                "name": "scott k robinson",
                "org": "university of florida"
            },
            {
                "name": "sabrina e russo",
                "org": "university of nebraska lincoln"
            },
            {
                "name": "xingfeng si",
                "org": "zhejiang university"
            },
            {
                "name": "david s wilcove",
                "org": "princeton university"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "mingjian yu",
                "org": "zhejiang university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "y28MDmsG": {
        "id": "y28MDmsG",
        "title": "Study on the brewing technology of orange wine",
        "abstract": "The orange wine was produced using the Sichuan orange as raw material. The optimal production conditions were obtained through single factor experiments and orthogonal experiments as followed: main fermentation temperature 22℃,yeast inoculum 7%,added amount of SO2 70 mg/L,initial pH 3.7,initial sugar level 18°Bx. Under these conditions,high quality orange wine was produced.",
        "keywords": [
            "technology",
            "orange wine",
            "brewing"
        ],
        "authors": [
            {
                "name": "WANG Lan",
                "org": "Yancheng Institute of Textile Technology,Yancheng ,China; School of Food Science and Technology,Jiangnan University,Wuxi ,China"
            },
            {
                "name": "XIA Bingbing",
                "org": "Department of Biotechnology Engineering,Sichuan University of Science & Engineering,Zigong ,China."
            },
            {
                "name": "ZHANG Xuefeng",
                "org": "Department of Biotechnology Engineering,Sichuan University of Science & Engineering,Zigong ,China."
            },
            {
                "name": "WU Jianguo",
                "org": "Department of Biotechnology Engineering,Sichuan University of Science & Engineering,Zigong ,China."
            }
        ],
        "venue": "China Brewing",
        "year": 2008
    },
    "5hI8uJM8": {
        "id": "5hI8uJM8",
        "title": "Behind the rapid expansion of urban impervious surfaces in China: Major influencing factors revealed by a hierarchical multiscale analysis",
        "abstract": "Urban impervious surfaces (UIS) are well known to have negative impacts on the environment. Studies that consider multiple UIS-influencing factors at multiple administrative levels and spatial scales are still lacking. The main goal of this study was to determine the major socioeconomic factors that shaped the spatiotemporal patterns of UIS in China from the county to provincial levels over the most recent decades. Specifically, remote sensing and statistical data from 1992 to 2009 were used to examine the relationship of UIS to a suite of socioeconomic factors across hierarchical administrative levels from small (county), medium (prefectural) to large (provincial) levels. Our results show that the key influencing factors of UIS varied substantially across hierarchical administrative levels: economic factors dominated the provincial level, demographic factors were most significant at the county level, and a mixed group of economic, demographic and traffic factors were important at the prefectural level. This suggests that, for determining major influencing factors for UIS, a hierarchical or multiscale approach is preferred to any single-scale analysis. Our findings from such a hierarchical perspective provide useful information for formulating mitigation strategies for excessive UIS expansions and for designing more sustainable cities. It is recommended that policies to control rampant expansion of UIS in China need to combine macro-scale economic regulations with micro-scale demographic planning measures.",
        "keywords": "",
        "authors": [
            {
                "name": "Qun Ma",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            }
        ],
        "venue": "Land Use Policy",
        "year": 2016
    },
    "TIhXkJSD": {
        "id": "TIhXkJSD",
        "title": "Testing biodiversity-ecosystem functioning relationship in the world’s largest grassland: overview of the IMGRE project",
        "abstract": "The relationship between biodiversity and ecosystem functioning (BEF) is a central topic in ecology on local, regional, and global scales. A powerful approach to BEF studies is large-scale field manipulative experimentation.",
        "keywords": [
            "Biodiversity and ecosystem functioning relationship",
            " BEF removal experiments",
            " Ecological stoichiometry",
            " Plant functional types",
            " Inner Mongolian grasslands"
        ],
        "authors": [
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "shahid naeem",
                "org": "columbia university"
            },
            {
                "name": "james j elser",
                "org": "arizona state university"
            },
            {
                "name": "yongfei bai",
                "org": "chinese academy of sciences"
            },
            {
                "name": "jianhui huang",
                "org": "chinese academy of sciences"
            },
            {
                "name": "le kang",
                "org": "chinese academy of sciences"
            },
            {
                "name": "qingmin pan",
                "org": "chinese academy of sciences"
            },
            {
                "name": "qibing wang",
                "org": "chinese academy of sciences"
            },
            {
                "name": "shuguang hao",
                "org": "chinese academy of sciences"
            },
            {
                "name": "xingguo han",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "vzH6rfnq": {
        "id": "vzH6rfnq",
        "title": "Engineered external guide sequences are highly effective in inhibiting gene expression and replication of hepatitis B virus in cultured cells.",
        "abstract": "External guide sequences (EGSs) are RNA molecules that consist of a sequence complementary to a target mRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, for specific degradation of the target mRNA. We have previously used an in vitro selection procedure to generate EGS variants that efficiently induce human RNase P to cleave a target mRNA in vitro. In this study, we constructed EGSs from a variant to target the overlapping region of the S mRNA, pre-S/L mRNA, and pregenomic RNA (pgRNA) of hepatitis B virus (HBV), which are essential for viral replication and infection. The EGS variant was about 50-fold more efficient in inducing human RNase P to cleave the mRNA in vitro than the EGS derived from a natural tRNA. Following Salmonella-mediated gene delivery, the EGSs were expressed in cultured HBV-carrying cells. A reduction of about 97% and 75% in the level of HBV RNAs and proteins and an inhibition of about 6,000- and 130-fold in the levels of capsid-associated HBV DNA were observed in cells treated with Salmonella vectors carrying the expression cassette for the variant and the tRNA-derived EGS, respectively. Our study provides direct evidence that the EGS variant is more effective in blocking HBV gene expression and DNA replication than the tRNA-derived EGS. Furthermore, these results demonstrate the feasibility of developing Salmonella-mediated gene delivery of highly active EGS RNA variants as a novel approach for gene-targeting applications such as anti-HBV therapy.",
        "keywords": [
            "chemistry",
            "virus replication",
            "genetic engineering",
            "biology",
            "engineering",
            "medicine",
            "gene targeting",
            "physics"
        ],
        "authors": [
            {
                "name": "Zhigang Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Gia-Phong Vu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Hao Gong",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Chuan Xia",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yuan-Chuan Chen",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Fenyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Sangwei Lu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "f4niMW3J": {
        "id": "f4niMW3J",
        "title": "Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication.",
        "abstract": "Hepatitis B virus (HBV) chronically infects approximately 350 million people worldwide, and 600,000 deaths are caused by HBV-related hepatic failure, liver cirrhosis, and hepatocellular carcinoma annually. It is important to reveal the mechanism underlying the regulation of HBV replication. This study demonstrated that the osteopetrosis-associated transmembrane protein 1 (Ostm1) plays an inhibitory role in HBV replication. Ostm1 represses the levels of HBeAg and HBsAg proteins, HBV 3.5-kb and 2.4/2.1-kb RNAs, and core-associated DNA in HepG2, Huh7, and NTCP-HepG2 cells. Notably, Ostm1 has no direct effect on the activity of HBV promoters or the transcription of HBV RNAs, instead, Ostm1 binds to HBV RNA to facilitate the RNA decay. Detailed studies further demonstrated that Ostm1 binds to and recruits RNA exosome complex to promote the degradation of HBV RNAs, and knock-down of RNA exosome component exonuclease 3 (Exosc3) leads to the elimination of Ostm1-mediated repression of HBV replication. Mutant analyses revealed that N-terminal domain, the transmembrane domain, and C-terminal domain are responsible for the repression of HBV replication and C-terminal domain is required for the interaction with RNA exosome complex. Moreover, Ostm1 production is not regulated by interferon-α (IFN-α) or IFN-γ, and the expression of INF signaling components is not affected by Ostm1, suggesting that Ostm1 anti-HBV activity is independent on IFN signaling pathway. In conclusion, this study revealed a distinct mechanism underlying the repression of HBV replication, in which Ostm1 binds to HBV RNA and recruits RNA exosome to degrade the viral RNA, thereby restricting HBV replication. Hepatitis B virus (HBV) is a human pathogen infecting liver to cause a variety of diseases ranging from acute hepatitis to advanced liver diseases, fulminate hepatitis, liver cirrhosis, and hepatocellular carcinoma, thereby causing a major health problem worldwide. In this study, the authors demonstrated that Ostm1 plays an inhibitory role in HBV proteins production, RNA expression, and DNA replication. However, Ostm1 has no effect on the activities of the four HBV promoters; instead, it binds to HBV RNA and recruits RNA exosome to promote HBV RNA degradation. The authors further demonstrated that anti-HBV activity of Ostm1 is independent on interferon signaling pathway. In conclusion, this study revealed a distinct mechanism underlying the repression of HBV replication, and suggested that Ostm1 is a potential therapeutic agent for HBV infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Chunqiang Ma",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wei Xu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qingyu Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China wukailang@whu.edu.cn jwu@whu.edu.cn."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "Journal of virology",
        "year": 2020
    },
    "ITY1DneS": {
        "id": "ITY1DneS",
        "title": "Characterizing spatiotemporal patterns of air pollution in China: A multiscale landscape approach",
        "abstract": "Abstract   China’s tremendous economic growth in the past three decades has resulted in a number of environmental problems, including the deterioration of air quality. In particular, fine particulate matter (PM) has received increasing attention from scientists, governmental agencies, and the public due to its adverse impacts on human health. Monitoring the spatiotemporal patterns of air pollution is important for understanding its transport mechanisms and making effective environmental policies. The main goal of this study, therefore, was to quantify the spatial patterns and movement of air pollution in China at annual, daily, and hourly scales, so that the underlying drivers could be better understood. We used remote sensing data and landscape metrics together to capture spatiotemporal signatures of air pollution. Our results show that, at the annual scale, PM 2.5  concentrations in China increased gradually from 1999 to 2011, with the highest concentrations occurring in the North China Plain as well as the middle and lower reaches of the Yangtze River Basin. The total population affected by air pollution was about 975 million in 2010 (about 70% of China’s population). Our more detailed analysis on daily and hourly scale further revealed that a heavy air pollution event occurred, expanded, aggregated, and finally dissipated over Northern China during Oct. 6–12, 2014, suggesting that the Beijing-Tianjin-Hebei region a center of severe pollution. Crop stalks burning in agricultural areas in this region seemed to be one of the leading drivers, along with coal burning and transportation emissions. Our study demonstrates that spatial pattern analysis with landscape metrics is effective for analyzing source-sink dynamics of air pollution and its potential drivers. Our findings of major source areas and movement trajectories should be useful for making air pollution control policies to improve China’s air quality.",
        "keywords": "",
        "authors": [
            {
                "name": "Yupeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            }
        ],
        "venue": "Ecological Indicators",
        "year": 2017
    },
    "VYrI4AFW": {
        "id": "VYrI4AFW",
        "title": "Formal Verification of Controller Synthesis Based on Incompletely Specified Finite State Machine Model",
        "abstract": "IP traffic prediction plays an important role in network-layout, traffic-management, as well as the emphasis of traffic-project, congestion-control and network management. Poor prediction performance would be acquired generally as a result of intense ...",
        "keywords": [
            "machine model",
            "network management",
            "incompletely specified finite state",
            "important role",
            "poor prediction performance",
            "ip traffic prediction",
            "formal verification",
            "computational complexity",
            "graph theory",
            "time complexity",
            "automata",
            "finite state machine",
            "algorithm design and analysis",
            "manganese",
            "finite state machines",
            "process control"
        ],
        "authors": [
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Zhengyi Liu",
                "org": ""
            },
            {
                "name": "Ying Lu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "IITA '08 Proceedings of the 2008 Second International Symposium on Intelligent Information Technology Application - Volume 03",
        "year": 2008
    },
    "lhY5Hwpa": {
        "id": "lhY5Hwpa",
        "title": "Bovine PrPC directly interacts with alphaB-crystalline.",
        "abstract": "We used a bovine brain cDNA library to perform a yeast two-hybrid assay with bovine mature PrP(C) as bait. The screening result showed that alphaB-crystalline interacted with PrP(C). The interaction was further evaluated both in vivo and in vitro with different methods, such as immunofluorescent colocalization, native polyacrylamide-gel electrophoresis, and IAsys biosensor assays. The results suggested that alphaB-crystalline may have the ability to refold denatured prion proteins, and provided first evidence that alphaB-crystalline is directly associated with prion protein.",
        "keywords": [],
        "authors": [
            {
                "name": "Guihong Sun",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, PR China."
            },
            {
                "name": "Mingxiong Guo",
                "org": ""
            },
            {
                "name": "Ao Shen",
                "org": ""
            },
            {
                "name": "Fanghua Mei",
                "org": ""
            },
            {
                "name": "Xiaoxue Peng",
                "org": ""
            },
            {
                "name": "Rui Gong",
                "org": ""
            },
            {
                "name": "Deyin Guo",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Po Tien",
                "org": ""
            },
            {
                "name": "Gengfu Xiao",
                "org": ""
            }
        ],
        "venue": "FEBS letters",
        "year": 2005
    },
    "Dx2L5f8Z": {
        "id": "Dx2L5f8Z",
        "title": "Human immunodeficiency virus-1 Rev protein activates hepatitis C virus gene expression by directly targeting the HCV 5'-untranslated region.",
        "abstract": "Coinfection with human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) accelerates hepatitis C disease progression; however, the mechanism underlying this effect is unknown. Here, we investigated the role of HIV-1 in HCV gene expression and the mechanism involved in this regulation. We discovered that HIV-1 Rev protein activates HCV gene expression. We further revealed that Rev binds to the internal loop of the HCV 5'-untranslated region (5'-UTR) to stimulate HCV IRES-mediated translation.",
        "keywords": [
            "hiv-1",
            "untranslated region",
            "hcv",
            "rna structure",
            "coinfection"
        ],
        "authors": [
            {
                "name": "Jing Qu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhenhua Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qi Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Youxing Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qiong Ding",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fang Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zishu Pan",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Biao He",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "FEBS letters",
        "year": 2011
    },
    "e7yf37AP": {
        "id": "e7yf37AP",
        "title": "Research on automatic meshing for elliptic hatchway corner",
        "abstract": "This paper proposes the automatic meshing method for the elliptic hatchway corners.Such meshing system is developed based on PCL which is the secondary development language of MSC.Patran software.The hot spot stresses on elliptical hatchway corners with different sizes are analyzed and compared with stresses on circular ones with corresponding sizes.The results show that the hot spot stresses on elliptical hatchway corners are much smaller than stresses on circular ones.",
        "keywords": [
            "PCL(Patran Command Language)",
            "mesh generation",
            "hatchway corner"
        ],
        "authors": [
            {
                "name": "XIE Tian-ru",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "LIN Yong",
                "org": "Ship Inspection Bureau of Zhejiang Province,Hangzhou ,China"
            }
        ],
        "venue": "Ship & Boat",
        "year": 2012
    },
    "TcwLEm7L": {
        "id": "TcwLEm7L",
        "title": "The unique HCV genotype distribution and the discovery of a novel subtype 6u among IDUs co-infected with HIV-1 in Yunnan, China.",
        "abstract": "The Yunnan province is the epicenter of HIV-1 epidemics in China and a center for drug trafficking to the other parts of the world. In six prefectures of this province, a total of 132 IDUs were recruited to determine the sero-prevalence of HCV and HIV-1 and the positive rates were 93.94% and 68.18%, respectively (P<0.001). Co-infection with HCV and HIV-1 was found among 89 IDUs, of whom several HCV fragments were amplified and sequenced. Sequences of the HCV 5'NCR-C and NS5B region were determined from 82 IDUs. Phylogenetic analyses showed consistent genotyping among 80 IDUs. Among them HCV genotypes 1a, 1b, 3a, 3b, 6a, 6n, and a tentatively assigned novel 6u subtype were found in 1 (1.25%), 16 (20%), 19 (23.75%), 24 (30%), 4 (5%), 9 (11.25%) and 7 (8.75%) individuals, respectively. In two IDUs, genotyping results were discordant, suggesting mixed HCV infections or recombination. The proportion of patients with HCV 1b tended to decrease from the north to south and from the east to west in this province. Genotype 3 and 6 strains were more frequent in the southern prefectures. The novel subtype 6u strains were only detected in Dehong which borders Myanmar. Our findings showed a unique pattern of HCV genotype distribution, which is similar to that in the southeastern Asian countries but distinct from that among the general population in China. Routes of drug trafficking and the resulting high prevalence of HIV-1 infection may have contributed to this pattern of HCV genotype distribution.",
        "keywords": [
            "co-infection idus",
            "genotypes",
            "hcv",
            "hiv-1",
            "research methodology",
            "clinical research",
            "epidemiology",
            "measurement",
            "behavior",
            "developing countries",
            "health",
            "public health",
            "prevalence"
        ],
        "authors": [
            {
                "name": "Xueshan Xia",
                "org": ""
            },
            {
                "name": "Ling Lu",
                "org": ""
            },
            {
                "name": "Kok Keng Tee",
                "org": ""
            },
            {
                "name": "Wenhua Zhao",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Jing Yu",
                "org": ""
            },
            {
                "name": "Xiaojie Li",
                "org": ""
            },
            {
                "name": "Yixiong Lin",
                "org": ""
            },
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": ""
            },
            {
                "name": "Curt H Hagedorn",
                "org": ""
            },
            {
                "name": "Yutaka Takebe",
                "org": ""
            }
        ],
        "venue": "Journal of medical virology",
        "year": 2008
    },
    "obibcZWX": {
        "id": "obibcZWX",
        "title": "Short Communication Origin of highly pathogenic H5N1 avian influenza virus in China and genetic characterization of donor and recipient viruses",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": ""
            },
            {
                "name": "Sahibzada T. Rasool",
                "org": ""
            },
            {
                "name": "Degui Song",
                "org": ""
            },
            {
                "name": "Chengliang Zhu",
                "org": ""
            },
            {
                "name": "Qian Hao",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": "State Key Laboratory of Virology|College of Life Sciences|Wuhan University"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology|College of Life Sciences|Wuhan University"
            }
        ],
        "venue": "",
        "year": 0
    },
    "e8xJqXZp": {
        "id": "e8xJqXZp",
        "title": "Study on transcription regulation network in rheumatoid arthritis via bioinformatics analysis",
        "abstract": "Rheumatoid arthritis (RA) is a systemic, inflammatory autoimmune disease with irreversible joint destruction. It is a form of autoimmunity, however, its cause is incompletely known. The objective of this study was to identify potential transcription regulation between transcription factors and differentially expressed genes in RA by using the microarray data and transcriptional network analysis. In addition, their underlying molecular mechanisms were also explored by Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment. Our results showed that JUN, ETS2, CREB1, PPARG, and SPI1 were crucial transcription factors in our transcriptome networks and these transcription factors could regulate the DEGs expression to involve in RA by promoting or inhibiting effect. For example, JUN could promote FN1 expression; ETS2 promoted FLT1 expression; CREB1 promoted CD4 expression and inhibited F3 expression; PPARG could also inhibit MMP9 expression; SPI1 promoted CSF3R expression. In addition, four significant pathways were identified associated with RA development, including hematopoietic cell lineage, pathways in cancer, MAPK signaling pathway, antigen processing and presentation. ETS2 and PPARG could inhibit hematopoietic cell lineage pathway; ETS2, Jun, and SPI1 promoted the pathway in cancer; CREB1 suppressed MAKP signaling pathway, but promoted antigen processing and presentation. However, further experiments are still needed to confirm the conclusion.",
        "keywords": [
            "Rheumatoid arthritis",
            "bioinformatics",
            "network"
        ],
        "authors": [
            {
                "name": "jie chen",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "jun xia",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "siqun wang",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "yibing wei",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "jianguo wu",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "gangyong huang",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "feiyan chen",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            },
            {
                "name": "jingcheng shi",
                "org": "Shanghai Fudan Univ, Huashan Hosp, Dept Orthoped, Shanghai 200040, Peoples R China"
            }
        ],
        "venue": "AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY",
        "year": 2012
    },
    "D1QnFNHO": {
        "id": "D1QnFNHO",
        "title": "Reform in examination mode of high education",
        "abstract": "The paper presents reform in examination mode of high education.Student can select many courses in a semester by his ability.He applies for examination at the end of semester.Examination system generates one electronic test paper instead of many test papers according to examination courses.The paper includes single choices corrected by computer,short answer questions,and essay questions,programming questions and drawing questions corrected by teacher.",
        "keywords": [
            "examination mode",
            "test paper generation",
            "high education"
        ],
        "authors": [
            {
                "name": "Liu Zhengyi",
                "org": " Anhui university,Hefei,,China"
            },
            {
                "name": "Wu Jianguo",
                "org": " Anhui university,Hefei,,China"
            },
            {
                "name": "Li Wei",
                "org": " Anhui university,Hefei,,China"
            }
        ],
        "venue": "China Modern Educational Equipment",
        "year": 2011
    },
    "8iFnNiMw": {
        "id": "8iFnNiMw",
        "title": "Mapping QTLs Controlling Beneficial Fatty Acids Based on the Embryo and Maternal Plant Genomes in Brassica napus L.",
        "abstract": "This study was mainly carried out to detect the quantitative trait loci (QTLs) located simultaneously in embryo and maternal plant nuclear genomes for beneficial fatty acid contents of rapeseed under different environments by using a mapping model and mapping populations from a cross of ‘Tapidor’ × ‘Ningyou7.’ Eight, three, six, seven and three QTLs respectively for palmitic, oleic, linoleic, linolenic and eicosenoic acid contents were identified and subsequently mapped on chromosomes A1, A3, A4, A6, A8, A9, C1, C3, C5, C7, C8 and C9. Among them, 12 QTLs were major ones that could respectively explain more than 10 % of phenotypic variation. Two specific genomic regions on A8 and C3 were associated with several QTLs relating to multiple fatty acid contents. Some of the markers such as HBr015 and JICB0633 showed tight linkage with the QTLs, which could be used for improving the fatty acid component(s) of rapeseed.",
        "keywords": [
            "Brassica napus L.",
            " Fatty acid component",
            " Quantitative trait locus (QTL)",
            " Embryo nuclear genome",
            " Maternal plant nuclear genome"
        ],
        "authors": [
            {
                "name": "juan wen",
                "org": "zhejiang university"
            },
            {
                "name": "jianfeng xu",
                "org": "zhejiang university"
            },
            {
                "name": "yan long",
                "org": "College of Plant Science and Technology,Huazhong Agriculture University,Wuhan,People’s Republic of China"
            },
            {
                "name": "haiming xu",
                "org": "zhejiang university"
            },
            {
                "name": "jianguo wu",
                "org": "zhejiang a f university"
            },
            {
                "name": "j meng",
                "org": "College of Plant Science and Technology,Huazhong Agriculture University,Wuhan,People’s Republic of China"
            },
            {
                "name": "chunhai shi",
                "org": "zhejiang university"
            }
        ],
        "venue": "Journal of the American Oil Chemists' Society",
        "year": 2015
    },
    "iZa6GB8w": {
        "id": "iZa6GB8w",
        "title": "Embedded Control System of Marine Valve Based on Redundancy CAN Bus",
        "abstract": "The features of general marine valve control are analyzed.It is stated by the author that the embedded micro controller can be adopted into marine valve and the redundancy CANBUS based marine valve control system is composed together with host industrial computer.The whole control system is constituted by the host computer and multiple nodes which contain the embedded micro controller.The signals of valve opening and of motor current are collected by the controller.The use of redundancy CANBUS can realize the communication between host computer and controller nodes,easy to achieve the closed-loop control in the marine valve.The design of hardware and software of the control system are introduced in detail.",
        "keywords": [
            "valve control",
            "redundancy CAN bus",
            "embedded system"
        ],
        "authors": [
            {
                "name": "HUANG Zi-ying",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "ZHANG Zhi-min",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            }
        ],
        "venue": "Instrumentation Technology",
        "year": 2011
    },
    "bF55BXZX": {
        "id": "bF55BXZX",
        "title": "Serum BlyS, anti-BlyS and BlyS-immune complex determination in patients with autoimmune diseases",
        "abstract": "Objective To investigate the prevalence of B lymphocyte stimulator(BlyS) , anti-BlyS (BlyS-Ab) and its specific immune complex (BlyS-IC) in patients with autoimmune diseases (AID) , and explores the role of the above items in pathogenesis of these diseases. Methods By optimizing experimental conditions, we had established three types of ELJSA methods for serum levels of BlyS, BlyS-Ab and BlyS-IC , followed by assessing their methodology and serving them as a tool for clinical research. Results The lower detection limit of ELJSA method for BlyS was determined to be at 0. 4μg/L At a concentration of 3. 2～400. 0μg/L, there was a good learner correlations for BlyS (r > 0. 99). The intra-assay precision, namely average of coefficient values of BlyS-Ab was 7. 4% , and the specific inhibition rate for BlyS-Ab by series concentration of BlyS was up to 83. 3% . Clinical investigation revealed that serum levels of BlyS, BlyS-Ab and BlyS-IC were significantly higher in patients with AID including SLE, RA, MCTD and other medicine cases with positive ANA (i. e. nephritis, allergic purpurics and pulmonary disease etc. ) than that in normal control ( In comparison with titers of ANA, serum BlyS and BlyS-Ab level were parallel increases) , but no correlation was found in this investigation between serum BlyS levels and certain fluorescent nuclear-type of ANA. Conclusions Detection methods for human serum BlyS, BlyS-Ab and BlyS-IC are successfully established. The assay results were specific, sensitive and reliable. Higher levels of serum BlyS were found in patients with multifarious AID, at the sametime, serum levels of ANA, BlyS-Ab as well as BlyS-IC are also increased. Therefore, this investigation is potentially helpful to diagnose AID, and plays a significant role to illustrate pathogenesis of these diseases.",
        "keywords": [
            "B lymphocyte stimulator",
            "Autoimmune diseases",
            "Autoantibody",
            "Immune complex"
        ],
        "authors": [
            {
                "name": "YU Wei",
                "org": ". Laboratory of Clinical Immunology, Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command of People's Liberation Army, Nanjing , China"
            },
            {
                "name": "WEI Li",
                "org": ". Laboratory of Clinical Immunology, Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command of People's Liberation Army, Nanjing , China"
            },
            {
                "name": "FENG Li",
                "org": ". Laboratory of Clinical Immunology, Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command of People's Liberation Army, Nanjing , China"
            },
            {
                "name": "LI Xiao-jun",
                "org": ". Laboratory of Clinical Immunology, Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command of People's Liberation Army, Nanjing , China"
            },
            {
                "name": "WU Jian-guo",
                "org": ". Laboratory of Clinical Immunology, Center of Medical Laboratory Science, Nanjing General Hospital of Nanjing Command of People's Liberation Army, Nanjing , China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Medicine",
        "year": 2006
    },
    "krqcOXl2": {
        "id": "krqcOXl2",
        "title": "Different Household Livelihood Strategies and Influencing Factors in the Inner Mongolian Grassland",
        "abstract": "Household livelihood strategies affect grassland ecosystem services and the herder’s well-being. Understanding different household livelihood strategies and influencing factors is crucial for sustainable development in pastoral areas. We surveyed 241 households in the typical grassland region of Inner Mongolia to classify the different types of household livelihood strategies using income-based cluster analysis and to identify the major influencing factors of household livelihood strategies with partial least squares structural equation modeling (PLS-SEM). Our study has several findings. First, according to household income sources, there are five types of household livelihood strategies in this region, including breeding only small livestock (S), breeding mainly small livestock (SL), breeding mainly large livestock (LS), breeding only large livestock (L), and not breeding livestock (N), with the S strategy as the most dominant household livelihood strategy in this region. Second, among the five types of household livelihood strategies, the LS strategy had the highest household income (323,200 Chinese yuans) while the N strategy had the lowest household income (68,540 Chinese yuans). Third, among the five types of livelihood capitals, manufactured capital and natural capital had more substantial influences on household livelihood strategies. Manufactured capital directly influenced household livelihood strategies, while natural capital affected household livelihood strategies either directly or indirectly through manufactured capital. Our results suggest that the LS strategy would be the most economically profitable among the five household livelihood strategies in the typical grassland region of Inner Mongolia.",
        "keywords": "",
        "authors": [
            {
                "name": "Yang Liu",
                "org": ""
            },
            {
                "name": "Qing Zhang",
                "org": ""
            },
            {
                "name": "Qingfu Liu",
                "org": ""
            },
            {
                "name": "Yongzhi Yan",
                "org": ""
            },
            {
                "name": "Wanxin Hei",
                "org": ""
            },
            {
                "name": "Deyong Yu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Sustainability",
        "year": 2020
    },
    "uQmbKuPO": {
        "id": "uQmbKuPO",
        "title": "Regulation of HIF-1 <i>α</i> to expression of N-myc downstream regulated gene 1 in colorectal carcinoma",
        "abstract": "Plasmid expressing small interfering RNA (siRNA) against HIF-1a (pSilence-2.1-U6-siRNA) was constructed and transfected into\n LS174T cells in hypoxia condition. After expression of siRNA against HIF-1 α in LS174T cells, expressions of HIF-1 α and N-myc downstream regulated gene 1 (NDRG1) gene were inhibited significantly. HIF-1 α a transcripts were positive in 67.7% (42/62) and 44.4% (8/18) of colorectal adenocarcinoma and adenoma, respectively. The\n mean percentage of cells with positive hybridization of HIF-1 α mRNA increases with the development from Duke stage A to stage C+D (p < 0.05). The positive staining rate of NDRG1 protein was significant higher in colorectal adenocarcinoma group than that\n in colorectal adenoma group (p α transcripts was positively correlated with the level of NDRG1 protein (p < 0.05) during colorectal tumor progression. HIF-1a and its down stream gene NDRG1 may play roles in tumor progression of\n human colorectal carcinoma.",
        "keywords": [],
        "authors": [
            {
                "name": "Duanyi Zhao",
                "org": "Department of Colorectal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071 Hubei China"
            },
            {
                "name": "Zhisu Liu",
                "org": "Department of Colorectal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071 Hubei China"
            },
            {
                "name": "Congqing Jiang",
                "org": "Department of Colorectal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071 Hubei China"
            },
            {
                "name": "Gassimou Bangoura",
                "org": "Department of Colorectal Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071 Hubei China"
            },
            {
                "name": "Kailang Wu",
                "org": "College of Life Sciences, Wuhan University/National Key Laboratory of Virology, Wuhan, 430072 Hubei China"
            },
            {
                "name": "Jianguo Wu",
                "org": "College of Life Sciences, Wuhan University/National Key Laboratory of Virology, Wuhan, 430072 Hubei China"
            }
        ],
        "venue": "Wuhan University Journal of Natural Sciences",
        "year": 2007
    },
    "BZUfOB4Z": {
        "id": "BZUfOB4Z",
        "title": "Research Situation and Application of Aluminum Foams Prepared by PCM Method",
        "abstract": "Internal and external research situation of aluminum foams prepared by PCM(powder compacting method) was introduced in the paper.The influence factors on foaming behavior and pore structure of aluminum foams were discussed.The process and application of large-scale aluminum foams and composite structure were described.The further development and existing problems of aluminum foams prepared by PCM were presented as well.",
        "keywords": [
            "foaming",
            "application",
            "PCM process",
            "aluminum foams"
        ],
        "authors": [
            {
                "name": "PAN Qiang",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            },
            {
                "name": "WANG Fang",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            },
            {
                "name": "YOU Xiao-hong",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            },
            {
                "name": "ZHANG Shu-ling",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            },
            {
                "name": "WANG Lu-cai",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science and Technology,Taiyuan ,China"
            }
        ],
        "venue": "Aluminium Fabrication",
        "year": 2011
    },
    "FQcwn4lK": {
        "id": "FQcwn4lK",
        "title": "Analysis of Residual Ultimate Strength for Damaged Ship's Hull",
        "abstract": "The study of this paper is to analysis the certain bulker carrier and VLCC tanker on the residual ultimate strength using the progressive collapse methodology defined in IACS common structural rules and with the considering the asymmetrical cross-section model of hull girder and heeling changes due to two damage assumptions of collision and grounding which damage extents based on ABS and DNV rules,also the influence of assumed damage extents is evaluated.The outcome of this paper can be the valuable reference for the development of Harmonized Common Structural Rule.",
        "keywords": [
            "Collision and grounding",
            "Ship structural rules",
            "Damaged hull",
            "Damage extent",
            "Residual ultimate strength"
        ],
        "authors": [
            {
                "name": "SHU Xin",
                "org": "Zhejiang university of technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Zhejiang university of technology,Hangzhou ,China"
            },
            {
                "name": "HONG Ying",
                "org": "Shanghai institute of China Classification Society,Shanghai ,China"
            }
        ],
        "venue": "Marine Technology",
        "year": 2012
    },
    "5gCKnYBD": {
        "id": "5gCKnYBD",
        "title": "RAPID POSITIONING METHOD FOR SCANNED BALLOT IMAGE RECOGNITION",
        "abstract": "In OCR-based election voting system,how to achieve rapid positioning in image recognition is still an important issue.To solve this problem,a positioning method for scanned ballot image recognition is proposed based on taking full account the design of the ballot and utilising the image processing technology.The method uses relevant position data recorded during the ballot design,pre-processes the ballot image to find a definite reference point,then extracts the position data in the ballot design,converts it to an image position data relative to the reference point position,and searches the table lines with the position data,so as to determine the accurate position of the image to be recognised or captured.Experimental results show that this method has high speed in positioning,and is feasible to be applied to election votes for scanned ballot image recognition.",
        "keywords": [
            "Vote Ballot Scan Image recognition Position"
        ],
        "authors": [
            {
                "name": "Hu Lirui",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,Anhui,China;School of Computer Science and Technology,Nantong University,Nantong ,Jiangsu,China;School of Computer Science and Technology,Anhui University,Hefei ,Anhui,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,Anhui,China;School of Computer Science and Technology,Anhui University,Hefei ,Anhui,China"
            }
        ],
        "venue": "Computer Applications and Software",
        "year": 2012
    },
    "gr2BMpWc": {
        "id": "gr2BMpWc",
        "title": "“What Kind of a Science is Sustainability Science?” An Evidence-Based Reexamination",
        "abstract": "Sustainability science (SS), rooted in multiple disciplines, has been developing rapidly during the last two decades and become a well-recognized new field of study. However, the “identity” of SS remains unclear. Therefore, this study was intended to help synthesize the key characteristics of SS by revisiting the question raised by the leading sustainability scientist, Robert Kates (2011): “What kind of a science is sustainability science?” Specifically, we reviewed the literature in SS, and developed a synthesis of definitions and core research questions of SS, using multiple methods including change-point detection, word cloud visualization, and content and thematic analyses. Our study has produced several main findings: (1) the development of SS exhibited an S-shaped growth pattern, with an exponential growth phase through to 2012, and a asymptotic development phase afterwards; (2) ten key elements from the existing definitions of SS were identified, of which understanding “human–environment interactions” and “use-inspired” were most prominent; and (3) sixteen core questions in SS were derived from the literature. We further proposed an eight-theme framework of SS to help understand how the sixteen questions are related to each other. We argue that SS is coming of age, but more integrative and concerted efforts are still needed to further consolidate its identity by developing a coherent and rigorous scientific core.",
        "keywords": "",
        "authors": [
            {
                "name": "Xuening Fang",
                "org": "Beijing Normal University"
            },
            {
                "name": "Xuening Fang",
                "org": "Beijing Normal University"
            },
            {
                "name": "Bingbing Zhou",
                "org": "Arizona State University"
            },
            {
                "name": "Xingyue Tu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Qun Ma",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            }
        ],
        "venue": "Sustainability",
        "year": 2018
    },
    "KrUgkSSW": {
        "id": "KrUgkSSW",
        "title": "Study on the Immunology and Cytogenetics of 73 Cases with Acute Leukemia",
        "abstract": "Objective To To evaluate the clinical significance of combined detection of immunophenotype and cytogenetics in the diagnosis of acute leukemia.Methods Immunophenotyping was performed by three/four color flow cytometry analysis with CD 45/SSC and karyotype analysis was performed by R banding technique, respectively.Results The coincidence rate was 89.0% between morphology and immunology. Immunophenotyping corrected two cases misdiagnosed for M7 and chromosome examination corrected 4 cases misdiagnosed for M3 of acute myeloid leukemia (AML) by morphology, respectively. CD13(92.0%) and CD33(94.0%) was specifically expressed in AML who had 55% clonal chromosome abnormality, including 59% specific clonal chromosome abnormality. CD13 (100%) and CD33 (100%) was specially expressed in M3 with t(15;17) translocation. CD19 (100%), CD34 (100%) and t(8;21) translocation was specially expressed in M2b. CD14(25%) was specially expressed in M5 who had 50% t/del(11q23) clonal chromosome abnormality. Lymphoid lineage associated antigents CD7 (24.0%), CD19 (12%), CD10 (6.0%) were easily found in AML. It was 73% that the ratio of clonal chromosome abnormality in CD7+ AML, which was obviously higher than that in CD7- AML (P<0.05). B-ALL had 83% clonal chromosome abnormality, including 53% specific clonal chromosome abnormality, which were 71% and 60% in T-ALL, respectively. Myeloid lineage associated antigents CD13 (57.0%), CD33 (38%) also could existed in ALL.Conclusion The combination of immunophenotype and chromosome examination is helpful to diagnosing AL, evaluating prognosis and revealing the characteristics of cell biology. The diagnosis of the special types such as M0, M3 and M7 of AL must depend on immunophenotype and chromosome analysis.",
        "keywords": [
            "Immunophenotype",
            "Leukemia",
            "Acute",
            "Chromosome"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Institute of Immunology, Zhejiang University, Hangzhou, Zhejiang, , China."
            },
            {
                "name": "XIA Da-jing",
                "org": "Institute of Immunology, Zhejiang University, Hangzhou, Zhejiang, , China."
            }
        ],
        "venue": "Zhejiang Journal of Preventive Medicine",
        "year": 2008
    },
    "mvH0mM46": {
        "id": "mvH0mM46",
        "title": "Simulating land use change with agent-based models: progress and prospects",
        "abstract": "Land use and land cover change is fundamentally important for studying global environmental change and sustainability because it has great impacts on biodiversity,ecosystem processes,atmospheric circulation,environmental quality,climate change,etc.Simulation modeling has been important in the study of land use dynamics and,recently,agent-based models(ABMs) have been developed and applied in this field.An ABM is composed of a set of agents interacting in a common environment.Agents have the following characteristics: goal-directed,autonomy,social abilities,reactivity and pro-activities.They can interact with one another and with the environment and complete tasks autonomously without human intervention.They exhibit goal-directed behavior,have their own problem-solving capabilities,and are able to interact in order to reach an overall goal.Agents perceive,produce,transform and manipulate objects in the environment and reach autonomy cooperatively by sensing activity and modifying their environment.ABMs have an intuitive appeal for simulating complex human-involved processes.They are able to explicitly model individual decision makers and their interactions and simulate complex human behavior and decision processes as they are affected by socioeconomic factors.In urban studies,ABMs have been integrated with human behavior and decisions with cellular automata architecture.In ecology,individual-based models(IBMs) were developed at the end of 1980s which are similar to ABMs in several ways.Now ABMs have been used in economics,sociology,psychology,finance,urban simulation,and other fields.Major platforms include SWARM,RePast,Ascape,and CORMAS.In this paper,we attempt to outline the basic concepts and general modeling framework of ABMs,discuss the pros and cons of these models,and explore their future directions in simulating land use change,urban dynamics,and ecological processes.",
        "keywords": [
            "land use dynamic",
            "agent based model",
            "complex sciences",
            "progress and prospects"
        ],
        "authors": [
            {
                "name": "TIAN Guang-Jin",
                "org": ""
            },
            {
                "name": "WU Jian-Guo",
                "org": "Center for Landscape Ecology and Sustainability Science,Beijing Normal University,Beijing ,China;Sino-US Center for Conservation,Energy and Sustainability Science,Inner Mongolia University,Hohhot ,China;School of Life Sciences & Global Institute of Sustainability,Arizona State University,Tempe,AZ 85287,USA"
            }
        ],
        "venue": "Acta Ecologica Sinica",
        "year": 2008
    },
    "mI4EJEww": {
        "id": "mI4EJEww",
        "title": "The Treatment and Trend Analysis of Municipal Solid Waste in China",
        "abstract": "The treatment methods of municipal solid waste in China were introduced briefly,and current status of municipal solid waste treatment and its trend were studied.The results show that the major treatment method in China is landfill,with the treatment ratio accounting for 95% of the total.The capacity of sanitary landfill is lower,and there exist big differences in treatment levels all over China,so the regional difference exists in municipal solid waste treatment.Based on the correlations of transportation amount of solid waste with other driving factors,such as GDP,per capita GDP and non-agriculture population,the estimating models were built.The models were used to forecast future municipal solid waste generating amount in different scenarios.The forecasting result of non-agriculture population is more close to reality than GDP or per capita GDP-based models.",
        "keywords": [
            "municipal solid waste",
            "trend",
            "forecast",
            "treatment"
        ],
        "authors": [
            {
                "name": "DU Wu-peng",
                "org": ""
            },
            {
                "name": "GAO Qing-xian",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG En-chen",
                "org": "Shenyang Environmental Engineering Design and Research Institute,Shenyang ,China"
            },
            {
                "name": "MIAO Qi-long",
                "org": "Nanjing University of Information Sciences & Technology,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2006
    },
    "ObjbGwKH": {
        "id": "ObjbGwKH",
        "title": "Inhibition of SARS-CoV gene expression by adenovirus-delivered small hairpin RNA.",
        "abstract": "Severe acute respiratory syndrome (SARS) is a highly contagious and lethal disease caused by a new type of coronavirus, SARS-associated coronavirus (SARS-CoV). Currently, there is no efficient treatment and prevention for this disease. We constructed recombinant adenoviral vectors that can express shRNAs, which inhibited the expression of SARS-CoV genes effectively in mammalian cells.In this study, we designed several plasmids that express small hairpin RNA molecules (shRNA) specifically targeting to the genes encoding for the SARS-CoV nucleocapsid (N) protein and envelope (E) protein, respectively. Effective shRNA molecules to the viral genes were screened and identified, and then constructed into adenovirus vectors. The effects of adenovirus-delivered small hairpin RNA on SARS-CoV gene expression were determined by RT-PCR, Western blot, and luciferase activity assays.The levels of viral mRNAs and viral proteins of the targets were significantly decreased or completely inhibited in cell lines after being infected with the recombinant adenoviruses that expressed specific shRNA molecules.Since many cell types can be efficiently infected by adenovirus, recombinant adenoviruses could serve as an alternative powerful tool for shRNA delivery and for gene suppression, especially when the targeted cells are resistant to transfection by DNA or RNA. With availability of high titers of adenoviruses and uniform and rapid infection, this approach would have foreseeable wide applications both in experimental biology and molecular medicine.",
        "keywords": [
            "nucleocapsid protein",
            "small hairpin rna",
            "sars-cov",
            "envelope protein",
            "adenovirus",
            "cell line",
            "adenoviral vector",
            "gene expression"
        ],
        "authors": [
            {
                "name": "Xue Zhang",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Xin Yue",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Intervirology",
        "year": 2007
    },
    "ClWsk7pB": {
        "id": "ClWsk7pB",
        "title": "Contrary to Common Observations in the West, Urban Park Access Is Only Weakly Related to Neighborhood Socioeconomic Conditions in Beijing, China",
        "abstract": "Parks provide critical ecosystem services to urban residents. Park access critically determines how parks are used by residents. Many existing studies, which mostly have been conducted in developed countries, reported that park access disproportionately benefits the socioeconomically advantaged groups. To test if this observation also holds true in developing countries, we examined the park access and its relationship with socioeconomic conditions in Beijing, China. We used a buffering method and a road network-based analysis to calculate the park access of 130 neighborhoods, and applied the Pearson correlation to examine how neighborhood park access is related to socioeconomic conditions. Our results showed that (1) the park access decreased from 76% in the downtown areas to 24% in the suburbs; (2) the correlation coefficients (r) between socioeconomic conditions and park access were all smaller than 0.3 (p u003c 0.05)—that is, explaining less than 8% of the variability. Our study indicated that neighborhood socioeconomic conditions were only weakly associated with park access in Beijing and did not support the common phenomenon in western countries. Such a contradiction might be explained by the fact that park planning in Beijing is funded and administered by the city government and influenced by the central government’s policy, whereas in most developed countries market sectors play a critical role in park planning. Our research suggested that urban planning funded by governments, when aimed at improving the wellbeing of all urban residents, may effectively reduce potential environmental inequalities.",
        "keywords": "",
        "authors": [
            {
                "name": "Xingyue Tu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Ganlin Huang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            }
        ],
        "venue": "Sustainability",
        "year": 2018
    },
    "yeU80i57": {
        "id": "yeU80i57",
        "title": "Calibration and prediction of amino acids in stevia leaf powder using near infrared reflectance spectroscopy.",
        "abstract": "The use of stevia as animal feed additive has been researched over the years, but how to rapidly predict its amino acid contents has not been studied yet by using near-infrared reflectance spectroscopy. In the present study, 301 samples of stevia leaf powder were defined as the calibration set from which calibration models were optimized, and the performance of prediction was evaluated. Compared with other mathematical treatments, the models developed with the \"1, 12, 12, 1\" treatment, combined with modified partial least-squares regression and standard normal variance with de-trending, had a significant potential in predicting amino acid contents, such as threonine, serine, etc. Six spectral regions were found to possess large spectrum variation and show high contribution to calibration models. From the present study, the calibration models of amino acids in stevia were successfully developed and could be applied to quality control in feed processing, breeding selection and mutant screening.",
        "keywords": [
            "calibration",
            "near infrared reflectance spectroscopy (nirs)",
            "animal feed additive",
            "modified partial least squares regression (mpls)",
            "amino acid",
            "stevia"
        ],
        "authors": [
            {
                "name": "Guan Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ruiguo Wang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Alfred Julius Quampah",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhengqin Rong",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of agricultural and food chemistry",
        "year": 2011
    },
    "ciMsugRu": {
        "id": "ciMsugRu",
        "title": "QTL mapping based on the embryo and maternal genetic systems for non-essential amino acids in rapeseed ( Brassica napus L.) meal: QTL mapping of amino acids in rapeseed",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "juan wen",
                "org": ""
            },
            {
                "name": "jianfeng xu",
                "org": ""
            },
            {
                "name": "yan long",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "haiming xu",
                "org": ""
            },
            {
                "name": "j meng",
                "org": ""
            },
            {
                "name": "chunhai shi",
                "org": ""
            }
        ],
        "venue": "Journal of the Science of Food and Agriculture",
        "year": 2015
    },
    "UAXEe5aM": {
        "id": "UAXEe5aM",
        "title": "Regional landscape futures to moderate projected climate change: a case study in the agro-pastoral transitional zone of North China",
        "abstract": "Changes in land systems have been shown to affect regional climate, but minimal attention has been paid to landscape patterns as adaptation strategies to climate change. In this study, we introduce alternative futures analysis and coupled land-atmosphere modeling to investigate the effect of landscape patterns on moderating projected climate change in northern China. Three future landscape scenarios are developed, and their impacts on regional climate in the context of climate change are examined. A reference scenario, Business-as-Usual, follows recent landscape trajectory; the Conservation scenario puts greater emphasis on ecosystem protection and restoration to ultimately achieve sustained socioeconomic development; the Degradation scenario ignores current policy to allow broad cropland expansion. The landscape impacts on regional climate under two representative concentration pathways (RCPs) are substantial and dependent on background climate. The Conservation scenario shows considerable decreases in near-surface temperature and extensive increases in rainfall during summer as compared with Business-as-Usual under RCP8.5 (i.e., a high emissions scenario), thus representing a preferred landscape pattern for climate moderation. However, trade-offs between temperature reduction and rainfall enhancement exist under RCP4.5 (i.e., a low-to-moderate emissions scenario), which necessitates careful evaluation. Finally, the Degradation scenario leads to the highest temperature and lowest rainfall among the three alternative futures under both climate conditions. Our study underlines the importance of landscape design/planning as an effective way to moderate climate change, and provides useful scientific information for making land use policies.",
        "keywords": [
            "Alternative futures analysis",
            " Climate change scenarios",
            " Landscape impacts on climate",
            " Regional climate modeling",
            " Semi-arid region"
        ],
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Institute of Ecology and Biodiversity, School of Life Sciences, Shandong University, Qingdao, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing, China"
            },
            {
                "name": "Renqing Wang",
                "org": "Institute of Ecology and Biodiversity, School of Life Sciences, Shandong University, Qingdao, China"
            },
            {
                "name": "Jianmin Qiao",
                "org": "School of Geography and Environment, Shandong Normal University, Jinan, China"
            }
        ],
        "venue": "Regional Environmental Change",
        "year": 2020
    },
    "NwQK96qw": {
        "id": "NwQK96qw",
        "title": "Exploration and practice of inquiring teaching for the experiments of genetics]",
        "abstract": "Aiming for fostering talents with the sense and ability of creation, the current wave of experimental teaching reform demands significant improvements in genetics. We proposed a train of thoughts about transforming the testing and verifying experiments of genetics into inquiring forms with comprehensive or designing property, and gave some examples to carry out inquiring teaching for the experiments of genetics.",
        "keywords": [
            "experiments of genetics",
            "inquiring teaching",
            "sense of creation",
            "ability of creation"
        ],
        "authors": [
            {
                "name": "Jian-Fu Xiao",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2009
    },
    "Gf8euUD3": {
        "id": "Gf8euUD3",
        "title": "[Soil CO 2 ,CH 4 and N 2 O Fluxes from Alpine Meadows on the Plateau of Southern Qinghai Province During Snow Cover Period and Growing Seasons].",
        "abstract": "To understand the fluxes of soil greenhouse gases from Alpine meadows on the Qinghai-Tibet plateau during non-growing season, a static chamber method was used to sample gases of soil CO, CH and NO from alpine meadow on the plateau of Southern Qinghai province during snow cover period, and gas chromatography was used to analyze concentrations of these gases. The results showed that soil CO flux was 1.33 g·(m·h), soil CH flux was -0.19 mg·(m·h), and soil NO flux was 0.21 mg·(m·h) when the snow depth was 9-10 cm on March 3 and 4 during the prevalence period of snow cover; soil CO flux was 4.70 g·(m·h) ,and soil NO flux was 0.24 mg·(m·h), and soil CH flux was -1.23 mg·(m·h) when the snow depth was 8-9 cm on April 30 during the end period of snow cover. And soil CO and NO fluxes were low or negative, soil CH flux was negative and its absolute value was low when the snow depth was less than 4 cm during snow cover period. In addition, soil CO or NO flux was positively correlated with the snow depth, and soil CH flux was negatively correlated with the snow depth (<0.05). Additionally, soil CO or NO flux was negatively correlated with CH fluxes, and soil CO was positively correlated with soil NO flux. In addition, soil CO flux was the highest during the growing season, followed by the end period of snow cover, and it was the lowest during the prevalence period of snow cover; soil NO flux was high during the growing season, followed by the end period of snow cover, and it was the lowest during the prevalence period of snow cover; soil CH flux was negative, and its absolute value was higher during the growing season than other seasons, and it was the lowest during the prevalence period of snow cover. The results suggested that the change in snow cover would influence the fluxes of soil greenhouse gases from alpine meadow on the Qinghai-Tibet plateau.",
        "keywords": [
            "Qinghai-Tibet Plateau",
            "alpine meadow",
            "climate change",
            "flux",
            "snow cover",
            "soil greenhouse gases"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Chinese Research Academy of Environmental Sciences, Beijing 100012, China."
            },
            {
                "name": "Qiao-Fu Zhou",
                "org": "Chinese Research Academy of Environmental Sciences, Beijing 100012, China."
            }
        ],
        "venue": "Huan jing ke xue= Huanjing kexue",
        "year": 2016
    },
    "g7n5qfLl": {
        "id": "g7n5qfLl",
        "title": "Research and Development of Multi-Channel Signal Collector",
        "abstract": "Takes AT89C51 microcontroller as the core,the collector gathers multichannel signal by expanding peripheral I/O interface,and the processing result is sent out through serial.Having developed a low-cost,simple-structure,reliable,and efficient multi-channel signal acquisition devices by using 51-microcontroller's operating characteristics analysis and mathematical statistics.",
        "keywords": [
            "bit-operation",
            "statistical sampling",
            "multi-channel signal acquisition",
            "AT89C51"
        ],
        "authors": [
            {
                "name": "TAO Bao-zhuang",
                "org": "Computer School,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHANG Yi-chao",
                "org": "Computer School,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Computer School,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Computer School,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2008
    },
    "ECIoomGI": {
        "id": "ECIoomGI",
        "title": "Concept of ecosystem management and its essential elements]",
        "abstract": "Ecosystem management originates from the tradition fields of natural resources management and utilization, and develops in the 1990's. Based on our best understanding of the ecosystem composition, structure and function, and in definite spatiotemporal scales, it integrates human values and social-economic principles into managing ecosystems to resotre and/or sustain ecosystem integrity and sustainability. Ecosystem management requires the collection of field data and the monitoring of ecosystem dynamics at multiple scales. The essential elements of ecosystem management include clear management goals, definite ecological boundaries and units, sound ecological understanding, appropriate scale and hierarchic structure, understanding of ecosystem uncertainty, adaptive management, cooperation between agency and individuals, and viewing human and its value as ecosystem components. The goal of ecosystem management focuses on ecosystem sustainbility.",
        "keywords": [
            "ecosystem management",
            "ecosystem sustainability",
            "scale"
        ],
        "authors": [
            {
                "name": "H Ren",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            },
            {
                "name": "J Wu",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            },
            {
                "name": "S Peng",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            }
        ],
        "venue": "Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban",
        "year": 2000
    },
    "dIgDLkvs": {
        "id": "dIgDLkvs",
        "title": "Decomposition Analysis on Changes of Energy-related CO_2 Emission in Inner Mongolia",
        "abstract": "Based on the extended Kaya identity,this paper uses the Log-mean Divisia index method to construct a complete decomposition model,and identifies the factors that influence the changes of energy-related CO2 emission in Inner Mongolia during the period of 1999-2008,which are energy structure,energy intensity,economic structure,economic activity and population change.The results show that economic activity has the largest positive effects on CO2 emission changes in all the factors,and its contribution rate is up to 89.22%,and other factors sorted by the absolute value of contribution rate from large to small are economic structure(17.01%),energy intensity(-6.71%),population change(2.78%)and energy structure(-2.30%).These results may shed light on possible development trajectories and energy transition in Inner Mongolia with a high potential for growth,which maily includes improving energy efficiency,adjusting industrial structure,optimizing energy structure and implementing green GDP accounting.",
        "keywords": [
            "energy consumption",
            "Inner Mongolia",
            "CO2 emission"
        ],
        "authors": [
            {
                "name": "Qian Guixia",
                "org": "School of Economics & Management,Inner Mongolia University,Hohhot ,China;Sino-US Center for Conservation,Energy and Sustainability Science in Inner Mongolia,Hohhot ,China"
            },
            {
                "name": "Zhang Yipin",
                "org": "School of Economics & Management,Inner Mongolia University,Hohhot ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "Sino-US Center for Conservation,Energy and Sustainability Science in Inner Mongolia,Hohhot ,China;School of Life Sciences and Global Institute of Sustainability,Arizona State University,Tempe AZ 85287 USA"
            }
        ],
        "venue": "Technology Economics",
        "year": 2010
    },
    "ACc2kh5Q": {
        "id": "ACc2kh5Q",
        "title": "Antiviral activity of lycorine against Zika virus in vivo and in vitro.",
        "abstract": "The emergence and re-emergence of Zika virus (ZIKV), is a cause for international concern. These highly pathogenic arboviruses represent a serious health burden in tropical and subtropical areas worldwide. Despite these burdens, antiviral therapies do not exist, and inhibitors of ZIKV are therefore urgently needed. To elucidate the anti-ZIKV effect of lycorine, we used reverse transcription-quantitative real-time PCR (qRT-PCR), immunofluorescence,  blot, and plaque forming assay to analyse viral RNA (vRNA), viral protein, progeny virus counts, and validated inhibitors in vitro using a variety of cell lines. Additionally, we found that lycorine acts post-infection according to time-of-addition assay, and inhibits RdRp activity. Lycorine protected AG6 mice against ZIKV-induced lethality by decreasing the viral load in the blood. Due to its potency and ability to target ZIKV infection in vivo and in vitro, lycorine might offer promising therapeutic possibilities for combatting ZIKV infections in the future.",
        "keywords": [
            "AG6 mice",
            "Alkaloid",
            "Antiviral",
            "Lycorine",
            "RdRp inhibitor",
            "ZIKV"
        ],
        "authors": [
            {
                "name": "Huini Chen",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China."
            },
            {
                "name": "Zizhao Lao",
                "org": "Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China."
            },
            {
                "name": "Jiangtao Xu",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China."
            },
            {
                "name": "Zhaoxin Li",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China."
            },
            {
                "name": "Haishan Long",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China."
            },
            {
                "name": "Detang Li",
                "org": "Department of Pharmacy, First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China."
            },
            {
                "name": "Luping Lin",
                "org": "Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510060, China."
            },
            {
                "name": "Xiaohong Liu",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510000, China."
            },
            {
                "name": "Liangwen Yu",
                "org": "Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. Electronic address: fisherman@gzucm.edu.cn."
            },
            {
                "name": "Weiyong Liu",
                "org": "Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: wyliu@hust.edu.cn."
            },
            {
                "name": "Geng Li",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China; Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. Electronic address: lg@gzucm.edu.cn."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China. Electronic address: wu9988@vip.sina.com."
            }
        ],
        "venue": "Virology",
        "year": 2020
    },
    "MPMa1Se6": {
        "id": "MPMa1Se6",
        "title": "Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells.",
        "abstract": "Hypoxia-inducible factor 1 (HIF-1) emerges as a crucial player in tumor progression. However, its role in hepatocellular carcinoma (HCC), especially its relation with global DNA methylation patterns in HCC under hypoxic tumor microenvironment is not completely understood. Methionine adenosyltransferase 2A (MAT2A) maintains the homeostasis of S-adenosylmethionine (SAM), a critical marker of genomic methylation status. In this study, we investigated the link between HIF-1α and MAT2A as a mechanism responsible for the change in genomic DNA methylation patterns in liver cancer under hypoxia conditions. Our results showed that hypoxia induces genomic DNA demethylation in CpG islands by reducing the steady-state SAM level both in vitro and in vivo. In addition, HIF-1α and MAT2A expression is correlated with tumor size and TNM stage of liver cancer tissues. We further showed that hypoxia-induced MAT2A expression is HIF-1α dependent and requires the recruitment of p300 and HDAC1. We also identified an authentic consensus HIF-1α binding site in MAT2A promoter by site-directed mutagenesis, electrophoretic mobility shift assay, and chromatin immunoprecipitation assay. Taken together, we show for the first time that hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells. These findings provide new insights into our understanding of the molecular link between genomic DNA methylation and tumor hypoxia in HCC.",
        "keywords": [],
        "authors": [
            {
                "name": "Quanyan Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Li Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yuhong Zhao",
                "org": "Guangdong College of Pharmacy(Guangdong College of Pharmacy,Guangdong Pharmaceutical University),Guangzhou,China"
            },
            {
                "name": "Jin Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Dongfeng Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jiwei Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yueming He",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhonglin Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhisu Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Molecular cancer therapeutics",
        "year": 2011
    },
    "Tk5PrUEz": {
        "id": "Tk5PrUEz",
        "title": "IL-27, a cytokine, and IFN-��1, a type III IFN, are coordinated to regulate virus replication through type I IFN",
        "abstract": "IL-27, a member of the IL-12 family, plays a critical role in the control of innate and adaptive immune responses. IFN-��1, a member of the type III IFN family, shows antiviral abilities. In this study, we investigated the effects of IL-27 and IFN-��1 on the replication of hepatitis B virus (HBV), a major pathogen associated with a high risk for cirrhosis, liver failure, and hepatocellular carcinoma. We revealed that HBV infection activates IL-27 expression and IFN-��1 production and demonstrated that viral-activated IL-27 and IFN-��1 are coordinated to inhibit HBV replication. Initially, HBV infection upregulates IL-27 expression, which, in turn, stimulates IFN-��1 production through regulating ERK1/2 signaling and by enhancing NF-��B nuclear translocation to bind to the IFN-��1 promoter. Moreover, IL-27-activated IFN-l1 upregulates IFN-��1 receptor (IL-28R1 and IL-10R��) activity, resulting in the activation of the STAT1/2 pathway, which, in turn, induces the expression of IFN-stimulated genes, including IFN-inducible dsRNA-activated protein kinase, oligoadenylate synthetase 1, and IFN-induced GTP-binding protein 1 and, finally, inhibits HBV protein expression and viral capsid-associated DNA replication. More interestingly, we also revealed that type I IFN (IFN-��) is also involved in the downregulation of HBV replication mediated by IL-27. Thus, we identified a previously unknown mechanism by which IL-27 and IFN-��1 are coordinated to regulate virus replication through type I IFN. Copyright ? 2014 by The American Association of Immunologists, Inc.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yanhua Cao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Rui Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wei Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Chengliang Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yi Yu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yu Song",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qing Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Lan Bai",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of immunology (Baltimore, Md. : 1950)",
        "year": 2014
    },
    "FmBfMKND": {
        "id": "FmBfMKND",
        "title": "Responses of soil organic carbon and nitrogen decomposition to changing temperature and related research methods: a review]",
        "abstract": "In this paper, the researches about the relationships of soil carbon and nitrogen storage with temperature, and the responses of soil carbon and nitrogen decomposition to the spatiotemporal differentiation of temperature, increasing air temperature, and soil freezing-thawing were summarized, and the uncertainty and determination errors of related research methods were discussed. Climate warming could promote soil carbon and nitrogen decomposition and soil CO2 emission within a short period, but not always accelerate the decomposition of soil carbon and nitrogen in a long-term. Therefore, to give a reasonable interpretation on the discrepancies of previous studies, a systematic analysis on the mechanisms about the effects of changing temperature on the decomposition of soil carbon and nitrogen should be made, and the differences about the long-term and short-term responses of soil carbon and nitrogen decomposition to the changing temperature, as well as the influences of research method, vegetation, soil, and climate conditions on the research results should also be fully understood.",
        "keywords": [
            "decomposition of soil organic matter.",
            "soil carbon and nitrogen cycling",
            "climate change"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban",
        "year": 2007
    },
    "oTWWhtdP": {
        "id": "oTWWhtdP",
        "title": "Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication",
        "abstract": "Interleukin-32 was recently identified as a pro-inflammatory cytokine produced by T-lymphocytes, natural killer cells, epithelial cells, and blood monocytes. IL-32 is induced by IFN-gamma in a time-dependent manner suggesting a role for IL-32 in innate and adaptive immune responses. In this study we present evidence that Human immunodeficiency virus promotes interleukin-32 production at both mRNA and protein levels. Our results showed that there is a 74% increase in the serum levels of IL-32 among HIV patients as compared to healthy individuals. There was a three-fold increase in the promoter activity of the IL-32 in the present infections HIV clone. This increase in IL-32 promoter activity was substantiated by increased IL-32 mRNA and protein levels. We have also demonstrated that IL-32 suppresses HIV replication. Our results show that HIV LTR activity was increased by more than six-folds when endogenous IL-32 was knocked down by IL-32-specific siRNA whereas it decreased by one-fold when IL-32 was over expressed in the cells. Similarly a more than two-fold increase and a 50% decrease in HIV p24 values were noted when IL-32 was knocked down and when IL-32 was over expressed in the cells, respectively. Our present work shows that raised IL-32 levels in HIV infection may in turn hamper HIV replication; one of the protective mechanisms of nature.",
        "keywords": [
            "sirna",
            "interleukin-32",
            "hiv",
            "epithelial cell",
            "interleukin 32",
            "adaptive immunity"
        ],
        "authors": [
            {
                "name": "Sahibzada T. Rasool",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Heng Tang",
                "org": "Hubei Provincial Center for Disease Control and Prevention, Wuhan, PR China"
            },
            {
                "name": "Jianmei Wu",
                "org": "Wuhan Blood Center, Wuhan, PR China"
            },
            {
                "name": "Wei Li",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Jingwen Zhang",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Huang Xioa Xing",
                "org": "Medical Virology Laboratory, The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            }
        ],
        "venue": "Immunology Letters",
        "year": 2008
    },
    "Pqyb0mWP": {
        "id": "Pqyb0mWP",
        "title": "IL-32: a host proinflammatory factor against influenza viral replication is upregulated by aberrant epigenetic modifications during influenza A virus infection.",
        "abstract": "Our previous studies with clinical data analysis have shown that the proinflammatory factor IL-32 is activated in response to influenza virus infection. However, little is known about how influenza virus induces IL-32 production, and the role of IL-32 in the host immune responses during viral infection remains unclear. In this study, we show that IL-32 production is stimulated by influenza A virus or dsRNA in human PBMCs from healthy volunteers. We demonstrate that the NF-κB and CREB pathways play key roles in the activation of IL-32 production in response to influenza virus infection in A549 human lung epithelial cells. We then show that aberrant epigenetic modifications in the IL32 promoter are important in the transcriptional regulation of IL-32 expression. Interestingly, one CpG demethylation within the CREB binding site increases the binding of CREB to the promoter, which is followed by IL32 transcriptional activation in influenza A virus-infected cells. Overexpression assays combined with RNA interference show that DNA methyltransferases DNMT1 and DNMT3b are critical for IL32 promoter methylation and gene silencing before viral infection. We have demonstrated the anti-influenza virus function of IL-32. Assays for each of the six IL-32 isoforms (α, β, γ, δ, ε, and ζ) during influenza virus infection indicated that all the isoforms have antiviral activity, with different inhibitory rates, and that the effect of IL-32γ is strongest. Our results indicate that the elevated IL-32 levels triggered by influenza virus infection in turn hamper viral replication.",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wei Sun",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Li Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fang Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yongkui Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jiali Fang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wenjing Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of immunology (Baltimore, Md. : 1950)",
        "year": 2010
    },
    "dE9azVtq": {
        "id": "dE9azVtq",
        "title": "Advances in the Effects of Climate Change on the Distribution of Plant Species and Vegetation in China",
        "abstract": "Forecasting plant species and vegetation distribution patterns following climate change accurately is crucial for the realizing the effects of climate change on the biodiversity and formulating the adaptation strategy to conservation biodiversity following changing in climate.In recent years,the effects of the climate change on the distribution of plant species and vegetation were analyzed extensively in China.The climate change scenarios,various forecasting models and the effects of climate change on the distribution of plant species and vegetation were reviewed.The improper and uncertainness of various methods used to analyzing the effects were diseussed,future research emphases were suggested.Generally,the climate change scenarios were too single to be used in analyzing the impacts of climate change.There were no comparison between different forecasting models of plant species and vegetation distribution.The soil and biological factors were not considered in choosing environmental factors in models.The quantity of plant species was too limited to study the effects of climate change on distribution of plant species in China.The climate change would cause the distribution of some plant species decreasing,even some plant species vanished,and some plant species distribution space increasing in China.In future researches,more attention shoud be paid to the accuracy of climate change scenarios and the comparison of the various forecasting models,and the soil and biological factors should be considered.Comprehensively the influence of climate change on plant species diversity and abundance should be investigated in future.",
        "keywords": [
            "distribution of plant species",
            "prediction model",
            "climate change"
        ],
        "authors": [
            {
                "name": "LV Jia-jia",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2009
    },
    "albspWwv": {
        "id": "albspWwv",
        "title": "Quantifying Spatiotemporal Patterns and Ecological Effects of Urbanization: A Multiscale Landscape Approach",
        "abstract": "",
        "keywords": [
            "simulation models"
        ],
        "authors": [
            {
                "name": "jianguo wu",
                "org": "the school of life"
            },
            {
                "name": "alexander buyantuyev",
                "org": "inner mongolia university"
            },
            {
                "name": "g darrel jenerette",
                "org": "university of california riverside"
            },
            {
                "name": "jennifer litteral",
                "org": "the school of life"
            },
            {
                "name": "kaesha neil",
                "org": "the school of life"
            },
            {
                "name": "weijun shen",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "",
        "year": 2011
    },
    "qrjFd8OY": {
        "id": "qrjFd8OY",
        "title": "Construction of a Health Management System Suitable for China's National Conditions",
        "abstract": "Now health management at medical institutions are on the position of opening up the medical market,which is a view point to increase medical demand and promote medical consumption belonging to a gentrification management.The ways for an active and effective promotion of health management and a cost control of health maintenance are to plan a scientific and standardized system of health management,to establish a value prerequisite beneficial to all ordinary people and set up a health management standard convenient for everyone to participate,to break up the regulation that relies solely on medical insurance to control the costs of health care,and to combine health management with establishment of a harmonious medical surroundings based on the present status of our health management.",
        "keywords": [
            "Construction",
            "Health management",
            "System"
        ],
        "authors": [
            {
                "name": "LU Jian-hua",
                "org": ",et al.College of Medical Administration,Nanjing Medical University,Jiangsu Province,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ",et al.College of Medical Administration,Nanjing Medical University,Jiangsu Province,Nanjing ,China"
            },
            {
                "name": "WU Jing-na",
                "org": ",et al.College of Medical Administration,Nanjing Medical University,Jiangsu Province,Nanjing ,China"
            }
        ],
        "venue": "Chinese General Practice",
        "year": 2009
    },
    "RCX3YXOQ": {
        "id": "RCX3YXOQ",
        "title": "ROS accumulation and antiviral defence control by microRNA528 in rice.",
        "abstract": "MicroRNAs (miRNAs) are key regulators of plant-pathogen interactions. Modulating miRNA function has emerged as a new strategy to produce virus resistance traits(1-5). However, the miRNAs involved in antiviral defence and the underlying mechanisms remain largely elusive. We previously demonstrated that sequestration by Argonaute (AGO) proteins plays an important role in regulating miRNA function in antiviral defence pathways(6). Here we reveal that cleavage-defective AGO18 complexes sequester microRNA528 (miR528) upon viral infection. We show that miR528 negatively regulates viral resistance in rice by cleaving L-ascorbate oxidase (AO) messenger RNA, thereby reducing AO-mediated accumulation of reactive oxygen species. Upon viral infection, miR528 becomes preferentially associated with AGO18, leading to elevated AO activity, higher basal reactive oxygen species accumulation and enhanced antiviral defence. Our findings reveal a mechanism in which antiviral defence is boosted through suppression of an miRNA that negatively regulates viral resistance. This mechanism could be manipulated to engineer virus-resistant crop plants.",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Rongxin Yang",
                "org": "Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China"
            },
            {
                "name": "Zhirui Yang",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Shengze Yao",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Shanshan Zhao",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Yu Wang",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Pingchuan Li",
                "org": "Agr & Agri Food Canada, Morden, MB R6M 1Y5, Canada"
            },
            {
                "name": "Xianwei Song",
                "org": "Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China"
            },
            {
                "name": "Lian Jin",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Tong Zhou",
                "org": "Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210014, Jiangsu, Peoples R China"
            },
            {
                "name": "Ying Lan",
                "org": "Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210014, Jiangsu, Peoples R China"
            },
            {
                "name": "Lianhui Xie",
                "org": "Fujian Agr & Forestry Univ, Inst Plant Virol, Fujian Prov Key Lab Plant Virol, State Key Lab Ecol Pest Control Fujian & Taiwan C, Fuzhou 350002, Peoples R China"
            },
            {
                "name": "Xueping Zhou",
                "org": "Zhejiang Univ, Inst Biotechnol, State Key Lab Rice Biol, Hangzhou 310029, Zhejiang, Peoples R China"
            },
            {
                "name": "Chengcai Chu",
                "org": "Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China"
            },
            {
                "name": "Yijun Qi",
                "org": "Tsinghua Univ, Coll Life Sci, Tsinghua Peking Ctr Life Sci, Ctr Plant Biol, Beijing 100084, Peoples R China"
            },
            {
                "name": "Xiaofeng Cao",
                "org": "Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China"
            },
            {
                "name": "Yi Li",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            }
        ],
        "venue": "NATURE PLANTS",
        "year": 2017
    },
    "KUaLUEN3": {
        "id": "KUaLUEN3",
        "title": "Impacts of Amylose Content or Protein Content on Genetic Correlations Between the Weight of Brown Rice and Appearance Quality Traits of Rice",
        "abstract": "A factorial mating design in two environments was conducted by using seven cytoplasm male sterile lines (A) and five restorer lines (R) along with their F1 (A×R) and F2. The unconditional and conditional genetic models and the corresponding statistic methods, including endosperm, cytoplasmic and maternal plant genetic effects, were used for revealing the influences of amylose content (AC) and protein content (PC) of rice to the genetic relationships between the weight of brown rice (WBR) and the appearance quality traits of indica rice (Oryza sativa L.). There were significant relationships between WBR and AC or PC of rice, and the conditional analysis method could be used to exclude the influences of AC and PC to WBR for revealing the real genetic relationships of the pairwise traits. The results from the conditional analysis indicated that AC could positively increase the genetic correlations between WBR and the brown rice length (BRL), the brown rice width (BRW), and the brown rice thickness (BRT), but decrease the genetic correlations between WBR and the ratio of brown rice length to width (RLW) and the ratio of brown rice length to thickness (RLT). PC could decrease the genetic correlations between WBR and BRL, BRW or BRT, and enhance the genetic correlation between WBR and RLW, but there was no visible influence for the genetic correlation between WBR and RLT. After excluding the influence of AC or PC to BRW, the correlation components from the different genetic systems showed that the visible differences could be found between WBR and the appearance quality traits of rice, especially for the cytoplasmic and the maternal additive main effects and their genotype×environment (GE) interaction effects, when compared with the results from the unconditional analysis.",
        "keywords": [
            "indica rice",
            "weight of brown rice",
            "appearance quality trait",
            "amylose content",
            "correlation",
            "protein content"
        ],
        "authors": [
            {
                "name": "GE Guo-ke",
                "org": "1Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "ZHANG Zhi",
                "org": "1Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "SHI Chun-hai",
                "org": "1Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "WU Jian-guo",
                "org": "1Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "YE Zi-hong",
                "org": "1Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            }
        ],
        "venue": "Chinese Journal of Rice Science",
        "year": 2007
    },
    "SP7NkHEY": {
        "id": "SP7NkHEY",
        "title": "EV71 infection induces neurodegeneration via activating TLR7 signaling and IL-6 production.",
        "abstract": "As a neurotropic virus, human Enterovirus 71 (EV71) infection causes hand-foot-and-mouth disease (HFMD) and may develop severe neurological disorders in infants. Toll-like receptor 7 (TLR7) acts as an innate immune receptor and is also a death receptor in the central nervous system (CNS). However, the mechanisms underlying the regulation of TLR7-mediated brain pathogenesis upon EV71 infection remain largely elusive. Here we reveal a novel mechanism by which EV71 infects astrocytes in the brain and induces neural pathogenesis via TLR7 and interleukin-6 (IL-6) in C57BL/6 mice and in human astroglioma U251 cells. Upon EV71 infection, wild-type (WT) mice displayed more significant body weight loss, higher clinical scores, and lower survival rates as compared with TLR7-/- mice. In the cerebral cortex of EV71-infected mice, neurofilament integrity was disrupted, and inflammatory cell infiltration and neurodegeneration were induced in WT mice, whereas these were largely absent in TLR7-/- mice. Similarly, IL-6 production, Caspase-3 cleavage, and cell apoptosis were significantly higher in EV71-infected WT mice as compared with TLR7-/- mice. Moreover, EV71 preferentially infected and induced IL-6 in astrocytes of mice brain. In U251 cells, EV71-induced IL-6 production and cell apoptosis were suppressed by shRNA-mediated knockdown of TLR7 (shTLR7). Moreover, in the cerebral cortex of EV71-infected mice, the blockade of IL-6 with anti-IL-6 antibody (IL-6-Ab) restored the body weight loss, attenuated clinical scores, improved survival rates, reduced the disruption of neurofilament integrity, decreased cell apoptotic induction, and lowered levels of Caspase-3 cleavage. Similarly, in EV71-infected U251 cells, IL-6-Ab blocked EV71-induced IL-6 production and cell apoptosis in response to viral infection. Collectively, it's exhibited TLR7 upregulation, IL-6 induction and astrocytic cell apoptosis in EV71-infected human brain. Taken together, we propose that EV71 infects astrocytes of the cerebral cortex in mice and human and triggers TLR7 signaling and IL-6 release, subsequently inducing neural pathogenesis in the brain.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhen Luo",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Rui Su",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Yicong Liang",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Xiaofeng Zeng",
                "org": "School of Forensic Medicine, Kunming Medical University, Kunming, China."
            },
            {
                "name": "Muhammad Adnan Shereen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Nadia Bashir",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Ling Zhao",
                "org": "State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2019
    },
    "zz34bdnR": {
        "id": "zz34bdnR",
        "title": "DEVELOPMENTAL GENETIC ANALYSIS FOR CRUDE FIBER CONTENT AND CRUDE ASH CONTENT OF RAPESEED MEAL IN TWO DIFFERENT GROWING YEARS: DEVELOPMENTAL GENETICS OF RAPESEED MEAL QUALITY TRAITS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "chunhai shi",
                "org": ""
            },
            {
                "name": "muralitottekkaad variath",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "guolin chen",
                "org": ""
            },
            {
                "name": "li zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Food Quality",
        "year": 2011
    },
    "ACEqzQf6": {
        "id": "ACEqzQf6",
        "title": "The Potential Effects of Climate Change on the Distributions of Seven Arbors Plants in China",
        "abstract": "It is crucial to understand rationally the effects of climate change on the distribution of species for the conservation of biodiversity. To conserve effectively plants biodiversity under climate change, the effects of climate change on the distributions of Qinling Fir (Abies chensiensis), Qilian Savin (Sabina przewalskii), Zhennan (Phoebe zhennan), Sergeant Spruce (Picea brachytyla), China Horsetailtree (Rhoiptelea chiliantha), Manyseeded Euptelea (Euptelea pleiospermn) and China Katsuratree (Cercidiphyllum japonicum) in China was analyzed using the CART (classification and regression tree) model and climate change scenarios of A2 and B2. The results showed that climate change in China would cause decrease in the current distribution of these plants. It would cause a decrease in the new distribution or total distribution region of China Katsuratree, China Horsetailtree, Zhennan, and Qilian Savin from periods of 1991-2020 to periods of 2081-2100. It would also cause decrease in the new distribution and total distribution region of Qinling Fir from periods of 1991-2020 to periods of 2021-2050 year or a increase from periods of 2051-2100 to periods of 2021-2050 year. It would cause an increase in the new distribution or total distribution region of other plants increase from periods of 1991-2020 year to periods of 2081-2100 year. They were higher in A2 scenario than that in B2 scenario. Additionally, under climate change, the southeast of current distribution regions of Horsetailtree would reduce. Their new distribution regions would expand towards west, southwest, north or northeast of the current distribution regions. The southeast or east of current distribution regions of Qinling Fir would reduce. Their new distribution regions would expand towards west or northwest or north or southwest of current distribution regions. The northeast, southeast or south or east of current distribution regions of the other plants would reduce. Their new distribution regions of them would expand towards west or southwest of current distribution regions. Changing in current distribution, new distribution or total distribution region of the plants did not consistently change with changing in annual mean temperature or precipitation in China, and some plants were poor related with changing in annual mean temperature or precipitation in China. The linear regression relationship between changing in some plants distribution and annual mean temperature and annual mean precipitation in China were poor. The results indicated that climate change in China would cause changing in spatial distribution pattern of these plants, decrease in current distribution region of them.",
        "keywords": [
            "Zhennan",
            "Endangered plant",
            "Qinling Fir",
            "Qilian Savin",
            "Climate change",
            "Sergeant Spruce",
            "China Horsetailtree",
            "Manyseeded Euptelea",
            "China Katsuratree"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": "Chinese Research Academy of Environmental Sciences, Beijing , China"
            }
        ],
        "venue": "Plant Diversity and Resources",
        "year": 2011
    },
    "t9XoYb8L": {
        "id": "t9XoYb8L",
        "title": "Cullin1 represses systematic inflammasome activation by binding and catalyzing NLRP3 ubiquitination",
        "abstract": "Activation of the NLRP3 inflammasome is a key process of host immune response, the first line of defense against cellular stresses and pathogen infections. However, excessive inflammasome activation damages the hosts, and thus it must be precisely controlled. The mechanism underlying the repression of systematic inflammasome activation remains largely unknown. This study reveals that CUL1, a key component of the SCF E3 ligase, plays a critical role in regulation of the inflammasome. CUL1 suppresses the inflammasome activation in HEK293T cells, inhibits endogenous NLRP3 in macrophages, and represses inflammatory responses in C57BL/6 mice. Under normal physiological conditions, CUL1 interacts with NLRP3 to disrupt the inflammasome assembly, and catalyzes NLRP3 ubiquitination to repress the inflammasome activation. In response to inflammatory stimuli, CUL1 disassociates from NLRP3 to release the repression of NLRP3 inflammasome activation. This work reveals a distinct mechanism underlying the repression of inflammasome activation under physiological conditions and the induction of inflammasome activation in response to inflammatory stimuli, and thus provides insights into the prevention and treatment of infectious and inflammatory diseases.",
        "keywords": [
            "Cullin1",
            "Interleukin-1&#x03B2",
            "",
            "NLRP3 inflammasome complex",
            "Pro-inflammatory cytokines",
            "SCF E3 ubiquitin ligase complex"
        ],
        "authors": [
            {
                "name": "Pin Wan",
                "org": "Wuhan University"
            },
            {
                "name": "Qi Zhang",
                "org": "Wuhan University"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University"
            },
            {
                "name": "Yaling Jia",
                "org": "Wuhan University"
            },
            {
                "name": "Tianci Wang",
                "org": "Wuhan University"
            },
            {
                "name": "Wenbiao Wang",
                "org": "<institution>Institute of Medical Microbiology, Jinan University</institution>, Guangzhou 510632, <country>China</country>"
            },
            {
                "name": "Pan Pan",
                "org": "Wuhan University"
            },
            {
                "name": "Ge Yang",
                "org": "Wuhan University"
            },
            {
                "name": "Qi Xiang",
                "org": "Wuhan University"
            },
            {
                "name": "Siyu Huang",
                "org": "Wuhan University"
            },
            {
                "name": "Qingyu Yang",
                "org": "Wuhan University"
            },
            {
                "name": "Wei Zhang",
                "org": "Wuhan University"
            },
            {
                "name": "Fang Liu",
                "org": "Wuhan University"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University"
            }
        ],
        "venue": "bioRxiv",
        "year": 2018
    },
    "ppnvbIEC": {
        "id": "ppnvbIEC",
        "title": "A review of research on animal model of experimental retinal vein occlusion",
        "abstract": "· Retinal vein occlusion is a common retinal vascular disorder that frequently associated severe vision loss due to its complication. A research actuality on animal model of experimental retinal vein occlusion was reviewed, including photodynamic venous thrombosis, laser photocoagulation to retinal vein, retinal vein electrocoagulation via vitreous body, intravenous thrombin instillation and endothelin-I injection into the posterior vitreous body. Furthermore, three questions were discussed in these animal models which included facility of animal resource procure, breeding and management, model building, easily level and similarity to anthropometric function and metabolism. ·",
        "keywords": [
            "animal model",
            "retinal vein occlusion"
        ],
        "authors": [
            {
                "name": "Xiao-Xu Zhou",
                "org": " Department of Medical Experiment, Wuhan General Hospital, Guangzhou Command Area of Chinese PLA, Wuhan , Hubei Province, China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": " Department of Medical Experiment, Wuhan General Hospital, Guangzhou Command Area of Chinese PLA, Wuhan , Hubei Province, China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2006
    },
    "PsqG1WKp": {
        "id": "PsqG1WKp",
        "title": "Optimization of fermentation medium for glutathione by response surface method",
        "abstract": "Plackett-Burman design was applied to evaluate three important factors affecting glutathione production,which was glucose,peptone and potassium dihydrogen phosphate.Then the Box-Behnken design and the quadratic regression analysis by MINTAB soft were applied to get the optimal levels of the main factors,and the optimal quality concentrations of the variables were obtained as follows: glucose 2.75%,peptone 3.03% and potassium dihydrogen phosphate 0.11%.Under the optimal conditions,the yield of glutathione improved by 48.60% from 98.94 mg/L to 147.02 mg/L.",
        "keywords": [
            "response surface analysis",
            "fermentation",
            "glutathione",
            "optimization"
        ],
        "authors": [
            {
                "name": "GAN Guangdong",
                "org": "Sichuan University of Science & Engineering,Zigong 64300,China"
            },
            {
                "name": "LIU Qingbin",
                "org": "Sichuan University of Science & Engineering,Zigong 64300,China"
            },
            {
                "name": "WU Jianguo",
                "org": "Sichuan University of Science & Engineering,Zigong 64300,China"
            },
            {
                "name": "XIA Bingbing",
                "org": "Sichuan University of Science & Engineering,Zigong 64300,China"
            },
            {
                "name": "ZHANG Jun",
                "org": "Sichuan University of Science & Engineering,Zigong 64300,China"
            }
        ],
        "venue": "China Brewing",
        "year": 2009
    },
    "GHAdlwoG": {
        "id": "GHAdlwoG",
        "title": "Mineralization of Soil Organic Carbon and Its Motivating Factors to the Dragon Spruce Forest and Alpine Meadows of the Qilian Mountains",
        "abstract": "To understand the effects of varying soil temperature and changing water content on the decomposition of soil organic carbon(SOC),an anaerobic incubation experiment with orthogonal experiment in an artificial climatic chamber was conducted.The test of significance of difference and the first order kinetic model were used to investigate how mineralization of soil organic carbon of the slopes under the Qilian Mountains forest(dominated by Picea crassifolia) and alpine meadows was affected by the alpine temperature,soil water content,soil depth,and mountain altitudes.The results show that the effects of varying soil temperature on the cumulative SOC mineralization and mineralization rate and their ratio were the highest;next were the effects of the changing soil water content.At 1% critical level,the cumulative SOC mineralization, mineralization rate,and their ratios were the highest at 35℃.At 5% critical level,the SOC mineralization,mineralization rate,and their ratios in soil water content of 10% were the lowest;there was no significant difference among the different altitudes.At 10% critical level,the SOC mineralization was higher in 0~15 cm soil depth than in 15~35 cm soil depth,and the difference of the mineralization ratio was not significant among different soil depths.SOC mineralization potential increased with the rising soil temperature and declined to the lowest when the soil water content fell to(10%).(The)(rate)(constant)(of)(SOC)(mineralization)(was)(the)(highest) (in)(35℃)((P<0.05)).(Based)(on)(the)(rate)(of) SOC mineralization or its ratio,Q_(10) was 1.5~7.5 from 5℃ to 15℃,1~2 from 15℃ to 25℃,and 1~3 from 25℃ to 35℃.The study indicates that the mineralization rate of SOC under mountain forest and alpine meadows in the Qilian Mountains would increase by 3~10 times if soil water content reached 20%~40% following the changing of temperature from 5℃ to 35℃.",
        "keywords": [
            "Qilian mountains",
            "Altitude",
            "Alpine meadows",
            "Mountain forest",
            "Mineralization of soil organic carbon",
            "Soil water content",
            "Temperature"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "AI Li",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China;Beijing Science and Technology University,Beijing ,China"
            },
            {
                "name": "ZHU Gao",
                "org": "Xishui Conservation Station of the Qilian Mountains Natural Reserve,Zhangye,Gansu Province ,China"
            },
            {
                "name": "TIAN Zi-qiang",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "CHANG Wei",
                "org": "4;Chinese Academy of Environmental Sciences,Beijing ,China;Beijing Forestry University,Beijing ,China"
            }
        ],
        "venue": "Acta Agrestia Sinica",
        "year": 2007
    },
    "mgHosfV5": {
        "id": "mgHosfV5",
        "title": "Ecologically asynchronous agricultural practice erodes sustainability of the Loess Plateau of China.",
        "abstract": "Sustainability of agricultural landscapes depends largely on land-use practices. As one of the most productive and widespread agricultural soils, loess is often deep and easily eroded, posing grand challenges for environmental sustainability around the world. One prime example is the Loess Plateau of China, which has been cultivated for more than 7500 years. Based on long-term data sets, this study demonstrates that the dominant agricultural practice, winter wheat cropping, continues to be the primary driver for the massive soil erosion and landscape modifications on the Loess Plateau. This traditional farming system is asynchronous with the dynamic rhythm between natural vegetation and climate in the region. In particular, the long summer fallow period for winter wheat fields is concurrent with the heavy-rainstorm season, which greatly accelerates soil erosion. Our finding indicates that common land-use practices that have lasted for thousands of years in China are not environmentally sustainable. Agriculture in this region has relied primarily on the continuous \"mining\" of the soil for the past several thousand years but does not have a one-thousand-year future because of myriad environmental and socioeconomic factors associated with soil erosion. To contain soil erosion and promote sustainability on the Loess Plateau, therefore, a change in the agricultural regime is needed to make sure that current and future agricultural practices follow the vegetation-climate rhythm. In addition, to achieve environmental, economic, and social sustainability in this region, multifunctional land-use planning is required to increase landscape diversity and functions (e.g., proper arrangement of crop fields, orchards, and protected areas).",
        "keywords": [
            "soil erosion",
            "loess plateau",
            "land use",
            "ndvi",
            "agriculture",
            "sediment load",
            "china",
            "rainfall erosivity",
            "winter wheat",
            "vegetation-climate rhythm",
            "sustainability",
            "summer fallow",
            "lai"
        ],
        "authors": [
            {
                "name": "Tianming Wang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Xiaojun Kou",
                "org": ""
            },
            {
                "name": "Chadwick Oliver",
                "org": ""
            },
            {
                "name": "Pu Mou",
                "org": ""
            },
            {
                "name": "Jianping Ge",
                "org": ""
            }
        ],
        "venue": "Ecological applications : a publication of the Ecological Society of America",
        "year": 2010
    },
    "gM4VTUM9": {
        "id": "gM4VTUM9",
        "title": "Buckling analysis of orthotropic plate by finite element method",
        "abstract": "A buckling analysis of orthotropic plate under different boundary conditions and different force types was simulated using Patran-Marc finite element software.The stability principle of orthotropic plate under axial compression was obtained by analysing a series of numerical models with different boundary conditions.A local buckling of composite materials was investigated and the local buckling load between the orthotropic plate and fiber reinforced plastic component was compared,also the application characteristic of orthotropic plate buckling theory in components of FRP composite materials was expounded.The conclusion with the local buckling provided a base for design of the local buckling under the axial load for fiber reinforced plastic plate.",
        "keywords": [
            "eigenvalue",
            "buckling",
            "orthotropic plate"
        ],
        "authors": [
            {
                "name": "QU Wen-bin",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "SHAN Lu-yang",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Materials Research and Application",
        "year": 2010
    },
    "h8hbHgfH": {
        "id": "h8hbHgfH",
        "title": "Borna disease virus P protein inhibits nitric oxide synthase gene expression in astrocytes.",
        "abstract": "Borna disease virus (BDV) is one of the potential infectious agents involved in the development of central nervous system (CNS) diseases. Neurons and astrocytes are the main targets of BDV infection, but little is known about the roles of BDV infection in the biological effects of astrocytes. Here we reported that BDV inhibits the activation of inducible nitric oxide synthase (iNOS) in murine astrocytes induced by bacterial LPS and PMA. To determine which protein of BDV is responsible for the regulation of iNOS expression, we co-transfected murine astrocytes with reporter plasmid iNOS-luciferase and plasmid expressing individual BDV proteins. Results from analyses of reporter activities revealed that only the phosphoprotein (P) of BDV had an inhibitory effect on the activation of iNOS. In addition, P protein inhibits nitric oxide production through regulating iNOS expression. We also reported that the nuclear factor kappa B (NF-kappaB) binding element, AP-1 recognition site, and interferon-stimulated response element (ISRE) on the iNOS promoter were involved in the repression of iNOS gene expression regulated by the P protein. Functional analysis indicated that sequences from amino acids 134 to 174 of the P protein are necessary for the regulation of iNOS. These data suggested that BDV may suppress signal transduction pathways, which resulted in the inhibition of iNOS activation in astrocytes.",
        "keywords": [
            "astrocytes",
            "central nervous system",
            "nitric oxide synthase",
            "gene regulation",
            "borna disease virus",
            "phosphoprotein",
            "nf-kappa b"
        ],
        "authors": [
            {
                "name": "Guiqing Peng",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fengmin Zhang",
                "org": "College of Basic Medical Science, Harbin Medical University, Harbin 150081, PR China"
            },
            {
                "name": "Qi Zhang",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Kailang Wu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fan Zhu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2007
    },
    "vBzIBt0V": {
        "id": "vBzIBt0V",
        "title": "Identification and characterization of dwarf 62, a loss-of-function mutation in DLT/OsGRAS-32 affecting gibberellin metabolism in rice.",
        "abstract": "A dwarf mutant, dwarf 62 (d62), was isolated from rice cultivar 93-11 by mutagenesis with γ-rays. Under normal growth conditions, the mutant had multiple abnormal phenotypes, such as dwarfism, wide and dark-green leaf blades, reduced tiller numbers, late and asynchronous heading, short roots, partial male sterility, etc. Genetic analysis indicated that the abnormal phenotypes were controlled by the recessive mutation of a single nuclear gene. Using molecular markers, the D62 gene was fine mapped in 131-kb region at the short arm of chromosome 6. Positional cloning of D62 gene revealed that it was the same locus as DLT/OsGRAS-32, which encodes a member of the GRAS family. In previous studies, the DLT/OsGRAS-32 is confirmed to play positive roles in brassinosteroid (BR) signaling. Sequence analysis showed that the d62 carried a 2-bp deletion in ORF region of D62 gene which led to a loss-of-function mutation. The function of D62 gene was confirmed by complementation experiment. RT-PCR analysis and promoter activity analysis showed that the D62 gene expressed in all tested tissues including roots, stems, leaves and panicles of rice plant. The d62 mutant exhibited decreased activity of α-amylase in endosperm and reduced content of endogenous GA(1). The expression levels of gibberellin (GA) biosynthetic genes including OsCPS1, OsKS1, OsKO1, OsKAO, OsGA20ox2/SD1 and OsGA2ox3 were significantly increased in d62 mutant. Briefly, these results demonstrated that the D62 (DLT/OsGRAS-32) not only participated in the regulation of BR signaling, but also influenced GA metabolism in rice.",
        "keywords": [
            "positional cloning",
            "dlt/osgras-32",
            "gibberellin (ga)",
            "rice (oryza sativa l.)",
            "dwarf 62 (d62)",
            "gene expression",
            "genetic analysis",
            "sequence analysis"
        ],
        "authors": [
            {
                "name": "Wenqiang Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Shili Weng",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yujiang Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Dapeng Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Planta",
        "year": 2010
    },
    "CUGBKbdF": {
        "id": "CUGBKbdF",
        "title": "Bovine PrP C directly interacts with aB-crystalline",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Guihong Sun",
                "org": ""
            },
            {
                "name": "Mingxiong Guo",
                "org": ""
            },
            {
                "name": "Ao Shen",
                "org": ""
            },
            {
                "name": "Fanghua Mei",
                "org": ""
            },
            {
                "name": "Xiaoxue Peng",
                "org": ""
            },
            {
                "name": "Rui Gong",
                "org": ""
            },
            {
                "name": "Deyin Guo",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Po Tien",
                "org": ""
            },
            {
                "name": "Gengfu Xiao",
                "org": ""
            }
        ],
        "venue": "FEBS Letters",
        "year": 2005
    },
    "DxNOLubs": {
        "id": "DxNOLubs",
        "title": "Technological study on production of chitosan by Mucor racemosus fermentation",
        "abstract": "In natural polysaccharides,chitosan is the only massive alkaline amino polysaccharide,which has a series of special functions,and is used widely in food industry,bio-medical materials,textiles industry,the field of environmental protection and so on.The market prospect is very considerable.In this paper Mucor racemosus was chosen as the strain based on the single factor experiments.The effects of influencing factors were detected by fractional factorial design,and three important factors sucrose,NaNO3and time were also selected.The best contents and medium conditions were determined by analyzing central composite design,Response Surface and Contour.The optimum medium and conditions were as follows:inoculation amount(5%),sucrose(64g/L),yeast extract(3g/L),NaNO3(3.5g/L),K2HPO4(1.5g/L),MgSO4(0.1g/L),FeSO4(0.1g/L),at 28℃,with bed rotation speed of 140r/min for 43h.Under these conditions,the production of chitosan by experiment was 1.43g/L.",
        "keywords": [
            "response surface analysis",
            "fermentation",
            "Mucor racemosus",
            "chitosan"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Yancheng College of Textile Technology,Yancheng "
            },
            {
                "name": "WANG Lan",
                "org": "Yancheng College of Textile Technology,Yancheng ;School of Food Science & Technology,Jiangnan University,Wuxi "
            }
        ],
        "venue": "China Food Additives",
        "year": 2011
    },
    "DOOzm0cK": {
        "id": "DOOzm0cK",
        "title": "Analysis of the genetic relationships from different genetic systems between the amylose content and the appearance quality of indica rice across environments",
        "abstract": "",
        "keywords": [
            "amylose content",
            "conditional and unconditional analysis",
            "genetic relationships",
            "indica rice quality traits",
            "genetics"
        ],
        "authors": [
            {
                "name": "Guo-Ke Ge",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Zi-Hong Ye",
                "org": ""
            }
        ],
        "venue": "Genetics and Molecular Biology",
        "year": 2008
    },
    "4UDkg52F": {
        "id": "4UDkg52F",
        "title": "Correction to: Towards Quantitatively Understanding the Complexity of Social-Ecological Systems—From Connection to Consilience",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiao-Bing Hu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Peijun Shi",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Ming Wang",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Tao Ye",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Mark S. Leeson",
                "org": "School of Engineering,University of Warwick,Coventry,UK"
            },
            {
                "name": "Sander E. van der Leeuw",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Ortwin Renn",
                "org": "Stuttgart Research Center for Interdisciplinary Risk and Innovation Studies,University of Stuttgart,Stuttgart,Germany"
            },
            {
                "name": "Carlo Jaeger",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology,Beijing Normal University,Beijing,China"
            }
        ],
        "venue": "International Journal of Disaster Risk Science",
        "year": 2017
    },
    "tnjF3mzI": {
        "id": "tnjF3mzI",
        "title": "Developmental genetic analysis for crude fiber content and crude ash content of rapeseed meal in two different growing years",
        "abstract": "Developmental genetic analyses method for diploid seed quantitative traits was used to determine the unconditional and conditional genetic main effects and genotype×environment interaction effects from embryo, cytoplasm and maternal genetic systems on crude fiber content (CFC) and crude ash content (CAC) of rapeseed meal in two growing years. The results suggested that the performance at most developmental times/stages for CFC and CAC was mainly affected by the genetic main effects. By using the conditional analysis method, for the different genetic systems, CFC and CAC were simultaneously controlled by the genetic effects from three genetic systems, especially for the maternal main effects. Also, the additive effects were more prominent at most developmental times/stages, and the improvement of both traits could be expected in earlier generation(s) in rapeseed breeding programs. The heritability analysis revealed that the maternal heritability was more prominent during seed development times, especially at maturity. Thus, it suggested that maternal plant selection could be utilized to reduce CFC and increase CAC in rapeseed meal breeding programs. The study further suggested Youcai 601 could be used for reducing CFC, while Huashuang 3 and Zhongyou 821 were suitable for increasing CAC in rapeseed, as evidenced from their predicted parent effects. © 2011 Wiley Periodicals, Inc..",
        "keywords": [],
        "authors": [
            {
                "name": "Liping Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Guolin Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Murali Tottekkaad Variath",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of Food Quality",
        "year": 2011
    },
    "bz1eKwL5": {
        "id": "bz1eKwL5",
        "title": "Detecting surface coal mining areas from remote sensing imagery: an approach based on object-oriented decision trees",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoji Zeng",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            },
            {
                "name": "Zhifeng Liu",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            },
            {
                "name": "Chunyang He",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            },
            {
                "name": "Qun Ma",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University, Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing, China"
            }
        ],
        "venue": "Journal of Applied Remote Sensing",
        "year": 2017
    },
    "UPzNa87d": {
        "id": "UPzNa87d",
        "title": "Genetic analysis for protein content in indica rice",
        "abstract": "Analysis of genetic main effects and GE interaction effects for protein content (PC) and protein index (PI) of indica rice\n (Oryza sativa L.) was conducted for two year experimental data by using a genetic model for quantitative traits of seeds in\n cereal crops. Nine cytoplasmic male sterile lines or maintainers as female parents and five restorer lines as male parents\n were used for a NC II mating design in 1995 and 1996. The results indicated that PC and PI traits were simultaneously controlled\n by genetic main effects as well as GE interaction effects. For PC and PI of rice, the embryo interaction effects (embryo additive\n and dominance interaction effects) were important as effects of triploid endosperm, cytoplasm and diploid maternal plant.\n The estimates of narrow-sense heritability for PC and PI of rice were 85.3% and 77.9%, respectively. The interaction heritability\n was found to be larger than the general heritability for PC and PI of rice. Significant relationships for components of different\n genetic effects between PC and PI were found. The GE interaction covariances tended to be positive.",
        "keywords": [
            "embryo genetic effect",
            "genetic covariances",
            "heritabilities",
            "< indica rice",
            "protein"
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang Agricultural University Agronomy Department Hangzhou 310029 China"
            },
            {
                "name": "Jun Zhu",
                "org": "Zhejiang Agricultural University Agronomy Department Hangzhou 310029 China"
            },
            {
                "name": "Xiaoe Yang",
                "org": "Zhejiang Agricultural University Department of Soil Science and Agricultural Chemistry Hangzhou 310029 China"
            },
            {
                "name": "Yunggui Yu",
                "org": "Zhejiang Agricultural University Department of Soil Science and Agricultural Chemistry Hangzhou 310029 China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang Agricultural University Agronomy Department Hangzhou 310029 China"
            }
        ],
        "venue": "Euphytica",
        "year": 1999
    },
    "Vz3xySAo": {
        "id": "Vz3xySAo",
        "title": "Design and implementation of keyboard input method for handwritten Chinese characters",
        "abstract": "A new handwritten Chinese character keyboard input method was designed, and an algorithm of generating strokes intelligently based on fast fuzzy matching was presented. In this method, a Chinese character was simulated on the keyboard by a key list of feature points including up-points, twist-points, middle-points and down-points of each stroke. By constructing a netlike search space of strokes, a key list was converted to a set of stroke lists, so that the keyboard input of the Chinese character was achieved. It is unnecessary to memorize the keys stricken when the user inputs Chinese character into the computer.",
        "keywords": [
            "stroke",
            "finite state machine",
            "Chinese character keyboard input method",
            "Chinese character handwriting input method"
        ],
        "authors": [
            {
                "name": "WU Hai-hui",
                "org": " Ministry of Education Key Laboratory of Intelligent Computing and Signal Processing, Anhui University, Hefei Anhui , China; Management School, Anhui University, Hefei Anhui , China"
            },
            {
                "name": "FAN Qing-lin",
                "org": " Ministry of Education Key Laboratory of Intelligent Computing and Signal Processing, Anhui University, Hefei Anhui , China"
            },
            {
                "name": "WU Jian-guo",
                "org": " Ministry of Education Key Laboratory of Intelligent Computing and Signal Processing, Anhui University, Hefei Anhui , China"
            }
        ],
        "venue": "Journal of Computer Applications",
        "year": 2008
    },
    "25qSvKYC": {
        "id": "25qSvKYC",
        "title": "Epidemiological and Clinical Characteristics of Patients With Coronavirus Disease-2019 in Shiyan City, China.",
        "abstract": "To investigate the early epidemic of COVID-19, a total of 176 confirmed COVID-19 cases in Shiyan city, Hubei province, China were surveyed. Our data indicated that the rate of emergence of early confirmed COVID-19 cases in Hubei province outside Wuhan was dependent on migration population, and the second-generation of patients were family clusters originating from Wuhan travelers. Epidemiological investigation indicated that the reproductive number (R) under containment strategies was 1.81, and asymptomatic SARS-CoV-2 carriers were contagious with a transmission rate of 10.7%. Among the 176 patients, 53 were admitted to the Renmin Hospital of Hubei University of Medicine. The clinical characteristics of these 53 patients were collected and compared based on a positive RT-PCR test and presence of pneumonia. Clinical data showed that 47.2% (25/53) of COVID-19 patients were co-infected with , and COVID-19 patients coinfected with  had a higher percentage of monocytes ( < 0.0044) and a lower neutrophils percentage ( < 0.0264). Therefore, it is important to assess the transmissibility of infected asymptomatic individuals for SARS-CoV-2 transmission; moreover, clinicians should be alert to the high incidence of co-infection with  in COVID-19 patients.",
        "keywords": [
            "COVID-19",
            "Mycoplasma pneumonia",
            "SARS-CoV-2",
            "asymptomatic infections",
            "coinfection"
        ],
        "authors": [
            {
                "name": "Long Liu",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Xu Lei",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Xiao Xiao",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Jing Yang",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Jian Li",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Manshan Ji",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Weixing Du",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Huabing Tan",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Jianyong Zhu",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Bei Li",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Zhixiong Jin",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "Department of Clinical Laboratory, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Zhixin Liu",
                "org": "Department of Infectious Diseases, Department of Respiratory, Renmin Hospital, School of Basic Medical Sciences, Hubei University of Medicine, Shiyan, China."
            }
        ],
        "venue": "Frontiers in cellular and infection microbiology",
        "year": 2020
    },
    "skdAYCzi": {
        "id": "skdAYCzi",
        "title": "Spatial scaling of urban impervious surfaces across evolving landscapes: From cities to urban regions",
        "abstract": "Abstract   Urban impervious surfaces (UIS) influence the structure and function of urban systems, and are widely considered a key indicator of urban environmental conditions. However, the amount and pattern of UIS both change with spatial scale, which complicates the computation and interpretation of UIS as an indicator. A better understanding of the spatial scaling relations of UIS is needed to resolve this predicament. Thus, the main objective of this study was to explore how UIS would change with increasing spatial extent and population size across urban hierarchical levels, using data from the three largest urban agglomerations in China. In addition, a comparative analysis of six world metropolitan regions was conducted to test the generality of the UIS scaling relations. Scalograms and standardized major axis regression were used to investigate the scaling relations with respect to spatial extent and city size, respectively. Our major findings include: (1) the total amount of UIS increased, whereas the percentage of UIS decreased, in a staircase-like fashion when the spatial extent of analysis expanded from within a local city to the entire urban agglomeration; (2) the spatial scaling of UIS followed a rather consistent and tight power law function within a local city, but became less consistent and less tight beyond a local city; (3) the scaling relations of the total amount of UIS were more consistent than those of the percentage of UIS, and the total amount of UIS scaled more tightly with urban area than with urban population size. These findings shed new light on the scale dependence of UIS, suggesting that a multiscale approach should be adopted for quantifying UIS and for using it as an urban environmental indicator.",
        "keywords": "",
        "authors": [
            {
                "name": "Qun Ma",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, School of Sustainability, and Julie Ann Wrigley Global Institute of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, School of Sustainability, and Julie Ann Wrigley Global Institute of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Guohua Hu",
                "org": "Key Lab of Geographic Information Science (Ministry of Education), School of Geographic Sciences, East China Normal University, Shanghai 200241, China"
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2018
    },
    "qXttDbsA": {
        "id": "qXttDbsA",
        "title": "The Design of Electro-Hydraulic Valve Controller Based on CAN Bus",
        "abstract": "The principle of electro-hydraulic valve was analyzed,and the problems in practical use in ships were presented.A new control system of electro-hydraulic valve based on CAN bus was introduced.The valve controller was designed based on CAN bus.MCU of Philips 87C552 and SJA1000 were used to achieve signal communication.The valve controller received the control signals from host computer to control positive and negative rotation of the motor in the executive body and the startup and shutdown of valve could be realized.Simultaneously,the current signal of the motor and position signal of the valve were collected.All of the signals were fed back to host computer by CAN bus.Compared with the traditional electro-hydraulic valve control system,this new control system can avoid wiring.",
        "keywords": [
            "Hall sensor",
            "Valve",
            "MCU",
            "CAN bus",
            "SJA1000"
        ],
        "authors": [
            {
                "name": "ZHANG Peijian",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "DU Wenjing",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "SHENG Weiwei",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            }
        ],
        "venue": "Machine Tool & Hydraulics",
        "year": 2010
    },
    "Oe6Om4RY": {
        "id": "Oe6Om4RY",
        "title": "Developmental genetic analysis for transparency of rice (Oryza sativa L.) at different environments]",
        "abstract": "The developmental behavior of gene expression for transparency of rice (TR) was analyzed from two-year experimental data at different filling stages by using both conditional and unconditional analysis methods for quantitative traits of seeds in cereal crops. It was revealed that the gene expression was most active for the performance of TR at the middle and late filling stages (8-21 d after flowering). The differences of expression at different environments for triploid endosperm nuclear genes, cytoplasmic genes and diploid maternal plant nuclear genes were found for the performance of TR. The phenomena of which some genetic effects were spasmodically expressible were detected among filling stages of rice. Because of the higher additive and cytoplasmic effects along with their interaction effects for TR at the filling stages, the better improving effects for this trait could be expected by selection in rice breeding. Some parents such as Zhenan 3 and 1391 were better than others for improving TR.",
        "keywords": [
            "rice quality",
            "indica rice (oryza sativa l.)",
            "transparency of rice",
            "developmental genetics",
            "genetic effects"
        ],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Long-Jiang Fan",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jun Zhu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ping Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Yi chuan xue bao = Acta genetica Sinica",
        "year": 2002
    },
    "h7hx3kZj": {
        "id": "h7hx3kZj",
        "title": "Optimization of Rack Column Section Based on Stability",
        "abstract": "Using an accurate calculating method on section,stability theory of steel structure axle center pressure and compound optimization method,the paper analyzes and optimizes the stability of the thin section in order to find out the form of section of rack col-umn with the best stability.",
        "keywords": [
            "stability",
            "column with axle center pressure",
            "compound optimization method",
            "rack collumn"
        ],
        "authors": [
            {
                "name": "LI Qiang",
                "org": "Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "ZHONG Hong-lin",
                "org": "Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Logistics Technology",
        "year": 2009
    },
    "oVHWQz66": {
        "id": "oVHWQz66",
        "title": "Isolation, identification, and transcriptional specificity of the heat shock sigma factor sigma32 from Caulobacter crescentus.",
        "abstract": "We report the identification of the Caulobacter crescentus heat shock factor s 32 as a 34-kDa protein that copurifies with the RNA polymerase holoenzyme. The N-terminal amino acid sequence of this protein was determined and used to design a degenerate oligonucleotide as a probe to identify the corresponding gene, rpoH, which encodes a predicted protein with a molecular mass of 33,659 Da. The amino acid sequence of this protein is similar to those of known bacterial heat shock sigma factors of Escherichia coli (41% identity), Pseudomonas aeruginosa(40% identity), andCitrobacter freundii(38% identity). The isolatedC. crescentusgene complements the growth defect of an E. coli rpoH deletion strain at 37&C, and Western blot (immunoblot) analysis confirmed that the gene product is related to theE. coli s 32 protein. The purified RpoH protein in the presence of RNA polymerase core enzyme specifically recognizes the heat shock-regulated promoter P1 of the C. crescentus dnaKgene, and base pair substitutions in either the 210 or 235 region of this promoter abolish transcription. S1 nuclease mapping indicates thatrpoHtranscripts originate from two promoters, P1 and P2, under the normal growth conditions. The P2 promoter is similar to the s 32 promoter consensus, and the P2-specific transcript increases dramatically during heat shock, while the P1-specific transcript remains relatively constant. These results suggest that although the structure and function ofC. crescentus s 32 appear to be very similar to those of its E. coli counterpart, the C. crescentus rpoH gene contains a novel promoter structure and may be positively autoregulated in response to environmental stress. TheCaulobacter crescentuscell cycle generates two different daughter cells: a motile swarmer cell which possesses a single polar flagellum, and a nonmotile stalked cell. The progeny swarmer and stalked cell types differ not only in morphology and motility but also in their programs of gene expression and capacities to reinitiate DNA replication. Formation of the new swarmer cell results from a series of discrete morphogenic events during the cell cycle that occur at one pole of the dividing cell (reviewed in references 8 and 38). This develop- mental sequence depends on completion of successive cell cycle checkpoints, and there is now evidence that the regula-",
        "keywords": [
            "escherichia coli",
            "binding sites",
            "amino acid sequence",
            "dna replication",
            "heat shock proteins",
            "cell cycle checkpoint",
            "molecular mass",
            "base pair",
            "dna probes",
            "gene expression",
            "transcription factors",
            "sigma factor",
            "enzyme",
            "heat shock",
            "heat shock factor",
            "cell cycle",
            "n terminal"
        ],
        "authors": [
            {
                "name": "J Wu",
                "org": "Lewis Thomas Laboratory, Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014, USA."
            },
            {
                "name": "A Newton",
                "org": "Lewis Thomas Laboratory|Department of Molecular Biology|Princeton University"
            }
        ],
        "venue": "Journal of bacteriology",
        "year": 1996
    },
    "3j9kJQvL": {
        "id": "3j9kJQvL",
        "title": "Optimization hydrolysis processing of glutinous rice wine lees by protease",
        "abstract": "In order to increase amino nitrogen content in the hydrolysate,the hydrolysis processing of glutinous rice wine lees were optimized by acid protease for alcoholic beverage and pawpaw protease,respectively.The hydrolysis experiment results of different protease showed that acid protease for alcoholic beverage was better;The optimal hydrolysis conditions were: protease amount of 2 000 U per 1 g wine lees,solid-liquid ratio of 1∶3,pH3.5,reaction temperature 40℃ and reaction time 5 h.Under these conditions,amino nitrogen content in hydrolyzate achieved to 0.75 g/L,which was increased by 368.75% compared to that of the initial glutinous rice wine lees.",
        "keywords": [
            "amino nitrogen",
            "protease",
            "wine lees",
            "glutinous rice",
            "hydrolysis"
        ],
        "authors": [
            {
                "name": "Liu Dayu",
                "org": "College of Biology Industry,Chengdu University,Chengdu ,China"
            },
            {
                "name": "Zhang Xuefeng",
                "org": "College of Biology Engineering,Sichuan Institute of Science and Technology,Zigong ,China"
            },
            {
                "name": "Xia Bingbing",
                "org": "College of Biology Engineering,Sichuan Institute of Science and Technology,Zigong ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "College of Biology Engineering,Sichuan Institute of Science and Technology,Zigong ,China"
            }
        ],
        "venue": "Cereal & Feed Industry",
        "year": 2011
    },
    "LvcyYwuc": {
        "id": "LvcyYwuc",
        "title": "Genetic analysis of non-essential amino acid contents in rice (Oryza sativa L.) across environments",
        "abstract": "Genetic main effects and genotype × environment (GE) interaction effects for 7 non-essential amino acids in milled rice were analyzed for two year data by using the genetic models based on mixed linear model approaches for quantitative traits of triploid endosperm. Nine cytoplasmic, male sterile lines as females and five restoring lines as males were introduced in a diallel cross in two environments. It was found that the content of non-essential amino acids including Asp, Ser, Glu, Gly and Tyr were mainly controlled by genetic main effects, whereas the content of Ala or Pro was mainly affected by GE effects. In genetic main effects, the cytoplasmic and maternal genetic effects were preponderant for all traits of non-essential amino acids, indicating that selection for improving these traits based on the maternal plant would be more effective than on seeds. The total narrow-sense heritabilities for non-essential amino acids were 70.9-85.9%. By predicating the genetic effects of parents, the total genetic effects from Xieqingzao, V20, Zuo 5 and Zhenshan 97 were mainly negative and these parents would decrease the content of most essential amino acids. Since parents of Zhenan 3, Yinchao 1, T49, 26715, 102 and 1391 had possessed a positive value of most total genetic effects, these parents could be chosen as optimal parents for increasing the content of most non-essential amino acids.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "JIAN GUO WU",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "CHUN HAI SHI",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "XIAO MING ZHANG",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Tomita Katsura",
                "org": "Fukui Agricultural Experiment Station(Fukui Agric. Experiment Station,Fukui Agricultural Experiment Station),Fukui,Japan"
            }
        ],
        "venue": "Hereditas",
        "year": 2004
    },
    "9TpMzIJZ": {
        "id": "9TpMzIJZ",
        "title": "Chemical composition, antimicrobial activity against Staphylococcus aureus and a pro-apoptotic effect in SGC-7901 of the essential oil from Toona sinensis (A. Juss.) Roem. leaves.",
        "abstract": "Leaves of Toona sinensis (A. Juss.) Roem. (TSL), a popular vegetable in China, have anti-inflammatory, antidoting, and worm-killing effects and are used in folk medicine for the treatment of enteritis, dysentery, carbuncles, boils, and especially abdominal tumors. Our aim was to investigate the in vitro antimicrobial activity against Staphylococcus aureus and anticancer property of the essential oil from TSL (TSL-EO), especially the pro-apoptotic effect in SGC-7901.TSL-EO obtained by hydrodistillation was analyzed by GC/MS and was tested in vitro against twenty clinically isolated strains of Staphylococcus aureus (SA 1-20), which were either methicillin-sensitive Staphylococcus aureus (MSSA) or methicillin-resistant Staphylococcus aureus (MRSA) and two standard strains viz. ATCC 25923 and ATCC 43300. The anticancer activity of TSL-EO was evaluated in vitro against HepG2, SGC7901, and HT29 through MTT assay. Moreover, the apoptosis-inducing activity of TSL-EO in SGC7901 cells was determined by Hoechst 33324 staining and flow cytometry methods. Also, the apoptosis-related proteins viz. Bax, Bcl-2 and caspase-3 were detected by western-blotting.GC-MS analysis showed that TSL-EO contained a high amount of sesquiterpenes (84.64%), including copaene (8.27%), β-caryophyllene (10.16%), caryophyllene (13.18%) and β-eudesmene (5.06%). TSL-EO inhibited the growth of both MSSA and MRSA, with the lowest MIC values of 0.125 and 1mg/ml, respectively. Treatment with TSL-EO for 24h could significantly suppress the viability of three different cancer cell lines (P<0.05). Furthermore, the apoptosis-inducing activity of TSL-EO in SGC7901 cells increased in a dose-dependent manner, potentially resulting from the up-regulated expression of Bax, caspase-3 and down-regulated expression of Bcl-2.TSL-EO possessed antibacterial activity against Staphylococcus aureus and significant cytotoxicity against cancer cells and particularly prominent pro-apoptotic activity in SGC7901 cells. These bioactivities were probably due to the high content of sesquiterpenes. Our results suggested that TSL-EO possessed potential health benefits and could serve as a promising natural food addictive.",
        "keywords": [
            "Anti-Staphlococcal activity",
            "Apoptosis",
            "Cytotoxicity",
            "Essential oil",
            "Sesquiterpene",
            "Toona sinensis (A. Juss.) Roem."
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, PR China."
            },
            {
                "name": "Wei Peng",
                "org": "Department of Pharmacology, College of Pharmacy, Third Military Medical University, Chongqing 400038, PR China."
            },
            {
                "name": "Jun Yi",
                "org": "Department of Chemistry and Life Science, Fujian Institute of Education, Fuzhou 350001, PR China."
            },
            {
                "name": "Yan-Bin Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, PR China."
            },
            {
                "name": "Ti-Qiang Chen",
                "org": "Institute of Edible and Medicinal Fungi, Fujian Academy of Agricultural Sciences, Fuzhou 350013, PR China."
            },
            {
                "name": "Ka-Hing Wong",
                "org": "Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, PR China."
            },
            {
                "name": "Jin-Zhong Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, PR China."
            }
        ],
        "venue": "Journal of ethnopharmacology",
        "year": 2014
    },
    "ko79IMCa": {
        "id": "ko79IMCa",
        "title": "Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion.",
        "abstract": "Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays a key role in host innate immune responses by activating caspase-1 to facilitate interleukin-1β (IL-1β) secretion. Here we report that ZIKV stimulates IL-1β secretion in infected patients, human PBMCs and macrophages, mice, and mice BMDCs. The knockdown of NLRP3 in cells and knockout of NLRP3 in mice inhibit ZIKV-mediated IL-1β secretion, indicating an essential role for NLRP3 in ZIKV-induced IL-1β activation. Moreover, ZIKV NS5 protein is required for NLRP3 activation and IL-1β secretion by binding with NLRP3 to facilitate the inflammasome complex assembly. Finally, ZIKV infection in mice activates IL-1β secretion, leading to inflammatory responses in the mice brain, spleen, liver, and kidney. Thus we reveal a mechanism by which ZIKV induces inflammatory responses by facilitating NLRP3 inflammasome complex assembly and IL-1β activation.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenbiao Wang",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, P.R. China."
            },
            {
                "name": "Geng Li",
                "org": "School of Chinese Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, P.R. China."
            },
            {
                "name": "De Wu",
                "org": "Institute of Pathogenic Microbiology, Center for Disease Control and Prevention of Guangdong, Guangzhou, 510006, P.R. China."
            },
            {
                "name": "Zhen Luo",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, P.R. China."
            },
            {
                "name": "Pan Pan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Mingfu Tian",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Yingchong Wang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Feng Xiao",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Aixin Li",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Xiaohong Liu",
                "org": "School of Chinese Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, P.R. China."
            },
            {
                "name": "Lang Rao",
                "org": "School of Physics and Technology, Wuhan University, Wuhan, 430072, P.R. China."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, P.R. China. liufung@whu.edu.cn."
            },
            {
                "name": "Yingle Liu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, P.R. China. mvlwu@whu.edu.cn."
            },
            {
                "name": "Jianguo Wu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, P.R. China. jwu@whu.edu.cn."
            }
        ],
        "venue": "Nature communications",
        "year": 2018
    },
    "1LafHta0": {
        "id": "1LafHta0",
        "title": "Epigallocatechin gallate inhibits macaque SEVI-mediated enhancement of SIV or SHIV infection.",
        "abstract": "Background: Human semen contains a factor that can enhance HIV infection up to 10(5)-fold in cultures. This factor is termed semen-derived enhancer of virus infection (SEVI) and is composed of proteolytic fragments (PAP248-286) from prostatic acid phosphatase in semen. In this study, we examined whether macaque SEVI can facilitate simian immunodeficiency virus (SIV) or chimeric simian/human immunodeficiency virus (SHIV) infection. We also studied the effect of epigallocatechin gallate (EGCG) on macaque SEVI-mediated SIV or SHIV enhancement. Methods: SIV or SHIV was mixed with different concentrations of macaque SEVI in the presence or absence of EGCG. The mixture was added to cultures of TZM-bl cells or macaque PBMCs. The effect of EGCG on macaque SEVI was measured by Congo-red staining assay and thioflavin T (ThT) fluorescence assay and was visualized by a transmission electron microscope. Results: We identified that there is one amino acid difference at the site of 277 between human PAP248-286 and macaque PAP248-286. Macaque SEVI significantly enhanced SIV or SHIV infection of TZM-bl cells and macaque PBMCs. EGCG could block macaque SEVI-mediated enhancement of SIV or SHIV infection. Mechanistically, EGCG could degrade the formation of macaque SEVI amyloid fibrils that facilitates HIV attachment to the target cells. Conclusions: The finding that macaque SEVI could enhance SIV or SHIV infection indicates the possibility to use the macaque SEVI in vivo studies with the macaque models. In addition, future studies are necessary to examine whether EGCG can be used as an effective microbicide for preventing SIV or SHIV mucosal transmission.",
        "keywords": [
            "SEVI",
            "macaque",
            "SIV",
            "SHIV",
            "EGCG",
            "amyloid fibrils"
        ],
        "authors": [
            {
                "name": "Run-Hong Zhou",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Le Guo",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Jin-Biao Liu",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Hang Liu",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Wei Hou",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Tong-Cui Ma",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Xu Wang",
                "org": "Temple Univ, Lewis Katz Sch Med, Dept Pathol & Lab Med, MERB 808B,3500 North Broad St, Philadelphia, PA 19140 USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Li Ye",
                "org": "Guangxi Med Univ, Sch Publ Hlth, Nanning, Peoples R China"
            },
            {
                "name": "Wen-Zhe Ho",
                "org": "Wuhan Univ, Sch Basic Med Sci, State Key Lab Virol, Wuhan, Peoples R China"
            },
            {
                "name": "Jieliang Li",
                "org": "Temple Univ, Lewis Katz Sch Med, Dept Pathol & Lab Med, MERB 808B,3500 North Broad St, Philadelphia, PA 19140 USA"
            }
        ],
        "venue": "JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES",
        "year": 2017
    },
    "Nv3d2QHZ": {
        "id": "Nv3d2QHZ",
        "title": "When to use what: Methods for weighting and aggregating sustainability indicators",
        "abstract": "Abstract   Context  Sustainability indices (SIs) have become increasingly important to sustainability research and practice. However, while the validity of SIs is heavily dependent on how their components are weighted and aggregated, the typology and applicability of the existing weighting and aggregation methods remain poorly understood.    Objectives  To close the knowledge gap regarding when to use which weighting and aggregation methods for constructing SIs, we review the most commonly used methods for weighting and aggregating SIs, discuss their benefits and drawbacks, and suggest a process-oriented approach for choosing appropriate weighting and aggregation methods depending on research objectives.    Methods  Our review synthesis was based on peer-reviewed journal articles, books, and reports by international organizations, governmental agencies, and research institutions. After carefully examining their principles, characteristics, and applications, we selected and classified the frequently used methods for indicator weighting and aggregation.    Results  We systematically discuss the benefits and drawbacks of nine weighting methods and three aggregation methods. We propose a four-step process for choosing the most suitable weighting and aggregation methods based on: research purposes, spatial and temporal scales, and sustainability perspectives.    Conclusions  In this research, we chose the most commonly used methods for weighting and aggregating SIs and analyzed the characteristics, strengths and weaknesses of each method. We found that choosing appropriate weighting and aggregation methods for a specific sustainability assessment project is an extremely important and challenging task. To meet this challenge, we propose a process-oriented approach for properly selecting methods according to the purpose, scale and sustainability concept. This approach can facilitate the proper selection of these methods in sustainability research and practice.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoyu Gan",
                "org": "College of Architecture and Environment, Sichuan University, Chengdu, Sichuan Province, China"
            },
            {
                "name": "Ignacio C. Fernández",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Jie Guo",
                "org": "College of Land Management, Nanjing Agricultural University, Nanjing, Jiangsu Province, China"
            },
            {
                "name": "Maxwell C. Wilson",
                "org": "School of Life Sciences, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Yuan-Yuan Zhao",
                "org": "School of Soil and Water Conservation, Beijing Forestry University, Beijing, China"
            },
            {
                "name": "Bingbing Zhou",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ, USA"
            }
        ],
        "venue": "Ecological Indicators",
        "year": 2017
    },
    "7nfooYst": {
        "id": "7nfooYst",
        "title": "SOX9 represses hepatitis B virus replication through binding to HBV EnhII/Cp and inhibiting the promoter activity.",
        "abstract": "Hepatitis B virus (HBV) infection affects 364 million people worldwide and causes a serious global public health problem. The SRY-related high mobility group-box 9 (SOX9) is a risk of developing cirrhosis in patients with chronic hepatitis B and a cancer stem cell marker. However, the role of SOX9 in HBV replication has not been reported. This study revealed a distinct mechanism underling the regulation of HBV replication mediated by SOX9. HBV induces SOX9 mRNA and protein expression in human hepatoma cells, including HepG2.2.15, HepG2, Huh7, and HepG2-NTCP cells. Further study demonstrated that HBV activates SOX9 expression at the transcriptional level through inducing SOX9 promoter activity and HBc could induce the activity of SOX9 promoter. Interestingly, SOX9 in turn represses HBV replication in human hepatoma cells. More importantly, SOX9 inhibits HBV infection in HepG2-NTCP cells and C57/BL6 mice. Detailed study revealed that SOX9 suppresses HBV replication through directly binding to HBV EnhII/Cp (HBV 1667-1672 nt) to inhibit EnhII/Cp activation. Results from deletion mutant analysis, ChIP assay, nuclear and cytoplasmic extraction analysis, and immunofluorescence demonstrated that SOX9 high mobility group (HMG) domain is required for SOX9 anti-HBV activity. Moreover, we demonstrated that SOX9 and hepatocyte nuclear factor 4 alpha (HNF4α) can bind to HBV EnhII/Cp (HBV 1667-1672 nt) individually and simultaneously to regulate the promoter activity. Collectively, the results revealed a distinct negative feedback mechanism underlying HBV replication and SOX9 expression, and identified SOX9 as a new host restriction factor in HBV replication and infection. IMPORTANCE: HBV infection is a global public health problem by causing serious liver diseases, but the mechanisms underlying HBV pathogenesis remain largely unknown. SOX9 is a risk of developing cirrhosis and a cancer stem cell marker, however, the role of SOX9 in HBV infection has not been reported. The authors revealed a distinct mechanism underling the regulation of HBV replication and SOX9 expression. On one hand, HBV induces SOX9 expression in human hepatoma cells through activating SOX9 promoter. On the other hand, SOX9 in turn represses HBV replication in human hepatoma cells by binding to and inhibiting HBV EnhII/Cp through its HMG domain. More importantly, SOX9 inhibits HBV infection in HepG2-NTCP cells and C57/BL6 mice. Therefore, this study identifies SOX9 as a novel and potential therapeutic reagent for the prevention and treatment of HBV-associated diseases.",
        "keywords": [
            "HBV",
            "HBV EnhII/Cp",
            "HBV core antigen",
            "HBV surface antigen",
            "HBcAg",
            "HBsAg",
            "HNF4α",
            "Hepatitis B virus",
            "Hepatocyte nuclear factor 4 alpha",
            "SOX9",
            "SRY-Related high mobility group-box gene 9"
        ],
        "authors": [
            {
                "name": "Hua Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Yao Zhou",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Jiayin Mo",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Mengying Qin",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Jian Shang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Qingyu Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Wei Xu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Yang Ge",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Quiping Tan",
                "org": "Guangdong Longfan Biological Science and Technology Company, Shunde District, Foshan, 528315, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China. Electronic address: wukailang@whu.edu.cn."
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China; Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China. Electronic address: mvlwu@whu.edu.cn."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China; Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China. Electronic address: jwu@whu.edu.cn."
            }
        ],
        "venue": "Antiviral research",
        "year": 2020
    },
    "W2qPVqRh": {
        "id": "W2qPVqRh",
        "title": "UNCERTAINTY ANALYSIS IN ECOLOGICAL STUDIES:AN OVERVIEW",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "JIANGUO WU",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, 85287-4501 Tempe, AZ USA"
            },
            {
                "name": "HARBIN LI",
                "org": "USDA Forest Service Southern Research Station, Center for Forested Wetlands Research, 29414 Charleston, SC USA"
            }
        ],
        "venue": "",
        "year": 2006
    },
    "vyhDBF0S": {
        "id": "vyhDBF0S",
        "title": "HCV NS2 protein inhibits cell proliferation and induces cell cycle arrest in the S-phase in mammalian cells through down-regulation of cyclin A expression.",
        "abstract": "Chronic hepatitis C virus (HCV) infection often leads to liver cancer. NS2 protein is a HCV hydrophobic transmembrane protein that associates with several cellular proteins in mammalian cells. In this report, we investigated the functions of NS2 protein by examining its effects on cell growth and cell cycle progression. Stable NS2-expressing HeLa and Vero cell lines were established by transfection of the cells with pcDNA3.1(-)-NS2 followed by selection of the transfected cells in the presence of G418. We found that the proliferation rates of both NS2-expressing cell lines were inhibited by 40-50% compared with the control cells that were transfected with pcDNA3.1(-) control vector. Cell cycle analysis of these NS2-expressing cell lines shows that the proportion of cells in the S-phase increased significantly compared to that of control cells that do not express NS2 protein, suggesting NS2 protein induces cell cycle arrest in the S-phase. Further studies showed that the induction of cell cycle arrest in the S-phase by NS2 protein is associated with the decrease of cyclin A level. In contrast, the expression of NS2 protein does not affect the levels of cyclin-dependent kinase CDK2, CDK4, cyclin D1, or cyclin E. Our results suggest that HCV NS2 protein inhibits cell growth and induces the cell cycle arrest in the S-phase through down-regulation of cyclin A expression, which may be beneficial to HCV viral replication. Our findings not only provide information in the understanding mechanism of HCV infection, but also provide guidance for the future development of potential therapeutics for the prevention and treatment of the viral infection.",
        "keywords": [
            "cell cycle arrest",
            "ns2 protein",
            "hcv",
            "growth inhibition",
            "cyclin dependent kinase",
            "cell line",
            "cell cycle",
            "cell proliferation",
            "cell growth",
            "transmembrane protein"
        ],
        "authors": [
            {
                "name": "Xiao-Jun Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Jing Liu",
                "org": "College of Pharmacy, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Li Ye",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Qing-Jiao Liao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Jin-Rong Gao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Ying-Long She",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Zheng-Hui Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China"
            },
            {
                "name": "Lin-Bai Ye",
                "org": ""
            }
        ],
        "venue": "Virus research",
        "year": 2006
    },
    "ReB6G9kU": {
        "id": "ReB6G9kU",
        "title": "Rice grassy stunt virus nonstructural protein p5 serves as a viral suppressor of RNA silencing and interacts with nonstructural protein p3",
        "abstract": "Rice grassy stunt virus (RGSV), a member of the genus Tenuivirus, causes serious rice disease in Southeast Asian countries. In this study, a green fluorescent protein (GFP)-based transient expression assay was conducted to show that p5, encoded on RNA5 in the viral sense, is a viral suppressor of RNA silencing (VSR). Protein-protein interactions (PPIs) between p5 and all RGSV proteins except pC1 and pC2 were investigated using Gal4-based yeast two-hybrid (Y2H) experiments. The results demonstrated that p5 interacts with itself and with p3 encoded on RNA3 in the viral sense. p5-p5 and p5-p3 interactions were detected by bimolecular fluorescence complementation (BiFC) assay, and the p5-p3 interaction was confirmed by subcellular co-localization and co-immunoprecipitation (Co-IP) assays. Using the Y2H system, we demonstrated that the p5-p3 interaction requires both the N-terminal (amino acid residues 1 to 99) and C-terminal (amino acid residues 94 to 191) domains of p5. In addition, either p5 or p3 could enhance the pathogenicity of potato virus X (PVX) in Nicotiana benthamiana plants. A much more significant enhancement of PVX pathogenicity and accumulation was observed when p5 and p3 were expressed together. Our data also showed that RGSV p3 does not function as a VSR, and it had no effect on the VSR activity of p5 or the subcellular localization pattern of p5 in plant cells from Nicotiana benthamiana. ",
        "keywords": [
            "Green Fluorescent Protein",
            " Benthamiana Plant",
            " Rice Stripe Virus",
            " Leaf Epidermal Cell",
            " BiFC Assay"
        ],
        "authors": [
            {
                "name": "chao zhang",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "xiaojuan liu",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "kangcheng wu",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "luping zheng",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "zuomei ding",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "fei li",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "peng zou",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "liang yang",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "jianguo wu",
                "org": "fujian agriculture and forestry university"
            },
            {
                "name": "zujian wu",
                "org": "fujian agriculture and forestry university"
            }
        ],
        "venue": "Archives of Virology",
        "year": 2015
    },
    "uJOPelGc": {
        "id": "uJOPelGc",
        "title": "Simulation design and primary usage of corneal contact lens in rats",
        "abstract": "Objective To develop a rat corneal contact lens basing on simulation design and observe its primary effect for intravitreal injection.Methods The experiment was divided into 2 parts.Part 1:After the ocular physical parameters being measured,an adult SD rat eyeball model was designed by UG software.Then,the corresponding corneal contact lens model was designed by Light Tools software and manufactured.Part 2:Twenty healthy adult SD rats treating intravitreal injection of bone marrow mesenchymal stem cells(BMMSC) were randomly divided into 2 groups,the new corneal contact lens was used in group A(10 rats,10 eyes) and traditional methods of coverslip flattening the cornea in group B(10 rats,10 eyes).The experimental effect,complication and cost time were recorded and compared.All the operations were performed by the same person.Designed corneal contact lens was used in group A,and traditional cover glass was used to press cornea for completing operation in group B.Clear level of fundus image was recorded,the complete time and complications were compared between the two groups.Results The physical parameter of simulation-designed rat eyeball was similar to the results from foreign research works and the plastic contact lens was suit for all animals in this experiment.With the help of the new designed corneal contact lens,the posterior capsule of lens,vitreous and retina in rats were distinct and intravitreal injection was quickly achieved through two-hands assistance,the whole operation time cost(192.50±22.51)s in group A,whereas,the fundus images were not stable and the intravitreous injection was performed by single hand in group B,the operation time consumed(446.90±41.11)s.There was a significant difference(t=-17.17,P<0.01),and the time saved 254.40 s in group A.In additional,no complication occurred in group A,but 2 cases of lens injury occurred in group B,although there was no statistical difference(P=0.273).Conclusions The corneal contact lens designed by UG 7.5 and Light Tools 7.0 simulation software is simple and quickly to observe the fundus image,most importantly,it can realize the two-hands operation and obviously improve the efficiency of animal experiments.",
        "keywords": [
            "intravitreal injection",
            "simulation design",
            "contact lens",
            "rat"
        ],
        "authors": [
            {
                "name": "LI Jun-Ling",
                "org": ""
            },
            {
                "name": "ZHOU Xiao-Xu",
                "org": ""
            },
            {
                "name": "SONG Yan-Ping",
                "org": ""
            },
            {
                "name": "ZHAO Yu-Xin",
                "org": ""
            },
            {
                "name": "LI Na",
                "org": ""
            },
            {
                "name": "WU Jian-Guo",
                "org": ""
            }
        ],
        "venue": "Recent Advances in Ophthalmology",
        "year": 2011
    },
    "wWNChDCE": {
        "id": "wWNChDCE",
        "title": "A GIS-based framework to identify priority areas for urban environmental inequity mitigation and its application in Santiago de Chile",
        "abstract": "Abstract   Environmental inequity is a common phenomenon of modern cities, particularly in the developing world where the high rates of urbanization often surpass the capacity of local governments to develop proper urban planning. In these cities the spatial distribution of environmental quality is frequently associated with socioeconomic characteristics, with vulnerable sectors often having a disproportionately larger share of environmental problems. While reducing environmental inequity is widely recognized as an important step towards more sustainable cities, decision-makers usually lack the tools and information for designing effective and efficient intervention strategies. A challenging decision is to resolve on where, among all the areas having environmental problems, efforts should be allocated first. Here we present a GIS-based framework that can help decision-makers to prioritize the spatial allocation of policy interventions at different spatial scales or administrative levels. The framework focuses on (1) identifying areas having the highest levels of environmental problems, (2) identifying areas having the highest levels of social relevance, and (3) prioritizing the allocation of resources within the areas concurrently having the highest levels of environmental problems and social relevance. To show the potential use of the framework we apply it to the city of Santiago de Chile at three different scales. Our assessment focuses on three main environmental problems currently affecting this city: urban heat, lack of green infrastructure, and air pollution. Based on the results from Santiago, we discuss how the framework can be used to help policy-makers to identify priority areas for policy intervention at their respective administrative level.",
        "keywords": "",
        "authors": [
            {
                "name": "Ignacio C. Fernández",
                "org": "Centro de Estudios de Recursos Naturales OTERRA, Universidad Mayor, Santiago, RM 8340585, Chile"
            },
            {
                "name": "Ignacio C. Fernández",
                "org": "Centro de Estudios de Recursos Naturales OTERRA, Universidad Mayor, Santiago, RM 8340585, Chile"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            }
        ],
        "venue": "Applied Geography",
        "year": 2018
    },
    "hZx1olD3": {
        "id": "hZx1olD3",
        "title": "A New Mode of Industry-Oriented Co-op Education in Higher Vocational Colleges",
        "abstract": "There is a limitation in the traditional education combined with industry,education and scientific research,in which some requirements and benefits of industry were not fully considered,thus such education became a piece of unilateral work in higher vocational colleges and hindered the development of the co-op education.In this paper,the authors analysed some urgent requirements of the industry to the colleges and the advantages of the Higher vocational colleges,a new mode with an industry-oriented “scientific research + two-way training” as an engine in the co-op education is designed,applied and promoted in practice.",
        "keywords": [
            "mutual achievements for both the college and the enterprise",
            "co-op education",
            "“scientific research + two-way traning” mode"
        ],
        "authors": [
            {
                "name": "YI Shun-ming",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "WANG Yan-hui",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2007
    },
    "0NCA7C9r": {
        "id": "0NCA7C9r",
        "title": "A novel recombinant bacterial vaccine strain expressing dual viral antigens induces multiple immune responses to the Gag and gp120 proteins of HIV-1 in immunized mice.",
        "abstract": "Recombinant Salmonella enterica serovar Typhi can function as a live vector to deliver foreign antigens to the mammalian immune system and induce both mucosal and systemic immunity. In this study, we generated a recombinant Salmonella Typhi strain pilS-pilT-Gag+ (pVAX1-gp120) harboring the human immunodeficiency virus (HIV) gag gene integrated into the bacterial chromosome and gp120 gene carried by a plasmid. Mice inoculated with this recombinant bacterium through intranasal route produced high titers of IgG to gp120 in sera and IgA to gp120 in fecal washes. In addition, Gag-specific and gp120-specific cytotoxic T lymphocyte (CTL) responses were observed in sorted spleen lymphocytes of immunized mice. These results demonstrated that this recombinant Salmonella Typhi strain elicits multiple immune responses against both Gag and gp120 antigens of HIV, and thus would be a potential vaccine candidate to the prevention of HIV/AIDS.",
        "keywords": [
            "antibody",
            "aids",
            "vaccine",
            "cytotoxic t lymphocyte response",
            "recombinant salmonella enterica serovar typhi vaccine strain",
            "immune responses",
            "hiv",
            "immune response",
            "cytotoxic t lymphocyte",
            "immune system"
        ],
        "authors": [
            {
                "name": "Yong Feng",
                "org": ""
            },
            {
                "name": "Shiqun Wang",
                "org": ""
            },
            {
                "name": "Fenglin Luo",
                "org": "State Key Laboratory of Virology and College of Medicine, Wuhan University, Wuhan 430071, PR China"
            },
            {
                "name": "Ying Ruan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Lei Kang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Xiaohui Xiang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Tao Chao",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Guiqing Peng",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Chengliang Zhu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wychang, Wuhan 430072, Hubei, PR China"
            },
            {
                "name": "Xiaolian Zhang",
                "org": "State Key Laboratory of Virology and College of Medicine, Wuhan University, Wuhan 430071, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Antiviral research",
        "year": 2008
    },
    "bapTx2hn": {
        "id": "bapTx2hn",
        "title": "The V protein of mumps virus plays a critical role in pathogenesis.",
        "abstract": "Mumps virus (MuV) causes an acute infection in humans characterized by a wide array of symptoms ranging from relatively mild manifestations, such as parotitis, to more-severe complications, such as meningitis and encephalitis. Widespread mumps vaccination has reduced mumps incidence dramatically; however, outbreaks still occur in vaccinated populations. The V protein of MuV, when expressed in cell culture, blocks interferon (IFN) expression and signaling and interleukin-6 (IL-6) signaling. In this work, we generated a recombinant MuV incapable of expressing the V protein (rMuVΔV). The rescued MuV was derived from a clinical wild-type isolate from a recent outbreak in the United States (MuV(Iowa/US/06), G genotype). Analysis of the virus confirmed the roles of V protein in blocking IFN expression and signaling and IL-6 signaling. We also found that the rMuV(Iowa/US/06)ΔV virus induced high levels of IL-6 expression in vitro, suggesting that V plays a role in reducing IL-6 expression. In vivo, the rMuV(Iowa/US/06)ΔV virus was highly attenuated, indicating that the V protein plays an essential role in viral virulence.",
        "keywords": [
            "cell line",
            "flow cytometry"
        ],
        "authors": [
            {
                "name": "Pei Xu",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Priya Luthra",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Zhuo Li",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Sandra Fuentes",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "James Alexander D'Andrea",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Steven Rubin",
                "org": "FDA Center for Biologics Evaluation and Research(Center for Biologics Evaluation and Research,Ctr. for Biologics Eval. and Res.),Bethesda,United States"
            },
            {
                "name": "Paul A Rota",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            },
            {
                "name": "Biao He",
                "org": "The University of Georgia(University of Georgia),Athens,United States"
            }
        ],
        "venue": "Journal of virology",
        "year": 2012
    },
    "O3cERh1X": {
        "id": "O3cERh1X",
        "title": "Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.",
        "abstract": "This paper aimed to elucidate the anti-inflammatory effects of EtOAc fraction prepared from Melilotus suaveolens Ledeb ethanol extract with a cellular model of LPS-stimulated RAW 264.7 cell.Some key pro-inflammatory cytokines and mediators including IL-1 beta, IL-6, NO, iNOS, COX-2 and TNF-alpha, two important anti-inflammatory cytokines and mediators IL-10 and HO-1, I-kappaB and NF-kappaB were studied by sandwich ELISA, real-time PCR, western blot analysis and immunocytochemistry. At last a HPLC fingerprint was taken to evaluate the fraction.The EtOAc fraction could significantly inhibit the production of IL-1 beta, IL-6, NO, TNF-alpha, COX-2 in LPS-stimulated cell than that of single LPS-stimulated cell (p<0.01 or p<0.05), and the extract could increase the production of IL-10 and HO-1 than that of single LPS intervention cell (p<0.01 or p<0.05). Meanwhile, the extract also could inhibit the production of NF-kappaB compared to single LPS-stimulated cell. All the results showed that the extract had a good anti-inflammatory effect on LPS-stimulated RAW264.7 cell.Taken together, the anti-inflammatory actions of M. suaveolens Ledeb EtOAc fraction might be due to the down-regulation of IL-1 beta, IL-6, NO, TNF-alpha and COX-2 via the suppression of NF-kappaB activation, and another pathway was up regulating the production of IL-10 and HO-1. Meanwhile, the EtOAc fraction might be further studied to isolate the active anti-inflammatory ingredients besides coumarin.",
        "keywords": [
            "hplc fingerprint",
            "melilotus suaveolens ledeb etoac fraction",
            "anti-inflammatory cytokines and mediators",
            "pro-inflammatory cytokines and mediators",
            "raw 264.7 cell",
            "cellular model",
            "interleukin 6",
            "extracts",
            "ethanol",
            "traditional medicine",
            "interleukins",
            "polymerase chain reaction",
            "interleukin 10",
            "pharmacology",
            "production",
            "immunocytochemistry"
        ],
        "authors": [
            {
                "name": "Jun-Yan Tao",
                "org": ""
            },
            {
                "name": "Guo-Hua Zheng",
                "org": ""
            },
            {
                "name": "Lei Zhao",
                "org": "Department of Hepatology & Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Xiao-Yu Zhang",
                "org": ""
            },
            {
                "name": "Shu-Ling Zhang",
                "org": "Department of Hepatology & Infectious Disease, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, PR China"
            },
            {
                "name": "Zhi-Jun Huang",
                "org": "Hubei & Wuhan Engineering Technology Center of Modernization Traditional Chinese Medicine, Wuhan Jianmin Pharmacy of TCM Co., Ltd., Wuhan, 430054, PR China"
            },
            {
                "name": "Fu-Liang Xiong",
                "org": "Hubei & Wuhan Engineering Technology Center of Modernization Traditional Chinese Medicine, Wuhan Jianmin Pharmacy of TCM Co., Ltd., Wuhan, 430054, PR China"
            },
            {
                "name": "Chong-Ming Li",
                "org": "Hubei & Wuhan Engineering Technology Center of Modernization Traditional Chinese Medicine, Wuhan Jianmin Pharmacy of TCM Co., Ltd., Wuhan, 430054, PR China"
            }
        ],
        "venue": "Journal of ethnopharmacology",
        "year": 2009
    },
    "c3suT2vX": {
        "id": "c3suT2vX",
        "title": "Net primary productivity of Leymus chinensis steppe in Xilin River basin of Inner Mongolia and its responses to global climate change",
        "abstract": "CENTURY model was utilized to simulate the annual aboveground net primary production (ANPP) of Leymus chinensis steppe, a dominant community type in Xilin River basin of Inner Mongolia steppe region. The results showed that the model performed reasonably well in predicting the dynamics of the ANPP. The scenario-based simulations indicated that though the variations of air temperature and precipitation due to global climate change as well as the elevated CO2 would significantly affect the dynamics of the ANPP, precipitation was the key affecting factor. Several GCM models had predicted that the precipitation in this region would decrease in the future, and consequently, it was likely that the ANPP would also decrease. Nevertheless, the simulation results showed that while the ANPP decreased in most climate change scenarios, it might also increase in the following climate change scenarios: 1) if the atmospheric CO2 concentration was doubled, air temperature was increased by 2 degrees C, and precipitation was kept unchanged or increased by 10%-20%, and 2) if the atmospheric CO2 concentration was kept unchanged, air temperature was increased by 2 degrees C, and precipitation was increased by 20%. Overall, it was evident that climate change would have significant effects on the steppe in Xilin River basin of Inner Mongolia.",
        "keywords": [
            "ANPP",
            "CENTURY model",
            "Climate change",
            "Leymus chinensis steppe"
        ],
        "authors": [
            {
                "name": "Fei Yuan",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Xing-Guo Han",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jian-Ping Ge",
                "org": "Beijing Normal University(Beijing Normal University),Beijing,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            }
        ],
        "venue": "Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban",
        "year": 2008
    },
    "68T8Swoz": {
        "id": "68T8Swoz",
        "title": "Simultaneously inhibition of HIV and HBV replication through a dual small interfering RNA expression system.",
        "abstract": "Human immunodeficiency virus (HIV) is often acquired in individuals already infected with hepatitis B virus (HBV) as a result of shared routes of transmission. Since current options for the treatment of HIV and HBV infections are limited, there is an essential need for the development of effective therapies against HIV/HBV co-infections. RNA interference (RNAi) has been used as a powerful tool to silence genes in cells and animals. In this study, we developed a small interfering RNA generation system that expressed two different siRNAs to target the HBs gene of HBV and the gp120 gene of HIV in Bel-7402 and HEK293T cells, respectively. Our results demonstrated that the two siRNA molecules could simultaneously inhibit the expression of HBs and gp120 by 81% and 89%, respectively. In addition, dual siRNA molecules significantly decreased the production of HBs, and simultaneously inhibited the replication of HBV and HIV. This dual siRNA generation system not only proved to be a novel approach for studying functions of multiple genes simultaneously, but also provides a potential approach for the treatment and prevention of HIV and HBV co-infection.",
        "keywords": [
            "viral replication",
            "dual sirna",
            "hbv",
            "hiv",
            "small interfering rna",
            "rna interference"
        ],
        "authors": [
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jing Hu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Lu Lu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Xue Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yongbo Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yan Li",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Degui Song",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Antiviral research",
        "year": 2007
    },
    "GAM6CwQq": {
        "id": "GAM6CwQq",
        "title": "Handwritten Digit Recognition Based on Image Recognition System",
        "abstract": "As the world economy is more developed,countries deepening economic exchanges,people has to deal with a lot of notes each day.Handwritten digits in this field is necessary,for example,to deal with a lot of people check,invoice,goods such as single data,which have a lot to deal with data.The traditional method is to use the optical principle of the photoelectric conversion to identify digit,it is relatively high for environmental requirements,high cost,low recognition rate and real-time.In this paper,handwritten numeral recognition technology from 0 to 9 is proposed based on image recognition.Experiments show that accurately identify 2,3,4,5,8,9 characters,while the 1,7,0,6,basic identification number is correct,this method improves the recognition rate of digital and real-time.",
        "keywords": [
            "digital identification",
            "image recognition",
            "handwritten numerals"
        ],
        "authors": [
            {
                "name": "WU Zhong",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHU Guo-long",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "HUANG Ge-feng",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2011
    },
    "AAvclAQa": {
        "id": "AAvclAQa",
        "title": "How do travel distance and park size influence urban park visits",
        "abstract": "Abstract   Urban parks are of great importance for residents’ health and well-being. As two main factors influencing park visit, distance to park and park size have been studied and adopted in practice such as park planning and guidelines. This study aims to examine how travel distance and park size associated with park visits and how these effects may vary across different types of park visits in Beijing, China. We conducted a city-wide survey in 78 neighborhoods, and interviewed 7,362 residents on their park visit behaviors. Constraint line analysis, Pearson correlation analysis, and significant differences analysis were employed. We found that travel distance had an exponential limiting effect on park visit. The maximum park visits dropped exponentially as the travel distance to parks increased. No such effect was observed for park size. Visitors to nearby, medium-distance, and distant parks varied significantly in terms of park visit frequency, travel mode, time spent in park, and activity. Their destination parks also differed in size, vegetation cover and whether water area is present. Furthermore, we identified four cut-off points (1, 2, 5, and 10 km) based on the constraint line functions as the accessible and maximum travel distance regarding different travel modes and visit frequencies of park visits. Our findings provided empirical evidence on the association among travel distance, park size and visit, which have important implications for future park studies and planning.",
        "keywords": "",
        "authors": [
            {
                "name": "Xingyue Tu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Ganlin Huang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Xuan Guo",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            }
        ],
        "venue": "Urban Forestry & Urban Greening",
        "year": 2020
    },
    "HyEJ35aK": {
        "id": "HyEJ35aK",
        "title": "Developmental genetic analysis of milled rice weight at different filling stages in Indica rice (Oryza sativa L.)",
        "abstract": "Analysis of developmental genetic effects for milled rice weight (MRW) trait in indica rice (Oryza sativa L.) at four different filling stages of rice was conducted by using developmental genetic models and corresponding statistical approaches for quantitative traits of triploid endosperm in cereal models and corresponding statistical approaches for quantitative traits of triploid endosperm in cereal crops. It was indicated that the triploid endosperm, cytoplasmic and diploid maternal plant genetic effects were important for MRW traits at different filling stages of rice, especially for maternal additive and dominance effects. Because of the higher endosperm and maternal additive effects for MRW, the better improving effects for this trait could be expected by selection in rice breeding. The results of conditional genetic variance components showed that the new expression of quantitative genes in endosperm, cytoplasm and maternal plant for MRW was mostly found at all different filling stages of rice. The gene expression, however, was most active at the early filling stages especially for the second stage (8-14 d after flowering). The phenomena which some genes were spasmodically expressible among filling stages of rice were detected for some genetic effects especially for cytoplasmic effects. Predicted genetic effects and conditional genetic effects at different filling stages of rice showed that some parents such as Zuo 5 were better than others for improving the MRW trait.",
        "keywords": [
            "Developmental genetics",
            "Genetic effects",
            "Genetic variances and conditional genetic variances",
            "Indica rice (Oryza sativa L.)",
            "Milled rice weight"
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jun Zhu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "LongJiang Fan",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ping Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of the Zhejiang University - Agriculture and Life Science",
        "year": 2001
    },
    "L93Jq1ea": {
        "id": "L93Jq1ea",
        "title": "Ecosystem stability and compensatory effects in the Inner Mongolia grassland.",
        "abstract": "Numerous studies have suggested that biodiversity reduces variability in ecosystem productivity through compensatory effects; that is, a species increases in its abundance in response to the reduction of another in a fluctuating environment. But this view has been challenged on several grounds. Because most studies have been based on artificially constructed grasslands with short duration, long-term studies of natural ecosystems are needed. On the basis of a 24-year study of the Inner Mongolia grassland, here we present three key findings. First, that January-July precipitation is the primary climatic factor causing fluctuations in community biomass production; second, that ecosystem stability (conversely related to variability in community biomass production) increases progressively along the hierarchy of organizational levels (that is, from species to functional group to whole community); and finally, that the community-level stability seems to arise from compensatory interactions among major components at both species and functional group levels. From a hierarchical perspective, our results corroborate some previous findings of compensatory effects. Undisturbed mature steppe ecosystems seem to culminate with high biodiversity, productivity and ecosystem stability concurrently. Because these relationships are correlational, further studies are necessary to verify the causation among these factors. Our study provides new insights for better management and restoration of the rapidly degrading Inner Mongolia grassland.",
        "keywords": [
            "nanotechnology",
            "biochemistry",
            "neuroscience",
            "genomics",
            "cell cycle",
            "biology",
            "pharmacology",
            "genetics",
            "neurobiology",
            "marine biology",
            "functional genomics",
            "evolutionary biology",
            "medical research",
            "signal transduction",
            "developmental biology",
            "geophysics",
            "computational biology",
            "rna",
            "environmental science",
            "ecosystem stability",
            "nature",
            "bioinformatics",
            "quantum physics",
            "cancer",
            "transcriptomics",
            "medicine",
            "cell signalling",
            "systems biology",
            "immunology",
            "astrophysics",
            "drug discovery",
            "proteomics",
            "structural biology",
            "astronomy",
            "climate change",
            "dna",
            "ecology",
            "physics",
            "earth science",
            "materials science",
            "molecular biology",
            "biotechnology",
            "evolution",
            "metabolomics",
            "palaeobiology"
        ],
        "authors": [
            {
                "name": "Yongfei Bai",
                "org": "Laboratory of Quantitative Vegetation Ecology, Institute of Botany, Chinese"
            },
            {
                "name": "Xingguo Han",
                "org": "Laboratory of Quantitative Vegetation Ecology, Institute of Botany, Chinese"
            },
            {
                "name": "Jianguo Wu",
                "org": "Faculty of Ecology, Evolution and Environmental Science, School of Life Sciences, Arizona State University, Tempe, Arizona 85287-4501, USA"
            },
            {
                "name": "Zuozhong Chen",
                "org": "Laboratory of Quantitative Vegetation Ecology, Institute of Botany, Chinese"
            },
            {
                "name": "Linghao Li",
                "org": "Laboratory of Quantitative Vegetation Ecology, Institute of Botany, Chinese"
            }
        ],
        "venue": "Nature",
        "year": 2004
    },
    "Rfjh70vR": {
        "id": "Rfjh70vR",
        "title": "Soil-Air Partition Coefficients of Persistent Organic Pollutants Decline from Climate Warming: a Case Study in Yantai County, Shandong Province, China",
        "abstract": "Recognizing the kinetics of the soil-air partition coefficients (Ksoil-air) of persistent organic pollutants (POPs) under distinct scenarios of changing climate conditions is crucial for well understanding the response of POPs exchange process across the air-soil interface to climate warming. Taking Yantai County, Shandong Province, China, as a case study, the Ksoil-air values of HCH, DDE, DDD, and DDT in cropland soil under two levels of soil organic matter (SOM) (0.5% and 1.7%) were projected under future climate scenarios by employing representative concentration pathway (RCP) climate scenarios and a multiple linear model of the Ksoil-air of POPs. Compared to baseline conditions, future climate conditions would shift substantially, and daily Ksoil-air values of HCH, DDE, DDD, and DDT under future climate scenarios would decline by approximately 23–91 (× 105), 5,542–21,703 (× 105), 78–309 (× 105), and 18,986–74,133 (× 105), respectively, under future climate scenarios than under baseline conditions when the SOM content was 0.5% or by approximately 9,167–360,45 (× 105), 128,533–508,592 (× 105), 31,513–123,038 (× 105), and 444,513–1738,367 (× 105), respectively, when the SOM level was 1.7%, or by approximately 2–13% under two levels of SOM. Annual Ksoil-air values of HCH, DDE, DDD, and DDT would decline by approximately 3.51–7.54 (× 105), 842.06–1,806.46 (× 105), 11.83–25.66 (× 105), and 2,840.13–6,153.16 (× 105), respectively, when the SOM content was 0.5%, or by approximately 1,397.47–2,997.98 (× 105), 19,739.82–42,347.56 (× 105), 4,713.44–10,211.70 (× 105), and 66,579.06–144,244.10 (× 105), respectively, when the SOM content was 1.7%, or by approximately 8–18% under two levels of SOM. Moreover, Ksoil-air showed daily, monthly, and seasonal temporal changes within whole years and high temporal yearly fluctuation. Daily and annual Ksoil-air values were lower under 0.5% SOM content than under 1.7% SOM content. The results suggested that the adsorbing capacity of soil to POPs would decrease, and many more POPs in the soil would volatilize to the atmosphere from climate warming.",
        "keywords": [
            "Climate change",
            " Soil-air partition coefficient",
            " Persistent organic pollutants"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "The Institute of Environmental Ecology, Chinese Research Academy of Environmental Sciences, Beijing, China"
            }
        ],
        "venue": "Water, Air, & Soil Pollution",
        "year": 2020
    },
    "qqeEzCky": {
        "id": "qqeEzCky",
        "title": "Research and Application of Catalase on Textile Industry",
        "abstract": "Mechanism of catalase was described.The research status quo of the applications of catalase in biological deoxygenation and oxygen bleaching wastewater treatment in the textile industry were analyzed.",
        "keywords": [
            "catalase",
            "research status quo",
            "textile"
        ],
        "authors": [
            {
                "name": "Wang Lan",
                "org": "Yancheng College of Textile Technology,Yancheng ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "Yancheng College of Textile Technology,Yancheng ,China"
            }
        ],
        "venue": "Shandong Textile Science & Technology",
        "year": 2013
    },
    "tQAFNaIK": {
        "id": "tQAFNaIK",
        "title": "BIAS REDUCTION METHODS FOR THE CONDITIONAL EXTREMA OF SAMPLE FUNCTIONS",
        "abstract": "The order of bias term in the conditional extrema of sample functions is analyzed and some methods for bias reduction are discussed in this paper.It comes to a conclusion that it is not enough for bias reduction while using the classical jackknife or delete-d jackknife method.On the basis of that,a bootstrapping method for bias reduction is mentioned and it is proven thatθ_(nab)is a better estimator in the sense of mse.",
        "keywords": [
            "asymptotic bias",
            "jackknifing",
            "Extrema of sample functions",
            "bootstrapping"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Department of Mathematics,Hunan College of Finance and Economics,Changsha "
            }
        ],
        "venue": "Journal of Systems Science and Mathematical Sciences",
        "year": 2007
    },
    "DVGjXWIS": {
        "id": "DVGjXWIS",
        "title": "Isolation of virus from a SARS patient and genome-wide analysis of genetic mutations related to pathogenesis and epidemiology from 47 SARS-CoV isolates.",
        "abstract": "Severe acute respiratory syndrome (SARS) caused by SARS-associated coronavirus (SARS-CoV) is a fatal disease. Prevention of future outbreaks is essential and requires understanding pathogenesis and evolution of the virus. We have isolated a SARS-CoV in China and analyzed 47 SARS-CoV genomes with the aims to reveal the evolution trends of the virus and provide insights into understanding pathogenesis and SARS epidemic. Specimen from a SARS patient was inoculated into cell culture. The presence of SARS-CoV was determined by RT-PCR and confirmed by electron microscopy. Virus was isolated followed by the determination of its genome sequences, which were then analyzed by comparing with other 46 SARS-CoV genomes. Genetic mutations with potential implications to pathogenesis and the epidemic were characterized. This viral genome consists of 29,728 nucleotides with overall organization in agreement with that of published isolates. A total of 348 positions were mutated on 47 viral genomes. Among them 22 had mutations in more than three genomes. Hot spots of nucleotide variations and unique trends of mutations were identified on the viral genomes. Mutation rates were different from gene to gene and were correlated well with periodical or geographic characteristics of the epidemic.",
        "keywords": [
            "SARS-CoV",
            "isolation",
            "genomic analysis",
            "mutation"
        ],
        "authors": [
            {
                "name": "Ying Zhu",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Mo Liu",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Weiguang Zhao",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Jianlin Zhang",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Xue Zhang",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Ke Wang",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Chunfang Gu",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Kailang Wu",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Yan Li",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Congyi Zheng",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Gengfu Xiao",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Huimin Yan",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Jiamin Zhang",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Deyin Guo",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Po Tien",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Virology, Ministry of Education College of Life Sciences Wuhan University Wuhan 430072 China"
            }
        ],
        "venue": "Virus genes",
        "year": 2005
    },
    "UhsXTMae": {
        "id": "UhsXTMae",
        "title": "ANALYSIS METHOD STUDY OF SWEET POTATO RESIDUE DIETARY FIBER BY FERMENTATION USING IMPROVED ENZYMATIC-GRAVIMETRIC METHOD",
        "abstract": "An improved enzymatic-gravimetric method of fermented dietary fiber by sweet potato residue is introduced in this study.The main points are as follows:1) use scale test tube with stopper as enzymatic reaction container;2) sample needs to be treated by microwave for 1 min before enzymatic reaction;3) glass wool is used for accelerating filtration.Exactitude and recovery of improved enzymatic-gravimetric method are below 6 % and close to 100 % respectively.The accuracy and rapidity of improved enzymatic-gravimetric method for determining fermented dietary fiber by sweet potato residue are also proved.",
        "keywords": [
            "improved enzymatic-gravimetric method",
            "dietary fiber",
            "fermentation"
        ],
        "authors": [
            {
                "name": "LIU Ping",
                "org": "College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan , Hubei, China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan , Hubei, China"
            },
            {
                "name": "GAO Shi",
                "org": "College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan , Hubei, China"
            },
            {
                "name": "LI Yun",
                "org": "College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan , Hubei, China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan , Hubei, China"
            }
        ],
        "venue": "Food Research and Development",
        "year": 2009
    },
    "1ugarLFm": {
        "id": "1ugarLFm",
        "title": "The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene.",
        "abstract": "Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer deaths globally. Chronic hepatitis B virus (HBV) infection accounts for over 75% of all HCC cases; however, the molecular pathogenesis of HCC is not well understood. In this study, we found that the expression of the newly identified gene melanoma inhibitory activity 2 (MIA2) was reduced by HBV infection in vitro and in vivo, and that HBV X protein (HBx) plays a major role in this regulation. Recent studies have revealed that MIA2 is a potential tumor suppressor, and that, in most HCCs, MIA2 expression is down-regulated or lost. We found that the knock-down of MIA2 in HepG2 cells activated cell growth and proliferation, suggesting that MIA2 inhibits HCC cell growth and proliferation. In addition, the over-expression of HBx alone induced cell proliferation, whereas MIA2 over-expression impaired the HBx-mediated induction of proliferation. Taken together, our results suggest that HBx activates hepatoma cell growth and proliferation through repression of the potential tumor suppressor MIA2.",
        "keywords": [
            "cell proliferation",
            "cell growth",
            "hbx",
            "melanoma inhibitory activity 2 gene",
            "hepatitis b virus"
        ],
        "authors": [
            {
                "name": "Yilin Xu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yang Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanyan Cai",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fang Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Biochemical and biophysical research communications",
        "year": 2011
    },
    "K9El8DF3": {
        "id": "K9El8DF3",
        "title": "Epigenetic changes mediated by microRNA miR29 activate cyclooxygenase 2 and lambda-1 interferon production during viral infection.",
        "abstract": "Lambda-1 interferon (IFN-λ1) and cyclooxygenase-2 (COX-2) were reported to play an important role in host antiviral defense. However, the mechanism by which IFN-λ1 and COX2 are activated and modulated during viral infection remains unclear. In this study, we found that expression of both circulating IFN-λ1 and COX2-derived prostaglandin E2 (PGE2) was coordinately elevated in a cohort of influenza patients compared to healthy individuals. Expression of IFN-λ1 was blocked by a selective COX2 inhibitor during influenza A virus infection in A549 human lung epithelial cells but enhanced by overexpression of COX2, indicating that the production of IFN-λ1 is COX2 dependent. COX2 was able to increase IFN-λ1 expression by promoting NF-κB binding to the enhancer in the IFN-λ1 promoter. We found that epigenetic changes activate COX2 expression and PGE2 accumulation during viral infection. The expression of DNA methyltransferase 3a (DNMT3a) and DNMT3b, but not that of DNMT1, was downregulated following influenza A virus infection in both A549 cells and peripheral blood mononuclear cells (PBMCs). We showed that microRNA miR29 suppresses DNMT activity and thus induces expression of COX2 and PGE2. Furthermore, miR29 expression was elevated 50-fold in virally infected A549 cells and 10-fold in PBMCs from influenza patients, compared to expression after mock infection of A549 cells or in healthy individuals, respectively. Activation of the protein kinase A signaling pathway and phosphorylation of CREB1 also contributed to COX2 expression. Collectively, our work defines a novel proinflammatory cascade in the control of influenza A virus infection.",
        "keywords": [
            "chick embryo",
            "micrornas",
            "cell line",
            "young adult",
            "cohort studies",
            "interleukins"
        ],
        "authors": [
            {
                "name": "Jiali Fang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qian Hao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Li Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yongkui Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xixiang Huo",
                "org": "Hubei Provincial Center for Disease Control and Prevention(Hubei Provincial Center for Disease Control and Prevention),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of virology",
        "year": 2012
    },
    "m9NK01S4": {
        "id": "m9NK01S4",
        "title": "Urban sustainability: an inevitable goal of landscape research",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2010
    },
    "soE30N5d": {
        "id": "soE30N5d",
        "title": "Bromodomain containing protein represses the ras/raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.",
        "abstract": "Hepatitis C virus (HCV) infection facilitates the development of hepatocellular carcinoma (HCC). Activation of Ras/Raf/MEK/ERK pathway is found in more than 30% human cancers. Here, we revealed a novel mechanism underlying the regulation of hepatoma cell proliferation mediated by HCV. On one hand, hepatoma cell proliferation is facilitated by HCV infection through a positive feedback regulatory cycle. HCV promotes hepatoma cell proliferation by activating the Ras/Raf/MEK/ERK pathway, which in turn facilitates HCV replication to further enhance hepatoma cell proliferation. On the other hand, hepatoma cell proliferation is attenuated by the bromodomain containing 7 (BRD7), a tumor suppressor, through a negative feedback regulatory mechanism. After activation, the Ras/Raf/MEK/ERK pathway stimulates BRD7 production, which in turn represses the Ras/Raf/MEK/ERK pathway, leading to the attenuation of hepatoma cell proliferation. However, HCV persistent infection attenuates BRD7 gene expression and facilitates the protein degradation to release the Ras/Raf/MEK/ERK signaling, which results in the facilitation of hepatoma cell proliferation. Therefore, we proposed that the balance between BRD7 function and Ras/Raf/MEK/ERK activity is important for determining the outcomes of HCV infection and HCC development.",
        "keywords": [
            "Hepatocellular carcinoma",
            "gene regulation",
            "hepatocarcinogenesis",
            "human hepatoma cell growth",
            "signaling pathway"
        ],
        "authors": [
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Liang Wei",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Hongchuan Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wanqi Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Qingyu Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Zhuofan Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China."
            }
        ],
        "venue": "Cancer letters",
        "year": 2015
    },
    "2g4dvaJ6": {
        "id": "2g4dvaJ6",
        "title": "Value of dynamic subtraction technique of magnetic resonance imaging in preoperative TNM-staging assessment of gastric carcinoma]",
        "abstract": "To explore the value of dynamic subtraction technique of magnetic resonance imaging MRI in preoperative TNM-staging assessment of gastric carcinoma.MRI was performed in 39 patients with gastric carcinoma diagnosed by postoperative pathology.The results of MRI were prospectively analyzed by one professor and compared with the corresponding pathological findings.In comparison with pathological results, the accuracy of MRI for T stage was 82.1%, for N stage was 71.8%, and for M stage was 84.6% respectively. The accuracy of MRI for TNM stage was 71.8%, which revealed concordance between the preoperative TNM-staging and postoperative pathological findings (Kappa= 0.671-0.763, P<0.05).MRI plays an important role in the assessment of invasion depth of gastric carcinoma, lymph node and distant organ metastases,which has unique priority in preoperative TNM-staging assessment of gastric carcinoma.",
        "keywords": [],
        "authors": [
            {
                "name": "Jian-guo Wu",
                "org": "Department of General Surgery, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China."
            },
            {
                "name": "Guo-en Fang",
                "org": ""
            },
            {
                "name": "Tian-hang Luo",
                "org": ""
            },
            {
                "name": "Feng Zhang",
                "org": ""
            }
        ],
        "venue": "Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery",
        "year": 2008
    },
    "YZX7eXzK": {
        "id": "YZX7eXzK",
        "title": "3D-OCT Direct View Method Enhances the Efficiency of Experimental Choroidal Neovascular Model",
        "abstract": "Objective To establish a laser induced choroidal neovascularization(CNV) model by 3D-optical coherence tomography(3D-OCT direct view in chinchilla rabbit. Methods Twenty chinchilla rabbits were randomly divided into 2 groups and right eyes of the rabbits were selected for CNV models: group A(10 rabbits,10 eyes,non-OCT direct view method) and group B(10 rabbits,10 eyes,OCT direct view method).The ocular fundus near to the optic disk 2PD in group A was administrated by krypton laser-coagulation 10 spots until bubbles or minimal hemorrhage emerged.Those in group B received a simultaneous OCT direct view to judge whether Bruch membrane had been disrupted besides all the operations in group A.Twenty-one days later,experimental eyes were examined with ocular fundus photo,OCT and angiography,histological changes also were examined. Results After 21 days,we found that retinal edema vanished,gray splash appeared and yellowish-white exudate emerged around the hemorrhage on the site of laser-coagulation,furthermore,we saw the fluorescein leakaging around laser-coagulation spots.There were 64 spots appeared Bruch's membrane rupture and of which 45 spots appeared CNV in group A vs 100 spots and 86 spots respectively in group B.There was significant statistical difference by chi-square test(P<0.01) and there had positive correlation between Bruch's membrane rupture and CNV incidence. Conclusions Bruch's membrane rupture is the key of inducing CNV model.OCT direct view method can be used as an objective standard to enhance the efficiency of experimental CNV model.",
        "keywords": [
            "Choroidal neovascularization",
            "Laser",
            "Optical coherence tomography"
        ],
        "authors": [
            {
                "name": "SONG Yan-Ping",
                "org": "Department of Ophthalmology of PLA,Wuhan General Hospital,Wuhan ,China"
            },
            {
                "name": "ZHOU Xiao-Xu",
                "org": "Eye Center,Tianjin Medical University"
            },
            {
                "name": "ZHAO Yu-Xin",
                "org": "Department of Ophthalmology of PLA,Wuhan General Hospital,Wuhan ,China"
            },
            {
                "name": "ZHOU He-Zheng",
                "org": "Department of Ophthalmology of PLA,Wuhan General Hospital,Wuhan ,China"
            },
            {
                "name": "WU Jian-Guo",
                "org": "Department of Ophthalmology of PLA,Wuhan General Hospital,Wuhan ,China;Eye Center,Tianjin Medical University"
            }
        ],
        "venue": "Chinese Journal of Laser Medicine & Surgery",
        "year": 2011
    },
    "CtEiDYSN": {
        "id": "CtEiDYSN",
        "title": "Multiscale analysis of the urbanization pattern of the Phoenix metropolitan landscape of USA: Time, space and thematic resolution",
        "abstract": "Investigating the ecological consequences of urbanization require knowledge of land-cover dynam- ics. Quantification of land-use/land-cover change in Phoenix, Arizona during the period of 1985-2005 using landscape metrics computed from Landsat-derived maps revealed temporal patterns of landscape composition and configuration. With accelerated urbanization the landscape as a whole became more fragmented ecologically and more complex compositionally and geometrically. However, the majority of individual patches became more compact in shape. Urban land covers, especially xeric residential, increased substantially and the desert decreased by 20%. Spatial and thematic resolution of data was shown to have large effects on the analysis of land-cover pattern. Our results, while agreeing in general with previously reported scaling relations with respect to changing spatial grain and extent, showed that scaling relations are also robust and consistent across thematic resolutions and time periods. Some metrics behaved unpredictably and some exhibited scale-free behavior. Compositional metrics, such as patch density, diversity, evenness, and largest patch index, were well correlated with vegetative cover, its spatial variation, and population density. Many of these correlations exhibited hump-shaped patterns with respect to increasing grain size, indicating a characteristic scale at approximately 500-1000 m. By simultaneously manipulating spatial and thematic resolutions, the importance of the Modifiable Area Unit Problem in relating landscape patterns to vegetation and socio-economic variables was also demonstrated. Additionally, highly variable desert vegetation due to precipitation variability poses a challenge for accurately quantifying urbanization pattern in arid environments. Choosing appropriate",
        "keywords": [
            "urbanization landscape pattern analysis landscape metrics scale",
            "indexation",
            "spatial variation",
            "grain size",
            "scale free",
            "scale",
            "urbanization",
            "population density"
        ],
        "authors": [
            {
                "name": "Alexander Buyantuyev",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Corinna Gries",
                "org": ""
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2010
    },
    "6HEdb2d2": {
        "id": "6HEdb2d2",
        "title": "Genetic analysis of embryo, cytoplasmic, and maternal effects and their environment interactions for protein content in Brassica napus L.",
        "abstract": "A genetic model for quantitative traits of seeds in diploid plants was applied to estimate the genetic main effects and genotype x environment (GE) interaction effects for protein content (PC) of rapeseed (Brassica napus L.) by using 2 years of experimental data with a diallel mating design of 8 parents. Results showed that PC of rapeseed was simultaneously controlled by genetic effects of embryo, cytoplasm, and maternal plant, of which the maternal genetic effects were most important, followed by embryo and cytoplasmic genetic effects. Therefore, improvement of PC of rapeseed would be more efficient when selection is based on maternal plants than that on single seeds. Since the GE interaction effects accounted for about 60.10% of total genetic effect, they were more important than the genetic main effects, and selection for PC might be influenced by environmental conditions. The total narrow-sense heritability for PC was 64.17%, of which the interaction heritability was larger than the general heritability. Selection for improving PC can therefore be conducted in early generations. Maternal heritability (41.59%) was most important for PC, followed by cytoplasmic heritability (17.62%) and then by embryo heritability (5.25%). Based on prediction of genetic effects, parent Youcai 601 was better than others for increasing PC in rapeseed breeding. © CSIRO 2005.",
        "keywords": [
            "genetic effect",
            "genetic variance",
            "heritability",
            "protein content",
            "rapeseed (brassica napus l.)",
            "embryos",
            "maternal effect",
            "animal nutrition",
            "plant protection",
            "climate",
            "plant breeding",
            "sustainable",
            "agronomy",
            "educational",
            "plant pathology",
            "crop",
            "animal breeding",
            "interaction",
            "water use"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "HaiZhen Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Australian Journal of Agricultural Research",
        "year": 2005
    },
    "dy4tDBTr": {
        "id": "dy4tDBTr",
        "title": "Research of Input Method for Intelligent Mobile Phone on Windows Mobile Platform",
        "abstract": "Stroke input has a strong advantage relative to the Pinyin input in weight rate.Traditional stroke input method will be optimized in the coding scheme,word thesaurus construction,etc.Then,the user can use stroke to achieve fast text input on the phone.For stroke input coding scheme,a new coding method is designed based on the traditional program.In the structural aspects of the word thesaurus,using a space delimited to realize the strokes phrase,sentence input.Based on the input method design process,the input method of approach on the windows mobile platform was given,users can input a continuous string of strokes,words,phrases and statements can be entered,Chinese character input efficiency is improved.",
        "keywords": [
            "stroke",
            "input method",
            "Windows Mobile",
            "IME"
        ],
        "authors": [
            {
                "name": "YIN Fang-gang",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Ministry of Education Key Laboratory of Intelligent Computing and Signal Processing, Anhui University,Hefei ,China"
            },
            {
                "name": "WU Hai-hui",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Ministry of Education Key Laboratory of Intelligent Computing and Signal Processing, Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2011
    },
    "xfqu59UH": {
        "id": "xfqu59UH",
        "title": "Rice stripe tenuivirus p2 may recruit or manipulate nucleolar functions through an interaction with fibrillarin to promote virus systemic movement: Nucleolus and RSV systemic movement",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "lianhui xie",
                "org": ""
            },
            {
                "name": "zujian wu",
                "org": ""
            },
            {
                "name": "taiyun wei",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "kangcheng wu",
                "org": ""
            },
            {
                "name": "qianzhuo mao",
                "org": ""
            },
            {
                "name": "chen lin",
                "org": ""
            },
            {
                "name": "zhenguo du",
                "org": ""
            },
            {
                "name": "luping zheng",
                "org": ""
            }
        ],
        "venue": "Molecular Plant Pathology",
        "year": 2015
    },
    "xNWzoWf6": {
        "id": "xNWzoWf6",
        "title": "Functional selection of a type IV pili-binding peptide that specifically inhibits Salmonella Typhi adhesion to/invasion of human monocytic cells.",
        "abstract": "Salmonella enterica serovar Typhi (S. Typhi) is an important pathogen which infects humans exclusively and causes typhoid or enteric fever. Recently it has been discovered that type IVB pili, encoded by the S. Typhi pil operon located in the major pathogenicity island, may be important in the pathogenesis of epidemic enteric fever. To further investigate the roles of type IVB pili of S. Typhi, a 12-mer peptide (RQERSSLSKPVV), binding to the structural protein PilS of the type IVB pili of S. Typhi, was isolated with a ribosome display system. This peptide was designated as peptide R. We found that peptide R inhibited adhesion to/invasion of human monocytic THP-1 cells by piliated S. Typhi bacteria, but had no effects on nonpiliated S. Typhi bacteria. A random 12-mer peptide, of size and solubility equal to peptide R, served as a control on the specificity of peptide R. The specific interaction and binding equilibrium between the 12-mer peptide R and PilS protein was determined by isothermal titration calorimetry (ITC) and a binding constant Ka determined to be between 0.4 x 10(5) and 2.2 x 10(5)L mol(-1). Our findings suggest that the type IV pili-binding peptide R holds potential as an antibacterial peptide effective against S. Typhi infections, both in terms of prevention and therapeutic treatment. The data further provide insights into the understanding of the pathogenic roles of the type IVB pili of S. Typhi.",
        "keywords": [
            "binding peptide",
            "ribosome display",
            "salmonella typhi",
            "type ivb pili",
            "isothermal titration calorimetry"
        ],
        "authors": [
            {
                "name": "Hong-Yan Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xiao-Lian Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qin Pan",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Peptides",
        "year": 2005
    },
    "gt6vamnn": {
        "id": "gt6vamnn",
        "title": "A viral protein promotes host SAMS1 activity and ethylene production for the benefit of virus infection.",
        "abstract": "Ethylene plays critical roles in plant development and biotic stress response, but the mechanism of ethylene in host antiviral response remains unclear. Here, we report that  (RDV) triggers ethylene production by stimulating the activity of S-adenosyl-L-methionine synthetase (SAMS), a key component of the ethylene synthesis pathway, resulting in elevated susceptibility to RDV. RDV-encoded Pns11 protein specifically interacted with OsSAMS1 to enhance its enzymatic activity, leading to higher ethylene levels in both RDV-infected and Pns11-overexpressing rice. Consistent with a counter-defense role for ethylene, Pns11-overexpressing rice, as well as those overexpressing , were substantially more susceptible to RDV infection, and a similar effect was observed in rice plants treated with an ethylene precursor. Conversely, knockout mutants, as well as an  mutant defective in ethylene signaling, resisted RDV infection more robustly. Our findings uncover a novel mechanism which RDV manipulates ethylene biosynthesis in the host plants to achieve efficient infection.",
        "keywords": [
            "Oryza sativa",
            "RDV",
            "plant biology",
            "rice virus"
        ],
        "authors": [
            {
                "name": "Shanshan Zhao",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Wei Hong",
                "org": "The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Yu Wang",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Shaoyi Ji",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Shuyi Zhu",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Chunhong Wei",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Jinsong Zhang",
                "org": "State Key Lab of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China."
            },
            {
                "name": "Yi Li",
                "org": "State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            }
        ],
        "venue": "eLife",
        "year": 2017
    },
    "7Y7ZsJdJ": {
        "id": "7Y7ZsJdJ",
        "title": "Defining and measuring urban sustainability: a review of indicators",
        "abstract": "The sustainability of urban areas is essential to the sustainability of regions, nations, and the world as a whole. Urban sustainability indicators (USIs) can play an important role in advancing the science and practice of sustaining urban systems.",
        "keywords": [
            "Urbanization",
            " Urban sustainability indicators",
            " Indicator frameworks",
            " Sustainable cities",
            " Landscape sustainability"
        ],
        "authors": [
            {
                "name": "lu huang",
                "org": "zhejiang university"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "lijiao yan",
                "org": "zhejiang university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "w6sXmLpK": {
        "id": "w6sXmLpK",
        "title": "Influenza A Virus Induces Interleukin-27 through",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "li liu",
                "org": ""
            },
            {
                "name": "zhongying cao",
                "org": ""
            },
            {
                "name": "jing chen",
                "org": ""
            },
            {
                "name": "rui li",
                "org": ""
            },
            {
                "name": "yanhua cao",
                "org": ""
            },
            {
                "name": "chengliang zhu",
                "org": ""
            },
            {
                "name": "kailang wu",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "fang liu",
                "org": ""
            },
            {
                "name": "ying zhu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2012
    },
    "mKGW6Zgr": {
        "id": "mKGW6Zgr",
        "title": "Global regulation of a sigma 54-dependent flagellar gene family in Caulobacter crescentus by the transcriptional activator FlbD.",
        "abstract": "Biosynthesis of the Caulobacter crescentus polar flagellum requires the expression of a large number of flagellar (fla) genes that are organized in a regulatory hierarchy of four classes (I to IV). The timing of fla gene expression in the cell cycle is determined by specialized forms of RNA polymerase and the appearance and/or activation of regulatory proteins. Here we report an investigation of the role of the C. crescentus transcriptional regulatory protein FlbD in the activation of sigma 54-dependent class III and class IV fla genes of the hierarchy by reconstituting transcription from these promoters in vitro. Our results demonstrate that transcription from promoters of the class III genes flbG, flgF, and flgI and the class IV gene fliK by Escherichia coli E sigma 54 is activated by FlbD or the mutant protein FlbDS140F (where S140F denotes an S-to-F mutation at position 140), which we show here has a higher potential for transcriptional activation. In vitro studies of the flbG promoter have shown previously that transcriptional activation by the FlbD protein requires ftr (ftr for flagellar transcription regulation) sequence elements. We have now identified multiple ftr sequences that are conserved in both sequence and spatial architecture in all known class III and class IV promoters. These newly identified ftr elements are positioned ca. 100 bp from the transcription start sites of each sigma 54-dependent fla gene promoter, and our studies indicate that they play an important role in controlling the levels of transcription from different class III and class IV promoters. We have also used mutational analysis to show that the ftr sequences are required for full activation by the FlbD protein both in vitro and in vivo. Thus, our results suggest that FlbD, which is encoded by the class II flbD gene, is a global regulator that activates the cell cycle-regulated transcription from all identified sigma 54-dependent promoters in the C. crescentus fla gene hierarchy.",
        "keywords": [
            "flagella",
            "transcription factors",
            "dna binding proteins",
            "dna primers",
            "structure activity relationship",
            "sigma factor",
            "sequence alignment"
        ],
        "authors": [
            {
                "name": "J Wu",
                "org": "Department of Molecular Biology, Princeton University, New Jersey 08544-1014, USA."
            },
            {
                "name": "A K Benson",
                "org": ""
            },
            {
                "name": "A Newton",
                "org": ""
            }
        ],
        "venue": "Journal of bacteriology",
        "year": 1995
    },
    "NtdOcCFV": {
        "id": "NtdOcCFV",
        "title": "The Root Cause of China's Dairy Industry Crisis and Countermeasures Analysis",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "QIAN Guixia",
                "org": ""
            },
            {
                "name": "GUO Xiaochuan",
                "org": ""
            },
            {
                "name": "WU Jianguo",
                "org": ""
            },
            {
                "name": "GUO Jianjun",
                "org": ""
            }
        ],
        "venue": "Issues in Agricultural Economy",
        "year": 2010
    },
    "aqWkg1JT": {
        "id": "aqWkg1JT",
        "title": "Diagnosis and treatment of femoral hernia in males:a report of 37 cases",
        "abstract": "Objective To study the clinical characteristics,diagnosis and treatment of femoral hernia in males.Methods The clinical data of 37 cases of femoral hernia in males admitted to our department in the last nine years were analyzed retrospectively.Results The clinical manifestations of femoral hernia in males included a reducible mass below the inguinal ligament in all 37 cases,on the right side in 24 cases,and the left side in 13 cases; inguinal pain in 29 cases,incarceration or strangulation in 19 cases,and gut incarceraion with bowel obstruction in 7 cases.Herniorrhaphy was performed in 35 of the patients,including.McVay repair performed in 19 cases,tension-free hernioplasty performed in 13 cases,and femoral herniorrhaphy through an incision below the inguinal ligament performed in 3 cases.All the cases were followed up for 6 months to 5 years,no recurrence was found.Conclusions The diagnosis of in males femoral hernia can be made according to clinical symptoms and signs.Doppler ultrasound examination is helpful for diagnosis of femoral hernia.Herniorrhaphy is the only effective means of treatment of femoral hernia.",
        "keywords": [
            "Masculine/ther",
            "Herniorrhaphy",
            "Masculine/diag",
            "Femoral Hernia"
        ],
        "authors": [
            {
                "name": "WU Jianguo",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "SHEN Xiaojun",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "NIE Mingming",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "XUE Xuchao",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "BI Jianwei",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "FANG Guoen",
                "org": "Department of General Surgery,Affiliated Changhai Hospital,the Second Military Medical University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of General Surgery",
        "year": 2010
    },
    "i2ucYruY": {
        "id": "i2ucYruY",
        "title": "HERP Binds TBK1 To Activate Innate Immunity and Repress Virus Replication in Response to Endoplasmic Reticulum Stress.",
        "abstract": "Host innate immunity is crucial for cellular responses against viral infection sensed by distinct pattern recognition receptors and endoplasmic reticulum (ER) stress. Enterovirus 71 (EV71) is a causative agent of hand, foot, and mouth disease and neurological diseases. However, the exact mechanism underlying the link between ER stress induced by EV71 infection and host innate immunity is largely unknown. In this study, we demonstrated that EV71 infection induces the homocysteine-induced ER protein (HERP), a modulator of the ER stress response which is dependent on the participation of MAVS. Virus-induced HERP subsequently stimulates host innate immunity to repress viral replication by promoting type-I IFNs (IFN-α and IFN-β) and type-III IFN (IFN-λ1) expression. Through interacting with TANK-binding kinase 1, HERP amplifies the MAVS signaling and facilitates the phosphorylation and nuclear translocation of IFN regulatory factor 3 and NF-κB to enhance the expression of IFNs, which leads to a broad inhibition of the replication of RNA viruses, including EV71, Sendai virus, influenza A virus, and vesicular stomatitis virus. Therefore, we demonstrated that HERP plays an important role in the regulation of host innate immunity in response to ER stress during the infection of RNA viruses. These findings provide new insights into the mechanism underlying the replication of RNA viruses and the production of IFNs, and also demonstrate a new role of HERP in the regulation of host innate immunity in response to viral infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Maolin Ge",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Zhen Luo",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Zhi Qiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Yao Zhou",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Xin Cheng",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Qibin Geng",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Yanyan Cai",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Ying Xiong",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and jwu@whu.edu.cn mvlwu@whu.edu.cn wukailang@whu.edu.cn."
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and jwu@whu.edu.cn mvlwu@whu.edu.cn wukailang@whu.edu.cn."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; and jwu@whu.edu.cn mvlwu@whu.edu.cn wukailang@whu.edu.cn."
            }
        ],
        "venue": "Journal of immunology (Baltimore, Md. : 1950)",
        "year": 2017
    },
    "6IAxYMTb": {
        "id": "6IAxYMTb",
        "title": "p2 of rice stripe virus (RSV) interacts with OsSGS3 and is a silencing suppressor.",
        "abstract": "A rice cDNA library was screened by a galactosidase 4 (Gal4)-based yeast two-hybrid system with Rice stripe virus (RSV) p2 as bait. The results revealed that RSV p2 interacted with a rice protein exhibiting a high degree of identity with Arabidopsis thaliana suppressor of gene silencing 3 (AtSGS3). The interaction was confirmed by bimolecular fluorescence complementation assay. SGS3 has been shown to be involved in sense transgene-induced RNA silencing and in the biogenesis of trans-acting small interfering RNAs (ta-siRNAs), possibly functioning as a cofactor of RNA-dependent RNA polymerase 6 (RDR6). Given the intimate relationships between virus and RNA silencing, further experiments were conducted to show that p2 was a silencing suppressor. In addition, p2 enhanced the accumulation and pathogenicity of Potato virus X in Nicotiana benthamiana. Five genes that have been demonstrated to be targets of TAS3-derived ta-siRNAs were up-regulated in RSV-infected rice. The implications of these findings are discussed.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhenguo Du",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Donglai Xiao",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Dongsheng Jia",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Zhengjie Yuan",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Ying Liu",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Liuyang Hu",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Zhao Han",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Taiyun Wei",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Qiying Lin",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Zujian Wu",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            },
            {
                "name": "Lianhui Xie",
                "org": "Fujian Agriculture and Forestry University(Fujian Agriculture and Forestry University),Fuzhou,China"
            }
        ],
        "venue": "Molecular plant pathology",
        "year": 2011
    },
    "BtiSHGJo": {
        "id": "BtiSHGJo",
        "title": "Potential Effects of Climate Change on the Distribution of Seven Protected Plants in China",
        "abstract": "The effects of climate change on the distributions of Alsophila spinulosa(Alsophila spinulosa(Wall.Ex Hook.) Tryon),Tetracentron(Tetracentron sinense Oliv),Dipentondon(Dipentondon sinicus Dunn) Wingceltis(Pteroceltis tatarinowii Maxim),common peach-seven(Sinopodophyllum emodi(Wall.)Ying),Chinese larch(Larix chinensis Beissn) and Henry Wilsontree(Sinowilsonia henryi Hemsl) from China were analyzed using the classification and regression tree(CART) niche model and climate change scenarios of A2 and B2.The results showed that climate change will cause a decrease in the current Chinese distribution of these plants.Chinese larch,Henry Wilsontree or Tetracentron exhibited the largest decrease,Dipentondon and Wingceltis was lower than Chinese larch,Henry Wilsontree,and Tetracentron,and the decrease of Alsophila spinulosa and common peach-seven showed the smallest decrease.The new and total distribution region of Chinese larch or Henry Wilsontree decreased from 1991-2020 and 2081-2100,while the remaining plants increased from 1991-2020 and 2081-2100,and they were higher in A2 scenario than those in B2 Scenario.Following climate change,distribution regions of Chinese larch would be mostly lost.The current distribution regions in the southwest,southeast,south and west of the other plant species would be reduced,while new distribution regions would expand towards the west,northwest,north,northeast,and southeast.Additionally,the current,new,and total distribution of the plants were either poorly related to or did not change consistently with the change in annual mean air temperature or precipitation.The linear relationships between the change in plant distribution and annual mean temperature and annual mean precipitation in China were poor except for the linear relationships between the change in the new or total distribution of Alsophila spinulosa and current distribution of Dipentondon and common peach-seven with annual mean air temperature or annual mean precipitation change in China.The results indicated that climate change in China will cause changes in spatial distribution pattern of these plants,decrease their current distribution regions,decrease new distribution of Chinese larch and Henry Wilsontree,and increase new distribution of the other plants.",
        "keywords": [
            "Protected Plants",
            "Climate Change",
            "Potential effects",
            "Distribution"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Wuhan Botanical Research",
        "year": 2010
    },
    "VdqdKpU8": {
        "id": "VdqdKpU8",
        "title": "High-Moment Method for Structural Reliability of the Stability of Reticulated Shell Structures",
        "abstract": "In structural reliability compute of the stability of reticulated shell structure,the cumulative distribution functions of random variables is difficult to know.So the structural reliability analysis of the stability of the reticulated shell structures is very difficult.In the present paper,based on the computer model of the stability of the reticulated shell structures,the normal transformation for the random variables with the unknown cumulative distribution functions can be realized with high moment.Through example presented,the proposed method is found to be sufficiently accurate to the reliability compute with little extra computational effort.",
        "keywords": [
            "stability of reticulated shell structure",
            "first-order second-moment reliability",
            "reliability",
            "third-moment",
            "fourth-moment"
        ],
        "authors": [
            {
                "name": "LOU Wei",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jun-jie",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Building Science",
        "year": 2010
    },
    "xOGkaNir": {
        "id": "xOGkaNir",
        "title": "Screening of Solid Fermentation Strain for Function Product of Kudzu Residue",
        "abstract": "Kudzu residue extracted starch is rich in kudzu isoflavone and dietary fiber, which is not yet adequately used. The aim of this paper is to obtain a high efficiency strain from ten edible and medicinal mushrooms which can ferment kudzu residue to produce function product. Through systematic study, the content of kudzu dietary fiber was increased after strain DS1 or En2 fermented kudzu residue among ten edible and medicinal mushrooms. The quality of the fermentation product is good, especially strain DS1, which remarkably increased the content of kudzu isoflavone after the kudzu residue was fermented. At last, content of dietary fiber and isoflavone of kudzu residue were 108.8% and 130.3% respectively after kudzu residue was fermented by strain DS1. Strain DS1 was the high efficiency strain for kudzu residue fermentation.",
        "keywords": [
            "solid fermentation",
            "edible and medicinal mushroom",
            "dietary fiber",
            "kudzu residue",
            "strain screening",
            "isoflavone"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "School of Life Science and Technology, Huazhong University of Science and Technology, Hubei , China"
            },
            {
                "name": "Zhu Zhiguang",
                "org": "School of Life Science and Technology, Huazhong University of Science and Technology, Hubei , China"
            },
            {
                "name": "Jia Weiyan",
                "org": "School of Life Science and Technology, Huazhong University of Science and Technology, Hubei , China"
            },
            {
                "name": "Hu Yang",
                "org": "School of Life Science and Technology, Huazhong University of Science and Technology, Hubei , China"
            },
            {
                "name": "Zhang Xiaoyu",
                "org": "School of Life Science and Technology, Huazhong University of Science and Technology, Hubei , China"
            }
        ],
        "venue": "Food and Fermentation Industries",
        "year": 2009
    },
    "LvvsoWtX": {
        "id": "LvvsoWtX",
        "title": "Analysis and Improvement of Linux Kernel 2.6 Process Scheduler",
        "abstract": "Expresses the analysis of Linux kernel 2.6 process scheduler,elaborates the reasons of the improvement of Linux kernel 2.6's real-time performance.And point out three basic scheduling policies: SCHED-OTHER,SCHED-FIFO,SCHED-RR have the problem of real-time scheduler,then expresses four kinds of scheduling algorithm to improve this defect: RM algorithm based on static priority,EDF,LSF algorithm based on dynamic priority and a mixed algorithm.These four algorithms all improve Linux kernel2.6's real-time performance on different level.For letting Linux use better in real-time system,now should study more effective and useful scheduling algorithm to improve Linux real-time performance.",
        "keywords": [
            "process",
            "scheduling algorithm",
            "Linux kernel 2.6",
            "real-time"
        ],
        "authors": [
            {
                "name": "YANG Jing",
                "org": "Key Lab.of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Key Lab.of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "WAN Feng-song",
                "org": "Key Lab.of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Lab.of Intelligent Computing & Signal Processing,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2009
    },
    "m6jQbX07": {
        "id": "m6jQbX07",
        "title": "Effects of thematic resolution on landscape pattern analysis",
        "abstract": "The thematic resolution of mapped data determines the amount of detail of geospatial information, and influences various aspects\n of landscape classification and the relevance of derived pattern attributes to particular ecological questions. Here we show\n that changing thematic resolution may significantly affect landscape metrics and in turn their ability to detect landscape\n changes. The effects of thematic resolution on many landscape metrics tend to show consistent general patterns, but the details\n of these patterns are likely to be dependent on specific landscape patterns and classification criteria. Thus, the effects\n of thematic resolution, like those with regard to grain and extent, must be considered in landscape pattern analysis.",
        "keywords": [
            "landscape characterization æ image classification æ thematic resolution æ landscape metrics æ landscape pattern analysis",
            "image classification"
        ],
        "authors": [
            {
                "name": "Alexander Buyantuyev",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability Tempe AZ 85287-4501 USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability Tempe AZ 85287-4501 USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2007
    },
    "ELAeyMDg": {
        "id": "ELAeyMDg",
        "title": "Hierarchical plant responses and diversity loss after nitrogen addition: testing three functionally-based hypotheses in the Inner Mongolia grassland.",
        "abstract": "Numerous studies have shown that nitrogen (N) deposition decreases biodiversity in terrestrial ecosystems. To explain the N-induced species loss, three functionally based hypotheses have been proposed: the aboveground competition hypothesis, the belowground competition hypothesis, and the total competition hypothesis. However, none of them is supported sufficiently by field experiments. A main challenge to testing these hypotheses is to ascertain the role of shoot and root competition in controlling plant responses to N enrichment. Simultaneously examining both aboveground and belowground responses in natural ecosystems is logistically complex, and has rarely been done.In a two-year N addition experiment conducted in a natural grassland ecosystem, we investigated both above- and belowground responses of plants at the individual, species, and community levels. Plants differed significantly in their responses to N addition across the different organizational levels. The community-level species loss was mainly due to the loss of perennial grasses and forbs, while the relative abundance of plant species was dependent mainly on individual-level responses. Plasticity in biomass allocation was much smaller within a species than between species, providing a biological basis for explaining the functionally based species loss. All species increased biomass allocation to aboveground parts, but species with high belowground allocations were replaced by those with high aboveground allocations, indicating that the increased aboveground competition was the key process responsible for the observed diversity loss after N addition in this grassland ecosystem.Our findings shed new light on the validity of the three competing hypotheses concerning species loss in response to N enrichment. They also have important implications for predicting the future impacts of N deposition on the structure and functioning of terrestrial ecosystems. In addition, we have developed a new technique for ascertaining the roles of aboveground and belowground competition in determining plant responses to N fertilization.",
        "keywords": [
            "biology",
            "chemistry",
            "nitrogen",
            "perennial grass",
            "medicine",
            "field experiment",
            "engineering",
            "relative abundance",
            "terrestrial ecosystems",
            "physics"
        ],
        "authors": [
            {
                "name": "Qingmin Pan",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Yongfei Bai",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Xingguo Han",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "PloS one",
        "year": 2011
    },
    "hkH4U4ng": {
        "id": "hkH4U4ng",
        "title": "SUMO1 SUMOylates and SENP3 deSUMOylates NLRP3 to orchestrate the inflammasome activation.",
        "abstract": "The NLRP3 inflammasome regulates innate immune and inflammatory responses by promoting caspase1-dependent induction of pro-inflammatory cytokines. However, aberrant inflammasome activation causes diverse diseases, and thus inflammasome activity must be tightly controlled. Here, we reveal a molecular mechanism underlying the regulation of NLRP3 inflammasome. NLRP3 interacts with SUMO-conjugating enzyme (UBC9), which subsequently promotes small ubiquitin-like modifier 1 (SUMO1) to catalyze NLRP3 SUMOylation at residue Lys. SUMO1-catalyzed SUMOylation of NLRP3 facilitates ASC oligomerization, inflammasome activation, and interleukin-1β secretion. Moreover, this study also reveals that SUMO-specific protease 3 (SENP3) is required for the deSUMOylation of NLRP3. Interestingly, SENP3 deSUMOylates NLRP3 to attenuate ASC recruitment and speck formation, the NLRP3 inflammasome activation, as well as IL-1β cleavage and secretion. In conclusion, we reveal that SUMO1-catalyzed SUMOylation and SENP3-mediated deSUMOylation of NLRP3 orchestrate the inflammasome activation.",
        "keywords": [
            "SUMO1‐catalyzed SUMOylation",
            "inflammasome",
            "innate immune response",
            "interleukin‐1β",
            "posttranslational modification"
        ],
        "authors": [
            {
                "name": "Luyao Shao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yan Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Aixin Li",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Muhammad Adnan Shereen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wen Zhang",
                "org": "Guangdong LongFan Biological Science and Technology Company, Foshan, China."
            },
            {
                "name": "Quiping Tan",
                "org": "Guangdong LongFan Biological Science and Technology Company, Foshan, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
        "year": 2020
    },
    "qBzjGJY6": {
        "id": "qBzjGJY6",
        "title": "Selective cytolysis of tumor cells by mumps virus S79.",
        "abstract": "We studied the sensitivity of several human cancer cell strains (HeLa, HT1080, SPC-A1, and ACHN) and normal cell strains (MRC-5 and Wish) to mumps virus (MuV) S79, a live attenuated vaccine strain. These cells exhibited a differential sensitivity to infection with MuV, and the susceptible sequences were ACHN > HeLa > HT1080 > SPC-A1 > Wish > MRC-5. In experiments in vivo, nude mice with HT1080 fibrosarcoma xenografts were randomly divided into three groups for intratumoral treatment with MuVS79, UV-inactivated MuVS79, and PBS. At 10(7) PFU, live MuVS79 injection caused in 7 of 9 mice complete regression by day 15 while rapid tumor growth occurred in all 9 mice treated with PBS. Rapid tumor progression also occurred in all 8 mice treated with UV-inactivated virus; however, tumor growth was delayed in the logarithmic phase relative to the PBS-treated tumors.",
        "keywords": [
            "vaccines",
            "mumps virus s79",
            "cytolytic virus",
            "tumor treatment",
            "virus",
            "cancer",
            "live attenuated"
        ],
        "authors": [
            {
                "name": "Yin-Fang Yan",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xiao Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Chang-Yuan Dong",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Intervirology",
        "year": 2005
    },
    "ZJqP7Zy7": {
        "id": "ZJqP7Zy7",
        "title": "Detecting and attributing the effect of climate change on the changes in the distribution of Qinghai-Tibet plateau large mammal species over the past 50 years",
        "abstract": "The effects of prior climate change on large mammal distributions are uncertain. We evaluated the relationship between the changes in the distribution of Qinghai-Tibet plateau large mammals and climate change over the past 50 years and examined whether these changes can be attributed to climate change in China. Long-term distribution records of mammal species, grey relational analyses, the fuzzy-set classification technique, the consistency index, and attribution methods were used. Over the past 50 years, the mammal distributions have primarily shifted eastward or westward, and most of these changes are correlated with the thermal index. In response to climate change over the past years, the distribution boundary and the distribution center of particular species have changed and have exhibited fluctuations. The observed and predicted changes in the distributions were highly consistent for certain species. The changes in the southern limit, western limit, or center latitude of the distribution of some mammal species can be attributed to climate change.",
        "keywords": [
            "Biodiversity",
            " Consistency index",
            " Climatic factors",
            " Distributional change",
            " Fuzzy-set classification",
            " Grey relational analysis"
        ],
        "authors": [
            {
                "name": "jianguo wu",
                "org": "The Center for Climate Change,Chinese Research Academy of Environmental Sciences,Beijing,China"
            }
        ],
        "venue": "",
        "year": 2015
    },
    "XNQsikA9": {
        "id": "XNQsikA9",
        "title": "Antioxidant and Hepatoprotective Activities of Crude Polysaccharide Extracts from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), by Ultrasonic-Circulating Extraction.",
        "abstract": "We recently proposed, and successfully applied, a novel and efficient technique-ultrasonic-circulating extraction (UCE) integrating superfine pulverization-to extract and prepare antioxidant crude polysaccharides other natural active substances from Ganoderma lucidum. The aim of this study was to evaluate the antioxidant and hepatoprotective activities and active ingredients in the powder from UCE (UCEP) through comparison with powder from hot water extraction (HWEP). The DPPH radical, ABTS radical, superoxide anion, total antioxidant activity, and ferric-reducing antioxidant power assay results showed that the UCEP exhibited stronger (P < 0.01) in vitro antioxidant activity than the HWEP. The hepatoprotective activity of the extracts was evaluated against CCl4-induced oxidative damage in the liver. Measurements of reduced glutathione, superoxide dismutase, and malondialdehyde in rat liver; measurements of alanine transaminase, aspartate transaminase, and lactate dehydrogenase in rat blood; and Western blotting for antioxidant proteins of transforming growth factor-β1, heme-oxygenase 1, and glutathione per-oxidase showed that the UCEP had antioxidant activity in vivo either similar to or slightly stronger than (P < 0.1) the HWEP. Further analysis of the active ingredients revealed that the UCEP and HWEP have similar mean yield and total triterpenoid content, but the former has significantly higher (P < 0.05) mean yield and total polysaccharide content than the latter. Our results suggest that the UCEP displays stronger antioxidant activities because of the larger amount of total polysaccharides; the UCEP may be able to be used as an antioxidant and liver protectant.",
        "keywords": "",
        "authors": [
            {
                "name": "Ti Qiang Chen",
                "org": "Institute of Edible and Medicinal Fungi, Fujian Academy of Agricultural Sciences, Fuzhou, China."
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Fujian University of Traditional Chinese Medicine, Fuzhou, China."
            },
            {
                "name": "Yong-Jun Kan",
                "org": "Fujian University of Traditional Chinese Medicine, Fuzhou, China."
            },
            {
                "name": "Chi Yang",
                "org": "Institute of Edible and Medicinal Fungi, Fujian Academy of Agricultural Sciences, Fuzhou, China."
            },
            {
                "name": "Yan-Bin Wu",
                "org": "Fujian University of Traditional Chinese Medicine, Fuzhou, China."
            },
            {
                "name": "Jin-Zhong Wu",
                "org": "Fujian University of Traditional Chinese Medicine, Fuzhou, China."
            }
        ],
        "venue": "International journal of medicinal mushrooms",
        "year": 2018
    },
    "UpO2THaS": {
        "id": "UpO2THaS",
        "title": "Study of multi-step forming processes based on the dynamic simulation",
        "abstract": "By analyzing stamping processes of the co mplicated stamping work-piece,shapes and dimensions of the semi-finished produ cts of every stamping process are defined preliminarily.According to the shapes and the dimensions of the semi-finished products,the simulations for the stampi ng processes are carried out.The reasonableness of the stamping processes is ana lyzed.The suitable stamping scheme is obtained by means of modifying the paramet ers of the semi-finished products.The die sets are fabricated based on the sche me and the qualified product can be stamped out.Described the dynamic simulation method of the multi-step forming and the design approach of the stamping proce ss .It makes die sets designed successful at the presence of time saved and cost effective.",
        "keywords": [
            "Multi-step forming",
            "Dynamic simulation Multi-step forming Deep drawing",
            "Dynamic simulation",
            "Deep drawing"
        ],
        "authors": [
            {
                "name": "Wang Yanhui",
                "org": "Department of Mechanical & Electrical Engineering, Shazh ou Institute of Technology,Zhangjiagang ,CHN"
            },
            {
                "name": "Miao Xiaoming",
                "org": "Department of Mechanical & Electrical Engineering, Shazh ou Institute of Technology,Zhangjiagang ,CHN"
            },
            {
                "name": "Wang Chengming",
                "org": "Department of Mechanical & Electrical Engineering, Shazh ou Institute of Technology,Zhangjiagang ,CHN"
            },
            {
                "name": "Wu Jianguo",
                "org": "Department of Mechanical & Electrical Engineering, Shazh ou Institute of Technology,Zhangjiagang ,CHN"
            }
        ],
        "venue": "Modern Manufacturing Engineering",
        "year": 2005
    },
    "EmJCznkr": {
        "id": "EmJCznkr",
        "title": "NS5A protein of HCV enhances HBV replication and resistance to interferon response.",
        "abstract": "HCV and HBV are the major causes of chronic liver diseases worldwide. Patients with both viruse's co-infection tend to develop severer liver diseases and are at high risk of liver-related death. NS5A protein of HCV plays key roles in HCV replication and inhibition of host immune responses. In this study, we described the establishment of HepG2-derived cell line that stably expresses NS5A protein and the application of a cellular system for HBV replication based on a recombinant adenovirus carrying HBV genome. Our results demonstrated that NS5A enhances the expression of S and E proteins of HBV, as well as the synthesis of viral DNA. Moreover, we showed that NS5A assists HBV to escape interferon responses. These data suggested that NS5A of HCV may employ multiple strategies contributing to the enhancement of HBV replication and interferon resistance during the co-infection of HCV and HBV.",
        "keywords": [
            "co-infection",
            "interferon",
            "viral gene expression",
            "hcv",
            "hbv replication",
            "hbv",
            "cell line",
            "gene expression",
            "immune response"
        ],
        "authors": [
            {
                "name": "Ying Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Wei Wei",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Lei Kang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Zhongqiang Wang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jiali Fang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Biochemical and biophysical research communications",
        "year": 2007
    },
    "UYIcZz7z": {
        "id": "UYIcZz7z",
        "title": "Improvement and optimization for &quot;genetics&quot; course teaching]",
        "abstract": "\"Genetics\" is one of the main courses for the study scheme of undergraduate students in university. This paper pointed out some problems found in the teaching process according to the characteristics of \"Genetics\" course. At the same time, the thought on the construction of \"Genetics\" course were discussed concerning the reform of course contents, the improvement of teaching method, the creation of teaching CAI (computer assisted instruction), the compile of electronic edition for teaching materials, the evaluation of teaching level, the innovation of experimental contents and the methods for improving the teaching effect.",
        "keywords": [],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": "Agronomy Department, Zhejiang University, Hangzhou 310029, China. chhshi@zju.edu.cn"
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Qiu-Lan Ma",
                "org": ""
            },
            {
                "name": "Jian-Fu Xiao",
                "org": ""
            },
            {
                "name": "Cai-Xia Hong",
                "org": ""
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2005
    },
    "NCkXQZE0": {
        "id": "NCkXQZE0",
        "title": "Interactions of ecosystem processes with spatial heterogeneity in the puzzle of nitrogen limitation",
        "abstract": "We examined the potential effects of spatial heterogeneity and its development on the distribution, abundance, and functioning of nitrogen fixing and non-fixing components of a model ecosystem. CAECO, a spatially explicit individual based model approach, simulated the interactions between nitrogen fluxes and plant species community dynamics. Self-organized spatial patterns of nitrogen concentrations and plant occupancy were observed as the system approached an apparently meta-stable state. Nitrogen limitation was tested using chronic and gradient nitrogen amendments to the landscape. The dynamic arrangement of ecosystem components was sufficient to maintain indefinite nitrogen limitation at a local scale. However, landscape scale productivity was not similarly increased with nitrogen amendments. Landscape productivity was independent of nitrogen additions while fixers were present in the ecosystem. The probability of fixer loss from the system responded non-linearly to increasing nitrogen addition. The results of these model experiments suggest local and landscape constraints of primary productivity may be fundamentally distinct.",
        "keywords": [
            "spatial pattern",
            "primary production",
            "spatial heterogeneity",
            "self organization",
            "nitrogen"
        ],
        "authors": [
            {
                "name": "G. Darrel Jenerette",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Oikos",
        "year": 2004
    },
    "0vQD1uPr": {
        "id": "0vQD1uPr",
        "title": "Giant Merkel cell carcinoma of the eyelid: a case report and review of the literature.",
        "abstract": "Merkel cell carcinoma (MCC) is a rare cutaneous tumor and cases located in the eyelid have been described, but still its rarity may lead to difficulty in diagnosis and delay in treatment. A 51-year-old female patient that presented with large lesions in the eyelid underwent surgery after the diagnosis of acute chalazion. Following respiratory distress secondary to pulmonary metastasis, the patient's condition deteriorated and was not fit for complete excision treatment. Histopathological investigation of the biopsies, taken from the tumor, revealed that it was undifferentiated small cell carcinoma. Our aim with this paper is to point out that more cases should be reported for more effective diagnosis, histopathological study, clinical investigation, treatment and prognosis of this specific neoplasm.",
        "keywords": [
            "merkel cell carcinoma eyelid tumor",
            "histopatholog",
            "diagnosis"
        ],
        "authors": [
            {
                "name": "Luxia Chen",
                "org": "TianJin Medical University Eye Center, 300084 TianJin, P.R. China"
            },
            {
                "name": "Limin Zhu",
                "org": "TianJin Medical University Eye Center, 300084 TianJin, P.R. China"
            },
            {
                "name": "Jianguo Wu",
                "org": "TianJin Medical University Eye Center, 300084 TianJin, P.R. China"
            },
            {
                "name": "Tingting Lin",
                "org": "TianJin Medical University Eye Center, 300084 TianJin, P.R. China"
            },
            {
                "name": "Baocun Sun",
                "org": "Department of Pathology of TianJin Medical University, TianJin Cancer Hospital, 300060 TianJin, P.R. China"
            },
            {
                "name": "Yanjin He",
                "org": "TianJin Medical University Eye Center, 300084 TianJin, P.R. China"
            }
        ],
        "venue": "World journal of surgical oncology",
        "year": 2011
    },
    "78QPdqgz": {
        "id": "78QPdqgz",
        "title": "Oral Delivery of a Novel Attenuated Salmonella Vaccine Expressing Influenza A Virus Proteins Protects Mice against H5N1 and H1N1 Viral Infection",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zenglin pei",
                "org": "wuhan university"
            },
            {
                "name": "xiaohong jiang",
                "org": "university of california berkeley"
            },
            {
                "name": "zhu yang",
                "org": ""
            },
            {
                "name": "xiaoguang ren",
                "org": "wuhan university"
            },
            {
                "name": "hao gong",
                "org": "university of california berkeley"
            },
            {
                "name": "michael reeves",
                "org": "university of california berkeley"
            },
            {
                "name": "jingxue sheng",
                "org": "university of california berkeley"
            },
            {
                "name": "yu wang",
                "org": ""
            },
            {
                "name": "zishu pan",
                "org": "wuhan university"
            },
            {
                "name": "fenyong liu",
                "org": "university of california berkeley"
            },
            {
                "name": "jianguo wu",
                "org": "wuhan university"
            },
            {
                "name": "sangwei lu",
                "org": "university of california berkeley"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2015
    },
    "ZMGOg9LP": {
        "id": "ZMGOg9LP",
        "title": "An Efficient Algorithm to Search for Minimal Closed in Incompletely Specified Finite Sequential Machines",
        "abstract": "It is very important for circuit complexity by state reduction in finite state machine(FSM)synthesis.Be- cause of EDA development,it needs an efficient algorithm for very large FSM.The good algorithm has been found for completely specified FSM,but it is difficult for incompletely specified FSM.This paper gives an efficient algo- rithm for state minimization of incompletely specified finite state machine.The algorithm utilizes generating se- quence,dynamically constructing searching-tree,pruning,heuristically depth-first searching,and branch bounding methods to reduce the search space and raise speed.",
        "keywords": [
            "state reduction",
            "Finite State Machine(FSM)",
            "Incompletely Specified finite State Machine(ISSM)"
        ],
        "authors": [
            {
                "name": "LI Wei",
                "org": "Anhui Univ.,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Anhui Univ.,Hefei ,China"
            }
        ],
        "venue": "Journal of Sichuan University(Engineering Science Edition)",
        "year": 2007
    },
    "PkcMTnAG": {
        "id": "PkcMTnAG",
        "title": "SIRT1 inhibits EV71 genome replication and RNA translation by interfering with the viral polymerase and 5′UTR RNA",
        "abstract": "ABSTRACT  Enterovirus 71 (EV71) possesses a single-stranded positive RNA genome that contains a single open reading frame (ORF) flanked by a 5′ untranslated region (5′UTR) and a polyadenylated 3′UTR. Here, we demonstrated that EV71 activates the production of silent mating type information regulation 2 homolog 1 (SIRT1), a histone deacetylase (HDAC). EV71 further stimulates SIRT1 sumoylation and deacetylase activity, and enhances SIRT1 translocation from the nucleus to the cytoplasm. More interestingly, activated SIRT1 subsequently binds with the EV71 3D pol  protein (a viral RNA-dependent RNA polymerase, RdRp) to repress the acetylation and RdRp activity of 3D pol , resulting in the attenuation of viral genome replication. Moreover, SIRT1 interacts with the cloverleaf structure of the EV71 RNA 5′UTR to inhibit viral RNA transcription, and binds to the internal ribosome entry site (IRES) of the EV71 5′UTR to attenuate viral RNA translation. Thus, EV71 stimulates SIRT1 production and activity, which in turn represses EV71 genome replication by inhibiting viral polymerase, and attenuates EV71 RNA transcription and translation by interfering with viral RNA. These results uncover a new function of SIRT1 and reveal a new mechanism underlying the regulation of EV71 replication.",
        "keywords": "",
        "authors": [
            {
                "name": "Yang Han",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Lvyin Wang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Jin Cui",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Yu Song",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Zhen Luo",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Ying Xiong",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Wenzhe Ho",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University"
            }
        ],
        "venue": "Journal of Cell Science",
        "year": 2016
    },
    "Txytl1oE": {
        "id": "Txytl1oE",
        "title": "An explicit index for assessing the accuracy of cover-class areas",
        "abstract": "We present a new index, called Relative Errors of Area (REA), for assessing the accuracy of cover-class areal percentage (%LAND) that is extracted from thematic maps after classifying remotely sensed data. We demonstrate how to derive REA from an error matrix and its relationship with user's and producer's accuracy. We compare the REA index with other accuracy indices in a hypothetical and two real case studies. The accuracy of cover-class areal estimates is highly correlated with the REA index, but not with other classification accuracy indices such as the overall classification accuracy. In general, users should beware of using thematic maps with low REA values. Moreover, the estimates of cover-class area can be revised by using REA if cell values of the major diagonal in an error matrix are available.",
        "keywords": [],
        "authors": [
            {
                "name": "Guofan Shao",
                "org": "Shenyang Institute of Applied Ecology Chinese Academy of Sciences(Chinese Academy of Sciences),Shenyang,China"
            },
            {
                "name": "Wenchun We",
                "org": "Purdue University(Purdue University,Purdue Univ),West Lafayette,United States"
            },
            {
                "name": "Gang Wu",
                "org": "Research Center for Eco-Environmental Sciences Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xinhua Zhou",
                "org": "University of Nebraska - Lincoln(University of Nebraska,University of Nebraska-Lincoln),Lincoln,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            }
        ],
        "venue": "Photogrammetric Engineering and Remote Sensing",
        "year": 2003
    },
    "cXhJVbKT": {
        "id": "cXhJVbKT",
        "title": "Scaling and Uncertainty Analysis inEcology",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University, Tempe, AZ, U.S.A."
            },
            {
                "name": "Harbin Li",
                "org": "Miami University, Oxford, OH, U.S.A."
            },
            {
                "name": "Orie L. Loucks",
                "org": "A C.I.P. Catalogue record for this book is available from the Library of Congress."
            },
            {
                "name": "K. Bruce Jones",
                "org": ""
            }
        ],
        "venue": "",
        "year": 0
    },
    "SxbwdL6V": {
        "id": "SxbwdL6V",
        "title": "Linking landscape, land system and design approaches to achieve sustainability",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ, USA"
            }
        ],
        "venue": "Journal of Land Use Science",
        "year": 2019
    },
    "MvFk2PD6": {
        "id": "MvFk2PD6",
        "title": "Past, present and future of landscape ecology",
        "abstract": "",
        "keywords": [
            "landscape ecology"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability Tempe AZ 85287-4501 USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2007
    },
    "BCxmxtcV": {
        "id": "BCxmxtcV",
        "title": "Rice ragged stunt virus segment S6-encoded nonstructural protein Pns6 complements cell-to-cell movement of Tobacco mosaic virus-based chimeric virus.",
        "abstract": "The protein(s) that support intercellular movement of Rice ragged stunt virus (RRSV) have not yet been identified. In this study, the role of three nonstructural proteins Pns6, Pns7 and Pns10 in cell-to-cell movement were determined with a movement-deficient Tobacco mosaic virus (TMV) vector. The results showed that only the Pns6 could complement the cell-to-cell movement of the movement-deficient TMV in Nicotiana tabacum Xanthi nc and N. benthamiana plants, and both N- and C-terminal 50 amino acids of Pns6 were essential for the cell-to-cell movement. Transient expression in epidermal cells from N. benthamiana showed that the Pns6-eGFP fusion protein was present predominantly along the cell wall as well as a few punctate sites perhaps indicating plasmodesmata. Taken together with previous finding that the Pns6 has nucleic acid-binding activity (Shao et al., 2004), the possible role of Pns6 in cell-to-cell movement of RRSV were discussed.",
        "keywords": [
            "rice ragged stunt virus",
            "pns6",
            "cell-to-cell movement",
            "tobacco mosaic virus",
            "fusion protein",
            "nucleic acid",
            "amino acid",
            "epidermal cells",
            "cell wall"
        ],
        "authors": [
            {
                "name": "Zujian Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Scott Adkins",
                "org": "United States Department of Agriculture, Agricultural Research Service, 2001 South Rock Road, Fort Pierce, FL 34945, USA"
            },
            {
                "name": "Lianhui Xie",
                "org": ""
            },
            {
                "name": "Weimin Li",
                "org": ""
            }
        ],
        "venue": "Virus research",
        "year": 2010
    },
    "bGbPgxcb": {
        "id": "bGbPgxcb",
        "title": "A multilevel analysis of effects of land use policy on land-cover change and local land use decisions",
        "abstract": "",
        "keywords": [
            "desertification"
        ],
        "authors": [
            {
                "name": "jing zhang",
                "org": ""
            },
            {
                "name": "jianming niu",
                "org": ""
            },
            {
                "name": "alexander buyantuev",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            }
        ],
        "venue": "Journal of Arid Environments",
        "year": 2014
    },
    "sj2uMjHE": {
        "id": "sj2uMjHE",
        "title": "TRAF-interacting-motifs are required for the interaction of MAVS with GP73.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Xuewu",
                "org": ""
            },
            {
                "name": "Zhu Chengliang",
                "org": ""
            },
            {
                "name": "Wang Tianci",
                "org": ""
            },
            {
                "name": "Jiang Hui",
                "org": ""
            },
            {
                "name": "Ren Yahui",
                "org": ""
            },
            {
                "name": "Zhang Qi",
                "org": ""
            },
            {
                "name": "Wu Kailang",
                "org": ""
            },
            {
                "name": "Liu Fang",
                "org": ""
            },
            {
                "name": "Liu Yingle",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            }
        ],
        "venue": "PLOS Pathogens",
        "year": 2017
    },
    "QJBWb0Cu": {
        "id": "QJBWb0Cu",
        "title": "Cooperation between Enterprise and College for Cultivating the Double-Qualified Faculty",
        "abstract": "With analysis of the requirements of the double-qualified faculty,the objective of higher education for vocational graduates,the relationship between knowledge and abilities,this paper concludes the necessity of reforming the current faculty administration and establishing a governmental system for cultivating the double-qualified faculty.Colleges need to focus on teachers' sense of engineering practice and vocational abilities.The cooperation between enterprise and college conduces to the improvement of double-qualified faculty.",
        "keywords": [
            "Cultivation of Double-Qualified Faculty",
            "Professional College Education",
            "Enterprise-&-College Cooperation"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "SHI Zhi-tao",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2011
    },
    "cWS9afRy": {
        "id": "cWS9afRy",
        "title": "Construction of Id3-EGFP eukaryotic expression vector and its expression in A549 cells",
        "abstract": "Objective To construct eukaryotic expression vector for human differentiation inhibitor3(Id3) fused with enhanced green fluorescent protein (EGFP) and express the fusion protein Id3-EGFP in A549 cells. Methods The human Id3 cDNA was amplified and inserted into the pEGFP-N1 vector to construct the recombinant eukaryotic expression vector pEGFP/Id3. The fusion protein Id3-EGFP was expressed in A549 cells by transfection of Id3/pEGFP into the cells. Results The pEGFP/Id3 recombinant expression vector was constructed and confirmed by DNA sequencing、enzymatic digestion and PCR identification. Both pEGFP-N1 and pEGFP/Id3 were transfected into human A549 cells by Lipofectamine~ TM 2000. Flow cytometry analysis revealed that 48 h after transfection, the proportions of EGFP+ cells of pEGFP-N1 and pEGFP/Id3 transfected cells were about 65.40% and 60.50% respectively.The cell proportions in S phase and G2 phase increased in A549 transfected with Id3/pEGFP in comparison with A549 cells transfected with pEGFG-N1 or no transfected. These findings suggested that transfection of Id3 gene into A549 induced cell proliferation by increasing the number of cells from G1 phase to G2 phases. Conclusion The construction of pEGFP/Id3 eukaryotic expression vector and expression of Id3-EGFP fusion protein in A549 cells provide a foundation for the further study of the relationship between Id3 and growth and proliferation of tumor cells.",
        "keywords": [
            "recombinant fusion protein",
            "differentiation inhibitor",
            "Lung neoplasms"
        ],
        "authors": [
            {
                "name": "LI Xiao-jun",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "WANG Ping",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "JIA Li",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "MA Bai-kun",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "XIA Xin-yi",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "YU W",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": " Institute of Clinical Medical Laboratory Medicine of People′s Liberation Army,Nanjing General Hospital of Nanjing Command, Nanjing ,China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Medicine",
        "year": 2006
    },
    "4P2stcX5": {
        "id": "4P2stcX5",
        "title": "Study on ultrasonic extraction technology of chitosan from Mucor racemosus",
        "abstract": "The extraction conditions of chitosan by ultrasonic extraction were studied in this paper.The optimal extraction solution was 0.8mol/L NaOH and the volume ratio of cell and NaOH was 1∶30(w/v).The solution were heated to 50℃ and treated with 400W ultrasonic for 50min.The deposit was collected after centrifugation and washed and re-centrifuged,and then was extracted with 2% acetic acid for 12h at 95℃.Chitosan solu-tion was obtained,and then neutralized by alkali and precipitated.The yield of chitosan was 16.5% after vacuum drying,which was improved com-pared to that before optimization.",
        "keywords": [
            "ultrasonic extraction",
            "Mucor racemosus",
            "chitosan"
        ],
        "authors": [
            {
                "name": "WU Jianguo",
                "org": "Yancheng College of Textile Technology,Yancheng ,China"
            },
            {
                "name": "WANG Lan",
                "org": "Yancheng College of Textile Technology,Yancheng ,China;School of Food Science & Technology,Jiangnan University,Wuxi ,China"
            }
        ],
        "venue": "China Brewing",
        "year": 2011
    },
    "kAHp4JGm": {
        "id": "kAHp4JGm",
        "title": "NS3 protein of hepatitis C virus regulates cyclooxygenase-2 expression through multiple signaling pathways.",
        "abstract": "Hepatitis C virus (HCV) causes chronic hepatitis, which often results in the development of liver cirrhosis and hepatocellular carcinoma (HCC) worldwide. In this study, we demonstrated that the non-structural protein NS3 of HCV enhances cyclooxygenase-2 (COX-2) gene promoter activity, COX-2 mRNA expression, COX-2 protein production, and prostaglandin E2 (PGE2) release in HepG2 cells in a concentration-dependent fashion. We also showed that transcription factor NF-kappaB is required for the activation of COX-2 regulated by NS3. In addition, multiple signaling pathways are involved cooperatively in the expression of COX-2 activated by the viral protein in a calcium-independent manner, which requires signaling components including JNK, ERK, and PKD2. A thorough investigation of mechanism involved in the activation of COX-2 regulated by HCV would provide insights into our understanding the processes of liver inflammatory response and hepatocellular carcinoma development caused by the viral infection and also into the development of novel therapeutics against HCV infection.",
        "keywords": [
            "ns3 protein",
            "signaling pathway",
            "pathogenesis",
            "virus infection",
            "pkc",
            "cyclooxygenase-2",
            "erk",
            "hepatitis c virus",
            "jnk",
            "gene regulation",
            "inflammation"
        ],
        "authors": [
            {
                "name": "Lili Lu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Liang Wei",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Guiqing Peng",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Kailang Wu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Lei Kang",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Xiaohong Yan",
                "org": "The State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2008
    },
    "dybLeR0S": {
        "id": "dybLeR0S",
        "title": "Effects of Changing in Precipitation and Temperature on the Photosynthesis and Related Physiological Parameters of Straw-Yellow Gentian",
        "abstract": "The effects of changing in temperature and precipitation on the photosynthesis or related physiological parameters of straw-yellow gentian(Gentiana straminea Maxim.) were analyzed by changing precipitation and adjusting temperature with LI-6400 portable photosynthesis system.The results showed that the net photosynthetic rate,stomata conductance,intercellular CO2 concentration,transpiration rate of straw-yellow gentian were the highest under increasing precipitation treatments,while water use efficiency(WUE) of straw-yellow gentian were the lowest under increasing precipitation treatments,and they were highest under decreasing precipitation treatments,and there were no significant differences between 25℃ and 15℃.Additionally,the results also showed that the net photosynthetic rate of straw-yellow gentian increased with increasing the photosynthetic active radiation(PAR) when the PAR ranged from 0~800 μmol·m-2·s-1,and it reached maximum when the PAR ranged from 800~1200μmol·m-2·s-1,while it did not change when the PAR ranged from 1200~3000μmol·m-2·s-1.The stomata conductance or transpiration rate of straw-yellow gentian increased with increasing the PAR.The intercellular CO2 concentration of straw-yellow gentian decreased with increasing PAR when the PAR ranged from 0~800μmol·m-2·s-1,while it did not change when the PAR ranged from 800~3000μmol·m-2·s-1.The WUE of straw-yellow gentian increased with increasing the PAR when the PAR ranged from 0~800μmol·m-2·s-1,while it did not change when the PAR ranged from 800~3000μmol·m-2·s-1.The results indicated that decreasing precipitation would low the net photosynthesis rate and related physiological parameters of straw-yellow gentian.",
        "keywords": [
            "Alpine meadows",
            "Photosynthesis",
            "Qinghai-Tibet Plateau",
            "Precipitation and temperature change",
            "Straw-Yellow Gentian"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Grassland",
        "year": 2010
    },
    "tBkJOQsC": {
        "id": "tBkJOQsC",
        "title": "Analysis of genetic effects and heritabilities for linoleic andα-linolenic acid content ofBrassica napus L. across Chinese environments",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Haizhen Zhang",
                "org": ""
            },
            {
                "name": "Chunhai Shi",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Yuling Ren",
                "org": ""
            },
            {
                "name": "Changtao Li",
                "org": ""
            },
            {
                "name": "Dongqing Zhang",
                "org": ""
            },
            {
                "name": "Yaofeng Zhang",
                "org": ""
            }
        ],
        "venue": "European Journal of Lipid Science and Technology",
        "year": 2004
    },
    "HY33MFKG": {
        "id": "HY33MFKG",
        "title": "Corrigendum to “Ethanol Extract from Ampelopsis sinica Root Exerts Anti-Hepatitis B Virus Activity via Inhibition of p53 Pathway In Vitro”",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ran pang",
                "org": ""
            },
            {
                "name": "junyan tao",
                "org": ""
            },
            {
                "name": "shuling zhang",
                "org": ""
            },
            {
                "name": "keli chen",
                "org": ""
            },
            {
                "name": "lei zhao",
                "org": ""
            },
            {
                "name": "xin yue",
                "org": ""
            },
            {
                "name": "yuefeng wang",
                "org": ""
            },
            {
                "name": "pian ye",
                "org": ""
            },
            {
                "name": "jihua dong",
                "org": ""
            },
            {
                "name": "ying zhu",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            }
        ],
        "venue": "Evidence-based Complementary and Alternative Medicine",
        "year": 2015
    },
    "RHmJ7Szu": {
        "id": "RHmJ7Szu",
        "title": "Urban heat island mitigation strategies and lizard thermal ecology: landscaping can quadruple potential activity time in an arid city",
        "abstract": "A global warming of 2 °C is predicted to drive almost half the world’s lizard populations to extinction. Urban heat island (UHI) effects may further exacerbate the impacts of climate change on organisms that are sensitive to small changes in temperature. Currently, the Phoenix metropolitan region in Arizona, USA, is an average of 3 °C warmer than the surrounding desert. With continuing urbanization and climate change, thermal stress will become an increasingly important facet of urban ecology in coming decades. The main objective of our study was to investigate which landscaping styles and microhabitat variables can most effectively reduce the surface temperatures experienced by lizards. Using a bare lot as a control, we placed copper lizard models with data loggers in several vegetation and irrigation treatments that represent the dominant backyard landscaping styles in Phoenix (grassy mesic with mist irrigation, drip irrigated xeric, unirrigated native, and a hybrid style known as oasis). Our lizard models recorded 6915 estimates of potential body temperatures. We show that lizard activity time in summer was restricted to a few hours in un-irrigated native desert landscaping, while heavily irrigated grass and shade trees allowed for continual activity during even the hottest days. Shade, humidity, and sky view factor explained the majority of variation in temperature at a sub-meter scale. We suggest that maintaining the existing diversity of landscaping styles (as part of an ongoing UHI mitigation strategy targeted at humans) will be beneficial for lizards.",
        "keywords": [
            "Landscaping",
            " Lizards",
            " Urban heat island",
            " Thermal ecology",
            " Ectotherms",
            " Body temperature",
            " Reptiles"
        ],
        "authors": [
            {
                "name": "jeffrey w ackley",
                "org": "arizona state university"
            },
            {
                "name": "j michael angilletta",
                "org": "arizona state university"
            },
            {
                "name": "dale f denardo",
                "org": "arizona state university"
            },
            {
                "name": "brian k sullivan",
                "org": "arizona state university"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            }
        ],
        "venue": "Urban Ecosystems",
        "year": 2015
    },
    "swgE35G8": {
        "id": "swgE35G8",
        "title": "P2.11-18 Circulating Serum KLK5 and L1CAM Levels Potentially Predict Clinical Outcome to Anlotinib Therapy in NSCLC Patients",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "J. Lu",
                "org": ""
            },
            {
                "name": "Q. Shi",
                "org": ""
            },
            {
                "name": "L. Zhang",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "B. Zhang",
                "org": ""
            },
            {
                "name": "S. Wang",
                "org": ""
            },
            {
                "name": "X. Zhao",
                "org": ""
            },
            {
                "name": "B. Han",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2019
    },
    "eFJnoRyn": {
        "id": "eFJnoRyn",
        "title": "Research and Improvement of Cricket Indoor Location System",
        "abstract": "At present,people 's demand for the indoor positioning and navigation is getting greater and greater.For example,in some indoor places like exhibition hall,library,torehouse,upermarket,ustomers expect to make use of the equipment for free indoor positioning and navigation.Thus,the purpose of this paper is to introduce the working principle,advantage and disadvantage of Cricket location system based on ultrasonic technology and RFID technology.The way of the improvement of this system has also been brought up.By the way of introducing energy-saving system,allotment of signal channel of Cricket location system will be improved and get the result of the energy consumption and the cost of Cricket positioning system,which will finally reduce the energy consumption and the cost of Cricket indoor positioning system and make sure of the equality among the node.",
        "keywords": [
            "RFID",
            "ultrasonic technology",
            "Cricket location system",
            "channel assigned",
            "indoor location"
        ],
        "authors": [
            {
                "name": "LIU Jun",
                "org": "Ministry of Education Key Laboratory of Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Ministry of Education Key Laboratory of Computing & Signal Processing,Anhui University,Hefei ,China;Computer Science and Technical Institute,Anhui University,Hefei ,China"
            },
            {
                "name": "CHU Xi-dan",
                "org": "Ministry of Education Key Laboratory of Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHU Li-jin",
                "org": "Ministry of Education Key Laboratory of Computing & Signal Processing,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Ministry of Education Key Laboratory of Computing & Signal Processing,Anhui University,Hefei ,China;Computer Science and Technical Institute,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2011
    },
    "oAnGB9Kq": {
        "id": "oAnGB9Kq",
        "title": "Spike protein of SARS-CoV stimulates cyclooxygenase-2 expression via both calcium-dependent and calciumin-dependent protein kinase C pathways",
        "abstract": "We have previously shown that the nucleocapsid protein of SARS-associated coronavirus (SARS-CoV) activated cyclooxygenase-2 (COX-2) expression. In this study, we identified another viral protein, the spike of SARS-CoV, which played an important role in virus-stimulated COX-2 expression after screening all genes from the SARS-CoV genome. We found that an upstream calcium-dependent PKC isozyme PKC alpha that modulates the downstream ERK/NF-kappaB pathway through an influx of extracellular Ca2+ is induced by the spike protein of SARS-CoV. The ERK/NF-kappaB was identified to be involved in the activation of COX-2 promoter and production of COX-2 protein in HEK293T cells. We also demonstrated that another unusual pathway, the calcium-independent PI3K/PKC epsilon/JNK/CREB pathway, functioned in cooperation with the calcium-dependent pathway to induce COX-2 expression upon stimulation by spike protein. This pathway can be blocked by PKC epsilon-specific, small interfering RNA, PI3K/JNK kinase-specific inhibitors as well as dominant negative JNK. PKC epsilon-specific siRNA also attenuated the phosphorylation of JNK. Our results provide evidence that helps us understand the function of SRAS-CoV spike protein in SARS pathogenesis.",
        "keywords": [
            "COX",
            "SARS-CoV",
            "Spike protein",
            "Transcriptional activation"
        ],
        "authors": [
            {
                "name": "Mo Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yongbo Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Chunfang Gu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yinpu Yue",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Kenneth K Wu",
                "org": "University of Texas Health Science Center at Houston(University of Texas),Houston,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
        "year": 2007
    },
    "7igF0jWv": {
        "id": "7igF0jWv",
        "title": "The Relationship between Habitat Loss and Fragmentation during Urbanization: An Empirical Evaluation from 16 World Cities.",
        "abstract": "Urbanization results in habitat loss and habitat fragmentation concurrently, both influencing biodiversity and ecological processes. To evaluate these impacts, it is important to understand the relationships between habitat loss and habitat fragmentation per se (HLHF) during urbanization. The objectives of this study were two-fold: 1) to quantify the different forms of the HLHF relationship during urbanization using multiple landscape metrics, and 2) to test the validity of the HLHF relations reported in the literature. Our analysis was based on a long-term urbanization dataset (1800-2000) of 16 large cities from around the world. Habitat area was represented as the percentage of non-built-up area in the landscape, while habitat fragmentation was measured using several landscape metrics. Our results show that the relationship between habitat loss and habitat fragmentation during urbanization is commonly monotonic-linear, exponential, or logarithmic, indicating that the degree of habitat fragmentation per se increases with habitat loss in general. We compared our results with 14 hypothesized HLHF relationships based on simulated landscapes found in the literature, and found that four of them were consistent with those of urbanization, whereas the other ten were not. Also, we identified six new HLHF relationships when fragmentation was measured by total core area, normalized total core area, patch density, edge density and landscape shape index, respectively. In addition, our study demonstrated that the \"space-for-time\" approach, frequently used in ecology and geography, generated specious HLHF relationships, suggesting that this approach is largely inappropriate for analyses of urban landscapes that are highly heterogeneous in space and unusually contingent in dynamics. Our results show both generalities and idiosyncrasies of the HLHF relationship, providing new insights for assessing ecological effects of urbanization.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, People's Republic of China."
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, People's Republic of China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, People's Republic of China."
            }
        ],
        "venue": "PloS one",
        "year": 2016
    },
    "y5t6pQVc": {
        "id": "y5t6pQVc",
        "title": "Island biogeography of soil bacteria and fungi: similar patterns, but different mechanisms.",
        "abstract": "Microbes, similar to plants and animals, exhibit biogeographic patterns. However, in contrast with the considerable knowledge on the island biogeography of higher organisms, we know little about the distribution of microorganisms within and among islands. Here, we explored insular soil bacterial and fungal biogeography and underlying mechanisms, using soil microbiota from a group of land-bridge islands as a model system. Similar to island species-area relationships observed for many macroorganisms, both island-scale bacterial and fungal diversity increased with island area; neither diversity, however, was affected by island isolation. By contrast, bacterial and fungal communities exhibited strikingly different assembly patterns within islands. The loss of bacterial diversity on smaller islands was driven primarily by the systematic decline of diversity within samples, whereas the loss of fungal diversity on smaller islands was driven primarily by the homogenization of community composition among samples. Lower soil moisture limited within-sample bacterial diversity, whereas smaller spatial distances among samples restricted among-sample fungal diversity, on smaller islands. These results indicate that among-island differences in habitat quality generate the bacterial island species-area relationship, whereas within-island dispersal limitation generates the fungal island species-area relationship. Together, our study suggests that different mechanisms underlie similar island biogeography patterns of soil bacteria and fungi.",
        "keywords": "",
        "authors": [
            {
                "name": "Shao-Peng Li",
                "org": "Institute of Eco-Chongming (IEC), Shanghai, 202162, China."
            },
            {
                "name": "Pandeng Wang",
                "org": "School of Life Sciences & School of Ecology, Sun Yat-sen University, Guangzhou, 510275, China."
            },
            {
                "name": "Yongjian Chen",
                "org": "School of Life Sciences & School of Ecology, Sun Yat-sen University, Guangzhou, 510275, China."
            },
            {
                "name": "Maxwell C Wilson",
                "org": "School of Life Sciences & School of Sustainability, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Xian Yang",
                "org": "School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA."
            },
            {
                "name": "Chao Ma",
                "org": "Anhui Province Key Lab of Farmland Ecological Conservation and Pollution Prevention, School of Resources and Enviro\\nment, Anhui Agricultural University, Hefei, 230036, China."
            },
            {
                "name": "Jianbo Lu",
                "org": "College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, 310036, China."
            },
            {
                "name": "Xiao-Yong Chen",
                "org": "Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences & School of Sustainability, Arizona State University, Tempe, AZ, 85287, USA."
            },
            {
                "name": "Wen-Sheng Shu",
                "org": "School of Life Sciences, South China Normal University, Guangzhou, 510631, China. shuws@mail.sysu.edu.cn."
            },
            {
                "name": "Lin Jiang",
                "org": "School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, 30332, USA. lin.jiang@biology.gatech.edu."
            }
        ],
        "venue": "The ISME journal",
        "year": 2020
    },
    "3dSI8B4k": {
        "id": "3dSI8B4k",
        "title": "Development Situation of the Production of Chitosan by Fermentation",
        "abstract": "The development situations of the production of Chitosan by various fermentation methods were introduced.And deacetylation of chitin as well as methods of extracting chitosan were reviewed.Present situation and perspectives of chitosan were discussed.",
        "keywords": [
            "chitin",
            "separation",
            "fermentation",
            "chitosan"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Sichuan University of Science & Engineering Bio-engineering Department, Zigong ,China"
            },
            {
                "name": "LIU Qing-bin",
                "org": "Sichuan University of Science & Engineering Bio-engineering Department, Zigong ,China"
            },
            {
                "name": "GAN Guang-dong",
                "org": "Sichuan University of Science & Engineering Bio-engineering Department, Zigong ,China"
            }
        ],
        "venue": "Biotechnology",
        "year": 2008
    },
    "Am2VqOyi": {
        "id": "Am2VqOyi",
        "title": "Analysis of embryo, cytoplasmic and maternal correlations for quality traits of rapeseed (Brassica napus L.) across environments",
        "abstract": "derived at maturity from eight plants in the middle part of each plot. Samples of F1 seeds analysed were obtained by using the method of isolated pollination during the flower- ing season. Fatty acids—palmitic acid content (PAC), oleic acid content (OAC), linoleic acid content (LAC), linolenic acid content (LLAC), eicosenoic acid content (EIAC) and erucic acid content (EAC)—were determined (%) by gas chromatography (Zhou and Liu 1987) on a Shimadzu GC- 9A. Glucosinolate content (GSLC; µmol/g), oil content (OC; %) and protein content (PC; %) were also determined by near-infrared reflectance spectroscopy using a NIRSystems model 5000 monochromator (Shenk and Westerhaus 1993), for which about 3 g of each intact sample was scanned in a small ring cup of 36 mm inner diameter. Since the performance of rapeseed quality traits could be simultaneously controlled by different genetic systems, including diploid embryo, cytoplasm and diploid maternal plant, the genotypic correlation among these seed-quality traits may be further partitioned into different components, including embryo additive and dominance correlations, cyto- plasmic correlation, maternal additive and dominance corre- lations, and their G × E interaction correlations. The pheno- typic correlation (rP = CP/ VP(X)VP(Y)) and genotypic cor- relation (rG = CG/ VG(X)VG(Y)) components among seed- quality traits were estimated by using the genetic model for quantitative traits of the diploid plant (Zhu 1992; Zhu and Weir 1994). rG was further partitioned into (i) ge- netic main correlation (rGM = CGM/ VGM(X)VGM(Y) ) compo- nents, including embryo additive (r A = CA/ VA(X)VA(Y)) and dominance (rD = CD/ VD(X)VD(Y)) correlations, cy- toplasmic correlation (rC = CC/ VC(X)VC(Y)), and mater- nal additive (rAm = CAm/ VAm(X)VAm(Y)) and dominance (rDm = CDm/ VDm(X)VDm(Y)) correlations; and (ii) G × E in- teraction correlation (rGE = CGE/ VGE(X)VGE(Y)), including embryo additive (rAE = CAE/ VAE(X)VAE(Y)) and dominance",
        "keywords": [
            "brassica napus l.",
            "genetic main correlations",
            "genotype x environment interaction correlations",
            "nutrient quality",
            "rapeseed",
            "fatty acid",
            "seasonality",
            "genetics",
            "quantitative trait",
            "genotype environment interaction",
            "gas chromatography",
            "embryos"
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "HaiZhen Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Journal of Genetics",
        "year": 2006
    },
    "bVaIgfiD": {
        "id": "bVaIgfiD",
        "title": "On The Narrative Means of Sexual relations of The Romance of The Yang Family",
        "abstract": "The Romance of the Yang Family published in Wanli 34 of Ming Dynasty showed an uncommon narrative means from the combination of Family history with the historical themes.In order to relax the war tension,it put skillfully the narrative means of gifted scholars into the historical narrative pattern,with describing the love stories of the brothers of Yang Family in the battles,so as to make up on distinctive pattern of \"Hero+Handsome\".The perfect combination of \"The royal military officers with chivalrous girls\" broke the deadlock in which historical fictions couldn't link with human life stories and constructed a new fiction state.",
        "keywords": [
            "narrative means of sexual relations",
            "The Romance of the Yang Family",
            "the happy marriage taking place on the battle horse back"
        ],
        "authors": [
            {
                "name": "Gong Shu",
                "org": "Hunan Normal University,changsha "
            },
            {
                "name": "Wu Jian-guo",
                "org": "Hunan Normal University,changsha "
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2008
    },
    "GVFtq8bU": {
        "id": "GVFtq8bU",
        "title": "How can landscape ecology contribute to sustainability science",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Paul Opdam",
                "org": "Wageningen University and Research"
            },
            {
                "name": "Sandra Luque",
                "org": "IRSTEA – UMR TETIS Territoires, Environnement, Télédétection ET Information Spatiale"
            },
            {
                "name": "Joan Iverson Nassauer",
                "org": "University of Michigan"
            },
            {
                "name": "Peter H. Verburg",
                "org": "Vrije Universiteit Amsterdam"
            },
            {
                "name": "Jianguo Wu",
                "org": "Julie A. Wrigley Global Institute of Sustainability, Arizona State University"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2018
    },
    "iPUbnZFe": {
        "id": "iPUbnZFe",
        "title": "Potential effects of climate change on the distributions of Yunnan snub-nosed monkey(Pygathrix Bieti) in China",
        "abstract": "It is crucial to understand rationally the effects of climate change on the distribution of animal species for the biodiversity conservation under the climate change.The effects of climate change on the distribution of Yunnan snub-nosed monkey(Pygathrix Bieti)in China were analyzed by the classification and regression tree(CART)niche model and climate change scenarios of A1,A2,B1 and B2.The results show that the current suitable distribution ranges of Yunnan snub-nosed monkey would decrease under climate change.However,the new distribution region and total distribution region of the monkey would increase,especially in the period of 1991-2020,and then they would decrease from the period of 1991-2020 to the period of 2081-2100.The changes are obvious under scenario A1 of climate changes,and are not obvious under scenario B1 of climate changes.Additionally,the northeast and south ranges of current distribution regions of Yunnan snub-nosed monkey will reduce,while new regions will expand towards west and northwest and southeast of current distribution region with climate changes.The changes of the current distribution regions,new distribution regions and total distribution regions of Yunnan snub-nosed monkey are all negative correlations with annual mean air temperature and annual precipitation in China.The current distribution,new distribution and total distribution regions of the monkey all decrease with the increase of annual mean air temperature and annual precipitation in China by multi-regressive analysis,and the effects of annual mean air temperature in China are larger than that of annual precipitation in China.Thus,climate changes in China will decrease the current distribution regions of Yunnan snub-nosed monkey and increase the expanding distribution regions in the near future,while the new expanding distribution regions and total distribution regions of Yunnan snub-nosed monkey will decrease with the increase of climate change intensity.",
        "keywords": [
            "Climate change scenario",
            "Yunnan snub-nosed monkey(Pygathrix Bieti)",
            "Potential effect",
            "Climatic variable simulation"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "LV Jia-jia",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Meteorology and Environment",
        "year": 2009
    },
    "jnCNFaol": {
        "id": "jnCNFaol",
        "title": "Study on developing calibration models of fat acid composition in intact rapeseed by near infrared reflectance spectroscopy",
        "abstract": "Four hundred ninety seven rapeseed samples, which feature multi-year, multi-loci and highly variant characteristics, were collected as a raw set. The NIR spectra were pretreated by scatter correction and mathematics treatments, and calibration models of fat acid composition of intact rapeseed were developed by using the algorithm method of modified partial least square (MPLS). Meanwhile, three types of sample cups with different capacity were used to screen the suitable calibration model for rapeseed quality breeding. The results showed that the calibration model of 8-gram-sample was the best, and the calibration determination coefficient was in the range of 0.74-0.98. The calibration effects of 3-gram-sample, which were similar to those of 0.6-gram-sample, were good with high determination coefficient (RSQ1, 1-VR) and low error (SEC, SECV). Therefore, the calibration set with multi-year and multi-loci samples can improve the accuracy and repeatability of NIRS models. The fat acids NIRS models of intact rapeseed developed could be introduced into breeding lines' selection, mutant screening and germplasm evaluation.",
        "keywords": [
            "Calibration model",
            "Fat acid",
            "Near infrared reflectance spectroscopy (NIRS)",
            "Rapeseed"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chun-Hai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Hai-Zhen Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Guang Pu Xue Yu Guang Pu Fen Xi/Spectroscopy and Spectral Analysis",
        "year": 2006
    },
    "EH4sYauG": {
        "id": "EH4sYauG",
        "title": "Application and Method for Linear Projective Non-negative Matrix Factorization",
        "abstract": "To solve the problem that the iterative method for Linear Projection-Based Non-negative Matrix Factorization(LPBNMF)is complex,a method,called Linear Projective Non-negative Matrix Factorization(LP-NMF),was proposed.In LP-NMF,from projection and linear transformation angle,an objective function of Frobenius norm is considered.The Taylor series expansion is used.An iterative algorithm for basis matrix and linear transformation matrix is derived strictly and a proof of algorithm convergence is provided.Experimental results show that the algorithm is convergent,and relative to Non-negative Matrix Factorization(NMF)and so on,the orthogonality and the sparseness of the basis matrix are better,in face recognition,there is higher recognition accuracy.The method for LP-NMF is effective.",
        "keywords": [
            "Projective non-negative matrix factorization",
            "Linear transformation",
            "Face recognition"
        ],
        "authors": [
            {
                "name": "HU Li-rui",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "WANG Lei",
                "org": ""
            }
        ],
        "venue": "Computer Science",
        "year": 2013
    },
    "awrzC3iK": {
        "id": "awrzC3iK",
        "title": "A Novel Segmentation Framework Using Sparse Random Feature in Histology Images of Colon Cancer.",
        "abstract": "In this paper, we present a novel segmentation framework for glandular structures in Hematoxylin and Eosin stained histology images, choosing poorly differentiated colon tissue as an example. The proposed framework’ target is to identify precise epithelial nuclei objects. We start with staining separate to detect all nuclei objects, and deploy multi-resolution morphology operation to map the initial epithelial nuclei positions. We proposed a new bag of words scheme using sparse random feature to classify epithelial nuclei and stroma nuclei objects to adjust the rest nuclei positions. Finally, we can use the boundary of optimized epithelial nuclei objects to segment the glandular structure.",
        "keywords": "",
        "authors": [
            {
                "name": "Kun Zhang",
                "org": ""
            },
            {
                "name": "Huiyu Zhou",
                "org": ""
            },
            {
                "name": "Li Chen",
                "org": "Nantong University"
            },
            {
                "name": "Minrui Fei",
                "org": "Shanghai University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Nantong University"
            },
            {
                "name": "Peijian Zhang",
                "org": "Nantong University"
            }
        ],
        "venue": "LSMS/ICSEE",
        "year": 2017
    },
    "53rzmczK": {
        "id": "53rzmczK",
        "title": "Optimization of DSC Experimental Conditions and Correlation Analysis for Gelatinization Temperature Traits of Rice",
        "abstract": "Differential Scanning Calorimetry(DSC) is currently the most accurate method for testing the gelatinization temperature(GT) of rice flour.However,three important factors,including rice flour weight with water volume and the speed of temperature rise in DSC,were differently used in many experiments.Orthogonal design was introduced in present experiment to determine the best conditions for the smallest relative standard deviation(RSD) of TAQ20 DSC.The results indicated that the GT measurements could be influenced by these three important DSC conditions.The combination of 14 μL distilled water with 3.0 mg rice flour and 10 ℃/min speed of temperature rise was the best DSC experimental condition because of the smallest RSD of the GT in each experiment combination.21 indica rice flour samples were used for analyzing GT by this best DSC condition,and their alkali spreading value(ASV) and amylose content(AC) were also determined.The results also showed that the correlation coefficients between GT and ASV or AC were-0.75*** or 0.51* respectively,which meant that GT was significantly negative correlated with ASV,but positive with AC.",
        "keywords": [
            "gelatinization temperature",
            "differential scanning calorimeter",
            "rice",
            "orthogonal design",
            "rice flour"
        ],
        "authors": [
            {
                "name": "Zhang Dapeng",
                "org": "College of Agriculture & Biotechnology,Zhejiang University,Hangzhou "
            },
            {
                "name": "Wu Jianguo",
                "org": "College of Agriculture & Biotechnology,Zhejiang University,Hangzhou "
            },
            {
                "name": "Shi Chunhai",
                "org": "College of Agriculture & Biotechnology,Zhejiang University,Hangzhou "
            }
        ],
        "venue": "Journal of the Chinese Cereals and Oils Association",
        "year": 2011
    },
    "qKTmDjzV": {
        "id": "qKTmDjzV",
        "title": "Characterization of enterovirus 71 infection and associated outbreak of Hand, Foot, and Mouth Disease in Shawo of China in 2012",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Michelle Y. Liu",
                "org": ""
            },
            {
                "name": "Jin Liu",
                "org": ""
            },
            {
                "name": "Weijian Lai",
                "org": ""
            },
            {
                "name": "Jun Luo",
                "org": ""
            },
            {
                "name": "Yingle Liu",
                "org": ""
            },
            {
                "name": "Gia-Phong Vu",
                "org": ""
            },
            {
                "name": "Zhu Yang",
                "org": ""
            },
            {
                "name": "Phong Trang",
                "org": ""
            },
            {
                "name": "Hongjian Li",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "GCW967OQ": {
        "id": "GCW967OQ",
        "title": "Regeneration in gap models: priority issues for studying forest responses to global change",
        "abstract": "",
        "keywords": [
            "climate sensitivity",
            "climate change"
        ],
        "authors": [
            {
                "name": "d t price",
                "org": "natural resources canada"
            },
            {
                "name": "n e zimmerman",
                "org": ""
            },
            {
                "name": "p j van der meer",
                "org": ""
            },
            {
                "name": "manfred j lexer",
                "org": "university of agricultural sciences dharwad"
            },
            {
                "name": "paul w leadley",
                "org": "university of paris sud"
            },
            {
                "name": "i t m jorritsma",
                "org": ""
            },
            {
                "name": "jorg schaber",
                "org": "potsdam institute for climate impact research"
            },
            {
                "name": "d f clark",
                "org": "university of virginia"
            },
            {
                "name": "petra lasch",
                "org": "potsdam institute for climate impact research"
            },
            {
                "name": "steven g mcnulty",
                "org": "united states department of agriculture"
            },
            {
                "name": "j wu",
                "org": "arizona state university at the west campus"
            },
            {
                "name": "benjamin smith",
                "org": ""
            }
        ],
        "venue": "Climatic Change",
        "year": 2001
    },
    "nlvPDGPX": {
        "id": "nlvPDGPX",
        "title": "Activation of the Ras/Raf/MEK pathway facilitates HCV replication via attenuation of the IFN-JAK-STAT pathway",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qi zhang",
                "org": ""
            },
            {
                "name": "rui gong",
                "org": ""
            },
            {
                "name": "jing qu",
                "org": ""
            },
            {
                "name": "yijing zhou",
                "org": ""
            },
            {
                "name": "weiyong liu",
                "org": ""
            },
            {
                "name": "mingzhou chen",
                "org": ""
            },
            {
                "name": "yingle liu",
                "org": ""
            },
            {
                "name": "ying zhu",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            }
        ],
        "venue": "Journal of Virology",
        "year": 2011
    },
    "JlTpxyvz": {
        "id": "JlTpxyvz",
        "title": "Inhibition of hepatitis B virus gene expression and replication by ribonuclease P.",
        "abstract": "Nucleic acid-based gene interfering approaches, such as those mediated by RNA interference and RNase P-associated external guide sequence (EGS), have emerged as promising antiviral strategies. The RNase P-based technology is unique, because a custom-designed EGS can bind to any complementary mRNA sequence and recruit intracellular RNase P for specific degradation of the target mRNA. In this study, a functional EGS was constructed to target hepatitis B virus (HBV) essential transcripts. Furthermore, an attenuated Salmonella strain was constructed and used for delivery of anti-HBV EGS in cells and in mice. Substantial reduction in the levels of HBV gene expression and viral DNA was detected in cells treated with the Salmonella vector carrying the functional EGS construct. Furthermore, oral inoculation of Salmonella carrying the EGS construct led to an inhibition of ~95% in the levels of HBV gene expression and a reduction of ~200,000-fold in viral DNA level in the livers and sera of the treated mice transfected with a HBV plasmid. Our results suggest that EGSs are effective in inhibiting HBV replication in cultured cells and mammalian livers, and demonstrate the use of Salmonella-mediated delivery of EGS as a promising therapeutic approach for human diseases including HBV infection.",
        "keywords": [
            "mt",
            " INSERT KEY WORDS HERE",
            " pharmacology"
        ],
        "authors": [
            {
                "name": "Chuan Xia",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yuan-Chuan Chen",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Hao Gong",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Wenbo Zeng",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Gia-Phong Vu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Phong Trang",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Sangwei Lu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fenyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Molecular therapy : the journal of the American Society of Gene Therapy",
        "year": 2013
    },
    "zdRO5Z33": {
        "id": "zdRO5Z33",
        "title": "An Novel Quality Classification for Ring Die Pellet",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "kun zhang",
                "org": "shanghai university"
            },
            {
                "name": "minrui fei",
                "org": "shanghai university"
            },
            {
                "name": "jianguo wu",
                "org": "nantong university"
            },
            {
                "name": "peijian zhang",
                "org": "nantong university"
            }
        ],
        "venue": "international conference on intelligent computing",
        "year": 2014
    },
    "yUUZCyYf": {
        "id": "yUUZCyYf",
        "title": "Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.",
        "abstract": "Using an in vitro selection procedure, we have previously isolated RNase P ribozyme variants that efficiently cleave an mRNA sequence in vitro. In this study, a variant was used to target the HIV RNA sequence in the tat region. The variant cleaved the tat RNA sequence in vitro about 20 times more efficiently than the wild type ribozyme. Our results provide the first direct evidence that combined mutations at nucleotide 83 and 340 of RNase P catalytic RNA from Escherichia coli (G(83) -> U(83) and G(340) -> A(340)) increase the overall efficiency of the ribozyme in cleaving an HIV RNA sequence. Moreover, the variant is more effective in reducing HIV-1 p24 expression and intracellular viral RNA level in cells than the wild type ribozyme. A reduction of about 90% in viral RNA level and a reduction of 150 fold in viral growth were observed in cells that expressed the variant, while a reduction of less than 10% was observed in cells that either did not express the ribozyme or produced a catalytically inactive ribozyme mutant. Thus, engineered ribozyme variants are effective in inhibiting HIV infection. These results also demonstrate the potential of engineering RNase P ribozymes for anti-HIV application.",
        "keywords": [
            "physics",
            "engineering",
            "ribonuclease p",
            "virus replication",
            "medicine",
            "chemistry",
            "biology"
        ],
        "authors": [
            {
                "name": "Wenbo Zeng",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yuan-Chuan Chen",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Yong Bai",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Phong Trang",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Gia-Phong Vu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Sangwei Lu",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fenyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "PloS one",
        "year": 2012
    },
    "WA9XOpba": {
        "id": "WA9XOpba",
        "title": "Application of Artificial Neural Networks in Time Series Prediction",
        "abstract": "The basic concept and various models of Time Series Prediction are briefly introduced,the methods for Time Series Prediction based on artificial neural network(ANN) are analyzed.In addition the basic principles of BP neural network is explained and a BP neural network based time series prediction method is proposed.Practical example analysis shows that it is feasible to use BP neural network in the prediction of nonlinear time series.Therefore,the neural network prediction can be successfully used in analyzing and predicting the time series variable.",
        "keywords": [
            "MATLAB",
            "artificial neural network(ANN)",
            "time series prediction"
        ],
        "authors": [
            {
                "name": "Xu Pengfei",
                "org": "College of Computer Science & Technology,Anhui University"
            },
            {
                "name": "Li Wei",
                "org": "College of Computer Science & Technology,Anhui University"
            },
            {
                "name": "Zheng Hua",
                "org": "College of Computer Science & Technology,Anhui University"
            },
            {
                "name": "Wu Jianguo",
                "org": "College of Computer Science & Technology,Anhui University"
            }
        ],
        "venue": "Electronic Technology",
        "year": 2010
    },
    "kuyVOCFc": {
        "id": "kuyVOCFc",
        "title": "Research advance in seed germination of desert woody plants]",
        "abstract": "This paper reviewed the research methods of desert woody plants seed germination, and the effects of internal and external ecological factors on it. Most researchers use incubator and artificial climate chamber to dispose the seeds, while field investigation was few involved. Seed dormancy is the important physiological factor affecting germination, while seed size, mass and color are closely correlated with its maturity and vigor. The poor permeability of seed capsule is a barrier that restrains the germination, which can be weakened or eliminated by shaving, cutting, treating with low temperature, and dipping in chemical reagent, etc. Seed water content has a close correlation with its storage life and water-absorbing capability. Suitable temperature is the prerequisite of seed germination, while changing temperature can accelerate the germination. Soil moisture content is a limiting factor, while illumination is not so essential to the seed germination of most desert woody plants. Sand-burying plays an important role in the seed germination through regulating illumination, temperature, and soil moisture content. Salinity stress restrains the seed germination of desert woody plants observably. In further studies, the effects of multi-factors and the eco-physiological and molecular biological mechanisms of germination should be more concerned.",
        "keywords": [
            "affecting factor.",
            "desert ecosystem",
            "seed germination",
            "woody plant"
        ],
        "authors": [
            {
                "name": "Wei Chang",
                "org": "Key Laboratory for Silviculture and Conservation of Education Ministry, Beijing Forestry University, Beijing , China;Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "Jian-guo Wu",
                "org": "Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "Yan-hong Liu",
                "org": "Key Laboratory for Silviculture and Conservation of Education Ministry, Beijing Forestry University, Beijing , China"
            }
        ],
        "venue": "Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban",
        "year": 2007
    },
    "wewHvpCa": {
        "id": "wewHvpCa",
        "title": "An accurate quantitative method for screening effective siRNA probes targeting a Hepatitis B virus transcript in single living cells.",
        "abstract": "A dual fluorescence reporter plasmid expressing EGFP and DsRed-Monomer from separate promoters was constructed for quantitative flow cytometry analysis. Cloning the hepatitis B virus (HBV) X gene into the 3' UTR region of DsRed-Monomer allowed quantifying the efficacy of ten siRNAs designed according to the accessibility of HBx mRNA measured in vitro. Using EGFP as an internal control, a justified calculation of the changed mean fluorescence intensity of DsRed-Monomer in each transfected cell yielded highly consistent results, and revealed all 10 siRNAs achieved over 50% inhibition among which a super effective siRNA achieved 88% inhibition at a very low concentration (0.33 microg/ml). This provides a quantification method critical for therapeutic application of siRNA.",
        "keywords": [
            "dual fluorescence reporter",
            "qffc",
            "quantitative fluorescence flow cytometry assay",
            "hepatitis b virus x protein",
            "quantitative flow cytometry",
            "sirna",
            "hepatitis b virus",
            "internal control",
            "quantitative method",
            "flow cytometry"
        ],
        "authors": [
            {
                "name": "Wen-Ping Tong",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Yu Zhou",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Xinxin Wang",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Fan Yang",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Kai-Lang Wu",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and Department of Biotechnology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China"
            },
            {
                "name": "Yi Zhang",
                "org": ""
            }
        ],
        "venue": "Biochemical and biophysical research communications",
        "year": 2008
    },
    "ohGjo9nd": {
        "id": "ohGjo9nd",
        "title": "The Investigation of Rapid Identification of Suspected Fuel Oil",
        "abstract": "In order to maintain orders in import crude oil market of our country and to solve identification problems,this paper proposes a rapid and accurate identification methodology of import crude oil and fuel oil.The testing method is easy to implement and its results are accurate and reliable,which can provide technical support and legal basis to Customs,inspection and quarantine facilities.",
        "keywords": [
            "Rapid Identification",
            "Fuel Oil"
        ],
        "authors": [
            {
                "name": "Man Qingxiang",
                "org": "Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian,Liaoning,"
            },
            {
                "name": "Ouyang Changjun",
                "org": "Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian,Liaoning,"
            },
            {
                "name": "Wu Jianguo",
                "org": "Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian,Liaoning,"
            },
            {
                "name": "Sun Yanwei",
                "org": "Liaoning Entry-Exit Inspection and Quarantine Bureau,Dalian,Liaoning,"
            }
        ],
        "venue": "Journal of Inspection and Quarantine",
        "year": 2012
    },
    "qGNAD5R5": {
        "id": "qGNAD5R5",
        "title": "COMPARISON OF DETERMINING METHODS OF THE CONTENT OF ISOFLAVONOIDS IN RESIDUE OF PUERARIAE ROOT",
        "abstract": "Four spectrophotometric methods of determining the content of isoflavonoids in residue of radices pueraria were compared with the result of RP-High Performance Liquid Chromatography(RP-HPLC).It was found that the method of Al3+ chelating reaction-spectrophotometry with the astragaloside as the standard sample and 479nm as the test wave was the best,which could be used as a substitution of RT-HPLC when determining the content of isoflavonoids in radices pueraria,and was easy-operated and low-cost.",
        "keywords": [
            "spectrophotometry",
            "residue of radices pueraria",
            "RP-HPLC",
            "isoflavonoids"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "JIA Wei-yan",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "TAN Fang-zhi",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZHU Zhi-guang",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "HU Yang",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Journal of Henan University of Technology(Natural Science Edition)",
        "year": 2007
    },
    "UkuDNyZV": {
        "id": "UkuDNyZV",
        "title": "The Responses of Soil C and N,Microbial Biomass C or N under Alpine Meadow of Qinghai-Tibet Plateau to the Change of Temperature and Precipitation",
        "abstract": "To know the effects of climate change on the soil organic carbon and total nitrogen content,the field controlling experiments of temperature and precipitation manipulation were constructed to analyze the responses of soil C or N,and microbial biomass C or N under alpine meadow to change of temperature and precipitation.The results showed that the change of precipitation would not cause a reducing in soil organic carbon(SOC)content under alpine meadows significantly(P >0.05),while increasing temperature and no changing precipitation would cause decreasing in SOC content at surface soil layer,while increasing temperature and reducing precipitation would cause an increasing in total soil nitrogen content at deep soil layer,while increasing temperature and precipitation would cause a decreasing in total soil nitrogen content.Additionally,the change of precipitation or temperature would not cause a reducing of soil microbial biomass C or N content under alpine meadows significantly,while increasing temperature and reducing precipitation would cause total soil microbial biomass C ratio increasing,and increasing or decreasing precipitation would cause soil microbial biomass N ratio at soil layer increasing.The results indicated that the responses of soil C and N,microbial biomass C or N under alpine meadow to the change of temperature and precipitation were influenced by interaction between temperature and precipitation change or soil depth,and the effects of changing in temperature and soil water was not significantly.",
        "keywords": [
            "soil nitrogen",
            "soil organic carbon",
            "soil microbial biomass",
            "alpine meadow",
            "climate change"
        ],
        "authors": [
            {
                "name": "Heng Tao",
                "org": "School of geographical sciences,Southwest University,Chongqing ;Chinese Academy of Environmental Science,Beijing "
            },
            {
                "name": "Wu Jianguo",
                "org": "Chinese Academy of Environmental Science,Beijing "
            },
            {
                "name": "Xie Shiyou",
                "org": "School of geographical sciences,Southwest University,Chongqing "
            },
            {
                "name": "Wu Meixiang",
                "org": "School of geographical sciences,Southwest University,Chongqing ;Chinese Academy of Environmental Science,Beijing "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2011
    },
    "HHezkPLw": {
        "id": "HHezkPLw",
        "title": "Pycnogenol(®) treatment inhibits bone mineral density loss and trabecular deterioration in ovariectomized rats.",
        "abstract": "Pycnogenol(®) (40 mg/kg) can inhibit aggravated bone resorption, prevent BMD loss, and restore the impaired trabecular microarchitecture in OVX rats after 9-week-intervention.",
        "keywords": [
            "Pycnogenol®",
            "bone mineral density",
            "bone turnover biomarkers",
            "histomorphometry",
            "ovariectomy",
            "oxidative stress"
        ],
        "authors": [
            {
                "name": "Gangyong Huang",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Siqun Wang",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Yibing Wei",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Feiyan Chen",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Jie Chen",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Jingsheng Shi",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            },
            {
                "name": "Jun Xia",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University Shanghai 200040."
            }
        ],
        "venue": "International journal of clinical and experimental medicine",
        "year": 2015
    },
    "DxTE8R2C": {
        "id": "DxTE8R2C",
        "title": "An Investigative View of the Communion between Wang Ran-Ming and Some Talented Female in the Late Ming Dynasty",
        "abstract": "Wang Ran-ming has highly reputation in Late Ming dynasty,who is called romantic and refined foretype.He contacts many talented female,including Liu Ru-shi,Wang Xiu-wei,Lin Tian-su,Yang Yun-you,Huang Yuan-jie,Wu Shan and so on.He tries his best to help them and obtains 'knight' honor so that some literature also describe him.",
        "keywords": [
            "talented female group",
            "Wang Ran-ming",
            "romantic and refined foretype",
            "communion",
            "knight"
        ],
        "authors": [
            {
                "name": "Wu Jian-guo",
                "org": "Liberal Arts College of Hunan Normal University,Changsha, Department of Chinese Language and Literature,Peking University,Beijing 10087"
            },
            {
                "name": "Fu Xiang-long",
                "org": "Liberal Arts College of Hunan Normal University,Changsha, Department of Chinese Language and Literature,Peking University,Beijing 10087"
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2010
    },
    "3zPxkmFp": {
        "id": "3zPxkmFp",
        "title": "Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.",
        "abstract": "Enterovirus 71 (EV71) infection causes hand, foot, and mouth disease (HFMD), and even fatal neurological complications. However, the mechanisms underlying EV71 neurological pathogeneses are largely unknown. This study reveals a distinct mechanism by which EV71 induces apoptosis and autophagy in neural cells. EV71 non-structure protein 3D (also known as RNA-dependent RNA polymerase, RdRp) interacts with the peroxisomal protein acyl-CoA oxidase 1 (ACOX1), and contributes to ACOX1 downregulation. Further studies demonstrate that EV71 reduces peroxisome numbers. Additionally, knockdown of ACOX1 or peroxin 19 (PEX19) induces apoptosis and autophagy in neural cells including human neuroblastoma (SK-N-SH) cells and human astrocytoma (U251) cells, and EV71 infection induces neural cell death through attenuating ACOX1 production. Moreover, EV71 infection and ACOX1 knockdown facilitate reactive oxygen species (ROS) production and attenuate the  pathway , which collectively result in ROS accumulation in neural cells. In conclusion, EV71 downregulates ACOX1 protein expression, reduces peroxisome numbers, enhances ROS generation, and attenuates the /NRF2/HO-1 pathway, thereby inducing apoptosis and autophagy in neural cells. These findings provide new insights into the mechanism underlying EV71-induced neural pathogenesis, and suggest potential treatments for EV71-associated diseases.",
        "keywords": [
            "Hand foot and mouth disease (HFMD)",
            "acyl-CoA oxidase 1 (ACOX1)",
            "enterovirus 71 (EV71)",
            "neurological pathogenesis",
            "peroxisome",
            "reactive oxygen species (ROS)"
        ],
        "authors": [
            {
                "name": "Lei You",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Zhen Luo",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Wei Xu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangzhou Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            }
        ],
        "venue": "Virulence",
        "year": 2020
    },
    "NEavbPbo": {
        "id": "NEavbPbo",
        "title": "Projecting impacts of climate change on global terrestrial ecoregions",
        "abstract": "Abstract   Terrestrial ecoregions, including critical ecoregions (CEs), vulnerable ecoregions (VEs), and intact ecoregions (IEs) have been used by the World Wildlife Fund (WWF) to classify global biodiversity and are being affected by climate change, which was considered as one of the main threats to biodiversity conservation. However, the impacts of future climate change in shifted means and extremes of temperature, precipitation, and cloud cover under the representative concentration pathways (RCP 2.6, 4.5, and 8.5) on the characteristics of these ecoregions have yet to be fully understood. The present study was designed using a dynamic global vegetation model and both current and future climate scenarios, to investigate the impacts of shifted means and extremes of temperature, precipitation, and cloud cover on five ecological indicators including net primary productivity (NPP), carbon storage, runoff, wildfire risk, and habitat transformation at the ecoregional scale. The analysis was performed for the terrestrial ecoregions as a whole, as well as for specific subsets of CEs, VEs, and IEs. The results showed that future climate scenarios (whether RCP 2.6, 4.5, or 8.5) were estimated to increase the mean NPP, runoff, wildfire risk, and habitat transformation for all ecoregion types, when comparing values for 2071–2100 to the baseline (1971–2000) period. In contrast, the mean carbon storage in the TEWs, VEs, and CEs was estimated to decrease from the baseline to the values under RCP 2.6 and RCP 4.5 and then increase to their largest values under RCP 8.5. The mean carbon storage in the IEs under RCP 8.5 was estimated to remain lower than the baseline period values. Climate change in shifted means and extremes of temperature, precipitation, and cloud cover are generally significant drivers of the variances of NPP, carbon storage, runoff, wildfire risk, and habitat transformation under RCP 2.6, RCP 4.5, and RCP 8.5. The dynamics of the climate change metrics and the five ecological indicators have significant implications for biodiversity conservation in changing climates.",
        "keywords": "",
        "authors": [
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Yupeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Yupeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Peijun Shi",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            }
        ],
        "venue": "Ecological Indicators",
        "year": 2019
    },
    "nAdHxVSc": {
        "id": "nAdHxVSc",
        "title": "Genetic and genotype x environment interaction effects from embryo, endosperm, cytoplasm and maternal plant for rice grain shape traits of indica rice",
        "abstract": "A seed genetic model with embryo, endosperm, cytoplasmic and maternal effects and genotype x environment (GE) interaction effects was used for analyzing ratio of length-to-width (RLW) and ratio of length-to-thickness (RLT) of indica rice (Oryza sativa L.). A factorial mating design in two environments was conducted by including nine cytoplasmic male sterile lines (A) and five restorer lines (R) along with their F1 (A x R), F2, reciprocal RF2 and BC1 (A x F1). RLW and RLT were found to be controlled mainly by genetic main effects, but also by GE interaction effects. Variance of maternal effects was larger than other variance components. Variance due to embryo effects and embryo x environment interaction effects could also significantly affect the rice grain shape traits. The total narrow-sense heritability for RLW and RLT were about 85.6 and 69.9%, respectively, with the general heritabilities being 62.5 and 61.9% and the interaction heritabilities being 23.1 and 7.9%. It was suggested by the predicted genetic effects that Zhexie 2, Xieqingzao and Cezao 2-2 were better than other parents for improving rice grain shape traits. (C) 2000 Elsevier Science B.V.",
        "keywords": [
            "Genetic variances",
            "Heritability",
            "Indica rice",
            "Rice grain shape traits",
            "Seed embryo effect"
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jun Zhu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "LongJiang Fan",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Field Crops Research",
        "year": 2000
    },
    "eQ08TKmB": {
        "id": "eQ08TKmB",
        "title": "Partner of Multimedia Projector",
        "abstract": "Traditional teaching mode is changed by multimedia teaching mode.Teacher uses projector to display course contents rather than use blackboard and chalk.But teacher must operate computer to control display of projection screen and can not depart from computer console table.It results in lack of communication between teacher and students and affects teaching quality.To optimize the multimedia teaching environment one partner of multimedia projector is presented.It can be equipped in multimedia classroom and cooperate with existed projector and computer.Teacher can hold the infrared laser pointer to control projection screen on any position of the classroom by click,double click and right-mouse operation.And compared to the wireless mouse,it is easy to use because it need not plane to move on.Compared to the traditional red laser pointer,it can control projection screen rather than indication,page up and page down.",
        "keywords": [
            "infrared laser pen",
            "projector partner",
            "multimedia teaching"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei,Anhui ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei,Anhui ,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei,Anhui ,China"
            }
        ],
        "venue": "Modern Educational Technology",
        "year": 2011
    },
    "RUmuhM0K": {
        "id": "RUmuhM0K",
        "title": "Impacts of erucic acid and glucosinolate content on genetic relationships between protein content and fatty acids of rape seed across environments",
        "abstract": "Impacts of erucic acid content (EAC) and glucosinolate content (GSLC) on the genetic correlations between protein content\n (PC) and oil content (OC) or PC and fatty acid contents (FAC) in rape seed (Brassica napus L.) was analyzed by using unconditional and conditional methods related to genetic effects from the diploid embryo nuclear\n genes, cytoplasm genes and diploid maternal plant nuclear genes. A diallel mating design in two environments was conducted\n by using eight varieties along with their F1 and F2. It was found that there were significant relationships between PC and EAC or PC and GSLC of rape seed, and the conditional\n analysis method could be used to exclude the influences of EAC or GSLC for further revealing the actual genetic relationships\n between PC and OC or PC and FAC. The results from conditional analysis showed that when PC was conditioned on EAC or GSLC\n the conditional phenotypic and genotypic relationships between PC|EAC and oleic acid content or PC|GSLC and OC were changed\n to significantly positive, while those between PC|EAC and eicosenoic acid content or PC|GSLC and linolenic acid content became\n significantly negative. Thus, the levels of EAC and GSLC of rape seed could affect the correlations between PC and OC or PC\n and FAC. For the conditional genetic relationship analysis of different genetic systems, visible changes were found for many\n genetic correlation components from the embryo, cytoplasm and maternal plant between PC and OC or PC and FAC after eliminating\n the influences of EAC or GSLC, especially for conditional embryo dominance, cytoplasmic, maternal additive main covariances\n and conditional embryo dominance interaction covariance.",
        "keywords": [
            "Rape seed (",
            "Brassica napus",
            "L.)",
            "Genetic correlation",
            "Protein content",
            "Erucic acid content",
            "Glucosinolates",
            "Fatty acids",
            "Quality trait"
        ],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            },
            {
                "name": "Wei-Dong Xu",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            },
            {
                "name": "Qian-Ru Yu",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            },
            {
                "name": "Hai-Zhen Zhang",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            },
            {
                "name": "Zhong-Wei Yang",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou, 310029 Zhejiang, People’s Republic of China"
            }
        ],
        "venue": "Euphytica",
        "year": 2011
    },
    "zV6tIffI": {
        "id": "zV6tIffI",
        "title": "Hepatitis B virus induces a novel inflammation network involving three inflammatory factors, IL-29, IL-8, and cyclooxygenase-2.",
        "abstract": "Chronic inflammation induced by hepatitis B virus (HBV) is a major causative factor associated with the development of cirrhosis and hepatocellular carcinoma. In this study, we investigated the roles of three inflammatory factors, IL-8, IL-29 (or IFN-λ1), and cyclooxygenase-2 (COX-2), in HBV infection. We showed that the expression of IL-29, IL-8, and COX-2 genes was enhanced in HBV-infected patients or in HBV-expressing cells. In HBV-transfected human lymphocytes and hepatocytes, IL-29 activates the production of IL-8, which in turn enhances the expression of COX-2. In addition, COX-2 decreases the production of IL-8, which in turn attenuates the expression of IL-29. Thus, we proposed that HBV infection induces a novel inflammation cytokine network involving three inflammatory factors that regulate each other in the order IL-29/IL-8/COX-2, which involves positive regulation and negative feedback. In addition, we also demonstrated that COX-2 expression activated by IL-8 was mediated through CREB and C/EBP, which maintains the inflammatory environment associated with HBV infection. Finally, we showed that the ERK and the JNK signaling pathways were cooperatively involved in the regulation of COX-2. We also demonstrated that IL-29 inhibits HBV replication and that IL-8 attenuates the expression of IL-10R2 and the anti-HBV activity of IL-29, which favors the establishment of persistent viral infection. These new findings provide insights for our understanding of the mechanism by which inflammatory factors regulate each other in response to HBV infection.",
        "keywords": [],
        "authors": [
            {
                "name": "Yi Yu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Rui Gong",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yongxin Mu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Chengliang Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhichen Sun",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Mingzhou Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of immunology (Baltimore, Md. : 1950)",
        "year": 2011
    },
    "qYcSCTmA": {
        "id": "qYcSCTmA",
        "title": "Perioperative comprehensive pain control strategy of the total knee arthroplasty",
        "abstract": "Objective To investigate the clinical efficacy of a comprehensive pain control protocol for the postoperative pain after total knee Arthroplasty. Methods From Mar 2006 to Jun 2007, The postoperative pain of total knee Arthroplasty was treated with a comprehensive pain control protocol. The protocol encompasses preoperative psychological education and preemptive analgesia with COX-2 inhibitors, intraoperative reduction of surgical trauma and modification of surgical technique, periarticular multimodal analgesic injection, postoperative psychological communication with patients, regular use of COX-2 inhibitors, cold compression and active functional exercise. 60 total-knee arthroplasty patients were enrolled into the trial. They were randomized either to receive a intraoperative periarticular multimodal analgesic injection containing ropivacaine, epimorphine, betamethasone and epinephrine (Group MI) or to receive no injection (Group NMI). Visual analog scores for postoperative pain during rest and activity were recorded. Narcotics consumption and side effects were monitored. Results Group MI had lower visual analog scores for pain during rest and less postoperative narcotics consumption than Group NMI with statistical difference between two groups. Less postoperative activity pain was found in Group MI than that in Group NMI and there was no statistical difference between two groups. Less complications were observed in both groups. ConclusionThe combination of comprehensive pain control protocol and periarticular multimodal analgesic injection are a more effective approach to control the postoperative pain of total-knee arthroplasty and can lead to a quick functional recovery in patients with less complications.",
        "keywords": [
            "replacement",
            "Analgesia",
            "Intraoperative period",
            "knee",
            "Arthroplasty"
        ],
        "authors": [
            {
                "name": "WANG Si-qun",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai , China"
            },
            {
                "name": "XIA Jun",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai , China"
            },
            {
                "name": "WEI Yi-bing",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai , China"
            },
            {
                "name": "WU Jian-guo",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai , China"
            }
        ],
        "venue": "Chinese Journal of Joint Surgery(Electronic Version)",
        "year": 2008
    },
    "cph9TTM6": {
        "id": "cph9TTM6",
        "title": "Analysis and Research Based on Skeleton of Handwritten Chinese Character Algorithms",
        "abstract": "Chinese characters discernment is the hard problem in discernment field,and the thining is the first step to deal with.Studies two of the skeleton algorithm,one is based on principal curve,and the other is Hilditch algorithm which is based on a template.Analysis of two different algorithms for the quality of the image of Chinese characters skeleton extraction.Experiments show that the former's performance well,and be able to fit a variety of poor quality images,but still to be optimization.Although the thining effect of the latter is poor,but the speed is fast.",
        "keywords": [
            "principal curve",
            "Hilditch",
            "skeleton",
            "analysis"
        ],
        "authors": [
            {
                "name": "GUO Xing",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China;School of Software,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China;School of Software,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHANG Yi-chao",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2009
    },
    "EPw9RxWO": {
        "id": "EPw9RxWO",
        "title": "Function of RNA-dependent RNA Polymerase of Influenza A Virus on the Regulation of Viral Genome Replication and Transcription",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "TAO Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan , China"
            },
            {
                "name": "PAN Zi-shu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan , China"
            },
            {
                "name": "WU Jian-guo",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan , China"
            }
        ],
        "venue": "中国病毒学(英文版)",
        "year": 2006
    },
    "0KwrVwg7": {
        "id": "0KwrVwg7",
        "title": "Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.",
        "abstract": "Human immunodeficiency virus TAT plays an important role in the disregulation of cytokine production associated with the neurological disorders that follow HIV infection. IL-1beta is one of the important inflammatory cytokines secreted by immune-activated monocytes/macrophages. Previous reports have shown that extracellular TAT stimulates IL-1beta expression in monocytes/macrophages. However, little is known about the mechanisms and possible TAT-responsive elements within the IL-1beta promoter. The present study shows that TAT increases the production of IL-1beta in human monocytes; PLC-PKC pathway-dependent phosphorylation of p44/42 and JNK MAP kinases participates partially in IL-1beta induction by TAT; specific C/EBP and NF-kappaB transcription factor binding elements within the IL-1beta promoter are involved in TAT regulation of IL-1beta production. This study identifies a signaling mechanism for HIV-1-induced IL-1beta production in human monocytes that may be involved in the neuropathogenesis of HIV-associated dementia.",
        "keywords": [
            "interleukin 1β",
            "protein kinase c",
            "phospholipase c",
            "nf-κb",
            "tat",
            "jnk",
            "hiv",
            "p44/42"
        ],
        "authors": [
            {
                "name": "Yongbo Yang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Yuanan Lu",
                "org": ""
            }
        ],
        "venue": "Journal of medical virology",
        "year": 2010
    },
    "0jJxweO2": {
        "id": "0jJxweO2",
        "title": "Experiences of preventing deep venous thrombosis after total hip arthroplasty",
        "abstract": "Objective To summarize the experiences of preventing deep venous thrombosis(DVT) after total hip arthroplasty(THA).Methods 43 patients(48 hips) recieved careful manipulation,leg elevation,,active exercise,and anticoagulant drug(Fondaparinux) to prevent DVT after THA.Color Doppler Sonography was taken and the results before THA,one week after and 3 months after THA were compared.The situation of the incision was observed also.Results Only one patient got DVT in his calf without symptom.Ecchymoses around the incision were found in two patients.Exudation of the incision was found in one patient and it stopped after discontinuation of Fondaparinux.Conclusions The incidence of DVT after THA may be reduced by the integrated methods.",
        "keywords": [
            "replacement",
            "hip",
            "Venous thrombosis",
            "Arthroplasty"
        ],
        "authors": [
            {
                "name": "WEI Yi-bing",
                "org": ".Orthopaedic Department,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "XIA Jun",
                "org": ".Orthopaedic Department,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "WANG Si-qun",
                "org": ".Orthopaedic Department,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ".Orthopaedic Department,Huashan Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "WEI Li-cheng",
                "org": ".Orthopaedic Department,Huashan Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Joint Surgery(Electronic Edition)",
        "year": 2011
    },
    "rnqxvei3": {
        "id": "rnqxvei3",
        "title": "Probe into the Economic Mathematics Course Reforms",
        "abstract": "Based on the analysis of the problems exsitting in the course of economic mathematics,the paper puts forward the ponderations in economic mathematics course reform and discuss the applied characteristics of the economic mathematics.",
        "keywords": [
            "course",
            "application",
            "model",
            "economic mathematics"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Hunan College of Finance and Economics, Changsha ,China"
            }
        ],
        "venue": "Jilin Normal University Journal (Natural Science Edition)",
        "year": 2005
    },
    "bbx7eBMz": {
        "id": "bbx7eBMz",
        "title": "The mineralization of soil nitrogen and its influenced factors under alpine meadows in Qilian Mountains",
        "abstract": "The alpine meadows soil nitrogen mineralization and its relationship with soil temperature,soil water content,soil depth and altitude in Qilian Mountains were analyzed by soil incubation in an orthogonal experiment.Based on the range of soil nitrogen mineralization,the impacts of soil temperature and soil water content on soil nitrogen mineralization were the highest of the impacts of different factors,while the impacts of altitude,soil depth or interaction between soil temperature and soil water content were the lowest.Based on the range of soil nitrogen mineralization ratios,the impacts of soil temperature and altitude on soil nitrogen mineralization were also the highest impacts,but the impacts of soil water content was relatively lower than the impacts of soil temperature,and that of soil depth was the lowest.The impacts of soil temperature and soil water content on soil nitrogen mineralization were significant at the 10% level,and the impacts of soil temperature were significant at the 5% level.Additionally,the impacts of different factors on the ratio of soil nitrogen mineralization were not significant at the 10% level.At 5%,soil nitrogen mineralization at 35℃ was higher than that at 25,15 and 5℃ and it was also higher at 25℃ than at 5℃,but it was not significantly different between 5 and 15℃ or between 15 and 25℃.At the 10% level,it was higher at 15,25,or 35℃ than at 5℃,and it was also higher at 35℃ than at 15 or 25℃.The difference of soil nitrogen mineralization ratios were not significantly different at the 5% level,but at the 10% level,the soil nitrogen mineralization ratio at 35℃ was higher than at 15℃.The difference of soil nitrogen mineralization and its ratio were not significantly different among different soil water contents,while soil nitrogen mineralization was higher at a water content of 40% than at 60%,and the ratio of soil nitrogen mineralization was lower at a soil water content of 60% than at 40% or 20% at the 10% level.The difference of soil nitrogen mineralization and its ratio among different interactions of soil temperature and soil water content were not significant.The difference of soil nitrogen mineralization was not significant between different altitudes,although the soil nitrogen mineralization ratio was lower at an altitude of 3 800 m than at 3 700,3 600 or 3 500 m at the 5% level.Based on the soil nitrogen mineralization rate,the Q10 ranged from 1 to 3,and it was higher from 5 to 15℃ than at 15 to 25℃ or from 25 to 35℃,which was almost same as from 15 to 25℃ and from 25 to 35℃.Based on the soil nitrogen mineralization rate ratio,Q10 ranged from 0.5 to 2,and it was lower from 5 to 15℃ than from 15 to 25℃ or from 25 to 35℃.It was about 2 from 15 to 25℃ or from 25 to 35℃.The results showed that alpine meadow soil nitrogen would be greatly influenced by soil temperature change.",
        "keywords": [
            "Qilian mountains",
            "mineralization of soil nitrogen",
            "alpine meadows"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "HAN Mei",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "CHANG Wei",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China;School of Resource and Environment,Beijing Forestry University,Beijing ,China"
            },
            {
                "name": "AI Li",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China;School of Civil and Environment Engineering,the Science and Technology University of Beijing,Beijing ,China"
            },
            {
                "name": "CHANG Xue-xiang",
                "org": "Cold and Arid Regions Environmental and Engineering Research Institute,CAS,Lanzhou ,China"
            }
        ],
        "venue": "Acta Prataculturae Sinica",
        "year": 2007
    },
    "qGHgaPgB": {
        "id": "qGHgaPgB",
        "title": "HBx protein induces expression of MIG and increases migration of leukocytes through activation of NF-κB",
        "abstract": "Elevated expression of monokine induced by the interferon-gamma (MIG) has been shown in HBV carriers, and it is involved in the infiltration of inflammatory cells and liver damage after HBV infection. However, the molecular mechanisms by which HBV-induced MIG expression have not been characterized. Our results indicated that HBx protein induced MIG expression in a dose-dependent manner. Such increase was due to the direct binding of NF-kappaB to the MIG promoter. By luciferase, chromatin immunoprecipitation and electrophoretic mobility shift assays, we demonstrated that the NF-kappaB binding site at positions -147 was essential for transcriptional activation of MIG promoter by HBx protein. Chemotaxis assay showed that the up-regulation of MIG protein levels enhanced the migration of peripheral blood lymphocytes (PBLs), and inhibition of NF-kappaB significantly decreased the chemotaxis activity. Our findings provide a new insight into how leukocytes migrate to liver, and disclose a new regulatory mechanism of MIG expression after HBV infection.",
        "keywords": [
            "Promoter",
            "HBx",
            "HBV",
            "Migration",
            "MIG",
            "NF-κB"
        ],
        "authors": [
            {
                "name": "Li-Min Xia",
                "org": "Division of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "Wen-Jie Huang",
                "org": "State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People's Republic of China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "College of Live Science, Wuhan University, Wuhan 430072, Hubei Province, People's Republic of China"
            },
            {
                "name": "Yong-Bo Yang",
                "org": "College of Live Science, Wuhan University, Wuhan 430072, Hubei Province, People's Republic of China"
            },
            {
                "name": "Qiong Zhang",
                "org": "Division of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "Zhen-Zhen Zhou",
                "org": "Division of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "Hui-Fen Zhu",
                "org": "Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "Pin Lei",
                "org": "Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "Guan-Xin Shen",
                "org": "Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, People's Republic of China"
            },
            {
                "name": "De-An Tian",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2009
    },
    "ovGbpnuo": {
        "id": "ovGbpnuo",
        "title": "How do climatic and management factors affect agricultural ecosystem services? A case study in the agro-pastoral transitional zone of northern China.",
        "abstract": "Agricultural ecosystem management needs to ensure food production and minimize soil erosion and nitrogen (N) leaching under climate change and increasingly intensive human activity. Thus, the mechanisms through which climatic and management factors affect crop production, soil erosion, and N leaching must be understood in order to ensure food security and sustainable agricultural development. In this study, we adopted the GIS-based Environmental Policy Integrated Climate (EPIC) model to simulate crop production, soil erosion, and N leaching, and used a partial least squares regression model to evaluate the contributions of climate variables (solar radiation, precipitation, wind speed, relative humidity, and maximum and minimum temperature) and management factors (irrigation, fertilization, and crop cultivation area) on agricultural ecosystem services (AES) in the agro-pastoral transitional zone (APTZ) of northern China. The results indicated that crop production and N leaching markedly increased, whereas soil erosion declined from 1980 to 2010 in the APTZ. Management factors had larger effects on the AES than climate change. Among the climatic variables, daily minimum temperature was the most important contributor to the variations in ecosystem services of wheat, maize, and rice. Spatial changes in the cultivated area most affected crop production, soil erosion, and N leaching for majority of the cultivated areas of the three crops, except for the wheat-cultivated area, where the dominant factor for N leaching was fertilization. Although a tradeoff existed between crop production and negative environmental effects, compromises were possible. These findings provide new insights into the effects of climatic and management factors on AES, and have practical implications for improving crop production while minimizing negative environmental impacts.",
        "keywords": [
            "Adaptation",
            "Crop production",
            "Driving factor",
            "EPIC",
            "N leaching",
            "Soil erosion"
        ],
        "authors": [
            {
                "name": "Jianmin Qiao",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), College of Resources Science &amp; Technology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), College of Resources Science &amp; Technology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), College of Resources Science &amp; Technology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China; School of Life Sciences, School of Sustainability, Arizona State University, Tempe, AZ 85287-4501, USA."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2017
    },
    "wfN9QOu9": {
        "id": "wfN9QOu9",
        "title": "Characterization and fine mapping of the glabrous leaf and hull mutants () in rice ( L.)",
        "abstract": "The glabrous leaf and hull () mutants were isolated from M generation of  cultivar 93-11. These mutants produced smooth leaves and hairless glumes under normal growth conditions. By analyzing through scanning electron microscope, it was revealed that the leaf trichomes, including macro and micro hairs, were deficient in these mutants. Genetic analysis indicated that the mutation was controlled by a single recessive gene. Using nine SSR markers and one InDel marker, the  gene was mapped between RM1200 and RM2010 at the short arm of chromosome 5, which was consistent with the mapping of  in previous studies. To facilitate the map-based cloning of the  gene, 12 new InDel markers were developed. A high-resolution genetic and physical map was constructed by using 1,396 mutant individuals of F mapping population. Finally, the  was fine mapped in 54-kb region containing 10 annotated genes. Cloning and sequencing of the target region from four  mutants (gl1-1, gl1-2, gl1-3 and gl1-4) and four glabrous rice varieties (Jackson, Jefferson, Katy and Lemont) all showed that the same single point mutation (A→T) occurred in the 5′-untranslated region (UTR) of the locus  (corresponding to the 3′-UTR of ). RT-PCR analysis of the locus  revealed that its mRNA expression level was normal in  mutant. RNA secondary structure prediction showed that the single point mutation resulted in a striking RNA conformational change. These results suggest that the single point mutation is most likely responsible for the glabrous leaf and hull phenotypes in rice.",
        "keywords": [
            "gl1",
            "Glabrous leaf and hull",
            "Trichome",
            "Map-based cloning",
            "Rice"
        ],
        "authors": [
            {
                "name": "Wenqiang Li",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Shili Weng",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Dapeng Zhang",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Yujiang Zhang",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Plant Cell Reports",
        "year": 2010
    },
    "qbo7mnVN": {
        "id": "qbo7mnVN",
        "title": "Effects of litter removal on plant species diversity: a case study in tropical Eucalyptus forest ecosystems in South China.",
        "abstract": "The removal of litterfall in the Eucalyptus plantations in South China affected the plant biodiversity in these ecosystems was found based on the field observation and lab analysis. The protection times of species diversity of three Eucalyptus communities were different (Community I with no protection, Community II with 7-year-protection, Community III with 35-year-protection). The total numbers of species in these communities (from Community I to II to III) are 1, 6, and 17 respectively. The results showed that the protection of litterfall from being taken out of the ecosystem is important and can increase plant species diversity. This study combined biomass data, the chemical and physical properties of the soil, and the diversity of microbes in the communities. It is concluded that the mechanism of the effects of litter removal on biodiversity includes three factors: removing the suitable habitat of microbe and animal, decreasing the soil nutrient, and changing the special habitat for the germination and growth of invading plants. These results should have important implications for managing these Eucalyptus forest ecosystems in South China.",
        "keywords": [
            "biodiversity",
            "eucalyptus plantation",
            "litter removal",
            "south china"
        ],
        "authors": [
            {
                "name": "Shao-Lin Peng",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            },
            {
                "name": "Hai Ren",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Arizona State University West(Arizona State University West),Phoenix,United States"
            },
            {
                "name": "Hong-Fang Lu",
                "org": "South China Institute of Botany Chinese Academy of Sciences(South China Institute of Botany,S China Inst.Bot.),Guangzhou,China"
            }
        ],
        "venue": "Journal of environmental sciences (China)",
        "year": 2003
    },
    "OGY10q1r": {
        "id": "OGY10q1r",
        "title": "Historical landscape dynamics of Inner Mongolia: patterns, drivers, and impacts",
        "abstract": "Understanding the causes and consequences of land use and land cover change in drylands is crucial for global sustainability. Inner Mongolia consists of arid and semiarid ecosystems of global importance.",
        "keywords": [
            "Mongolian Plateau",
            " Inner Mongolia",
            " Landscape history",
            " Land use and land cover change",
            " Socioeconomic drivers",
            " Grasslands",
            " Rangeland degradation and sustainability"
        ],
        "authors": [
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "qing zhang",
                "org": "inner mongolia university"
            },
            {
                "name": "ang li",
                "org": "chinese academy of sciences"
            },
            {
                "name": "cunzhu liang",
                "org": "inner mongolia university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "ep9yrFgm": {
        "id": "ep9yrFgm",
        "title": "CXCL12-CXCR4 contributes to the implication of bone marrow in cancer metastasis.",
        "abstract": "The CXCL12-CXCR4 axis is postulated to be a key pathway in the interaction between (cancer) stem cells and their surrounding supportive cells in the (cancer) stem cell niche. As the bone marrow constitutes a unique microenvironment for cancer cells, the CXCL12-CXCR4 axis assists the bone marrow in regulating cancer progression. This interaction can be disrupted by CXCR4 antagonists, and this concept is being used clinically to harvest hematopoietic stem/progenitor cells from the bone marrow. The functions of CXCL12-CXCR4 axis in cancer cell-tumor microenvironment interaction and angiogenesis have been recently studied. This review focuses on how CXCL12-CXCR4 helps the bone marrow in creating a tumor mircoenvironment that results in the cancer metastasis. It also discusses ongoing research regarding the clinical feasibility of CXCR4 inhibitors.",
        "keywords": [
            "cxcr4"
        ],
        "authors": [
            {
                "name": "Jingsheng Shi",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China."
            },
            {
                "name": "Yibing Wei",
                "org": ""
            },
            {
                "name": "Jun Xia",
                "org": ""
            },
            {
                "name": "Siqun Wang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Feiyan Chen",
                "org": ""
            },
            {
                "name": "Gangyong Huang",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            }
        ],
        "venue": "Future oncology (London, England)",
        "year": 2014
    },
    "ExMHQodb": {
        "id": "ExMHQodb",
        "title": "Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection.",
        "abstract": "iNOS plays an important role in mediating inflammation. In this study, we found that iNOS-derived NO was increased 2.4-fold in the serum samples of 101 patients infected with influenza A virus in comparison with samples of 105 healthy individuals. In A549 human lung epithelial cells, infection with influenza A virus or stimulation with poly(I:C)+IFN-gamma resulted in increased mRNA and protein levels of both IL-32 and iNOS, with subsequent release of NO. Over-expression of IL-32 resulted in upregulated iNOS expression with subsequent NO production. Knock down of IL-32 by IL-32-specific siRNA resulted in the inhibition of dsRNA-induced expression of iNOS and NO release, indicating that IL-32 is an upstream regulatory factor of dsRNA-triggered iNOS production. Surprisingly, over-expression of iNOS resulted in the reduction of IL-32 expression, and suppression of iNOS by the selective iNOS inhibitor S-methylisothiourea sulfate stimulated IL-32 expression, indicating that a negative feedback mechanism operates between the iNOS/NO and IL-32 systems. These findings suggest that influenza A virus infection activates IL-32 and iNOS expression by a heretofore unrecognized complex mechanism, in which the two pro-inflammatory factors regulate each other, involving positive and negative feedback regulatory loops.",
        "keywords": [
            "inducible nitric oxide synthase",
            "il-32",
            "influenza virus",
            "gene regulation",
            "inflammation",
            "negative feedback"
        ],
        "authors": [
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Fang Yang",
                "org": ""
            },
            {
                "name": "Yan Liu",
                "org": ""
            },
            {
                "name": "Rui Gong",
                "org": ""
            },
            {
                "name": "Li Liu",
                "org": ""
            },
            {
                "name": "Yong Feng",
                "org": ""
            },
            {
                "name": "Pan Hu",
                "org": ""
            },
            {
                "name": "Wei Sun",
                "org": ""
            },
            {
                "name": "Qian Hao",
                "org": ""
            },
            {
                "name": "Lei Kang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            }
        ],
        "venue": "European journal of immunology",
        "year": 2009
    },
    "m7D3QWl5": {
        "id": "m7D3QWl5",
        "title": "Effects of land use change on the biodiversity",
        "abstract": "Land use change is the important factors which threaten the biodiversity. The general trends of the study of impacts of land use change on the gene diversity, population diversity and ecosystem diversity were reviewed and new developing was also sug-gested. The effects of land use change on the gene diversity involved the fragment of species habitats resulted from the land use change, improving the breed of domestic plants or animals of agriculture and livestock’s farms, and changing habitats condition re-sulted from the land use change. And the most of studies were about the effects of land use change on the reproduction of species. The effects of land use change on the species diversity involved the effects of land use change on the dominance and abundance, interspecies relationship, distribution pattern, invasion of species and extinction of species, and the most of the studies were about the dominance and abundance, while there were few studies about the effects of land use change on the extinction and invasion of spe-cies, and the studies were mainly about the effects of land use change on the species diversity of large animal and plants, while there were few studies about the effects of land use change on the species diversity of microbial and small animal or plants. The effects of land use change on the ecosystem diversity involved the structure and distribution of ecosystems. Additionally, there were few stud-ies comprehensive considering the effects of land use change on the gene diversity, species diversity and ecosystem diversity, and analyzing quantitative the effects of land use change on the biodiversity or predicting the effects of land use change on the biodiver-sity. In future, the gene diversity, species diversity and ecosystem diversity should be considered fully, and the effects and mechanism about the effects of land use change on the biodiversity should be studied, and the effects of land use change on the biodiversity could be predicted.",
        "keywords": [
            "biodiversity",
            "land use change",
            "effects"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "Lv Jiajia",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            }
        ],
        "venue": "Ecology and Environment",
        "year": 2008
    },
    "v8gNTBKy": {
        "id": "v8gNTBKy",
        "title": "The mineralization of soil nitrogen and its motivating factors to the dragon spruce forest and alpine meadows of the Qilian Mountains",
        "abstract": "To understand the effects of varying soil temperature and changing in soil water content on the decomposition of soil nitrogen, an anaerobic incubation experiment with orthogonal experiment in an artificial climatic chamber was conducted to investigate how the mineralization of soil nitrogen of the slopes under the Qilian Mountains forest (dominated by Picea crassifolia) and alpine meadows were affected by temperature, soil water content, soil depth, and mountain altitudes. The results showed that based on the range of soil nitrogen mineralization, the effects of soil depth and interaction between soil water content and temperature on soil nitrogen mineralization were the highest, next was the effects of changing in temperature, and the effects of soil water content on them was the lowest. Based on the range of soil nitrogen mineralization ratio, the effects of soil temperature and interaction between soil water content and temperature on soil nitrogen mineralization ratio were also the highest, next were the effects of changing in soil water content, and the effects of soil depth on them was the lowest. The effects of soil temperature and interaction between soil water content and temperature on soil nitrogen mineralization were significant, while the effects of these factors on the ratio of soil nitrogen mineralization were not significant (P < 0.05). The soil nitrogen mineralization was higher at 35 °C than at 5 °C and 15 °C, while there was not significant difference at 25 °C and 15 °C or 5 °C (P < 0.05). Additionally, the soil nitrogen mineralization ratio was higher at 35 °C than at 15 °C, while there was no significant difference at 15 °C or 25 °C and at 5 °C (P < 0.05). The difference of soil nitrogen mineralization were not significant among different soil water contents, while soil nitrogen mineralization ratio was lower in soil water content of 20% than that in soil water content of 60% (P < 0.05). The soil nitrogen mineralization was lower under mountain forest in altitude of 3 200 m than that under shrub meadows in altitude of 3 500 m, while the difference of soil nitrogen mineralization were not significant among in altitude of 3 600 m, 3 400 m and 3 200 m or between in altitude of 3 500 m and 3 600 m (P < 0.05). The soil nitrogen mineralization was higher in 0 - 15 cm soil depth than in 15 - 35 cm soil depth, while the difference of soil nitrogen mineralization ratio among different soil depth was not significant(P < 0.05). The Q10 ranged from 0.7 to 2.0, and it was lower from 5 °C to 15 °C than that from 15 °C to 25 °C or 25 °C to 35 °C. The results showed that the soil nitrogen mineralization under mountain forest and alpine meadows would be influenced greatly by changing in temperature.",
        "keywords": [
            "Alpine meadows",
            "Mineralization of soil nitrogen",
            "Mountain forest",
            "Qilian Mountains"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            },
            {
                "name": "Wei Chang",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            },
            {
                "name": "Li Ai",
                "org": "Chinese Research Academy of Environmental Sciences(Chinese Research Academy of Environmental Sciences,Chinese Research Academy of Environmental Science),Beijing,China"
            }
        ],
        "venue": "Forest Research",
        "year": 2008
    },
    "i2Jgnsmy": {
        "id": "i2Jgnsmy",
        "title": "STUDY ON THE EPIDEMIC STATUS AND PREVENTION OF MALIGNANCY TUMOR IN JIANGSU PROVINCE",
        "abstract": "Jiangsu province had high incidences and mortalities of malignant tumors in China although the government had taken some measures to prevent and control the malignant tumor.The status of malignant tumors is serious in Jiangsu province,which had brought great disease burden for the residents and society.This article put forward prevention and control strategies for promoting health and reducing the incidence and mortality of malignant tumors in terms of the guidance of health management.",
        "keywords": [
            "Status",
            "Malignancy tumor",
            "Prevention and control"
        ],
        "authors": [
            {
                "name": "WANG Fu-ying",
                "org": "Nanjing Medical Univer-sity,Nanjing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Nanjing Medical Univer-sity,Nanjing ,China"
            },
            {
                "name": "LU Jian-hua",
                "org": "Nanjing Medical Univer-sity,Nanjing ,China"
            }
        ],
        "venue": "Modern Preventive Medicine",
        "year": 2009
    },
    "tD0ayovx": {
        "id": "tD0ayovx",
        "title": "CONCEPTS OF SCALE AND SCALING",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "JIANGUO WU",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability 85287-4501 Tempe AZ USA"
            },
            {
                "name": "HARBIN LI",
                "org": "Center for Forested Wetlands Research USDA Forest Service Southern Research Station 29414 Charleston SC USA"
            }
        ],
        "venue": "",
        "year": 2006
    },
    "yY2oFb3x": {
        "id": "yY2oFb3x",
        "title": "In Memoriam: Orie L. Loucks (1931–2016)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2017
    },
    "RKKVTFGg": {
        "id": "RKKVTFGg",
        "title": "Impacts of landscape changes on local and regional climate: a systematic review",
        "abstract": "Studies have shown that land use and land cover change (LUCC) has myriad impacts on local and regional climate. Synthesizing the recent findings in this field helps advance landscape ecology and sustainability science in the face of climate change. To review and synthesize mesoscale modeling-based studies examining the impact of LUCC on climate, and to identify research gaps and future research directions. We adopted a systematic review procedure to identify and analyze relevant literature obtained from the Web of Science spanning Jan 1990–Nov 2018. The number of publications per year increased from about 5 before 2008 to as large as 25 thereafter. About 60% of the case studies were focused on China and the US. Urbanization and agricultural development exerted a stronger influence on temperature than other LUCC modifications, with temperature changes generally between 1 and 2 °C. The climate effect of forest loss and urbanization illustrated location-dependency, as similar landscape changes in different latitudes showed climate effects of opposite sign. Extensive irrigation and dam construction increased precipitation, while the impact of urbanization and forest cover change on precipitation was inconclusive (positive, neutral, and negative). Understanding landscape and climate change interactions is essential for studying the ecology and sustainability of regional landscapes. Future research needs to: (1) understand climate effects resulting from land management change, (2) investigate climate change impacts on human health as induced or mediated by landscape changes, and (3) develop sustainable landscapes that can mitigate and adapt to climate change.",
        "keywords": [
            "Systematic review",
            " Landscape impacts on climate",
            " Land–atmosphere interactions",
            " Regional climate modeling"
        ],
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Institute of Ecology and Biodiversity, School of Life Sciences, Shandong University, Qingdao, China"
            },
            {
                "name": "Yupeng Liu",
                "org": "Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, China"
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning, Urban Climate Research Center, Arizona State University, Tempe, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2020
    },
    "7EckGGbC": {
        "id": "7EckGGbC",
        "title": "Circadian rhythms of fetal liver transcription persist in the absence of canonical circadian clock gene expression rhythms in vivo.",
        "abstract": "The cellular circadian clock and systemic cues drive rhythmicity in the transcriptome of adult peripheral tissues. However, the oscillating status of the circadian clocks in fetal tissues, and their response to maternal cues, are less clear. Most clock genes do not cycle in fetal livers from mice and rats, although tissue level rhythms rapidly emerge when fetal mouse liver explants are cultured in vitro. Thus, in the fetal mouse liver, the circadian clock does not oscillate at the cellular level (but is induced to oscillate in culture). To gain a comprehensive overview of the clock status in the fetal liver during late gestation, we performed microarray analyses on fetal liver tissues. In the fetal liver we did not observe circadian rhythms of clock gene expression or many other transcripts known to be rhythmically expressed in the adult liver. Nevertheless, JTK_CYCLE analysis identified some transcripts in the fetal liver that were rhythmically expressed, albeit at low amplitudes. Upon data filtering by coefficient of variation, the expression levels for transcripts related to pancreatic exocrine enzymes and zymogen secretion were found to undergo synchronized daily fluctuations at high amplitudes. These results suggest that maternal cues influence the fetal liver, despite the fact that we did not detect circadian rhythms of canonical clock gene expression in the fetal liver. These results raise important questions on the role of the circadian clock, or lack thereof, during ontogeny.",
        "keywords": [
            "engineering",
            "computational biology",
            "medicine",
            "chemistry",
            "physics",
            "biology",
            "gene expression profiling",
            "circadian rhythm",
            "transcriptome",
            "light"
        ],
        "authors": [
            {
                "name": "Chengwei Li",
                "org": "National Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei Province, People's Republic of China."
            },
            {
                "name": "Shuang Yu",
                "org": ""
            },
            {
                "name": "Xiaoling Zhong",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Xiaodong Li",
                "org": ""
            }
        ],
        "venue": "PloS one",
        "year": 2012
    },
    "WQTQcRJ5": {
        "id": "WQTQcRJ5",
        "title": "General memory structure based on input method",
        "abstract": "To design a kind of memory structure to describe the characteristic of increasing decoding which the realization of input method had.The state space is constructed by insertion operation of nodes.All nodes are linked by chains.Traverse algorithm got all possible candidates waiting for later period processing without missing anything.Deletion operation only deleted some related nodes and need not restructure the state space.All operation corresponded with users’ input and state space changed equally.This memory structure manifests its clarity of describing question,convenience of solving problem in such applications as hand-written stroke input method,sentence input method and syllable segmentation.It is general memory structure in input method domain.",
        "keywords": [
            "handwritten stroke input",
            "input method",
            "sentence input",
            "syllable segmentation",
            "memory structure"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "FAN Qing-lin",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Design",
        "year": 2008
    },
    "oeD52Ada": {
        "id": "oeD52Ada",
        "title": "Temporal and spatial patterns of NDVI and their relationship to precipitation in the Loess Plateau of China",
        "abstract": "The relationship between vegetation and precipitation has been studied extensively, but little is known about its mechanistic linkage to agro-ecosystem sustainability. In this study, we used 250 m MODIS NDVI 16-day composite data and precipitation data for the period 2001-2005 to evaluate the connection between vegetation and precipitation in the Jinghe River watershed of the central Loess Plateau, China. A principal component analysis (PCA) was employed to determine the primary feature of vegetation cover. The results indicated that the first two principal components (PC1 and PC2) explained around 89% of total NDVI variances. The spatial distribution of PC1 followed an increasing trend from northwest to southeast, a similar dynamics to the spatial pattern of NDVI, which was determined by the variation of mean annual precipitation in the Jinghe River watershed. Furthermore, PC2 was associated with the spring/summer modes of the annual cycle while their intra-annual variations were largely modified by the regular phonological cycle of the winter wheat-summer fallow cropping practices, a dominant farming practice in severely degraded regions of the Loess Plateau. Winter wheat-summer fallow practice was a dominant factor affecting the precipitation-vegetation relationship. A sharp decrease in vegetation cover after wheat harvesting during the rainy seasons from July to September may be a major cause of extensive soil erosion in this region. Our findings provide new insight into the relationship between vegetation and precipitation which is critical in the restoration of degraded ecosystems and developing appropriate crop rotation systems to achieve a certain amount of agricultural sustainability.",
        "keywords": [
            "loess plateau",
            "spatial pattern",
            "16-day composite data",
            "mean annual precipitation",
            "jinghe river watershed",
            "total ndvi variance",
            "vegetation cover",
            "m modis ndvi",
            "precipitation data",
            "agricultural sustainability",
            "precipitation-vegetation relationship",
            "seasonality",
            "soil erosion",
            "crop rotation",
            "annual cycle",
            "principal component analysis",
            "principal component",
            "sustainability",
            "spatial variation",
            "erosion",
            "rotations",
            "remote sensing",
            "precipitation"
        ],
        "authors": [
            {
                "name": "Tianming Wang",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, & MOE Key Laboratory for Biodiversity Science and Engineering, Beijing Normal University, Beijing, PR China"
            },
            {
                "name": "Xiaojun Kou",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, & MOE Key Laboratory for Biodiversity Science and Engineering, Beijing Normal University, Beijing, PR China"
            },
            {
                "name": "Youcai Xiong",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, & MOE Key Laboratory for Biodiversity Science and Engineering, Beijing Normal University, Beijing, PR China"
            },
            {
                "name": "Pu Mou",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, & MOE Key Laboratory for Biodiversity Science and Engineering, Beijing Normal University, Beijing, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences & Global Institute of Sustainability, Arizona State University, Tempe, AZ, USA"
            },
            {
                "name": "Jianping Ge",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, & MOE Key Laboratory for Biodiversity Science and Engineering, Beijing Normal University, Beijing, PR China"
            }
        ],
        "venue": "International Journal of Remote Sensing",
        "year": 2010
    },
    "9emDHa5z": {
        "id": "9emDHa5z",
        "title": "Determination of Sodium、Iron and Copper content in Anthracene Oil- Atomic absorption spectrometric method",
        "abstract": "The samples were in the crucible,then heated it slowly with softfire and ashed it,after evaporated of most of evaporating matters,put the crucible in the oven and ashed it,then disolved it with HCl solution.Determination fo Sodium,Iron and Copper content in Anthracene Oils with Atomic Absorption Spectrometric Method(Flame Method).The result shows,in the range of 0~5mg/l,the liner relation of the content of Iron and Copper is good,corresponding factor υ=0.999,and its recovery ratio is 93~104%,can make the requirement of the inspection of Import and Export Anthracene Oils.",
        "keywords": [
            "Sodium",
            "crucible",
            "Copper",
            "Atomic absorption spectrometric method",
            "Iron"
        ],
        "authors": [
            {
                "name": "Chen Xin-yue",
                "org": "Technology Centre of Entry-exit Lnspection and Quarantine Bureau of liaoning,Dalian,Liaoning,,China"
            },
            {
                "name": "Wu Jian-guo",
                "org": "Technology Centre of Entry-exit Lnspection and Quarantine Bureau of liaoning,Dalian,Liaoning,,China"
            },
            {
                "name": "Sun Yan-wei",
                "org": "Technology Centre of Entry-exit Lnspection and Quarantine Bureau of liaoning,Dalian,Liaoning,,China"
            },
            {
                "name": "Yu Xiao-zhan",
                "org": "Technology Centre of Entry-exit Lnspection and Quarantine Bureau of liaoning,Dalian,Liaoning,,China"
            },
            {
                "name": "Tian Yuan-hong",
                "org": "Technology Centre of Entry-exit Lnspection and Quarantine Bureau of liaoning,Dalian,Liaoning,,China"
            }
        ],
        "venue": "Fujian Analysis & Testing",
        "year": 2013
    },
    "7nNzOXSc": {
        "id": "7nNzOXSc",
        "title": "Assessing habitat fragmentation’s hierarchical effects on species diversity at multiple scales: the case of Thousand Island Lake, China",
        "abstract": "The study of habitat fragmentation is fraught with definitional and conceptual challenges. Specifically, a multi-scale perspective is needed to address apparent disagreements between landscape- and patch-based studies that have caused significant uncertainty concerning fragmentation’s effects. Here we test the hypothesis that habitat fragmentation alters biological communities by creating hierarchically nested selective pressures across plot-, patch-, and landscape-scales in the Thousand Island Lake, China. We assess the variation in fragmentation-diversity relationships contextualize the interplay of scale-dependent relationships. This work utilized two datasets. At the island scale, islands were sampled to adequately capture the vast majority of species on each island using 5 × 5 m sampling cells. To capture intra-island variation, we sampled 400 m2 plots set up along an edge gradient on each island. The variation in species richness at each scale was then compared using Wilcoxon tests, Spearman rank correlations, generalized linear models, and single-large-or-several-small (SLOSS) simulations. We find that edges have little impact on plot α-diversity and between-plot β-diversity, but increase the amount of β-diversity that can be attributed to nestedness at the plot-scale. We also find that the percent habitat in the surrounding landscape has a positive effect on species richness at the patch-scale and that small islands accumulate species faster than large islands of equal total size at the landscape-scale. By observing interdependent effects at each scale, we find support for the hypothesis that habitat fragmentation’s effects are hierarchically structured. Therefore, multi-scale approaches are needed to understand the patterns, processes, and consequences of fragmentation.",
        "keywords": [
            "Habitat fragmentation",
            " Hierarchical patch dynamics",
            " Species diversity",
            " Thousand Island Lake"
        ],
        "authors": [
            {
                "name": "Maxwell C. Wilson",
                "org": "School of Life Sciences, Arizona State University, Tempe, USA"
            },
            {
                "name": "Guang Hu",
                "org": "Department of Landscape Architecture, School of Civil Engineering and Architecture, Zhejiang Sci-Tech University, Hangzhou, China"
            },
            {
                "name": "Lin Jiang",
                "org": "School of Biological Sciences, Georgia Institute of Technology, Atlanta, USA"
            },
            {
                "name": "Jinliang Liu",
                "org": "College of Life and Environmental Science, Wenzhou University, Wenzhou, China"
            },
            {
                "name": "Jiajia Liu",
                "org": "College of Life Sciences, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Yi Jin",
                "org": "State Key Laboratory of Plant Physiology and Development in Guizhou Province, School of Life Sciences, Guizhou Normal University, Guiyang, China"
            },
            {
                "name": "Mingjian Yu",
                "org": "College of Life Sciences, Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2020
    },
    "2lULYK7j": {
        "id": "2lULYK7j",
        "title": "Three-Gorges Dam--Experiment in Habitat Fragmentation?",
        "abstract": "Habitat fragmentation is the primary cause of the loss of biodiversity and ecosystem services, but its underlying processes and mechanisms remain poorly understood. Studies of islands and insular terrestrial habitats are essential for improving our understanding of habitat fragmentation. We argue that the Three-Gorges Dam, the largest that humans have ever created, presents a unique grand-scale natural experiment that allows ecologists to address a range of critical questions concerning the theory and practice of biodiversity conservation.",
        "keywords": [],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "J. Wu is in the Department of Plant Biology, Arizona State University, Tempe, AZ 85287, USA. E-mail: <span class=\"em-link\"><span class=\"em-addr\">jingle.wu{at}asu.edu</span></span> and ;Guest Professor at the Chinese Academy of Sciences. All other authors are at the Institute of Botany, Chinese Academy of Sciences, Beijing, People's Republic of China."
            },
            {
                "name": "Jianhui Huang",
                "org": "J. Wu is in the Department of Plant Biology, Arizona State University, Tempe, AZ 85287, USA. E-mail: <span class=\"em-link\"><span class=\"em-addr\">jingle.wu{at}asu.edu</span></span> and ;Guest Professor at the Chinese Academy of Sciences. All other authors are at the Institute of Botany, Chinese Academy of Sciences, Beijing, People's Republic of China."
            },
            {
                "name": "Xingguo Han",
                "org": "J. Wu is in the Department of Plant Biology, Arizona State University, Tempe, AZ 85287, USA. E-mail: <span class=\"em-link\"><span class=\"em-addr\">jingle.wu{at}asu.edu</span></span> and ;Guest Professor at the Chinese Academy of Sciences. All other authors are at the Institute of Botany, Chinese Academy of Sciences, Beijing, People's Republic of China."
            },
            {
                "name": "Zongqiang Xie",
                "org": "J. Wu is in the Department of Plant Biology, Arizona State University, Tempe, AZ 85287, USA. E-mail: <span class=\"em-link\"><span class=\"em-addr\">jingle.wu{at}asu.edu</span></span> and ;Guest Professor at the Chinese Academy of Sciences. All other authors are at the Institute of Botany, Chinese Academy of Sciences, Beijing, People's Republic of China."
            },
            {
                "name": "Xianming Gao",
                "org": "J. Wu is in the Department of Plant Biology, Arizona State University, Tempe, AZ 85287, USA. E-mail: <span class=\"em-link\"><span class=\"em-addr\">jingle.wu{at}asu.edu</span></span> and ;Guest Professor at the Chinese Academy of Sciences. All other authors are at the Institute of Botany, Chinese Academy of Sciences, Beijing, People's Republic of China."
            }
        ],
        "venue": "science",
        "year": 2003
    },
    "zMNO1N8q": {
        "id": "zMNO1N8q",
        "title": "A newly-designed positioning system for simultaneous indocyanine green and fluorescein anterior segment angiography of the albino rabbit",
        "abstract": "Background: Simultaneous recording of vertical iris indocyanine green angiography (ICGA) and iris fluorescein sodium angiography (IFA) in albino rabbits. Material/Methods: An easily adjusted control system was designed to position the CSLO scanning lens perpendicular to the surface of the iris. Twelve albino rabbits were randomly divided into 2 groups. Using 5 mg fluorescein sodium and 5 mg indocyanine green, iris angiograms (IA) of 6 albino rabbits were performed with application of the positioning system in Group A, and no positioning system in Group B. The time spending on vertical eye position and the effects of simultaneous IA were observed. Results: With the use of the positioning system, the irises of rabbits quickly achieved the vertical site, averaging 37.50±8.17 s in Group A, and 408.33±58.79s in Group B. The difference was statistically significant, and the time saved averaged 370.83 s. Compared with the other methods of single-dye angiography, simultaneous digital angiography provided 2 kinds of full, dynamic videos of iris vessels in all albino rabbits. The emergence time of IFA and ICGA was 5-9 s, with an average time for ICGA of 6.4 s, and for IFA of 6.5 s. Except for leakage, the simultaneous ICGA and IFA appearance of this vascular pattern was the same as the single IFA described previously. Conclusions: Simultaneous vertical IA with indocyanine green and fluorescein sodium is a potentially powerful technique that allows high-quality fluorescence imaging of the albino rabbit iris. © Med Sci Monit, 2010.",
        "keywords": [
            "Confocal scanning laser ophthalmoscope",
            "Iris angiography",
            "Positioning control system",
            "Rabbit"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Xiaoxu Zhou",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Long Su",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Song Lin",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Guoling Sun",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Luxia Chen",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Longli Zhang",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Xiaorong Li",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2010
    },
    "L0CoRLp7": {
        "id": "L0CoRLp7",
        "title": "Landscape dynamics of medium-and small-sized cities in eastern and western china: A comparative study of pattern and driving forces",
        "abstract": "Urbanization is an important aspect of land use and cover change, which profoundly affects ecosystem composition, structure and function as well as regional landscape pattern and processes. The rapid development of small- and medium-sized cities is a significant characteristic of global urbanization today, and is expected to remain so for decades in the future. During the last 50 years, the fastest growing cities in China are small-and medium-sized cities with populations ≤ 500 thousands. Thus, small-and medium-sized cities are important for regional social development and urbanization, which has significant impacts on the sustainability of the regions and the entire nation. In the past 20 years, because of the rapidly rising number of small-and medium-sized cities, their urbanization effects have received increasing attention. Understanding the generalities and idiosyncrasies of the urbanization patterns and processes of these cities is crucial for sustainable development. However, much of the current research on urbanization has focused primarily on the large cities with populations > 500 thousands. Few studies have investigated the complexity and dynamics of small-and medium-sized cities, including the relationship between urban landscape patterns and urban ecosystem functions. In this study, we selected 24 small-and medium-sized cities in Xinjiang and the Yangtze River Delta region to quantify landscape change and underlying driving forces in the two regions using a comparative approach. Based on the results of our study, we concluded: (1) In the two regions, urban land type had the highest growth rate with a mean annual increase of > 5%, suggesting a rapid urbanization process from 1986 to 2000. However, the specific changes of land use and land cover types differed in the two regions. In the Yangtze River Delta, cropland declined in area significantly more than other types, with a mean annual decrease rate of 62. 87 km2. In the Xinjiang region, the areas of unused land and grassland declined substantially during the study period. The mean annual decrease rates of these two land-use types were 123. 6 km2 and 90. 2 km2, respectively. (2) The overall pattern of landscape change in the two regions was similar during the 15 years. The level of landscape fragmentation, landscape diversity, and patch shape complexity all increased. However, the urban landscape pattern among different cities in the Yangtze River Delta region became more homogeneous compared to the Xinjiang region. (3) Our comparison of the main forces driving landscape change in the two regions indicated that the changes in croplands contributed significantly to the changes in the overall landscape pattern of small-and medium-sized cities. In the Yangtze River Delta, the main driving forces of landscape change were associated with population growth and rural-to-urban migration of people. A large quantity of cropland was used for urban construction and became increasingly fragmented as urbanization unfolded. In contrast, the main driver of landscape change in the Xinjiang region was related predominantly to the increase in croplands due to population growth and immigration. In this case, the increased human activity resulted in the increase in cropland. Urban sprawl contributed relatively less to landscape pattern change in Xinjiang than in the Yangtze River Delta. In addition, the expansion of croplands not only took up a large amount of grassland resources, but also intensified land use on the grasslands, consequently leading to degradation of the grassland ecosystems. These findings provide useful information for dealing with ecological and environmental problems induced by rapid urbanization, and for sustainable development of small-and medium-sized cities in China. Further studies are needed to investigate the processes and mechanisms of how urbanization affects biodiversity and ecosystem services in these small-to medium-sized cities.",
        "keywords": [
            "Driving force",
            "Landscape pattern",
            "Medium-and small-sized cities",
            "Urbanization"
        ],
        "authors": [
            {
                "name": "Yang Qi",
                "org": "China National Environment Monitoring Center(National Environment Monitoring Center,China National Environment Monitoring Center,Environment Monitoring Center of China),Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Jianlong Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yang Yu",
                "org": "China National Environment Monitoring Center(National Environment Monitoring Center,China National Environment Monitoring Center,Environment Monitoring Center of China),Beijing,China"
            },
            {
                "name": "Fuli Peng",
                "org": "China National Environment Monitoring Center(National Environment Monitoring Center,China National Environment Monitoring Center,Environment Monitoring Center of China),Beijing,China"
            },
            {
                "name": "Cong Sun",
                "org": "China National Environment Monitoring Center(National Environment Monitoring Center,China National Environment Monitoring Center,Environment Monitoring Center of China),Beijing,China"
            }
        ],
        "venue": "Shengtai Xuebao/ Acta Ecologica Sinica",
        "year": 2013
    },
    "YPVgEG7M": {
        "id": "YPVgEG7M",
        "title": "The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10.",
        "abstract": "Co-infection with human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) is associated with faster progression of liver disease and an increase in HCV persistence. However, the mechanism by which HIV-1 accelerates the progression of HCV liver disease remains unknown.HIV-1/HCV co-infection is associated with increased expression of interferon gamma-induced protein-10 (IP-10) mRNA in peripheral blood mononuclear cells (PBMCs). HCV RNA levels were higher in PBMCs of patients with HIV-1/HCV co-infection than in patients with HCV mono-infection. HIV-1 Tat and IP-10 activated HCV replication in a time-dependent manner, and HIV-1 Tat induced IP-10 production. In addition, the effect of HIV-1 Tat on HCV replication was blocked by anti-IP-10 monoclonal antibody, demonstrating that the effect of HIV-1 Tat on HCV replication depends on IP-10. Taken together, these results suggest that HIV-1 Tat protein activates HCV replication by upregulating IP-10 production.HIV-1/HCV co-infection is associated with increased expression of IP-10 mRNA and replication of HCV RNA. Furthermore, both HIV-1 Tat and IP-10 activate HCV replication. HIV-1 Tat activates HCV replication by upregulating IP-10 production. These results expand our understanding of HIV-1 in HCV replication and the mechanism involved in the regulation of HCV replication mediated by HIV-1 during co-infection.",
        "keywords": [],
        "authors": [
            {
                "name": "Jing Qu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qi Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Youxing Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Lvxiao Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "BMC immunology",
        "year": 2012
    },
    "qyr11VQk": {
        "id": "qyr11VQk",
        "title": "State space model based on sentence input method",
        "abstract": "This paper realizes sentence input method using state space model which integrates Viterbi algorithm into.State space of sentence conversion is described successfully.In state space model insertion operation only needs produce candidate words related with Pinyin node recently inserted and needs not modify Pinyin node and candidate word nodes before.Deletion operation is very simple;it only needs delete the candidate node produced by this Pinyin node.It can get the best sentence by father pointer of candidate node with the biggest probability which points to the end of Pinyin node chain in right indicator.State space model is easier to judge previous node and subsequent node than word grid and is proved effective in sentence conversion by experiment.",
        "keywords": [
            "state space model",
            "Viterbi algorithm",
            "candidate node",
            "sentence input method"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2008
    },
    "h1ajNTNm": {
        "id": "h1ajNTNm",
        "title": "Speedy method of ballot image recognition",
        "abstract": "To solve the problem of speedy locating and recognition of handwritten character image in voting system,the method of speedy locating and recognition of handwritten character in the video image of paper ballot is proposed based on the design of ballot,which has been taken full account of,and the structure feature of the character.Relevant position data recorded in the design of ballot help to preprocess the ballot image,find a definite reference point,extract the position data in the design of ballot,convert them to an image position data which is connected to the reference point position,then search table lines through the position data,and determine the exact position so as to recognize images.Based on the exact position data,the handwritten character image can be captured and preprocessed.With the selected structure feature,the recognition of handwritten character is realized.High speed of locating and accuracy of recognition in this method have been successfully proved by experiments.",
        "keywords": [
            "handwritten character",
            "video image",
            "structure feature",
            "ballot",
            "image recognition"
        ],
        "authors": [
            {
                "name": "HU Li-rui",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University, Hefei ,China;School of Computer Science and Technology,Nantong University,Nantong ,China;School of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University, Hefei ,China;School of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "GUO Xing",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University, Hefei ,China;School of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Design",
        "year": 2012
    },
    "WLZp0DnH": {
        "id": "WLZp0DnH",
        "title": "Anticancer and anti-angiogenic activities of extract from Actinidia eriantha Benth root.",
        "abstract": "The present research demonstrated that the significant anticancer and anti-angiogenic effects of AER, providing the supportive evidence for its traditional use in the treatment for cancer. It was suggested that AER could be use as a potential source of cancer therapeutic drug.",
        "keywords": [
            "Actinidia eriantha Benth",
            "Anti-angiogenic",
            "Anti-cancer",
            "Chemical components",
            "Root"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, NO.1 Qiuyang Road, Shangjie Town, Minhou County, Fuzhou 350108, PR China. Electronic address: wjg1419@126.com."
            },
            {
                "name": "Li Ma",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, NO.1 Qiuyang Road, Shangjie Town, Minhou County, Fuzhou 350108, PR China. Electronic address: 374579304@qq.com."
            },
            {
                "name": "Shui-Hua Lin",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, NO.1 Qiuyang Road, Shangjie Town, Minhou County, Fuzhou 350108, PR China. Electronic address: 280204099@qq.com."
            },
            {
                "name": "Yan-Bin Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, NO.1 Qiuyang Road, Shangjie Town, Minhou County, Fuzhou 350108, PR China. Electronic address: 122810146@qq.com."
            },
            {
                "name": "Jun Yi",
                "org": "Department of Chemistry and Life Science, Fujian Institute of Education, Fuzhou 350001, PR China. Electronic address: 864741148@qq.com."
            },
            {
                "name": "Bin-Jun Yang",
                "org": "College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, PR China. Electronic address: 845725483@qq.com."
            },
            {
                "name": "Jin-Zhong Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, NO.1 Qiuyang Road, Shangjie Town, Minhou County, Fuzhou 350108, PR China. Electronic address: jinzhongfj@126.com."
            },
            {
                "name": "Ka-Hing Wong",
                "org": "Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, PR China. Electronic address: kahing.wong@polyu.edu.hk."
            }
        ],
        "venue": "Journal of ethnopharmacology",
        "year": 2017
    },
    "76Ejxrzu": {
        "id": "76Ejxrzu",
        "title": "Genetic Analysis for Lysine Content of Rapeseed Cake (Brassic napus L.) at Different Periods after Anthesis",
        "abstract": "Both conditional and unconditional analysis methods were applied to estimate the genetic main effects and the genotype × environment (GE) interaction effects from embryo (cotyledon),cytoplasmic and maternal plant at different periods after anthesis for lysine content of rapeseed cake by using two-year experimental data. Lysine content (LC) in rapeseed cake was simultaneously controlled by the genetic main effects and their GE interaction effects from different genetic systems,especially for the GE interaction effects. Therefore,the expression of genes conferring LC in the different genetic systems could be significantly influenced by the environments. Among the different genetic components,the maternal effects on LC of rapeseed cake were the most important at all periods after anthesis except for the larger embryo main effects at 36 day after flowering,in which both maternal dominance effect and maternal additive interaction effect were more visible. It was found that the new expression of quantitative genes on LC trait was most active at 23–29 days after flowering by using the conditional statistical analysis method. The discontinuity of gene expression in the developmental process of rapeseed was also observed. The total narrow-sense heritability of LC was high,of which the maternal heritability was important at most periods after anthesis. It was suggested that LC could be efficiently improved when selection is based on the holistic performance of maternal plants in generations. The study further suggested that Eyouchangjia and Gaoyou 605 were better than other parents for increasing LC of progenies.",
        "keywords": [
            "Lysine content",
            "Genetic main effects",
            "Developmental genetics",
            "Rapeseed (Brassica napus L.)",
            "Heritability",
            "Genotype × environment interaction effects"
        ],
        "authors": [
            {
                "name": "CHEN Guo-Lin",
                "org": ", 1 College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China; School of Biosystems Engineering and Food Sciences,Zhejiang Forestry University,Lin'an ,China"
            },
            {
                "name": "WU Jian-Guo",
                "org": ", 1 College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "ZHANG Li",
                "org": ", 1 College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "SHI Chun-Hai",
                "org": ", 1 College of Agriculture and Biotechnology,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Acta Agronomica Sinica",
        "year": 2010
    },
    "NQ9a4Go9": {
        "id": "NQ9a4Go9",
        "title": "Urbanization diversifies land surface phenology in arid environments: Interactions among vegetation, climatic variation, and land use pattern in the Phoenix metropolitan region, USA",
        "abstract": "Urbanization transforms vegetation pattern and ecosystem processes which are controlled primarily by climate in desert regions. The objective of this study was to investigate how urbanization affects vegetation phenology and its coupling with climate in the Phoenix metropolitan region, USA. Our analysis of Normalized Difference Vegetation Index (NDVI) time-series reveals a complex pattern of land surface phenology in response to urbanization. Croplands and urbanized areas show growth multimodality, which is usually found in riparian areas of the region but absent in the native desert. Agriculture is characterized by the shortest growth length and fastest greening and senescing rates. Conversely, urban vegetation stays photosynthetically active for longer periods. Desert NDVI is regulated by 3-5 month accumulated precipitation, but riparian vegetation is uncorrelated with rainfall. NDVI spatial patterns are best predicted by climatic variables near the peak of annual growth. Spring and summer NDVI is in better agreement with precipitation accumulated over longer time periods, while early autumn growth is strongly correlated with immediate and one-month rainfall. Temperature correlates negatively with desert but positively with riparian NDVI. Managed vegetation growth is decoupled from precipitation and completely unsynchronized with natural desert vegetation. Overall, urbanization has resulted in a greater phenological diversity that is not in sync with climatic variability. Our findings provide new insights into the interactions among vegetation growth, climate variability, and urbanization in dry lands. © 2011 Elsevier B.V.",
        "keywords": [
            "land surface phenology",
            "modis ndvi",
            "remote sensing",
            "sonoran desert",
            "urban-rural gradient",
            "vegetation phenology"
        ],
        "authors": [
            {
                "name": "Alexander Buyantuyev",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2012
    },
    "kgeqI9sj": {
        "id": "kgeqI9sj",
        "title": "Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA.",
        "abstract": "Viral pathogens are a major threat to rice production worldwide. Although RNA interference (RNAi) is known to mediate antiviral immunity in plant and animal models, the mechanism of antiviral RNAi in rice and other economically important crops is poorly understood. Here, we report that rice resistance to evolutionarily diverse viruses requires Argonaute18 (AGO18). Genetic studies reveal that the antiviral function of AGO18 depends on its activity to sequester microRNA168 (miR168) to alleviate repression of rice AGO1 essential for antiviral RNAi. Expression of miR168-resistant AGO1a in ago18 background rescues or increases rice antiviral activity. Notably, stable transgenic expression of AGO18 confers broad-spectrum virus resistance in rice. Our findings uncover a novel cooperative antiviral activity of two distinct AGO proteins and suggest a new strategy for the control of viral diseases in rice.",
        "keywords": [
            "rnai",
            "infectious disease",
            "microbiology",
            "plant biology",
            "rice",
            "viral disease",
            "viruses"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Zhirui Yang",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Yu Wang",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Lijia Zheng",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Ruiqiang Ye",
                "org": "Tsinghua Univ, Coll Life Sci, Ctr Plant Biol, Tsinghua Peking Ctr Life Sci, Beijing 100084, Peoples R China"
            },
            {
                "name": "Yinghua Ji",
                "org": "Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210014, Jiangsu, Peoples R China"
            },
            {
                "name": "Shanshan Zhao",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Shaoyi Ji",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Ruofei Liu",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Le Xu",
                "org": "Tsinghua Univ, Coll Life Sci, Ctr Plant Biol, Tsinghua Peking Ctr Life Sci, Beijing 100084, Peoples R China"
            },
            {
                "name": "Hong Zheng",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            },
            {
                "name": "Yijun Zhou",
                "org": "Jiangsu Acad Agr Sci, Inst Plant Protect, Nanjing 210014, Jiangsu, Peoples R China"
            },
            {
                "name": "Xin Zhang",
                "org": "Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China"
            },
            {
                "name": "Xiaofeng Cao",
                "org": "Chinese Acad Sci, State Key Lab Plant Genom, Beijing 100101, Peoples R China"
            },
            {
                "name": "Lianhui Xie",
                "org": "Fujian Agr & Forestry Univ, Inst Plant Virol, Fujian Prov Key Lab Plant Virol, Fuzhou 350002, Fujian, Peoples R China"
            },
            {
                "name": "Zujian Wu",
                "org": "Fujian Agr & Forestry Univ, Inst Plant Virol, Fujian Prov Key Lab Plant Virol, Fuzhou 350002, Fujian, Peoples R China"
            },
            {
                "name": "Yijun Qi",
                "org": "Tsinghua Univ, Coll Life Sci, Ctr Plant Biol, Tsinghua Peking Ctr Life Sci, Beijing 100084, Peoples R China"
            },
            {
                "name": "Yi Li",
                "org": "Peking Univ, Coll Life Sci, State Key Lab Prot & Plant Gene Res, Beijing 100871, Peoples R China"
            }
        ],
        "venue": "ELIFE",
        "year": 2015
    },
    "pUPGWOyu": {
        "id": "pUPGWOyu",
        "title": "SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.",
        "abstract": "Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII). EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of HBV replication. This study revealed a distinct mechanism underlying the suppression of EnhII/Cp activation and HBV replication. On the one hand, the sex determining region Y box2 (SOX2), a transcription factor, is induced by HBV. On the other hand, SOX2, in turn, represses the expression levels of HBV RNAs, HBV core-associated DNA, hepatitis B surface antigen (HBsAg), and hepatitis B e antigen (HBeAg), thereby playing an inhibitory role during HBV replication. Further studies indicated that SOX2 bound to the EnhII/Cp DNA and repressed the promoter activation. With the deletion of the high mobility group (HMG) domain, SOX2 loses the ability to repress EnhII/Cp activation, viral RNA transcription, HBV core-associated DNA replication, HBsAg and HBeAg production, as well as fails to enter the nucleus, demonstrating that the HMG domain is required for the SOX2-mediated repression of HBV replication. Moreover, SOX2 represses HBsAg and HBeAg secretion in BALB/c mice sera, and attenuates HBV 3.5kb RNA transcription and hepatitis B virus core protein (HBc) production in the liver tissues, demonstrating that SOX2 suppresses HBV replication in mice. Furthermore, the results revealed that the HMG domain was required for SOX2-mediated repression of HBV replication in the mice. Taken together, the above facts indicate that SOX2 acts as a new host restriction factor to repress HBV replication by binding to the viral EnhII/Cp and inhibiting the promoter activation through the HMG domain.",
        "keywords": [
            "Cp",
            "EnhII",
            "HBV",
            "HBV Enhancer II",
            "HBV core promoter",
            "SOX2",
            "hepatitis B virus",
            "sex determining region Y box2",
            "viral replication"
        ],
        "authors": [
            {
                "name": "Hua Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Jiayin Mo",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Peiyi Zhao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yunting Song",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Ge Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "Department of Clinical Laboratory, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            }
        ],
        "venue": "Viruses",
        "year": 2020
    },
    "ee2RLvkG": {
        "id": "ee2RLvkG",
        "title": "Habitat fragmentation changes top-down and bottom-up controls of food webs.",
        "abstract": "Top-down and bottom-up controls regulate the structure and stability of ecosystems, but their relative roles in terrestrial systems have been debated. Here we studied a hydro-inundated land-bridge system in subtropical China and tested the relative importance of these two controls in determining the rodent-mediated regeneration of a locally dominant tree species. Our results showed that both controls operated in terrestrial habitats and that their relative importance switched as habitat size changed. Habitat loss initially removed predators of rodents that released rodent populations and triggered massive seed predation (top-down control), leading to reduced seedling establishment. A further reduction in habitat size led to decrease in rodent population that was supposed to increase seedling survival of the tree species, but the decline in habitat size deteriorated the abiotic environments (bottom-up control) that severely prevented seedling recruitment. As the ongoing global land use change is creating increasing number of small-sized forest fragments, our findings provide novel insights into the restoration of seriously fragmented forests.",
        "keywords": [
            "Top-down and bottom-up controls",
            "food web structure",
            "habitat fragmentation",
            "habitat loss",
            "land-bridge system",
            "seedling recruitment",
            "subtropical evergreen broadleaved forests"
        ],
        "authors": [
            {
                "name": "Rong Wang",
                "org": "Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China."
            },
            {
                "name": "Xin Zhang",
                "org": "Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, School of Ecological and Environmental Sciences, East China Normal University, Shanghai, 200241, China."
            },
            {
                "name": "Yi-Su Shi",
                "org": "Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, School of Ecological and Environmental Sciences, East China Normal University, Shanghai, 200241, China."
            },
            {
                "name": "Yuan-Yuan Li",
                "org": "Zhejiang Tiantong Forest Ecosystem National Observation and Research Station, School of Ecological and Environmental Sciences, East China Normal University, Shanghai, 200241, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences &, Global Institute of Sustainability, Arizona State University, Tempe, AZ, 85287-4501, USA."
            },
            {
                "name": "Fangliang He",
                "org": "Department of Renewable Resources, University of Alberta, Edmonton, Alberta, T6G 2H1, Canada."
            },
            {
                "name": "Xiao-Yong Chen",
                "org": "Shanghai Institute of Pollution Control and Ecological Security, Shanghai, 200092, China."
            }
        ],
        "venue": "Ecology",
        "year": 2020
    },
    "pbsVagvt": {
        "id": "pbsVagvt",
        "title": "Rescue of wild-type mumps virus from a strain associated with recent outbreaks helps to define the role of the SH ORF in the pathogenesis of mumps virus.",
        "abstract": "Mumps virus (MuV) causes acute infections in humans. In recent years, MuV has caused epidemics among highly vaccinated populations. The largest outbreak in the U.S. in the past 20 years occurred in 2005-2006 with over 5000 reported cases in which the majority of the cases was in vaccinated young adults. We sequenced the complete genome of a representative strain from the epidemic (MuV-IA). MuV-IA is a member of genotype G, the same genotype of MuV that was associated with the outbreak in the UK in 2004-2005. We constructed a reverse genetics system for MuV-IA (rMuV-IA), and rescued a virus lacking the open reading frame (ORF) of the SH gene (rMuV∆SH). rMuV∆SH infection in L929 cells induced increased NF-κB activation, TNF-α production and apoptosis compared to rMuV-IA. rMuV∆SH was attenuated in an animal model. These results indicated that the SH ORF of MuV plays a significant role in interfering with TNF-α signaling and viral pathogenesis during virus infection.",
        "keywords": [
            "apoptosis",
            "attenuation",
            "vaccine",
            "mumps virus",
            "rat brain",
            "tnf-alpha",
            "outbreak",
            "parainfluenza virus 5",
            "paramyxovirus",
            "sh"
        ],
        "authors": [
            {
                "name": "Pei Xu",
                "org": "Intercollege Graduate Program in Cell and Developmental Biology, Pennsylvania State University, University Park, PA 16802, USA"
            },
            {
                "name": "Zhuo Li",
                "org": "Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA 30602, USA"
            },
            {
                "name": "Dengyun Sun",
                "org": "Intercollege Graduate Program in Cell and Developmental Biology, Pennsylvania State University, University Park, PA 16802, USA"
            },
            {
                "name": "Yuan Lin",
                "org": "Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, GA 30602, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Chinese-French Liver Disease Research Institute at Zhongnan Hospital, Wuhan University, Wuhan 430072, P.R. China"
            },
            {
                "name": "Paul A Rota",
                "org": "Centers for Diseases Control and Prevention, Atlanta, GA 30333, USA"
            },
            {
                "name": "Biao He",
                "org": ""
            }
        ],
        "venue": "Virology",
        "year": 2011
    },
    "0y8da23R": {
        "id": "0y8da23R",
        "title": "Diagnostic and prognostic significance of long noncoding RNA SSTR5-AS1 in patients with gastric cancer.",
        "abstract": "Our findings indicate that SSTR5-AS1 served as a promising novel prognostic biomarker for GC.",
        "keywords": "",
        "authors": [
            {
                "name": "Y Cheng",
                "org": "Department of Digestive Diseases, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, Shaanxi, China. shuiquabw1@163.com."
            },
            {
                "name": "J Di",
                "org": ""
            },
            {
                "name": "J Wu",
                "org": ""
            },
            {
                "name": "H-T Shi",
                "org": ""
            },
            {
                "name": "B-C Zou",
                "org": ""
            },
            {
                "name": "Y Zhang",
                "org": ""
            },
            {
                "name": "D-H Xie",
                "org": ""
            }
        ],
        "venue": "European review for medical and pharmacological sciences",
        "year": 2020
    },
    "jYJsG7c4": {
        "id": "jYJsG7c4",
        "title": "Restoration and management of the Inner Mongolia grassland require a sustainable strategy.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Gaoming Jiang",
                "org": ""
            },
            {
                "name": "Xingguo Han",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "AMBIO",
        "year": 2006
    },
    "Xy7Id3rx": {
        "id": "Xy7Id3rx",
        "title": "A Method of Estimate ofγ~2 for the Extrema of Conditional Sample Function",
        "abstract": "Some methods of estimate ofγ~2 in the conditional sample functions are discussed.A new method-bootstrap is putted forward and the properties of the statistics which are obtained from the new method are analyzed.",
        "keywords": [
            "Conditional sample functions",
            "bootstrap",
            "extrema",
            "estimate ofγ~2"
        ],
        "authors": [
            {
                "name": "WU JIANGUO",
                "org": "Department of Mathematics,Hunan College of Finance and Economics,Changsha,"
            }
        ],
        "venue": "Chinese Journal of Applied Probability and Statistics",
        "year": 2009
    },
    "GnAOAgad": {
        "id": "GnAOAgad",
        "title": "Household Transmission of Human Adenovirus Type 55 in Case of Fatal Acute Respiratory Disease.",
        "abstract": "We identified a case of fatal acute respiratory disease from household transmission of human adenovirus type 55 (HAdV-55) in Anhui Province, China. Computed tomography showed severe pneumonia. Comparative genomic analysis of HAdV-55 indicated the virus possibly originated in Shanxi Province, China. More attention should be paid to highly contagious HAdV-55.",
        "keywords": [
            "China",
            "acute respiratory disease",
            "adenoviruses",
            "fatality",
            "household transmission",
            "human adenovirus type 55",
            "viruses"
        ],
        "authors": [
            {
                "name": "Shuping Jing",
                "org": ""
            },
            {
                "name": "Jing Zhang",
                "org": ""
            },
            {
                "name": "Mengchan Cao",
                "org": ""
            },
            {
                "name": "Minhong Liu",
                "org": ""
            },
            {
                "name": "Yuqian Yan",
                "org": ""
            },
            {
                "name": "Shan Zhao",
                "org": ""
            },
            {
                "name": "Na Cao",
                "org": ""
            },
            {
                "name": "Junxian Ou",
                "org": ""
            },
            {
                "name": "Kui Ma",
                "org": ""
            },
            {
                "name": "Xiangran Cai",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ya-Fang Mei",
                "org": ""
            },
            {
                "name": "Qiwei Zhang",
                "org": ""
            }
        ],
        "venue": "Emerging infectious diseases",
        "year": 2019
    },
    "AFSPApTv": {
        "id": "AFSPApTv",
        "title": "Fast prediction model based big data system identification",
        "abstract": "",
        "keywords": [
            "big data"
        ],
        "authors": [
            {
                "name": "kun zhang",
                "org": "shanghai university"
            },
            {
                "name": "jianguo wu",
                "org": "nantong university"
            },
            {
                "name": "minrui fei",
                "org": "shanghai university"
            },
            {
                "name": "peijian zhang",
                "org": "nantong university"
            }
        ],
        "venue": "",
        "year": 2013
    },
    "D7TyxTon": {
        "id": "D7TyxTon",
        "title": "Spatiotemporal patterns and drivers of ecosystem service supply and demand across the conterminous United States: A multiscale analysis.",
        "abstract": "Land-use and land-cover changes associated with urbanization have significantly influenced biodiversity and ecosystem functions, as well as the supply and demand of ecosystem services (ESs). Assessing ESs and exploring their drivers are critical for regional land-use planning and ecological sustainability. In this study, the supply-demand matrix approach was used to quantify ES supply, demand, and their gap at multiple scales across the conterminous United States from 1940 to 2011. A new integrated measurement framework was proposed to offset ES deficits by identifying an optimal land-use conversion strategy. We focused on exploring the scale and spatial effects of the impacts of various drivers on ESs using ordination and regression analysis. The results showed that the expansion of developed land led to decreased ES supply and increased ES demand during the past seven decades, generating growing ES deficits at different scales, especially in highly urbanized metropolitan areas. To alleviate or offset ES deficits, promoting the intensive utilization of developed land and converting cropland, pasture, and barren land into forests would be the optimal land use strategies. Moreover, the drivers of ESs exhibited not only scale dependence but also spatial heterogeneity. The smaller the scale, the more diverse the drivers. The natural and socioeconomic drivers explained less variation at the metropolitan scale than at the state scale. Economic factors were key drivers for ESs at the state scale, while social factors were key drivers at the metropolitan scale. The regression coefficients for the drivers of ESs in the geographically weighted regression (GWR) model showed remarkable spatial heterogeneity. The GWR coefficients might have important implications for decision making in ES management. Localized and efficient land-use strategies and management policies are needed to reduce the ecological footprints of urban areas and thus achieve regional sustainability.",
        "keywords": [
            "Drivers",
            "ES gap",
            "ES supply and demand",
            "Ecosystem services (ESs)",
            "Land-use change",
            "Multiple scales"
        ],
        "authors": [
            {
                "name": "Xiao Sun",
                "org": "Key Laboratory of Agricultural Remote Sensing (AGRIRS), Ministry of Agriculture and Rural Affairs/Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: sunxiao@caas.cn."
            },
            {
                "name": "Huajun Tang",
                "org": "Key Laboratory of Agricultural Remote Sensing (AGRIRS), Ministry of Agriculture and Rural Affairs/Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: tanghuajun@caas.cn."
            },
            {
                "name": "Peng Yang",
                "org": "Key Laboratory of Agricultural Remote Sensing (AGRIRS), Ministry of Agriculture and Rural Affairs/Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: yangpeng@caas.cn."
            },
            {
                "name": "Guang Hu",
                "org": "School of Civil Engineering and Architecture, Zhejiang Sci-Tech University, Hangzhou 310018, China."
            },
            {
                "name": "Zhenhuan Liu",
                "org": "School of Geography and Planning, Sun Yat-Sen University, Guangzhou 510275, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ 85287, USA. Electronic address: Jingle.Wu@asu.edu."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2019
    },
    "YGAJ6mDk": {
        "id": "YGAJ6mDk",
        "title": "SOIL MICROBIAL ACTIVITY AND BIOMASS C AND N CONTENT IN THREE TYPICAL ECOSYSTEMS IN QI LIAN MOUNTAINS,CHINA",
        "abstract": "Aims Our objectives were to measure the soil microbial biomass carbon(SMB C),soil microbial biomass nitrogen(SMB N)content and soil microbial activity,and determine the relationship between these parameters and other soil properties(including organic carbon,total nitrogen content and water content)in montane forest(dominated by Picea crassifolia),steppe and alpine meadow ecosystems in Qi Lian Mountains,China.Methods We measured SMB C and SMB N content using fumigation-incubation method and soil microbial activity using substrate-induced respiration.Important findings The SMB C content under forest was 60% and 120% higher than under steppe and alpine meadow,respectively,and it was 40% higher under steppe than alpine meadow.The SMB N content was 64% and 111% higher in 0-5 cm soil depth under forest than alpine meadow and steppe,respectively,and it was 29% higher under alpine meadow than steppe.Also,it was 7% and 191% higher in 5-15 cm soil depth under forest than steppe and alpine meadow,respectively,and it was 171% higher under steppe than alpine meadow(p<0.05).The ratio SMB C(SMB C-to-SOC(Soil organic carbon),0.4%-2.8%)was 32% higher under forest and steppe than alpine meadow,and the ratio of SMB N(SMB N-to-total soil N,0.5%-2.8%)in 0-5 and 5-15 cm soil depths was 150% higher under forest and steppe than alpine meadow(p<0.05).Soil microbial activity in 0-5 or 5-15 cm soil depth was 26% higher under forest or alpine meadow than steppe,and in 15-35 cm soil depth it was 28% higher under forest than steppe and alpine meadow(p<0.05).The SMB C and SMB N content was positively correlated with SOC content,and the SMB N content or its ratio was also positively correlated with the SMB C content and its ratio(r2>0.30,p<0.000 1).The SMB N content,SMB C ratio,SMB N ratio and microbial activity were significantly negatively correlated with soil pH.The SMB C content,SMB N content and their ratio and microbial activity were positively correlated with soil water content.",
        "keywords": [
            "soil organic carbon",
            "total soil N",
            "soil microbial activity",
            "Qi Lian Mountains",
            "soil microbial biomass C and N"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing,,China,and"
            },
            {
                "name": "AI Li",
                "org": "Chinese Academy of Environmental Sciences,Beijing,,China,and;University of Science and Technology Beijing,Beijing ,China"
            }
        ],
        "venue": "Journal of Plant Ecology",
        "year": 2008
    },
    "po3qDBB1": {
        "id": "po3qDBB1",
        "title": "Partitioning genetic effects due to embryo, cytoplasm and maternal parent for oil content in oilseed rape (Brassica napus L.)",
        "abstract": "",
        "keywords": [
            "breeding selection",
            "environmental interactions",
            "heritability",
            "qtl",
            "embryos"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            },
            {
                "name": "Hai-Zhen Zhang",
                "org": ""
            }
        ],
        "venue": "Genetics and Molecular Biology",
        "year": 2006
    },
    "tdQ1TZ9y": {
        "id": "tdQ1TZ9y",
        "title": "Potential Effect of Climate Change on Distribution  of 6 Desert Animals in China",
        "abstract": "It is crucial to understand the effects of climate change on change of species distribution for the conservation of biodiversity.The effects of climate change on change of distribution of Goitred Gazelle(Gazella subgutturosa reginae adlerberg),Goitred Gazelle(Gazella subgutturosa yarkandensis blanford),Wild Cat(Felis silvestris schreber),Asiatic Wild Ass(Equus hemionus(pallas),Stone Marten(Martes foina(erxleben) and Camelus Bactrianus(Camelus bactrianus linnaeus) in China were analyzed by use of the CART(classification and regression tree) niche model under climate change scenarios of A2 and B2.The results show that climate change will cause decrease in the current distribution region of the animals.In 2081—2100,the decrease of current distribution region of Goitred Gazelle(Gazella subgutturosa reginae adlerberg),Wild Cat or Asiatic Wild Ass was the highest,while the decrease of current distribution region of Goitred Gazelle(gazella subgutturosa yarkandensis blanford),Stone Marten or Camelus Bactrianus was lower than that of Goitred Gazelle,Wild Cat or Asiatic Wild Ass.The new suitable distribution region or total suitable distribution region of Goitred Gazelle(Gazella Subgutturosa Reginae Adlerberg),Stone Marten or Camelus Bactrianus increases from 1991—2020 to 2081—2100,while that of other animals will decrease from 1991—2020 to 2081—2100.Additionally,following climate change,the western or northern or south-eastern regions of current suitable distribution of Asiatic Wild Ass would reduce,and new suitable regions would expand towards north-western Qinghai or western Tibet;and the current suitable distribution regions of Goitred Gazelle(gazella subgutturosa yarkandensis blanford) will be fragmented greatly,and new suitable regions would expand scattered towards west or northern Xinjiang or KunLun Mountains;and south or east or west regions of current suitable distribution of Wild Cat will reduce and fragment,and new suitable regions would expand towards western or northern or southern current distribution of the animals;and south or south-east regions of current suitable distribution of other animals would reduce,while new suitable regions would expand towards west or north-west regions of current distribution of these animals.Additionally,following climate change,the change of suitable distribution region of the animals was not consistently related with change of annual mean air temperature or precipitation in China,and the change in current distribution region,suitable distribution region or total distribution region of many animals was poorly related with change in annual mean air temperature or precipitation in China,and the suitable distribution region of many animals was not linearly changed with change of the annual mean air temperature and precipitation in China,and the determined coefficient of the linear regression correlation between the change of many animals distribution and annual mean air temperature and annual precipitation in China was not high.The results indicate that climate change will cause decrease in the current distribution region of the animals in the future,while it will cause expansion of suitable distribution region or total distribution region of the animals,and it will also cause change in spatial distribution pattern of the animals.",
        "keywords": [
            "spatial distribution pattern",
            "endangered animal",
            "CART model",
            "climate change"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "ZHOU Qiao-fu",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Desert Research",
        "year": 2011
    },
    "oZ9QwGZ8": {
        "id": "oZ9QwGZ8",
        "title": "On Assimilating and Reconstructing of Historians' Value System in The Romance of the Yang Family",
        "abstract": "While practicing the orthodox historians' value system consciously and adopting brotherhood loyalty value concept worshiped by social common customs,The Romance of the Yang Family obviously showed a dual value trend which was different from the early historical romance.Chief officer Yang Liulang's recognition and practice of traditional Confucian moral standards continuously followed the orthodox values concept constructed in The Romance of Three Kingdoms.However,Meng Liang,Jiao Zan and other warrior figures' behavior was affected directly by the value concept of brotherhood loyalty pictured in Heroes of the Marshes.The five generations of the Yang Family depicted obviously a picture showing a combination of the orthodox Confucian culture with loyal brotherhood culture.",
        "keywords": [
            "assimilation",
            "The Romance of the Yang Family",
            "historians' value system",
            "reconstruction"
        ],
        "authors": [
            {
                "name": "GONG Shu",
                "org": "College of Liberal Arts,Hunan Normal University,Changsha,Hunan ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Liberal Arts,Hunan Normal University,Changsha,Hunan ,China"
            }
        ],
        "venue": "Journal of Social Science of Hunan Normal University",
        "year": 2006
    },
    "LRNarusj": {
        "id": "LRNarusj",
        "title": "Genetic analysis for pod weight at different developmental stages in Brassica napus L.",
        "abstract": "Pod weight (PW),an important quantitative trait very closely related to seed yield,was analyzed using conditional and unconditional genetic models to find out the dynamic effects of genes for this trait during rapeseed development,which comprised of pods harvested at 15,22,29,36 and 43 days after flowering and fertilization. For the unconditional analysis,the additive effects were found to be more important at most stages except for the developmental time of 22 day at which the dominant effects were more prominent. For the conditional analysis,16-22 days after flowering was found to be the most active period for dynamic expression of genes related to pod weight as many new genes were expressed during this period. Heritability analysis revealed that selection in early generations could be effective for improving pod weight in oilseed rape breeding. Prediction of genetic effects for oilseed rape parents showed that Double 20-4,Zhong R-888 and Tower could be used for improving PW in oilseed rape breeding,which Zhong R-888 was the best one. The results further indicate that the heterosis over mid-parent value based on population mean at the stages of 16-22 and 23-29 days was significantly larger than those at other stages.",
        "keywords": [
            "heterosis",
            "oilseed rape (Brassica napus L.)",
            "developmental genetics",
            "heritability",
            "pod weight"
        ],
        "authors": [
            {
                "name": "LI Yun-xia",
                "org": "Department of Agronomy,College of Agriculture & Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Department of Agronomy,College of Agriculture & Biotechnology,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "SHI Chun-hai",
                "org": "Department of Agronomy,College of Agriculture & Biotechnology,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Journal of Zhejiang University(Agriculture and Life Sciences)",
        "year": 2009
    },
    "vmykjdOt": {
        "id": "vmykjdOt",
        "title": "Bovine PrP C directly interacts with αB-crystalline",
        "abstract": "",
        "keywords": [
            "yeast two hybrid assay",
            "polyacrylamide gel electrophoresis",
            "cdna library",
            "heat shock protein"
        ],
        "authors": [
            {
                "name": "guihong sun",
                "org": "wuhan university"
            },
            {
                "name": "mingxiong guo",
                "org": "wuhan university"
            },
            {
                "name": "ao shen",
                "org": "wuhan university"
            },
            {
                "name": "fanghua mei",
                "org": "wuhan university"
            },
            {
                "name": "xiaoxue peng",
                "org": "wuhan university"
            },
            {
                "name": "rui gong",
                "org": "wuhan university"
            },
            {
                "name": "deyin guo",
                "org": "wuhan university"
            },
            {
                "name": "jianguo wu",
                "org": "wuhan university"
            },
            {
                "name": "po tien",
                "org": "wuhan university"
            },
            {
                "name": "gengfu xiao",
                "org": "wuhan university"
            }
        ],
        "venue": "FEBS Letters",
        "year": 2005
    },
    "DtdzoPSG": {
        "id": "DtdzoPSG",
        "title": "Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2",
        "abstract": "From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV) crossed the species barriers to infect humans caused thousands of infections and hundreds of deaths, respectively. Currently, a novel coronavirus (SARS‐CoV‐2) causes the outbreaks of Coronavirus Disease 2019 (COVID‐19) was discovered. Until February 18, 2020, there are 72533 confirmed COVID‐19 cases (including 10644 severe cases) and 1872 deaths in China. SARS‐CoV‐2 is surging in the public and caused substantial burdens due to its human‐to‐human transmission. However, the intermediate host of SARS‐CoV‐2 is still unclear. Finding the possible intermediate host of SARS‐CoV‐2 is imperative to prevent further spread of the epidemic. In this study, we used systematic comparison and analysis to predict the interaction between the receptor binding domain (RBD) of coronavirus spike protein and the host receptor, Angiotensin Converting Enzyme 2 (ACE2). The interaction between the key amino acids of S protein RBD and ACE2 indicated that like previous suggested pangolins and snacks, the turtles (C. picta bellii, C. mydas, and P. sinensis) may act as the potential intermediate hosts transmitting SARS‐CoV‐2 to human.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhixin Liu",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Xiao Xiao",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Xiuli Wei",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Jian Li",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Jing Yang",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Huabing Tan",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Jianyong Zhu",
                "org": "Hubei University of Medicine"
            },
            {
                "name": "Qiwei Zhang",
                "org": "Jinan University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Jinan University"
            },
            {
                "name": "Long Liu",
                "org": "Hubei University of Medicine"
            }
        ],
        "venue": "JMV",
        "year": 2020
    },
    "bVwUO10M": {
        "id": "bVwUO10M",
        "title": "What drives urban growth in China? A multi-scale comparative analysis",
        "abstract": "Abstract   Driving forces of urban growth differ across spatial scales, but most previous studies have been done for single cities of different sizes. Multi-scale analysis of urbanization drivers is still lacking. In this study, we investigated the drivers of urban growth in the central Yangtze River Delta, China from 1990 to 2008, using a hierarchical patch dynamics (HPD) approach that consisted of three spatial scales or hierarchical administrative levels of county, prefecture, and the region. Logistic regression, partial least square regression, and Pearson correlations were used to identify specific drivers. Our results show that the main drivers of urban growth differed between hierarchical levels and over time. First, urban growth occurred frequently next to existing urban land for most cities at all the hierarchical levels, while accessibility to railways, waters and prefectural cities became unimportant to urban expansion over time. Second, GDP, non-agricultural population proportion, gross industrial output and foreign investment in actual use were the top four important socioeconomic factors influencing urban growth for the majority of cities at both the prefectural and county levels, but the relative importance of the key influencing factors of urban growth differed across different hierarchical levels. Third, economic policies and institutional shifts by the central and local governments also played an important role in urban growth especially for cities of Wuxi and Changzhou. These multiscale relations of urban growth to potential drivers, revealed via the HPD approach, are useful for strategic planning to curb excessive urban expansion in the study region. Although the geographical and socioeconomic variables could independently explain more than 75% of variations of urban growth across spatial and temporal scales, the impacts of their interactions on urban growth need further studies in the future.",
        "keywords": "",
        "authors": [
            {
                "name": "Cheng Li",
                "org": ""
            },
            {
                "name": "Junxiang Li",
                "org": "School of Ecological and Environmental Sciences, East China Normal University, Shanghai, 200241, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences & School of Sustainability, Arizona State University, Tempe, AZ, 85287-4501, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences & School of Sustainability, Arizona State University, Tempe, AZ, 85287-4501, USA"
            }
        ],
        "venue": "Applied Geography",
        "year": 2018
    },
    "iYCRokbh": {
        "id": "iYCRokbh",
        "title": "Primary production and rain use efficiency across a precipitation gradient on the Mongolia Plateau.",
        "abstract": "Understanding how the aboveground net primary production (ANPP) of arid and semiarid ecosystems of the world responds to variations in precipitation is crucial for assessing the impacts of climate change on terrestrial ecosystems. Rain-use efficiency (RUE) is an important measure for acquiring this understanding. However, little is known about the response pattern of RUE for the largest contiguous natural grassland region of the world, the Eurasian Steppe. Here we investigated the spatial and temporal patterns of ANPP and RUE and their key driving factors based on a long-term data set from 21 natural arid and semiarid ecosystem sites across the Inner Mongolia steppe region in northern China. Our results showed that, with increasing mean annual precipitation (MAP), (1) ANPP increased while the interannual variability of ANPP declined, (2) plant species richness increased and the relative abundance of key functional groups shifted predictably, and (3) RUE increased in space across different ecosystems but decreased with increasing annual precipitation within a given ecosystem. These results clearly indicate that the patterns of both ANPP and RUE are scale dependent, and the seemingly conflicting patterns of RUE in space vs. time suggest distinctive underlying mechanisms, involving interactions among precipitation, soil N, and biotic factors. Also, while our results supported the existence of a common maximum RUE, they also indicated that its value could be substantially increased by altering resource availability, such as adding nitrogen. Our findings have important implications for understanding and predicting ecological impacts of global climate change and for management practices in arid and semiarid ecosystems in the Inner Mongolia steppe region and beyond.",
        "keywords": [
            "nitrogen addition",
            "eurasian steppe",
            "rain-use efficiency.",
            "plant functional group composition",
            "anpp",
            "ecosystem management",
            "mean annual precipitation",
            "arid and semiarid land",
            "inner mongolia grassland",
            "global climate change",
            "climate change",
            "nitrogen",
            "primary production",
            "relative abundance",
            "terrestrial ecosystems"
        ],
        "authors": [
            {
                "name": "Yongfei Bai",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Qi Xing",
                "org": ""
            },
            {
                "name": "Qingmin Pan",
                "org": ""
            },
            {
                "name": "Jianhui Huang",
                "org": ""
            },
            {
                "name": "Dianling Yang",
                "org": ""
            },
            {
                "name": "Xingguo Han",
                "org": "State Key Laboratory of Vegetation and Environmental Change|Institute of Botany|Chinese Academy of Sciences"
            }
        ],
        "venue": "Ecology",
        "year": 2008
    },
    "QCu9I353": {
        "id": "QCu9I353",
        "title": "A Genre Analysis of the Employment Advertisement",
        "abstract": "As a popular sub-genre of advertisement discourse,the employment advertisement plays an important role in people's life and communication.This paper selects 30 employment advertisements from Guangzhou Daily,Nanfang Daily and South Metropolis News and summarizes their global schematic structures.Based upon this,the paper reveals the communicative purposes of employment advertisements as well as the power relationship between employers and employees through the analysis of moves and steps.",
        "keywords": [
            "communicative purpose",
            "employment advertisement",
            "power relationship",
            "genre analysis"
        ],
        "authors": [
            {
                "name": "WANG Jing",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou ,Guangdong,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou ,Guangdong,China"
            }
        ],
        "venue": "Journal of South China University of Technology(Social Science Edition)",
        "year": 2012
    },
    "2rQgPTqy": {
        "id": "2rQgPTqy",
        "title": "Conversions between natural wetlands and farmland in China: A multiscale geospatial analysis.",
        "abstract": "Agricultural activity is widely recognized as a leading driver of natural wetland loss in many parts of the world. However, little is known about the spatiotemporal patterns of conversion between natural wetlands and farmland in China. This information deficiency has limited decision-making for the sustainable management of natural wetland ecosystems. In this study, we explicitly quantified bidirectional natural wetland-farmland conversions during the periods of 1990-2000 and 2000-2010 at multiple spatiotemporal scales. Our results revealed that about 60% (15,765km) of China's lost natural wetlands were due to agricultural encroachment for grain production, 74.7% (11,778km) of which occurred from 1990 to 2000. Natural wetland conversion to farmland was highest in Northeast China (13,467km or 85.4%), whereas the natural wetlands in Northwest China demand extra attention because of a notable increase of agricultural encroachment. Natural wetlands in the humid zone experienced tremendous agricultural encroachment, leading to a loss of 10,649km, accounting for 67.5% of the total agriculture-induced natural wetland loss in China. On the other hand, a total of 1369km of natural wetlands were restored from farmland, with 66.3% of this restoration occurring between 2000 and 2010, primarily in Northeast China and the humid zone. Although a series of national policies and population pressure resulted in agricultural encroachment into natural wetlands, there are also policies and management measures protecting and restoring natural wetlands in China. The spatial differences in natural wetland-farmland conversions among different geographic regions and climatic zones suggest that China must develop place-based sustainable management policies and plans for natural wetlands. This study provides important scientific information necessary for developing such policies and implementation plans.",
        "keywords": [
            "Agricultural encroachment",
            "ChinaCover",
            "Farmland",
            "Natural wetlands",
            "Wetland restoration"
        ],
        "authors": [
            {
                "name": "Dehua Mao",
                "org": "Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, 130102, China; School of Life Sciences, Arizona State University, Tempe, 85287, USA."
            },
            {
                "name": "Ling Luo",
                "org": "Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, 130102, China."
            },
            {
                "name": "Zongming Wang",
                "org": "Key Laboratory of Wetland Ecology and Environment, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, 130102, China. Electronic address: zongmingwang@iga.ac.cn."
            },
            {
                "name": "Maxwell C Wilson",
                "org": "School of Life Sciences, Arizona State University, Tempe, 85287, USA."
            },
            {
                "name": "Yuan Zeng",
                "org": "Institute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, Beijing, 100094, China."
            },
            {
                "name": "Bingfang Wu",
                "org": "Institute of Remote Sensing and Digital Earth, Chinese Academy of Sciences, Beijing, 100094, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, Arizona State University, Tempe, 85287, USA; School of Sustainability and Julie A. Wrigley Global Institute of Sustainability, Arizona State University, Tempe, 85287, USA; Center for Human-Environment System Sustainability (CHESS), Beijing Normal University, Beijing, 100875, China."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "PFt7zv1H": {
        "id": "PFt7zv1H",
        "title": "Ecological consequences of the Three Gorges Dam: insularization affects foraging behavior and dynamics of rodent populations",
        "abstract": "",
        "keywords": [
            "foraging behavior",
            "species richness",
            "habitat destruction",
            "habitats",
            "foraging",
            "biodiversity",
            "stable isotopes",
            "behaviour",
            "ecosystems"
        ],
        "authors": [
            {
                "name": "Jianzhu Wang",
                "org": ""
            },
            {
                "name": "Jianhui Huang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Xingguo Han",
                "org": ""
            },
            {
                "name": "Guanghui Lin",
                "org": ""
            }
        ],
        "venue": "Frontiers in Ecology and The Environment",
        "year": 2010
    },
    "VYBpLo1n": {
        "id": "VYBpLo1n",
        "title": "Strategies of Adaptation to Climate Change for Rare or Endangered Species in China",
        "abstract": "The strategies of adaptation to climate change for rare or endangered species in China were suggested based on the analyzing the impacts of climate change on rare or endangered species,and the option of adaptation to climate change for some rare or endangered species were analyzed.The vulnerability of species under climate change includes: the reduction of distribution,habitat fragmentation,decline of abundance and group size,population extinction,habitat degradation or loss.The strategies of adaptation to climate change for rare or endangered species in China should consider analyzing the natural adaptation mechanism,strengthening situ-conservation,increasing the population size,developing ex situ conservation and genetics protection techniques,reducing other disturbance or threat factors to species,protecting and restoring the habitat of rare or endangered species,and taking of adaptation measures in protection areas,etc..The strategies of adaptation to climate change for species should be considered based on the state of endangered species and the vulnerability of species under climate change.The limited species were analyzed in this study,and every species should be assessed in detail for adaptation to climate change.",
        "keywords": [
            "strategies of adaptation",
            "rare and endangered species",
            "climate change"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "LV Jia-jia",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "ZHOU Qiao-fu",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "China Population,Resources and Environment",
        "year": 2011
    },
    "bQWLGbKV": {
        "id": "bQWLGbKV",
        "title": "Antioxidant activities of extract and fractions from receptaculum nelumbinis and related flavonol glycosides.",
        "abstract": "The antioxidant activities of ethanolic crude extract (ECE) and its four different solvent sub-fractions (namely, petroleum ether fraction (PEF), ethyl acetate fraction (EAF), n-butanol fraction (BF) and the aqueous fraction (AF) from the receptacles of Nelumbo nucifera Gaertn. (Receptaculum Nelumbinis) were investigated using two in vitro antioxidant assays. BF showed the highest total phenolic content (607.6 mg/g gallic acid equivalents), total flavonoid content (862.7 mg/g rutin equivalents) and total proanthocyanidin content (331.0 mg/g catechin equivalents), accompanied with the highest antioxidant activity compared to other fractions through 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radical scavenging assays. Five flavonol glycosides, namely hyperoside (1), isoquercitrin (2), quercetin-3-O-β-d-glucuronide (3), isorhamnetin-3-O-β-d-galactoside (4) and syringetin-3-O-β-d-glucoside (5) were isolated from the Receptaculum Nelumbinis. Compounds 2-5 were isolated for the first time from the Receptaculum Nelumbinis. The five isolated flavone glycosides, particularly compounds 1-3, demonstrated significant DPPH and ABTS radical scavenging activity, with IC(50) values of 8.9 ± 0.2, 5.2 ± 0.2, 7.5 ± 0.1 for DPPH and 114.2 ± 1.7, 112.8 ± 0.8, 172.5 ± 0.7 μg/mL for ABTS, respectively. These results suggest that Receptaculum Nelumbinis has strong antioxidant potential and may be potentially used as a safe and inexpensive bioactive source of natural antioxidants.",
        "keywords": [
            "abts",
            "dpph",
            "nelumbo nucifera gaertn.",
            "receptacle",
            "molecular",
            "sciences",
            "biomedical research",
            "bioinformatics"
        ],
        "authors": [
            {
                "name": "Yan-Bin Wu",
                "org": "Academy of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; E-Mails: wxsq1@163.com (Y.-B.W.); zhenglijun1985@163.com (L.-J.Z.); wjg1419@126.com (J.-G.W.)."
            },
            {
                "name": "Li-Jun Zheng",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Ti-Qiang Chen",
                "org": ""
            },
            {
                "name": "Jun Yi",
                "org": ""
            },
            {
                "name": "Jin-Zhong Wu",
                "org": ""
            }
        ],
        "venue": "International journal of molecular sciences",
        "year": 2012
    },
    "bSl87Wlm": {
        "id": "bSl87Wlm",
        "title": "Remote virtual touch system based on infrared laser pointer",
        "abstract": "To realize virtual touch far away in business,conference and education area one remote virtual touch system based on infrared laser pointer is presented. System is consisted of infrared laser pointer,large scale display systems,image acquisition equipments and image processing module. Images of infrared laser pointer dot and display surface are captured by image acquisition equipments which are made up of infrared camera,ordinary camera,spectroscope and infrared filter or made up of infrared camera,infrared filter and drive setting. Corresponding relation between image coordinates and display coordinates is constructed in image processing module used by image recognition technology. A point in image is converted to a point in screen according to above relation,and then computer is controlled to show cursor,execute click,execute double click and move cursor operation in corresponding coordinate position based on infrared laser point occurrence and persistence. Experimental result shows indicated that infrared laser pointer is significantly better than standard laser pointer which could only indicate something or page down and page up due to its click ability.",
        "keywords": [
            "spectroscope",
            "infrared filter",
            "virtual touch",
            "image recognition",
            "infrared laser"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": " School of Computer Science and Technology,Anhui University,Hefei ,China; Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": " School of Computer Science and Technology,Anhui University,Hefei ,China; Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": " School of Computer Science and Technology,Anhui University,Hefei ,China; Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Design",
        "year": 2010
    },
    "2cgC3jci": {
        "id": "2cgC3jci",
        "title": "Two cis-acting elements in negative RNA strand of Hepatitis C virus involved in synthesis of positive RNA strand in vitro.",
        "abstract": "Sequences at the 3'-ends of both positive and negative strands of Hepatitis C virus (HCV) RNA harbor cis-acting elements required for RNA replication. However, little is known about the properties of the negative RNA strand as a template for the synthesis of positive RNA strand. In this study, a purified recombinant HCV RNA-dependent RNA polymerase (RdRp) was used to investigate the synthesis of positive RNA strand using the 3'-terminal region of negative RNA strand ((-)3'T RNA) as template. A mutagenesis analysis was performed to evaluate the role of the 3'-proximal stem-loop and the first 3'-cytidylate (3'C) of the negative RNA strand in the synthesis of the positive RNA strand. A negative RNA strand of wild type (wt) HCV as template was able to direct the synthesis of a full-length positive RNA strand. Deletion of the 3'-proximal stem-loop resulted in an approximately 90% decrease in RNA synthesis. Disruption of the 3'-proximal stem-loop structure by nucleotide substitutions led to a 70-80% decrease in RNA synthesis. However, the restoration of the stem-loop by compensatory mutations in the stem region restored also the RNA synthesis. Likewise, the deletion or substitution of the first 3'C by guanylate (G) led to a 90% decrease in the RNA synthesis; while the substitution by adenylate (A) or uridylate (U) resulted in a 60-80% decrease in the RNA synthesis only. These findings demonstrate that the 3'-proximal stem-loop and the first 3'C of the negative RNA strand of HCV are two cis-acting elements involved in the synthesis of the positive RNA strand.",
        "keywords": [
            "rna-dependent rna polymerase",
            "rna synthesis",
            "negative rna strand",
            "hepatitis c virus",
            "cis-acting element",
            "rna",
            "positive rna strand"
        ],
        "authors": [
            {
                "name": "L Ye",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "K A Timani",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "L Ye",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "L Kong",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "X Yang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Q Liao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "J Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Acta virologica",
        "year": 2005
    },
    "6g6xFtxf": {
        "id": "6g6xFtxf",
        "title": "Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication",
        "abstract": "Hepatitis B virus (HBV) infection causes acute and chronic liver diseases, but is not directly cytopathic. Liver injury results from repeated attempts of the cellular immune response system to control the viral infection. Here, we investigate the roles of cellular factors and signaling pathways involved in the regulation of HBV replication to reveal the mechanism underlying HBV infection and pathogenesis. We show that collagen triple helix repeat containing 1 (CTHRC1) expression is elevated in HBV-infected patients and in HBV-transfected cells through epigenetic modification and transcriptional regulation. CTHRC1 facilitates HBV replication in cultured cells and BALB/c mice by activating the PKCERK/JNK/c-Jun cascade to repress the IFN/JAK/STAT pathway. HBV-activated CTHRC1 downregulates the activity of type I interferon (IFN), the production of IFN-stimulated genes (ISGs), and the phosphorylation of signal transducer and activator of transcription 1/2 (STAT1/2), whereas it upregulates the phosphorylation and ubiquitination of type I IFN receptors (IFNAR). Thus, our results show that HBV uses a novel mechanism to hijack cellular factors and signal cascades in order to evade host antiviral immunity and maintain persistent infection. We also demonstrate that CTHRC1 has a novel role in viral infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Lan Bai",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Li Tan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Hongchuan Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Maolin Ge",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Chengliang Zhu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Rui Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Yanhua Cao",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Zhen Luo",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Wenzhe Ho",
                "org": ""
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            }
        ],
        "venue": "Journal of Molecular Cell Biology",
        "year": 2015
    },
    "p73Z0ok5": {
        "id": "p73Z0ok5",
        "title": "Selection of Glutathione-overprouducing Mutants by Complex Mutation",
        "abstract": "Objective:To screen a mutant with high glutathione yield.Method:A producing glutathione candida utilis was treated with UV and Ultrasonic.Result:Followed by resistance selection with zinc chloride,a high yield named UU3 was obtained,and the glutathione content of the mutant reached 53.50mg·g-1 in the dried cells,which was increased 137.3% more than the starting strain.Conclusion:The genetic stability of the mutant UU3 was good,and it can be further studied.",
        "keywords": [
            "Candida utilis",
            "complex mutation",
            "ultrasonic",
            "glutathione",
            "UV"
        ],
        "authors": [
            {
                "name": "GAN Guang-dong",
                "org": "Sichuan University of Science & Engineering Bioengineering Department,Zigong 64300,China"
            },
            {
                "name": "LIU Qing-bin",
                "org": "Sichuan University of Science & Engineering Bioengineering Department,Zigong 64300,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Sichuan University of Science & Engineering Bioengineering Department,Zigong 64300,China"
            },
            {
                "name": "ZHANG Xue-feng",
                "org": "Sichuan University of Science & Engineering Bioengineering Department,Zigong 64300,China"
            }
        ],
        "venue": "Biotechnology",
        "year": 2008
    },
    "Ca53uqkH": {
        "id": "Ca53uqkH",
        "title": "Sound absorption property of open-pore aluminum foams",
        "abstract": "The sound absorption property of aluminum foam was studied by testing its sound absorption coefficients using standing wave tube method. The open-pore aluminum foams were prepared by infiltration process, with pore size of 0.5 mm to 3.2 mm and porosity of 54.2% to 77%. The frequency of indicted sound wave was ranging from 125 Hz to 10 kHz. The results show that the average values of sound absorption coefficients are all over 0.4 and the aluminum foam has better sound absorption property, its coefficients is influenced by frequency and pore structure, and reaches the maximum at about 1 kHz, with increasing porosity and decreasing cell diameter the sound absorption coefficient values increase.",
        "keywords": [
            "pore structure",
            "sound absorption coefficient",
            "sound absorption coefficients",
            "aluminum foam",
            "plane-wave impedance tube",
            "sound absorption property"
        ],
        "authors": [
            {
                "name": "WANG Lu-cai",
                "org": ""
            },
            {
                "name": "WANG Fang",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "YOU Xiao-hong",
                "org": ""
            }
        ],
        "venue": "中国有色金属学会会刊(英文版)",
        "year": 2006
    },
    "5uostnbc": {
        "id": "5uostnbc",
        "title": "Characterization and fine mapping of the glabrous leaf and hull mutants (gl1) in rice (Oryza sativa L.).",
        "abstract": "The glabrous leaf and hull (gl1) mutants were isolated from M2 generation of indica cultivar 93-11. These mutants produced smooth leaves and hairless glumes under normal growth conditions. By analyzing through\n scanning electron microscope, it was revealed that the leaf trichomes, including macro and micro hairs, were deficient in\n these mutants. Genetic analysis indicated that the mutation was controlled by a single recessive gene. Using nine SSR markers\n and one InDel marker, the gl1 gene was mapped between RM1200 and RM2010 at the short arm of chromosome 5, which was consistent with the mapping of gl1 in previous studies. To facilitate the map-based cloning of the gl1 gene, 12 new InDel markers were developed. A high-resolution genetic and physical map was constructed by using 1,396 mutant\n individuals of F2 mapping population. Finally, the gl1 was fine mapped in 54-kb region containing 10 annotated genes. Cloning and sequencing of the target region from four gl1 mutants (gl1-1, gl1-2, gl1-3 and gl1-4) and four glabrous rice varieties (Jackson, Jefferson, Katy and Lemont) all showed\n that the same single point mutation (A→T) occurred in the 5′-untranslated region (UTR) of the locus Os05g0118900 (corresponding to the 3′-UTR of STAR2). RT-PCR analysis of the locus Os05g0118900 revealed that its mRNA expression level was normal in gl1 mutant. RNA secondary structure prediction showed that the single point mutation resulted in a striking RNA conformational\n change. These results suggest that the single point mutation is most likely responsible for the glabrous leaf and hull phenotypes\n in rice.",
        "keywords": [
            "glabrous leaf and hull",
            "trichome",
            "rice",
            "map-based cloning",
            "gl1",
            "point mutation",
            "high resolution",
            "gene cloning",
            "genetic analysis",
            "untranslated region",
            "scanning electron microscope",
            "genetics"
        ],
        "authors": [
            {
                "name": "Wenqiang Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Shili Weng",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Dapeng Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yujiang Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Plant cell reports",
        "year": 2010
    },
    "LBgxS5rl": {
        "id": "LBgxS5rl",
        "title": "Towards a better understanding of landscape patterns and ecosystem processes of the Mongolian Plateau",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jingyun fang",
                "org": "peking university"
            },
            {
                "name": "yongfei bai",
                "org": "chinese academy of sciences"
            },
            {
                "name": "jianguo wu",
                "org": "beijing normal university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "osiqLlmj": {
        "id": "osiqLlmj",
        "title": "The relationship between urban form and air pollution depends on seasonality and city size.",
        "abstract": "Understanding how urban form is related to air pollution is important to urban planning and sustainability, but the urban form-air pollution relationship is currently muddled by inconsistent findings. In this study, we investigated how the compositional and configurational attributes of urban form were related to different air pollution measures (PM, API, and exceedance) in 83 Chinese cities, with explicit consideration of city size and seasonality. Ten landscape metrics were selected to quantify urban form attributes, and Spearman's correlation was used to quantify the urban form-air pollution relationship. Our results show that the urban form and air pollution relationship was dominated by city size and moderated by seasonality. Specifically, urban air pollution levels increased consistently and substantially from small to medium, large, and megacities. The urban form-air pollution relationship depended greatly on seasonality and monsoons. That is, the relationship was more pronounced in spring and summer than fall and winter, as well as in cities affected by monsoons. Urban air pollution was correlated more strongly with landscape composition metrics than landscape configuration metrics which seemed to affect only PM concentrations. Our study suggests that, to understand how air pollution levels are related to urban form, city size and seasonality must be explicitly considered (or controlled). Also, in order to mitigate urban air pollution problems, regional urban planning is needed to curb the spatial extent of built-up areas, reduce the degree of urban fragmentation, and increase urban compactness and contiguity, especially for large and megacities.",
        "keywords": [
            "Air Pollution Index",
            "Built-up area",
            "Exceedance",
            "PM2.5",
            "Urban morphology",
            "Urban sprawl"
        ],
        "authors": [
            {
                "name": "Yupeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, No. 19, XinJieKouWai Street, Haidian District, Beijing, 100875, People's Republic of China."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ, 85287, USA. Jingle.Wu@asu.edu."
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, No. 19, XinJieKouWai Street, Haidian District, Beijing, 100875, People's Republic of China. ydy@bnu.edu.cn."
            },
            {
                "name": "Qun Ma",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, No. 19, XinJieKouWai Street, Haidian District, Beijing, 100875, People's Republic of China."
            }
        ],
        "venue": "Environmental science and pollution research international",
        "year": 2018
    },
    "koySSU9k": {
        "id": "koySSU9k",
        "title": "\"GuZhangJueChen\"and Multi-Chapter Imitative Works of Huaben",
        "abstract": "Contraposing the inborn shortage of single-chapter imitative works of Huaben in complex narrating,JinMuSanRen's GuZhangJueChen uses the voluminous chapter novel's multi-chapter narrating form to rebuild it.So GuZhangJueChen breaks the imitative works of Huaben novel's tranditional narrating model,cuts a new persisting development of inditing way and tries to make a symmetric,tidy and formal multi-chapter imitative works of Huaben narrating pattern.But it makes the works existing an obvious aesthetic trend because of sedulously pursing the trimness.",
        "keywords": [
            "Multi-chapter Imitative Works of Huaben novel",
            "GuZhangJueChen",
            "Complex Narrating"
        ],
        "authors": [
            {
                "name": "Zhao Xu",
                "org": "Liberal Arts College of Hunan Normal University,Hunan Changsha,"
            },
            {
                "name": "Wu Jian-guo",
                "org": "Liberal Arts College of Hunan Normal University,Hunan Changsha,"
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2005
    },
    "2I1UGyoT": {
        "id": "2I1UGyoT",
        "title": "Developmental Genetic Analysis for Protein Content of Rapeseed Meal in Different Developmental Environments",
        "abstract": "The genetic main effects and genotype × environment(GE) interaction effects of embryo,cytoplasm and maternal genetic systems on the protein content(PC) of rapeseed meal were analyzed from two-year experimental data under different growing conditions by using both conditional and unconditional analysis methods.Results: Embryo nuclear genes,cytoplasmic genes and maternal plant nuclear genes simultaneously control PC of rapeseed meal,among which diploid maternal plant effect and additive effect are of critical importance.The GE interaction effects also show significant influence on the gene expression patterns for PC during all the seed development stages,especially for the maternal interaction effects.The differences and discontinuity of gene expression during seed development are also observed by using the conditional analysis method.The heritability analysis reveals that the maternal heritability is more prominent for PC during seed development times,except the 22nd day post anthesis.Thus it is suggested that maternal plant selection can be utilized to improve PC in rapeseed breeding program.The study further suggests that Zhongyou 821 and Eyouchangjia are better than other parents for increasing PC of rapeseed meal in progenies.",
        "keywords": [
            "genetic main effects",
            "genotype environment interaction effects",
            "developmental genetics",
            "protein content",
            "rapeseed(Brassica napus L.)"
        ],
        "authors": [
            {
                "name": "Zhang Li",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou "
            },
            {
                "name": "Wu Jianguo",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou "
            },
            {
                "name": "Chen Guolin",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou "
            },
            {
                "name": "Shi Chunhai",
                "org": "Department of Agronomy,Zhejiang University,Hangzhou "
            }
        ],
        "venue": "Journal of the Chinese Cereals and Oils Association",
        "year": 2010
    },
    "UHa2wmNt": {
        "id": "UHa2wmNt",
        "title": "Dynamic analyze of ship launching with air-bag",
        "abstract": "This article presents the hydrodynamic analyze method of ship launching with air-bag.The hydrodynamic equation was established and solved by fourth order Runge-Kutta method.The comparison between calculation and measured results of multiple ship launching with air-bag shows that the hydrodynamic analyze method and the equation described are reasonable.",
        "keywords": [
            "ship launching with air-bag",
            "Runge-Kutta method",
            "hydrodynamic"
        ],
        "authors": [
            {
                "name": "LI Yu-fen",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "FENG Hua",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Ship & Boat",
        "year": 2011
    },
    "71QhRdtT": {
        "id": "71QhRdtT",
        "title": "Erratum to: Habitat fragmentation and biodiversity conservation: key findings and future challenges",
        "abstract": "Landscape Ecol DOI 10.1007/s10980-015-0312-3 EDITORIAL Habitat fragmentation and biodiversity conservation: key findings and future challenges Maxwell C. Wilson . Xiao-Yong Chen . Richard T. Corlett . Raphael K. Didham . Ping Ding . Robert D. Holt . Marcel Holyoak . Guang Hu . Alice C. Hughes . Lin Jiang . William F. Laurance . Jiajia Liu . Stuart L. Pimm . Scott K. Robinson . Sabrina E. Russo . Xingfeng Si . David S. Wilcove . Jianguo Wu . Mingjian Yu Received: 5 November 2015 / Accepted: 7 November 2015 Springer Science+Business Media Dordrecht 2015 Habitat loss and fragmentation has long been consid- ered the primary cause for biodiversity loss and ecosystem degradation worldwide, and is a key research topic in landscape ecology (Wu 2013). Habitat fragmentation often refers to the reduction of continuous tracts of habitat to smaller, spatially distinct remnant patches, and habitat loss typically occurs concurrently with habitat fragmentation (Col- linge 2009). Although some habitats are naturally patchy in terms of abiotic and biotic conditions (Wu and Loucks 1995), human actions have profoundly fragmented landscapes across the word (Haddad et al. 2015), altering the quality and connectivity of habitats. Therefore, understanding the causes and conse- quences of habitat fragmentation is critical to preserv- ing biodiversity and ecosystem functioning. From May 4th to 10th, 2015, an International Workshop on Habitat Fragmentation and Biodiversity Conservation, held at the Thousand Island Lake, Zhejiang, China, discussed threats to biodiversity in fragmented landscapes and how fragmentation research can identify and help mitigate these threats. M. C. Wilson J. Wu School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA e-mail: mcwilso2@gmail.com P. Ding (u0026) J. Liu X. Si M. Yu (u0026) College of Life Sciences u0026 Institute of Ecology, Zhejiang University, Hangzhou 310058, Zhejiang, China e-mail: dingping@zju.edu.cn X.-Y. Chen School of Ecological and Environmental Sciences, East China Normal University, Shanghai 200214, China R. T. Corlett A. C. Hughes Centre for Integrative Conservation, Xishuangbanna Tropical Botanic Garden, Chinese Academy of Sciences, Menglun, Mengla 666303, Yunnan, China R. K. Didham School of Animal Biology, University of Western Australia, Perth, WA 6009, Australia R. K. Didham CSIRO Land and Water, Centre for Environment and Life Sciences, Perth, WA 6014, Australia M. Yu e-mail: fishmj202@hotmail.com R. D. Holt Department of Biology, University of Florida, Gainesville, FL 32611, USA M. Holyoak Department of Environmental Science and Policy, University of California, Davis, CA 95616, USA G. Hu Department of Landscape Architecture, School of Civil Engineering and Architecture, Zhejiang University of Science and Technology, Hangzhou 310018, Zhejiang, China",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell C. Wilson",
                "org": "Arizona State University"
            },
            {
                "name": "Xiao-Yong Chen",
                "org": "East China Normal University"
            },
            {
                "name": "Richard T. Corlett",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Raphael K. Didham",
                "org": "University of Western Australia"
            },
            {
                "name": "Ping Ding",
                "org": "Zhejiang University"
            },
            {
                "name": "Robert D. Holt",
                "org": "University of Florida"
            },
            {
                "name": "Marcel Holyoak",
                "org": "University of California"
            },
            {
                "name": "Guang Hu",
                "org": "Zhejiang Sci-Tech University"
            },
            {
                "name": "Alice C. Hughes",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Lin Jiang",
                "org": "School of Biology,Georgia Institute of Technology,Atlanta,USA"
            },
            {
                "name": "William F. Laurance",
                "org": "James Cook University"
            },
            {
                "name": "Jiajia Liu",
                "org": "Zhejiang University"
            },
            {
                "name": "Stuart L. Pimm",
                "org": "Duke University"
            },
            {
                "name": "Scott K. Robinson",
                "org": "University of Florida"
            },
            {
                "name": "Sabrina E. Russo",
                "org": "University of Nebraska-Lincoln"
            },
            {
                "name": "Xingfeng Si",
                "org": "Zhejiang University"
            },
            {
                "name": "David S. Wilcove",
                "org": "Princeton University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University"
            },
            {
                "name": "Mingjian Yu",
                "org": "College of Life Sciences & Institute of Ecology,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2016
    },
    "RpcN8g2A": {
        "id": "RpcN8g2A",
        "title": "The potential effects of climate change on the distributions of 7 plants in China",
        "abstract": "The effects of climate change on the distributions of Falsepistache(Tapiscia sinensis),Black Crowberry(Empetrum nigrum),Wakerobin(Trillium tschonoskii),Field Circaeaster(Circaesaster agrestis),Gastrodia(Gastrodia elata),Beauty Bush(Kolkwitzia amabilis)and Flous Taiwania(Taiwania flousiana)in China were analyzed using the CART(classification and regression tree)model and climate change scenarios of A2 and B2. The results showed that climate change in China would cause an increase in the current distribution of Falsepistache,and it would cause a decrease in current distribution of other plants. The new distribution or total distribution region of Beauty Bush,Wakerobin or Falsepistache would increase,while Field Circaeaster or Black Crowberry would decrease,and that of Gastrodia or Flous Taiwania would increase from periods of 1991-2020 to periods of 2051-2080,then they would decrease,and they were higher in A2 scenario than that in B2 Scenario. New suitable regions of these plants would expand towards high altitude regions or latitude regions. And the distribution regions of Gastrodia would mainly expand towards high altitude regions,while Flous Taiwania,Beauty Bush,Field Circaeaster or Gastrodia would expand towards high altitude regions or latitude regions,and Falsepistache would expand towards high altitude regions or northeast latitude regions,while Black Crowberry would expand towards high altitude regions or latitude regions,and the distribution regions of that would lost from periods of 2051-2080 to periods of 2081-2100. Additionally,under climate change,changing in current distribution,new distribution or total distribution region of the plants did not consistently change with changing in annual mean air temperature or precipitation in China,and the changing in current distribution,new distribution or total distribution region of some plants were poor related with changing in annual mean air temperature or precipitation in China. And the linear regression relationship between changing in the plants distribution and annual mean temperature and annual mean precipitation in China were different for different plants,while the linear regression relationship between changing in the plants distribution and annual mean temperature and annual mean precipitation in China were poor. The results indicated that climate change in China would cause decrease in the current distribution region of the animals except Falsepistache,and it would cause expand the distribution of the plants towards high altitude or high latitude regions. And the relationship between changing in the plants distribution and annual mean temperature and annual mean precipitation in China were different.",
        "keywords": [
            "endangered plant",
            "spatial distribution pattern",
            "CART model",
            "climate change"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": " Chinese Research Academy of Environmental Sciences, Beijing , China "
            }
        ],
        "venue": "Guihaia",
        "year": 2011
    },
    "4BRUT00U": {
        "id": "4BRUT00U",
        "title": "Linking wind erosion to ecosystem services in drylands: a landscape ecological approach",
        "abstract": "Wind erosion is a widespread environmental problem in the world’s arid landscapes, which threatens the sustainability of ecosystem services in these regions.",
        "keywords": [
            "Wind erosion",
            " Ecosystem services",
            " Drylands",
            " Constraint effect",
            " Mu Us Sandy Land",
            " Inner Mongolia"
        ],
        "authors": [
            {
                "name": "Yuan-Yuan Zhao",
                "org": "Beijing Forestry University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Chunyang He",
                "org": "Beijing Normal University"
            },
            {
                "name": "Guodong Ding",
                "org": "Beijing Forestry University"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2017
    },
    "e2TlYXMx": {
        "id": "e2TlYXMx",
        "title": "Program Automation Based on Arithmetic",
        "abstract": "In recent years,program automation of arithmetic has been becoming one of focused topics in the domain of computer science.Because of the complexity and abstract of arithmetic,many learners often feel that it difficult to understand and master it during learning the arithmetic in practice.In order to learn the arithmetic better,we are seeking for the program automation of arithmetic. This paper discussed the conception and method of the transformation from similar C arithmetic to C++ source program,and gives a compiler that can transform similar C arithmetic to C++ source program automatically.",
        "keywords": [
            "process automation",
            "C++ source",
            "compiler",
            "C algorithm"
        ],
        "authors": [
            {
                "name": "WAN Feng-song",
                "org": "Key laboratory of computational intelligence and signal processing in Anhui University,Hefei ,China"
            },
            {
                "name": "YANG De-sheng",
                "org": "Key laboratory of computational intelligence and signal processing in Anhui University,Hefei ,China"
            },
            {
                "name": "GUO Xing",
                "org": "Key laboratory of computational intelligence and signal processing in Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key laboratory of computational intelligence and signal processing in Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computing Technology and Automation",
        "year": 2008
    },
    "BbCZRD9v": {
        "id": "BbCZRD9v",
        "title": "Co-circulation and genomic recombination of coxsackievirus A16 and enterovirus 71 during a large outbreak of hand, foot, and mouth disease in Central China.",
        "abstract": "A total of 1844 patients with hand, foot, and mouth disease (HFMD), most of them were children of age 1-3-year-old, in Central China were hospitalized from 2011 to 2012. Among them, 422 were infected with coxsackievirus A16 (CVA16), 334 were infected with enterovirus 71 (EV71), 38 were co-infected with EV71 and CVA16, and 35 were infected with other enteroviruses. Molecular epidemiology analysis revealed that EV71 and CVA16 were detected year-round, but EV71 circulated mainly in July and CVA16 circulated predominantly in November, and incidence of HFMD was reduced in January and February and increased in March. Clinical data showed that hyperglycemia and neurologic complications were significantly higher in EV71-infected patients, while upper respiratory tract infection and C-reactive protein were significantly higher in CVA16-associated patients. 124 EV71 and 80 CVA16 strains were isolated, among them 56 and 68 EV71 strains were C4a and C4b, while 25 and 55 CVA16 strains were B1a and B1b, respectively. Similarity plots and bootscan analyses based on entire genomic sequences revealed that the three C4a sub-genotype EV71 strains were recombinant with C4b sub-genotype EV71 in 2B-2C region, and the three CVA16 strains were recombinant with EV71 in 2A-2B region. Thus, CVA16 and EV71 were the major causative agents in a large HFMD outbreak in Central China. HFMD incidence was high for children among household contact and was detected year-round, but outbreak was seasonal dependent. CVA16 B1b and EV71 C4b reemerged and caused a large epidemic in China after a quiet period of many years. Moreover, EV71 and CVA16 were co-circulated during the outbreak, which may have contributed to the genomic recombination between the pathogens. It should gain more attention as there may be an upward trend in co-circulation of the two pathogens globally and the new role recombination plays in the emergence of new enterovirus variants.",
        "keywords": [
            "china",
            "age distribution",
            "phylogeny",
            "incidence",
            "geography"
        ],
        "authors": [
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Shimin Wu",
                "org": "Department of Clinical Laboratory, Wuhan Medical Treatment Center, Wuhan, People's Republic of China."
            },
            {
                "name": "Ying Xiong",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Tongya Li",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Zhou Wen",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Mingzhe Yan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Kai Qin",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, People's Republic of China."
            }
        ],
        "venue": "PloS one",
        "year": 2014
    },
    "wSAKAWrx": {
        "id": "wSAKAWrx",
        "title": "The potential therapeutic targets to bone pain induced by cancer metastasis.",
        "abstract": "About 75-90% of patients with advanced metastatic cancer experience significant cancer pain. Bone cancer pain is one of the most common pains experienced by patients with advanced breast, prostate, or lung cancer. It is characterized by significant skeletal remodeling, fractures, pain, and anemia, all of which reduce the functional status, quality of life, and survival of the patient. Recent years have seen great progress toward alleviating bone pain with the identification of a range of chemicals as well as receptors modulating cancer pain progression. However, the complicated interactions among these factors and, sometimes, the contradicting effects of the same factor in different pathways make it difficult to spot individual effective targets. The sheer quantity of the chemicals involved and the limited understanding from animal models are the constraints in the development of effective therapies for cancer bone pain. In this review, key targets will be discussed along the pain transduction pathway, including peripheral pain sensation, spinal cord transduction pathway, and the central nervous system, to offer a logical and systematic study for the development of combined anti-bone pain treatments.",
        "keywords": [
            "nervous system"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Yibing Wei",
                "org": ""
            },
            {
                "name": "Jingsheng Shi",
                "org": ""
            },
            {
                "name": "Feiyan Chen",
                "org": ""
            },
            {
                "name": "Guangyong Huang",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            },
            {
                "name": "Jun Xia",
                "org": "Department of Orthopedics, Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            }
        ],
        "venue": "Journal of cancer research and therapeutics",
        "year": 2013
    },
    "LrJ7e480": {
        "id": "LrJ7e480",
        "title": "Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter.",
        "abstract": "The hepatitis B virus (HBV) is a major etiological factor of inflammation and damage to the liver resulting in hepatocellular carcinoma. Transcription factors play important roles in the disordered gene expression and liver injury caused by HBV. However, the molecular mechanisms behind this observation have not been defined.In this study, we observed that circulating prostaglandin (PGE) 2 synthesis was increased in patients with chronic hepatitis B infection, and detected elevated cyclooxygenase (COX)-2 expression in HBV- and HBx-expressing liver cells. Likewise, the association of HBx with C/EBPβ contributed to the induction of COX-2. The COX-2 promoter was hypomethylated in HBV-positive cells, and specific demethylation of CpG dinucleotides within each of the two NF-AT sites in the COX-2 promoter resulted in the increased binding affinity of NF-AT to the cognate sites in the promoter, followed by increased COX-2 expression and PGE2 accumulation. The DNA methylatransferase DNMT3B played a key role in the methylation of the COX-2 promoter, and its decreased binding to the promoter was responsible for the regional demethylation of CpG sites, and for the increased binding of transcription factors in HBV-positive cells.Our results indicate that upregulation of COX-2 by HBV and HBx is mediated by both demethylation events and recruitment of multiple transcription factors binding to the promoter.",
        "keywords": [
            "virology",
            "transcription factor",
            "binding affinity",
            "molecular mechanics",
            "gene expression"
        ],
        "authors": [
            {
                "name": "Xin Yue",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Fang Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Yongbo Yang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Wei Sun",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Wei Li",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Dongping Xu",
                "org": "Research Group for Viral Hepatitis, Institute of Infectious Diseases, Beijing 302 Hospital, 100039 Beijing, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute of Wuhan University (Zhongnan Hospital), Wuhan University, 430072 Wuhan, PR China"
            }
        ],
        "venue": "Virology journal",
        "year": 2011
    },
    "xbkaXRD3": {
        "id": "xbkaXRD3",
        "title": "Interaction Between Rice Stripe Virus NS3 Protein and Glyceraldehyde-3-Phosphate Dehydrogenase(GAPDH) of Rice",
        "abstract": "NS3 protein of rice stripe virus (RSV) is an RNA silencing suppressor. Yeast two-hybrid assay was used to screen the rice cDNA library with the NS3 protein as a bait. A novel rice protein interacting with RSV NS3 was obtained. The putative function of the interacting protein was glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Bimolecular fluorescence complementation (BiFC) also showed that RSV NS3 could interact with the GAPDH. Cellular localization studies showed that GAPDH-GFP fusion protein accumulated predominantly in cytoplasm of tobacco (Nicotiana benthamiana) through transient expression assay. Possible functions of GAPDH during the infection of rice by RSV were discussed.",
        "keywords": [
            "yeast two hybrid",
            "protein function",
            "rice stripe virus",
            "bimolecular fluorescence complementation",
            "interaction"
        ],
        "authors": [
            {
                "name": "XIAO Dong-lai",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "JIA Dong-sheng",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "DU Zhen-guo",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "XIE Li-yan",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "WU Zu-jian",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            },
            {
                "name": "XIE Lian-hui",
                "org": "Key Laboratory of Plant Virology of Fujian Province/Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Rice Science",
        "year": 2010
    },
    "Tkfgf457": {
        "id": "Tkfgf457",
        "title": "The urban matrix matters: Quantifying the effects of surrounding urban vegetation on natural habitat remnants in Santiago de Chile",
        "abstract": "Abstract   Urbanization destroys and fragments natural habitats, resulting in a system of natural remnants embedded in an urban matrix. Urban natural remnants (UNRs) can provide multiple ecosystem services for urban areas. Nevertheless, the long-term provision of ecosystem services by UNRs depends on their capacity to retain the ecosystem processes supporting the services. As vegetation from the urban matrix could play a key role in remnants ecological dynamics, understanding the effect of surrounding urban vegetation on UNRs ecosystem processes is fundamental for sustainable urban planning. In this work, we used a multi-temporal and -spatial scale approach to evaluate the role that vegetation patterns (i.e. composition and configuration) of the urban matrix have played on ecosystem processes (i.e. primary productivity) of 10 UNRs located in the city of Santiago (Chile). Using a set of six remote sensing-derived vegetation indices (years 1985–2010), we analyzed how temporal changes in primary productivity of UNRs were related to changes in vegetation patterns of the surrounding urban matrix, and assessed the potential role of the matrix’s socioeconomic level on these results. Our results show that productivity decreased in all UNRs and that this productivity loss was spatially correlated with the changes in vegetation cover of the surrounding urban matrix. UNR productivity was more strongly correlated with matrix composition than matrix configuration. Correlation strength between matrix composition and UNR productivity increased in time and decreased with distance from the edge of UNRs inward, suggesting that the effects of matrix vegetation on the ecological processes within UNRs are both time- and location-dependent. The socioeconomic level of the matrix showed a positive association with the vegetation cover of the matrix, but did not have a statistically significant correlation with UNR primary productivity. Results from our work demonstrate that the changes in urban matrix vegetation induced by urbanization may have strong impacts on the ecological processes that underpin the provision of ecosystem services by UNRs. If planners ought to increase the provision of ecosystem services by these UNRs, the strategies should not only focus on managing vegetation within UNRs, but also on properly planning vegetation in the surrounding urban matrix.",
        "keywords": "",
        "authors": [
            {
                "name": "Ignacio C. Fernández",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            },
            {
                "name": "Javier A. Simonetti",
                "org": "Department of Ecology, University of Chile, Santiago 7800003, Chile"
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2018
    },
    "GF4rmko3": {
        "id": "GF4rmko3",
        "title": "Strategies of Adaptation to Climate Change for Biodiversity in China",
        "abstract": "The vulnerability of biodiversity and its adaptation to climate change are the crucial issues for biodiversity conservation.The strategies of adaptation to climate change for the biodiversity in China were suggested based on the review of the impacts of climate change on biodiversity in China.Climate change in China has caused changes in phonological phase,distribution of species,structure of community,quality of habitity,ecosystem and landscape diversity,etc.,and in future,climate change in China would cause severe impacts on biodiversity.The adaptation to climate change for biodiversity in China should consider the monitoring and assessment of climate change impacts,effectively species protection,planning and management of the protected area,disaster prevention,etc..",
        "keywords": [
            "biodiversity",
            "climate change",
            "the strategies of adaptation"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "Zhou Qiao-fu",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "LI Yan",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "China Population,Resources and Environment",
        "year": 2011
    },
    "5GQZLXAf": {
        "id": "5GQZLXAf",
        "title": "Computer Navigation and Total Knee Arthroplasty",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "gangyong huang",
                "org": ""
            },
            {
                "name": "jun xia",
                "org": ""
            },
            {
                "name": "licheng wei",
                "org": ""
            },
            {
                "name": "jie chen",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "feiyan chen",
                "org": ""
            },
            {
                "name": "siqun wang",
                "org": ""
            },
            {
                "name": "yibing wei",
                "org": ""
            },
            {
                "name": "jingsheng shi",
                "org": ""
            }
        ],
        "venue": "Orthopedics",
        "year": 2014
    },
    "Nam3vRqB": {
        "id": "Nam3vRqB",
        "title": "Investigation of the extracts from Bidens pilosa Linn. var. radiata Sch. Bip. for antioxidant activities and cytotoxicity against human tumor cells.",
        "abstract": "The aim of this study was to evaluate antioxidant activities and cytotoxicity against human tumor cell lines of extracts from Bidens pilosa Linn. var. radiata Sch. Bip. (BP). Total phenolic and flavonoid contents of the extracts were determined by ultraviolet spectrophotometry. Furthermore, the antioxidant properties of different polarity fractions extracted from BP were evaluated using DPPH and ABTS radical scavenging test and FRAP assay. The ethyl acetate fraction (EE-BP) showed the highest antioxidant activity compared to other fractions. In addition, the anti-proliferative activities of the extracts on four human tumor cells, namely MCF-7, HepG2, MGC 803 and RKO, were investigated by MTT method. The EE-BP displayed the most remarkable anti-proliferative effect against the tumor cells, particularly RKO cell in dose- and time-dependent manner. The antioxidant activities and cytotoxicity correlated highly with the total phenolic and flavonoid contents, respectively. Furthermore, The active ingredient BP-6, namely 5,7,4'-trihydroxy-3,3'-dimethyl-flavonol, was isolated and purified with the purity above 99.00% and content of 0.15% in EE-BP detected by HPLC, which could significantly inhibit the proliferation of RKO cells with the IC(50) value of 6.66 μmol/l. In order to characterize the apoptotic RKO cells, flow cytometry and DNA fragmentation assay were performed. Apoptotic cell numbers increased in a dose-dependent manner after the treatment with different concentrations of EE-BP and BP-6 for 12 and 6 h, respectively. DNA ladders in apoptotic RKO cells could be easily visualized when exposed to 200 μg/ml of the EE-BP for 36 h. Taken together, our work indicated that BP had potentially therapeutic value against colorectal cancer.",
        "keywords": [
            "bidens pilosa linn. var. radiata sch. bip.",
            "flavonoids",
            "cytotoxicity",
            "phenolic",
            "colorectal cancer",
            "antioxidant activity"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Fujian University of Traditional Chinese Medicine(Fujian College of Traditional Chinese Medicine,Fujian College of TCM),Fuzhou,China"
            },
            {
                "name": "Zhongxian Wan",
                "org": "Fujian University of Traditional Chinese Medicine(Fujian College of Traditional Chinese Medicine,Fujian College of TCM),Fuzhou,China"
            },
            {
                "name": "Jun Yi",
                "org": "Fujian Institute of Education(Fujian Institute of Education,Fujian Institute of Ophthalmology),Fuzhou,China"
            },
            {
                "name": "Yanbin Wu",
                "org": "Fujian University of Traditional Chinese Medicine(Fujian College of Traditional Chinese Medicine,Fujian College of TCM),Fuzhou,China"
            },
            {
                "name": "Wei Peng",
                "org": "Third Military Medical University(Third Military Medical University),Chongqing,China"
            },
            {
                "name": "Jinzhong Wu",
                "org": "Fujian University of Traditional Chinese Medicine(Fujian College of Traditional Chinese Medicine,Fujian College of TCM),Fuzhou,China"
            }
        ],
        "venue": "Journal of natural medicines",
        "year": 2013
    },
    "yjMBqWNt": {
        "id": "yjMBqWNt",
        "title": "Detection of human endogenous retrovirus env gene in the blood of individuals with schizophrenia by using nested RT-PCR",
        "abstract": "The association between transcriptional activation of HERV and the develop- ment of schizophrenia was investigated. Nested RT-PCR was used to detect the preval- ence of HERV env RNA in the PBMCs of individuals with recent-onset of schizophrenia and normal persons from central and southern China. β-actin gene was used as an internal control. HERV env homologous sequences were found in the PBMCs of 8 of 28 (28.6%) individuals with recent-onset schizophrenia, while no env sequences were identified in any of the PBMCs obtained from 24 normal person (P<0.001). The results suggested that transcriptional activation of HERV might be associated with the develop- pment of schizophr- enia in at least some patients.",
        "keywords": [
            "Human endogenous retroviruses (HERV)",
            "Nested RT-PCR",
            "Schizophrenia"
        ],
        "authors": [
            {
                "name": "Ying Xiao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "HUANG Wen-jie",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "LIU Zhong-chun",
                "org": "Hubei General Hospital(Wuhan University,Renmin Hospital of Wuhan University),Wuhan,China"
            },
            {
                "name": "Fan Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "中国病毒学(英文版)",
        "year": 2006
    },
    "c50FPHd0": {
        "id": "c50FPHd0",
        "title": "Mapping and Analysis of QTLs on Maternal and Endosperm Genomes for Histidine and Arginine in Rice (Oryza sativa L.) across Environments",
        "abstract": "As a staple cereal crop in the world, rice feeds more than 50% of the world population. The improvement for rice quality including protein content and kinds of amino acid contents is an important work to meet the demands of a growing popula- tion. The genetic analysis on rice indicate that the inheritance of nutrient quality traits is complex, which involve the genetic ef- fects from the triploid endosperm nuclear genes and the diploid maternal plant nuclear genes, being further partitioned into addi- tive and dominance effects, and their genotype × environment (GE) interaction effects. So far, the magnitude and prevalence of interactions between quantitative trait loci (QTL) of the triploid endosperm genome or diploid maternal genome for rice traits are still largely unknown. Therefore, it is necessary to study the genetic main effects and GE interaction effects of the QTL from dif- ferent genomes across environments. Investigations to identify QTL governing histidine (His) and arginine (Arg) contents of rice were conducted using the newly developed QTL mapping method including endosperm and maternal main effects and their GE interaction effects on quantitative traits of seed in cereal crops. Two backcross populations, which were a set of 241 RILs derived from an elite hybrid cross of ‘Shanyou 63’ crossed with ‘Zhenshan 97’ (BC1F1) or ‘Minghui 63’ (BC2F1), were used in two envi- ronments. The results showed that significant differences were found between the two parents for both quantitative quality traits. His and Arg of rice for Zhenshan 97 were higher than those for Minghui 63. The distributions of phenotypic values for His and Arg in BC1F1 (RILs × P1) and BC2F1 (RILs × P2) populations revealed normal distributions approximately. Both backcross popu- lations also showed varying distributions in 1999 and 2000, implying that both amino acid traits were subjected to the modifica- tion by environments. A total of ten QTL associated with His content were mapped on chromosomes 1, 2, 3, 6, 7, 10, 11, and 12. Significant additive effects (ae and am) of QTL from diploid maternal plant and triploid endosperm were detected for all of these QTL. Two of them were also found to have visible endosperm dominance main effects and five QTL had significant environ- mental interaction effects. A total of eight QTL associated with Arg content of rice were mapped on chromosomes 2, 3, 5, 6, 7, 10, 11, and 12. Significant additive main effects of QTL from both genomes were all detected for all of these QTL. Two of them werealso found to have visible endosperm dominance main effects and two QTL had significant environmental interaction effects. The proportions of phenotypic variation attributable to the total genetic main effects and GE interaction of QTL were 0.147 and 0.055 for His and 0.160 and 0.018 for Arg, respectively. These results showed that the control for His and Arg contents of rice was dis- tributed over several chromosomes and the environmental interaction effects were also important for the performance of these quality traits.",
        "keywords": [
            "Endosperm",
            "Maternal plant",
            "Arginine",
            "Histidine",
            "Envi- ronmental interaction",
            "Rice (Oryza sativa L.)",
            "Quantitative trait loci (QTL)"
        ],
        "authors": [
            {
                "name": "ZHENG Xi",
                "org": " Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , Zhejiang, China"
            },
            {
                "name": "WU Jian-Guo",
                "org": " Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , Zhejiang, China"
            },
            {
                "name": "LOU Xiang-Yang",
                "org": "Department of Psychiatry and Neurobehavioral Sciences; Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22911, USA"
            },
            {
                "name": "XU Hai-Ming",
                "org": " Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , Zhejiang, China"
            },
            {
                "name": "SHI Chun-Hai",
                "org": " Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , Zhejiang, China"
            }
        ],
        "venue": "Acta Agronomica Sinica",
        "year": 2008
    },
    "rDWVZ65p": {
        "id": "rDWVZ65p",
        "title": "Potential Effects of Climate Change on the Distributions of Giant Panda(Ailuropoda Melanoleuca) in China",
        "abstract": "Understanding the effects of climate change on species distribution is crucial for the conservation of biodiversity under the climate change. The effects of climate change on distribution of giant panda (Ailuropoda Melanoleuca)in China was analyzed using the CART (classification and regression tree)model and climate change scenarios of A1,A2,B1 and B2. Results showed that climate change will cause a decrease in current distribution of giant panda. And new distribution or total distribution region of the animal were both the biggest in 1991-2020 among periods of 1991-2020,2021-2050,2051-2080 and 2081-2100,then they would decrease from periods of 1991-2020 to periods of 2081-2100,and they were the highest in A1 scenario and the lowest in B1 Scenario. Additionally,following climate change,the east,northeast and south of current distribution regions of giant panda would reduce,while new regions would mainly expand towards the west of current distribution region of the animal. And distribution regions of giant panda would be fragmented following climate change,and it was highest in period of 2051-2080. Additionally,following climate change,the current distribution region,new distribution region or total distribution region of giant panda was negative correlation with changing in annual mean air temperature and precipitation,and the current distribution,new distribution or total distribution region of the animal all decreased with increasing the annual mean air temperature and precipitation,and the effects of changing the annual mean air temperature were higher than that of changing annual precipitation. Results indicated that climate change will cause a decrease in the current distribution region and a increase in the expanding distribution region of giant panda in the near future,while climate change will cause a decrease expanding distribution region and total distribution region of giant panda following increasing extent of climate change.",
        "keywords": [
            "endangered animal",
            "giant panda",
            "climate change",
            "endangered species",
            "precipitation",
            "air temperature"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": "Chinese Academy of Environmental Science,Beijing , China"
            },
            {
                "name": "LV Jia-jia",
                "org": "Chinese Academy of Environmental Science,Beijing , China"
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2009
    },
    "47n8JiiU": {
        "id": "47n8JiiU",
        "title": "On the accuracy of landscape pattern analysis using remote sensing data",
        "abstract": "Advances in remote sensing technologies have provided practical means for land use and land cover mapping which is critically\n important for landscape ecological studies. However, all classifications of remote sensing data are subject to different kinds\n of errors, and these errors can be carried over or propagated in subsequent landscape pattern analysis. When these uncertainties\n go unreported, as they do commonly in the literature, they become hidden errors. While this is apparently an important issue\n in the study of landscapes from either a biophysical or socioeconomic perspective, limited progress has been made in resolving\n this problem. Here we discuss how errors of mapped data can affect landscape metrics and possible strategies which can help\n improve the reliability of landscape pattern analysis.",
        "keywords": [
            "landscape pattern � land use and land cover maps � classification accuracylandscape metrics � errorsremote sensing",
            "remote sensing"
        ],
        "authors": [
            {
                "name": "Guofan Shao",
                "org": "Purdue University Department of Forestry and Natural Resources 715 West State Street West Lafayette IN 47907-1159 USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University School of Life Sciences & Global Institute of Sustainability Tempe AZ 85287-4501 USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2008
    },
    "tPH2UfDi": {
        "id": "tPH2UfDi",
        "title": "Microarray‑based screening of differentially expressed genes in glucocorticoid‑induced avascular necrosis.",
        "abstract": "The underlying mechanisms of glucocorticoid (GC)‑induced avascular necrosis of the femoral head (ANFH) have yet to be fully understood, in particular the mechanisms associated with the change of gene expression pattern. The present study aimed to identify key genes with a differential expression pattern in GC‑induced ANFH. E‑MEXP‑2751 microarray data were downloaded from the ArrayExpress database. Differentially expressed genes (DEGs) were identified in 5 femoral head samples of steroid‑induced ANFH rats compared with 5 placebo‑treated rat samples. Gene Ontology (GO) and pathway enrichment analyses were performed upon these DEGs. A total 93 DEGs (46 upregulated and 47 downregulated genes) were identified in GC‑induced ANFH samples. These DEGs were enriched in different GO terms and pathways, including chondrocyte differentiation and detection of chemical stimuli. The enrichment map revealed that skeletal system development was interconnected with several other GO terms by gene overlap. The literature mined network analysis revealed that 5 upregulated genes were associated with femoral necrosis, including parathyroid hormone receptor 1 (PTHR1), vitamin D (1,25‑Dihydroxyvitamin D3) receptor (VDR), collagen, type II, α1, proprotein convertase subtilisin/kexin type 6 and zinc finger protein 354C (ZFP354C). In addition, ZFP354C and VDR were identified to transcription factors. Furthermore, PTHR1 was revealed to interact with VDR, and α‑2‑macroglobulin (A2M) interacted with fibronectin 1 (FN1) in the PPI network. PTHR1 may be involved in GC‑induced ANFH via interacting with VDR. A2M may also be involved in the development of GC‑induced ANFH through interacting with FN1. An improved understanding of the molecular mechanisms underlying GC‑induced ANFH may provide novel targets for diagnostics and therapeutic treatment.",
        "keywords": "",
        "authors": [
            {
                "name": "Gangyong Huang",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Yibing Wei",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Guanglei Zhao",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Jun Xia",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Siqun Wang",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Feiyan Chen",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Jie Chen",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            },
            {
                "name": "Jingshen Shi",
                "org": "Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China."
            }
        ],
        "venue": "Molecular medicine reports",
        "year": 2017
    },
    "BykGpXer": {
        "id": "BykGpXer",
        "title": "In memoriamFrank B. Golley (19302006)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Monica G. Turner",
                "org": "University of Wisconsin Department of Zoology Madison WI USA"
            },
            {
                "name": "Gary W. Barrett",
                "org": ""
            },
            {
                "name": "Robert H. Gardner",
                "org": "University of Maryland Center for Environmental Science Appalachian Laboratory Frostburg MD USA"
            },
            {
                "name": "Louis R. Iverson",
                "org": "USDA Forest Service Deleware OH USA"
            },
            {
                "name": "Paul G. Risser",
                "org": "Oklahoma State University Oklahoma City OK USA"
            },
            {
                "name": "John A. Wiens",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University School of Life Sciences & Global Institute of Sustainability Tempe AZ 85287 USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2007
    },
    "0aQBMoMh": {
        "id": "0aQBMoMh",
        "title": "Construction and Expression of Vectors Expressing siRNA",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Zhang Jian-lin",
                "org": ""
            },
            {
                "name": "Wu Kai-lang",
                "org": ""
            },
            {
                "name": "Zhang Xue",
                "org": ""
            },
            {
                "name": "Zhu Ying",
                "org": ""
            },
            {
                "name": "Li Yan",
                "org": ""
            },
            {
                "name": "Zhao Wei-guang",
                "org": ""
            },
            {
                "name": "Wu Jian-guo",
                "org": ""
            }
        ],
        "venue": "Virologica Sinica",
        "year": 2004
    },
    "4LDNgXTT": {
        "id": "4LDNgXTT",
        "title": "Polyantibady Preparation of Cyclooxygenase-2 Protein and Its Expression Analysis in Hepatocellular Carcinoma",
        "abstract": "Expression vector carrying cyclooxygenase-2(COX-2) gene was constructed by inserting the C-terminal 777 bp fraction amplified by PCR into the vector pET-28b(+).The fusion protein was expressed in the form of inclusion body after induction by IPTG in BL21(DE3).Using Ni-NTA chelating column,the fusion protein was highly purified.The polyantibody was prepared by immunizing the rabbits with five injections of the purified protein.ELISA and Western Blotting were performed to test its specificity and sensitivity.Meanwhile,cyclooxygeanse-2 expression was detected in hepatocellular carcinoma and surrounding noncancerous liver tissues by Western Blotting using the antiserum.The polyantibody can recognize cyclooxygease-2 with high specificity and sensitivity and cyclooxygenase-2 was expressed at higher level in hepatocellular carcinoma compared to that in surrounding noncancerous liver tissues.Preparation of cyclooxygeanse-2 polyantibody make it possible to further study the biological functions.",
        "keywords": [
            "cyclooxygenase-2 gene",
            "antiserum preparation",
            "prokaryotic expression",
            "hepatocellular carcinoma"
        ],
        "authors": [
            {
                "name": "GU Chunfang",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "MENG Jia",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "WU Jianguo",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            },
            {
                "name": "ZHU Ying",
                "org": "College of Life Sciences,Wuhan University/State Key Laboratory of Virology,Wuhan ,Hubei,China"
            }
        ],
        "venue": "Journal of Wuhan University(Natural Science Edition)",
        "year": 2006
    },
    "4PPBPEn8": {
        "id": "4PPBPEn8",
        "title": "Putative tumor suppressor YueF affects the functions of hepatitis B virus X protein in hepatoma cell apoptosis and p53 expression.",
        "abstract": "Previously, we identified YueF as a novel Hepatitis B virus X protein (HBx)-interacting protein. Herein, we studied the functions of YueF and HBx in hepatocarcinogenesis. YueF was expressed at high levels in normal human hepatic cells and tissues, but scarcely found in hepatoma cells or other tumor tissues. Over-expression of YueF, or YueF and HBx could induce cell apoptosis and enhance p53 expression in hepatoma cells, whereas over-expression of HBx alone behaved contrarily. These results indicate that YueF has tumor suppressor activity and affects the functions of HBx in cell apoptosis and p53 expression in hepatoma cells.",
        "keywords": [
            "Apoptosis",
            "Hepatitis B virus X protein",
            "p53",
            "Tumor suppressor",
            "YueF"
        ],
        "authors": [
            {
                "name": "Jing Huang",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            },
            {
                "name": "Jianlin Zhang",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            },
            {
                "name": "Wei Si",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P.R. China"
            }
        ],
        "venue": "Biotechnology letters",
        "year": 2008
    },
    "SBpTnROJ": {
        "id": "SBpTnROJ",
        "title": "Research on the association of blood hypercoaguable state with acute myocardiac infarct in patients",
        "abstract": "Objective To investigate the correlation of indicators of blood hypercoaguable state and homorheology with the state of disease in patients with acute myocardiac infarct.Mothods Samples from 35 patients with acute myocardiac infarct(AMI),25 patients with acute chest pain but non-AMI and 30 healthy controls were examined for the levels of fibrinogen(FIB),expression of CD62p,protein C(PC),d-dimer(D-D),whole blood viscosity and red cell aggregation index(RAgI).Results The levels of FIB,expression of CD62p,D-D,whole blood viscosity and RAgI were much higher in patients with AMI than those in patients with chest pain but non-AMI and controls.The levels of FIB,expression of CD62p and D-D in finally-dead patients were higher but lower in recovering patients with AMI significantly than those in patients with AMI in acute phage.The levels of FIB,expression of CD62p,D-D and indicators of homorheologic in recovering patients were much higher than those in controls.Excluding PC,other indicators in patients with outbreak of AMI over 6 hours,high FIB and expression of CD62p were significantly higher than those in the corresponding patients with normal levels of those indicators.The levels of PC had significantly opposite change with that of other indicators.Both D-D and the combination of CD62p,PC and FIB had a highest sensitivity of 100.0% in evaluation of hypercoagulable state.The second was all the combinations including CD62p and PC of 91.5%.There was a significantly positive correlation among the levels of D-D,CD62p,FIB,and RAgI one another,and a significantly negative correlation between one of them and PC.Conclusion AMI is closely associated with Hypercoagulable state.Activated platelet,low level of PC and hyper-fibrinogenemia are the more important factors to cause hypercoagulable state in patients with AMI.It is important for D-D to evaluate disease state,therapeutic effect and prognosis in patients with AMI.",
        "keywords": [
            "protein C",
            "activated platelet",
            "d-dimer",
            "Acute myocardiac infarct",
            "hypercoagulable state"
        ],
        "authors": [
            {
                "name": "FEI Xian-ming",
                "org": "Clinical Laboratory canter,People's Hospital of Zhejiang Province Zhejiang Hangzhou ,China"
            },
            {
                "name": "JIANG Lei",
                "org": "Clinical Laboratory canter,People's Hospital of Zhejiang Province Zhejiang Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Clinical Laboratory canter,People's Hospital of Zhejiang Province Zhejiang Hangzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Laboratory Diagnosis",
        "year": 2008
    },
    "HZPjTw9W": {
        "id": "HZPjTw9W",
        "title": "A Biomimetic Nanodecoy Traps Zika Virus to Prevent Viral Infection and Fetal Microcephaly Development.",
        "abstract": "Zika virus (ZIKV) has emerged as a global health threat due to its unexpected causal link to devastating neurological disorders such as fetal microcephaly. However, to date, no approved vaccine or specific treatment is available for ZIKV infection. Here, we develop a biomimetic nanodecoy (ND) that can trap ZIKV, divert ZIKV away from its intended targets, and inhibit ZIKV infection. The ND, which is composed of a gelatin nanoparticle core camouflaged by mosquito medium host cell membranes, effectively adsorbs ZIKV and inhibits ZIKV replication in ZIKV-susceptible cells. Using a mouse model, we demonstrate that NDs significantly attenuate the ZIKV-induced inflammatory responses and degenerative changes and thus improve the survival rate of ZIKV-challenged mice. Moreover, by trapping ZIKV, NDs successfully prevent ZIKV from passing through physiologic barriers into fetal brain and thereby mitigate ZIKV-induced fetal microcephaly in pregnant mice. We anticipate that this study will provide new insights on the development of safe and effective protection against ZIKV and various other viruses that threaten public health.",
        "keywords": "",
        "authors": [
            {
                "name": "Lang Rao",
                "org": ""
            },
            {
                "name": "Wenbiao Wang",
                "org": ""
            },
            {
                "name": "Qian-Fang Meng",
                "org": ""
            },
            {
                "name": "Mingfu Tian",
                "org": ""
            },
            {
                "name": "Bo Cai",
                "org": ""
            },
            {
                "name": "Yingchong Wang",
                "org": ""
            },
            {
                "name": "Aixin Li",
                "org": ""
            },
            {
                "name": "Minghui Zan",
                "org": ""
            },
            {
                "name": "Feng Xiao",
                "org": ""
            },
            {
                "name": "Lin-Lin Bu",
                "org": ""
            },
            {
                "name": "Geng Li",
                "org": ""
            },
            {
                "name": "Andrew Li",
                "org": ""
            },
            {
                "name": "Yingle Liu",
                "org": ""
            },
            {
                "name": "Shi-Shang Guo",
                "org": ""
            },
            {
                "name": "Xing-Zhong Zhao",
                "org": ""
            },
            {
                "name": "Tza-Huei Wang",
                "org": ""
            },
            {
                "name": "Wei Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Nano letters",
        "year": 2018
    },
    "PNdVd8lS": {
        "id": "PNdVd8lS",
        "title": "Three-dimensional finite element analysis of pelvis loaded by transient stress and its biomechanical significance",
        "abstract": "Objective:To explore the mechanical behavior of pelvis loaded by transient stress and provide the mechanical basis for analyzing and judging pelvic fracture classification and mechanical distribution and transient stress affection in clinics.Methods:By means of computer simulation,reading input from reconstructed pelvic three-dimensional model into three-dimensional finite element analysis software ANSYS 7.0,calculated the pelvic mechanical behavior and analyzed the main stress value,stress distribution and pelvic unit displacement in the direction of main stress when unilateral anterior superior iliac spine and unilateral positive backside of ilium was loaded by transient stress,the stress region was 0-8 000 N,peak value was 8 000 N,time range was from 0 ms to 40 ms.Results:When unilateral anterior superior iliac spine loaded by transient stress,0-10 ms,stress distributed from posterior superior iliac spine to anterior superior iliac spine,and on the last 10 ms,there were greater stress distribution around cacroiliac joint,acetabulum and pubic branch.When unilateral positive backside of ilium loaded,between 0 ms and 20 ms,stress transmitted along vertical direction of ilium,and after 20 ms,there were greater stress distribution on cacroiliac joint,both pubic branch,ischium branch and acetabulum.Conclusion:Analyzing the stress distribution of pelvis and units displacement when transient stress was loaded,can provide internal fixation point for treatment of pelvic fracture and further understanding the stress distribution of pelvis.",
        "keywords": [
            "Pelvis",
            "Impulsive load",
            "Element analysis",
            "Biomechanics"
        ],
        "authors": [
            {
                "name": "SU Jia-can",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "GUAN Hua-peng",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "ZHANG Chun-cai",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "CHEN Xue-qiang",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "WANG Bao-hua",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            },
            {
                "name": "DING Zu-quan",
                "org": ".Department of Orthopaedics,the Affiliated Changhai Hospital of the Second Military Medical University,Shanghai ,China"
            }
        ],
        "venue": "China Journal of Orthopaedics and Traumatology",
        "year": 2007
    },
    "elMPVMKR": {
        "id": "elMPVMKR",
        "title": "Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways.",
        "abstract": "Hepatitis C virus (HCV) infection is associated with numerous liver diseases and causes serious global health problems, but the mechanisms underlying the pathogenesis of HCV infections remain largely unknown. In this study, we demonstrate that signal transducer and activator of transcription 3 (STAT3), matrix metalloproteinase-2 (MMP-2), and B-cell lymphoma 2 (Bcl-2) are significantly stimulated in HCV-infected patients. We further show that HCV activates STAT3, MMP-2, Bcl-2, extracellular regulated protein kinase (ERK), and c-Jun N-terminal kinase (JNK) in infected Huh7.5.1 cells. Functional screening of HCV proteins revealed that nonstructural protein 4B (NS4B) is responsible for the activation of MMP-2 and Bcl-2 by stimulating STAT3 through repression of the suppressor of cytokine signaling 3 (SOCS3). Our results also demonstrate that multiple signaling cascades, including several members of the protein kinase C (PKC) family, JNK, ERK, and STAT3, play critical roles in the activation of MMP-2 and Bcl-2 mediated by NS4B. Further studies revealed that the C-terminal domain (CTD) of NS4B is sufficient for the activation of STAT3, JNK, ERK, MMP-2, and Bcl-2. We also show that amino acids 227 to 250 of NS4B are essential for regulation of STAT3, JNK, ERK, MMP-2, and Bcl-2, and among them, three residues (237L, 239S, and 245L) are crucial for this regulation. Thus, we reveal a novel mechanism underlying HCV pathogenesis in which multiple intracellular signaling cascades are cooperatively involved in the activation of two important cellular factors, MMP-2 and Bcl-2, in response to HCV infection.",
        "keywords": [
            "polymerase chain reaction",
            "plasmids",
            "dna primers",
            "signal transduction",
            "china",
            "real time polymerase chain reaction",
            "gene expression regulation"
        ],
        "authors": [
            {
                "name": "Youxing Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qi Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yin Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhen Luo",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Lei Kang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jing Qu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xueshan Xia",
                "org": "Kunming University of Science and Technology(Kunming University of Science and Technology),Kunming,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of virology",
        "year": 2012
    },
    "Cv2gkYrW": {
        "id": "Cv2gkYrW",
        "title": "Engineering of N-glycosylation of hepatitis C virus envelope protein E2 enhances T cell responses for DNA immunization.",
        "abstract": "N-linked oligosaccharides are known to be important in modulating immunogenicity of some viral proteins. However, the roles of N-glycans of hepatitis C virus (HCV) E2 envelope glycoprotein in specific cellular immune responses remain elusive. Previous studies showed that the epitopes aa481-500 and aa551-570 of E2 might be important for immunoreactivity and that the binding site of E2 for hCD81 is located at aa480-493 and aa544-551 within the E2 protein. Here, we made plasmids containing genes encoding either wild type or mutant E2 proteins in which N-glycosylation sites (N560NT and N576ST) close to these important regions were mutated separately or in combination. The immunogenicities of wild type E2 and three mutated E2 proteins were analyzed in BALB/c mice using DNA vaccination. The E2-M2 mutant (at N576ST) significantly enhanced (compared to control) E2-specific CTL activity (P<0.05), expression of IFN-gamma (P<0.05) and suppression of tumor growth (P<0.05). Also, high IgG2a/IgG1 ratios were elicited in a Th1-type response. These results indicate that engineering of the N-glycosylation site N576ST of HCV E2 protein enhances specific cellular immune responses, providing insights into the development of E2-based DNA vaccines with enhanced immunogenicity.",
        "keywords": [
            "envelope protein e2",
            "glycosylation",
            "hepatitis c virus",
            "immune response",
            "dna vaccine",
            "binding site",
            "glycoprotein",
            "wild type",
            "virus"
        ],
        "authors": [
            {
                "name": "Pingfei Li",
                "org": ""
            },
            {
                "name": "Qi Wan",
                "org": "State Key Laboratory of Virology, Department of Immunology and Hubei Province Key Laboratory of Allergy and Immunology, Wuhan University School of Medicine, Wuhan 430071, PR China"
            },
            {
                "name": "Yong Feng",
                "org": "State Key Laboratory of Virology, Department of Immunology and Hubei Province Key Laboratory of Allergy and Immunology, Wuhan University School of Medicine, Wuhan 430071, PR China"
            },
            {
                "name": "Min Liu",
                "org": "State Key Laboratory of Virology, Department of Immunology and Hubei Province Key Laboratory of Allergy and Immunology, Wuhan University School of Medicine, Wuhan 430071, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, Department of Immunology and Hubei Province Key Laboratory of Allergy and Immunology, Wuhan University School of Medicine, Wuhan 430071, PR China"
            },
            {
                "name": "Xinwen Chen",
                "org": "Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China"
            },
            {
                "name": "Xiao-Lian Zhang",
                "org": ""
            }
        ],
        "venue": "Vaccine",
        "year": 2007
    },
    "jPjQFowH": {
        "id": "jPjQFowH",
        "title": "Extraction of peanut skin total polyphenols by microwave combined-Assisted ethanol method",
        "abstract": "Objective:Peanut skin is a by-product of peanut milk from peanut,and it is rich in antioxidants such as polyphenoles.The paper aimed to obtain the optimum extraction conditions of peanut skin total polyphenoles by microwave combined-assisted ethanol method.Methods:Ratio of stuff to solvent,concentration of ethanol,extraction time and the power of microwave were designed to obtained the range of the parameters to the effect on extraction of the polyphenoles,then the experiments based on four factors orthogonal design were further to optimize the extraction conditions.The content of the ployphenoles were determined by UV of gallic acid.Conclusion:The optimum technic parameters were obtained that ratio of stuff to solvent was 1:25,and concentration of ethanol was 75%,and extraction time was 2 mins,and the power of microwave was 540W,and the extraction rate of the total ployphenoles in peanut skin was reached to 183.25±8.62mg/g after five experiments under the optimum technic parameters.",
        "keywords": [
            "microwave",
            "extraction",
            "peanut skin",
            "total polyphenols"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan "
            },
            {
                "name": "CHEN Kan",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan "
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan "
            }
        ],
        "venue": "China Food Additives",
        "year": 2010
    },
    "v01IfId2": {
        "id": "v01IfId2",
        "title": "Research on Cigarette Filter Rod Counting System Based on Machine Vision.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Hongjun Qu",
                "org": ""
            },
            {
                "name": "Peijian Zhang",
                "org": ""
            },
            {
                "name": "Kun Zhang",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "LSMS/ICSEE",
        "year": 2017
    },
    "SH8D2Dna": {
        "id": "SH8D2Dna",
        "title": "Simulation of metal stamping based on the dynamic explicit algorithm",
        "abstract": "The dynamic explicit algorithm applied in simulation of metal forming is formulized in this paper.By means of this algorithm delivered by Dynaform software,the dynamic simulations for the stamping of the oil tank and the cover of micro-motor are carried out.It confirms that the dynamic explicit algorithm is reliable for the metal stamping simulation of large or complicated work-pieces.",
        "keywords": [
            "finite element",
            "dynamic explicit algorithm",
            "simulation of metal forming"
        ],
        "authors": [
            {
                "name": "WANG Yan-hui",
                "org": "Depactment of Mechanical & Electrical Engineering,Shazhou Institute of Technology,Zhangjiagang,Jiangsu ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Depactment of Mechanical & Electrical Engineering,Shazhou Institute of Technology,Zhangjiagang,Jiangsu ,China"
            }
        ],
        "venue": "Forging & Stamping Technology",
        "year": 2006
    },
    "q4Oli56h": {
        "id": "q4Oli56h",
        "title": "Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor.",
        "abstract": "RNA silencing is a potent antiviral response in plants. As a counterdefense, most plant and some animal viruses encode RNA silencing suppressors. In this study, we showed that Pns6, a putative movement protein of Rice ragged stunt virus (RRSV), exhibited silencing suppressor activity in coinfiltration assays with the reporter green fluorescent protein (GFP) in transgenic Nicotiana benthamiana line 16c. Pns6 of RRSV suppressed local silencing induced by sense RNA but had no effect on that induced by dsRNA. Deletion of a region involved in RNA binding abolished the silencing suppressor activity of Pns6. Further, expression of Pns6 enhanced Potato virus × pathogenicity in N. benthamiana. Collectively, these results suggested that RRSV Pns6 functions as a virus suppressor of RNA silencing that targets an upstream step of the dsRNA formation in the RNA silencing pathway. This is the first silencing suppressor to be identified from the genus Oryzavirus.",
        "keywords": [
            "binding sites",
            "protein binding",
            "rna interference",
            "rna silencing",
            "virology",
            "green fluorescent protein",
            "defence mechanisms",
            "transgenic plants",
            "disease resistance",
            "gene expression",
            "genetic engineering",
            "pathogenicity",
            "plant viruses",
            "gene silencing",
            "genetic transformation",
            "rna",
            "genes"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China|Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing China"
            },
            {
                "name": "Zhenguo Du",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China"
            },
            {
                "name": "Chunzheng Wang",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing China"
            },
            {
                "name": "Lijun Cai",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China"
            },
            {
                "name": "Meiqun Hu",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China"
            },
            {
                "name": "Qiying Lin",
                "org": ""
            },
            {
                "name": "Zujian Wu",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China"
            },
            {
                "name": "Yi Li",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing China"
            },
            {
                "name": "Lianhui Xie",
                "org": "Institute of Plant Virology, Fujian Agriculture and Forestry University , Key Laboratory of Plant Virology of Fujian Province, Fuzhou, Fujian, China"
            }
        ],
        "venue": "Virology journal",
        "year": 2010
    },
    "5cxc6sPx": {
        "id": "5cxc6sPx",
        "title": "Improving experimental teaching facilities and opening up of laboratories in order to raise experimental teaching quality of genetics]",
        "abstract": "Advanced teaching facilities and the policy of opening laboratories to students play an important role in raising the quality in the experimental teaching of Genetics. This article introduces the superiority of some advanced instruments and equipment (such as digital microscope mutual laboratory system, flow cytometry, and NIRSystems) in the experimental teaching of genetics, and illustrates with examples the significance of exposing students to experiments in developing their creative consciousness and creative ability. This article also offers some new concepts on the further improvement upon teaching in the laboratory.",
        "keywords": [
            "experiment in genetics",
            "creative consciousness",
            "opening experiment",
            "teaching facilities",
            "creative ability"
        ],
        "authors": [
            {
                "name": "Jian-Fu Xiao",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            },
            {
                "name": "Chun-Hai Shi",
                "org": " Agronomy Department,Zhejiang University,Hangzhou ,China"
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2011
    },
    "JDXEy5LR": {
        "id": "JDXEy5LR",
        "title": "Aptamers that preferentially bind type IVB pili and inhibit human monocytic-cell invasion by Salmonella enterica serovar typhi.",
        "abstract": "Salmonella enterica serovar Typhi is an important pathogen exclusively for humans and causes typhoid or enteric fever. It has been shown that type IVB pili, encoded by the S. enterica serovar Typhi pil operon located in Salmonella pathogenicity island 7, are important in the pathogenic process. In this study, by using both an adhesion-invasion assay and fluorescence quantitative PCR analysis, we demonstrated that the entry of type IVB piliated S. enterica serovar Typhi A21-6 (pil(+) Km(r)) into human THP-1 monocytic cells was greater than that of a nonpiliated S. enterica serovar Typhi pilS::Km(r) (pil mutant) strain. We have applied a systematic evolution of ligands by exponential enrichment approach to select oligonucleotides (aptamers) as ligands that specifically bind to type IVB pili. Using this approach, we identified a high-affinity single-stranded RNA aptamer (S-PS(8.4)) as a type IVB pilus-specific ligand and further found that the selected aptamer (S-PS(8.4)) could significantly inhibit the entry of the piliated strain (but not that of the nonpiliated strain) into human THP-1 cells. The binding affinities between aptamers and pre-PilS (structural protein of type IVB pili) were determined by nitrocellulose filter-binding assays, and the K(d) value was determined to be 8.56 nM for the S-PS(8.4) aptamer alone. As an example of an aptamer against type IVB pili of S. enterica serovar Typhi, the aptamer S-PS(8.4) can serve as a tool for analysis of bacterial type IVB pilus-host cell interactions and may yield information for the development of putative new drugs against S. enterica serovar Typhi bacterial infections, useful both in prevention of infection and in therapeutic treatment.",
        "keywords": [
            "oligonucleotides",
            "binding affinity",
            "public health",
            "ligands",
            "n terminal",
            "protein binding",
            "typhoid fever"
        ],
        "authors": [
            {
                "name": "Qin Pan",
                "org": ""
            },
            {
                "name": "Xiao-Lian Zhang",
                "org": ""
            },
            {
                "name": "Hong-Yan Wu",
                "org": ""
            },
            {
                "name": "Pan-Wen He",
                "org": ""
            },
            {
                "name": "Fubin Wang",
                "org": ""
            },
            {
                "name": "Ming-Sheng Zhang",
                "org": ""
            },
            {
                "name": "Jian-Ming Hu",
                "org": ""
            },
            {
                "name": "Bing Xia",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Antimicrobial agents and chemotherapy",
        "year": 2005
    },
    "QxfwysEK": {
        "id": "QxfwysEK",
        "title": "Modelling epistatic effects of embryo and endosperm QTL on seed quality traits.",
        "abstract": "Coordinated expression of embryo and endosperm tissues is required for proper seed development. The coordination among these two tissues is controlled by the interaction between multiple genes expressed in the embryo and endosperm genomes. In this article, we present a statistical model for testing whether quantitative trait loci (QTL) active in different genomes, diploid embryo and triploid endosperm, epistatically affect a trait expressed on the endosperm tissue. The maximum likelihood approach, implemented with the EM algorithm, was derived to provide the maximum likelihood estimates of the locations of embryo- and endosperm-specific QTL and their main effects and epistatic effects. This model was used in a real example for rice in which two QTL, one from the embryo genome and the other from the endosperm genome, exert a significant interaction effect on gel consistency on the endosperm. Our model has successfully detected Waxy, a candidate gene in the embryo genome known to regulate one of the major steps of amylose biosynthesis in the endosperm. This model will have great implications for agricultural and evolutionary genetic research.",
        "keywords": [
            "embryos"
        ],
        "authors": [
            {
                "name": "Yuehua Cui",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Chunhai Shi",
                "org": ""
            },
            {
                "name": "Ramon C Littell",
                "org": ""
            },
            {
                "name": "Rongling Wu",
                "org": ""
            }
        ],
        "venue": "Genetical research",
        "year": 2006
    },
    "anE9JFID": {
        "id": "anE9JFID",
        "title": "Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.",
        "abstract": "A switch in gene expression from MAT1A to MAT2A was found in liver cancer, suggesting that MAT2A plays an important role in facilitating cancer growth. MAT2A is an interesting target for antineoplastic therapy. The molecular mechanisms of silencing MAT2A by RNA interference inhibited cell growth and induced apoptosis in hepatoma cells was studied.We investigated the effects of MAT2A on S-adenosyl-methionine (SAM) production, cell growth and apoptotic cell death in hepatoma cell lines (Bel-7402, HepG2, and Hep3B) using an RNA interference approach.The treatment of three hepatoma cell lines with small interfering RNA (siRNA) targeting to the MAT2A gene resulted in reducing the MAT II activity, facilitating SAM production, increasing SAM : SAH ratio, inhibiting cell growth and inducing cell apoptosis in hepatoma cells. In addition, silencing MAT2A gene resulted in the stimulation of MAT1A mRNA production, which was blocked by 3-deazaadenosine and l-ethionine, but not d-ethionine, suggesting that such effect was specific and mediated by upregulation of SAM level and SAM : S-adenosylethionine (SAH) ratio.Silencing MAT2A by sequence-specific small interfering RNA caused a switch of MAT gene expression from MAT2A to MAT1A, which led the content of SAM to change to a higher steady-state level that resulted in the inhibition of cell growth and the induction of apoptotic cell death in human hepatoma cells. These results also suggested that MAT2A may hold potential as a new target for liver cancer gene therapy.",
        "keywords": [
            "methionineadenosyl transferase",
            "sirna",
            "cytotoxicity",
            "liver cancer",
            "proliferation",
            "cell growth",
            "rna interference"
        ],
        "authors": [
            {
                "name": "Quanyan Liu",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Yueming He",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Zhisu Liu",
                "org": ""
            }
        ],
        "venue": "Hepatology research : the official journal of the Japan Society of Hepatology",
        "year": 2007
    },
    "Vb3siY1E": {
        "id": "Vb3siY1E",
        "title": "P1.03-16 Anlotinib Inhibits Angiogenesis of Refractory Advanced Non-Small Cell Lung Cancer via Blocking CCL2 Expression",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "J. Lu",
                "org": ""
            },
            {
                "name": "H. Zhong",
                "org": ""
            },
            {
                "name": "T. Chu",
                "org": ""
            },
            {
                "name": "Xueyan Zhang",
                "org": ""
            },
            {
                "name": "Rong Li",
                "org": ""
            },
            {
                "name": "J. Sun",
                "org": ""
            },
            {
                "name": "R. Zhong",
                "org": ""
            },
            {
                "name": "Yang Y",
                "org": ""
            },
            {
                "name": "M.S. Alam",
                "org": ""
            },
            {
                "name": "Y. Lou",
                "org": ""
            },
            {
                "name": "J. Xu",
                "org": ""
            },
            {
                "name": "Y. Zhang",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "Xia Li",
                "org": ""
            },
            {
                "name": "X. Zhao",
                "org": ""
            },
            {
                "name": "K. Li",
                "org": ""
            },
            {
                "name": "L. Lu",
                "org": ""
            },
            {
                "name": "B. Han",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2018
    },
    "sXSTPTbA": {
        "id": "sXSTPTbA",
        "title": "Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.",
        "abstract": "We previously reported that IL-27, which belongs to the IL-12 family of cytokines, is elevated in the serum of patients infected with influenza A virus (IAV). Here, we show that the expression of IL-27 was significantly up-regulated in A549 human lung epithelial cells and human peripheral blood mononuclear cells infected with IAV. Additionally, IAV triggered IL-27 expression through protein kinase A and cAMP-response element-binding protein signaling, which was mediated by cyclooxygenase-2-derived prostaglandin E(2). IL-27 inhibited IAV replication by STAT1/2/3 phosphorylation and activated antiviral factor protein kinase R phosphorylation. Clinical analysis showed that IL-27 levels were significantly elevated in a cohort of patients infected with IAV compared with healthy individuals and that circulating IL-27 levels were tightly and positively correlated with prostaglandin E(2) levels. These results indicate that IL-27 expression is one host immune factor produced in response to IAV infection and that elevated IL-27 levels inhibit viral replication.",
        "keywords": [
            "interleukins",
            "enzyme activation",
            "binding sites",
            "cell line",
            "phosphorylation",
            "case control studies",
            "virus replication",
            "signal transduction"
        ],
        "authors": [
            {
                "name": "Li Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Zhongying Cao",
                "org": ""
            },
            {
                "name": "Jing Chen",
                "org": ""
            },
            {
                "name": "Rui Li",
                "org": ""
            },
            {
                "name": "Yanhua Cao",
                "org": ""
            },
            {
                "name": "Chengliang Zhu",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Fang Liu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            }
        ],
        "venue": "The Journal of biological chemistry",
        "year": 2012
    },
    "kUxkLK8e": {
        "id": "kUxkLK8e",
        "title": "Amino acids 1 to 422 of the spike protein of SARS associated coronavirus are required for induction of cyclooxygenase-2.",
        "abstract": "The causative agent of severe acute respiratory syndrome (SARS) has been identified as SARS-associated coronavirus (SARS-CoV). To evaluate the molecular mechanisms involved in the viral infection, in this study, we investigated the role of SARS-CoV Spike (S) protein in the regulation of cyclooxygenase-2 (COX-2). Expression of COX-2 stimulated by the S protein was verified by RT-PCR and western blot assay. To explore the relationship between S and COX-2, we constructed a series of plasmids containing truncated N-terminal fragments of the SARS-CoV S gene (designated from Sa to Si), which encoded truncated S proteins, and investigated whether these truncated proteins could induce effective expression of COX-2 in 293T cells. Our results showed that S(d) that encoded a truncated S protein with 422 amino acid residues (from 1 to 422 aa), a part of 672 amino-acid S1 subunit is crucial for the induction of COX-2 expression. Immunofluorescence examinations also give the evidence that these N terminal 422 amino acids of the S protein were also required for the correct localization of the protein. We also compared S protein sequences of SARS-CoV isolated during the SARS break with that from palm civets, a possible source of SARS-CoV found in humans. S protein residues (344, 360), which mutated in the epitome from palm civet to human being were characterized in 3D modeling of 252-375 amino acid fragment. Collectively, these results indicate that S protein of SARS-CoV induces the expression of COX-2 and an N-terminal fragment of the Spike protein is crucial for the induction. Our finding may provide clue for the induction of inflammation by SARS-CoV and cast insight into the severity of the SARS epidemic.",
        "keywords": [
            "sars-cov æ spike æ cyclooxygenase-2",
            "SARS-CoV",
            "Spike",
            "Cyclooxygenase-2"
        ],
        "authors": [
            {
                "name": "Mo Liu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P. R. China Wuhan 430072 P. R. China"
            },
            {
                "name": "Chunfang Gu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P. R. China Wuhan 430072 P. R. China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P. R. China Wuhan 430072 P. R. China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 P. R. China Wuhan 430072 P. R. China"
            }
        ],
        "venue": "Virus genes",
        "year": 2006
    },
    "8zQCXlWq": {
        "id": "8zQCXlWq",
        "title": "Genetic analysis of developmental behavior for amylose content in filling process of rice",
        "abstract": "",
        "keywords": [
            "amylose content",
            "correlation coefficients",
            "developmental genetics",
            "genetic variances and conditional genetic variances",
            "heritability",
            "indica rice (oryza sativa l)",
            "quality"
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ping Wu",
                "org": ""
            }
        ],
        "venue": "Journal of The Science of Food and Agriculture",
        "year": 2005
    },
    "MAVEqPQU": {
        "id": "MAVEqPQU",
        "title": "Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine: \"Adenovirus Vaccine Within an Adenovirus Vector\".",
        "abstract": "Human adenoviruses (HAdVs) are highly contagious and result in large number of acute respiratory disease (ARD) cases with severe morbidity and mortality. Human adenovirus type 3 (HAdV-3) is the most common type that causes ARD outbreaks in Asia, Europe, and the Americas. However, there is currently no vaccine approved for its general use. The hexon protein contains the main neutralizing epitopes, provoking strong and lasting immunogenicity. In this study, a novel recombinant and attenuated adenovirus vaccine candidate against HAdV-3 was constructed based on a commercially-available replication-defective HAdV-5 gene therapy and vaccine vector. The entire HAdV-3 hexon gene was integrated into the E1 region of the vector by homologous recombination using a bacterial system. The resultant recombinants expressing the HAdV-3 hexon protein were rescued in AD293 cells, identified and characterized by RT-PCR, Western blots, indirect immunofluorescence, and electron microscopy. This potential vaccine candidate had a similar replicative efficacy as the wild-type HAdV-3 strain. However, and importantly, the vaccine strain had been rendered replication-defective and was incapable of replication in A549 cells after more than twenty-generation passages in AD293 cells. This represents a significant safety feature. The mice immunized both intranasally and intramuscularly by this vaccine candidate raised significant neutralizing antibodies against HAdV-3. Therefore, this recombinant, attenuated, and safe adenovirus vaccine is a promising HAdV-3 vaccine candidate. The strategy of using a clinically approved and replication-defective HAdV-5 vector provides a novel approach to develop universal adenovirus vaccine candidates against all the other types of adenoviruses causing ARDs and perhaps other adenovirus-associated diseases.",
        "keywords": [
            "Adenovirus vaccine",
            "Human adenovirus type 3 (HAdV-3)",
            "Immunity in BALB/c mice",
            "Recombination",
            "Replication-deficient adenovirus vector"
        ],
        "authors": [
            {
                "name": "Yuqian Yan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Shuping Jing",
                "org": "Microbiological Laboratory, Zhuhai Center for Disease Control and Prevention, Zhuhai, 519000, China."
            },
            {
                "name": "Liqiang Feng",
                "org": "Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China."
            },
            {
                "name": "Jing Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China."
            },
            {
                "name": "Zhiwei Zeng",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Min Li",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Shan Zhao",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Junxian Ou",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Wendong Lan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Wenyi Guan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Xiaowei Wu",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China."
            },
            {
                "name": "Donald Seto",
                "org": "Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VA, 20110, USA."
            },
            {
                "name": "Qiwei Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, 510632, China. zhangqw@smu.edu.cn."
            }
        ],
        "venue": "Virologica Sinica",
        "year": 2020
    },
    "M5bBJhnt": {
        "id": "M5bBJhnt",
        "title": "Study on the Preparation Process of the Composite Aluminium Foam Reinforced by Ceramic Spheres",
        "abstract": "The aluminium foam can be reinforced by compositing high hardness ZrO2 ceramic spheres.By improving the die and optimizing the parameters,the precursor made of the salt particals and ceramic spheres and the infiltration process were used to prepare the aluminium foam sample reinforced by ZrO2 ceramic spheres successfully.The optimum process parameters under the condition of experiment were as follows:the prouing temperature of 805 ℃～815 ℃(aluminium)and(silicon-aluminium alloy)of 760 ℃～770 ℃ and the preheating temperature of die and filler of 600 ℃～-610 ℃(aluminium)and 560 ℃～570 ℃(silicon-aluminium alloy),the samples with the dimension of φ30×50mm and ceramic sphere of φ1mm and scale of 1:5 and 2:3 were fabricated.All of these should establish a basement to promote the deeper study and developmenter of composite foamed material.",
        "keywords": [
            "infiltration process",
            "composite material",
            "ZrO2 ceramic sphere",
            "aluminium foam"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science & Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Lu-cai",
                "org": "College of Materials Science and Engineering,Taiyuan University of Science & Technology,Taiyuan Shanxi ,China"
            }
        ],
        "venue": "Foundry Equipment and Technology",
        "year": 2010
    },
    "cxkMQO05": {
        "id": "cxkMQO05",
        "title": "Identification of Pns12 as the second silencing suppressor of <Emphasis Type=\"Italic\">Rice gall dwarf virus</Emphasis>",
        "abstract": "RNA silencing is a conserved mechanism found ubiquitously in eukaryotic organisms. It has been used to regulate gene expression\n and development. In addition, RNA silencing serves as an important mechanism in plants’ defense against invasive nucleic acids,\n such as viruses, transposons, and transgenes. As a counter-defense, most plants, and some animal viruses, encode RNA silencing\n suppressors to interfere at one or several points of the silencing pathway. In this study, we showed that Pns12 of RGDV (Rice gall dwarf virus) exhibits silencing suppressor activity on the reporter green fluorescent protein in transgenic Nicotiana benthamiana line 16c. Pns12 of RGDV suppressed local silencing induced by sense RNA but had no effect on that induced by dsRNA. Expression\n of Pns12 also enhanced Potato virus X pathogenicity in N. benthamiana. Collectively, these results suggested that RGDV Pns12 functions as a virus suppressor of RNA silencing, which might target\n an upstream step of dsRNA formation in the RNA silencing pathway. Furthermore, we showed that Pns12 is localized mainly in\n the nucleus of N. benthamiana leaf cells.",
        "keywords": [
            "Rice gall dwarf virus",
            " Pns12",
            " silencing suppressor"
        ],
        "authors": [
            {
                "name": "JianGuo Wu",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            },
            {
                "name": "ChunZheng Wang",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences,Peking University,Beijing,China"
            },
            {
                "name": "ZhengGuo Du",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            },
            {
                "name": "LiJun Cai",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            },
            {
                "name": "MeiQun Hu",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            },
            {
                "name": "ZuJian Wu",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            },
            {
                "name": "Yi Li",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences,Peking University,Beijing,China"
            },
            {
                "name": "LianHui Xie",
                "org": "Institute of Plant Virology,Fujian Agriculture and Forestry University, Key Laboratory of Plant Virology of Fujian Province,Fuzhou,China"
            }
        ],
        "venue": "Science China. Life sciences",
        "year": 2011
    },
    "Y7Y6WYBf": {
        "id": "Y7Y6WYBf",
        "title": "Predicting the toxicity of unknown chemicals based on gSpan algorithm",
        "abstract": "The graph-based substructure pattern mining algorithm called gSpan,which discovers frequent substructures without candidate generation,is introduced first.gSpan builds a new lexicographic order among graphs and maps each graph to a unique minimum DFS code as its canonical label.Based on this lexicographic order,gSpan adopts the depth-first search strategy to mine frequent connected subgraphs efficiently.When it is applied to the chemical compound dataset Chemical-340,gSpan can find the compound set with same substructure as a chemical compound with toxicity,and then the toxicity of unknown chemicals can be predicted.This study is important to the related fields.",
        "keywords": [
            "frequent subgraph",
            "chemical compound",
            "toxicity prediction"
        ],
        "authors": [
            {
                "name": "XIE Ying",
                "org": "Key Lab of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Lab of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Key Lab of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "XU Rong-bin",
                "org": "Key Lab of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Journal of Hefei University of Technology(Natural Science)",
        "year": 2007
    },
    "3a2w3B0V": {
        "id": "3a2w3B0V",
        "title": "A New Method for the Control of the Conditioning Temperature of Hoop Standard Granulator",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yuan xue",
                "org": "nantong university"
            },
            {
                "name": "jianguo wu",
                "org": "nantong university"
            },
            {
                "name": "lei qin",
                "org": "nantong university"
            },
            {
                "name": "jin liu",
                "org": "nantong university"
            },
            {
                "name": "kun zhang",
                "org": "queen s university belfast"
            }
        ],
        "venue": "international conference on intelligent computing",
        "year": 2014
    },
    "dOvPCfRH": {
        "id": "dOvPCfRH",
        "title": "Direct calculation analysis on structure strength of the water swimming pool",
        "abstract": "The water swimming pool is composed of four steel structure piece bodies that are connected by the bolts,which is different from irregular structure of common ships.In this paper,the equivalent design wave method is used to calculate the wave loads.Corresponding to each wave load which is matched with the most unfavorable deck live load,ballast and hydrostatic load,five computing working conditions are constituted.Finally,stresses of entire ship structure and connecting bolts are calculated based on the self-balancing technology of finite element.",
        "keywords": [
            "irregular structure",
            "direct hydrodynamical calculation",
            "direct structural calculation"
        ],
        "authors": [
            {
                "name": "RUAN Xue-chu",
                "org": "Hangzhou Ship Survey,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "YU Dong-fang",
                "org": "School of Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "NIU Si-bin",
                "org": "School of Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Ship & Boat",
        "year": 2013
    },
    "d7UUZx6V": {
        "id": "d7UUZx6V",
        "title": "Hepatitis B virus-induced calreticulin protein is involved in IFN resistance.",
        "abstract": "IFN-α is a widely used treatment for hepatitis B virus (HBV) infection, and IFN resistance caused by viral and/or host factors is currently a challenging clinical problem. A better understanding of the molecular mechanisms underlying IFN immunotherapy in the treatment of viral infection would be very beneficial clinically and is of immense clinical importance. Calreticulin (CRT) is an endoplasmic reticulum luminal calcium-binding chaperone that is involved in the regulation of calcium homoeostasis, the folding of newly synthesized proteins, and many other cellular functions. However, little is known about the role of CRT in HBV infection. In this study, we observed high levels of CRT expression in the sera and PBMCs of patients with HBV relative to those of healthy individuals. HBV upregulated the expression of CRT at the transcriptional level. Further investigation showed that HBV-induced CRT enhanced HBV replication by antagonizing the IFN pathway. CRT suppressed the production of endogenous IFN-α by reducing the nuclear translocation of IFN regulatory factor-7 but not IFN regulatory factor-3. Furthermore, CRT also suppressed the antiviral activity of IFN-α by inhibiting the phosphorylation of STAT1 and decreasing the expression of two IFN-α downstream effectors, protein kinase R and 2',5'-oligoadenylate synthetase. Our results offer new insights into the pathogenesis of HBV infection and may provide potential targets for anti-HBV therapy.",
        "keywords": [],
        "authors": [
            {
                "name": "Xin Yue",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Hui Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fanpeng Zhao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Shi Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wendan Ren",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Journal of immunology (Baltimore, Md. : 1950)",
        "year": 2012
    },
    "QYXeJ7rW": {
        "id": "QYXeJ7rW",
        "title": "Emergence of RBD mutations in circulating SARS-CoV-2 strains enhancing the structural stability and human ACE2 receptor affinity of the spike protein",
        "abstract": "A novel coronavirus SARS-CoV-2 is associated with the current global pandemic of Coronavirus Disease 2019 (COVID-19). Spike protein receptor-binding domain (RBD) of SARS-CoV-2 is the critical determinant of viral tropism and infectivity. To investigate whether the mutations in the RBD have altered the receptor binding affinity and caused these strains more infectious, we performed molecular dynamics simulations of the binding affinity between the mutant SARS-CoV-2 RBDs to date and the human ACE2 receptor. Among 1609 genomes of global SARS-CoV-2 strains, 32 non-synonymous RBD mutants were identified and clustered into 9 mutant types under high positive selection pressure. Three mutant types (V367F, W436R, and D364Y) emerging in Wuhan, Shenzhen, Hong Kong, and France, displayed higher human ACE2 affinity, and probably higher infectivity. This is due to the enhanced structural stabilization of the RBD beta-sheet scaffold. High frequencies of RBD mutations were identified: V367F from five France and one Hong Kong mutants, 13 V483A and 7 G476S mutants from the U.S.A. This suggested they originated as novel sub-lineages. The enhancement of the binding affinity of the mutant type (V367F) was further validated by the receptor-ligand binding ELISA assay. The molecular dynamics simulations also indicated that it would be difficult for bat SARS-like CoV to infect humans. However, the pangolin CoV is potentially infectious to humans. The analysis of critical RBD mutations provides further insights into the evolutionary history of SARS-CoV-2 under high selection pressure. An enhancement of the SARS-CoV-2 binding affinity to human ACE2 receptor reveals higher infectivity of the mutant strains.  Importance A novel coronavirus SARS-CoV-2 has caused the pandemic of COVID-19. The origin of SARS-CoV-2 was associated with zoonotic infections. The spike protein receptor-binding domain (RBD) is identified as the critical determinant of viral tropism and infectivity. Thus, whether the mutations in the RBD of the circulating SARS-CoV-2 strains have altered the receptor binding affinity and caused these strains more infectious, should be paid more attentions to. Here, 32 non-synonymous RBD mutants were identified and clustered into 9 mutant types under high positive selection pressure, suggesting they originated as novel sub-lineages. Three mutant types displayed higher human ACE2 affinity, and probably higher infectivity, one of which (V367F) was validated by wet bench. The RBD mutation analysis provides insights into SARS-CoV-2 evolution. The emergence of RBD mutations with increased human ACE2 affinity reveals higher risk of severe morbidity and mortality during a sustained COVID-19 pandemic, particularly if no effective precautions are implemented.",
        "keywords": [
            "SARS-CoV-2",
            "ACE2",
            "RBD",
            "spike glycoprotein protein",
            "mutations",
            "infectivity",
            "receptor binding dynamics"
        ],
        "authors": [
            {
                "name": "Junxian Ou",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China"
            },
            {
                "name": "Zhonghua Zhou",
                "org": "Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China"
            },
            {
                "name": "Ruixue Dai",
                "org": "Fudan University Department of Environmental Science and Engineering"
            },
            {
                "name": "Jing Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, Guangdong 510632, China"
            },
            {
                "name": "Wendong Lan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China"
            },
            {
                "name": "Shan Zhao",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, Guangdong 510632, China"
            },
            {
                "name": "Donald Seto",
                "org": "Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VA 20110, USA"
            },
            {
                "name": "Lilian Cui",
                "org": "Novoprotein Scientific Inc"
            },
            {
                "name": "Gong Zhang",
                "org": "Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China"
            },
            {
                "name": "Qiwei Zhang",
                "org": "Southern Medical University"
            }
        ],
        "venue": "bioRxiv",
        "year": 2020
    },
    "IFJgiqeU": {
        "id": "IFJgiqeU",
        "title": "Inhibition of West Nile Virus replication by retrovirus-delivered small interfering RNA in human neuroblastoma cells.",
        "abstract": "West Nile virus (WNV) has been responsible for the largest outbreaks of arboviral encephalitis in U.S. history. No specific drug is currently available for the effective treatment of WNV infection. To exploit RNA interference as a potential therapeutic approach, a Moloney murine leukemia virus-based retrovirus vector was used to effectively deliver WNV-specific small interfering RNA (siRNA) into human neuroblastoma HTB-11 cells. Viral plaque assays demonstrated that transduced cells were significantly refractory to WNV replication, as compared to untransduced control cells (P < 0.05), which correlated with the reduced expression of target viral genes and respective viral proteins. Therefore, retrovirus-mediated delivery of siRNA for gene silencing can be used to study the specific functions of viral genes associated with replication and may have potential therapeutic applications.",
        "keywords": [
            "gene therapy",
            "retroviral vector",
            "small interfering rna (sirna)",
            "wnv",
            "small interfering rna"
        ],
        "authors": [
            {
                "name": "Yongbo Yang",
                "org": ""
            },
            {
                "name": "Chengxiang Wu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Vivek R Nerurkar",
                "org": ""
            },
            {
                "name": "Richard Yanagihara",
                "org": ""
            },
            {
                "name": "Yuanan Lu",
                "org": ""
            }
        ],
        "venue": "Journal of medical virology",
        "year": 2008
    },
    "BghC6U1m": {
        "id": "BghC6U1m",
        "title": "How does habitat fragmentation affect the biodiversity and ecosystem functioning relationship",
        "abstract": "The relationship between biodiversity and ecosystem functioning (BEF) has been a central topic in ecology for more than 20 years. While experimental and theoretical studies have produced much knowledge of how biodiversity affects ecosystem functioning, it remains poorly understood how habitat fragmentation affects the BEF relationship.",
        "keywords": [
            "Complementarity effect",
            " Ecosystem properties",
            " Environment conditions",
            " Functional traits",
            " Habitat fragmentation",
            " Non-random loss"
        ],
        "authors": [
            {
                "name": "Jiajia Liu",
                "org": "Zhejiang University"
            },
            {
                "name": "Maxwell C. Wilson",
                "org": "Arizona State University"
            },
            {
                "name": "Guang Hu",
                "org": "Zhejiang Sci-Tech University"
            },
            {
                "name": "Jinliang Liu",
                "org": "Zhejiang University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University"
            },
            {
                "name": "Mingjian Yu",
                "org": ""
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2018
    },
    "noFuDWuv": {
        "id": "noFuDWuv",
        "title": "Silencing of MAT2A Gene by RNA Interference Resulted in Induction of Apoptosis in Human Hepatoma Cells",
        "abstract": "To investigate the effect of MAT2A on growth and apoptosis of hepatoma cells by small interfering RNA (siRNA) targeting the gene, the expression vector pSilence-2.1-U6-siRNA were constructed and short interfering RNA (siRNA) against MAT2A gene was expressed, effects of siRNAs on the expression of MAT2A gene and protein and on the enzymatic activity of the protein were determined by RT-PCR, Western blot, and activity assays, respectively. Effects of siRNAs on cell growth and apoptosis of hepatoma cell lines Bel-7402, HepG2, and Hep3B were evaluated by MTT method, FACS analysis, and fluorescent microscopy examination. The changes in SAM level and the ratio of SAM∶SAH were measured by reverse-phase high performance liquid chromatography(RP_HPLC). Effects of siRNAs on the expression of MAT1A gene were determined by RT-PCR. The effective siRNA molecules targeting the MAT2A gene were identified that could specific knock-downed MAT2A expression. The MAT activity was decreased after siRNA but not control siRNA treatment in hepatoma cells at 48 hours after transfection and lasted for at least 3 days. This resulted in a great increased SAM content and the ratio of SAM to SAH in hepatoma cells. A switch in the gene expression from MAT2A to MAT1A has been found in hepatoma cells with siRNA. Furthermore, silencing of the MAT2A gene by RNAi significantly inhibited hepatoma cell growth and eventually lead to induction of apoptosis. A greater apoptosis response was observed in siRNA transfected cells than control cells (P<0.05). Staining of the nuclear DNA of effective siRNA transfected cells with DAPI reveled nuclear fragmentation and chromatin condensation; otherwise, typical hallmarks of apoptosis were not detected in control cells. The results demonstrated that RNA interference-mediated silencing of MAT2A gene inhibited growth and induced apoptosis of human hepatoma cells and suggested that MAT2A was a suitable target for RNA interference, which holds great potentials for specific gene therapy of liver cancer.",
        "keywords": [
            "MAT2A",
            "siRNA",
            "apoptosis",
            "hepatoma"
        ],
        "authors": [
            {
                "name": "LIU Quan-Yan",
                "org": ""
            },
            {
                "name": "LIU Zhi-Su",
                "org": ""
            },
            {
                "name": "WU Kai-Lang",
                "org": " ~ 2) Key Laboratory of Virology, Ministry of Education, College of Life Sciences, Wuhan University, Wuhan ,China )"
            },
            {
                "name": "ZHU Ying",
                "org": " ~ 2) Key Laboratory of Virology, Ministry of Education, College of Life Sciences, Wuhan University, Wuhan ,China )"
            },
            {
                "name": "HE Yue-Ming",
                "org": ""
            },
            {
                "name": "WU Jian-Guo",
                "org": " ~ 2) Key Laboratory of Virology, Ministry of Education, College of Life Sciences, Wuhan University, Wuhan ,China )"
            }
        ],
        "venue": "Chinese Journal of Biochemistry and Molecular Biology",
        "year": 2006
    },
    "YNCnWtJF": {
        "id": "YNCnWtJF",
        "title": "Shear Buckling Analysis for Simply Supported Plate Panel with Larger Opening",
        "abstract": "So far,there is lack of solution for shear buckling on simply supported plate panel with larger opening in current Common Structural Rule(CSR).This paper shows how to seek the solution by non-linear FEA method trying to obtain the elastic and plastic shear buckling capacities on sets of simply supported plate panels with larger opening.The outcome can be introduced in the CSR in the future.",
        "keywords": [
            "CSR rule",
            "Shear buckling",
            "Ultimate bearing capacity",
            "Plate panel with large opening"
        ],
        "authors": [
            {
                "name": "WANG Jian-zhong",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "HONG Ying",
                "org": "China Classification Society Shanghai Institute,Shanghai ,China"
            },
            {
                "name": "CHU Yan-ling",
                "org": "China Classification Society Shanghai Institute,Shanghai ,China"
            },
            {
                "name": "Wu Jian-guo",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Marine Technology",
        "year": 2012
    },
    "hh6qEMhw": {
        "id": "hh6qEMhw",
        "title": "Rice Stripe Mosaic Virus-encoded P4 Is A Weak Suppressor of Viral RNA Silencing and is Required for Disease Symptom Development.",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Chao Zhang",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China"
            },
            {
                "name": "Dong Chen",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China"
            },
            {
                "name": "Guoyi Yang",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China"
            },
            {
                "name": "Xiyuan Yu",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Institute of Plant Virology, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, 350002, China"
            }
        ],
        "venue": "Molecular Plant-microbe Interactions",
        "year": 2020
    },
    "apUErHp0": {
        "id": "apUErHp0",
        "title": "Improving the writing of research papers: IMRAD and beyond",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ, 85287, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2011
    },
    "FK4LkFAB": {
        "id": "FK4LkFAB",
        "title": "Coronavirus Infections and Immune Responses",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Geng Li",
                "org": "Guangdong Provincial Key Laboratory of Virology Institute of Medical Microbiology, Jinan University Guangzhou 510632 China"
            },
            {
                "name": "Yaohuao Fan",
                "org": "First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Yanni Lai",
                "org": "First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Tiantian Han",
                "org": "First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Zonghui Li",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Peiwen Zhou",
                "org": "Guangdong Provincial Key Laboratory of Virology Institute of Medical Microbiology, Jinan University Guangzhou 510632 China"
            },
            {
                "name": "Pan Pan",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Wenbiao Wang",
                "org": "Guangdong Provincial Key Laboratory of Virology Institute of Medical Microbiology, Jinan University Guangzhou 510632 China"
            },
            {
                "name": "Dingwen Hu",
                "org": "State Key Laboratory of Virology College of Life Sciences, Wuhan University Wuhan 430072 China"
            },
            {
                "name": "Xiaohong Liu",
                "org": "First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou 510405 China"
            },
            {
                "name": "Qiwei Zhang",
                "org": "Southern Medical University Guangzhou 510515 China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology Institute of Medical Microbiology, Jinan University Guangzhou 510632 China"
            }
        ],
        "venue": "Journal of Medical Virology",
        "year": 2020
    },
    "0X4cWAYP": {
        "id": "0X4cWAYP",
        "title": "The screening of mutants and construction of mutant library for Oryza sativa cv. Nipponbare via ethyl methane sulphonate inducing",
        "abstract": "Following the sequencing of rice genome, the functional analysis of unidentified genes is gaining wide importance. Mutant isolation is one of the effective ways to isolate and clone the target genes and analyze their functions. To find the various mutants in the same genetic background, seeds of Oryza sativa cv. Nipponbare were treated with ethyl methane sulphonate (EMS). A total of 1056 mutants were screened for five categories in M2 generation with the seedling frequency of 26.29‰ at three-leaf stage, but only 264 mutants were verified in M3 generation with a frequency of 6.57‰. Among the mutants verified in M3 generation, the frequency of leaf mutation was the highest (2.22‰), followed by seedling height (1.74‰) and the abiotic stress tolerance mutant (147‰). Nineteen characteristic mutations, including a big group of abiotic stress tolerant mutants such as herbicide resistant, salt tolerant and drought tolerant were identified at this stage. By observation of rice growth characteristics at different developmental stages, another 220 mutants have been isolated and verified in the M3 generation with the mutant frequency of 53.9‰ covering about 28 mutant traits. Among those identified, the highest frequencies were obtained for appearance of brown rice mutant with 18.37‰, followed by panicle mutant with 13.47‰, and grain mutants with 9.06‰. All the mutants screened above were suitable for gene function analysis and for utilization in agronomy. © 2010 Versita Warsaw and Springer-Verlag Wien.",
        "keywords": [
            "Ethyl methane sulphonate (EMS)",
            "Inducing",
            "Mutagenesis",
            "Oryza sativa cv. Nipponbare",
            "Rice"
        ],
        "authors": [
            {
                "name": "Nguyen B. Thang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Weihui Zhou",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Biologia",
        "year": 2010
    },
    "8Z2i7Ya4": {
        "id": "8Z2i7Ya4",
        "title": "Impacts of future urban expansion on summer climate and heat-related human health in eastern China.",
        "abstract": "China is the largest and most rapidly urbanizing nation in the world, and is projected to add an additional 200 million city dwellers by the end of 2030. While this rapid urbanization will lead to vast expansion of built-up areas, the possible climate effect and associated human health impact remain poorly understood. Using a coupled urban-atmospheric model, we first examine potential effects of three urban expansion scenarios to 2030 on summer climate in eastern China. Our simulations indicate extensive warming up to 5°C, 3°C, and 2°C in regard to low- (>0%), high- (>75%), and 100% probability urban growth scenarios, respectively. The partitioning of available energy largely explains the changes in 2-m air temperatures, and increased sensible heat flux with higher roughness length of the underlying urban surface is responsible for the increase of nighttime planetary boundary layer height. In the extreme case (the low-probability expansion pathway), the agglomeration of impervious surfaces substantially reduces low-level atmospheric moisture, consequently resulting in large-scale precipitation reduction. However, the effect of near-surface warming far exceeds that of moisture reduction and imposes non-negligible thermal loads on urban residents. Our study, using a scenario-based approach that accounts for the full range of urban growth uncertainty by 2030, helps better evaluate possible regional climate effects and associated human health outcomes in the most rapidly urbanizing areas of China, and has practical implications for the development of sustainable urban regions that are resilient to changes in both mean and extreme conditions.",
        "keywords": [
            "China",
            "Climate change",
            "Health impact",
            "Urbanization",
            "WRF"
        ],
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China. Electronic address: ydy@bnu.edu.cn."
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning, Urban Climate Research Center, Arizona State University, Tempe, AZ 85287, United States."
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China; School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ 85287, United States. Electronic address: Jingle.Wu@asu.edu."
            },
            {
                "name": "Wei Wang",
                "org": "Mesoscale & Microscale Meteorology Laboratory, National Center for Atmospheric Research, Boulder, CO 80301, United States."
            }
        ],
        "venue": "Environment international",
        "year": 2017
    },
    "vAbU5s7X": {
        "id": "vAbU5s7X",
        "title": "Critical Discourse Analysis:Review and Prospect",
        "abstract": "Accompanied with the 'linguistic turn' in social theory and the 'discursive turn' in linguistics,critical discourse analysis plays a more and more important role in social research.With this in mind,the authors of this paper firstly give a review of the basic tenets,historical origin,theoretical bases,and research methods of critical discourse analysis(CDA),and then they point out some prospective research directions in this field.It is hoped that this will shed some light on our understanding of CDA.",
        "keywords": [
            "theoretical basis",
            "prospect",
            "critical discourse analysis",
            "review",
            "research method"
        ],
        "authors": [
            {
                "name": "XU Ying",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,"
            }
        ],
        "venue": "Journal of South China University of Technology(Social Science Edition)",
        "year": 2013
    },
    "wSRsckcp": {
        "id": "wSRsckcp",
        "title": "Impact Factors of Heat Dissipation of Foamed Magnesium",
        "abstract": "The heat dissipation of foamed magnesium was investigated through orthogonal experiment.The influence of porosity and pore size on the cooling effect was studied.Experimental results showed that cooling effect related to pore structure,the pore size has the greatest effect,porosity second.The cooling effect achieved the best when pore size is 2.2 mm ～3.2 mm,porosity70%,thickness 35 mm.",
        "keywords": [
            "heat dissipation",
            "forced convection",
            "porous magnesium"
        ],
        "authors": [
            {
                "name": "WANG Chao-xing",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Fang",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "YOU Xiao-hong",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Lu-cai",
                "org": "School of Material Science and Engineering,Taiyuan University of Science and Technology,Taiyuan Shanxi ,China"
            }
        ],
        "venue": "Foundry Equipment and Technology",
        "year": 2012
    },
    "tvtDF6zw": {
        "id": "tvtDF6zw",
        "title": "Genetic Analysis for Lysine Content of Rapeseed Cake (<I>Brassic napus</I> L.) at Different Periods after Anthesis: Genetic Analysis for Lysine Content of Rapeseed Cake (<I>Brassic napus</I> L.) at Different Periods after Anthesis",
        "abstract": "",
        "keywords": [
            "genetic analysis"
        ],
        "authors": [
            {
                "name": "Guo-Lin CHEN",
                "org": ""
            },
            {
                "name": "Jian-Guo WU",
                "org": ""
            },
            {
                "name": "Li ZHANG",
                "org": ""
            },
            {
                "name": "Chun-Hai SHI",
                "org": ""
            }
        ],
        "venue": "Acta Agronomica Sinica",
        "year": 2010
    },
    "st4g7uRc": {
        "id": "st4g7uRc",
        "title": "STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection.",
        "abstract": "One of the fundamental reactions of the innate immune responses to pathogen infection is the release of pro-inflammatory cytokines, including IL-1β, processed by the NLRP3 inflammasome. The stimulator of interferon genes (STING) has the essential roles in innate immune response against pathogen infections. Here we reveal a distinct mechanism by which STING regulates the NLRP3 inflammasome activation, IL-1β secretion, and inflammatory responses in human cell lines, mice primary cells, and mice. Interestingly, upon HSV-1 infection and cytosolic DNA stimulation, STING binds to NLRP3 and promotes the inflammasome activation through two approaches. First, STING recruits NLRP3 and facilitates NLRP3 localization in the endoplasmic reticulum, thereby facilitating the inflammasome formation. Second, STING interacts with NLRP3 and attenuates K48- and K63-linked polyubiquitination of NLRP3, thereby promoting the inflammasome activation. Collectively, we demonstrate that the cGAS-STING-NLRP3 signaling is essential for host defense against HSV-1 infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Wenbiao Wang",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Dingwen Hu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Caifeng Wu",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Yuqian Feng",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Aixin Li",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingchong Wang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Keli Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Mingfu Tian",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Feng Xiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Muhammad Adnan Shereen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weijie Chen",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Pan Pan",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Pin Wan",
                "org": "Guangdong Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2020
    },
    "OYyyJ4xb": {
        "id": "OYyyJ4xb",
        "title": "MA25.09 Navigating Anlotinib Precision Therapy Through the Genetic Profiling of Circulating DNA in Non-Small Cell Lung Cancer Patients",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "J. Lu",
                "org": ""
            },
            {
                "name": "H. Zhong",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "T. Chu",
                "org": ""
            },
            {
                "name": "L. Zhang",
                "org": ""
            },
            {
                "name": "H. Li",
                "org": ""
            },
            {
                "name": "Q. Wang",
                "org": ""
            },
            {
                "name": "R. Li",
                "org": ""
            },
            {
                "name": "Y. Zhao",
                "org": ""
            },
            {
                "name": "A. Gu",
                "org": ""
            },
            {
                "name": "C. Shi",
                "org": ""
            },
            {
                "name": "L. Xiong",
                "org": ""
            },
            {
                "name": "X. Zhang",
                "org": ""
            },
            {
                "name": "W. Zhang",
                "org": ""
            },
            {
                "name": "Y. Lou",
                "org": ""
            },
            {
                "name": "B. Yan",
                "org": ""
            },
            {
                "name": "Y. Dong",
                "org": ""
            },
            {
                "name": "Y. Zhang",
                "org": ""
            },
            {
                "name": "B. Li",
                "org": ""
            },
            {
                "name": "X. Zhao",
                "org": ""
            },
            {
                "name": "K. Li",
                "org": ""
            },
            {
                "name": "B. Han",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2019
    },
    "cFD4u9Tz": {
        "id": "cFD4u9Tz",
        "title": "Analyzing sustainability of Chinese mining cities using an association rule mining approach",
        "abstract": "Mining cities are of vital importance to the global development, but they are facing great challenges to achieve sustainability goals. Understanding the characteristics and patterns of the environmental, economic, and social conditions of mining cities is critical to promoting their sustainability. After developing an Indicator System for Mining City Sustainability, we collected data from 110 prefecture-level cities and analyzed environmental, economic, and social characteristics of these mining cities using a data-mining method – Association rule mining. Our analysis revealed some novel, implicit, and previously unknown characteristics and patterns of mining city sustainability in China. We found that education investment, economic development, and some aspects of society were substantially unbalanced in most Chinese mining cities. Most coal-mining cites had a larger proportion of mining population, and usually faced severe challenges in reducing industrial dust emission. The unsustainable characteristics of Chinese mining cities exhibited distinctive regional patterns and should be considered explicitly in policy making to promote the sustainability of these urban areas.",
        "keywords": "",
        "authors": [
            {
                "name": "Lijun Zeng",
                "org": "College of Economics and Management, Shandong University of Science and Technology, 579 Qianwangang Road, Qingdao 266590, PR China"
            },
            {
                "name": "Bingcheng Wang",
                "org": "College of Economics and Management, Shandong University of Science and Technology, 579 Qianwangang Road, Qingdao 266590, PR China"
            },
            {
                "name": "Liu Fan",
                "org": "College of Economics and Management, Shandong University of Science and Technology, 579 Qianwangang Road, Qingdao 266590, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            }
        ],
        "venue": "Resources Policy",
        "year": 2016
    },
    "eimFo4kL": {
        "id": "eimFo4kL",
        "title": "Viral infection induces expression of novel phased microRNAs from conserved cellular microRNA precursors.",
        "abstract": "RNA silencing, mediated by small RNAs including microRNAs (miRNAs) and small interfering RNAs (siRNAs), is a potent antiviral or antibacterial mechanism, besides regulating normal cellular gene expression critical for development and physiology. To gain insights into host small RNA metabolism under infections by different viruses, we used Solexa/Illumina deep sequencing to characterize the small RNA profiles of rice plants infected by two distinct viruses, Rice dwarf virus (RDV, dsRNA virus) and Rice stripe virus (RSV, a negative sense and ambisense RNA virus), respectively, as compared with those from non-infected plants. Our analyses showed that RSV infection enhanced the accumulation of some rice miRNA*s, but not their corresponding miRNAs, as well as accumulation of phased siRNAs from a particular precursor. Furthermore, RSV infection also induced the expression of novel miRNAs in a phased pattern from several conserved miRNA precursors. In comparison, no such changes in host small RNA expression was observed in RDV-infected rice plants. Significantly RSV infection elevated the expression levels of selective OsDCLs and OsAGOs, whereas RDV infection only affected the expression of certain OsRDRs. Our results provide a comparative analysis, via deep sequencing, of changes in the small RNA profiles and in the genes of RNA silencing machinery induced by different viruses in a natural and economically important crop host plant. They uncover new mechanisms and complexity of virus-host interactions that may have important implications for further studies on the evolution of cellular small RNA biogenesis that impact pathogen infection, pathogenesis, as well as organismal development.",
        "keywords": [
            "host plant",
            "small interfering rna",
            "real time polymerase chain reaction",
            "microrna",
            "computational biology",
            "comparative analysis",
            "micrornas",
            "rna silencing",
            "gene expression",
            "rna interference"
        ],
        "authors": [
            {
                "name": "Peng Du",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Jiayao Zhang",
                "org": "Renmin University of China(Renmin University of China),Beijing,China"
            },
            {
                "name": "Shuqi Zhao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Hong Zheng",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Ge Gao",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Liping Wei",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Yi Li",
                "org": "Peking University(Peking University),Beijing,China"
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2011
    },
    "T3RvJudY": {
        "id": "T3RvJudY",
        "title": "Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling",
        "abstract": "ABSTRACT  Hepatitis B virus (HBV) infection may cause acute hepatitis B, chronic hepatitis B (CHB), liver cirrhosis, and hepatocellular carcinoma (HCC). However, the mechanisms by which HBV evades host immunity and maintains chronic infection are largely unknown. Here, we revealed that matrix metalloproteinase 9 (MMP-9) is activated in peripheral blood mononuclear cells (PBMCs) of HBV-infected patients, and HBV stimulates MMP-9 expression in macrophages and PBMCs isolated from healthy individuals. MMP-9 plays important roles in the breakdown of the extracellular matrix and in the facilitation of tumor progression, invasion, metastasis, and angiogenesis. MMP-9 also regulates respiratory syncytial virus (RSV) replication, but the mechanism underlying such regulation is unknown. We further demonstrated that MMP-9 facilitates HBV replication by repressing the interferon (IFN)/Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway, IFN action, STAT1/2 phosphorylation, and IFN-stimulated gene (ISG) expression. Moreover, MMP-9 binds to type I IFN receptor 1 (IFNAR1) and facilitates IFNAR1 phosphorylation, ubiquitination, subcellular distribution, and degradation to interfere with the binding of IFANR1 to IFN-α. Thus, we identified a novel positive-feedback regulation loop between HBV replication and MMP-9 production. On one hand, HBV activates MMP-9 in infected patients and leukocytes. On the other hand, MMP-9 facilitates HBV replication through repressing IFN/JAK/STAT signaling, IFNAR1 function, and IFN-α action. Therefore, HBV may take the advantage of MMP-9 function to establish or maintain chronic infection.   IMPORTANCE  Hepatitis B virus (HBV) infection may cause chronic hepatitis B (CHB) and hepatocellular carcinoma (HCC). However, the mechanisms by which HBV maintains chronic infection are largely unknown. Matrix metalloproteinase 9 (MMP-9) plays important roles in the facilitation of tumor progression, invasion, metastasis, and angiogenesis. However, the effects of MMP-9 on HBV replication and pathogenesis are not known. This study reveals that MMP-9 expression is activated in patients with CHB, and HBV stimulates MMP-9 production in PBMCs and macrophages. More interestingly, MMP-9 in turn promotes HBV replication through suppressing IFN-α action. Moreover, MMP-9 interacts with type I interferon receptor 1 (IFNAR1) to disturb the binding of IFN-α to IFNAR1 and facilitate the phosphorylation, ubiquitination, subcellular distribution, and degradation of IFNAR1. Therefore, these results discover a novel role of MMP-9 in viral replication and reveal a new mechanism by which HBV evades host immunity to maintain persistent infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Junbo Chen",
                "org": ""
            },
            {
                "name": "Wei Xu",
                "org": ""
            },
            {
                "name": "Yanni Chen",
                "org": ""
            },
            {
                "name": "Xueping Xie",
                "org": ""
            },
            {
                "name": "Yecheng Zhang",
                "org": ""
            },
            {
                "name": "Chunqiang Ma",
                "org": ""
            },
            {
                "name": "Qingyu Yang",
                "org": ""
            },
            {
                "name": "Yang Han",
                "org": ""
            },
            {
                "name": "Chengliang Zhu",
                "org": ""
            },
            {
                "name": "Ying Xiong",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Fang Liu",
                "org": ""
            },
            {
                "name": "Yingle Liu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Journal of Virology",
        "year": 2017
    },
    "mfUZZthG": {
        "id": "mfUZZthG",
        "title": "Analysis of clinical predictive factors of pathologic complete response after neoadjuvant chemoradiotherapy in rectal cancer]",
        "abstract": "To evaluate the clinical predictive factors associated with pathologic complete response (pCR) after neoadjuvant chemoradiotherapy in rectal cancer.A retrospective analysis was performed on clinical data of 87 patients with rectal cancer, who underwent neoadjuvant chemoradiotherapy followed by radical surgery from April 2007 to May 2015. All patients received pelvic intensity-modulated radiotherapy (50 Gy/25 fractions) with concurrent fluorouracil- based chemotherapy and then underwent radical surgery 4-8 weeks later. The clinical factors associated with pCR or non-pCR were analyzed by Logistic regression.Eighty-three patients had completed treatment, of which 15 patients (18.1%) achieved pCR after neoadjuvant chemoradiotherapy. Univariate analysis showed non-diabetes(P=0.033), pre-chemoradiotherapy plasma glucose(≤6.1 mmol/L)(P=0.033), pre-chemoradiotherapy CEA(≤5 μg/L)(P=0.026), pre- chemoradiotherapy plasma lymphocytes count(≤1.5×10(9)/L)(P=0.042), pre- chemoradiotherapy plasma platelet(≤240×10(12))(P=0.043), tumor pathological type(adenocarcinoma)(P=0.036)were significantly correlated with pCR after neoadjuvant chemoradiotherapy in rectal cancer. Logistic regression revealed that non-diabetes, pre-chemoradiotherapy plasma glucose, pre-chemoradiotherapy CEA(≤5 μg/L), pre-chemoradiotherapy plasma lymphocytes count(≤1.5×10(9)/L), tumor pathological type(adenocarcinoma) were independent predictive factors of pCR after neoadjuvant chemoradiotherapy in rectal cancer.Patients with non-diabetes, normal plasma glucose, normal CEA, lower plasma lymphocytes count and adenocarcinoma were associated with pCR after neoadjuvant chemoradiotherapy for rectal cancer.",
        "keywords": "",
        "authors": [
            {
                "name": "T Yu",
                "org": "Department of General Surgery, Peking University First Hospital, Beijing 100034, China."
            },
            {
                "name": "X L Cao",
                "org": ""
            },
            {
                "name": "G J Wu",
                "org": ""
            },
            {
                "name": "G Zhao",
                "org": ""
            },
            {
                "name": "W W Jia",
                "org": ""
            },
            {
                "name": "G Xiao",
                "org": ""
            },
            {
                "name": "X Wang",
                "org": ""
            }
        ],
        "venue": "Zhonghua yi xue za zhi",
        "year": 2016
    },
    "zzILz3Bf": {
        "id": "zzILz3Bf",
        "title": "A liver-specific microRNA binds to a highly conserved RNA sequence of hepatitis B virus and negatively regulates viral gene expression and replication.",
        "abstract": "Regulated gene expression and progeny production are essential for persistent and chronic infection by human pathogens, such as hepatitis B virus (HBV), which affects >400 million people worldwide and is a major cause of liver disease. In this study, we provide the first direct evidence that a liver-specific microRNA, miR-122, binds to a highly conserved HBV pregenomic RNA sequence via base-pairing interactions and inhibits HBV gene expression and replication. The miR-122 target sequence is located at the coding region of the mRNA for the viral polymerase and the 3' untranslated region of the mRNA for the core protein. In cultured cells, HBV gene expression and replication reduces with increased expression of miR-122, and the expression of miR-122 decreases in the presence of HBV infection and replication. Furthermore, analyses of clinical samples demonstrated an inverse linear correlation in vivo between the miR-122 level and the viral loads in the peripheral blood mononuclear cells of HBV-positive patients. Our results suggest that miR-122 may down-regulate HBV replication by binding to the viral target sequence, contributing to the persistent/chronic infection of HBV, and that HBV-induced modulation of miR-122 expression may represent a mechanism to facilitate viral pathogenesis.",
        "keywords": [
            "mir-122",
            "liver disease",
            "therapeutic agent",
            "viral infection",
            "chronic infection",
            "hepatocellular carcinoma",
            "dna primers",
            "case control studies",
            "down regulation",
            "virus replication",
            "micrornas",
            "conserved sequence"
        ],
        "authors": [
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ao Shen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Paul J Rider",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Yi Yu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Kailang Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yongxin Mu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qian Hao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Hao Gong",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fenyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
        "year": 2011
    },
    "LN38JW2S": {
        "id": "LN38JW2S",
        "title": "Tradeoffs and thresholds in the effects of nitrogen addition on biodiversity and ecosystem functioning: evidence from inner Mongolia Grasslands: IMPACT OF N ENRICHMENT ON ECOSYSTEM FUNCTIONING",
        "abstract": "",
        "keywords": [
            "nitrogen"
        ],
        "authors": [
            {
                "name": "YONGFEI BAI",
                "org": ""
            },
            {
                "name": "JIANGUO WU",
                "org": ""
            },
            {
                "name": "CHRISTOPHER M. CLARK",
                "org": ""
            },
            {
                "name": "SHAHID NAEEM",
                "org": ""
            },
            {
                "name": "QINGMIN PAN",
                "org": ""
            },
            {
                "name": "JIANHUI HUANG",
                "org": ""
            },
            {
                "name": "LIXIA ZHANG",
                "org": ""
            },
            {
                "name": "XINGGUO HAN",
                "org": ""
            }
        ],
        "venue": "Global Change Biology",
        "year": 2010
    },
    "PyS41Y8P": {
        "id": "PyS41Y8P",
        "title": "The soil particulate organic carbon in different elevation and its relationship with vegetation in Qilian Mountain",
        "abstract": "The soil particulate organic matter-carbon (POC) is the unprotected pool of soil organic carbon (SOC) and it would indi- cate the stabilization of SOC. The Qilian mountain located the northern border of Qinghai-Tibet plateau with different vegetation and soil type, the SOC under these vegetations would be changed with change in climate or human being activities, and the SOC with different stabilization would be changed differently by the disturbance. To know the different stabilization of SOC under different altitude and vegetation of this mountain for understanding the impacts of climate change on the alpine ecosystem carbon sink, the POC in different elevation and its relationship with vegetation in Qi Lian Mountain was investigated. The results showed that the ratio of soil particulate fraction decreased with increasing elevation in 0~15 cm and 15~35 cm soil depth(P>0.2), and the ratio of POC in 0~15 cm soil depth decreased with increasing elevation(P≤0.001), while it increased with increasing elevation in 15~30 cm soil depth(P>0.5). Soil particulate fraction in 0~15 cm soil depth under 3 000 m~3 500 m of shady slope or which in 15~35 cm soil depth under 3 200 m or 3 500 m of shady slope or 2 200 m~2 800 m was the highest among different altitudes(P<0.05), and the ratio of POC in 0~15 cm soil depth under 3 000 m and 3 200 m of shady slope or 2 200 m and 2 800 m, or that in 15~35 cm soil depth under 3 200 m and 3 500 m of shady slope or 3 300 m and 3 500 m of sunny slope was also the highest under different alti- tudes(P<0.05). The POC and the carbon content of soil particulate fraction both did not significantly increase with increasing alti- tudes (P<0.9). The difference of the carbon content of soil particulate fraction between 0~15 cm and 15~35 cm soil depth under dif- ferent altitudes except 2 200m ~2 800 m or 3 000 m of shady slope or 3 600 m of sunny slope was not significant (P<0.05). The con- tent of POC in 0~15 cm under 3 000 m~3 500 m of shady slope or that in 15~35 cm under 3 000 m~3 500 m of shady slope or 3300m of sunny slope, and the carbon content of particulate fraction in 0~15cm soil depth under 3 000~3 400 m of shady slope and 3 300 m of sunny slope or that in 15~35 cm under 3 200 m and 3 400 m of shady slope and 3 300 m of sunny slope were the highest among different altitudes(P<0.05). The ratio of soil particulate fraction in 0~15 cm soil depth under forest and shrub alpine meadows were the highest and the difference of this ratio between under forest and shrub meadows or desert steppe and arid steppe was not significant (P<0.05), and that in 15~35 cm soil depth under forest and shrub meadows or arid steppe was the highest among different vegetations (P<0.05). The ratio of POC in 0~15 cm soil depth under desert steppe and arid steppe or that in 15~35 cm soil depth under forest and shrub meadows was also the highest among different vegetations (P<0.05). The carbon content of soil particulate fraction in 0~15 cm and 15~35 cm soil depth under forest and shrub meadows was the highest, and that under desert steppe was the lowest among different vegetations (P<0.05). The POC content in 0~15 cm and 15~35 cm soil depth under forest was the highest among different vegetations (P<0.05), while that between under alpine meadows and arid steppe or desert steppe was not significant (P<0.05). The carbon content of particulate fraction and POC content were significantly positively related to SOC content(P<0.001), and POC content was also significantly positively related to carbon content of particulate fraction (P<0.001),while soil particulate fraction ratio was not significantly positively related to SOC content(P≤0.15). Additionally, the POC content was also significantly positively related to ratio of soil particulate fraction (P<0.005). The results showed that the altitude and vegetation together influ- enced the stabilization of SOC and the stabilization of SOC under arid steppe or desert steppe was lower than that under alpine meadows, while the content of unprotected SOC was higher under forest and shrub meadows than that under other vegetations.",
        "keywords": [
            "soil organic carbon",
            "Qilian mountain",
            "particulate organic carbon"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "Ai Li",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China; Guangzhou Academy of Environmental Protection and Sciences Technology, Guangzhou , China"
            },
            {
                "name": "Tian Ziqiang",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "Chang Xuexiang",
                "org": " Cold And Arid Regions Environment and Engineering Research Institute, Chinese Academy of Science, Lanzhou , China"
            }
        ],
        "venue": "Ecology and Environment",
        "year": 2008
    },
    "nB9MAEKV": {
        "id": "nB9MAEKV",
        "title": "Characteristics and Innovation of a Combination of Industry,Education and Scientific Research in S.I.T.",
        "abstract": "The school-running characteristics of Shazhou Professional Institute of Technology(S.I.T.) are analysed first,model and running mechanism of a combination of industry,education and scientific research in the college are concluded.Many cases about the combination of industry,education and scientific research are studied and then four great innovations in the process of combining the industry,learning and scientific research with education and combining the industry,learning and scientific research with science and technology in the college are elaborated.",
        "keywords": [
            "the leadership of the government",
            "platform of science and technology",
            "overall cooperation",
            "education and scientific research",
            "a combination of industry",
            "industry-oriented"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "YI Shun-ming",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            },
            {
                "name": "WU Hai-ye",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang "
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2007
    },
    "pRlgoPT4": {
        "id": "pRlgoPT4",
        "title": "Recontextualization and Transformation in Media Discourse:An Analysis of Peng Yu Case",
        "abstract": "Enlightened by the previous studies on recontextualization in political discourse,the present paper analyzes recontextualization and transformation in media discourse from the Discourse-Historical-Contextual Approach,which is originated from the integration of van Dijk'scontext model and Wodak's Discourse-Historical Approach.Specifically,the paper explores the context models of the trails,media interpretations,reports,and public interpretations.It also reveals the interdiscursive and intertextual relationships involved in the process of recontextualization.The corresponding transformation devices adopted by the journalist are also examined so as to reveal the interrelationship among recontextualization,transformation,and interpretation.",
        "keywords": [
            "\"Peng Yu Case\"",
            "recontextualization",
            "transformation"
        ],
        "authors": [
            {
                "name": "HUANG Shan-shan",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,"
            }
        ],
        "venue": "Journal of South China University of Technology(Social Science Edition)",
        "year": 2012
    },
    "gtjiQmAK": {
        "id": "gtjiQmAK",
        "title": "Analysis of developmental genetics for phenylalanine content in indica-japonica hybrid rice (Oryza sativa L.) across environments",
        "abstract": "Developmental genetics of phenylalanine content in indica-japonica hybrid rice (Oryza sativa L.) have been studied through 7 indica rice crossed with 5 japonica rice by using the developmental genetic models and corresponding statistical approaches for quantitative traits of triploid seeds in cereal crops. The unconditional genetic model was used to analyze the cumulative genetic effects (from flowering to a specific time) along the developmental stages, and the conditional genetic model was used to analyze the genetic effects in one specially developmental stage from one filling time to another time (t-1→t). Results showed that phenylalanine content of indica-japonica hybrid rice was simultaneously controlled by the triploid endosperm effects, cytoplasm effects, diploid maternal effects and their genotype x environment interaction effects. Endosperm dominance effect, maternal additive effect and cytoplasmic effect were more important at the initial stage of rice development than endosperm additive effect and maternal dominance effect. With regard to the components of heritability, maternal and cytoplasm general heritability and their interaction heritability were higher for phenylalanine content at all 5 developmental stages. Respectively, it occupied 68.3, 92.4, 100.0, 100.0 and 78.9% among all the component of heritability. It was suggested that improving the phenylalanine content of indica-japonica hybrid rice would be more efficient when selection was based on maternal plants at early generations in rice breeding program.",
        "keywords": [
            "conditional genetic variance",
            "developmental genetics",
            "genetic variance",
            "heritability",
            "indica-japonica hybrid rice",
            "phenylalanine content",
            "quality",
            "genetics"
        ],
        "authors": [
            {
                "name": "Xiaoming Zhang",
                "org": "Zhejiang Academy of Agricultural Sciences(Zhejiang Academy of Agricultural Sciences,Zhejiang Academy of Agricultural Science),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Shen H. Yue",
                "org": "Zhejiang Academy of Agricultural Sciences(Zhejiang Academy of Agricultural Sciences,Zhejiang Academy of Agricultural Science),Hangzhou,China"
            },
            {
                "name": "Yongbin Qi",
                "org": "Zhejiang Academy of Agricultural Sciences(Zhejiang Academy of Agricultural Sciences,Zhejiang Academy of Agricultural Science),Hangzhou,China"
            }
        ],
        "venue": "Cereal Research Communications",
        "year": 2006
    },
    "FtgsS6pT": {
        "id": "FtgsS6pT",
        "title": "Morphological characteristics and gene mapping of a dense panicle (dp2) mutant in rice (Oryza sativa L.)",
        "abstract": "A dense panicle mutant (dp2) derived from the Oryza sativa ssp. japonica cultivar Nipponbare through ethyl methane sulfonate mutagenesis was used in present study. Compared to the wild type, the panicle of dp2 mutant exhibited more branches and denser grains. Further more, the number of spikelets per panicle, number of primary branches and secondary branches of dp2 mutant were significantly increased while the panicle length, and 1,000-grain weight were significantly decreased. The results from the genetic analysis indicated that the dense panicle phenotype was controlled by a single dominance nuclear gene. Polymorphic analysis of SSR and InDel markers demonstrated that the DP2 gene was located at the long arm of chromosome 2, which was further mapped between SSR markers RM341 and RM13356 in a physical region of 398 kb. Within this region, the RCN2 (LOC_Os02g32950) gene which was annotated relating to the development of rice panicle was found. Compared to the wild type, the sequence of RCN2 gene in the dp2 mutant showed that two SNPs replacement had taken place in the promoter region (G–A) and the intron region (A–T), respectively. The dp2 mutant could be a novel mutant of RCN2 gene and this novel mutant might be useful for further studies on this gene.",
        "keywords": [
            "Dense panicle 2 (dp2)",
            " Morphological characteristics",
            " Map-based cloning",
            " Rice"
        ],
        "authors": [
            {
                "name": "yunlong yang",
                "org": "zhejiang university"
            },
            {
                "name": "chunhai shi",
                "org": "zhejiang university"
            },
            {
                "name": "yuanfei zhou",
                "org": "zhejiang university"
            },
            {
                "name": "jianguo wu",
                "org": "Department of Horticulture,Zhejiang A&F University,Linan,China"
            },
            {
                "name": "xiaoli jin",
                "org": "zhejiang university"
            },
            {
                "name": "jianyao shou",
                "org": "zhejiang university"
            }
        ],
        "venue": "Genes & Genomics",
        "year": 2014
    },
    "FntgUJPg": {
        "id": "FntgUJPg",
        "title": "Relationship between the Geographic Distribution Patterns of Typical Agricultural and Forest Pest Species with Climatic Factors in China",
        "abstract": "Based on the standard climatic database for the period 1971 to 2000 provided by the National Meteorological Information Center of the China Meteorological Administration,the relationship between the geographical distribution patterns of 70 agricultural and forest pest species with narrow geographic ranges and climatic factors were analyzed by using Arc GIS 9.2 software and correlation analysis methods.The results show that 33 pest species had very narrow geographic ranges.22 of the other 37 pest species were continuously distributed,and 15 species were discontinuously distributed.The majority of the 70 pest species adapted to a habitat with an annual mean temperature of 10-20 ℃,annual sunshine duration of 1500-2500 h,relative humidity of 60%-80% and annual precipitation of 400-1600 mm.Most pest species were adaptable to a mean air temperature range below 20 ℃ and could tolerate extreme air temperatures.Most pest species could adapt to a wide precipitation range,but their adaptation to humidity was relatively narrow.Most pest species lived well in wide range of sunshine hours.There was a significant correlation between richness of pests and annual mean air temperature,annual maximum and minimum air temperature and extreme minimum air temperature(P<0.05).The changing of richness showed a parabolic shape under different climates.The results indicated that the geographical distribution patterns of the 70 pest species were influenced by climatic factors,and the distributions of the different pest species were constrained by the different climatic factors.",
        "keywords": [
            "pests",
            "geographical distribution",
            "climatic factors"
        ],
        "authors": [
            {
                "name": "LI Yan",
                "org": "School of Agriculture,Shenyang Agricultural University,Shenyang ,China;Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "XIE Li-yong",
                "org": "School of Agriculture,Shenyang Agricultural University,Shenyang ,China"
            },
            {
                "name": "ZHOU Qiao-fu",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2012
    },
    "GYznnPTg": {
        "id": "GYznnPTg",
        "title": "Treatment for macular edema after retinal vein occlusion",
        "abstract": "Retinal vein occlusion is a familiar retinal vascular disorder that was frequently associated with severe vision loss due to its complications such as cystoid macular edema(CME) and neovascular glaucoma.The current therapies include macular grid pattern photocoagulation or diffuse retinal photocoagulation,chorioretinal venous anastomosis,surgical decompression,medicine(triam-cinolone acetonide,anti-VEGF factors),etc.This paper reviewed the progress of therapeutic approaches in recent years and achievements of some random control trials.",
        "keywords": [
            "treatment",
            "macular edema",
            "retinal vein occlusion"
        ],
        "authors": [
            {
                "name": "Xiao-Xu Zhou",
                "org": " Department of Medical Experiments,Wuhan General Hospital of Guangzhou Military Command of Chinese PLA,Wuhan ,Hubei Province,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": " Department of Medical Experiments,Wuhan General Hospital of Guangzhou Military Command of Chinese PLA,Wuhan ,Hubei Province,China"
            }
        ],
        "venue": "International Journal of Ophthalmology",
        "year": 2008
    },
    "6QuOJOC7": {
        "id": "6QuOJOC7",
        "title": "Multi-scale analysis of ecosystem service trade-offs in urbanizing drylands of China: A case study in the Hohhot-Baotou-Ordos-Yulin region",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Ze Xiang Sun",
                "org": "Beijing Normal University"
            },
            {
                "name": "Zhifeng Liu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Chunyang He",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, School of"
            }
        ],
        "venue": "Acta Ecologica Sinica",
        "year": 2016
    },
    "bHQdG1DR": {
        "id": "bHQdG1DR",
        "title": "Analysis of genetic effects for heterosis of erucicacid and glucosinolate contents in rapeseed (Brassica napus L.)",
        "abstract": "The embryo, cytoplasmic, and maternal heterosis for erucic acid content (EAC) and glucosinolate content (GLS) of rapeseed (Brassica napus L.) were studied by using the genetic models for quantitative traits of seeds in diploid crops. Eight parents were included in a diallel mating design in two years. It was found that the heterosis of EAC and GLS was simultaneously controlled by genetic main effects and genotypexenvironment (GE) interaction effects. The general heterosis of most crosses for EAC was significantly positive, while it was not for GLS. The general heterosis was more important for two quality traits of rapeseed because of the low GE interaction heterosis in both years, especially for GLS. Among different genetic systems, significant positive embryo general heterosis and the negative maternal general heterosis were found for EAC and GLS in most hybrid crosses. Some hybrids with significant negative interaction heterosis were detected for either of EAC or GLS. In general, maternal general and interaction heterosis was more important for reducing EAC and GLS of rapeseed.",
        "keywords": [
            "rapeseed",
            "quality",
            "general heterosis",
            "GE interaction heterosis"
        ],
        "authors": [
            {
                "name": "HaiZhen Zhang",
                "org": "Zhejiang Univ, Coll Agr & Biotechnol, Dept Agron, Hangzhou 310029, Zhejiang, Peoples R China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang Univ, Coll Agr & Biotechnol, Dept Agron, Hangzhou 310029, Zhejiang, Peoples R China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang Univ, Coll Agr & Biotechnol, Dept Agron, Hangzhou 310029, Zhejiang, Peoples R China"
            }
        ],
        "venue": "AGRICULTURAL SCIENCES IN CHINA",
        "year": 2011
    },
    "SrwMvrSS": {
        "id": "SrwMvrSS",
        "title": "The Function of Mathematics upon Economics Based on the Analysis of Nobel Prize",
        "abstract": "Based on the analysis of the 2003 Nobel economics prize scholarship contribution,the function of mathematic thinking and methods upon the analysis of solving economic problens,the development of economic theory is expounded.",
        "keywords": [
            "economics Nobel Prize mathematics function"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Hunan College of Finance and Economics,Changsha,"
            }
        ],
        "venue": "Mathematical Theory and Application",
        "year": 2005
    },
    "mIxe1ceE": {
        "id": "mIxe1ceE",
        "title": "Asprellcosides B of Ilex asprella Inhibits Influenza A Virus Infection by Blocking the Hemagglutinin- Mediated Membrane Fusion.",
        "abstract": " is routinely used in China as a traditional medicinal herb to treat influenza (Flu). However, its specific antiviral activity and underlying molecular mechanism have not yet been determined. In this study, we sought to determine the antiviral activity and mechanism of Asprellcosides B, an active component extracted from , and used against the influenza A virus cell culture. We also performed a computer-assisted structural modeling analysis and carried out surface plasmon resonance (SPR) experiments in the hope of determining the viral target of Asprellcosides B. Results from our studies show that Asprellcosides B reduced virus replication by up to 63% with an IC50 of about 9 μM. It also decreased the low pH-induced and virus-mediated hemolysis by 71% . Molecular docking simulation analysis suggested a possible binding of Asprellcosides B to the hemagglutinin (HA), which was confirmed by a surface plasmon resonance (SPR) assay. Altogether, our findings demonstrate that Asprellcosides B inhibits the influenza A virus, through a specific binding to the HA, resulting in the blockade of the HA-mediated membrane fusion.",
        "keywords": [
            "Ilex asprella",
            "anti-influenza activity",
            "competitive inhibition",
            "hemagglutinin (HA) protein",
            "inhibition of membrane fusion",
            "triterpenoid saponins sulfate"
        ],
        "authors": [
            {
                "name": "Wen Zhang",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Si-Tai Chen",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Qiu-Yan He",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Li-Quan Huang",
                "org": "The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China."
            },
            {
                "name": "Xiong Li",
                "org": "Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China."
            },
            {
                "name": "Xiao-Ping Lai",
                "org": "Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Traditional Chinese Medicine, Dongguan, China."
            },
            {
                "name": "Shao-Feng Zhan",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Hui-Ting Huang",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Xiao-Hong Liu",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Longfan Biological Science and Technology Company, Ltd., Foshan, China."
            },
            {
                "name": "Geng Li",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            }
        ],
        "venue": "Frontiers in microbiology",
        "year": 2018
    },
    "cQoMgfFd": {
        "id": "cQoMgfFd",
        "title": "Analysis on ultimate strength of bulk carrier by CSR",
        "abstract": "Based on the progressive failure analysis proposed by CSR,this paper adopts self-compiled hull girder ultimate strength calculation software,and calculates various multi-structured ships.The results are similar as many scholars,and are rather close to the results of optimized Bulk carrier calculated by MAC/Marc,with FEM program Partran for modeling.The results indicate that the progressive failure analysis proposed by CSR has high precision.",
        "keywords": [
            "hull girder",
            "ultimate strength",
            "Finite Element Method",
            "bulk carrier",
            "progressive failure analysis method"
        ],
        "authors": [
            {
                "name": "Xiao Feng",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            },
            {
                "name": "Sun Yan",
                "org": ""
            }
        ],
        "venue": "Ship & Boat",
        "year": 2010
    },
    "2QHdRnQg": {
        "id": "2QHdRnQg",
        "title": "Potential Effects of Climate Change on the Distributions of 5 Plants in China",
        "abstract": "The effects of climate change on distributions of 5 species, such as Tsoongiodendron odorum, Liriodendron chinese, Kingdonia uniflora, Boschniakia rossica and Acanthopanax senticosus in China were analyzed using CART (classification and regression tree) model and climate change scenarios of A2 and B2. The results showed that the current distributions of these plants except of T. odorum would decrease under climate change, and the new or total distribution region of T. odorum would increase, while those of other plants decrease. And the reducetions of the current, new or total distribution region of B. rossica and A. senticosus are the highest, then were L. chinese and K. uniflora. T. odorum and L. chinese would distribute towards north of current distribution regions, while K. uniflora towards southwest, and B. rossica and A. senticosus would dissipate at the period of 2081~2100. Moreover, the changes in distribution of these plants inconsistent with those in annual mean temperature and annual precipitation. There were no significant relation (P>0.05) between the annual mean air temperature, precipitation in China and current distribution of T. odorum, also with new or total distribution region of K. uniflora, and did not between the distribution of B. rossica and annual precipitation in China (P>0.05). It indicated that the spatial distribution pattern of these species would change with climate changes.",
        "keywords": [
            "Endangered plant",
            "Spatial distribution pattern",
            "Climate change",
            "CART model"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences, Beijing , China"
            }
        ],
        "venue": "Journal of Tropical and Subtropical Botany",
        "year": 2010
    },
    "Pwr1uzUU": {
        "id": "Pwr1uzUU",
        "title": "Impacts of urban expansion on ecosystem services in the Beijing-Tianjin-Hebei urban agglomeration, China: A scenario analysis based on the Shared Socioeconomic Pathways",
        "abstract": "Abstract   Understanding the impacts of urban expansion on ecosystem services (ESs) is important for sustainable development on regional and global scales. However, due to the uncertainty of future socioeconomic development and the complexity of urban expansion, assessing the impacts of future urban expansion on ESs remains challenging. In this study, we simulated the urban expansion in the Beijing-Tianjin-Hebei (BTH) urban agglomeration in China from 2013 to 2040, and assessed its potential impacts on ESs based on the Shared Socioeconomic Pathways (SSPs) and the Land Use Scenario Dynamics-urban (LUSD-urban) model. We found that urban land in the BTH urban agglomeration is expected to increase from 7605.25 km 2  in 2013 to 9401.75–11,936.00 km 2  in 2040. With continuing urban expansion, food production (FP), carbon storage (CS), water retention (WR), and air purification (AP) will decrease by 1.34–3.16%, 0.68–1.60%, 0.80–1.89%, and 0.37–0.87%, respectively. The conversion of cropland to urban land will be the main cause of ES losses. During 2013–2040, the losses of ESs caused by this conversion will account for 83.66–97.11% of the total losses in the whole region. Furthermore, the ES losses can cause considerable negative impacts on human well-being. The loss of FP will be equivalent to the food requirement of 3.68–8.61% of the total population in 2040, and the loss of CS will be 2.55–6.01% of the total standard coal consumption in 2013. To ensure sustainable development in the region, we suggest that effective policies and regulations should be implemented to protect cropland with high ES values from urban expansion.",
        "keywords": "",
        "authors": [
            {
                "name": "Da Zhang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Qingxu Huang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing 100875, China"
            }
        ],
        "venue": "Resources Conservation and Recycling",
        "year": 2017
    },
    "ervgjw6t": {
        "id": "ervgjw6t",
        "title": "Research of Programming Technology of Chinese Input Method Based on IMM-IME",
        "abstract": "Chinese keyboard input method is an important issue of natural language processing.It runs as a component of Windows multilingual support system and has a different programming technology.A Win32 IME has to provide two components defined by IMM-IME architecture.One is the IME user interface,the other is the IME conversion interface which can convert input keyboard characters into Chinese characters.Provides IMM-IME architecture,work procedure and implementation steps for researchers on related field,which must be mastered while accomplishing Chinese sentence input method.",
        "keywords": [
            "input method editor",
            "natural language processing",
            "Chinese input method"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2006
    },
    "OIbcfr92": {
        "id": "OIbcfr92",
        "title": "Roles of scholars in the practice of combating-desertification: a case study in northwest China.",
        "abstract": "This study investigated the perceived importance of scholars' participation in combating-desertification programs in northwest China and analyzed the underlying factors and mechanisms. Our results show that, while various experts, professors, and researchers have participated in combating-desertification programs, their actions were often not effective. Only those scholars who understood the local situations adequately had important and positive impacts. These scholars served as information brokers between the governments and other stakeholders, entrepreneurial activity organizers for farmers, governmental representatives, or advocators for local affairs themselves. They played indispensible roles in facilitating efforts in combating desertification. The study also identified key factors that led to the success of scholars' participation in combating-desertification activities. Our findings have practical implications for improving the effectiveness of scholars' participation in land restoration and environmental management.",
        "keywords": [
            "Combating desertification",
            "Scholars’ participation",
            "Land amelioration",
            "Mechanisms of scholars’ participation",
            "Environmental management"
        ],
        "authors": [
            {
                "name": "Lihua Yang",
                "org": "School of Public Administration, Beihang University, No. 37 Xueyuan Rd, Beijing, 100191 China"
            },
            {
                "name": "Zhiyong Lan",
                "org": "School of Public Affairs, Arizona State University, 3720 411, North Central Avenue, Ste. 450, Phoenix, AZ 85004-0687, USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ USA"
            }
        ],
        "venue": "Environmental management",
        "year": 2010
    },
    "roIgPGOQ": {
        "id": "roIgPGOQ",
        "title": "Temporal patterns of maternal, cytoplasmic and embryo genetic effects for thousand-seed weight and oil content in F1 hybrid rapeseed (Brassica napus L.)",
        "abstract": "The analysis of temporal patterns of genetic effects for thousand-seed weight (TSW) and oil content (OC) in rapeseed was conducted at five different seed development times using unconditional and conditional genetic models for diploid seed quantitative traits. Phenotypic means among generations and seed development times in 2 different years revealed considerable variation for both TSW and OC. The expression of genes from diploid embryo, cytoplasmic and maternal plant genetic systems were all found to be important for the F 1 generation, with maternal effects playing a more prominent role for both traits at most times. The conditional analysis indicated that the stage-specific gene expression from the maternal plant was influenced by environment. Higher magnitudes of additive and cytoplasmic effects were observed for both traits. Narrow-sense heritability was high for both traits at all developmental times with maternal heritability being more prominent at most times. Genetic correlations between TSW and OC were mostly negative over developmental times. © 2010 CSIRO.",
        "keywords": [
            "brassica napus l.",
            "developmental genetics",
            "genetic correlation",
            "genetic effects",
            "heritability",
            "oil content",
            "rapeseed",
            "seed development",
            "thousand-seed weight.",
            "water use",
            "plant pathology",
            "agronomy",
            "interaction",
            "plant breeding",
            "climate",
            "crop",
            "educational",
            "animal nutrition",
            "sustainable",
            "plant protection",
            "animal breeding"
        ],
        "authors": [
            {
                "name": "Murali Tottekkaad Variath",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yunxia Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Guolin Chen",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Crop and Pasture Science",
        "year": 2010
    },
    "Xt3qEbZ8": {
        "id": "Xt3qEbZ8",
        "title": "Evolutionary genomic analysis for VP1 gene of human enterovirus 71 in Wuhan region of China from 2011 to 2012",
        "abstract": "Objective To investigate the genotypes and the recombination features of human enterovirus 71(EV71) strains from handfoot-mouth disease(HFMD) patients in Wuhan and its surrounding cities from April 2011 to March 2012.Methods The throat swab samples from 1 844 HFMD cases were collected,and 124 EV71-positive strains were isolated.The VP1 gene with 508 bp in EV71 isolates was sequenced.The whole genomes of three EV71 isolates,two from severe cases and one from mild cases,were also sequenced and the phylogenetic tree was constructed to analyze the genomic recombination features.Results Phylofenetic analysis revealed that all the 124 EV71 isolates belonged to subgenotype C4.Among them,56 C4a and 68 C4b isolates were demonstrated.Bootscan and phylofenetic analysis based on the genomic 5'UTR,P1,P2 and P3 regions revealed the recombination at 2A-2B junction of EV 71 P2 region between parent strain C4a(guangdong / GD / CHN /2009) and C4b(SHZH98 / GD / CHN /1998).Conclusion All the studied EV71 isolates in Wuhan and the surrounding cities belonged to subgenotype C4,which was consistent with the preponderant strain prevalent in mainland China since 1998.The intratypic recombination was found in subgenotype C4 of EV71.",
        "keywords": [
            "hand-foot-mouth disease",
            "enterovirus 71",
            "Wuhan",
            "phylogenetic tree"
        ],
        "authors": [
            {
                "name": "WU Shi-min",
                "org": ""
            },
            {
                "name": "XIANG Jie",
                "org": ""
            },
            {
                "name": "ZHOU Hong",
                "org": ""
            },
            {
                "name": "WU Zhi-qiang",
                "org": ""
            },
            {
                "name": "LI Hong-ze",
                "org": ""
            },
            {
                "name": "LIU Wei-yong",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Clinical Laboratory Science",
        "year": 2013
    },
    "yJw8k1Sj": {
        "id": "yJw8k1Sj",
        "title": "Thirty years of Landscape Ecology (1987–2017): retrospects and prospects",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, School of Sustainability, and Julie A. Wrigley Global Institute of Sustainability, Arizona State University, Tempe, USA"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2017
    },
    "rkmlXp71": {
        "id": "rkmlXp71",
        "title": "Relationship of ecosystem primary productivity to species diversity and functional group diversity: evidence from Stipa breviflora grassland in Nei Mongol",
        "abstract": "Aims The relationship between biodiversity and ecosystem functioning has been a central issue in ecology. However, this relationship is poorly understood for the Stipa breviflora grassland, which is a major community type of desert steppe in Nei Mongol. With unpredictably fluctuating climate conditions, these desert steppe ecosystems are fragile and provide a unique opportunity to test our current understanding of the relationship between biodiversity and ecosystem functioning. This study has two objectives: (1) to examine if species diversity and functional group diversity affect ecosystem primary productivity in the desert steppe of Nei Mongol and (2) to explore how resource supply levels affect the relationship between diversity and productivity. Methods Based on life forms, species were classified into five functional groups: shrub and semishrub, perennial bunchgrass, perennial rhizome grass, perennial forb, and annual and biennial. Species richness and functional group richness were used to represent species diversity and functional group diversity, respectively. Based on the dryness coefficient, 202 sites across the S. breviflora grassland in Nei Mongol were sampled, and divided into two resource supply levels: arid and semiarid zones. In order to tease out the effect of precipitation, partial regression analysis and partial correlation analysis were used for exploring the relationship of ecosystem primary productivity to species richness and functional group richness, respectively. According to the determination coefficient of regression analysis, the effect of resource supply levels on the diversity-productivity relationship was evaluated.Important findings Species richness and ecosystem primary productivity were both positively and linearly correlated with precipitation, but no significant correlation was found between functional group richness and precipitation. Ecosystem primary productivity increased significantly with species richness, but not with functional group richness. Resource supply levels could affect the diversity-productivity relationship in that plant species diversity generally had a weaker effect on ecosystem primary productivity at the lower resource supply level and a stronger effect at the higher resource supply level.",
        "keywords": [
            "species richness",
            "functional group richness",
            "resource supply",
            "productivity"
        ],
        "authors": [
            {
                "name": "MA Wen-Jing",
                "org": ""
            },
            {
                "name": "ZHANG Qing",
                "org": " Sino-US Center for Conservation, Energy and Sustainability Science in Inner Mongolia, Hohhot , China"
            },
            {
                "name": "NIU Jian-Ming",
                "org": " Sino-US Center for Conservation, Energy and Sustainability Science in Inner Mongolia, Hohhot , China"
            },
            {
                "name": "KANG Sarula",
                "org": ""
            },
            {
                "name": "LIU Peng-Tao",
                "org": "School of Life Sciences and Global Institute of Sustainability; Inner Mongolia Meteorology Bureau, Hohhot , China"
            },
            {
                "name": "HE Xin",
                "org": ""
            },
            {
                "name": "YANG Yan",
                "org": ""
            },
            {
                "name": "ZHANG Yan-Nan",
                "org": ""
            },
            {
                "name": "WU Jian-Guo",
                "org": "Arizona State University; Sino-US Center for Conservation, Energy and Sustainability Science in Inner Mongolia, Hohhot , China; and 4 School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ, USA 85287"
            }
        ],
        "venue": "Chinese Journal of Plant Ecology",
        "year": 2013
    },
    "UlkOBfSU": {
        "id": "UlkOBfSU",
        "title": "Intensive land-use drives regional-scale homogenization of plant communities.",
        "abstract": "Intensive anthropogenic land-use causes habitat loss and landscape homogenization, which leads to the decrease of biodiversity and ecosystem degradation. Therefore, it is important to study the influence of landscape heterogeneity on biodiversity. In this study, vegetation surveys conducted at 53 sites in the Tabu River basin, located at the agro-pastoral ecotone of Inner Mongolia of China, revealed 146 species. Species diversity was evaluated at three scales: species richness within patches (alpha diversity), between patches (beta diversity) and at the landscape scale (gamma diversity). We analyzed landscape heterogeneity (LH) and its driving factors including environmental variables (LHDF, such as precipitation and altitude), environmental heterogeneity (LHDF) and human activities (LHDF). We used structural equation modeling (SEM) to evaluate the response of species richness to landscape heterogeneity at three scales and determined the relative contribution of driving factors in explaining species diversity at these scales. The results of the study are summarized as follows: 1) Alpha diversity was the dominant component of gamma diversity in the Tabu River basin in Inner Mongolia. 2) There is no significant correlation (P = 0.512) between alpha diversity and LH; with the increase of LH beta and gamma diversities showed hump-shaped relationships. 3) LHDF was the primary factor in maintaining alpha diversity, with heterogeneity of mean annual precipitation (MAP), temperature (MAT) and altitude (ALT) acting as three largest contributors. LHDF primarily contributed to the maintenance of beta diversity. 4) LHDF was the primary contributor to gamma diversity, and human activity exceeded threshold values for positive effects. Based on our findings we suggest liming agricultural use along the river to prevent reductions in species diversity.",
        "keywords": [
            "Agro-pastoral ecotone",
            "Environmental heterogeneity",
            "Land use",
            "Species diversity"
        ],
        "authors": [
            {
                "name": "Qingfu Liu",
                "org": "Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau & Inner Mongolia Key Laboratory of Grassland Ecology, School of Ecology and Environment, Inner Mongolia University, Hohhot 010021, China."
            },
            {
                "name": "Alexander Buyantuev",
                "org": "Department of Geography and Planning, University at Albany, State University of New York, Albany, NY 12222, USA."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing 100875, China; School of Life Sciences and School of Sustainability, Arizona State University, Tempe, AZ 85287, USA."
            },
            {
                "name": "Jianming Niu",
                "org": "Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau & Inner Mongolia Key Laboratory of Grassland Ecology, School of Ecology and Environment, Inner Mongolia University, Hohhot 010021, China."
            },
            {
                "name": "Deyong Yu",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing 100875, China."
            },
            {
                "name": "Qing Zhang",
                "org": "Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau & Inner Mongolia Key Laboratory of Grassland Ecology, School of Ecology and Environment, Inner Mongolia University, Hohhot 010021, China. Electronic address: qzhang82@163.com."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2018
    },
    "iW7ISPDn": {
        "id": "iW7ISPDn",
        "title": "Linking Land-use Change with Ecosystem Processes: A Hierarchical Patch Dynamic Model",
        "abstract": "Urbanization continues to accelerate and profoundly transform the surface of the earth, resulting in devastating effects on the structure and functioning of ecosys- tems throughout the world. In the Phoenix metropolitan region, urbanization has dramatically changed the Sonoran Desert landscape in the past several decades. To understand how urban ecosystems work and to achieve ecological sustainability in urban areas, we must be able to quantify and project land use and land cover change and its ecological consequences. In this paper, we present the theoretical basis and general structure of a hierarchical patch dynamics model (HPDM-PHX) that integrates land use change with ecosystem processes in metropolitan Phoenix. The spatial hierarchical model explicitly considers three spatial scales: the local ecosystem, landscape, and region. Urban systems are studied as dynamic patch mosaics in which a variety of ecological and socioeconomic processes take place, and in which nonlinear interactions between pattern and process at different scales lead to emergent properties. Our major research goals are twofold: to develop and test a hierarchical patch dynamics modeling and scaling approach to regional analysis and assessment, and to develop an understanding of how land use change (mainly urbanization) affects ecosystem production and biogeochemical cycling at the local, landscape, and regional scales in the Phoenix metropolitan area. Al- though HPDM-PHX is developed for a particular urban landscape, the modeling approach should be applicable to other landscapes of different types.",
        "keywords": [
            "hierarchical model",
            "patch dynamics",
            "land use change",
            "spatial scale",
            "emergent properties",
            "biogeochemical cycle",
            "urban ecosystem"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "G. Darrel Jenerette",
                "org": ""
            },
            {
                "name": "John L. David",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2003
    },
    "x5ryu7Q9": {
        "id": "x5ryu7Q9",
        "title": "Borna disease virus P protein affects neural transmission through interactions with gamma-aminobutyric acid receptor-associated protein.",
        "abstract": "Borna disease virus (BDV) is one of the infectious agents that causes diseases of the central nervous system in a wide range of vertebrate species and, perhaps, in humans. The phosphoprotein (P) of BDV, an essential cofactor of virus RNA-dependent RNA polymerase, is required for virus replication. In this study, we identified the gamma-aminobutyric acid receptor-associated protein (GABARAP) with functions in neurobiology as one of the viral P protein-interacting cellular factors by using an approach of phage display-based protein-protein interaction analysis. Direct binding between GABARAP and P protein was confirmed by coimmunoprecipitation, protein pull-down, and mammalian two-hybrid analyses. GABARAP originally was identified as a linker between the gamma-aminobutyric acid receptor (GABAR) and the microtubule to regulate receptor trafficking and plays important roles in the regulation of the inhibitory neural transmitter gamma-aminobutyric acid (GABA). We showed that GABARAP colocalizes with P protein in the cells infected with BDV or transfected with the P gene, which resulted in shifting the localization of GABARAP from the cytosol to the nucleus. We further demonstrated that P protein blocks the trafficking of GABAR, a principal GABA-gated ion channel that plays important roles in neural transmission, to the surface of cells infected with BDV or transfected with the P gene. We proposed that during BDV infection, P protein binds to GABARAP, shifts the distribution of GABARAP from the cytoplasm to the nucleus, and disrupts the trafficking of GABARs to the cell membranes, which may result in the inhibition of GABA-induced currents and in the enhancement of hyperactivity and anxiety.",
        "keywords": [
            "nuclear localization",
            "phage display",
            "protein protein interaction",
            "ion channel",
            "protein binding",
            "rna dependent rna polymerase",
            "central nervous system"
        ],
        "authors": [
            {
                "name": "Guiqing Peng",
                "org": ""
            },
            {
                "name": "Yan Yan",
                "org": ""
            },
            {
                "name": "Chengliang Zhu",
                "org": ""
            },
            {
                "name": "Shiqun Wang",
                "org": ""
            },
            {
                "name": "Xiaohong Yan",
                "org": ""
            },
            {
                "name": "Lili Lu",
                "org": ""
            },
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Jing Hu",
                "org": ""
            },
            {
                "name": "Wei Wei",
                "org": ""
            },
            {
                "name": "Yongxin Mu",
                "org": ""
            },
            {
                "name": "Yanni Chen",
                "org": ""
            },
            {
                "name": "Yong Feng",
                "org": ""
            },
            {
                "name": "Rui Gong",
                "org": ""
            },
            {
                "name": "Kailang Wu",
                "org": ""
            },
            {
                "name": "Fengmin Zhang",
                "org": ""
            },
            {
                "name": "Xiaolian Zhang",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Journal of virology",
        "year": 2008
    },
    "3O63744f": {
        "id": "3O63744f",
        "title": "The impairment of environmental sustainability due to rapid urbanization in the dryland region of northern China",
        "abstract": "Abstract   Rapid urbanization has been taking place in the world’s drylands where water and other essential natural resources are scarce. Assessing the environmental impacts of urban expansion is highly important for the sustainable development of these dryland regions and beyond. Thus, this study aimed to assess the effects of urban expansion on environmental sustainability in the agro-pastoral transitional zone of northern China (APTZNC), a major dryland region of China. We first analyzed the patterns and modes of urban expansion and estimated the dynamics of environmental sustainability by integrating indicators of the environmental elements of water, land, air, and biodiversity from 2000 to 2015. Then, we assessed the impacts of the overall process and the different modes of urban expansion on environmental sustainability based on structural equation models. We found that the APTZNC experienced rapid urban expansion dominated by the edge expansion and leapfrog modes. The urban land area increased from 2169 km 2  to 6128 km 2  at an annual growth rate of 7.17%. This rapid urban expansion had significantly negative influences on environmental sustainability with a path coefficient of −0.98 ( P",
        "keywords": "",
        "authors": [
            {
                "name": "Zhifeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Meihui Ding",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Chunyang He",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jingwei Li",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China"
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2018
    },
    "SBJzkacQ": {
        "id": "SBJzkacQ",
        "title": "Discovery and characterization of the tubercidin biosynthetic pathway from <Emphasis Type=\"Italic\">Streptomyces tubercidicus</Emphasis> NBRC 13090",
        "abstract": "Tubercidin (TBN), an adenosine analog with potent antimycobacteria and antitumor bioactivities, highlights an intriguing structure, in which a 7-deazapurine core is linked to the ribose moiety by an N-glycosidic bond. However, the molecular logic underlying the biosynthesis of this antibiotic has remained poorly understood.",
        "keywords": [
            "Biosynthesis",
            " Tubercidin",
            " 7-deazapurine",
            " Phosphoribosylpyrophosphate",
            " NADPH-dependent reductase",
            " Nudix hydrolase",
            " Synthetic biology"
        ],
        "authors": [
            {
                "name": "Yan Liu",
                "org": "State Key Laboratory of Virology, and College of Life Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Rong Gong",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Xiaoqin Liu",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Peichao Zhang",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, and College of Life Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "You-Sheng Cai",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Zixin Deng",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Margit Winkler",
                "org": "Austrian Centre of Industrial Biotechnology,Graz,Austria"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, and College of Life Sciences,Wuhan University,Wuhan,China"
            },
            {
                "name": "Wenqing Chen",
                "org": "Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and School of Pharmaceutical Sciences,Wuhan University,Wuhan,China"
            }
        ],
        "venue": "Microbial Cell Factories",
        "year": 2018
    },
    "iJAIcd3G": {
        "id": "iJAIcd3G",
        "title": "Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication.",
        "abstract": "Enterovirus 71 (EV71) is the main pathogen causing hand-foot-mouth disease (HFMD) in infants and children, which can also lead to severe neurological diseases and even death. Therefore, understanding the replication mechanism of EV71 is of great significance for the prevention and control of EV71-induced diseases. Beclin1 (BECN1, a mammalian homologue of ATG6 in yeast) is an important core protein for the initiation and the normal process of autophagy in cells. In addition to its involvement in autophagy, Beclin1 has also been reported to play an important role in cancer and innate immune signaling pathways. However, the role of Beclin1 in EV71 replication remains elusive. Here, we primarily found that Beclin1 facilitates EV71 replication in human rhabdomyosarcoma (RD) cells and the autophagy was actually induced, but Beclin1 was not significantly affected at either mRNA level or protein level during early EV71 infection. Further studies discovered that Beclin1 could interacts with EV71 non-structural protein 3D mainly through its evolutionary conserved domain (ECD) and coiled-coiled domain (CCD), thus promoting the replication of EV71 in human rhabdomyosarcoma (RD) cells and human astroglioma (U251) cells. Collectively, we reveal a novel regulatory mechanism associated with Beclin1 to promote EV71 replication, thus providing a potential therapeutic target for the prevention and control of EV71-associated diseases.",
        "keywords": [
            "Beclin1",
            "EV71",
            "EV71 non-structural protein 3D",
            "autophagy",
            "enterovirus 71"
        ],
        "authors": [
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Pin Wan",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Ge Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Siyu Huang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Mengying Qin",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Hua Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Zhen Luo",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            }
        ],
        "venue": "Viruses",
        "year": 2020
    },
    "kZZokiaF": {
        "id": "kZZokiaF",
        "title": "P2.13-30 High-Dose Icotinib in Advanced Non-Small Cell Lung Cancer with EGFR 21 L858R Mutation: The Randomized, Open-Label INCREASE Study",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xia Li",
                "org": ""
            },
            {
                "name": "L. Zhang",
                "org": ""
            },
            {
                "name": "J. Da",
                "org": ""
            },
            {
                "name": "Yan Wang",
                "org": ""
            },
            {
                "name": "A. Zang",
                "org": ""
            },
            {
                "name": "C. Ding",
                "org": ""
            },
            {
                "name": "M. Zhao",
                "org": ""
            },
            {
                "name": "W. Su",
                "org": ""
            },
            {
                "name": "Y. Zhang",
                "org": ""
            },
            {
                "name": "D. Zhong",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "G. An",
                "org": ""
            },
            {
                "name": "C. Zhang",
                "org": ""
            },
            {
                "name": "X. Hu",
                "org": ""
            },
            {
                "name": "G. Cheng",
                "org": ""
            },
            {
                "name": "H. Wang",
                "org": ""
            },
            {
                "name": "Z. Han",
                "org": ""
            },
            {
                "name": "X. He",
                "org": ""
            },
            {
                "name": "J. Liu",
                "org": ""
            },
            {
                "name": "L. Liang",
                "org": ""
            },
            {
                "name": "Shucai Zhang",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2018
    },
    "xcCKb4aV": {
        "id": "xcCKb4aV",
        "title": "Transcriptome comparison between fetal and adult mouse livers: implications for circadian clock mechanisms.",
        "abstract": "Microarray transcriptome analyses of fetal mouse liver did not detect circadian expression rhythms of clock genes or clock-controlled genes, although some rhythmic transcripts that were likely not driven by endogenous cellular clocks were identified. This finding reveals a key distinction between the circadian oscillators in fetal and adult mouse livers. Thus, in this study, the transcriptomes of fetal and adult livers were systematically compared to identify differences in the gene expression profiles between these two developmental stages. Approximately 1000 transcripts were differentially enriched between the fetal and adult livers. These transcripts represent genes with cellular functions characteristic of distinct developmental stages. Clock genes were also differentially expressed between the fetal and adult livers. Developmental differences in liver gene expression might have contributed to the differences in oscillation status and functional states of the cellular circadian clock between fetal and adult livers.",
        "keywords": [
            "biology",
            "circadian clocks",
            "medicine",
            "chemistry",
            "gene expression profiling",
            "transcriptome",
            "fetus",
            "physics",
            "engineering",
            "aging"
        ],
        "authors": [
            {
                "name": "Chengwei Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Shuang Yu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xiaoling Zhong",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xiaodong Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "PloS one",
        "year": 2012
    },
    "ijs8kBJ0": {
        "id": "ijs8kBJ0",
        "title": "Norcantharidin modulates the miR-30a/Metadherin/AKT signaling axis to suppress proliferation and metastasis of stromal tumor cells in giant cell tumor of bone.",
        "abstract": "Giant cell tumor of bone (GCTB) is a benign but locally aggressive tumor, which can cause significant bone destruction at the epiphysis of long bones. Recent studies have demonstrated that norcantharidin (NCTD) can inhibit the proliferation and migration of various human cancer cells, but the role of NCTD in GCTB has not previously been evaluated. The aim of this study was to explore the nature of the anti-cancer effects of NCTD in GCTB and to elucidate the biomolecular mechanisms responsible for these effects. Primary stromal cell cultures, representing the main neoplastic component of GCTB, were used for cell-based experiments. Firstly, the anticancer effects of NCTD on GCTB stromal tumor cells were investigated by CCK-8 assay, flow cytometry and transwell invasion assay. Next, microRNA (miRNA) microarray and quantitative reverse transcription PCR (qRT-PCR) analyses were performed to examine and verify altered expression of miRNAs associated with NCTD treatment. Subsequently, the GCTB stromal cells were transfected with miR-30a inhibitor to confirm its involvement in the observed anti-cancer effects of NCTD. Luciferase reporter assays were carried out to identify the target gene of miR-30a. Moreover, changes in the expression of protein markers of AKT signaling were measured by Western Blot analysis. The results demonstrated that NCTD treatment could inhibit cell proliferation, block the cell cycle process and induce cell apoptosis in GCTB stromal cells. An inhibitory effect of NCTD on GCTB stromal cell invasion through inhibition of epithelial mesenchymal transition (EMT) was also observed. Expression of miR-30a was significantly upregulated by NCTD treatment and miR-30a knockdown significantly reversed the anti-tumor effects of NCTD against GCTB stromal cells. Of note, metadherin (MTDH), a novel oncogene which modulates the AKT pathway, was identified as a direct target of miR-30a in GCTB stromal cells. Further data showed that miR-30a could negatively regulate the expression of MTDH and the AKT pathway in GCTB stromal cells. Importantly, MTDH expression was found to be inversely correlated with miR-30a expression in clinical GCTB specimens. Moreover, NCTD treatment effectively suppressed the AKT signaling pathway as demonstrated by downregulation of phosphorylated-Akt S473 (p-Akt S473), p-Akt (T308), phosphorylated- glycogen synthase kinase (GSK)3 beta (p-GSK3 beta) and c-Myc, whilst miR-30a inhibition re-activated the AKT signaling pathway in GCTB stromal cells. Our findings demonstrate that NCTD can inhibit cell proliferation and metastasis of GCTB stromal cells in vitro, via modulating the miR-30a/MTDH/AKT signaling axis. This suggests that NCTD has potential as a novel therapeutic treatment for GCTB.",
        "keywords": [
            "Giant cell tumor of bone (GCTB)",
            "Norcantharidin",
            "miR-30a/Metadherin/AKT axis",
            "Proliferation",
            "Metastasis"
        ],
        "authors": [
            {
                "name": "Feiyan Chen",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Siqun Wang",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Yibing Wei",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Gangyong Huang",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Jie Chen",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Jingsheng Shi",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            },
            {
                "name": "Jun Xia",
                "org": "Fudan Univ, Huashan Hosp, Dept Orthoped, 12 Middle Urumqi Rd, Shanghai 200040, Peoples R China"
            }
        ],
        "venue": "BIOMEDICINE & PHARMACOTHERAPY",
        "year": 2018
    },
    "QMpDmY8H": {
        "id": "QMpDmY8H",
        "title": "Fermentation conditions optimization of γ-linolenic acid production from potato starch waste water",
        "abstract": "The preparation of γ-linolenic acid(GLA)was studied by fermentation with Cunninghamella echinulata in potato starch waste water.The results showed that the production of GLA reached 750 mg/L when the potato starch waste water was diluted to 6 times with tap water,added 50 g/L glucose and 0.5 g/L(NH4)2SO4,then inoculated with Cunninghamella echinulata to culture for 6 d.Potato starch waste water was an good fermentation material.",
        "keywords": [
            "Cunninghamella echinulata",
            "potato starch waste water",
            "fermentation",
            "γ-linolenic acid"
        ],
        "authors": [
            {
                "name": "WU Jianguo",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Key Laboratory of Molecular Biophysics,Ministry of Education,Wuhan ,China"
            },
            {
                "name": "LI Shuyu",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Key Laboratory of Molecular Biophysics,Ministry of Education,Wuhan ,China"
            },
            {
                "name": "JIN Honglin",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Key Laboratory of Molecular Biophysics,Ministry of Education,Wuhan ,China"
            },
            {
                "name": "ZHANG Xiaoyu",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Key Laboratory of Molecular Biophysics,Ministry of Education,Wuhan ,China"
            }
        ],
        "venue": "China Oils and Fats",
        "year": 2009
    },
    "0EPqzHJZ": {
        "id": "0EPqzHJZ",
        "title": "Arabidopsis putative deacetylase AtSRT2 regulates basal defense by suppressing PAD4, EDS5 and SID2 expression.",
        "abstract": "The silent information regulator protein (Sir2) and its homologs are NAD(+)-dependent deacetylase enzymes that play important roles in a variety of physiological processes. However, the functions of the Sir2 family in plants are poorly understood. Here, we report that Arabidopsis AtSRT2, a homolog of yeast Sir2, negatively regulates plant basal defense against the pathogen Pseudomonas syringae pv. tomato DC3000 (PstDC3000). In response to PstDC3000 infection, the expression of AtSRT2 was down-regulated in a salicylic acid (SA)-independent manner. In addition, knock-out of AtSRT2 (srt2) enhanced resistance against PstDC3000 and increased expression of pathogenesis-related gene 1 (PR1). Conversely, overexpression of AtSRT2 resulted in hypersusceptibility to PstDC3000 and impaired PR1 induction. Consistent with this phenotype, expression of PAD4, EDS5 and SID2, three essential genes in the SA biosynthesis pathway, were increased in the srt2 mutant and decreased in AtSRT2-overexpressing plants. Taken together, these results demonstrate that AtSRT2 is a negative regulator of basal defense, possibly by suppressing SA biosynthesis.",
        "keywords": [
            "basal defense",
            "atsrt2",
            "eds5",
            "pad4",
            "sid2",
            "pstdc3000",
            "bioinformatics",
            "gene expression profiling",
            "biomedical research"
        ],
        "authors": [
            {
                "name": "Chunzheng Wang",
                "org": ""
            },
            {
                "name": "Feng Gao",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Jianli Dai",
                "org": ""
            },
            {
                "name": "Chunhong Wei",
                "org": ""
            },
            {
                "name": "Yi Li",
                "org": ""
            }
        ],
        "venue": "Plant & cell physiology",
        "year": 2010
    },
    "sWSUpujg": {
        "id": "sWSUpujg",
        "title": "Grazing alters ecosystem functioning and C:N:P stoichiometry of grasslands along a regional precipitation gradient",
        "abstract": "The Eurasian steppe has long been subject to grazing by domestic ungulates at high levels, resulting in widespread deterioration of biodiversity and ecosystem services. While abundant evidence demonstrates that heavy grazing alters the ecosystem structure and function of grasslands, research on how grazing specifically affects ecosystem functioning and stoichiometry on broad scales is scarce because of a lack of adequate ungrazed reference sites. We examined the effects of grazing on ecosystem functioning and C : N : P stoichiometry across a precipitation gradient along the 700 km China-Mongolia transect (CMT), covering three community types: meadow steppe, typical steppe and desert steppe. Long-term grazing has dramatically altered the C, N and P pools and stoichiometry of steppe ecosystems along the CMT. Grazing reduced the C, N and P pools in above-ground biomass and litter, while the responses in below-ground biomass and soil C, N and P pools to grazing differed substantially among community types. Grazing increased N content and decreased C : N ratios in all plant compartments, suggesting accelerated N cycling. The altered C : N : P stoichiometry may be explained by changes in the composition of species and functional groups as well as increased foliar N and P contents for the same species in grazed communities. Synthesis and applications. Plant stoichiometric responses to grazing ranged from large in the meadow steppe to small in the typical steppe to generally insignificant in the desert steppe, implying that different underlying mechanisms operated along the regional precipitation gradient. Our findings suggest that reducing the stocking rate and restoring the vastly degraded steppes are essential to sustain native steppe biodiversity, ecosystem functioning and biological capacity for mitigating the impact of climate change in the Inner Mongolia grassland. Plant stoichiometric responses to grazing ranged from large in the meadow steppe to small in the typical steppe to generally insignificant in the desert steppe, implying that different underlying mechanisms operated along the regional precipitation gradient. Our findings suggest that reducing the stocking rate and restoring the vastly degraded steppes are essential to sustain native steppe biodiversity, ecosystem functioning and biological capacity for mitigating the impact of climate change in the Inner Mongolia grassland. © 2012 British Ecological Society.",
        "keywords": [
            "china-mongolia transect",
            "n and p co-limitation",
            "n cycling",
            "plant and soil c",
            "n and p pools",
            "plant functional group composition",
            "primary production",
            "stoichiometry",
            "the eurasian steppe"
        ],
        "authors": [
            {
                "name": "Yongfei Bai",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Christopher M. Clark",
                "org": "Arizona State University(Arizona State University,Arizona State Univ),Tempe,United States"
            },
            {
                "name": "Qingmin Pan",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Lixia Zhang",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Shiping Chen",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Qibing Wang",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xingguo Han",
                "org": "Institute of Botany Chinese Academy of Sciences(Institute of Botany Academia Sinica,Inst. Bot. of Chinese Acad. of Sci.,Institute of Botany,Institute of Botany Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Journal of Applied Ecology",
        "year": 2012
    },
    "ieTT7OKO": {
        "id": "ieTT7OKO",
        "title": "In vitro propagation of Lychnis senno Siebold et Zucc., a rare plant with potential ornamental value",
        "abstract": "Lychnis senno is a rare and valued ornamental plant. Seed propagation is not efficient because of the low germination rate. To grow commercially L. senno in China, a protocol for in vitro germination and propagation of this species was developed. Various germination rates were obtained by treating seeds with GA 3 during 1–6 months storage period. The highest germination rate reached 19.4% when seeds were treated with 250 mg/l GA 3 and stored for 5 months at 4 °C. Axillary shoot proliferation was induced in the nodal segments of the seedlings on medium containing specific concentrations of BA and NAA [Murashige, T., Skoog, F., 1962. A revised medium for rapid growth and bioassays with tobacco tissue culture. Physiol. Plant 15, 473–497] . Maximum number of shoots was developed on a medium supplemented with 5 mg/l BA and 0.5 mg/l NAA, while the higher shoots were observed on a medium supplemented with 0.5 mg/l BA and 0.05 mg/l NAA. Rooting was induced in 91.7% of the regenerated explants on a half-strength MS medium supplemented with 0.5 mg/l NAA. The plantlets grew well and flowered after transfer to the greenhouse. The chromosome numbers of seedlings and propagated plants were also determined to be 2 n = 2 x = 24. Abbreviations GA gibberellic acid BA 6-benzyladenine NAA α-naphthyl acetic acid MS Murashige and Skoog (1962) medium Keywords In vitro germination Multiplication Chromosome observation Lychnis senno 1 Introduction Lychnis senno Siebold et Zucc., belonging to the Caryophyllaceae, is native to the Tianmu Mountain area of China, Lin’an county, Zhejiang province ( Wang, 1993 ). A specific habitat environment is required for the survival and growth of this species. Thus, it is rare and threatened. L . senno is a valued ornamental plant with orange-red flowers. However, little attention was paid to this material by Chinese botanists and horticulturists. The main reason for this is the limitation of suitable environments and low productivity of the species. In nature, the species propagates through seed and vegetative perennial rootstock. According to our preliminary investigations on propagation of L. senno via seed, we found that seed germination took 5–6 months and was sporadic from ex vitro or in vitro culture. Meanwhile, vegetative propagation was not possible as the process of rooting was too slow. Therefore, the development of an in vitro protocol will be of great importance for conservation and sustainable utilization of this species. However, propagation protocols for this species in vitro have not yet been reported. The basic chromosome numbers of L. senno have been reported to be n = 12 and 2 n = 24 ( Wang and Zhang, 1992 ), but no information on the source of materials is available. In Japan, L. senno with 36 chromosomes was reported, considered to be native to China by Japanese scientists, and was presumed to be triploid ( Godo et al., 2000, 2004 ). The purpose of this study of L. senno in vitro propagation methods was to improve the germination rates of seeds and develop a protocol for in vitro propagation and utilization. The chromosome number of the seedlings and regenerants was also observed. 2 Materials and methods 2.1 Plant material, surface sterilization Seeds of L. senno were harvested from a wild population of Tianmu Mountain (1506 m a.s.l.) in late September of 2002. The seeds used in the experiments were used within 6 months. They were air dried and then stored in a refrigerator (4 °C) until the experiments were initiated. 2.2 In vitro germination Seed germination in vitro was performed to provide seedlings and seed-derived explants in sterile conditions. Prior to incubation, seeds were sterilized as follows: (1) seeds were washed in running tap water for 30 min; (2) surface sterilized in 75% ethanol for 1 min; (3) immersed in 1% NaClO solution containing two drops of detergent for 15 min; (4) rinsed with sterile distilled water for about five times under aseptic conditions, followed by being placed on half-strength MS basal medium supplemented with 3% sucrose and 0.8% agar. For the GA 3 treatment, seeds were soaked in 250 mg/l GA 3 solution for 24 h before incubation. The cultures were maintained in the dark at 25 °C until germination, after which the seedlings were illuminated with white fluorescent lights (84 μmol m −2 s −1 ) under 16 h light and 8 h dark photoperiod at 25 °C. The germination rate was tested after 1–6 months storage and GA 3 treatment. Thirty seeds were incubated for each treatment and repeated three times, and the seedlings used in subsequent experiments. 2.3 Shoot formation, multiplication and rooting Shoot tips from in vitro seedlings were excised and cultured on MS medium supplemented with 0.1 mg/l BA and 0.05 mg/l NAA. Shoots formed after 5 weeks culture. Uniform shoots were selected and nodal stem segments with a pair of axillary buds excised from the formed shoots were subcultured on MS medium containing different concentrations of BA and NAA. All concentrations of BA were 0.5, 1, 3 and 5 mg/l, and those of NAA were 0.05, 0.1, 0.5 and 1 mg/l, respectively, 16 combinations in total. The medium was solidified with 0.8% agar and supplemented with 3% sucrose. After 4 weeks of culture, the number and height of newly formed shoots were recorded. Microshoots obtained on MS medium containing 0.5 mg/l BA and 0.05 mg/l NAA were incubated on half-strength MS medium supplemented with different concentrations of NAA at 0.01, 0.1, 0.5, 1.0 and 1.5 mg/l to improve the formation of roots. After 4 weeks culture, the percentage of root formation, the number and length of the formed roots were recorded. 2.4 Ex vitro transfer Plants with better roots were first transplanted into a mixture composed of vermiculite and perlite (1:1) in the culture room for 4 days, and then moved to the greenhouse. 2.5 Chromosome observation Chromosome numbers of the mother plants and regenerants were used for chromosome observation. When the roots reached 1 cm in length, they were treated with 2 mM 8-hydroxyquinoline for 3 h at 22 °C, then fixed in Carnoy's solution for 24 h, and stored in 70% ethanol at 4 °C. Chromosome observation procedure was based on the method of Wu et al. (1997) . 2.6 Statistical analysis Data for each experiment were subjected to two-way analysis of variance (ANOVA). LSDs were used for means comparison. In both cases P < 0.05 was used as the level of significances and differences were denoted in tables by different letters. The treatments were arranged in a completely randomized design with three replicates per treatment and five explants per replicate. 3 Results 3.1 Seed germination The germination rate of seeds was low for storage of 1–6 months in a refrigerator, and was increased with GA 3 treatment as shown in Fig. 1 . The highest germination rate reached 19.4% after 5 months storage. However, the germination rate was still not sufficient for production of the species by seed propagation. Therefore, in vitro propagation of L. senno was performed in the subsequent experiments. 3.2 Shoot formation and multiplication In this experiment, the effects of MS medium with different concentrations of BA and NAA on multiplication of L. senno were investigated. It indicated that there were no significant differences in interactive effects of BA and NAA on shoot multiplication and leaf numbers between these media ( P < 0.05). There were significant differences in interactive effects of BA and NAA on shoot height ( F = 1.951, P = 0.0234) and the effects of BA were significant. The explants cultured on MS medium supplemented with 0.5 mg/l BA produced the highest shoots and the height of shoots were lower with the increase of BA as shown in Table 1 . We made a conclusion, however, that the explants cultured on MS medium supplemented with 5 mg/l BA exhibited the largest multiplication coefficient (2.69) in the present study ( Table 1 ). The multiplication coefficient rose with the increase of BA. Table 1 showed that there were significant differences in the height of shoots, and yet no difference in the number of shoot leaves. Therefore, the higher the shoot, the more nodes were available. About 4000–6500 shoots could be produced from one initial explant in less than 6 months. Less than 1% of shoots in vitro had flowered during the multiplication stage ( Fig. 2 b ). 3.3 Rooting A significant effect of NAA on rooting was observed ( Table 2 ). In the medium containing lower concentration of NAA (0.01 mg/l), rooting was completely inhibited. The highest number and length of roots were observed when shoots were cultured on half-strength MS medium supplemented with 0.5 mg/l NAA. 3.4 Ex vitro performance All plantlets survived in greenhouse, however, they were shorter than native species. The height of micropropagated plants was around 20–35 cm, while 60–90 cm in wild. The anthesis was extended from June to November with the number of flowers between 15 and 20 per plant ( Fig. 2 d), while the wild type flowered in July to August with 1–4 flowers per plant. The flowers of in vitro plants and wild plants were the same in shape and size. 3.5 Chromosome observation Chromosomes of dividing cells in actaphrase were stained and determined to be 2 n = 24 ( Fig. 2 e). A chromosome number of 24 was reported for the first time in L. senno , and were inferred to be the original source of L. senno . 4 Discussion Based on our preliminary study, L. senno seeds have a poor and unpredictable germination rate, and extension of storage period did not improve the germination of this species. These results suggested that L. senno seeds have deep dormancy. It has been reported that there were approaches to break seed dormancy such as hormonal, temperature, etc. ( Seiler, 1998 ). Endogenous GA 3 has been widely studied in relation to the breakage of seed dormancy in various plant species. It has improved the germination of many plant species ( Nicolas et al., 1996; Rehman and Park, 2000 ). In the present study, it was found that the germination rate of GA 3 treated seeds was increased in comparison to the control treatments. In vitro culture technique is an alternative means for germplasm conservation and micropropagation of valuable endangered plants. It has the advantages of preserving healthy plant material in a small space, easy and rapid multiplication for international exchange as well as cost reduction. For large-scale propagation, the number of shoots from one explant is one of the most important factors affecting plant propagation. There was significant difference in the height of shoots in the present study, and larger shoots had more available nodes following subculture, than providing more propagation material. Generally, an addition of BA to the medium could induce the formation of adventitious buds. In the present study, the multiplication coefficient rose with the use of BA and NAA, respectively, but there was no interactive effects of BA and NAA. The flowering of dwarf plants is important for subsequent commercialisation of L. senno . The plant became dwarf when replanted in the greenhouse as compared to the wild type, and the time of flowering was prolonged with more flowers present. Work by Roberts et al. (1995) showed that the height of Dicentra spectabilis could be controlled with daminozide, and the flower opening enhanced by STS (the anionic silver thiosulfate complex) treatment. However, in the present study, we achieved similar results with tissue culture and as such, L. senno may be acceptable to be commercially propagated through this means as a potted and landscape plant. Acknowledgements The first author would like to thank Prof. Masahiro Mii of the Laboratory of Plant Cell Technology, Faculty of Horticulture, Chiba University, for comments and information on this species. The authors also wish to thank Mr. Li for seed collection and Mr. Yang for statistical assistance. References Godo et al., 2000 T. Godo T. Oku M. Mii M. Nakata In vitro culture for preservation of triploid senno, a valuable and rare ornamental plant Bull. Bot. Gard. Toyama 5 2000 35 43 Godo et al., 2004 T. Godo T. Oku M. Mii M. Nakata Triploid property of Senno ( Lychnis senno Siebold et Zucc., Caryophyllaceae), a traditional ornamental plant conserved in Japan Breed. Sci. 54 2004 105 109 Murashige and Skoog, 1962 T. Murashige F. Skoog A revised medium for rapid growth and bioassays with tobacco tissue culture Physiol. Plant 15 1962 473 497 Nicolas et al., 1996 C. Nicolas G. Nicolas D. Rodriguez Antagonistic effects on abscisic acid and gibberellic acid on the breaking of dormancy of Fagus sylvatica seeds Physiol. Plant 96 1996 244 250 Rehman and Park, 2000 S. Rehman I.H. Park Effect of scarification, GA and chilling on the germination of golden rain-tree ( Koelreuteria paniculata Laxm.) seeds Sci. Hort. 85 2000 319 324 Roberts et al., 1995 C.M. Roberts M. Serek A.S. Andersen Supplemental irradiance and STS improve the display life of Dicentra species forced as flowering potted plants Sci. Hort. 62 1995 121 128 Seiler, 1998 G.J. Seiler Seed maturity, storage time and temperature, and media treatment effects on germination of two wild sunflowers Agron. J. 90 1998 221 226 Wang and Zhang, 1992 H.P. Wang S.Z. Zhang Chromosome studies on five species of caryophyllaceae plants J. Wuhan Bot. Res. 10 2 1992 179 181 Wang, 1993 J.X. Wang Flora of Zhejiang 1993 Zhejiang Science and Technology Publishing House 2 pp. 234–235 Wu et al., 1997 J.G. Wu Z. Li Y. Liu H.L. Liu T.D. Fu Cytogenetics and morphology of the pentaploid hybrid between Brassica napus and Orychophragmus violaceus and its progeny Plant Breed. 116 1997 251 257",
        "keywords": [
            "chromosome observation",
            "in vitro germination",
            "lychnis senno",
            "multiplication",
            "tissue culture",
            "ornamental plant"
        ],
        "authors": [
            {
                "name": "Liping Chen",
                "org": ""
            },
            {
                "name": "Yanju Wang",
                "org": "Department of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Chunxia Xu",
                "org": "Department of Horticulture, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            },
            {
                "name": "Mingshui Zhao",
                "org": "Zhejiang Tianmu Mountain National Nature Reserve Management Bureau, Lin’an 311311, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China"
            }
        ],
        "venue": "Scientia Horticulturae",
        "year": 2006
    },
    "6x9jPYC7": {
        "id": "6x9jPYC7",
        "title": "Association of Vpu with hepatitis C virus NS3/4A stimulates transcription of type 1 human immunodeficiency virus.",
        "abstract": "Type 1 human immunodeficiency virus (HIV-1) and hepatitis C virus (HCV) are deadly bloodborne-transmitting pathogens. Due to sharing the routes of transmission, co-infection of HIV-1 and HCV is common with a high rate. Co-infection of HCV affects morbidity and mortality of patients with AIDS and impairs their tolerance to antiretroviral therapy. In this study, the roles of HCV proteins in the regulation of HIV-1 replication and the molecular mechanism involved in such regulation were investigated. We demonstrated that HCV NS3 protein stimulated HIV-1 LTR transcription and that HIV-1 Vpu protein was required for the activation of HIV-1 transcription regulated by HCV NS3/4A complex. Further study revealed that Vpu mediated ubiquitination-associated degradation of NS4A, detached NS3/4A complex and release NS3 for nuclear translocation. Since both degradation of NS4A and activation of HIV-1 LTR were closely correlated and mediated by Vpu, we proposed that Vpu impairs the stability of NS4A and releases NS3 from NS3/4A complex for the stimulation of HIV-1 transcription. This study enriched our understanding on HIV-1/HCV co-infection and provided new insights in molecular mechanism involved in the co-infection of the two viruses.",
        "keywords": [
            "vpu",
            "hiv-1",
            "co-infection",
            "hcv",
            "ns3/4a"
        ],
        "authors": [
            {
                "name": "Lei Kang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Zhen Luo",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Youxing Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wenjing Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wei Sun",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Wei Li",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Fang Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xueshan Xia",
                "org": "Kunming University of Science and Technology(Kunming University of Science and Technology),Kunming,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Virus research",
        "year": 2012
    },
    "5R8BXYLE": {
        "id": "5R8BXYLE",
        "title": "Analysis of Variations in the Amylose Content of Grains Located at Different Positions in the Rice Panicle and the Effect of Milling",
        "abstract": "",
        "keywords": [
            "amylose content",
            "quality",
            "rice grain"
        ],
        "authors": [
            {
                "name": "Xiao-Ming Zhang",
                "org": ""
            },
            {
                "name": "Chun-Hai Shi",
                "org": ""
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Horiuchi Hisamitus",
                "org": ""
            },
            {
                "name": "Tomita Katsura",
                "org": ""
            },
            {
                "name": "Shui-Ying Feng",
                "org": ""
            },
            {
                "name": "Gen-Liang Bao",
                "org": ""
            },
            {
                "name": "Sheng-Hai Ye",
                "org": ""
            }
        ],
        "venue": "Starch-starke",
        "year": 2003
    },
    "Fg098B7l": {
        "id": "Fg098B7l",
        "title": "The effects of pneumatic tourniquet on patellofemoral kinematics",
        "abstract": "Objective To describe the different kinematic characters of patellofemoral joint with pneumatic tourniquet at extensed and flexed knees.Methods 20 healthy knees of inpatients with consents were enrolled in the research.Caton Index and trochlear angle were recorded at 30° flexion of knees under lumbar aneasthesia with tourniquet free.We set the pneumatic tourniquet at extension knee and extremely flexion knee as contrast groups,and the Laurin angle and merchant congruent angle were recorded at 30°,45°,60°,90° and 120° of knee position.These angles were compared to describe different patellofemoral kinematics.Results At 30° flexion,Caton Index averaged(1.02±0.19) and trochlear angle was(138.9±7.4)°.The merchant congruent angle became larger during knee flexing,especially when the knee flexed from 30° to 45°.The Laurin angle presented no significant change in the range of knee flexion.The Merchant congruent angle and Laurin angle of patellofemoral joint showed no significant difference with pneumatic tourniquet secured at neither extensed nor flexed positions.Conclusions For normal knees,the main kinematic effect of pneumatic tourniquet on the patellofemoral joint with different knee flexion is observed as increase of Merchant congruent angle at the initial 45° flexion of knee,while Laurin angle keeps no significant change in the range of motion.The kinematic characters of patellofemoral joint show no significant difference with pneumatic tourniquet secured at meither extensed nor flexed positions.",
        "keywords": [
            "Patellofemoral joint",
            "Biomechanics",
            "Tourniquets"
        ],
        "authors": [
            {
                "name": "HUANG Gang-yong",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "WEI Yi-bing",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "CHEN Fei-yan",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "CHEN Jie",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "ZHANG Yu",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "WANG Si-qun",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            },
            {
                "name": "XIA Jun",
                "org": ".Depart of Orthopedics,Huashan Hospital,Fudan Unversity,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Joint Surgery(Electronic Edition)",
        "year": 2010
    },
    "rv2sSDC4": {
        "id": "rv2sSDC4",
        "title": "Effect of Pea-Fer Gene on Quality Characters of Transgenic Rice",
        "abstract": "A transgenic rice line of Fer34-XS11 containing Pea-Fer was backcrossed from donor parent(exogenous ferritin transgenic pure lines Fer34)and recurrent parent(Oryza sativa ssp.japanica)(Xiushui 11)successively with GUS detection method.The pure line and the former recipient parent(Xiushui 11)form a pair of isogenic lines,which were used to study the effect of Pea-Fer gene on main quality characters of the rice.It was found that the appearance of transgenic lines,chalkiness degree,transparency,gelatinization temperature,gel consistence and amylose content between the two kinds of rice are similar in the aspects of appearance,cooking and eating quality.Moreover,in the aspect of nutritional quality,the iron content of Fer34-XS11 was significantly increased,but there was no significant differences in other mineral elements,protein and amino acid.Furthermore,the RVA profile,texture,the structure and pattern of the amyloplasts with scanning electron microscopic are the same as those of contrast.These results indicated that Pea-Fer gene in transgenic rice only improved the iron content,but could not cause the quality characters change compared with its original parent.",
        "keywords": [
            "rice",
            "texture",
            "transgenosis",
            "Pea-Fer",
            "RVA profile",
            "scanning electron microscopy",
            "nutritive quality",
            "cooking and eating quality"
        ],
        "authors": [
            {
                "name": "Zhao Fei",
                "org": "College of Agriculture and Biotechnology,Zhejiang University1,Hangzhou "
            },
            {
                "name": "Ren Sanjuan",
                "org": "College of Agriculture and Biotechnology,Zhejiang University1,Hangzhou "
            },
            {
                "name": "Guo Zejian",
                "org": "Department of Plant Pathology,China Agricultural University2,Beijing "
            },
            {
                "name": "Wu Jianguo",
                "org": "College of Agriculture and Biotechnology,Zhejiang University1,Hangzhou "
            },
            {
                "name": "Bao Jinsong",
                "org": "College of Agriculture and Biotechnology,Zhejiang University1,Hangzhou "
            },
            {
                "name": "Shen Shengquan",
                "org": "College of Agriculture and Biotechnology,Zhejiang University1,Hangzhou "
            }
        ],
        "venue": "Journal of the Chinese Cereals and Oils Association",
        "year": 2011
    },
    "XdblIsNx": {
        "id": "XdblIsNx",
        "title": "Compilation and practice for &quot;Genetics&quot; multimedia textbook]",
        "abstract": "Textbook is an important tool for generating knowledge and is closely related to the teaching effect. Now the multimedia teaching method has become the common norm in teaching process of higher education. This paper describes the compilation of different forms of \"Genetics\" multimedia textbook, the selection of contents and knowledge, the ar-rangement of knowledge module and systematic configuration. The characteristics of compiling process of multimedia textbook are also discussed.",
        "keywords": [
            "genetics",
            "multimedia textbook",
            "teaching effect"
        ],
        "authors": [
            {
                "name": "Chun-Hai Shi",
                "org": "Agronomy Department, Zhejiang University, Hangzhou, China. chhshi@zju.edu.cn"
            },
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Qiu-Lan Ma",
                "org": ""
            }
        ],
        "venue": "Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji",
        "year": 2009
    },
    "BDle5ykK": {
        "id": "BDle5ykK",
        "title": "Etiological and epidemic analysis of hand-foot-mouth disease in Wuhan and adjacent cities in 2011",
        "abstract": "Objective To find out more about the characteristics of aetiology and epidemiology of hand-foot-mouth di-sease(HFMD) and to provide laboratory data for epidemic control and patient care.Methods Throat swab samples were collected from 1844 cases of HFMD,and enterovirus(EV)71 and coxsackie virus A(CA)16 were detected by real-time PCR.Results Among 1844 HFMD samples,20.2% were infected with EV71,24.9% with CA16 and 2.1% cases with both.There were two high-incidence peaks of HFMD during 2011.One peak was from May to July,2011 when EV71 was the chief pathogen.The other was from Sept to Dec,2011,with CA16 as the chief pathogen.The peak incidence of HFMD appeared in the age groups of 1-3 years and most of them were from home.Boys outnumbered girls.Fever and central ner-vous system complications were significantly more frequent in patients with EV71 infection than those with CA16 infection.Conclusion HMFD in Wuhan and adjacent cities was mainly caused by EV71 and CA16 in 2011.Both were the main pathogens of the two seasonal peaks.A better knowledge of the composition of pathogens and characteristics of epidemiology plays an important role in the surveillance and control of HFMD.",
        "keywords": [
            "enterovirus 71(EV71)",
            "hand-foot-mouth disease",
            "etiology",
            "coxsackie virus A16(CA16)",
            "epidemiology"
        ],
        "authors": [
            {
                "name": "YIN Ji-dong",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "WU Shi-min",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "XIANG Jie",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "ZHOU Hong",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "WU Zhi-qiang",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "LI Hong-ze",
                "org": "Department of Clinic Laboratory,Wuhan Medical Treatment Center,Wuhan ,China"
            },
            {
                "name": "LIU Wei-yong",
                "org": "College of Life Sciences,Wuhan University,Wuhan ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Life Sciences,Wuhan University,Wuhan ,China"
            }
        ],
        "venue": "Military Medical Sciences",
        "year": 2013
    },
    "fGVRRBnE": {
        "id": "fGVRRBnE",
        "title": "Inhibition of hepatitis B virus replication by recombinant small interfering RNAs.",
        "abstract": "RNA interference (RNAi) is a biological phenomenon in which introduction of a small, double-stranded interfering RNAs (siRNAs) into a cell causes a specific degradation of homologous single-stranded RNA. siRNA can be delivered into the cell by different approaches including synthetic RNA, in vitro transcribed RNA and RNA transcribed from polymerase III-based recombinant vectors. As hepatitis B (HB) represents a worldwide health problem, we attempted to develop a fast and easy approach to generation and screening of specific siRNA-targeted HB virus (HBV) genes. Using PCR amplification, specific siRNA expression cassettes (SECs) were developed and used to generate effective siRNAs against HB virus (HBV) replication and gene expression in mammalian cells. After screening, we identified two SECs that expressed siRNAs which efficiently decreased the level of HBV pre-c/c gene expression in transfected Bel-7402 cells by 81.9% and 87.3%, respectively. In addition, the level of HBV DNA was decreased by 83.5% and 85.2% in HepG2 2.2.15 cells, respectively. This study provides (i) a new effective application of RNA interference to study viral gene function and viral replication and (ii) a new tool for the prevention and treatment of human HBV infection.",
        "keywords": [
            "hbv dna replication",
            "sirnas",
            "hbv replication",
            "rna interference",
            "hepatitis b virus"
        ],
        "authors": [
            {
                "name": "K Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Y Gong",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "X Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Y Zhang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Y Mu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "F Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "D Song",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Y Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "J Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Acta virologica",
        "year": 2005
    },
    "WOuPBpR9": {
        "id": "WOuPBpR9",
        "title": "Cullin1 binds and promotes NLRP3 ubiquitination to repress systematic inflammasome activation.",
        "abstract": "Activation of the NACHT, leucine-rich repeat, and pyrin domains-containing protein 3 (collectively known as NLRP3) inflammasome plays a key role in host immune response, which is the first line of defense against cellular stresses and pathogen infections. However, excessive inflammasome activation damages host cells, and therefore it must be precisely controlled. Here, we discover that Cullin1 (CUL1), a key component of the Skp1-Cullin1-F-box E3 ligase, plays a critical role in controlling the NLRP3 inflammasome. CUL1 represses inflammasome assembly in cultured cells, suppresses NLRP3 function in human monocytic cell line macrophages, and attenuates inflammatory responses in mouse model. Detailed studies demonstrate that CUL1 interacts with NLRP3 and promotes NLRP3 ubiquitination, but not protein degradation, to repress the NLRP3 inflammasome activation. Moreover, upon inflammatory stimuli, including ATP and nigericin treatments, CUL1 disassociates from NLRP3 to release the repression of the NLRP3 inflammasome. Thus, this study reveals a distinct and unique mechanism underlying the control of systematic activation of the NLRP3 inflammasome.-Wan, P., Zhang, Q., Liu, W., Jia, Y., Ai, S., Wang, T., Wang, W., Pan, P., Yang, G., Xiang, Q., Huang, S., Yang, Q., Zhang, W., Liu, F., Tan, Q., Zhang, W., Wu, K., Liu, Y., Wu, J. Cullin1 binds and promotes NLRP3 ubiquitination to repress systematic inflammasome activation.",
        "keywords": [
            "Skp1-Cullin1-F-box complex",
            "innate immune response",
            "interleukin 1 beta, IL-1β",
            "proinflammatory cytokines",
            "ubiquitin-proteasome system"
        ],
        "authors": [
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yaling Jia",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Sha Ai",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Tianci Wang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China; and."
            },
            {
                "name": "Pan Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Ge Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Xiang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Siyu Huang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qingyu Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qiuping Tan",
                "org": "Guangdong LongFan Biological Science and Technology Company, Foshan, China."
            },
            {
                "name": "Wen Zhang",
                "org": "Guangdong LongFan Biological Science and Technology Company, Foshan, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China; and."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou, China; and."
            }
        ],
        "venue": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology",
        "year": 2019
    },
    "4tZZA4HJ": {
        "id": "4tZZA4HJ",
        "title": "Major vault protein: a virus-induced host factor against viral replication through the induction of type-I interferon.",
        "abstract": "Major vault protein (MVP) is the major constituent of vaults and is involved in multidrug resistance, nucleocytoplasmic transport, and cell signaling. However, little is known about the role of MVP during viral infections. In this study, high levels of MVP were found in peripheral blood mononuclear cells, sera, and liver tissue from patients infected with hepatitis C virus (HCV) relative to healthy individuals. HCV infections resulted in elevated levels of MVP messenger RNA (mRNA) and protein expression in the hepatocyte cell lines Huh7.5.1 and Huh7. Further studies demonstrated that the nuclear factor kappa B (NF-κB) and Sp1 pathways are involved in the induction of MVP expression by HCV. Interestingly, MVP expression suppressed HCV replication and protein synthesis by way of induction of type-I interferon mRNA expression and protein secretion. Upon investigating the mechanisms behind this event, we found that MVP enhanced the expression of interferon regulatory factor 7 (IRF7), but not IRF3. Translocation of activated IRF7 and NF-κB from the cytosol to the nucleus was involved in this process. Furthermore, vesicular stomatitis virus, influenza A virus, and enterovirus 71 also induced MVP production, and MVP in turn hampered viral replication and production.MVP is a novel virus-induced host factor and its expression up-regulates type-I interferon production, leading to cellular antiviral responses.",
        "keywords": [],
        "authors": [
            {
                "name": "Shi Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Qian Hao",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Nanfang Peng",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Xin Yue",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yu Wang",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yanni Chen",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Ying Zhu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "Hepatology (Baltimore, Md.)",
        "year": 2012
    },
    "gJJYRbdO": {
        "id": "gJJYRbdO",
        "title": "Soil organic carbon mineralization and its affecting factors under four typical vegetations in mid Qilian Mountains",
        "abstract": "To understand the effects of varying soil temperature and moisture content on soil organic carbon(SOC)mineralization under mountain forest,alpine meadow,desert steppe,and arid steppe in mid Qilian Mountains,an anaerobic incubation test with orthogonal design was conducted in an artificial climatic chamber.The results showed that the cumulative amount of mineralized SOC was higher at 35 ℃ or 25 ℃ than at 5 ℃,and was the lowest at soil moisture content of 10%.The soil under mountain forest had the highest cumulative amount of mineralized SOC,followed by that under alpine meadow,and under desert steppe or arid steppe.The SOC mineralization rate was significantly higher at 35 ℃ or 25 ℃ than at 5 ℃,and at 35 ℃ than at 15 ℃,and lower under desert steppe and arid steppe than under mountain forest and alpine meadow.The cumulative amount of mineralized SOC as well as the SOC mineralization rate decreased with incubation time,and the effects of soil temperature and ecosystem type on them were significant(P<0.05).It was considered that soil temperature was the dominant factor affecting the SOC mineralization under the mountain forest,alpine meadow,desert steppe,and arid steppe in mid Qilian Mountains,and the dynamics of the SOC mineralization could be better fitted by first order equation.",
        "keywords": [
            "Alpine meadow",
            "Arid steppe",
            "Desert steppe",
            "Mountain forest",
            "Qilian Mountains",
            "Soil organic carbon mineralization"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "AI Li",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China;Science and Technology University of Beijing,Beijing ,China"
            },
            {
                "name": "CHANG Wei",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China;Beijing Forestry University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Ecology",
        "year": 2007
    },
    "M5grqYlc": {
        "id": "M5grqYlc",
        "title": "Regulation of Rice Tillering by RNA-directed DNA Methylation at Miniature Inverted-repeat Transposable Elements.",
        "abstract": "Tillering is a major determinant of rice plant architecture and grain yield. Here we report that depletion of rice OsNRPD1a and OsNRPD1b, two orthologues of the largest subunit of RNA polymerase IV, leads to a high-tillering phenotype, in addition to dwarfism and smaller panicles. OsNRPD1a and OsNRPD1b are required for the production of 24-nt siRNAs that direct DNA methylation at transposable elements (TEs) including Miniature Inverted-repeat TEs (MITEs). Interestingly, many genes are regulated either positively or negatively by TE methylation. Among them, OsMIR156d and OsMIR156j, which promote rice tillering, are repressed by CHH methylation at two MITEs in the promoters. By contrast, D14, which suppresses rice tillering, is activated by CHH methylation at a MITE in its downstream. Our findings reveal control of rice tillering by RdDM at MITEs and provide potential targets for agronomic trait enhancement by epigenome editing.",
        "keywords": [
            "D14",
            "MITEs",
            "OsMIR156",
            "RdDM",
            "Tiller",
            "siRNA"
        ],
        "authors": [
            {
                "name": "Le Xu",
                "org": "Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China."
            },
            {
                "name": "Kun Yuan",
                "org": "Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China."
            },
            {
                "name": "Meng Yuan",
                "org": "Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China."
            },
            {
                "name": "Xiangbing Meng",
                "org": "Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China."
            },
            {
                "name": "Min Chen",
                "org": "Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Vector-borne Virus Research Center, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou 350002, China."
            },
            {
                "name": "Jiayang Li",
                "org": "Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: jyli@genetics.ac.cn."
            },
            {
                "name": "Yijun Qi",
                "org": "Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China. Electronic address: jyli@genetics.ac.cn."
            }
        ],
        "venue": "Molecular plant",
        "year": 2020
    },
    "nSQP3Auk": {
        "id": "nSQP3Auk",
        "title": "Glycosylation of classical swine fever virus Erns is essential for binding double-stranded RNA and preventing interferon-beta induction",
        "abstract": "Host cells sense double-stranded RNA (dsRNA) produced during viral replication and initiate type I interferon (IFN-alpha/beta) production, leading to subsequent antiviral responses. Many viruses, including classical swine fever virus (CSFV), have developed strategies for counteracting the IFN-alpha/beta response. In this study, we explored the role of the CSFV E(rns) glycoprotein in the inhibition of IFN-beta production induced by dsRNA [poly(IC)]. Our results demonstrated that CSFV E(rns) could bind to exogenous dsRNA and inhibit dsRNA-induced IFN-beta production but failed to inhibit TRIF-triggered IFN-beta production. Our data suggest that the inhibition of IFN-beta induction occurred at the initial step of the TLR3 signaling pathway. We also showed that deglycosylation of E(rns) rendered it unable to bind to dsRNA, and thus unable to inhibit dsRNA-induced IFN-beta production. Taken together, these results indicated that N-glycan of CSFV E(rns) is essential for E(rns) blocking of IFN-beta induction.",
        "keywords": [
            "type i interferon",
            "glycoprotein e rns",
            "dsrna",
            "classical swine fever virus",
            "rna",
            "viral replication",
            "glycoproteins"
        ],
        "authors": [
            {
                "name": "Xuelian Luo",
                "org": "State key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Ruangang Pan",
                "org": ""
            },
            {
                "name": "Chao Wan",
                "org": "State key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Xinfeng Liu",
                "org": "State key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Zishu Pan",
                "org": ""
            }
        ],
        "venue": "Virus Research",
        "year": 2009
    },
    "7k1zFgA6": {
        "id": "7k1zFgA6",
        "title": "Relationship between Geographic Distribution of Endemic Birds and Climatic Factors in China",
        "abstract": "The relationship between endemic birds of China and climatic factors was analyzed.The results show that there are 8 wide distribution and 63 stenotopic distribution endemic bird species in China.There are 33 continuous distribution and 38 discontinuous distribution endemic bird species,and 67 resident and 4 migrant bird species in China.The number of endemic bird species is low in most parts of China,although it is higher in the central and northwestern regions of Sichuan Province,the southern region of Gansu Province,and the southeastern region of Qinghai Province.The number of species is higher in the 93°E-121°E or 26°N-39°N regions of China.The distribution of endemic birds in China is restricted by climatic factors.The numbers of species is low in locations where the air temperature is too high or too low,precipitation is too high or too low,relative humidity is too low,or solar exposure time is too long or too short.According to climatic factors,the suitable types of endemic birds in China can be divided into those suitable for low temperatures and low relative humidity,higher temperatures and higher relative humidity,highest temperatures and highest relative humidity,and medium temperatures and medium relative humidity.Most endemic bird species in China are suitable for low temperatures and low relative humidity,and medium temperatures and medium humidity.The correlation coefficients between the abundance of endemic birds in China and climatic factors are low,and the changing of abundance shows a parabolic type under different climatic factors.The abundance is higher under conditions of air temperature 1-18 ℃ or annual precipitation 500-1300 mm.",
        "keywords": [
            "bird",
            "geographical distribution",
            "climatic factors",
            "endemic species"
        ],
        "authors": [
            {
                "name": "WU Mei-xiang",
                "org": "School of Geographical Sciences,Southwest University,Chongqing ,China;Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "KUANG Ming-sheng",
                "org": "School of Geographical Sciences,Southwest University,Chongqing ,China"
            },
            {
                "name": "HENG Tao",
                "org": "School of Geographical Sciences,Southwest University,Chongqing ,China;Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2011
    },
    "ST7xAwnu": {
        "id": "ST7xAwnu",
        "title": "Hepatitis B virus enhances interleukin-27 expression both in vivo and in vitro.",
        "abstract": "The immune system plays important roles in determining the outcomes of hepatitis B virus (HBV) infection. Interleukin-27 (IL-27) is a recently identified pro-inflammatory cytokine produced by macrophages, dendritic cells, and epithelial cells. To determine the correlation between HBV infection and IL-27 expression, we investigated the serum IL-27 levels in patients with HBV infection and in healthy individuals. Results showed that IL-27 was significantly elevated in patients as compared to healthy individuals (P<0.001). IL-27 was also detected at higher levels in patients with liver cirrhosis or hepatocellular carcinoma than those with acute hepatitis B or chronic hepatitis B (P<0.05). We also found that IL-27 expression was influenced by HBV e antigen. In addition, our in vitro studies demonstrated that IL-27 promoter activity, mRNA and protein expression were all stimulated in cells transfected with infectious HBV clone.",
        "keywords": [
            "hbv e antigen",
            "acute hepatitis b",
            "liver cirrhosis",
            "cytokines",
            "interleukin-27",
            "hepatitis b virus",
            "chronic hepatitis b",
            "hepatocellular carcinoma",
            "in vitro",
            "immune system",
            "protein expression",
            "epithelial cell",
            "interleukins",
            "immune response"
        ],
        "authors": [
            {
                "name": "Chengliang Zhu",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Rui Zhang",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Li Liu",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Sahibzada T Rasool",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yongxin Mu",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Wei Sun",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Qian Hao",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fang Liu",
                "org": "The State Key Laboratory of Virology and College of Life Sciences, Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Clinical immunology (Orlando, Fla.)",
        "year": 2009
    },
    "73uMwfHl": {
        "id": "73uMwfHl",
        "title": "Exploration and Experiment of the Constructing the Teaching Material of Integration of Working and Learning for Higher Vocational Mechanical Engineering",
        "abstract": "The paper induced and distilled systematically the problems existing in the construction of teaching material in the mechanical engineering in the current higher vocational education.The construction of the teaching material must be strengthened primarily on the basis of constructing the connotation by strengthening the construction of teachers team,course and organization and management,and made suggestions on the content and forms in compiling the teaching material through working and learning integration,and explored and experimented the teaching material Common Processing of the Mechanical Parts as an example.",
        "keywords": [
            "Higher vocational",
            "construction of teaching material",
            "integration of working and learning"
        ],
        "authors": [
            {
                "name": "JIN Jie",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2012
    },
    "9rdNIa3k": {
        "id": "9rdNIa3k",
        "title": "Evaluating empirical scaling relations of pattern metrics with simulated landscapes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Weijun Shen",
                "org": ""
            },
            {
                "name": "G. Darrel Jenerette",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Robert H. Gardner",
                "org": ""
            }
        ],
        "venue": "Ecography",
        "year": 2004
    },
    "kdyUku01": {
        "id": "kdyUku01",
        "title": "Induction of Interferon-λ Contributes to TLR3 and RIG-I Activation-Mediated Inhibition of Herpes Simplex Virus Type 2 Replication in Human Cervical Epithelial Cells.",
        "abstract": "Is it possible to immunologically activate human cervical epithelial cells to produce antiviral factors that inhibit herpes simplex virus type 2 (HSV-2) replication?Our results indicate that human cervical epithelial cells possess a functional TLR3/RIG-I signaling system, the activation of which can mount an Interferon-λ (IFN-λ)-mediated anti-HSV-2 response.There is limited information about the role of cervical epithelial cells in genital innate immunity against HSV-2 infection.We examined the expression of toll-like receptors (TLRs) and retinoic acid-inducible I (RIG-I) in End1/E6E7 cells by real-time PCR. The IFN-λ induced by TLR3 and RIG-I activation of End1/E6E7 cells was also examined by real-time PCR and ELISA. HSV-2 infection of End1/E6E7 cells was evaluated by the real-time PCR detection of HSV-2 gD expression. The antibody to IL-10Rβ was used to determine whether IFN-λ contributes to TLR3/RIG-I mediated HSV-2 inhibition. Expression of interferon regulatory factor 3 (IRF3), IRF7, IFN-stimulated gene 56 (ISG56), 2'-5'-oligoadenylate synthetase I (OAS-1) and myxovirus resistance A (MxA) were determined by the real-time PCR and Western-blot. End1/E6E7 cells were transfected with shRNA to knockdown the IRF3, IRF7 or RIG-I expression. Student's t-test and post Newman-Keul's test were used to analyze stabilized differences in the immunological parameters above between TLR3/RIG-I-activated cells and control cells.Human cervical epithelial cells expressed functional TLR3 and RIG-I, which could be activated by poly I:C and 5'ppp double-strand RNAs (5'ppp dsRNA), resulting in the induction of endogenous interferon lambda (IFN-λ). The induced IFN-λ contributed to TLR3/RIG-I-mediated inhibition of HSV-2 replication in human cervical epithelial cells, as an antibody to IL-10Rβ, an IFN-λ receptor subunit, could compromise TLR3/RIG-I-mediated inhibition of HSV-2. Further studies showed that TLR3/RIG-I signaling in the cervical epithelial cells by dsRNA induced the expression of the IFN-stimulated genes (ISGs), ISG56, 2'-5'-oligoadenylate synthetase I (OAS-1) and myxovirus resistance A (MxA), the key antiviral elements in the IFN signaling pathway. In addition, we observed that the topical treatment of genital mucosa with poly I:C could protect mice from genital HSV-2 infection.Future prospective studies with primary cells and suitable animal models are needed in order to confirm these outcomes.The findings provide direct and compelling evidence that there is intracellular expression and regulation of IFN-λ in human cervical epithelial cells, which may have a key role in the innate genital protection against viral infections.Large scale data: Not applicable.This work was supported by the National Natural Science Foundation of China (81301428 to L.Z. and 81271334 to W-Z. H.), the Fundamental Research Funds for the Central Universities (2042015kf0188 to L.Z.) the China Postdoctoral Science Foundation (2013M531745 to L.Z.), the Development Program of China (\"973\", 2012CB518900 to W-Z. H.) from the Ministry of Science and Technology of the People's Republic of China, grants (DA12815 and DA022177 to W-Z. H.) from the National Institute on Drug Abuse (NIDA) and the open project of Hubei Key Laboratory of Wudang Local Chinese Medicine Research (WDCM005 to M.S.). The authors declare no competing financial interests.",
        "keywords": [
            "Herpes simplex virus type 2",
            "Toll-like receptor 3",
            "human cervical epithelial cells",
            "interferon-stimulated genes",
            "interferon-λ",
            "retinoic acid-inducible gene I"
        ],
        "authors": [
            {
                "name": "Li Zhou",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Jie-Liang Li",
                "org": "Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA."
            },
            {
                "name": "Yu Zhou",
                "org": "Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA."
            },
            {
                "name": "Jin-Biao Liu",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Ke Zhuang",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Jian-Feng Gao",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Shi Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Ming Sang",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Jian-Guo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430071, China."
            },
            {
                "name": "Wen-Zhe Ho",
                "org": "Animal Biosafety Level III Laboratory at the Center for Animal Experiment, Wuhan University, Wuhan 430071, China Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA wenzheho@temple.edu."
            }
        ],
        "venue": "Molecular human reproduction",
        "year": 2015
    },
    "1fThnOeB": {
        "id": "1fThnOeB",
        "title": "QTL Analysis of Maternal and Endosperm Genomes for Histidine and Arginine in Rice (Oryza sativa L.) Across Environments",
        "abstract": "This study was conducted to identify QTL governing histidine (His) and arginine (Arg) contents of rice ( Oryza sativa L.). A newly developed method for QTL mapping was used, which included endosperm and maternal main effects and the interactions between QTL and environment. Two backcross populations, which were composed of a set of 241 RILs derived from the cross between Zhenshan 97 (BC 1 F 1 ) and Minghui 63 (BC 2 F 1 ), were used in 2 environments. Ten QTLs associated with His content were mapped on chromosomes 1, 2, 3, 6, 7, 10, 11, and 12 and 8 QTLs associated with Arg content were on chromosomes 2, 3, 5, 6, 7, 10, 11, and 12. All of them had significant additive effects from triploid endosperm and diploid maternal plant. Furthermore, 4 out of the 18 QTLs, 2 for His content and 2 for Arg content, showed significant dominant main effects from triploid endosperm. Obvious interactions between QTL and environment were detected for 7 QTLs, including 5 associated with His content and 2 associated with Arg contents. The results indicated that the QTLs for His and Arg contents of rice were distributed over several chromosomes and the interaction effects between QTL and environment were also important for the performance of these nutrient quality traits.",
        "keywords": [
            "interaction effects between qtl and environment",
            "quantitative trait locus (qtl)",
            "maternal plant",
            "rice",
            "qtl mapping",
            "quantitative trait locus",
            "interaction effect"
        ],
        "authors": [
            {
                "name": "Xi ZHENG",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou 310020, China"
            },
            {
                "name": "Jian-Guo WU",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou 310020, China"
            },
            {
                "name": "Xiang-Yang LOU",
                "org": "Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22911, USA"
            },
            {
                "name": "Hai-Ming XU",
                "org": "Department of Agronomy, Zhejiang University, Hangzhou 310020, China"
            },
            {
                "name": "Chun-Hai SHI",
                "org": ""
            }
        ],
        "venue": "Acta Agronomica Sinica",
        "year": 2008
    },
    "ZFeYUuaX": {
        "id": "ZFeYUuaX",
        "title": "The virus-induced signaling adaptor molecule enhances DNA-raised immune protection against H5N1 influenza virus infection in mice.",
        "abstract": "As an adaptor molecule in the retinoic acid-inducible gene-I (RIG-I) signaling pathway, the virus-induced signaling adaptor (VISA) molecule activates NF-κB and IRF3 and thereby leads to the production of type I interferons (IFNs). To explore the potential of VISA as a genetic adjuvant for DNA vaccines, a eukaryotic expression plasmid, pVISA, was generated by cloning the VISA gene into the pVAX1vector. For comparison, the pTRIF plasmid was similarly constructed, encoding the known genetic adjuvant TRIF (TIR-domain-containing adapter-inducing interferon-β), an adapter in the Toll-like receptor (TLR) signaling pathway. Mice were immunized with the chimeric DNA vaccine pHA/NP(147-155), which encodes the HA (hemagglutinin) fused with NP (nucleoprotein) CTL epitope (NP(147-155)) of H5N1 influenza virus, either alone or in combination with pVISA or pTRIF. Antigen-specific immune responses were examined in immunized mice. Our results demonstrate that co-immunization of the pHA/NP(147-155) plasmid with the VISA adjuvant augmented DNA-raised cellular immune responses and provided protection against H5N1 influenza virus challenge in mice. In addition, our data suggest that VISA acts as a stronger adjuvant for DNA immunization than TRIF. We conclude that co-inoculation with a vector expressing the adaptor molecule VISA enhanced the protective immunity against H5N1 infection induced by pHA/NP(147-155) and that VISA could be developed as a novel genetic adjuvant for DNA vaccines.",
        "keywords": [
            "visa",
            "h5n1 influenza virus",
            "trif",
            "genetic adjuvant",
            "dna vaccines",
            "dna vaccine",
            "signaling pathway",
            "genetics",
            "immune response"
        ],
        "authors": [
            {
                "name": "Mengcheng Luo",
                "org": ""
            },
            {
                "name": "Xiao Qu",
                "org": ""
            },
            {
                "name": "Ruangang Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei Province, Wuhan 430072, PR China"
            },
            {
                "name": "Dandan Zhu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei Province, Wuhan 430072, PR China"
            },
            {
                "name": "Yuan Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei Province, Wuhan 430072, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei Province, Wuhan 430072, PR China"
            },
            {
                "name": "Zishu Pan",
                "org": ""
            }
        ],
        "venue": "Vaccine",
        "year": 2011
    },
    "7vBNVGdO": {
        "id": "7vBNVGdO",
        "title": "Quantifying spatiotemporal patterns of urbanization: The case of the two fastest growing metropolitan regions in the United States",
        "abstract": "Urbanization is the most drastic form of land use change affecting biodiversity and ecosystem functioning and services far beyond the limits of cities. To understand the process of urbanization itself as well as its ecological consequences, it is important to quantify the spatiotemporal patterns of urbanization. Based on historical land use data, we characterize the temporal patterns of Phoenix and Las Vegas – the two fastest growing metropolitan regions in the United States – using landscape pattern metrics at multiple spatial resolutions. Our results showed that the two urban landscapes exhibited strikingly similar temporal patterns of urbanization. During the past several decades, urbanization in the two desert cities resulted in an increasingly faster increase in the patch density, edge density, and structural complexity at both levels of urban land use and the entire landscape. That is, as urbanization continued to unfold, both landscapes became increasingly more diverse in land use, more fragmented in structure, and more complex in shape. The high degree of similarity between the two metropolitan regions may be attributable to their resemblance in the natural environment, the form of population growth, and the stage of urban development. While our results corroborated some theoretical predictions in the literature, they also showed spatiotemporal signatures of urbanization that were different from other cities. Resolving these differences can certainly further our understanding of urban dynamics. Finally, this study suggests that a small set of landscape metrics is able to capture the main spatiotemporal signatures of urbanization, and that the general patterns of urbanization do not seem to be significantly affected by changing grain sizes of land use maps when the spatial extent is fixed. This landscape pattern analysis approach is not only effective for quantifying urbanization patterns, but also for evaluating spatial urban models and investigating ecological effects of urbanization.",
        "keywords": [
            "las vegas",
            "spatiotemporal patterns of urbanization",
            "spatial pattern analysis",
            "scale",
            "landscape metrics",
            "phoenix",
            "land use change",
            "population growth",
            "natural environment",
            "structural complexity",
            "urban development",
            "land use",
            "grain size",
            "spatial resolution"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "G. Darrel Jenerette",
                "org": "Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA"
            },
            {
                "name": "Alexander Buyantuyev",
                "org": "Sino-US Center for Conservation, Energy, and Sustainability Science (SUCCESS), Inner Mongolia University, Hohhot, China"
            },
            {
                "name": "Charles L. Redman",
                "org": "School of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            }
        ],
        "venue": "Ecological Complexity",
        "year": 2011
    },
    "trbRZAOL": {
        "id": "trbRZAOL",
        "title": "Study on Extraction Technology of Triterpenic Acid from Ganoderma duropora Lloyd",
        "abstract": "Objective To study the optimal extraction process for triterpenic acid from Ganoderma duropora Lloyd.Methods The orthogonal experiment and ethanol reflux method were used to optimize the extraction process.Results The main influencing factor of triterpenic acid from Ganoderma duropora Lloyd extracted by 95% ethanol reflux was temperature,the next was extraction time,and the last was ratio of material to solvent.The optimal conditions for the extraction were obtained as follow as the ratio of material to solvent 1:25 at 60℃ for 2 hours,the extraction times was 2,then the average yield of triterpenic acid was 6.53%(RSD=2.57%).Conclusion The method is simple,and the yield of triterpenic acid is high under the conditions.The process can be used for the extraction of triterpenic acid from Ganoderma duropora Lloyd.",
        "keywords": [
            "extraction technology",
            "Ganoderma duropora Lloyd",
            "triterpenic acid"
        ],
        "authors": [
            {
                "name": "WU Jianguo",
                "org": "Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian ,China"
            },
            {
                "name": "WANG Minhui",
                "org": "College of Pharmacy,FUTCM,Fuzhou,Fujian ,China"
            },
            {
                "name": "WU Yanbin",
                "org": "Fujian Academy of Integrative Medicine,FUTCM,Fuzhou,Fujian ,China"
            }
        ],
        "venue": "Journal of Fujian University of Traditional Chinese Medicine",
        "year": 2011
    },
    "JYhvMGcw": {
        "id": "JYhvMGcw",
        "title": "Value of lower extremity weight-bearing full-length radiographs prepared before total knee arthroplasty",
        "abstract": "Objective To evaluate the effectiveness of preoperative weight-bearing full-length (WBFL) radiographs of lower extremities in total knee arthroplasty (TKA). Methods We retrospectively reviewed 138 cases (138 knees) of TKA in Huashan hospital, among which there were 58 males and 80 females with average age 71.6 years, 66 knees with femur combined with tibia radiographs or with regional knee radiographs (segmental group) and 72 knees with WBFL radiographs preoperatively (WBFL group). There was no significant difference in age, sex, body mass index, primary diseases of the knees and the American Knee Society (AKS) scores before surgery among two groups (P>0.05). The malalignment test and operation plan were done in all cases based on the radiographs available and all patella in this study were unresurfaced. All cases were followed-up for 6 months at least, and their postoperative alignment of lower extremities with TKA and AKS scores were compared between these two groups. Results The postoperative AKS and complication rate of WBFL group was similar to that of segmental group (P>0.05). The WBFL group got better postoperative mechanical alignment restored with no outliner when residual deformity of 3° varus or valgus as the marginal value while 4 knees were malaligned postoperatively beyond 3° in segmental group (P<0.05). Conclusions The WBFL radiographs do work to better restore mechanical axis of the malaligned lower extremities in TKA and it should be recommended routinely preoperatively.",
        "keywords": [
            "Total knee arthroplasty",
            "X-ray radiography",
            "Alignment of lower extremity"
        ],
        "authors": [
            {
                "name": "HUANG Gang-yong",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "XIA Jun",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "ZHENG Yu-ze",
                "org": " Department of Radiology, Huashan Hospital, Fudan University2, Shanghai , China"
            },
            {
                "name": "WANG Si-qun",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "WEI Yi-bing",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "WU Jian-guo",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "CHEN Fei-yan",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "CHEN Jie",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "SHI Jing-sheng",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            },
            {
                "name": "WEI Li-cheng",
                "org": ". Department of Orthopaedics, Huashan Hospital, Fudan University1, Shanghai "
            }
        ],
        "venue": "International Journal of Orthopaedics",
        "year": 2012
    },
    "xENev3Rx": {
        "id": "xENev3Rx",
        "title": "How much of the world’s land has been urbanized, really? A hierarchical framework for avoiding confusion",
        "abstract": "Urbanization has transformed the world’s landscapes, resulting in a series of ecological and environmental problems. To assess urbanization impacts and improve sustainability, one of the first questions that we must address is: how much of the world’s land has been urbanized? Unfortunately, the estimates of the global urban land reported in the literature vary widely from less than 1–3 % primarily because different definitions of urban land were used. To evade confusion, here we propose a hierarchical framework for representing and communicating the spatial extent of the world’s urbanized land at the global, regional, and more local levels. The hierarchical framework consists of three spatially nested definitions: “urban area” that is delineated by administrative boundaries, “built-up area” that is dominated by artificial surfaces, and “impervious surface area” that is devoid of life. These are really three different measures of urbanization. In 2010, the global urban land was close to 3 %, the global built-up area was about 0.65 %, and the global impervious surface area was merely 0.45 %, of the word’s total land area (excluding Antarctica and Greenland). We argue that this hierarchy of urban land measures, in particular the ratios between them, can also facilitate better understanding the biophysical and socioeconomic processes and impacts of urbanization.",
        "keywords": [
            "Urbanization",
            " Global urban land",
            " Urban area",
            " Built-up area",
            " Impervious surface",
            " Hierarchy of definitions"
        ],
        "authors": [
            {
                "name": "zhifeng liu",
                "org": "beijing normal university"
            },
            {
                "name": "chunyang he",
                "org": "beijing normal university"
            },
            {
                "name": "yuyu zhou",
                "org": "pacific northwest national laboratory"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2014
    },
    "Qf3vLIlQ": {
        "id": "Qf3vLIlQ",
        "title": "Identification and characterization of <i>dwarf 62</i>, a loss-of-function mutation in <i>DLT</i>/<i>OsGRAS</i>-<i>32</i> affecting gibberellin metabolism in rice",
        "abstract": "A dwarf mutant, dwarf 62 (d62), was isolated from rice cultivar 93-11 by mutagenesis with γ-rays. Under normal growth conditions, the mutant had multiple\n abnormal phenotypes, such as dwarfism, wide and dark-green leaf blades, reduced tiller numbers, late and asynchronous heading,\n short roots, partial male sterility, etc. Genetic analysis indicated that the abnormal phenotypes were controlled by the recessive\n mutation of a single nuclear gene. Using molecular markers, the D62 gene was fine mapped in 131-kb region at the short arm of chromosome 6. Positional cloning of D62 gene revealed that it was the same locus as DLT/OsGRAS-32, which encodes a member of the GRAS family. In previous studies, the DLT/OsGRAS-32 is confirmed to play positive roles in brassinosteroid (BR) signaling. Sequence analysis showed that the d62 carried a 2-bp deletion in ORF region of D62 gene which led to a loss-of-function mutation. The function of D62 gene was confirmed by complementation experiment. RT-PCR analysis and promoter activity analysis showed that the D62 gene expressed in all tested tissues including roots, stems, leaves and panicles of rice plant. The d62 mutant exhibited decreased activity of α-amylase in endosperm and reduced content of endogenous GA1. The expression levels of gibberellin (GA) biosynthetic genes including OsCPS1, OsKS1, OsKO1, OsKAO, OsGA20ox2/SD1 and OsGA2ox3 were significantly increased in d62 mutant. Briefly, these results demonstrated that the D62 (DLT/OsGRAS-32) not only participated in the regulation of BR signaling, but also influenced GA metabolism in rice.",
        "keywords": [
            "dlt/osgras-32 � dwarf 62 d62 � gibberellin ga � positional cloning � rice oryza sativa l."
        ],
        "authors": [
            {
                "name": "Wenqiang Li",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Shili Weng",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Yujiang Zhang",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Dapeng Zhang",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310029 China"
            }
        ],
        "venue": "",
        "year": 2010
    },
    "BF34W4Zx": {
        "id": "BF34W4Zx",
        "title": "miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression.",
        "abstract": "Differentiation of committed precursor cells into the osteoblast lineage is tightly regulated by several factors, including Runx2 and BMP2. We previously reported that C terminus of Hsc70-interacting protein/STIP1 homology and U-Box containing protein 1 (CHIP/STUB1) negatively regulated osteoblast differentiation through promoting Runx2 protein degradation. However, how CHIP is regulated during osteoblast differentiation remains unknown. In this study, we found that miR-764-5p is up-expressed during the osteoblast differentiation in calvarial and osteoblast progenitor cells, coupled with down-expression of CHIP protein. We observed that forced expression or inhibition of miR-764-5p decreased or increased the CHIP protein level through affecting its translation by targeting the 3'-UTR region. Perturbation of miR-764-5p resulted in altered differentiation fate of osteoblast progenitor cells and the role of miR-764-5p was reversed by overexpression of CHIP, whereas depletion of CHIP impaired the effect of miR-764-5p. Our data showed that miR-764-5p positively regulates osteoblast differentiation from osteoblast progenitor cells by repressing the translation of CHIP protein.",
        "keywords": [
            "chip",
            "mir-764-5p",
            "mirna",
            "runx2",
            "osteoblast differentiation"
        ],
        "authors": [
            {
                "name": "Junwei Guo",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Fangli Ren",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Yinyin Wang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Shan Li",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Zhengrong Gao",
                "org": "Capital Medical University China(Capital University of Medical Sciences,Capital Medical University),Beijing,China"
            },
            {
                "name": "Xiaoyan Wang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Hongxiu Ning",
                "org": "University of California, San Francisco(University of California),San Francisco,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Yi Li",
                "org": "Peking University(Peking University),Beijing,China"
            },
            {
                "name": "Zhao Wang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            },
            {
                "name": "Shek Man Chim",
                "org": "University of Western Australia(University of Western Australia),Perth,Australia"
            },
            {
                "name": "Jiake Xu",
                "org": "University of Western Australia(University of Western Australia),Perth,Australia"
            },
            {
                "name": "Zhijie Chang",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research",
        "year": 2012
    },
    "dsQvqIMb": {
        "id": "dsQvqIMb",
        "title": "The Inspiration on the Disease Management in China from the Experience in Health Management Abroad",
        "abstract": "The health management service in foreign countries is developing rapidly,such as the UK's NHS system,the U.S. health insurance plans,etc.But the health management service in China is still in its infancy.Especially the diseases management models are still at the stage of exploring.The experience in health management abroad can provide inspirations to China' s disease management service.",
        "keywords": [
            "community health",
            "health records",
            "disease management",
            "Health management"
        ],
        "authors": [
            {
                "name": "Zhang Yue",
                "org": ",et al,School of Health Policy &Management.Nanjing Medical University.Nanjing ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": ",et al,School of Health Policy &Management.Nanjing Medical University.Nanjing ,China"
            },
            {
                "name": "Lu Jianhua",
                "org": ",et al,School of Health Policy &Management.Nanjing Medical University.Nanjing ,China"
            }
        ],
        "venue": "Jiangsu Healthcare Administration",
        "year": 2011
    },
    "s388Tw2U": {
        "id": "s388Tw2U",
        "title": "Association of functional polymorphism of ApoB promoter with hepatitis C virus infection.",
        "abstract": "Hepatitis C virus (HCV) binds to apolipoprotein B (ApoB) and low-density lipoprotein (LDL) before entering into hepatocytes. ApoB promoter polymorphisms influence the levels of ApoB and LDL in blood. We investigated the correlations between ApoB promoter polymorphism and HCV infection.ApoB promoter polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 243 HCV-infected patients and 346 healthy individuals. Serum lipids concentrations were measured in all subjects.ApoB polymorphisms on -516 position in patients were statistically different from healthy individuals (p<0.0001). CC genotype was higher in patients (58.7%) than in healthy individuals (43.1%) (p<0.0001). TT genotype was lower in patients (6.2%) than in healthy group (16.1%) (p<0.0001). C allele frequency was higher (76.3%) in patients than in healthy individuals (63.4%) (p<0.0001). T allele was lower in patients (23.7%) than in controls (36.6%) (p<0.0001). CC genotype was higher in HCV RNA positive patients (63.5%) than in negative ones (45.9%) (p<0.0001). TT genotype was significantly higher in HCV RNA negative patients (19.2%) than in positive individuals (2.6%) (p<0.0001).CC genotype of ApoB promoter at -516 position may increase susceptibility of HCV infection and TT genotype may be associated with viral clearance.",
        "keywords": [
            "viral hepatitis",
            "hepatitis c virus",
            "polymorphism",
            "apolipoprotein b",
            "viral infection and clearance",
            "genotypes",
            "alleles",
            "genes",
            "risk factors",
            "promoters"
        ],
        "authors": [
            {
                "name": "Chengliang Zhu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Rui Zhang",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Dandan Liu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Weiyong Liu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Guiqing Peng",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ke Wang",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Qian Hao",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yilin Xu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fang Liu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": "The State Key Laboratory of Virology, College of Life Sciences and Chinese-French Liver Disease Research Institute (Zhongnan Hospital), Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Clinica chimica acta; international journal of clinical chemistry",
        "year": 2009
    },
    "TpVbQSB9": {
        "id": "TpVbQSB9",
        "title": "Optimization of solid fermentation condition of kudzu root residue by Schizophyllum commune",
        "abstract": "The solid fermentation condition of kudzu root residue by Schizophyllum commune DS1 in rock-flask was optimized,and the optimal condition was validated by scale-up in space bag.After the optimization,the optimal condition were that mixed kudzu root residue was the fermentation substrate,and the solid-to-liquid ratio was 1:1.5,and adding bran was 10% in mass,and seed age was 3 days,and the inoculation volume was 6mL/100g,and the temperature of fermentation was 28℃.Under the condition,the content of isoflavone was increased over 70% and the content of dietary fiber was increased over 5%.At last,the optimal condition was validated in space bag,the result could be realized the one in rock-flask.",
        "keywords": [
            "Schizophyllum commune",
            "kudzu root residue",
            "fermentation",
            "dietary fiber",
            "isoflavone"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "GE Juan",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "YU Wei",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "DENG Xiao-hua",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            },
            {
                "name": "ZHANG Xiao-yu",
                "org": "School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan ,China"
            }
        ],
        "venue": "Science and Technology of Food Industry",
        "year": 2010
    },
    "IlGQJQlQ": {
        "id": "IlGQJQlQ",
        "title": "Transcriptome profiling confirmed correlations between symptoms and transcriptional changes in RDV infected rice and revealed nucleolus as a possible target of RDV manipulation.",
        "abstract": "Rice dwarf virus (RDV) is the causal agent of rice dwarf disease, which limits rice production in many areas of south East Asia. Transcriptional changes of rice in response to RDV infection have been characterized by Shimizu et al. and Satoh et al.. Both studies found induction of defense related genes and correlations between transcriptional changes and symptom development in RDV-infected rice. However, the same rice cultivar, namely Nipponbare belonging to the Japonic subspecies of rice was used in both studies.Gene expression changes of the indica subspecies of rice, namely Oryza sativa L. ssp. indica cv Yixiang2292 that show moderate resistance to RDV, in response to RDV infection were characterized using an Affymetrix Rice Genome Array. Differentially expressed genes (DEGs) were classified according to their Gene Ontology (GO) annotation. The effects of transient expression of Pns11 in Nicotiana benthaminana on the expression of nucleolar genes were studied using real-time PCR (RT-PCR).856 genes involved in defense or other physiological processes were identified to be DEGs, most of which showed up-regulation. Ribosome- and nucleolus related genes were significantly enriched in the DEGs. Representative genes related to nucleolar function exhibited altered expression in N. benthaminana plants transiently expressing Pns11 of RDV.Induction of defense related genes is common for rice infected with RDV. There is a co-relation between symptom severity and transcriptional alteration in RDV infected rice. Besides ribosome, RDV may also target nucleolus to manipulate the translation machinery of rice. Given the tight links between nucleolus and ribosome, it is intriguing to speculate that RDV may enhance expression of ribosomal genes by targeting nucleolus through Pns11.",
        "keywords": [
            "virology",
            "cell nucleolus",
            "real time polymerase chain reaction",
            "microarray analysis",
            "gene expression profiling"
        ],
        "authors": [
            {
                "name": "Liang Yang",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,China"
            },
            {
                "name": "Zhenguo Du",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,China"
            },
            {
                "name": "Feng Gao",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences,Peking University,Beijing,China"
            },
            {
                "name": "Kangcheng Wu",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,China"
            },
            {
                "name": "Lianhui Xie",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,China"
            },
            {
                "name": "Yi Li",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences,Peking University,Beijing,China"
            },
            {
                "name": "Zujian Wu",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China. wuzujian@126.com."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,China"
            }
        ],
        "venue": "Virology journal",
        "year": 2014
    },
    "eEODcpo7": {
        "id": "eEODcpo7",
        "title": "Disentangling the Complex Effects of Socioeconomic, Climatic, and Urban Form Factors on Air Pollution: A Case Study of China",
        "abstract": "China’s tremendous economic growth during the past three decades has resulted in worsening air quality in most of its cities. However, the spatiotemporal patterns and underlying drivers of air pollution in China remain poorly understood. To address this issue, we used stepwise regression to identify major socioeconomic, climatic, and urban form factors influencing air pollution in 69 major cities across China. Our results showed that social factors such as population size and density were positively correlated with emissions of PM2.5, PM10, NOx, and SO2. Economic factors such as Gross Domestic Product (GDP) and GDP of secondary industry were positively correlated with industry and transportation emissions but negatively correlated with residential emissions of air pollutants. Urban form attributes such as measures of urban fragmentation and contiguity were important in explaining patterns of emissions from residential, power generation, and transportation sectors. As for climatic factors, higher precipitation, higher wind speed, and higher temperatures were all negatively correlated with air pollution levels. We also found that the effects of socioeconomic, climatic, and urban from factors on air pollution levels varied considerably among seasons and between the annual and seasonal scales. Our findings have useful implications for urban planning and management for controlling air pollution in China and beyond.",
        "keywords": "",
        "authors": [
            {
                "name": "Yupeng Liu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Yupeng Liu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            },
            {
                "name": "Deyong Yu",
                "org": "Beijing Normal University"
            }
        ],
        "venue": "Sustainability",
        "year": 2018
    },
    "3FF6JY7S": {
        "id": "3FF6JY7S",
        "title": "Research Progress of natural compounds used in the treat ment of Diabetes Mellitus",
        "abstract": "Diabetes mellitus(DM),refered to as Xiao Ke Bing in traditional Chnese medicine(TCM),is becoming a serious threat to mankind health.Although some synthetic drugs have been employed to lessen blood sugar presenting eutherapeutic effects,there are still unfortunate toxicity and side effects.TCM,performing a good clinical practice in DM and its complications,has been used in China for 2000 years in accordance with TCM theory.With the development of natural medicine chemistry and modern medicine,numerous potentially active natural compounds have been isolated,which mechanism was revealed in a variety of pathways.From this point of view,this paper reviews active natural compounds used as treatment of DM reported presently,including flavonoids,alkaloids,terpenoids and anthraquinones.The present review aim to arouse wide concern on the natural compounds used in the treatment of DM and its complications.",
        "keywords": [
            "Diabetes mellitus",
            "Traditional Chinese medicine",
            "Natural compounds"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Academy of integrative medicine,Fujian University of traditional Chinese medicine Fuzhou ,China"
            },
            {
                "name": "WU Yan-bin",
                "org": "Academy of integrative medicine,Fujian University of traditional Chinese medicine Fuzhou ,China"
            },
            {
                "name": "XU Hui-feng",
                "org": "Academy of integrative medicine,Fujian University of traditional Chinese medicine Fuzhou ,China"
            },
            {
                "name": "CAI Qiao-yan",
                "org": "Academy of integrative medicine,Fujian University of traditional Chinese medicine Fuzhou ,China"
            },
            {
                "name": "WU Jin-zhong",
                "org": "Academy of integrative medicine,Fujian University of traditional Chinese medicine Fuzhou ,China"
            }
        ],
        "venue": "Strait Pharmaceutical Journal",
        "year": 2011
    },
    "unabOKnr": {
        "id": "unabOKnr",
        "title": "RNase P Ribozymes Inhibit the Replication of Human Cytomegalovirus by Targeting Essential Viral Capsid Proteins",
        "abstract": "",
        "keywords": [
            "rnase p",
            "ribozyme",
            "gene targeting"
        ],
        "authors": [
            {
                "name": "zhu yang",
                "org": ""
            },
            {
                "name": "michael reeves",
                "org": ""
            },
            {
                "name": "jun ye",
                "org": ""
            },
            {
                "name": "phong trang",
                "org": ""
            },
            {
                "name": "li zhu",
                "org": ""
            },
            {
                "name": "jingxue sheng",
                "org": ""
            },
            {
                "name": "yu wang",
                "org": ""
            },
            {
                "name": "ke zen",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "fenyong liu",
                "org": ""
            }
        ],
        "venue": "Viruses",
        "year": 2015
    },
    "B9DOa9HE": {
        "id": "B9DOa9HE",
        "title": "Rich lizards: How affluence and land cover influence the diversity and abundance of desert reptiles persisting in an urban landscape",
        "abstract": "Fourteen native lizard species inhabit the desert surrounding Phoenix, AZ, USA, but only two occur within heavily developed areas. This pattern is best explained by a combination of socioeconomic status, landcover, and location. Lizard diversity is highest in affluent areas and lizard abundance is greatest near large patches of open desert. The percentage of building cover had a strong negative impact on both diversity and abundance. Despite Phoenix's intense urban heat island effect, which strongly constrains the potential activity and microhabitat use of lizards in summer, thermal patterns have not yet impacted their distribution and relative abundance at larger scales. As Phoenix emerges from an economic recession, efforts to restrict urban sprawl and encourage higher density development could lower water and energy use while benefiting lizards in undisturbed habitats. However, this would likely exacerbate the urban heat island effect, and pose a threat to native species within the urban landscape. (C) 2014 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Urban",
            "Ecology",
            "Lizards",
            "Landscape",
            "Land-cover",
            "Urban heat island",
            "Mitigation",
            "Reptiles"
        ],
        "authors": [
            {
                "name": "jeffrey w ackley",
                "org": "Arizona State Univ, Sch Life Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "jianguo wu",
                "org": "Arizona State Univ, Sch Life Sci & Sch Sustainabil, Tempe, AZ 85287 USA"
            },
            {
                "name": "michael j angilletta",
                "org": "Arizona State Univ, Sch Life Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "soe w myint",
                "org": "Arizona State Univ, Sch Geog Sci & Urban Planning, Tempe, AZ 85287 USA"
            },
            {
                "name": "brian l sullivan",
                "org": "Arizona State Univ, Sch Math & Nat Sci, Phoenix, AZ 85069 USA"
            }
        ],
        "venue": "BIOLOGICAL CONSERVATION",
        "year": 2015
    },
    "skxVfuQz": {
        "id": "skxVfuQz",
        "title": "The Assessment of the Soil Quality and Health of Desert Soil",
        "abstract": "The ecosystem health and soil sources sustainability are directly impacted by the soil quality and health.Assessment soil quality and health rationally is important for management the soil resources and ecosystem.Desert soil belongs to typical soil class and it is the basement of developing economy for desert region.In this article,the concept,standard,indicator and assess methods of estimating desert soil quality and health were discussed and the quality and health of soil in China were assessed simply.",
        "keywords": [
            "desert ecosystem",
            "soil quality",
            "soil health"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": ""
            }
        ],
        "venue": "Chinese Horticulture Abstracts",
        "year": 2009
    },
    "a6GloDaL": {
        "id": "a6GloDaL",
        "title": "Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation to Induce Vascular Leakage in Mice.",
        "abstract": "Dengue virus (DENV) infection causes serious clinical symptoms, including Dengue hemorrhagic fever (DHF) and Dengue shock syndrome (DSS). Vascular permeability change is the main feature of the diseases, and the abnormal expression of pro-inflammation cytokines is the important cause of vascular permeability change. However, the mechanism underlying vascular permeability induced by DENV is not fully elucidated. Here we reveal a distinct mechanism by which DENV infection promotes the NLRP3 inflammasome activation and interleukin-1 beta (IL-1β) release to induce endothelial permeability and vascular leakage in mice. DENV M protein interacts with NLRP3 to facilitate the NLRP3 inflammasome assemble and activation, which lead to the induction of pro-inflammation cytokine IL-1β activation and release. Notably, M can induce vascular leakage in mice tissues through activating NLRP3 inflammasome and IL-1β. More importantly, inflammatory cell infiltration and tissue injuries are induced by M in WT mice tissues, but they are not affected by M in NLRP3 knock-out (NLRP3) mice tissues, and Evans blue intensities in WT mice tissues are significantly higher as compared with NLRP3 mice tissues, demonstrating an essential role of NLRP3 in M-induced vascular leakages in mice. Therefore, we propose that upon DENV infection, M interacts with NLRP3 to facilitate the inflammasome activation and IL-1β secretion, which lead to induction of endothelial permeability and vascular leakage in mice tissues. The important role of the DENV-M-NLRP3-IL-1β axis in the induction of vascular leakage provides new insights into the mechanisms underlying DENV pathogenesis and DENV-associated DHF and DSS development. Dengue virus (DENV) is a mosquito-borne pathogen and its infection is prevalent in over 100 tropical and sub-tropical countries or regions with approximately 2.5 billion people at risk. DENV infection induces a spectrum of clinical symptoms ranging from classical dengue fever (DF) to severe dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Therefore, it is important to understand the mechanisms underlying DENV pathogenesis. In this study, the authors reveal that the DENV membrane protein (M) interacts with the host NLRP3 protein to promote the NLRP3 inflammasome activation, which leads to the activation and release of pro-inflammation cytokine, interleukin-1 beta (IL-1β). More importantly, the authors demonstrate that M protein can induce vascular permeability and vascular leakage and NLRP3 is required for M-induced vascular leakage in mice tissues. Collectively, this study reveals a distinct mechanism underlying DENV pathogeneses and provides new insights into the development of therapeutic agent for DENV-associated diseases.",
        "keywords": "",
        "authors": [
            {
                "name": "Pan Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Zizhao Lao",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou 510405, China."
            },
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Miaomiao Shen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Feng Xiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wen Zhang",
                "org": "Guangdong LongFan Biological Science and Technology, Foshan 528315, China."
            },
            {
                "name": "Quiping Tan",
                "org": "Guangdong LongFan Biological Science and Technology, Foshan 528315, China."
            },
            {
                "name": "Xiaohong Liu",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou 510405, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Geng Li",
                "org": "Center for Animal Experiment, Guangzhou University of Chinese Medicine, Guangzhou 510405, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            }
        ],
        "venue": "Journal of virology",
        "year": 2019
    },
    "41OPmMq5": {
        "id": "41OPmMq5",
        "title": "Expression of Id3 in A549/DDP cells and its significance",
        "abstract": "Objective: The Id proteins,also referred to as inhibitors of differentiation,express abnormally in a variety of human tumors and participate in the proliferation,differentiation and apoptosis of tumorous cells.We designed our study to investigate the expression of Id3 in Cisplatin resistant human lung adenocarcinoma A549/DDP cells in vitro and its significance.Methods: We constructed the recombinant eukaryotic expression vector Id3/pEGFP containing human Id3 cDNA and EGFP fusion genes,and transfected them into A549/DDP cells by the liposome-mediated method.After the transfection,we observed the EGFP expression by fluorescent microscopy,detected the alteration of the Id3 expression by semi-quantitative RT-PCR,and determined cell proliferation and inhibition by MTT assay.Results: The human eukaryotic expression vector Id3/pEGFP was successfully constructed and transfected into A549/DDP cells.RT-PCR showed that Id3 mRNA was effectively expressed in the Id3/pEGFP-transfected A549/DDP cells,and the growth of these cells was significantly inhibited.Conclusion: The transfected Id3/EGFP fusion genes can be effectively expressed in A549/DDP cells,and the exogenous Id3 gene can suppress the proliferation of these cells.",
        "keywords": [
            "Lung adenocarcinoma",
            "Transfection",
            "Expression",
            "A549/DDP",
            "Inhibitor of differentiation 3"
        ],
        "authors": [
            {
                "name": "WANG Shu-xia",
                "org": "College of Preclinical Medicine and Medical Technology,Jiangsu University,Zhenjiang ,Jiangsu,China;PLA Research Institute of Clinical Laboratory Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "LI Xiao-jun",
                "org": "PLA Research Institute of Clinical Laboratory Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "PLA Research Institute of Clinical Laboratory Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            },
            {
                "name": "YU Wei",
                "org": "PLA Research Institute of Clinical Laboratory Medicine,Jinling Hospital,Nanjing ,Jiangsu,China"
            }
        ],
        "venue": "Journal of Medical Postgraduates",
        "year": 2009
    },
    "5fKT4stn": {
        "id": "5fKT4stn",
        "title": "The soil nitrogen mineralization under four typical ecosystem in Qilian Mountains",
        "abstract": "The effects of varying soil temperature and water content on soil nitrogen mineralization are related to the response of terrestrial ecosystems to climate change. Qilian Mountains which is the typical mountains, situated on the northern border of Qinghai-Tibet plateau, is the venerable and sensitive region to climate change. To understand the effects of varying soil temperature and changing in water content on the decomposition of soil nitrogen, an anaerobic incubation experiment with orthogonal experiment in an artificial climatic chamber was contacted, and the effects of temperature, soil water content, soil depth, and mountain altitudes on the soil nitrogen mineralization under alpine meadows, mountainous forest, desert steppe, and arid steppe in Qilian Mountains were investigated. Based on the range of soil nitrogen mineralization, the effects of the altitudes on soil nitrogen mineralization was the highest, next were the effects of changing in soil water content and soil temperature. Based on the range of soil nitrogen mineralization ratio, the effects of soil temperature and altitudes on the soil nitrogen mineralization ratio were the highest. The effects of altitude on soil nitrogen mineralization was significant (p<0.05), and the effects of altitude , soil temperature, and the interaction of soil water content and temperature and soil depth on soil nitrogen mineralization ratio were all significan(tP<0.10).The soil nitrogen mineralization ratio was higher in 35 ℃ than in 5 ℃, while the difference of soil nitrogen mineralization and its ratio were not significant among different soil water content (p<0.05). The soil nitrogen mineralization in altitudes of 3 000 m and 3 300 m were higher than in altitudes of 2 200 m and 2 800 m, respectively, and it was higher in altitude of 2 800 m than in altitude of 2 200 m (p<0.05). The soil nitrogen mineralization ratio in altitude of 3 000 m was higher than in altitudes of 2 200 m and 3 300 m (p<0.05). The soil nitrogen mineralization ratio under mountainous forest and arid steppe were higher than that under alpine meadows or desert steppe. Based on the soil nitrogen mineralization rate, the Q10 was lower from 5 ℃ to 15 ℃ or 15 ℃ to 25 ℃ than from 25 ℃ to 35 ℃ .Based on the soil nitrogen mineralization rate ratio, Q10 was higher from 5 ℃ to 15 ℃ than from 15 ℃ to 25 ℃ or from 25 ℃ to 35 ℃, and it was higher from 15 ℃ to 25 ℃ than from 25 ℃ to 35 ℃. The results showed that soil nitrogen mineralization under mountainous forest or alpine meadows was higher than that under desert steppe or arid steppe, while the soil nitrogen mineralization ratio under mountainous forest or arid steppe was higher than that under desert steppe or alpine meadows.",
        "keywords": [
            "Qilian mountains",
            "desert steppe",
            "mineralization of soil nitrogen",
            "mountainous forest",
            "alpine meadows",
            "arid steppe"
        ],
        "authors": [
            {
                "name": "WU Jianguo",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "AI Li",
                "org": " Chinese Academy of Environmental Sciences, Beijing , China"
            },
            {
                "name": "CHANG Xuexiang",
                "org": " Cold and arid Regions Environmental and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 7300, China"
            }
        ],
        "venue": "Ecology and Environment",
        "year": 2007
    },
    "c4Jz7Qg1": {
        "id": "c4Jz7Qg1",
        "title": "Training Students,Science Research,Serving Society——The Establishment and Three Abilities of Nantong University Industry Process Control Lab",
        "abstract": "Combining with the establishment of Nantong University industry process control lab,this paper introduces the method that universities establish high level labs combining with enterprises.The lab plays the important functions in training students,science research,and serving society.Practice shows that can resolve the outlay of labs construction and speed the exerting of universities' three functions.At one time,bring up the potential users,upgrading the repute and acceterating development will be gained for correltive enterprises.",
        "keywords": [
            "DCS",
            "serving society",
            "science research",
            "training students"
        ],
        "authors": [
            {
                "name": "ZHANG Pei-jian",
                "org": "College of ELectronic & Information,Nantong University,Nantong ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of ELectrical Engineering,Nantong University,Nantong ,China"
            }
        ],
        "venue": "Journal of Electrical & Electronic Education",
        "year": 2006
    },
    "C6ALRgld": {
        "id": "C6ALRgld",
        "title": "Nitrogen Content in Soil Particulate Fraction and Its Relationship to the Elevation and the Vegetation",
        "abstract": "Nitrogen content of soil particulate fractions and its relationship to the vegetation and the elevation in Qilian Mountains were investigated. The results showed that the ratio of soil particulate fractions, soil particulate organic matter-nitrogen(PON) ratio, nitrogen content of soil particulate fractions, soil PON content did not significantly change with the altitude. The ratio of soil particulate fraction in 0～15 cm soil depth at 3 000 m,3 200 m and 3 500 m of shady slope, or 3 800 m of sunny slope, or that in 15～35 cm soil depth at 3 200 m,3 500 m of shady slope,or 2 800 m of semi-shady slope was the highest among the all elevations slope aspects and soil depths. PON ratio in 0～15 cm soil depth at 3 000 m and 3 200 m of shady slope,or 3 300 m and 3 800 m of sunny slope, or that in 15～35 cm soil depth at 3 300 m of sunny slope, or 3 000 m of shady slope was also the highest. The nitrogen content of PON in 0～15 cm at 3 600 m of shady slope was the lowest, while the nitrogen content of PON in 0～15 cm at 3 800 m of sunny slope,or 2 800 m of half shady slope, or that in 15～35 cm at 3 400 m of shady slope, or 3 300 m of sunny slope was the highest. The nitrogen content of soil particulate fraction in 0～15 cm soil depth at 3 400 m of shady slope, or 3 300 m and 3 800 m of sunny slope,or that in 15～35 cm under 3 400 m of shady slope and 3 300 m of sunny slope was the highest. There were also significant effects of vegetation on the ratio of soil particulate fraction, the ratio of soil PON, soil PON and nitrogen content of soil particulate fraction. The ratio of soil particulate fraction in 0～15 cm soil depth forest or in shrub meadows was the highest, and the difference for this ratio between in forest and shrub meadows or between in desert steppe and arid steppe were not significant, and that in 15～35 cm soil depth in forest, shrub meadows or arid steppe was the highest. While there were no significant difference for the ratio of soil particulate fraction among in forest, shrub meadows and steppe. The ratio of PON in different soil depth in forest and alpine meadows were the highest, and there were no significant difference for the ratio among under shrub meadows, steppe and arid steppe in 0～15 cm soil depth, and the ratio in steppe or arid steppe in 15～35 cm soil depth were the lowest (p<0.05). The nitrogen content of soil particulate fraction in different soil depth in shrub meadows was the highest, and that in desert steppe or arid steppe was the lowest. The nitrogen content of soil PON in different soil depth under forest or shrub meadows was the highest, while that in desert steppe or arid steppe was the lowest, and there were no significant difference for the nitrogen content among forest, alpine meadows and shrub meadows. The ratio of soil particulate fraction, nitrogen content of soil particulate fraction, soil PON content and soil PON ratio all increased with increasing total soil nitrogen content (p<0.02), and soil PON content increased with increasing nitrogen content of soil particulate fraction (p<0.001), and ratio of soil PON increased with increasing soil PON content (p<0.05).The results showed that the soil unprotected soil nitrogen content increased with increasing elevation, generally, and unprotected soil nitrogen ratio in forest and meadows was the highest among the all different types of vegetations.",
        "keywords": [
            "Qilian Mountains",
            "altitude",
            "soil particulate fraction nitrogen",
            "vegetation",
            "soil particulate organic matter-nitrogen",
            "total soil nitrogen"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Chinese research Academy of Environmental Science Beijing "
            },
            {
                "name": "Ai Li",
                "org": "Chinese research Academy of Environmental Science Beijing ;Beijing University of Science and Technology Beijing "
            }
        ],
        "venue": "Scientia Silvae Sinicae",
        "year": 2008
    },
    "Ky43pqyL": {
        "id": "Ky43pqyL",
        "title": "Ecological Dynamics in Fragmented Landscapes",
        "abstract": "Landscapes will likely become increas- ingly fragmented for biological organisms and ecological processes as the human population and its demands for resources continue to escalate. Landscape fragmentation results in habitat loss and alterations in the composition and spatial arrangement of landscape ele- ments, consequently affecting population and ecosystem processes. Thus, to protect biodi- versity and ecosystem functioning and to un- derstand how nature works in the changing world, we must understand how organisms, populations, communities, and ecosystems interact with spatially heterogeneous land- scapes in which they reside -- that is, ecologi- cal dynamics in fragmented landscapes. This paper discusses the effects of landscape frag- mentation on population and ecosystem proc- esses as well as major approaches to studying these effects.",
        "keywords": [
            "spatial heterogeneity",
            "habitat loss"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Arizona State University"
            }
        ],
        "venue": "",
        "year": 2009
    },
    "cC5hj0Jb": {
        "id": "cC5hj0Jb",
        "title": "Three-dimensional virtual reality simulation of periarticular tumors using Dextroscope reconstruction and simulated surgery: a preliminary 10-case study.",
        "abstract": "Dextroscope® three-dimensional (3D) imaging has been extensively used to generate virtual reality (VR) workspaces for neurosurgery and laparoscopy, but few applications have been reported for orthopedic surgery. Here, we investigated orthopedic periarticular tumor surgery planning and anatomical characteristics using a Dextroscope.Patients undergoing surgery for periarticular tumors (n=10) between October 2008 and June 2010 were enrolled and presurgically subjected to computed tomography (CT), magnetic resonance imaging (MRI), and MRI angiography (MRI-A). Imaging data were transferred and integrated in a Dextroscope to produce a VR simulation. The presurgical 3D anatomical reconstructions and intraoperative anatomical characteristics (virtual vs. actual data) and surgical approach (virtual vs. actual situation) measurement and subjective appearance were compared.Anatomical characteristics in the area of interest and tumor diameters in all 3 planes (superior-inferior, medial-lateral, and anteroposterior) were consistent between virtual and actual data (3.92±1.22, 1.96±0.53, and 1.73±0.44 vs. 3.92±1.13, 1.91±0.44, and 1.81±0.41; P=0.99, 0.24, and 0.09, respectively). However, the virtual surgical situations were inconsistent with the actual intraoperative situation in many cases, leading to complications. The resolutions of the original CT, MRI, and MRI-A images directly correlated with 3D simulation quality, with soft tissues most poorly represented. Tumor tissue imaging quality in 3D varied extensively by tumor type.Anatomical structures of periarticular tumors can be reconstructed using the Dextroscope system with good accuracy in the case of simple fenestration, increasing treatment individualization, surgical competence level, and potentially reducing intraoperative complications. However, further specialization of VR tools for use in orthopedic applications that involve specialized tools and procedures, such as drilling and implant placement, are urgently need.",
        "keywords": [
            "young adult",
            "computer simulation",
            "imaging"
        ],
        "authors": [
            {
                "name": "JingSheng Shi",
                "org": ""
            },
            {
                "name": "Jun Xia",
                "org": ""
            },
            {
                "name": "YiBing Wei",
                "org": ""
            },
            {
                "name": "SiQun Wang",
                "org": ""
            },
            {
                "name": "JianGuo Wu",
                "org": ""
            },
            {
                "name": "FeiYan Chen",
                "org": ""
            },
            {
                "name": "GangYong Huang",
                "org": ""
            },
            {
                "name": "Jie Chen",
                "org": ""
            }
        ],
        "venue": "Medical science monitor : international medical journal of experimental and clinical research",
        "year": 2014
    },
    "90gOdQQh": {
        "id": "90gOdQQh",
        "title": "Shape Optimization of the Airbag Launching Slipway",
        "abstract": "The aspects of the shape of the airbag launching slipway are analyzed in this paper, and many forms are discussed. Both of the methods of hydrostatics and hydrodynamics are used to calculate the airbag launching, to study the effect on the safety of the airbag launching caused by many factors such as the forms of the slipways, the location of airbags, the slope of the slipways and sea level, etc. In the example of two 20,000 DWT bulk cargo, the appropriate forms of the shapes of the airbag launching slipway are brought up by comparison of many methods and series of calculation.",
        "keywords": [
            "structural analysis",
            "ship launching",
            "slipway",
            "airbag launching"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": " College of Architectural & Civil Engineering, Zhejiang University of Technology, Hangzhou , China"
            },
            {
                "name": "YANG Jun",
                "org": " No.704 Research Institute, CSIC, Wuhan , China"
            },
            {
                "name": "ZHANG Kai-min",
                "org": " College of Architectural & Civil Engineering, Zhejiang University of Technology, Hangzhou , China"
            },
            {
                "name": "FENG Hua",
                "org": " College of Architectural & Civil Engineering, Zhejiang University of Technology, Hangzhou , China"
            }
        ],
        "venue": "Ship Engineering",
        "year": 2010
    },
    "6stOlGVP": {
        "id": "6stOlGVP",
        "title": "Design and Implementation of Environment and Security Terminal Based on GPRS",
        "abstract": "Using GPRS technology,combined with the ARM-μC/OS-Ⅱ platform,an intelligent monitoring device is designed to realize remote environment and security via GSM SMS.In the aspect of hardware,the system configuration,interface and peripherals were introduced while in the aspect of software,the realization of wireless telecommunications of GPRS under ARM-μC/OS-Ⅱ and the alarm information workflow is discussed.And the device has the characteristic of stabilization,credibility,mobility,easy operation and low costs etc.",
        "keywords": [
            "sensor",
            "structure",
            "real-time kernel system",
            "LPC2294",
            "GPRS"
        ],
        "authors": [
            {
                "name": "LI Wei",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "ZHANG Yi-chao",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "LU Ying",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Institute of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2008
    },
    "BVFONKW3": {
        "id": "BVFONKW3",
        "title": "Impacts of Protein and Fat Contents on Correlations of Quality Traits for Rapeseed",
        "abstract": "Impacts of protein and fat contents on the genetic correlations between glucosinolate content(GC) and other quality traits in rapeseed were analyzed by using unconditonal and conditional methods related to genetic effects from the diploid embryo nuclear genes,cytoplasm genes and diploid maternal plant nuclear genes.It is found that there is significant relationship between GC and protein content(PC) or fat content(FC) of rapeseed,and the conditional analysis method can be used to exclude the influences of PC and FC for further revealing the actual genetic relationships between glucosinolates and other quality traits.The conditional analysis reveals that the significant negative phenotypic and genotypic relationships between GC and palmitic acid content or the significant negative genotypic relationship between GC and linoleic acid content observed for the unconditional analysis are changed to significant positive relationships from conditional analysis after excluding the influences of PC.By excluding the influences of FC from conditional analysis,the significant positive phenotypic and genotypic relationships from the unconditional analysis between GC and eicosenoic acid content are translated to significant negative.Some significant phenotypic and/or genotypic relationships at the unconditional analysis are changed to non-significant at the conditional analysis between GC and erucic acid,oleic acid,linoleic acid or linolenic acid contents,which indicates that the level of PC or FC of rapeseed can affect the correlations between GC and the components of fatty acids.After eliminating the influences of PC or FC,the correlative components from different genetic systems reveal that the genetic effects of embryo,cytoplasm and maternal plant can significantly affect the conditional relationships of pairwise traits between the conditional GC and the fatty acids,especially for the embryo main effect,the cytoplasmic main effect and the maternal additive interaction effects.",
        "keywords": [
            "glucosinolates",
            "rapeseed",
            "quality trait",
            "fat content",
            "correlation",
            "protein content"
        ],
        "authors": [
            {
                "name": "Tu Jindong",
                "org": "Department of Agronomy,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou "
            },
            {
                "name": "Shi Yun",
                "org": "Department of Agronomy,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou "
            },
            {
                "name": "Wu Jianguo",
                "org": "Department of Agronomy,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou "
            },
            {
                "name": "Shi Chunhai",
                "org": "Department of Agronomy,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou "
            }
        ],
        "venue": "Journal of the Chinese Cereals and Oils Association",
        "year": 2009
    },
    "utGeRmMU": {
        "id": "utGeRmMU",
        "title": "Retinoic acid activates human inducible nitric oxide synthase gene through binding of RARalpha/RXRalpha heterodimer to a novel retinoic acid response element in the promoter.",
        "abstract": "Human inducible nitric oxide synthase (hiNOS) catalyzes nitric oxide (NO) which has a significant effect on tumor suppression and cancer therapy. Here we revealed the detailed molecular mechanism involved in the regulation of hiNOS expression induced by retinoic acid (RA). We showed that RARalpha/RXRalpha heterodimer was important in hiNOS promoter activation, hiNOS protein expression, and NO production. Serial deletion and site-directed mutation analysis revealed two half-sites of retinoic acid response element (RARE) spaced by 5bp located at -172 to -156 in the hiNOS promoter. EMSA and ChIP assays demonstrated that RARalpha/RXRalpha directly bound to this RARE of hiNOS promoter. Our results suggested the identification of a novel RARE in the hiNOS promoter and the roles of the nuclear receptors (RARalpha/RXRalpha) in the induction of hiNOS by RA.",
        "keywords": [
            "retinoid x receptors",
            "rxrγ",
            "9-cis retinoic acid",
            "rarβ",
            "retinoic acid",
            "rxrβ",
            "heterodimer",
            "rarγ",
            "human inducible nitric oxide synthase",
            "ra",
            "atra: all-trans ra",
            "9cra",
            "rxrα",
            "rare",
            "retinoic acid receptors",
            "nitric oxide",
            "rarα",
            "retinoic acid response element",
            "no",
            "hinos",
            "gene regulation",
            "mutation analysis",
            "chip",
            "molecular mechanics",
            "nuclear receptor",
            "protein expression",
            "receptors",
            "promoters"
        ],
        "authors": [
            {
                "name": "Fang Zou",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Yan Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Li Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Wei Wei",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Biochemical and biophysical research communications",
        "year": 2007
    },
    "Wcl1Xvth": {
        "id": "Wcl1Xvth",
        "title": "RBD mutations from circulating SARS-CoV-2 strains enhance the structural stability and human ACE2 affinity of the spike protein",
        "abstract": "Abstract  A novel coronavirus SARS-CoV-2 is associated with the current global pandemic of Coronavirus Disease 2019 (COVID-19). Bats and pangolins are suspected as the reservoir and the intermediate host. The receptor binding domain (RBD) of the SARS-CoV-2 S protein plays the key role in the tight binding to human receptor ACE2 for viral entry. Here, we analyzed the worldwide RBD mutants and found 18 mutant strains fell into 8 mutation types under high positive selection pressure during the spread. The equilibrium dissociation constant (K D ) of three types of RBD mutants emerging in Wuhan, Shenzhen, Hong Kong and France were two orders of magnitude lower than the prototype Wuhan-Hu-1 strain due to the stabilization of the beta-sheet scaffold of the RBD. This indicated that the mutated viruses may have evolved to acquire remarkably increased infectivity. Five France isolates and one Hong Kong isolate shared the same RBD mutation enhancing the binding affinity, which suggested that they may have originated as a novel sub-lineage. The K D values for the bat and the pangolin SARS-like CoV RBDs indicated that it would be difficult for bat SARS-like CoV to infect humans; however, the pangolin CoV is potentially infectious to humans with respect to its RBD. These analyses of critical RBD mutations provide further insights into the evolutionary trend of SARS-CoV-2 under high selection pressure. The enhancement of the SARS-CoV-2 binding affinity to ACE2 reveals a possible higher risk of more severe virus transmissions during a sustained pandemic of COVID-19 if no effective precautions are implemented. ",
        "keywords": "",
        "authors": [
            {
                "name": "Junxian Ou",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China;"
            },
            {
                "name": "Zhonghua Zhou",
                "org": "Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China;"
            },
            {
                "name": "Jing Zhang",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, Guangdong 510632, China;"
            },
            {
                "name": "Wendong Lan",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China;"
            },
            {
                "name": "Shan Zhao",
                "org": "Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China;"
            },
            {
                "name": "Jianguo Wu",
                "org": "Guangdong Provincial Key Laboratory of Virology, Institute of Medical Microbiology, Jinan University, Guangzhou, Guangdong 510632, China;"
            },
            {
                "name": "Donald Seto",
                "org": "Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, VA 20110, USA;"
            },
            {
                "name": "Gong Zhang",
                "org": "Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China;"
            },
            {
                "name": "Qiwei Zhang",
                "org": "Southern Medical University"
            }
        ],
        "venue": "bioRxiv",
        "year": 2020
    },
    "sroWHB2x": {
        "id": "sroWHB2x",
        "title": "Functional switch of viral protein HBx on cell apoptosis, transformation, and tumorigenesis in association with oncoprotein Ras.",
        "abstract": "The X protein (HBx) of hepatitis B virus (HBV) plays important roles in hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) during viral infection. In this study, we demonstrated that co-transfection of mouse embryo fibroblasts (STO) with HBx and activated Ras triggered apoptotic cell death, while HBx or activated Ras individually failed to induce apoptosis. In addition, STO cells were able to form colonies on soft agar after transfected with HBx or Ras, and cells co-transfected with both genes failed to transform. Moreover, nude mice injected with STO cells carrying either HBx or Ras could develop tumor, but tumor growth was inhibited by the injection of both STO cells harboring HBx and carrying Ras. These results suggested that HBx plays a role as a tumor inducer and stimulates neoplastic transformation of normal cells, but shifts its function to the induction of apoptosis in association with Ras.",
        "keywords": [
            "apoptosis",
            "hbx",
            "transformation",
            "tumorigenesis",
            "h-ras",
            "h ras",
            "cell death"
        ],
        "authors": [
            {
                "name": "Wei Wei",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, People's Republic of China"
            },
            {
                "name": "Wenjie Huang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, People's Republic of China"
            },
            {
                "name": "Ying Pan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, People's Republic of China"
            },
            {
                "name": "Fan Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "Cancer letters",
        "year": 2006
    },
    "wAtGGQ5s": {
        "id": "wAtGGQ5s",
        "title": "An Asymptotic Property of the Conditional Empirical Process",
        "abstract": "Let(Xi,Yi)(i=1,2,…,n) be samples from the population(X,Y)(X∈R1,Y∈Rq).Given Y=y,X has the conditional distribution M(x|y).Mnkn(x|y) is the kn nearest neighbor estimator of M(x|y).The asymptotic properties of the conditional empirical process is investigated: Sn(t,x,y)=k12n(Mnkn(x|y)-M(x|y)).Then under some regular conditions we show that for fixed y,Sn(t,x,y) converges weakly to a Gaussian process S(·).",
        "keywords": [
            "conditional distribution",
            "empirical process",
            "asymptotic property"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Department of Mathematics,Hunan College of Finance and Economics,Changsha ,China"
            }
        ],
        "venue": "Mathematics in Practice and Theory",
        "year": 2008
    },
    "Wh0ovDT1": {
        "id": "Wh0ovDT1",
        "title": "Research on the Evaluation Model of Dominant Characters of City",
        "abstract": "This text sets up six essential elements from numerous factors that affect the character of city and establishs a set of system of evaluation on dominant characters of city,then adopts regression model to analyze evolvement tractk of special features of city and the formation and development of new characters of city.",
        "keywords": [
            "character of city system of evaluation regression model"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Hunan College of Finance and Economics,Changsha,"
            },
            {
                "name": "Ai Yanlin",
                "org": "Hunan College of Finance and Economics,Changsha,"
            }
        ],
        "venue": "Mathematical Theory and Applications",
        "year": 2006
    },
    "KgjgolcE": {
        "id": "KgjgolcE",
        "title": "Determination of trace arsenic in naphtha by graphite furnace atomic absorption spectrometry",
        "abstract": "The determination of arsenic content in naphtha by GFAAS was studied with THF as solvent,and nickel nitrate as matrix modifier.The experimental results indicate that the linear range for arsenic is 0～50 μg/L,and recovery is 93%～104%.",
        "keywords": [
            "Graphite furnace atomic absorption spectrometry",
            "Arsenic content",
            "Naphtha"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            },
            {
                "name": "CHEN Xin-yue",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            },
            {
                "name": "SUN Yan-wei",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            },
            {
                "name": "MAN Qing-xiang",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            },
            {
                "name": "ZHANG Ying-yan",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            },
            {
                "name": "YU Xiao-zhan",
                "org": "Technology Center of Entry-exit Inspection & Quarantine Bureau of Liaoning,Dalian "
            }
        ],
        "venue": "Chinese Journal of Analysis Laboratory",
        "year": 2006
    },
    "dZmXunFT": {
        "id": "dZmXunFT",
        "title": "Impacts of land use and land cover change on regional climate: a case study in the agro-pastoral transitional zone of China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qian cao",
                "org": "beijing normal university"
            },
            {
                "name": "deyong yu",
                "org": "beijing normal university"
            },
            {
                "name": "m georgescu",
                "org": "arizona state university"
            },
            {
                "name": "zhe han",
                "org": "chinese academy of sciences"
            },
            {
                "name": "jianguo wu",
                "org": "beijing normal university"
            }
        ],
        "venue": "Environmental Research Letters",
        "year": 2015
    },
    "xQUqttah": {
        "id": "xQUqttah",
        "title": "A Review of the Economic, Social, and Environmental Impacts of China’s South–North Water Transfer Project: A Sustainability Perspective",
        "abstract": "China’s South–North Water Transfer Project (SNWTP) has the potential to transfer as much as 44.8 km3 year−1 of water from the Yangtze River basin to the Yellow River basin. However, the SNWTP has not been assessed from a sustainability perspective. Thus, in this study we evaluated the SNWTP’s economic, social, and environmental impacts by reviewing the English literature published in journals that are part of the Web of Science database. We then synthesized this literature using a Triple Bottom Line framework of sustainability assessment. Our study has led to three main findings: (1) whether the SNWTP is economically beneficial depends largely on model assumptions, meaning that economic gains at the regional and national level are uncertain; (2) the SNWTP requires the resettlement of hundreds of thousands of people and challenges existing water management institutions, suggesting possible social concerns beyond the short term; and (3) evidently large environmental costs in water-providing areas and uncertain environmental benefits in water-receiving areas together point to an uncertain environmental future for the geographic regions involved. Thus, the overall sustainability of SNWTP is seriously questionable. Although much work has been done studying individual aspects of SNWTP’s sustainability, few studies have utilized the multi-scale, transdisciplinary approaches that such a project demands. To minimize environmental risks, ensure social equity, and sustain economic benefits, we suggest that the project be continuously monitored in all three dimensions, and that integrated sustainability assessments and policy improvements be carried out periodically.",
        "keywords": "",
        "authors": [
            {
                "name": "Maxwell C. Wilson",
                "org": "Arizona State University"
            },
            {
                "name": "Xiao Yan Li",
                "org": "Beijing Normal University"
            },
            {
                "name": "Yu Jun Ma",
                "org": "Beijing Normal University"
            },
            {
                "name": "Andrew T. Smith",
                "org": "Life Sciences, School of (SOLS)"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, School of"
            }
        ],
        "venue": "Sustainability",
        "year": 2017
    },
    "UjOv4f1e": {
        "id": "UjOv4f1e",
        "title": "ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA Demethylation",
        "abstract": "A Nature Research Journal",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Dongjie Han",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Pan Pan",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Yanhua Cao",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            }
        ],
        "venue": "Scientific Reports",
        "year": 2016
    },
    "tzr38eMD": {
        "id": "tzr38eMD",
        "title": "Research of Image Pre-Processing in Vote Processing System",
        "abstract": "Vote processing system based on image recognition is an integrative device composed of imaging collection,transmission mechanism,computer and networking subsystems.Differs from other vote processing system which is based on the optical mark recognition,the system adopts methods,algorithms of optical character recognition techniques to recognize the handwritten symbols on votes.So this systerm is to recognize all kinds of handwritten symbols written by candidates such as “√、×、○、●、\\、/”,which belongs to off-line handwritten Chinese character recognition.In this paper,several important image processing techniques of vote information recognition are discussed,such as transforming of the color plate to gray plate,image binarization,skew correction,image smoothing,thinning,etc.In order to improve the rate of correct identification,put forward proper methods of image pre-processing.",
        "keywords": [
            "offline handwritten Chinese character",
            "pre-processing",
            "vote systerm",
            "image recognition"
        ],
        "authors": [
            {
                "name": "ZHANG Ting",
                "org": "School of Computer Sci.& Tech.,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Yuan-jun",
                "org": "Anhui Finance and Trade Technology College,Hefei ,China"
            },
            {
                "name": "HUANG Jun",
                "org": "School of Computer Sci.& Tech.,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Sci.& Tech.,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2007
    },
    "WZTf1hZ8": {
        "id": "WZTf1hZ8",
        "title": "Lower limb amputation and rehabilitation in total joint arthroplasties in the ipsilateral limb.",
        "abstract": "Degenerative joint disease is not uncommon in amputees and reaches the orthopedic surgeon when all other conservative methods to manage these patients have failed. Several case reports describing hip and knee arthroplasties in patients with hip and knee joint diseases or fractures with the distal part amputated, either in the contralateral or ipsilateral limb, exist in literature.This article focuses only on total knee and total hip arthroplasty in amputees who have had severe osteoarthritis of the ipsilateral hip and knee joints.Literature review.Literature search in database and summary of all the cases.All narratives indicate positive outcomes with improvement in physical function and quality of life.The reports suggest that slight modifications in surgical procedure and in the rehabilitation protocol as compared to other patients with joint arthroplasties can alleviate pain and make such patients ambulatory and gain maximum range of motion. Therefore, it appears that careful preoperative evaluation and planning tailored to suit individual cases maximizes postoperative good end results beneficial to the patients regardless of age or cause of osteoarthritis.",
        "keywords": [
            "orthopedic surgery",
            "total joint arthroplasties"
        ],
        "authors": [
            {
                "name": "Jingsheng Shi",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Siqun Wang",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Yibing Wei",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Feiyan Chen",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Guangyong Huang",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Jie Chen",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Licheng Wei",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Jianyuan Jiang",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China."
            },
            {
                "name": "Jun Xia",
                "org": "Huashan Hospital, Fudan University Shanghai Medical College, Shanghai, China xia_jun2010@126.com."
            }
        ],
        "venue": "Prosthetics and orthotics international",
        "year": 2014
    },
    "TO0IsXkx": {
        "id": "TO0IsXkx",
        "title": "Hepatitis B virus PreS1 facilitates hepatocellular carcinoma development by promoting appearance and self-renewal of liver cancer stem cells",
        "abstract": "Abstract   Hepatitis B virus (HBV) is a major etiologic agent of hepatocellular carcinoma (HCC). However, the molecular mechanism by which HBV infection contributes to HCC development is not fully understood. Here, we initially showed that HBV stimulates the production of cancer stem cells (CSCs)-related markers (CD133, CD117 and CD90) and CSCs-related genes (Klf4, Sox2, Nanog, c-Myc and Oct4) and facilitates the self-renewal of CSCs in human hepatoma cells. Cellular and clinical studies revealed that HBV facilitates hepatoma cell growth and migration, enhances white blood cell (WBC) production in the sera of patients, stimulates CD133 and CD117 expression in HCC tissues, and promotes the CSCs generation of human hepatoma cells and clinical cancer tissues. Detailed studies revealed that PreS1 protein of HBV is required for HBV-mediated CSCs generation. PreS1 activates CD133, CD117 and CD90 expression in normal hepatocyte derived cell line (L02) and human hepatoma cell line (HepG2 and Huh-7); facilitates L02 cells migration, growth and sphere formation; and finally enhances the abilities of L02 cells and HepG2 cells to induce tumorigeneses in nude mice. Thus, PreS1 acts as a new oncoprotein to play a key role in the appearance and self-renewal of CSCs during HCC development.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhixin Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Xuechen Dai",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Tianci Wang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Chengcheng Zhang",
                "org": ""
            },
            {
                "name": "Wenjun Zhang",
                "org": ""
            },
            {
                "name": "Wei Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan 430072, China"
            }
        ],
        "venue": "Cancer Letters",
        "year": 2017
    },
    "Tj5HZjnh": {
        "id": "Tj5HZjnh",
        "title": "In vitro inhibitory effects of papain on platelet aggregation",
        "abstract": "AIM:To observe the in vitro inhibitory effects of papain on platelet aggregation by washed platelet model,and explore the possible antithrombotic mechanism of papain. METHODS:Human washed platelets were mixed with different doses of papain. The maximal ratio of platelet aggregation induced by 5-adenosine liphosphate-disodium salt (ADP),arachidonic acid (AA),collagen and thrombin,respectively,was measured with platelet aggregation analyzer. The expressions of fibrinogen receptor(FIB-R) and p-selectin(CD62p) on external membrane of activated platelet were determinated with flow cytometry. The changes of factin cytoskeletal structure in activated platelet were analyzed by SDS-PAGE.Platelet rich plasma(PRP) of patients with primary hypertension(PH) or acute myocardiac infarction(AMI) was treated to determinate the levels of aggregation and FIB-R expression. RESULTS:Papain significantly inhibited platelet aggregation in a dose-dependent manner and reduced the levels of platelet aggregation,there was remarkably negative correlation between platelet aggregation level and papain dose(P<0.01). Papain notably inhibited FIB-R expression and decreased the levels of FIB-R expression activated by ADP in a dose-dependent manner. Papain reduced P-selectin expression on external membrane and lessened f-actins of platelet triggered by ADP. Papain significantly inhibited the levels of aggregation and FIB-R expression of platelets activated by ADP in patients with PH and AMI(P<0.01). CONCLUSION:Papain can inhibit the expression of fibrinogen receptor on external membrane of activated platelet and polymerization or release reaction,so the thrombocytic aggregation are inhibited in a dose-dependent manner,and papain has the effect of anti-thrombogenesis.",
        "keywords": [
            "platelet aggregation",
            "fibrinogen receptor",
            "P-selectin",
            "papain",
            "actin polymer"
        ],
        "authors": [
            {
                "name": "FEI Xian-ming",
                "org": " Central Laboratory,Zhejiang Provincial People's Hospital"
            },
            {
                "name": "ZHOU Yong-lie",
                "org": " Central Laboratory,Zhejiang Provincial People's Hospital"
            },
            {
                "name": "QI Jin-wen",
                "org": " Research Office of Pharmacology,Zhejiang Provincial People's Hospital,Hangzhou ,Zhejiang,China"
            },
            {
                "name": "WU Jian-guo",
                "org": " Central Laboratory,Zhejiang Provincial People's Hospital"
            },
            {
                "name": "QIU Lian-nv",
                "org": " Central Laboratory,Zhejiang Provincial People's Hospital"
            },
            {
                "name": "WANG Zhen-ni",
                "org": " Central Laboratory,Zhejiang Provincial People's Hospital"
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2009
    },
    "9zr50Gxv": {
        "id": "9zr50Gxv",
        "title": "The Effects of Temperature and Soil Water Content on the Seed Germination of Three Typical Plants Distributing in Qilian Mountains",
        "abstract": "Picea carassifolia,Potentilla fruticosa,Caragana jubata are dominant plants in Qilian Mountain.This paper discussed the effect of variational temperature and soil moisture on germination of three species at the simulative condition in laboratory.The results showed that soil moisture was the most important factor for germination of Picea carassifolia and Potentilla fruticosa,whose germination capacity and index were improved remarkably when the soil moisture was 22%. And enhancive rainfall would benefit for their germination.The proper temperature for germination of Picea carassifolia and Potentilla fruticosa was about 15～25℃.Lower temperature was good to improve the germination capacity and index of Caragana jubata.None of three species can germinate at 35℃.The difference of germination velocity of three species revealed their characteristic adaptation to the habitat.",
        "keywords": [
            "seed germination",
            "soil moisture",
            "climate change",
            "temperature"
        ],
        "authors": [
            {
                "name": "CHANG Wei",
                "org": ""
            },
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "LIU Yan-hong",
                "org": ""
            }
        ],
        "venue": "Chinese Horticulture Abstracts",
        "year": 2010
    },
    "p3tZgdGl": {
        "id": "p3tZgdGl",
        "title": "The mineralization of alpine meadow soil organic carbon and factors influencint it in the Qilian Mountain",
        "abstract": "The alpine meadow soil organic carbon(SOC) mineralization and its relationship with soil temperature,soil water content,soil depth and altitude in Qilian Mountains were analyzed by soil incubation in an orthogonal experiment.The impacts of soil temperature and soil depth on the cumulative SOC mineralization and its ratio were higher than that of soil water content,while the impacts of altitude were not significant.The cumulative SOC mineralization and its ratio were higher at 35℃ than at 5,15,or 25℃,while the differences between these three temperatures were not significant.SOC was higher in a soil water content of 30% or 40% than in 10% or 20%,but the differences between 30% and 40% or between 10% and 20% were not significant.SOC was higher in the 0-15 cm than in the 15-35 cm soil depth.The difference between different altitudes was not significant.The SOC mineralization rate and its ratio declined with increasing incubation time.The impacts of soil temperature and depth on the rate and its ratio of SOC mineralization were higher than the impacts of soil water content on them.The impacts of altitude were not significant.The rate and its ratio of SOC mineralization was higher at 35℃ than at 5,15,or 25℃,especially within 20 d of incubation.They were higher in soil water contents of 30% or 40% than in 10% or 20%,but the difference between 30% and 40% or between 10% and 20% were not significant,especially within 20 d of incubation.They were higher in the 0-15 cm than in the 15-35 cm soil depth.There was no significant difference between different altitudes.The first-order rate kinetic function fitted SOC mineralization well(R2>0.95).Based on cumulative SOC mineralization and the decomposition coefficient,the labile SOC pool was lowest at 5℃ and the decomposition coefficient was highest at 35℃,and the labile SOC pool was lower at 25℃ than at other temperatures.Based on the fraction of SOC mineralization,the labile SOC pool increased at higher temperatures and the decomposition coefficient at 35℃ was lower than at 15 or 25℃,which were lower than at 5℃.The Q10 indicated that the SOC mineralization rate increased with time and with every 10℃ increase.Based on the rate of SOC mineralization or its fraction,Q10 was 1-6 from 5 to 15℃ and 1-2 from 15 to 25℃.Based on the SOC mineralization rate,Q10 was 2-4 from 25 to 35℃ but based on the fraction of SOC mineralization rate,Q10 was 1.5-3.0 from 25 to 35℃.This study indicated that the mineralization of surface SOC under alpine meadows in Qilian Mountain would be greatly influenced by temperature change.",
        "keywords": [
            "mineralization of SOC",
            "Qilian Mountain",
            "alpine meadows"
        ],
        "authors": [
            {
                "name": "AI Li",
                "org": "The Science and Technology University of Beijing,Beijing ,China;Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "ZHU Gao",
                "org": "Xishui Conservation Site of Gansu Province Qilian Mountain Natural Reserve,Zhangye ,China"
            },
            {
                "name": "LIU Jian-quan",
                "org": "Gansu Province Qilian Mountain Natural Reserve,Zhangye , China"
            },
            {
                "name": "TIAN Zi-qiang",
                "org": "Chinese Academy of Environmental Sciences,Beijing ,China"
            },
            {
                "name": "CHANG Wei",
                "org": "The Science and Technology University of Beijing,Beijing ,China;Beijing Forestry University,Beijing ,China"
            },
            {
                "name": "XIA Xin",
                "org": "The Science and Technology University of Beijing,Beijing ,China"
            }
        ],
        "venue": "Acta Prataculturae Sinica",
        "year": 2007
    },
    "y1dNrp6h": {
        "id": "y1dNrp6h",
        "title": "Contribution of small RNA pathway components in plant immunity.",
        "abstract": "Small RNAs regulate a multitude of cellular processes, including development, stress responses, metabolism, and maintenance of genome integrity, in a sequence-specific manner. Accumulating evidence reveals that host endogenous small RNAs and small RNA pathway components play important roles in plant immune responses against various pathogens, including bacteria, fungi, oomycetes, and viruses. Small-RNA-mediated defense responses are regulated through diverse pathways and the components of these pathways, including Dicer-like proteins, RNA-dependent RNA polymerases, Argonaute proteins, and RNA polymerase IV and V, exhibit functional specificities as well as redundancy. In this review, we summarize the recent insights revealed mainly through the examination of two model plants, Arabidopsis and rice, with a primary focus on our emerging understanding of how these small RNA pathway components contribute to plant immunity.",
        "keywords": [],
        "authors": [
            {
                "name": "Jang-Kyun Seo",
                "org": "Department of Plant Pathology &amp; Microbiology, University of California, Riverside, CA, USA."
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Yifan Lii",
                "org": ""
            },
            {
                "name": "Yi Li",
                "org": ""
            },
            {
                "name": "Hailing Jin",
                "org": ""
            }
        ],
        "venue": "Molecular plant-microbe interactions : MPMI",
        "year": 2013
    },
    "yYXvFfhb": {
        "id": "yYXvFfhb",
        "title": "Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection.",
        "abstract": "Interleukin (IL)-32 is a recently described pro-inflammatory cytokine that has been reported to be induced by bacteria treatment in culture cells. Little is known about IL-32 production by exogenous pathogens infection in human individuals.In this study, we found that IL-32 level was increased by 58.2% in the serum samples from a cohort of 108 patients infected by influenza A virus comparing to that of 115 healthy individuals. Another pro-inflammatory factor cyclooxygenase (COX)-2-associated prostaglandin E2 was also upregulated by 2.7-fold. Expression of IL-32 in influenza A virus infected A549 human lung epithelial cells was blocked by either selective COX-2 inhibitor NS398 or Aspirin, a known anti-inflammatory drug, indicating IL-32 was induced through COX-2 in the inflammatory cascade. Interestingly, we found that COX-2-associate PGE(2) production activated by influenza virus infection was significantly suppressed by over-expression of IL-32 but increased by IL-32-specific siRNA, suggesting there was a feedback mechanism between IL-32 and COX-2.IL-32 is induced by influenza A virus infection via COX-2 in the inflammatory cascade. Our results provide that IL-32 is a potential target for anti-inflammatory medicine screening.",
        "keywords": [
            "transfection",
            "engineering",
            "chemistry",
            "medicine",
            "biology",
            "physics",
            "interleukins"
        ],
        "authors": [
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Yan Liu",
                "org": ""
            },
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": ""
            },
            {
                "name": "Rui Gong",
                "org": ""
            },
            {
                "name": "Ying Pan",
                "org": ""
            },
            {
                "name": "Sahibzada T Rasool",
                "org": ""
            },
            {
                "name": "Yecheng Gao",
                "org": ""
            },
            {
                "name": "Lei Kang",
                "org": ""
            },
            {
                "name": "Qian Hao",
                "org": ""
            },
            {
                "name": "Guiqing Peng",
                "org": ""
            },
            {
                "name": "Yanni Chen",
                "org": ""
            },
            {
                "name": "Xin Chen",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            }
        ],
        "venue": "PloS one",
        "year": 2008
    },
    "pKIcC5Up": {
        "id": "pKIcC5Up",
        "title": "The distributions of Chinese yak breeds in response to climate change over the past 50 years.",
        "abstract": "The effects of prior climate change on yak breed distributions are uncertain. Here, we measured changes in the distributions of 12 yak breeds over the past 50 years in China and examined whether the changes could be attributed to climate change. Long-term records of yak breed distribution, grey relational analysis, fuzzy sets classification techniques and attribution methods were used. Over the past 50 years, the distributions of several yak breeds have changed in multiple directions, mainly shifting northward or westward, and most of these changes are related to the thermal index. Driven by climate change over the past years, the suitable range and the distribution centers of certain yak breeds have changed with fluctuation and have mainly shifted northward, eastward or southward. The consistency of observed versus predicted changes in distribution boundaries or distribution centers is higher for certain yak breeds. Changes in the eastern distribution boundary of two yak breeds over the past 50 years can be attributed to climate change.",
        "keywords": [
            "attribution",
            "biodiversity",
            "climate change",
            "grey relation analysis",
            "yak breed"
        ],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "Chinese Res Inst Environm Sci, Ctr Climate Change, 8 Da Yang Fang, Beijing 100012, Peoples R China"
            }
        ],
        "venue": "ANIMAL SCIENCE JOURNAL",
        "year": 2015
    },
    "A5Kt94Ev": {
        "id": "A5Kt94Ev",
        "title": "Hot Spot Stress Analysis of Hull Longitudinals",
        "abstract": "Based on the method of hot spot stress,a typical form of hull longitudinals is analyzed in this paper by MSC.Patran /Nastran software.This paper discusses the influences of four different factors on stress concentration factor(SCF)for hot spots of ship connections,and summarizes their variation trend line.",
        "keywords": [
            "longitudinals",
            "finite element analysis",
            "hot spot stress",
            "stress concentration factor"
        ],
        "authors": [
            {
                "name": "Gui Zhifei",
                "org": ""
            },
            {
                "name": "Wu Jianguo",
                "org": ""
            },
            {
                "name": "Zhan Zhihu",
                "org": ""
            }
        ],
        "venue": "Ship & Boat",
        "year": 2010
    },
    "4N3hugaG": {
        "id": "4N3hugaG",
        "title": "Local Asymptotic Behavior of W_n(x,y)in the Stochastic Process",
        "abstract": "In this paper the local asymptotic behavior of the stochastic process is investigated: Wn(x , y). The conclusion that for fixed point y0, Wn(x , y) ,converges weakly to a Gaussian process is proved.",
        "keywords": [
            "Gaussian process",
            "stochastic process",
            "asymptotic property"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": " Hunan College of Finance and Economies, Changsha , China"
            }
        ],
        "venue": "Jilin Normal University Journal (Natural Science Edition)",
        "year": 2005
    },
    "q5zYmzYu": {
        "id": "q5zYmzYu",
        "title": "Genotypic variation of mineral elements contents in rice (Oryza sativa L.)",
        "abstract": "Mineral nutrition of potassium (K), calcium (Ca), sodium (Na), magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu) and manganese (Mn) are important for human health. The method of inductively coupled plasma mass spectrometry (ICP-MS) was employed to determinate the contents of K, Ca, Na, Mg, Fe, Zn, Cu and Mn in milled rice (Oryza sativa L.) of 274 rice genotypes. The results showed that the visible difference could be found for the contents of eight elements in milled rice among rice genotypes studied. It existed the possibility to select the genotype(s) with abundant of mineral nutrient from the genetic resource. Meanwhile, the contents of mineral elements in brown rice were significantly higher than those in milled rice. The averages of K, Mn and Cu contents of indica rice were significantly lower than those of japonica rice, while no significant difference was found for other five element contents between indica and japonica rice genotypes. The average contents of Na and Cu in non-glutinous rice genotypes were higher than those in glutinous ones, whereas the averages of K and Mn contents in non-glutinous rice genotypes were lower in present experiment. Additionally, the K, Ca and Mg contents of milled rice from white brown rice were significantly higher than those from red brown rice, and Ca content of milled rice from white brown rice was also visibly higher than that from black brown rice. For microelements, significant difference was observed for Zn content between milled rice from red and white brown rice, or between milled rice from red and black brown rice. Some genotypes with abundant mineral nutrient in milled rice had been selected and could be used in rice nutrient breeding. © 2008 Springer-Verlag.",
        "keywords": [
            "Genotypes",
            "ICP-MS",
            "Mineral nutrition",
            "Rice (Oryza sativa L.)"
        ],
        "authors": [
            {
                "name": "ShuLi Jiang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Nguyen B. Thang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ying Feng",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Xiao'e Yang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "European Food Research and Technology",
        "year": 2008
    },
    "1qQQMK0s": {
        "id": "1qQQMK0s",
        "title": "Climate change and landscape fragmentation jeopardize the population viability of the Siberian tiger (Panthera tigris altaica)",
        "abstract": "The Amur tiger, a flagship species of the boreal forest ecosystem in Russian Far East and northeastern China, has declined dramatically in population and geographic distribution due to human caused habitat fragmentation and poaching over the past century. The fate of this largest feline species will also be influenced by the worsening impacts of climate change. In this paper we assess the possible effects of climate change (three scenarios from the 2007 IPCC Report) on the Amur tiger by integrating species distribution modeling (SDM) and population viability analysis (PVA). We projected the potential and realized suitable habitat distributions to examine the impacts from anthropogenic factors, and evaluated the changes of suitable habitat and extinction risk for 100 years under climate change. The realized suitable habitat was projected to be more severely fragmented than the potential suitable habitat because of human-related factors. The potential suitable habitat would expand northward under all climate change scenarios considered. However, the tiger population would suffer the largest decline and highest extinction risk in the next 100 years under the worst climate change scenario (A1B) even though the size of potential habitat would be greatest. Under climate change, the tiger population could persist for the next century only if the size and quality of current habitat patches would remain intact. In addition, our study demonstrated that using SDM alone could grossly overestimate the geographic distribution of the Amur tiger, and that coupling SDM and PVA could provide important insights into conservation planning to mitigate the effects of climate change.\n",
        "keywords": [
            "Amur tiger",
            " Species distribution modeling (SDM)",
            " Population viability analysis (PVA)",
            " Climate change",
            " Russian Far East",
            " China"
        ],
        "authors": [
            {
                "name": "yu tian",
                "org": "State Key Laboratory of Environmental Criteria and Risk Assessment,Chinese Research Academy of Environmental Science,Beijing,China"
            },
            {
                "name": "jianguo wu",
                "org": "School of Life Sciences and Global Institute of Sustainability,Arizona State University,Tempe,USA"
            },
            {
                "name": "tianming wang",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology & School of Life Sciences,Beijing Normal University,Beijing,China"
            },
            {
                "name": "jianping ge",
                "org": "State Key Laboratory of Earth Surface Processes and Resource Ecology & School of Life Sciences,Beijing Normal University,Beijing,China"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2014
    },
    "502EUuYm": {
        "id": "502EUuYm",
        "title": "Rice stripe virus NS3 protein regulates primary miRNA processing through association with the miRNA biogenesis factor OsDRB1 and facilitates virus infection in rice.",
        "abstract": "MicroRNAs (miRNAs) are small regulatory RNAs processed from primary miRNA transcripts, and plant miRNAs play important roles in plant growth, development, and response to infection by microbes. Microbial infections broadly alter miRNA biogenesis, but the underlying mechanisms remain poorly understood. In this study, we report that the Rice stripe virus (RSV)-encoded nonstructural protein 3 (NS3) interacts with OsDRB1, an indispensable component of the rice (Oryza sativa) miRNA-processing complex. Moreover, the NS3-OsDRB1 interaction occurs at the sites required for OsDRB1 self-interaction, which is essential for miRNA biogenesis. Further analysis revealed that NS3 acts as a scaffold between OsDRB1 and pri-miRNAs to regulate their association and aids in vivo processing of pri-miRNAs. Genetic evidence in Arabidopsis showed that NS3 can partially substitute for the function of double-stranded RNA binding domain (dsRBD) of AtDRB1/AtHYL1 during miRNA biogenesis. As a result, NS3 induces the accumulation of several miRNAs, most of which target pivotal genes associated with development or pathogen resistance. In contrast, a mutant version of NS3 (mNS3), which still associated with OsDRB1 but has defects in pri-miRNA binding, reduces accumulation of these miRNAs. Transgenic rice lines expressing NS3 exhibited significantly higher susceptibility to RSV infection compared with non-transgenic wild-type plants, whereas the transgenic lines expressing mNS3 showed a less-sensitive response. Our findings revealed a previously unknown mechanism in which a viral protein hijacks OsDRB1, a key component of the processing complex, for miRNA biogenesis and enhances viral infection and pathogenesis in rice.",
        "keywords": "",
        "authors": [
            {
                "name": "Zheng Lijia",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Zhang Chao",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Shi Chaonan",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Wang Yu",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Zhou Tong",
                "org": "Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China."
            },
            {
                "name": "Sun Feng",
                "org": "Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China."
            },
            {
                "name": "Wang Hong",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Zhao Shanshan",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Qin Qingqing",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Qiao Rui",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Ding Zuomei",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Wei Chunhong",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            },
            {
                "name": "Xie Lianhui",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Wu Jianguo",
                "org": "State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Fujian Province Key Laboratory of Plant Virology, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, China."
            },
            {
                "name": "Li Yi",
                "org": "The State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences, Peking University, Beijing, China."
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2017
    },
    "un4iy39X": {
        "id": "un4iy39X",
        "title": "Understanding the Patterns and Drivers of Air Pollution on Multiple Time Scales: The Case of Northern China",
        "abstract": "China’s rapid economic growth during the past three decades has resulted in a number of environmental problems, including the deterioration of air quality. It is necessary to better understand how the spatial pattern of air pollutants varies with time scales and what drive these changes. To address these questions, this study focused on one of the most heavily air-polluted areas in North China. We first quantified the spatial pattern of air pollution, and then systematically examined the relationships of air pollution to several socioeconomic and climatic factors using the constraint line method, correlation analysis, and stepwise regression on decadal, annual, and seasonal scales. Our results indicate that PM was the dominant air pollutant in the Beijing–Tianjin–Hebei region, while PM and PM were both important pollutants in the Agro-pastoral Transitional Zone (APTZ) region. Our statistical analyses suggest that energy consumption and gross domestic product (GDP) in the industry were the most important factors for air pollution on the decadal scale, but the impacts of climatic factors could also be significant. On the annual and seasonal scales, high wind speed, low relative humidity, and long sunshine duration constrained PM accumulation; low wind speed and high relative humidity constrained PM accumulation; and short sunshine duration and high wind speed constrained O accumulation. Our study showed that analyses on multiple temporal scales are not only necessary to determine key drivers of air pollution, but also insightful for understanding the spatial patterns of air pollution, which was important for urban planning and air pollution control.",
        "keywords": [
            "Air quality index",
            "Constraint line analysis",
            "Correlation analysis",
            "PM2.5",
            "Stepwise regression"
        ],
        "authors": [
            {
                "name": "Yupeng Liu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science,Beijing Normal University,Beijing,ChinaSchool of Life Sciences and School of Sustainability,Arizona State University,Tempe,USA"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science,Beijing Normal University,Beijing,China"
            },
            {
                "name": "Ruifang Hao",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Faculty of Geographical Science,Beijing Normal University,Beijing,China"
            }
        ],
        "venue": "Environmental Management",
        "year": 2018
    },
    "YKh4j4RA": {
        "id": "YKh4j4RA",
        "title": "Forest degradation deepens around and within protected areas in East Asia",
        "abstract": "Forest degradation in protected areas has been monitored around the world with remote sensing data, but degradation processes undetectable by widely used satellite sensors have been largely overlooked. Increased human pressures and socioeconomic development make forest protection more challenging, particularly for forest ecosystems that lie across national borders because of the differences in national socioeconomic policies and conditions within them. Here with Landsat data, Google Earth images, and field observations, we show that, in two adjacent biosphere reserves across the border of China and North Korea, over one half of primary forest landscapes have been deteriorated by exploitive uses, including seed harvesting and systematic logging. The combined effects of detectable and hidden degradation processes have further damaged forest ecosystems in the core areas in the two biosphere reserves, threatening sustainable biodiversity conservation in the region. It is urgent to develop cross-border collaborative conservation strategies that can help combat both detectable and hidden degradation processes at a regional scale. (C) 2010 Elsevier Ltd. All rights reserved.",
        "keywords": [
            "Forest degradation",
            "Temperate forest",
            "Biosphere reserves",
            "Cross-border conservation",
            "Remote sensing"
        ],
        "authors": [
            {
                "name": "Lina Tang",
                "org": "Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Environm & Hlth, Xiamen 360021, Peoples R China"
            },
            {
                "name": "Guofan Shao",
                "org": "Purdue Univ, Dept Forestry & Nat Resources, W Lafayette, IN 47907 USA"
            },
            {
                "name": "Zhengji Piao",
                "org": "Jilin Changbai Mt Acad Sci, Jilin 133613, Antu County, Peoples R China"
            },
            {
                "name": "Limin Dai",
                "org": "Chinese Acad Sci, Inst Appl Ecol, Shenyang 110016, Peoples R China"
            },
            {
                "name": "Michael A. Jenkins",
                "org": "Purdue Univ, Dept Forestry & Nat Resources, W Lafayette, IN 47907 USA"
            },
            {
                "name": "Shaoxian Wang",
                "org": "Jilin Changbai Mt Acad Sci, Jilin 133613, Antu County, Peoples R China"
            },
            {
                "name": "Gang Wu",
                "org": "Chinese Acad Sci, State Key Lab Urban & Reg Ecol, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Arizona State Univ, Sch Life Sci, Tempe, AZ 85287 USA"
            },
            {
                "name": "Jingzhu Zhao",
                "org": "Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Environm & Hlth, Xiamen 360021, Peoples R China"
            }
        ],
        "venue": "BIOLOGICAL CONSERVATION",
        "year": 2010
    },
    "AfFbVi3q": {
        "id": "AfFbVi3q",
        "title": "Molecular epidemiological characteristics of dengue virus carried by 34 patients in Guangzhou in 2018.",
        "abstract": "Dengue fever is a major worldwide public health problem that, as estimated by the WHO, causes epidemics in over 100 countries, resulting in hundreds of millions of dengue virus (DENV) infections every year. In China, dengue fever mainly occurs in coastal areas. Recurring dengue outbreaks were reported by Guangdong Province almost every year since the first epidemic in 1978. DENV infections persisted in Guangzhou in consecutive years since 2000, with the dengue epidemic reaching a historical peak in 2014. Because Guangzhou is one of the largest cities for opening up in China, understanding the epidemiological characteristics of dengue fever in the city can hopefully provide a significant basis for developing effective dengue prevention strategies. In this study, a total of 34 DENV strains, including 29 DENV-1 strains and 5 DENV-2 strains, were isolated from a blood samples drawn from patients who were diagnosed with dengue fever by hospitals in Guangzhou during 2018. To explore the epidemiological characteristics of dengue fever, the envelope (E) gene obtained from the isolates was amplified for phylogenetic analysis. The results from the phylogenetic analysis showed that DENV in Guangzhou was mainly imported from Southeast Asian countries. Additionally, propagation paths based on phylogeographical analysis suggested potential local dengue transmission in Guangzhou.",
        "keywords": "",
        "authors": [
            {
                "name": "Feng Liao",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Huini Chen",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Jieliang Xie",
                "org": "School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Shaofeng Zhan",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Pan Pan",
                "org": "College of Life Sciences, WuHan university, Wuhan, China."
            },
            {
                "name": "Zizhao Lao",
                "org": "Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Yaohua Fan",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Lupin Lin",
                "org": "Guangzhou eighth People's Hospital, Guangzhou Medical University, Guangzhou, China."
            },
            {
                "name": "Yanni Lai",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Shuangfeng Lin",
                "org": "The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Institute of Medical Microbiology, Jinan University, Guangzhou, China."
            },
            {
                "name": "Xiaohong Liu",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            },
            {
                "name": "Geng Li",
                "org": "Laboratory Animal Center, Guangzhou University of Chinese Medicine, Guangzhou, China."
            }
        ],
        "venue": "PloS one",
        "year": 2019
    },
    "xqnaIPY2": {
        "id": "xqnaIPY2",
        "title": "Macrocalyxin A induces apoptosis by mitochondrial signaling pathway in HL-60 leukemia cells",
        "abstract": "AIM: To study the effects of macrocalyxin A(MA) on proliferation inhibition and apoptosis in HL-60 human leukemia cell line and explore its mechanisms.METHODS: Different concentrations of MA and different times of cultivation were used to treat HL-60 cell.The proliferation inhibition was analyzed by MTT assay.The cell apoptosis was analyzed by cell morphology,DNA agarose gel electrophoresis,DNA content and cell cycle analyzation,Annexin-V/PI and Hoechst 33258 fluorescence staining.The expressions of Bcl-2,Bax,Fas P53 and mitochondrial membrane protein were analyzed by flow cytometry,while the mitochondrial transmembrancepotential(ΔΨm) was labeled by dihydrorhodamin 123.RT-PCR method was used to study the Bcl-2,Bax,P53 and caspase-3 mRNA levels.RESULTS: MA could inhibit HL-60 cell proliferation viability within a certain range of treating time and dose,with a 24 h IC50 of 8.76 μg/mL,48 h of 7.17 μg/mL and 72 h of 7.14 μg/mL.A majority of HL-60 cells were arrested in G0/G1 phase.The HL-60 cells apoptosis was confirmed by type cell morphology,DNA fragment,sub-G1 phase and Annexin-Ⅴ/PI labeling method with a time and dose related manner.The expression of Bax was increased,and Bcl-2,P53 and fas were unchanged by the treatment of MA.MA could increase the expression of mitochondrial membrane protein and caspase-3 in a dose-dependent manner while the ΔΨm was reduced.CONCLUSION: MA can inhibit the proliferation and induce the apoptosis of HL-60 cells.The mechanisms associate with its up-regulation of Bax and the ratio of Bax/Bcl-2,decreasing the mitochondrial membrane potential,opening the mitochondrial membrane pore and activating caspase-3.",
        "keywords": [
            "mitochondria",
            "apoptosis",
            "leukemia",
            "macrocalyxin A"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": ""
            },
            {
                "name": "ZHOU Yong-lie",
                "org": ""
            },
            {
                "name": "XIA Da-jing",
                "org": ""
            },
            {
                "name": "XIA Jun",
                "org": ""
            },
            {
                "name": "QIU L",
                "org": ""
            },
            {
                "name": "WU Mao",
                "org": ""
            },
            {
                "name": "LIN Hui-jun",
                "org": ""
            },
            {
                "name": "FEI Xian-ming",
                "org": ""
            }
        ],
        "venue": "Chinese Journal of Clinical Pharmacology and Therapeutics",
        "year": 2009
    },
    "DYVJ6fdC": {
        "id": "DYVJ6fdC",
        "title": "Analysis of genetic and genotype x environment interaction effects from embryo, cytoplasm and maternal plant for oleic acid content of Brassica napus L.",
        "abstract": "The genetic effects including genetic main and genotype × environment interaction effects (GE) for oleic acid content of rapeseed (Brassica napus L.) were studied with eight parents and their F1 and F2 during 1998-1999 by using genetic model for quantitative traits of seed in diploid plant. The results indicated that the heredity of oleic acid content (OAC) of rapeseed was simultaneously controlled by diploid embryo nuclear genes, cytoplasmic genes and diploid maternal plant nuclear genes as well as their GE interaction effects. Genetic main effects for OAC were more important than GE interaction effects. The total narrow-sense heritability for OAC was high (77.5%), and the general heritabilities were found to be larger than the GE interaction heritabilities. The predicted genetic effects indicated that Huashuang 3 and Zhong R-888 were better than other parents for improving OAC of offspring. © 2004 Elsevier Ireland Ltd. All rights reserved.",
        "keywords": [
            "Genetic effect",
            "Heritability",
            "Oleic acid",
            "Quality",
            "Rapeseed (Brassica napus L.)"
        ],
        "authors": [
            {
                "name": "HaiZhen Zhang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Chunhai Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Yuling Ren",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Changtao Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Dongqing Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            },
            {
                "name": "YaoFeng Zhang",
                "org": "Chinese Academy of Agricultural Sciences(Chinese Academy of Agricultural Sciences),Beijing,China"
            }
        ],
        "venue": "Plant Science",
        "year": 2004
    },
    "4QEOw1Mt": {
        "id": "4QEOw1Mt",
        "title": "Effects of functional diversity loss on ecosystem functions are influenced by compensation.",
        "abstract": "Understanding the impacts of biodiversity loss on ecosystem functioning and services has been a central issue in ecology. Experiments in synthetic communities suggest that biodiversity loss may erode a set of ecosystem functions, but studies in natural communities indicate that the effects of biodiversity loss are usually weak and that multiple functions can be sustained by relatively few species. Yet, the mechanisms by which natural ecosystems are able to maintain multiple functions in the face of diversity loss remain poorly understood. With a long-term and large-scale removal experiment in the Inner Mongolian grassland, here we showed that losses of plant functional groups (PFGs) can reduce multiple ecosystem functions, including biomass production, soil NO -N use, net ecosystem carbon exchange, gross ecosystem productivity, and ecosystem respiration, but the magnitudes of these effects depended largely on which PFGs were removed. Removing the two dominant PFGs (perennial rhizomatous grasses and perennial bunchgrasses) simultaneously resulted in dramatic declines in all examined functions, but such declines were circumvented when either dominant PFG was present. We identify the major mechanism for this as a compensation effect by which each dominant PFG can mitigate the losses of others. This study provides evidence that compensation ensuing from PFG losses can mitigate their negative consequence, and thus natural communities may be more resilient to biodiversity loss than currently thought if the remaining PFGs have strong compensation capabilities. On the other hand, ecosystems without well-developed compensatory functional diversity may be much more vulnerable to biodiversity loss.",
        "keywords": [
            "biodiversity",
            "ecosystem functioning",
            "grassland ecosystem",
            "multifunctionality",
            "plant functional group",
            "removal experiment"
        ],
        "authors": [
            {
                "name": "Qingmin Pan",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China."
            },
            {
                "name": "Dashuan Tian",
                "org": "Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, CAS, 100101, Beijing, China."
            },
            {
                "name": "Shahid Naeem",
                "org": "Department of Ecology, Evolution, and Environmental Biology, Columbia University, 1200 Amsterdam Avenue, Schermerhorn Extension, New York, New York, 10027, USA."
            },
            {
                "name": "Karl Auerswald",
                "org": "Lehrstuhl für Grünlandlehre, Department of Plant Science, Technische Universität München, Alte Akademie 12, 85350, Freising-Weihenstephan, Germany."
            },
            {
                "name": "James J Elser",
                "org": "School of Life Sciences, Arizona State University, Tempe, Arizona, 85287, USA."
            },
            {
                "name": "Yongfei Bai",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China."
            },
            {
                "name": "Jianhui Huang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China."
            },
            {
                "name": "Qibing Wang",
                "org": "State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, The Chinese Academy of Sciences, 100093, Beijing, China."
            },
            {
                "name": "Hong Wang",
                "org": "Semiarid Prairie Agricultural Research Centre, Agriculture and Agri-Food Canada, Box 1030, Swift Current, Saskatchewan, S9H 3X2, Canada."
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences, Arizona State University, Tempe, Arizona, 85287, USA."
            },
            {
                "name": "Xingguo Han",
                "org": "State Key Laboratory of Forest and Soil Ecology, Institute of Applied Ecology, The Chinese Academy of Sciences, 110016, Shenyang, China."
            }
        ],
        "venue": "Ecology",
        "year": 2016
    },
    "tckaMwpo": {
        "id": "tckaMwpo",
        "title": "Video microscope recording of the dynamic course of thrombosis and thrombolysis of the retinal vein in rabbits.",
        "abstract": "The purpose of this study was to investigate the dynamic course of experimental thrombosis and thrombolysis of the retinal veins.Dynamic changes in the blood flow in the retinal veins were documented on a digital recorder through a microscope-mounted video camera and were analyzed on a monitor by video playback. Photochemical thrombus formation was induced by intravenous injection of 30% Rose Bengal followed by endoillumination of individual branch retinal veins of the eyes of 20 anesthetized pigmented rabbits. Subsequently, 10 rabbits were treated with an infusion in an ear vein of 3 mg/kg recombinant tissue plasminogen activator, whereas 10 control rabbits were administered with similar volumes of normal saline solution. Occlusion and recanalization were confirmed histologically and assessed by video microscopy.At the site exposed to light, photochemical injury resulted in the formation of a white thrombus, stagnation of blood flow, and subsequent complete venous occlusion in 20 rabbits. In this study, of the 10 animals in the recombinant tissue plasminogen activator treatment group, 9 (90%) showed evident thrombolysis, whereas none of the control group animals showed evident thrombolysis. The video showed that the massive thrombus disrupted into nonuniform fragments, which were quickly washed away by the blood flow, and the circulation was reestablished with no recurrence of secondary obstruction.In vivo data suggest that video microscopy may provide a visual approach for observing the dynamic changes occurring during experimental thrombus formation and lysis by the early administration of recombinant tissue plasminogen activator; this approach may assist in future investigation of thrombus research of ocular fundus.",
        "keywords": [],
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": ""
            },
            {
                "name": "Xiaoxu Zhou",
                "org": ""
            },
            {
                "name": "Yuntao Hu",
                "org": ""
            },
            {
                "name": "Taoran Zhang",
                "org": ""
            },
            {
                "name": "Zhizhong Ma",
                "org": ""
            },
            {
                "name": "Xiaorong Li",
                "org": ""
            },
            {
                "name": "Long Su",
                "org": ""
            },
            {
                "name": "Jiantao Wang",
                "org": ""
            },
            {
                "name": "Song Lin",
                "org": ""
            }
        ],
        "venue": "Retina (Philadelphia, Pa.)",
        "year": 2010
    },
    "LGHrVG5D": {
        "id": "LGHrVG5D",
        "title": "Linking ecosystem services with landscape history",
        "abstract": "The concept of ecosystem services (ES) has become widely used because it bridges ecology and economics and links nature to society. ES may evolve over time in dynamic landscapes driven by myriad processes. However, the consequences of changes in key ES has not been considered adequately in current ES research. Here we propose a framework for linking ES with landscape history, which can help us better understand the evolution of ES over time. We illustrate the framework by a case study from Switzerland. Both the capacity of landscapes to supply ES and the realization and recognition of key ES are likely to change over time. This insight should have important implications for landscape sustainability and related scenario studies.",
        "keywords": [
            "Ecosystem services",
            " Landscape history",
            " Land use and land cover",
            " Driving forces",
            " Landscape sustainability",
            " Scenarios",
            " Switzerland"
        ],
        "authors": [
            {
                "name": "matthias burgi",
                "org": "WSL Swiss Federal Institute for Forest Snow and Landscape Research,Birmensdorf,Switzerland"
            },
            {
                "name": "janet silbernagel",
                "org": "university of wisconsin madison"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "felix kienast",
                "org": "WSL Swiss Federal Institute for Forest Snow and Landscape Research,Birmensdorf,Switzerland"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2014
    },
    "DEIj8DwL": {
        "id": "DEIj8DwL",
        "title": "Quantifying spatiotemporal patterns of urban impervious surfaces in China: An improved assessment using nighttime light data",
        "abstract": "",
        "keywords": [
            "china",
            "ndvi"
        ],
        "authors": [
            {
                "name": "qun ma",
                "org": ""
            },
            {
                "name": "chunyang he",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            },
            {
                "name": "zhifeng liu",
                "org": ""
            },
            {
                "name": "qiaofeng zhang",
                "org": ""
            },
            {
                "name": "zexiang sun",
                "org": ""
            }
        ],
        "venue": "Landscape and Urban Planning",
        "year": 2014
    },
    "axDOLQZb": {
        "id": "axDOLQZb",
        "title": "Innovative Exploration and Experiment of Talent-cultivating Pattern of “College-Business Cooperative Cultivation,Academic&Technical Double Certification and 4-Open Patterns” of College Education",
        "abstract": "Sustainably cultivating and producing a large number of high technical talents who can adjust to the local economic development is not only the necessary need in the twelfth Five-Year-Plan period in which Zhangjiagang City takes the lead in accomplishing modernization,promotes all-round innovative development and accelerates economic transformation,but also an important subject which Shazhou Professional Institute of Technology is facing with.However,producing high technical talents who can adjust to the local economic development requires the innovation in cultivating the talents;Innovating in cultivating talents necessarily needs innovation of talent-cultivation pattern.In order to meet Zhangjiagang’s needs for high technical talents from the past through the present to the future,Shazhou Professional Institute of Technology should make continuous efforts to deepen the reform of talent-cultivating pattern and vigorously advance the construction of its connotation.",
        "keywords": [
            "dual subject",
            "high technical talents",
            "cultivating pattern",
            "double certification"
        ],
        "authors": [
            {
                "name": "CHEN Zai-tie",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "WANG Jie",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "YI Shun-ming",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2012
    },
    "7k7fAb0n": {
        "id": "7k7fAb0n",
        "title": "A simultaneous iris angiography technique in pigmented rabbits.",
        "abstract": "To report a simultaneous iris angiography (IA) technique combined with the use of indocyanine green (ICG) and fluorescein sodium (FS) in pigmented rabbits.15 rabbits were randomly divided into 3 groups according to the dye doses: the dose of the lower-volume group was 2 mg FS and 2 mg ICG; the dose of the moderate-volume group was 5 mg FS and 5 mg ICG, and the dose of the higher-volume group was 8 mg FS and 8 mg ICG. Fifteen IAs were performed by a confocal scanning laser ophthalmoscope and a rapid localization technique giving a flat-on image.Simultaneous digital angiography provided two kinds of a fully dynamic video of iris vessels fluorescein in all pigmented rabbits, which is the same in pigmented and albino rabbits and no vascular pattern was hidden by the iris stromal pigment. Furthermore, dye doses influenced the IA effect in rabbits. The lower-volume dye can demonstrate iris vessels, without obvious leakage, which, however, extinguish rapidly after 10-15 s. In the higher-volume group, vascular imaging lasted longer, but subsequently significant FS and ICG leakage appeared as streams on the surface of the iris until the dye disappeared from the iris vessels; the diffuse and intense aqueous fluid lasted 1 day. The moderate-volume dye displayed vessels clearly by ICG for 300 s, without leakage; FS clear vessels were maintained for about 15-20 s and the structure of the iris became fuzzy due to quick leakage.Simultaneous IA with a rapid localization technique allows high-quality imaging of the pigmented rabbits and the moderate dosage of 5 mg FS and 5 mg ICG is preferred for best visualization.",
        "keywords": [
            "confocal scanning laser ophthalmoscope",
            "iris angiography",
            "pigmented rabbit",
            "rapid localization technique"
        ],
        "authors": [
            {
                "name": "Xiao-Xu Zhou",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Ai-Hua Liu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Song Lin",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            }
        ],
        "venue": "Ophthalmic research",
        "year": 2012
    },
    "emBvEMMt": {
        "id": "emBvEMMt",
        "title": "An improved response surface method based on weighted regression for reliability analysis",
        "abstract": "In order to overcome these problems that the response surface method(RSM) is time consuming for large-scale applications and sometimes shows large errors in the calculation of the sensitivity of the reliability index with respect to random variables,this study proposes an efficient and improved RSM based on weighted regression.In the proposed method,a linear RSF is constructed at first and a quadratic RSF is formed using the axial experimental points selected from the reduced region where the MPFP is likely to exist.The RSF is updated successively by adding one new experimental point to the previous set of experimental points and giving higher weight to the experimental points closer to the most probable failure point(MPFP).Numerical examples are presented to demonstrate the improved accuracy and computational efficiency of the proposed method compared to the RSM based on a double weighted regression.",
        "keywords": [
            "response surface method",
            "weighted regression",
            "RSM function",
            "structural reliability"
        ],
        "authors": [
            {
                "name": "HONG Fei",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            }
        ],
        "venue": "Journal of Zhejiang University of Technology",
        "year": 2012
    },
    "ginVd4eA": {
        "id": "ginVd4eA",
        "title": "Further education of financial staff in primary medical institutions",
        "abstract": "Objective to seek the approach to further education of financial staff in primary medical institutions.Methods We made a whole sample survey of 694 financial staff of primary medical institutions in Xuzhou area and processed the collected data by rank-sum test.Results There were many weaknesses in further education of financial staff in primary medical institution in Xuzhou area.Conclusion Financial staff's further education in primary medical institution is to be improved.",
        "keywords": [
            "primary medical institution",
            "further education",
            "financial staff"
        ],
        "authors": [
            {
                "name": "GAO Chang",
                "org": "College of Health Policies,Nanjing Medical University,Nanjing,Jiangsu ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Health Policies,Nanjing Medical University,Nanjing,Jiangsu ,China"
            }
        ],
        "venue": "Chinese Rural Health Service Administration",
        "year": 2013
    },
    "MU5mTO4W": {
        "id": "MU5mTO4W",
        "title": "Characterizing air pollution patterns on multiple time scales in urban areas: a landscape ecological approach",
        "abstract": "Quantifying the spatiotemporal patterns of air pollution in urban areas is essential for studying ecological processes, environmental quality, and human health in cities. To adequately characterize or monitor air pollution patterns, one important issue is scale because the concentrations of air pollutants are temporally dynamic and spatially heterogeneous. Our research addresses the scale issue in air quality monitoring and analysis by considering the following research questions: (1) How does the spatial pattern of ozone change with the temporal scale of analysis? (2) How does the spatial pattern of PM change with the temporal scale of analysis? (3) What implications do these scale effects have for designing and evaluating air pollution monitoring networks? We systematically examined these questions based on data from official air pollution monitoring networks in the Phoenix metropolitan region, Arizona, USA. Our results showed that spatial patterns of both ozone and PM may change substantially with the temporal scale of analysis. Ozone patterns at broader (but not finer) temporal scales were more consistent across years, and exhibited a more uniform, regionalized pattern. PM patterns were less consistent across years than ozone, and exhibited a more localized effect. Spatial patterns of PM also varied seasonally. Our study demonstrates that it is critically important to consider the temporal and spatial scales in designing or evaluating air monitoring networks in particular and in conducting air pollution research in general.",
        "keywords": [
            "Air pollution",
            "Spatial pattern of air pollutants",
            "Monitoring network",
            "Ozone",
            "PM",
            "10",
            "Scale effects",
            "Phoenix metropolitan region"
        ],
        "authors": [
            {
                "name": "ronald pope",
                "org": "arizona state university"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            }
        ],
        "venue": "Urban Ecosystems",
        "year": 2014
    },
    "KA8ccDqC": {
        "id": "KA8ccDqC",
        "title": "Temporal variations in soil CO 2 efflux in an alpine meadow site on the Qinghai–Tibetan Plateau",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Jianguo Wu",
                "org": "The Center for Climate Change Chinese Research Academy of Environmental Sciences Beiyuan, Beijing China"
            }
        ],
        "venue": "Grassland Science",
        "year": 2019
    },
    "zufWXJMb": {
        "id": "zufWXJMb",
        "title": "Study on the Suction Infiltration Process of the Composite Aluminium Foam",
        "abstract": "The aluminium foam can be reinforced by compositing high hardness ZrO2 ceramic spheres.The paper parpared the composite aluminium foam by using the precuisor composed of the salt particals and ceramic spheres on the sution infiltration test.By orthogonal test,the paper analysed the influencing parameters on infiltration height including the preheating temperature(A),pouring temperature(B),seepage force(C),percentage composition of precuisor(D)and generalized that the degree of influence was A>C>B>D.Under the condition of expermemt lab,the influnce regularity of parameters on infiltraion heght and the selextivity scale were achieved,otherwise the paper discussed common defect and cause of prepartive sample.The research findings should establish a basement on the performance study of composite aluminium.",
        "keywords": [
            "composite material",
            "sution infiltration",
            "ZrO2 ceramic sphere",
            "aluminium foam"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "college of Materials Science and Engineering,Taiyuan Unversity of Science &Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Lu-cai",
                "org": "college of Materials Science and Engineering,Taiyuan Unversity of Science &Technology,Taiyuan Shanxi ,China"
            },
            {
                "name": "WANG Fang",
                "org": "college of Materials Science and Engineering,Taiyuan Unversity of Science &Technology,Taiyuan Shanxi ,China"
            }
        ],
        "venue": "Foundry Equipment and Technology",
        "year": 2011
    },
    "bcyKHFaG": {
        "id": "bcyKHFaG",
        "title": "Face Detection Based on Adaboost Algorithm and Facial Features",
        "abstract": "Face detection and location is the basis of face analysis and applications in many field.So one fast accurate and efficient face detection algorithm is of great significance.It proposes a human face detection by making use of facial features and Adaboost algorithm.First,search the regions where might exist faces by using skin color information.Then make use of some morphological to search the possible face blocks.Finally,Adaboost algorithm is used for fast decision on the candidate.Experiment result shows that the proposed algorithm is fast,and there is a better accuracy and robustness on copying with multi-profile,complex backgrounds face.",
        "keywords": [
            "candidate block",
            "face detection",
            "Adaboost algorithm",
            "eye",
            "skin color"
        ],
        "authors": [
            {
                "name": "HUANG Ge-feng",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Zhong",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2012
    },
    "9lP9csTL": {
        "id": "9lP9csTL",
        "title": "Determination of Trace Mercury Content in Naphtha by Cold Vapour-Atomic Absorption Spectroscopy",
        "abstract": "Mercury vapour in the naphtha was reduced under reaction with more reductant Tin(Ⅱ)chloride and rapidly determined by cold vapour Atomic absorption spectroscopy. The linear range is 0—50μg/L with relative standard deviation of 1.48%—1.56% and regression coefficient of 0.999,the recovery is 97.40%—101.0%.The result is in accord with UOP 938-2000.",
        "keywords": [
            "Cold Vapour Atomic Absorption Spectroscopy",
            "Naphtha",
            "Mercury Content"
        ],
        "authors": [
            {
                "name": "CHEN Xin-Yue",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "YU Xiao-Zhan",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "SUN Yan-Wei",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "WU Jian-Guo",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of Liaoning,Dalian,Liaoning ,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Spectroscopy Laboratory",
        "year": 2008
    },
    "fBaIsi4L": {
        "id": "fBaIsi4L",
        "title": "Disposable sutureless silicone contact lens ring for use with a self-sealing cannula system during vitrectomy.",
        "abstract": "",
        "keywords": [
            "contact lens",
            "pars plana vitrectomy",
            "silicone ring"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": ""
            },
            {
                "name": "Xiao-Xu Zhou",
                "org": ""
            },
            {
                "name": "Guo-Ling Sun",
                "org": ""
            },
            {
                "name": "Lu-Xia Chen",
                "org": ""
            },
            {
                "name": "Xiao-Rong Li",
                "org": ""
            },
            {
                "name": "Yun-Tao Hu",
                "org": ""
            },
            {
                "name": "Zhi-Zhong Ma",
                "org": ""
            }
        ],
        "venue": "Retina (Philadelphia, Pa.)",
        "year": 2010
    },
    "ndZnGp3x": {
        "id": "ndZnGp3x",
        "title": "Calculation for launching of a 19200 DWT bulk carrier with gasbags",
        "abstract": "According to ship hydrostatic principle,a hydraulic force calculation program is established to carry out the calculation for launching of a 19 200 DWT bulk carrier with gasbags.Calculation for displacement of gasbags and total longitudinal moment is carried out with nonlinear finite element program,so that the validity of self-program is approved.Structure stress analysis for the ship has been put up particularly with finite element program,the result shows that the launching of the 19 200 DWT bulk carrier with gasbags is safe.",
        "keywords": [
            "structure analysis",
            "launching with gasbags",
            "ship launching"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": ""
            },
            {
                "name": "Feng Hua",
                "org": ""
            },
            {
                "name": "Yang Jun",
                "org": ""
            },
            {
                "name": "Ma Jian",
                "org": ""
            }
        ],
        "venue": "Ship & Boat",
        "year": 2009
    },
    "OVQsZGUl": {
        "id": "OVQsZGUl",
        "title": "Landscape connectivity shapes the spread pattern of the rice water weevil: a case study from Zhejiang, China.",
        "abstract": "The spread of invasive species is a complex ecological process that is affected by both the biology of the species and the spatial structure of a landscape. The rice water weevil (Lissorhoptrus oryzophilus Kuschel), a notorious crop pest found in many parts of the world, is one of the most devastating invasive species in China, and has caused enormous economic losses and ecological damage. Little is known, however, as to how habitat and landscape features affect the spatial spread of this pest. Thus, the main goal of this study was to investigate the relationship between the observed spread pattern of L. oryzophilus and landscape structural factors in Zhejiang Province, China between 1993 and 2001. We quantified the invasive spread of the weevil in terms of both the proportion of infected area and spread distance each year as well as landscape structure and connectivity of rice paddies with landscape metrics. Our results showed that the spread of L. oryzophilus took place primarily in the southwest-northeast direction along coastal areas at a speed of about 36 km per year. The composition and spatial arrangement of landscape elements were key determinants of this unique spread pattern. In particular, the connectivity of early rice paddies was crucial for the invasive spread while other factors such as meteorological and geographical conditions may also have been relevant. To control the spread of the pest, we propose four management measures: (1) to implement a landscape-level planning scheme of cropping systems to minimize habitat area and connectivity for the pest, (2) to reduce the source populations at a local scale using integrated control methods, (3) to monitor and report invasive spread in a timely manner, and (4) to strengthen the quarantine system. To be most effective, all four management measures need to be implemented together through an integrated, multi-scaled approach.",
        "keywords": [
            "The rice water weevil",
            "Biological invasion",
            "Landscape connectivity",
            "Invasive spread",
            "Pest control",
            "China"
        ],
        "authors": [
            {
                "name": "Zhengjun Wang",
                "org": "College of Life Sciences, Capital Normal University, Beijing, 100048 China"
            },
            {
                "name": "Jianguo Wu",
                "org": "School of Life Sciences and Global Institute of Sustainability, Arizona State University, Tempe, AZ 85287, USA"
            },
            {
                "name": "Hanwu Shang",
                "org": "College of Life Science, China Jiliang University, Hangzhou, 310018 China"
            },
            {
                "name": "Jiaan Cheng",
                "org": "Institute of Applied Entomology, Zhejiang University, Hangzhou, 310029 China"
            }
        ],
        "venue": "Environmental management",
        "year": 2011
    },
    "MIqkiTNg": {
        "id": "MIqkiTNg",
        "title": "Bovine PrPC directly interacts with αB-crystalline",
        "abstract": "We used a bovine brain cDNA library to perform a yeast two-hybrid assay with bovine mature PrP C as bait. The screening result showed that αB-crystalline interacted with PrP C . The interaction was further evaluated both in vivo and in vitro with different methods, such as immunofluorescent colocalization, native polyacrylamide-gel electrophoresis, and IAsys biosensor assays. The results suggested that αB-crystalline may have the ability to refold denatured prion proteins, and provided first evidence that αB-crystalline is directly associated with prion protein.",
        "keywords": [
            "bse",
            "tse",
            "shsp",
            "prion",
            "transmissible spongiform encephalopathies",
            "bovine mature prp c",
            "αb-crystalline",
            "bovine spongiform encephalopathy",
            "cjd",
            "prp c",
            "small heat-shock protein",
            "small heat-shock proteins",
            "creutzfeldt–jacob disease",
            "protein interaction",
            "boprp c"
        ],
        "authors": [
            {
                "name": "Guihong Sun",
                "org": "Key Laboratory of Allergy and Immune-related Diseases, Centre for Medical Research, School of Medicine, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Mingxiong Guo",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Ao Shen",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Fanghua Mei",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Xiaoxue Peng",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Rui Gong",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Deyin Guo",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Jianguo Wu",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Po Tien",
                "org": "The Modern Virology Research Centre and State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China"
            },
            {
                "name": "Gengfu Xiao",
                "org": ""
            }
        ],
        "venue": "FEBS Letters",
        "year": 2005
    },
    "zCrdUexC": {
        "id": "zCrdUexC",
        "title": " Noninvasive Identification of Immune-Related Biomarkers in Hepatocellular Carcinoma.",
        "abstract": "Primary liver carcinoma is one of the most common malignant tumors with a poor prognosis. This study aims to uncover the potential mechanisms and identify core biomarkers of hepatocellular carcinoma (HCC). The HCC gene expression profile GSE49515 was chosen to analyze the differentially expressed genes from purified RNA of peripheral blood mononuclear cells, including 10 HCC patients and 10 normal individuals. GO and KEGG pathway analysis and PPI network were used, and the enrichment of the core genes out of 15 hub genes was evaluated using GEPIA and GSEA, respectively. We employed flow cytometry to count mononuclear cells to verify our opinions. In this analysis, 344 DEGs were captured, including 188 upregulated genes and 156 downregulated genes; besides that, 15 hub genes were identified. GO analysis and KEGG analysis showed the DEGs were particularly involved in immune response, antigen processing and presentation, and infection and inflammation. The PPI network uncovered 2 modules were also mainly involved in immune response. In conclusion, our analysis disclosed the immune subversion was the major signature of HCC associated closely with JUN, VEGFA, TNFSF10, and TLR4, which could be novel noninvasive biomarkers in peripheral blood and targets for early diagnosis and therapy of HCC.",
        "keywords": "",
        "authors": [
            {
                "name": "Ling Li",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Huijia Zhao",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Binyao Chen",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Kang Huang",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Zhuowen Hao",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Zhipeng Fan",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Gongpeng Sun",
                "org": "Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "College of Life Sciences of Wuhan University, State Key Laboratory of Virology, Wuhan, Hubei 430071, China."
            },
            {
                "name": "Ning Li",
                "org": "Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Hubei Key Laboratory of Cardiology, Wuhan, China."
            },
            {
                "name": "Qifa Ye",
                "org": "The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha 410013, China."
            },
            {
                "name": "Jiang Yue",
                "org": "Department of Pharmacology, Basic Medical School of Wuhan University, Wuhan 430071, China."
            }
        ],
        "venue": "Journal of oncology",
        "year": 2019
    },
    "c4JKiGaz": {
        "id": "c4JKiGaz",
        "title": "Single-chain intracellular antibodies inhibit influenza virus replication by disrupting interaction of proteins involved in viral replication and transcription.",
        "abstract": "Influenza A virus is responsible for influenza epidemics in avian and human populations and poses a great threat to human health. Many researches have been focused on the prevention and treatment of influenza A virus infection. The nucleoprotein (NP) of the virus is an important protein due to its ability to interact with a variety of viral and cellular factors and its role in the viral RNA synthesis. In this study, we have used the influenza A virus nucleoprotein as target for anti-viral therapy through a new approach. By screening a human single-chain intracellular antibody (intrabody) cDNA library using nucleoprotein as bait in a yeast antigen-antibody two-hybrid system, we have identified several intrabodies that specifically interact with the viral nucleoprotein. Interaction between nucleoprotein and anti-nucleoprotein intrabodies was further confirmed by mammalian two-hybrid analysis. Results showed that anti-nucleoprotein intrabodies changed their cellular distribution in association with the viral nucleoprotein. Further studies indicated that anti-nucleoprotein intrabodies abolished the accumulation of not only the complementary RNA and virion RNA but also messenger RNA of influenza virus. In addition, anti-nucleoprotein intrabodies significantly inhibited influenza A virus transcription and replication through blocking the interaction of nucleoprotein with the viral polymerase proteins, polymerase basic protein 1 and polymerase basic protein 2. Thus, this study not only provides a powerful tool for the study of viral protein's functions, but also opens a new potential avenue for the prevention and treatment of influenza virus infections.",
        "keywords": [
            "nucleoprotein",
            "intrabodies",
            "viral replication",
            "influenza virus",
            "protein interaction",
            "hybrid system",
            "messenger rna",
            "cdna library"
        ],
        "authors": [
            {
                "name": "Muhammad Mahmood Mukhtar",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China."
            },
            {
                "name": "Shengfeng Li",
                "org": ""
            },
            {
                "name": "Wei Li",
                "org": ""
            },
            {
                "name": "Ting Wan",
                "org": ""
            },
            {
                "name": "Yongxin Mu",
                "org": ""
            },
            {
                "name": "Wei Wei",
                "org": ""
            },
            {
                "name": "Lei Kang",
                "org": ""
            },
            {
                "name": "Sahibzada T Rasool",
                "org": ""
            },
            {
                "name": "Yibei Xiao",
                "org": ""
            },
            {
                "name": "Ying Zhu",
                "org": ""
            },
            {
                "name": "Jianguo Wu",
                "org": ""
            }
        ],
        "venue": "The international journal of biochemistry & cell biology",
        "year": 2009
    },
    "2rDGpgfe": {
        "id": "2rDGpgfe",
        "title": "Impacts of urbanization on summer climate in China: An assessment with coupled land-atmospheric modeling: IMPACTS OF URBANIZATION ON CLIMATE",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Qian Cao",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology; Beijing Normal University; Beijing China"
            },
            {
                "name": "Deyong Yu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology; Beijing Normal University; Beijing China"
            },
            {
                "name": "Matei Georgescu",
                "org": "School of Geographical Sciences and Urban Planning; Arizona State University; Tempe Arizona USA"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology; Beijing Normal University; Beijing China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability, State Key Laboratory of Earth Surface Processes and Resource Ecology; Beijing Normal University; Beijing China"
            }
        ],
        "venue": "Journal of Geophysical Research",
        "year": 2016
    },
    "QynaTLvH": {
        "id": "QynaTLvH",
        "title": "Design and implementation of scoring system based on image recognition system",
        "abstract": "This paper designs a scoring system that allows users to use any color pen,paper,pen or pencil in the general location of the graffiti,such as a fixed \"√\",\"╳\",\"○\" and other symbols to complete hand-written answer.By the scoring system uses image recognition technology to answer card image preprocessing,character recognition,statistical sub-divided to achieve grading automation.Experiments show that,due to structural similarity,the scoring system focused on the symbol recognition errors\"√\",\"╳\",while the symbol \"○\" Identification of the basic correct.",
        "keywords": [
            "scoring system",
            "character recognition",
            "image recognition"
        ],
        "authors": [
            {
                "name": "Zhang Zhan",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "Liu Zhengyi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            },
            {
                "name": "Wu Jianguo",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "Li Wei",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Microcomputer & Its Applications",
        "year": 2011
    },
    "dhOJKI7b": {
        "id": "dhOJKI7b",
        "title": "Effects of Enhanced UV-B Radiation on the Photosynthesis and Related Physiological Parameters of Straw-Yellow Gentian(Gentiana straminea Maxim)",
        "abstract": "The effects of enhanced UV-B radiation on the laminae net photosynthetic rate and related physiological parameters of strawyellow gentian(Gentiana straminea Maxim) were determined and analyzed by using 20 W and 40 W UV-B lamps to increase the UVB radiation.The results showed that air temperature in the studied area began to rise from 09:00 am and peaked at 14:00.The variation trend of leaf temperature was similar with that of the atmospheric saturated vapor pressure and air temperature on August 3rd,2008.The photosynthetic active radiation(PAR) intensity began increasing at 07:00 am,peaked at 13:00,and then decreased.The laminae net photosynthetic rate(Pn),stomata conductance(Gs),intercellular CO2 concentration(Ci),transpiration rate(E) and water use efficiency(WUE) of straw-yellow gentian were the highest under the control treatment,and lowest under 40 W UV-B lamp treatment.Pn was the highest from 08:00-10:00;Gs was the highest from 07:00-08:00;Ci was the highest at time of sunrise or sunset;E was the highest at 09:00-13:00 or 14:00-18:00;and,WUE was the highest after sunrise.Pn was positively related with Gs,leaf temperature,atmosphere temperature,PAR or atmospheric saturated vapor pressure deficit,and negatively related with Ci.The correlation coefficient between Pn and PAR was higher.Additionally,the results showed that Pn increased with increasing PAR when the PAR ranged from 0-800 μmol /(m2·s),but it varied little when the PAR ranged from 2200-3000 μmol /(m2·s).Gs and E increased with increasing PAR.Ci decreased with increasing PAR when the PAR ranged from 0-800 μmol /(m2·s).WUE increased with increasing PAR when the PAR ranged from 0-800 μmol/(m2·s),but decreased when PAR ranged from 800-3000 μmol/(m2·s).The results indicated that enhanced UV-B radiation would result in decreases of Pn,Gs,Ci,E or WUE of alpine meadows leaves.",
        "keywords": [
            "photosynthesis",
            "Qinghai-Tibet plateau",
            "UV-B radiation",
            "straw-yellow gentian",
            "alpine meadows"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing ,China"
            }
        ],
        "venue": "Research of Environmental Sciences",
        "year": 2010
    },
    "ZcCYAmyc": {
        "id": "ZcCYAmyc",
        "title": "Effects of Enhanced UV-B Radiation and Temperature Variation on the Response of Photosynthesis and Related Physiological Parameters of Straw-Yellow Gentian (Gentiana straminea Maxim.) to changing in Photosynthetical Active Radiation",
        "abstract": "This study describes the effects of temperature changes and enhanced UV-B radiation on net photosynthesis and related physiological parameter of straw-yellow gentian(Gentiana straminea Maxim.).Samples were analyzed using 20 W and 40 W UV-B lamps to increase UV-B radiation and with LI-6400 portable photosynthesis systems to change air temperature.Results show that net photosynthetic rate(Pn),stomata conductance(Gs),intercellular CO2 concentration(Ci),transpiration rate(E) and water use efficiency(WUE) of straw-yellow gentian was higher under control than that under 20W or 40 W UV-B lamp treatments,while Pn at 25℃ was higher than that at 15℃ under increasing UV-B radiation treatments in August or under controls in September.Additionally,E of straw-yellow gentian at 25℃ was higher than that at 15℃,while Gs,Ci or WUE of straw-yellow gentian at 25℃ was lower than that at 15℃ under increasing UV-B radiation treatments.Results also show that Pn of straw-yellow gentian increased with increasing photosynthetic active radiation(PAR) when the PAR ranged from 0~800 μmol·m-2·s-1,while maximizing when PAR ranged from 800~2200 μmol·m-2·s-1,but no change when the PAR ranged from 2200~3000 μmol·m-2·s-1.The Gs or E of straw-yellow gentian increases with increased the PAR.The Ci of straw-yellow gentian decreases with increased PAR when the PAR ranged from 0~800 μmol·m-2·s-1,but did not change when the PAR ranged from 800~3000 μmol·m-2·s-1.The WUE of straw-yellow gentian increases with increased the PAR when the PAR ranged from 0~800 μmol·m-2·s-1,and it decreases slowly when PAR ranged from 800~3000 μmol·m-2·s-1.Results indicate that enhanced UV-B radiation results in decreased Pn,Gs,Ci,E and WUE of alpine meadows leaves that would be influenced by temperature variation.",
        "keywords": [
            "Photosynthesis",
            "Qinghai-Tibet Plateau",
            "UV-B radiation change",
            "Alpine Meadows",
            "Straw-Yellow Gentian"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Chinese research academy of environmental sciences,Beijing ,China"
            }
        ],
        "venue": "Acta Agrestia Sinica",
        "year": 2010
    },
    "mk7hBLYJ": {
        "id": "mk7hBLYJ",
        "title": "Asymptotic Properties of Extrema of Certain Conditional Sample Functions",
        "abstract": "The characteristics of the extrema of some sample functions are investigated. The sample functions are in the form of ψ( x, Gnk(x | y) , where Gnk(x | y) is an estimation of G( x | y) in its k nearest neighborhood ( k-NN) . The conclusion is that under regular conditions, there exists a certain Gaussian process to which converges.",
        "keywords": [
            "Gaussian process",
            "Extrema",
            "Asymptotic property",
            "Sample function"
        ],
        "authors": [
            {
                "name": "WU Jian-Guo",
                "org": " Basic Department, Hunan College of Finance & Economics , Changsha  , China "
            }
        ],
        "venue": "Journal of Henan University of Science & Technology(Natural Science)",
        "year": 2006
    },
    "iMBE3dHh": {
        "id": "iMBE3dHh",
        "title": "GC-MS Analysis of the Essential Oil from Ultrafine-Powder of Ganoderma sinense by Supercritical CO_2 Fluid Extraction",
        "abstract": "Objective:Further to analysis chemical components in the essential oil(EO) of Ganoderma sinense.Methods:EO was extracted using Supercritical CO2 fluid extraction(SFE-CO2) technique from the ultrafine-powder of Ganoderma sinense,and detected by Gas chromatography-mass spectrometry(GC-MS).Results: 46 compounds were checked out from the EO extract(with 1.47% of extract rate,w/w),and 26 compounds(matching degree >83%) were identified representing 79.2% of the total EO,including n-Hexadecanoic acid,(E)-9-Octadecenoic acid methyl ester,(E)-9-Octadecenoic acid and(E,E)-2,4-Decadienal,9-Methyl-Z-10-tetradecen-1-ol acetate,1,8,8-trimethyl-2-(3-oxocyclo-pentenyl)-Tricyclo[3.2.1.0(2,4)]octane-3,3-dicarbonitrile,(Z)-9-Octadecenoic acid-2-hydroxy-1-(hydroxymethyl) ethyl ester and E-11-Hexadecen-1-ol and so on.Collusion: The results indicated that chemical components and their relative contents of the EO extracted by SFE-CO2 were different from that by steam distillation(SD) after ether refluxing.",
        "keywords": [
            "essential oil",
            "supercritical CO2 fluid extraction",
            "Ganoderma sinense",
            "Gas chromatography-mass spectrometry"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou, Fujian ,China"
            },
            {
                "name": "WANG Hong-yu",
                "org": "Institute of Edible and Medicinal Fungi,Fujian Academy of Agricultural Sciences,Fuzhou,Fujian ,China"
            },
            {
                "name": "WU Yan-bin",
                "org": "Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine,Fuzhou, Fujian ,China"
            },
            {
                "name": "CHEN Ti-qiang",
                "org": "Institute of Edible and Medicinal Fungi,Fujian Academy of Agricultural Sciences,Fuzhou,Fujian ,China"
            }
        ],
        "venue": "Fujian Journal of Agricultural Sciences",
        "year": 2012
    },
    "ybyqetbT": {
        "id": "ybyqetbT",
        "title": "On the Dreamlike Consciousness and Culture Interpretation of the Genius and Beauty Novels during the Kang Qian Period of the Qing Dynasty",
        "abstract": "The genius and beauty novels during the Kang Qian period not only introduce a great number of the direct description of the dream in the development of the plot,but also common outpour the dreamlike consciousness and the pessimistic feeling that are mainly about \"Life is but an empty dreams\".In the process of the specific nararative operation,the dreamlike consciousness show multiple conflicts.There is the cultural interpretation of the phenomenon of literature from the mentality of scholars,the impact of Buddhism thought and Taoism thought and so on.",
        "keywords": [
            "the Kang Qian Period",
            "the genius and beauty novels",
            "the dreamlike consciousness",
            "cultural interpretation"
        ],
        "authors": [
            {
                "name": "ZHOU Hua-nan",
                "org": "Department of Literature and History,Hunan First Normal College,Changsha,Hunan "
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Liberal Art,Hunan Normal University,Changsha,Hunan "
            }
        ],
        "venue": "Research of Chinese Literature",
        "year": 2011
    },
    "3WlCCjPr": {
        "id": "3WlCCjPr",
        "title": "Design and implementation of host software in voting system for election",
        "abstract": "To improve the efficiency of voting system for election based on the OCR technology,a design method of system host software is proposed.In this method,the host software and the software of ballot box are considered together.Election information is taken full account of.Ballot is designed according to some position data in paper ballot.Ballot format data are sended to the box.A series of functions are implemented in voting system for election.So,a set of host software is developed.By this method,the ballot layout may be more complicated,and because the software of ballot box is designed based on these ballot format data it has more high speed of locating in the course of recognition.The efficiency of voting system is improved,and this voting system is more comprehensive.",
        "keywords": [
            "host software",
            "ballot",
            "vote",
            "computer network",
            "data structure"
        ],
        "authors": [
            {
                "name": "HU Li-rui",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University, Hefei ,China;School of Computer Science and Technology,Nantong University,Nantong ,China;School of Computer Science and Technology,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education,Anhui University, Hefei ,China;School of Computer Science and Technology,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Design",
        "year": 2012
    },
    "qYsDnMZY": {
        "id": "qYsDnMZY",
        "title": "Research on Algorithm for Handwritten Character Recognition",
        "abstract": "Introduces the basic principles of pattern recognition, the recognition to handwritten characters and word, expatiates the process of pattern recognition, the format of image file, and describs the pattern recognition theory based on bitmap technology in detail, discusses the optimization of the classifier's feature space design , the criteria of classifier, the basic methods and the knowledge of discriminant functions, gives a principle on using template matching method to recognize image.",
        "keywords": [
            "handwritten Character",
            "Discriminant Function",
            "Template Matching",
            "Pattern Recognition"
        ],
        "authors": [
            {
                "name": "GAO Liang",
                "org": "Ministry of Education's Key Laboratory of Intelligence Computing and signal Processing, Anhui University, Hefei "
            },
            {
                "name": "WU Jian-guo",
                "org": "Ministry of Education's Key Laboratory of Intelligence Computing and signal Processing, Anhui University, Hefei "
            },
            {
                "name": "LU Ying",
                "org": "Ministry of Education's Key Laboratory of Intelligence Computing and signal Processing, Anhui University, Hefei "
            }
        ],
        "venue": "Modern Computer",
        "year": 2008
    },
    "ou0JYzFx": {
        "id": "ou0JYzFx",
        "title": "Intelligent Test System for Big Power and High Voltage Motor",
        "abstract": "A new intelligence test system for big power and high voltage motors is introduced. The constitution and principle of the system are given. This system uses the distributed control model that the upper computer uses CIMPLICITY and the lower computer uses VersaMax PLC. This system can make motors test automatically and data handle intelligently. The motionless and dynamic parameters of motors can be got easily. According to the parameters, the motor quality will be given automatically.",
        "keywords": [
            "high voltage motor intelligent test system CIMPLICITY"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Nantong University"
            }
        ],
        "venue": "Electrotechnical Application",
        "year": 2006
    },
    "NAwA7gIJ": {
        "id": "NAwA7gIJ",
        "title": "Comparison of disposable sutureless silicone ring and traditional metal ring in 23-gauge vitrectomy combined with cataract surgery.",
        "abstract": "The purpose of this prospective, interventional, comparative case series was to evaluate the efficiency and feasibility of a disposable sutureless silicone lens ring for corneal contact lens stabilization during combined 23-gauge vitrectomy and cataract surgery.We developed a ring consisting of a single silicone component with three footplates along the ring margin to fit cannulae for holding conventional contact lenses. Thirty eyes from 30 patients with cataract and vitreoretinal disease were included, and divided into two matched groups according to disease type and ring used. In Group A, we used a 23-gauge transconjunctival vitrectomy system and a disposable sutureless silicone lens ring (n = 15). In Group B, we used a 23-gauge transconjunctival vitrectomy system and a conventional metal lens ring (n = 15). The main outcome measures were: time required for vitrectomy preparation, rate of intraoperative corneal limbus bleeding, and limbus scar rate at the final follow-up visit.Thirty cases were successfully completed. The average vitrectomy preparation time was less in Group A than in Group B (P < 0.01), and the average preparation time saved was 3.94 minutes. None of the Group A patients had intraoperative bleeding or postoperative scarring, whereas all 15 Group B cases had bleeding and five had scarring. There was a statistically significant difference between Group A and Group B for these complications (P ≤ 0.05).This report demonstrates the advantages of using a sutureless silicone ring during combined 23-gauge vitrectomy and cataract surgery. Using this method could allow extra time for the surgeon to pay more attention to complex vitreoretinal procedures.",
        "keywords": [
            "cataract surgery",
            "contact lens",
            "pars plana vitrectomy",
            "silicone ring",
            "biomedical research",
            "bioinformatics"
        ],
        "authors": [
            {
                "name": "Jian-Guo Wu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Rui-Hua Wei",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Ai-Hua Liu",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Xiao-Xu Zhou",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Guo-Ling Sun",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            },
            {
                "name": "Xiao-Rong Li",
                "org": "Tianjin Medical University(Tianjin Medical University),Tianjin,China"
            }
        ],
        "venue": "Clinical ophthalmology (Auckland, N.Z.)",
        "year": 2011
    },
    "PnDpv5BK": {
        "id": "PnDpv5BK",
        "title": "Genetic and genotype × environment interaction effects analysis for erucic acid content in rapeseed ( ",
        "abstract": "Genetic main effects and genotype × environment (GE) interaction effects for erucic acid content (EAC) in rapeseed( L.) were analyzed for two year data by using the genetic models and corresponding statistical approaches for quantitative traits of diploid plant seeds. Eight parents were included in adiallel mating design in two environments. It was found that the embryo, cytoplasmic and maternal main effects and their GE interaction effects could simultaneously affect the performance of EAC, especially for the cytoplasmic and maternal effects. Since the amount of genetic main effects from the expression of genes in different genetic systems accounted for about 64.1%of the total genetic effects, EAC of rapeseed was mainly controlled by genetic main effects. The total narrow-sense heritability for EAC was 83.6% with the general heritability being 51.9% and the interaction heritability being 31.7%. It was suggested by the predicted genetic effects, that Tower and Youcai 601 were better than other parents for reducing EAC in rapeseed quality breeding.",
        "keywords": [
            "erucic acid",
            "genetic effect",
            "heritability",
            "quality",
            "rapeseed (",
            "Brassica napus",
            "L."
        ],
        "authors": [
            {
                "name": "Chunhai Shi",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Haizhen Zhang",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Changtao Li",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Yuling Ren",
                "org": "Department of Agronomy, College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,China"
            }
        ],
        "venue": "Euphytica",
        "year": 2003
    },
    "ZgcYUdzP": {
        "id": "ZgcYUdzP",
        "title": "HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection.",
        "abstract": "Enterovirus 71 (EV71) is an RNA virus that causes hand-foot-mouth disease (HFMD), and even fatal encephalitis in children. Although EV71 pathogenesis remains largely obscure, host immune responses may play important roles in the development of diseases. Recognition of pathogens mediated by Toll-like receptors (TLRs) induces host immune and inflammatory responses. Intracellular TLRs must traffic from the endoplasmic reticulum (ER) to the endolysosomal network from where they initiate complete signaling, leading to inflammatory response. This study reveals a novel mechanism underlying the regulation of TLR7 signaling during EV71 infection. Initially, we show that multiple cytokines are differentially expressed during viral infection and demonstrate that EV71 infection induces the production of proinflammatory cytokines through regulating TLR7-mediated p38 MAPK, and NF-κB signaling pathways. Further studies reveal that the expression of the endosome-associated protein hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is upregulated and highly correlated with the expression of TLR7 in EV71 infected patients, mice, and cultured cells. Virus-induced HRS subsequently enhances TLR7 complex formation in early- and late-endosome by interacting with TLR7 and TAB1. Moreover, HRS is involved in the regulation of the TLR7/NF-κB/p38 MAPK and the TLR7/NF-κB/IRF3 signaling pathways to induce proinflammatory cytokines and interferons, respectively, resulting in the orchestration of inflammatory and immune responses to the EV71 infection. Therefore, this study demonstrates that HRS acts as a key component of TLR7 signaling to orchestrate immune and inflammatory responses during EV71 infection, and provides new insights into the mechanisms underlying the regulation of host inflammation and innate immunity during EV71 infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Zhen Luo",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Maolin Ge",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qibin Geng",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Mingfu Tian",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Zhi Qiao",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Lan Bai",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Chengliang Zhu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Ying Xiong",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Fang Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Yingle Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, China."
            }
        ],
        "venue": "PLoS pathogens",
        "year": 2017
    },
    "kTwP4Tr2": {
        "id": "kTwP4Tr2",
        "title": "HoxA10 Facilitates SHP-1-catalized Dephosphorylation of p38 MAPK/STAT3 to Repress Hepatitis B Virus Replication by a Feedback Regulatory Mechanism.",
        "abstract": "Hepatitis B virus (HBV) infection is the leading cause of chronic hepatitis B (CHB), liver cirrhosis (LC), and hepatocellular carcinoma (HCC). This study reveals a distinct mechanism underlying the regulation of HBV replication. HBV activates the homeobox A10 (HoxA10) in human hepatocytes, leukocytes, peripheral blood mononuclear cells (PBMCs), HepG2-NTCP cells, leukocytes isolated from CHB patients, and HBV-associated HCC tissues. HoxA10 in turn represses HBV replication in human hepatocytes, HepG2-NTCP cells, and BABL/c mice. Interestingly, we show that during early HBV infection, p38 MAPK and STAT3 were activated to facilitate HBV replication, however, during late HBV infection, HoxA10 was induced to attenuate HBV replication. Detailed studies reveal that HoxA10 binds to p38 MAPK and recruits the SH2 containing protein tyrosine phosphatase 1 (SHP-1) to facilitate SHP-1 in catalyzing dephosphorylation of p38 MAPK/STAT3, and thereby attenuates p38 MAPK/STAT3 activation and HBV replication. Furthermore, HoxA10 binds to HBV EnhI/X promoter and competes with STAT3 in the binding of the promoter, and thereby repress HBV transcription. Taken together, HoxA10 attenuates HBV replication through repressing the p38 MAPK/STAT3 pathway by two approaches: HoxA10 interacts with p38 MAPK and recruits SHP-1 to repress HBV replication; HoxA10 binds to EnhI/X promoter and competes with STAT3 to attenuate HBV transcription. Thus, the function of HoxA10 is similar to the action of interferon (IFN) in term of inhibition of HBV infection; however, the mechanism of HoxA10-mediated repression of HBV replication is different from the mechanism underlying IFN-induced inhibition of HBV infection. Two billion people have been infected with HBV worldwide, about 240 million of infected patients developed into chronic hepatitis B (CHB), and 650,000 die each year from liver cirrhosis (LC) or hepatocellular carcinoma (HCC). This work elucidates a mechanism underlying the control of HBV replication. HBV infection activates HoxA10, a regulator of cell differentiation and cancer progression, in human cells and patients with CHB and HCC. HoxA10 subsequently inhibits HBV replication in human tissue culture cells and mice. Additionally, HoxA10 interacts with p38MAPK to repress the activation of p38MAPK and STAT3, and recruits and facilitates SHP-1 to catalyze dephosphorylation of p38MAPK and STAT3. Moreover, HoxA10 competes with STAT3 in the binding of HBV X promoter to repress HBV transcription. Thus, this work reveals a negative regulatory mechanism underlying the control of HBV replication and would provide new insights into the development of potential agents to control of HBV infection.",
        "keywords": "",
        "authors": [
            {
                "name": "Qingyu Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Qi Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Xuewu Zhang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Lei You",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wenbiao Wang",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Weiyong Liu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yang Han",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Chunqiang Ma",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Wei Xu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Junbo Chen",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Hua Yang",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Pin Wan",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yao Zhou",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Yingle Liu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            },
            {
                "name": "Kailang Wu",
                "org": "State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China."
            },
            {
                "name": "Ziwen Yang",
                "org": "Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Virology of Guangzhou, Institute of Medical Microbiology, Jinan University, Guangzhou 510632, China."
            }
        ],
        "venue": "Journal of virology",
        "year": 2019
    },
    "m9Ntp9tl": {
        "id": "m9Ntp9tl",
        "title": "SCALING WITH KNOWN UNCERTAINTY: A SYNTHESIS",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "JIANGUO WU",
                "org": "Arizona State University School of Life Sciences and Global Institute of Sustainability 85287-4501 Tempe AZ USA"
            },
            {
                "name": "HARBIN LI",
                "org": "Center for Forested Wetlands Research USDA Forest Service Southern Research Station 29414 Charleston SC USA"
            },
            {
                "name": "K. BRUCE JONES",
                "org": "U.S. Environmental Protection Agency 89193-3478 Las Vegas NV USA"
            },
            {
                "name": "ORIE L. LOUCKS",
                "org": "Miami University Department of Zoology 45056 Oxford OH USA"
            }
        ],
        "venue": "",
        "year": 2006
    },
    "jYWtahjP": {
        "id": "jYWtahjP",
        "title": "Mechanical change and clinical significance of model of pelvis and acetabulum loaded with different ways",
        "abstract": "AIM To analyze the three-dimensional finite element model by loading the model of pelvis and acetabulum with standing and sitting postures then to observe the change of relevant mechanical parameters. METHODS ① Moist acetabulum models were from the Staff Room of Anatomy  Second Military Medical University of Chinese PLA . Acetabulum an adult moist cadaver pelvis was obtained and performed CT scanning then we got the images of every slice. With the software ANSYS5.6 we construct the three-dimensional model of acetabulum which was divided into 121 239 nodes and 112 491 units. At the same time the united part of cacroiliac joint and pubis was locked. Acetabulum was loaded by simulating standing and the direction was along the neck force line of femur. The force was about 400 N half about 80 kg body mass. The Three-dimensional force distribution of acetabulum was analyzed after being loaded. ②Pelvic model In August 2004 a normal male adult was randomly selected and performed CT scanning from the third vertebra to the sciatic tuberodties the images obtained from CT scanning were constructed to three-dimensional model of pelvis with the software ANSYS5.6. The model was divided into 356 710 units. Bilateral sciatic tuberodties of normal pelvis were fixed. The pelvis was loaded by simulating sitting with a 500 N force opposite to Z-axis pressuring on lumbar vertebrae erectly. Stress distribution image was calculated through finite element analysis. RESULTS ① Big value stresses were distributed in rami ossis pubis rami ossis ischii square area articulationes sacroiliaca posterior wall of acetabulum of the acetabular model after the three-dimensional finite models were loaded by simulating standing and the mean equivalent stress of each unit was (11.578-23.437) Mpa. ② High value stress appeared in cacroiliac joint and sciatic tuberodties after the three -dimensional finite element model of pelvis was loaded by simulating sitting  and the mean equivalent stress of each unit was (15.734-20.286) Mpa. CONCLUSION Experimental results suggest that the internal fixation of pelvic and acetabular fractures should be emphasized in effective internal fixation aiming to satisfy early functional exercises in bed and avoiding early loading.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "ShuoGui Xu",
                "org": "Changhai Hospital(Changhai Hospital,Second Military Medical University,Second Military Medical University of Chinese PLA),Shanghai,China"
            },
            {
                "name": "Tong Da-ke",
                "org": "Department of Orthopaedics Changhai Hospital Second Military Medical University of Chinese PLA Shanghai  China"
            },
            {
                "name": "Su Jia-can",
                "org": "Department of Orthopaedics Changhai Hospital Second Military Medical University of Chinese PLA Shanghai  China"
            },
            {
                "name": "Zhang Chun-cai",
                "org": "Department of Orthopaedics Changhai Hospital Second Military Medical University of Chinese PLA Shanghai  China"
            },
            {
                "name": "Cai Zheng-dong",
                "org": "Department of Orthopaedics Changhai Hospital Second Military Medical University of Chinese PLA Shanghai  China"
            },
            {
                "name": "Wu Jian-guo",
                "org": "Research Center of Biomechanics Tongji University Shanghai  China"
            }
        ],
        "venue": "Chinese Journal of Clinical Rehabilitation",
        "year": 2006
    },
    "aer79cpU": {
        "id": "aer79cpU",
        "title": "MA15.02 Deep Learning Approach for Automated Tumor Cells Detection and Estimation of PD-L1 22C3 Assay Expression in Lung Adenocarcinoma",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "D. Lin",
                "org": ""
            },
            {
                "name": "J. Wu",
                "org": ""
            },
            {
                "name": "W. Sun",
                "org": ""
            },
            {
                "name": "C. Liu",
                "org": ""
            },
            {
                "name": "X. Liu",
                "org": ""
            },
            {
                "name": "Y. Zhang",
                "org": ""
            },
            {
                "name": "J. Zhang",
                "org": ""
            },
            {
                "name": "H. Wang",
                "org": ""
            },
            {
                "name": "X. Yang",
                "org": ""
            },
            {
                "name": "S. Ling",
                "org": ""
            }
        ],
        "venue": "Journal of Thoracic Oncology",
        "year": 2019
    },
    "EPyKyypQ": {
        "id": "EPyKyypQ",
        "title": "Impacts of Climate Change on Tibetan Lakes: Patterns and Processes.",
        "abstract": "High-altitude inland-drainage lakes on the Tibetan Plateau (TP), the earth’s third pole, are very sensitive to climate change. Tibetan lakes are important natural resources with important religious, historical, and cultural significance. However, the spatial patterns and processes controlling the impacts of climate and associated changes on Tibetan lakes are largely unknown. This study used long time series and multi-temporal Landsat imagery to map the patterns of Tibetan lakes and glaciers in 1977, 1990, 2000, and 2014, and further to assess the spatiotemporal changes of lakes and glaciers in 17 TP watersheds between 1977 and 2014. Spatially variable changes in lake and glacier area as well as climatic factors were analyzed. We identified four modes of lake change in response to climate and associated changes. Lake expansion was predominantly attributed to increased precipitation and glacier melting, whereas lake shrinkage was a main consequence of a drier climate or permafrost degradation. These findings shed new light on the impacts of recent environmental changes on Tibetan lakes. They suggest that protecting these high-altitude lakes in the face of further environmental change will require spatially variable policies and management measures.",
        "keywords": "",
        "authors": [
            {
                "name": "Dehua Mao",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Zongming Wang",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Hong Yang",
                "org": "Arizona State University"
            },
            {
                "name": "Huiying Li",
                "org": "Jilin University"
            },
            {
                "name": "Julian R. Thompson",
                "org": "University College London"
            },
            {
                "name": "Lin Li",
                "org": "Indiana University-Purdue"
            },
            {
                "name": "Kaishan Song",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Bin Chen",
                "org": ""
            },
            {
                "name": "Hongkai Gao",
                "org": "Arizona State University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            }
        ],
        "venue": "Remote Sensing",
        "year": 2018
    },
    "0jvEweqL": {
        "id": "0jvEweqL",
        "title": "Weak sustainability is not sustainable: Socioeconomic and environmental assessment of Inner Mongolia for the past three decades",
        "abstract": "Abstract   Inner Mongolia of China is distinguished by its size, expansive grasslands, and rich endowment of natural resources – particularly coal. Since China’s “Reform and Opening Up”, Inner Mongolia’s socioeconomic trajectory has resembled that of China as a whole: a rapid rise in GDP, urbanization, and human development. But behind this rosy picture, has Inner Mongolia really been on a sustainable trajectory? To address this question, we quantified the temporal patterns of socioeconomic growth, energy consumption, and food and water footprints of Inner Mongolia from 1987 to 2015. Our results show that during the past three decades Inner Mongolia’s per-capita income increased 8.5 times; urban population nearly doubled; adult literacy improved by nearly 30%; and life expectancy increased by more than 23% (about 15 years). However, this socioeconomic progress was accompanied by rapid rising environmental pressures. Between 1987 and 2015, water resource use increased four-fold, energy consumption increased approximately seven-fold, and large areas of natural grasslands were converted to agricultural, industrial, and urban land use. These impacts were exacerbated by large-scale coal production. To become more sustainable, Inner Mongolia’s development needs to better balance socioeconomic development and environmental protection, following a strong sustainability-oriented development model based on China’s new policy blueprint of “Ecological Civilization”. Towards this end, our study not only gauges the past unsustainable trajectory of Inner Mongolia, but also provides a scientific benchmark for promoting a more sustainable future for the region and beyond.",
        "keywords": "",
        "authors": [
            {
                "name": "Chenwei Shang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Tong Wu",
                "org": "School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA"
            },
            {
                "name": "Ganlin Huang",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            },
            {
                "name": "Jianguo Wu",
                "org": "Center for Human-Environment System Sustainability (CHESS), State Key Laboratory of Earth Surface Processes and Resource Ecology (ESPRE), Beijing Normal University, Beijing, 100875, China"
            }
        ],
        "venue": "Resources Conservation and Recycling",
        "year": 2019
    },
    "nzLiNbFh": {
        "id": "nzLiNbFh",
        "title": "Developmental Genetics of Valine Content at Different Grain Filling Stages in indica-japonica Hybrid Rice",
        "abstract": "Two developmental genetic models for quantitative traits of seeds in cereal crops, i.e. unconditional model referred to the analysis of cumulative measurements along the developmental stages, and conditional model referred to the gain analysis throughout the developmental stages, were used to analyse the developmental genetics of valine content at different grain filling stages in the indica-japonica hybrid rice. The valine content was governed by diploid maternal plant genes, triploid endosperm genes, cytoplasmic genes and their environmental interaction effects. Those genes were interval expressions among grain filling stages, and the most active stage when genes expressed was 8-14 days after flowering. Heritability analysis expressed that maternal heritability, cytoplasmic heritability and their environmental interactions were important at all the five filling stages. Single plant selection during early breeding generations would be effective to enhance the content of valine in rice breeding. Prediction of genetic effects in rice parents showed that Zhe 38A, Zhenong 8010A, Jin 23A, and Zhong 9308 could be used for improving the valine content in indica-japonica hybrids. The results also showed that Zhe 38A was more stable in different environmental conditions, it is the best one of the 12 parents tested for improving the valine content in rice breeding.",
        "keywords": [
            "rice quality",
            "hybrid rice",
            "developmental genetics",
            "indica-japonica hybrid",
            "valine",
            "grain filling",
            "heritability"
        ],
        "authors": [
            {
                "name": "ZHANG Xiao-ming",
                "org": "~ 1 College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China; ~ 2 Institute of Crop Research and Atomic Energy Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou , China"
            },
            {
                "name": "SHI Chun-hai",
                "org": "~ 1 College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "YE Sheng-hai",
                "org": " ~ 2 Institute of Crop Research and Atomic Energy Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou , China"
            },
            {
                "name": "WU Jian-guo",
                "org": "~ 1 College of Agriculture and Biotechnology, Zhejiang University, Hangzhou , China"
            },
            {
                "name": "BAO Gen-liang",
                "org": " ~ 2 Institute of Crop Research and Atomic Energy Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou , China"
            }
        ],
        "venue": "Chinese Journal of Rice Science",
        "year": 2006
    },
    "h36FQrrt": {
        "id": "h36FQrrt",
        "title": "Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2.",
        "abstract": "From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) crossed the species barriers to infect humans caused thousands of infections and hundreds of deaths, respectively. Currently, a novel coronavirus (SARS-CoV-2) causes the outbreaks of Coronavirus Disease 2019 (COVID-19) was discovered. Until February 18, 2020, there are 72533 confirmed COVID-19 cases (including 10644 severe cases) and 1872 deaths in China. SARS-CoV-2 is surging in the public and caused substantial burdens due to its human-to-human transmission. However, the intermediate host of SARS-CoV-2 is still unclear. Finding the possible intermediate host of SARS-CoV-2 is imperative to prevent further spread of the epidemic. In this study, we used systematic comparison and analysis to predict the interaction between the receptor binding domain (RBD) of coronavirus spike protein and the host receptor, Angiotensin Converting Enzyme 2 (ACE2). The interaction between the key amino acids of S protein RBD and ACE2 indicated that like previous suggested pangolins and snacks, the turtles (C. picta bellii, C. mydas, and P. sinensis) may act as the potential intermediate hosts transmitting SARS-CoV-2 to human. This article is protected by copyright. All rights reserved.",
        "keywords": [
            "Angiotensin Converting Enzyme 2 (ACE2)",
            "Coronavirus Disease 2019 (COVID-19)",
            "Receptor Binding Domain (RBD) of coronavirus",
            "SARS-CoV-2",
            "SARS-CoV-2 spike protein (S)"
        ],
        "authors": [
            {
                "name": "Zhixin Liu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Xiao Xiao",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Xiuli Wei",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jian Li",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jing Yang",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Huabing Tan",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Jianyong Zhu",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            },
            {
                "name": "Qiwei Zhang",
                "org": "School of Public Health, Southern Medical University, Guangzhou, 510515, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "State Key Laboratory of Virology and College of Life Sciences, Wuhan University, Wuhan, 430072, China."
            },
            {
                "name": "Long Liu",
                "org": "School of Basic Medical Sciences, Department of Respiratory, Department of Infectious Diseases, Renmin Hospital, Hubei University of Medicine, Shiyan, 442000, China."
            }
        ],
        "venue": "Journal of medical virology",
        "year": 2020
    },
    "m52l7Wox": {
        "id": "m52l7Wox",
        "title": "The impacts of climate change on the biodiversity:Vulnerability and Adaptation",
        "abstract": "The vulnerability and the adaptation for the impacts of climate change on biodiversity are directly related to conversation biodiversity in future.The concept of vulnerability and adaptation for the effects of climate change on biodiversity were interpreted.The study on the vulnerability and the impacts of climate change on biodiversity,and the adaptation of biodiversity to climate change by natural and artificial adjustments were reviewed.The uncertainness about the studies was also discussed,and the demands of re-search in future were suggested.The observation and investigation showed that climate change in past years has caused change in their phenlogy,distribution and abundance of many plants and animals,and cause extinction of some species,and also caused in-creasing of the frequency and intensity of outbreaks of some pest or disease,and cause expansion range of some exotic species,and cause change in the structure and function of some ecosystems.Climate change in future will still cause change in their phenology,distribution and abundance of many plants or animals,and will also cause habits loss of some species,and make increasing of the frequency and intensity outbreaks of some pests or diseases.Additionally,climate change in future will also make expansion range of some exotic species,and cause change in structure and function of some ecosystems.The adaptations of biodiversity to climate change include natural and artificial adjustments.The natural adjustments to climate change include the evolution response of species to climate change,migration of plants or animals,and the resilience and stabilization of ecosystems;the artificial adaptation to cli-mate change include the conservation genetic diversity of species,in situ or ex situ conservation of species,ecosystem management,restoration of degradation ecosystem,and reducing the climatic disaster following climate change.At present,there are still no enough studies of the vulnerability and adaptation about the impacts of climate change on the biodiversity,and the studies on the natural or artificial adaptation of biodiversity to climate change should be improved in future.",
        "keywords": [
            "biodiversity",
            "vulnerability",
            "impact",
            "climate change",
            "adaptation"
        ],
        "authors": [
            {
                "name": "Wu Jianguo",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing,,China"
            },
            {
                "name": "Lv Jiajia",
                "org": "Chinese Research Academy of Environmental Sciences,Beijing,,China"
            },
            {
                "name": "Ai Li",
                "org": "The Science and Technology University of Beijing,Beijing,,China"
            }
        ],
        "venue": "Ecology and Environmental Sciences",
        "year": 2009
    },
    "PtzoNDjK": {
        "id": "PtzoNDjK",
        "title": "Development of hull structure fatigue analysis system by hot spot stress method",
        "abstract": "The hot spot stress fatigue complex analysis of the hull structure is difficult to be implemented according to the guidelines for assessment of hull structure fatigue strength by CCS.A fatigue analysis system of hull structure is developed based on Patran Command Language of MSC.Patran to automatically achieve the deduction of corrosion allowance,load calculation,imposed fatigue loading,results extraction and analysis,which can greatly improve the efficiency of the hull structure fatigue analysis.",
        "keywords": [
            "hot spot stress",
            "Patran Command Language(PCL)",
            "hull structure",
            "fatigue analysis"
        ],
        "authors": [
            {
                "name": "SONG Ya-ling",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Architectural & Civil Engineering,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "LIN Yong",
                "org": "Ship Inspection Bureau of Zhejiang Province,Hangzhou ,China"
            }
        ],
        "venue": "Ship & Boat",
        "year": 2012
    },
    "eoSyeXF9": {
        "id": "eoSyeXF9",
        "title": "Design of Large Screen Interactive Display System of Multimedia",
        "abstract": "It designs a new large screen interactive multimedia display system,the system uses the back projection display technology,using computer vision and computer intelligent image recognition technology,realizes large screen projection virtual touch and remote gestures,which realizes the operation such as flipping pages on the left and right and click on the pages,the system is equipped with a multimedia production and display software,makes the contents convenient and flexible,through the text,picture,voice,flash,video and other forms display information.The viewer will be excited by the friendly interactions and novel mode of operation at the first time through the contents of the strong interest,its new operating mode can avoid the cross infection of diseases,the system can be widely used in the exhibition hall which has the nature of exhibition,guide of public places.",
        "keywords": [
            "multimedia",
            "large screen",
            "interaction",
            "intelligence recognition technology"
        ],
        "authors": [
            {
                "name": "LI Jian-xin",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education, Anhui University,Hefei ,China"
            },
            {
                "name": "GUO Xing",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education, Anhui University,Hefei ,China"
            },
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology,Anhui University,Hefei ,China;Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education, Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education, Anhui University,Hefei ,China;School of Software Engineering,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2012
    },
    "Er5wAByT": {
        "id": "Er5wAByT",
        "title": "Determination of Lead,Manganese,Iron and Phosphorus in Gasoline by Inductively Coupled Plasma Emission Spectroscopy",
        "abstract": "The lead,manganese,iron and phosphorus in the samples were treated with nitric acid after ashes at high temperature,and the amout of lead,manganese,iron and phosphorus were determined by Inductively coupled plasma emission spectroscopy.The linear relation of detection is in the range of 0—10μg/L for lead,manganese,iron and phosphorus,with the relative standard deviation of 1.68%—5.00%and the relative coefficient of 0.999.The recovery is 96.0%—104.9%.",
        "keywords": [
            "Gasoline",
            "Inductively Coupled Plasma Emission Spectroscopy",
            "Phosphorus",
            "Iron",
            "Manganese",
            "Lead"
        ],
        "authors": [
            {
                "name": "CHEN Xin-Yue",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "WU Jian-Guo",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "SUN Yan-Wei",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "YU Xiao-Zhan",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of liaoning,Dalian,Liaoning ,P.R.China"
            },
            {
                "name": "ZHANG Ying-Yan",
                "org": "Technology Centre of Entry-Exit Inspection and Quarantine Bureau of liaoning,Dalian,Liaoning ,P.R.China"
            }
        ],
        "venue": "Chinese Journal of Spectroscopy Laboratory",
        "year": 2009
    },
    "TOZg2h58": {
        "id": "TOZg2h58",
        "title": "The Application of Fuzzy-PID Control to Temperature Control of Nicotinic Acid Agitated Reactor",
        "abstract": "The temperature control of nicotinic acid agitated reactor has been discussed and designed in this paper.The constant change of the characteristics of agitated reactor in the chemical process causes difficulty in PID control.Therefore,by combination with the characteristics of the control system,the fuzzy-PID control is applied so as to make it possible for PID parameters to change automatically in a proper way.The result solves the problem in the production of nicotinic acid.",
        "keywords": [
            "agitated reactor",
            "nicotinic acid",
            "fuzzy control of temperature"
        ],
        "authors": [
            {
                "name": "MA Cong",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            },
            {
                "name": "ZHU Hai-rong",
                "org": "School of Electrical Engineering,Nantong University,Nantong ,China"
            }
        ],
        "venue": "Journal of Nantong University(Natural Science)",
        "year": 2006
    },
    "TgC4PNAQ": {
        "id": "TgC4PNAQ",
        "title": "Reliability analysis of response surface method baded on a double weighted regression technique",
        "abstract": "A response surface method is proposed for reliability analysis of implicit limit state equation,and the structural response is computed by the finite element method.Typically,the response surface method with an unknown coefficient polynomial instead of an implicit limit state function,which polynomial fitted by a number of sampling points,The locations of these points must be selected in a judicious way to reduce the computational time without deteriorating the quality of the polynomial approximation.To accelerate the iterative convergence speed,the authours propose some improvements,The response surface is fitted by the weighted regression technique,which allows the fitting points to be weighted according to their distance from the true failure surface and their distance from the estimated design point.This method aims to minimize computational time while producing satisfactory results.The efficiency and the accuracy of the proposed method can be evaluated by examples taken from the literature.",
        "keywords": [
            "response surface method",
            "weighted regression",
            "structural reliability",
            "limit state function"
        ],
        "authors": [
            {
                "name": "ZHONG Hong-lin",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": "College of Civil Engineering and Architecture,Zhejiang University of Technology,Hangzhou ,China"
            },
            {
                "name": "WANG Heng-jun",
                "org": "Zhejiang Prov Institute of Architectural Design and Rereach,Hangzhou ,China"
            }
        ],
        "venue": "Journal of Zhejiang University of Technology",
        "year": 2010
    },
    "elHHFiwK": {
        "id": "elHHFiwK",
        "title": "Spatial patterns of soil nutrients, plant diversity, and aboveground biomass in the Inner Mongolia grassland: before and after a biodiversity removal experiment",
        "abstract": "Spatial heterogeneity is ubiquitous in ecological systems, and has important effects on biological diversity and ecological processes.",
        "keywords": [
            "Biodiversity and Ecosystem Functioning (BEF)",
            " Removal experiments",
            " Spatial heterogeneity",
            " Pattern analysis",
            " Disturbance",
            " Inner Mongolia grassland"
        ],
        "authors": [
            {
                "name": "fei yuan",
                "org": "arizona state university"
            },
            {
                "name": "jianguo wu",
                "org": "arizona state university"
            },
            {
                "name": "ang li",
                "org": "chinese academy of sciences"
            },
            {
                "name": "helen rowe",
                "org": "arizona state university"
            },
            {
                "name": "yongfei bai",
                "org": "chinese academy of sciences"
            },
            {
                "name": "jianhui huang",
                "org": "chinese academy of sciences"
            },
            {
                "name": "xingguo han",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "Landscape Ecology",
        "year": 2015
    },
    "2rMzW8xI": {
        "id": "2rMzW8xI",
        "title": "Clinical Strategy of Improving the Success Rate of Femoral Hernia Surgery(A Report of 97 Cases)",
        "abstract": "Objective To study the diagnosis and surgery treatment of femoral hernia.Methods The clinical data of 97 cases of femoral hernia was retrospectively analyzed.All the patients were diagnosed by examining palpable lump in the femoral and imaging result,and underwent operation except in 1 case of death.87 cases were treated by inguinal ligament approach,1 case was treated by inguinal ligament approach,and 8 cases were treated by the exploratory incision of lower abdomen.68 cases(70.83%) were treated by McVay hernia repair,13 cases(13.54%) were treated by high ligation,14 cases(14.58%) were treated by Lichtenstein hernia repair,and 1 case(1.04%) was treated by femoral hernioplasty under inguinal ligament.All cases were given antibiotics after operation.Resultsin 96 patients,94 cases were cured with surgery,with 2 cases of death because of emergence of heart and lung failure after operation,and the total mortality was 3.09%;and 1 case relapsed one year after operation in 94 cases followed up for 6 months to 5 years.ConclusionThere is a high incidence of incarceration or strangulated for femoral hernia.Physical examination and ultrasonography are helpful for diagnosing femoral hernia.Early surgical treatment is an effective approach to reduce complications and mortality.",
        "keywords": [
            "McVay hernia repair",
            "cohort",
            "Hernia",
            "Surgical procedures",
            "Lichtenstein hernia repair"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Department of General Surgery,Changhai Hospital Affiliated to the Second Military Medical University of PLA,Shanghai ,China"
            },
            {
                "name": "NIE Ming-ming",
                "org": "Department of General Surgery,Changhai Hospital Affiliated to the Second Military Medical University of PLA,Shanghai ,China"
            },
            {
                "name": "XUE Xu-chao",
                "org": "Department of General Surgery,Changhai Hospital Affiliated to the Second Military Medical University of PLA,Shanghai ,China"
            },
            {
                "name": "BI Jian-wei",
                "org": "Department of General Surgery,Changhai Hospital Affiliated to the Second Military Medical University of PLA,Shanghai ,China"
            },
            {
                "name": "FANG Guo-en",
                "org": "Department of General Surgery,Changhai Hospital Affiliated to the Second Military Medical University of PLA,Shanghai ,China"
            }
        ],
        "venue": "Clinical Misdiagnosis & Mistherapy",
        "year": 2011
    },
    "z4JNIcgy": {
        "id": "z4JNIcgy",
        "title": "Study of the Automatic Control of Pellet Mill",
        "abstract": "Pellet mill,which usually consists of feeding unit,conditioning tank unit and pelleting unit,is one of the key equipments among feed machinery ones.Its conditioning tank belongs to multi-variable coupled objects, and usually it can only be hand operated with low productive efficiency.Double-input double-output mathematic model for pellet mill conditioning tank was established and decoupling by applying decoupling design was achieved.The pellet mill control system was designed.In order to strength the control effect,predictive functional control (PFC) was used and the effective control of pellet mills was obtained.Practical operation manifests that by this control method,the pellet mill can run at full capacity while palletizing normally.",
        "keywords": [
            "Predictive functional control",
            "Pellet mill",
            "Conditioning tank"
        ],
        "authors": [
            {
                "name": "ZHANG Peijian",
                "org": "School of Electrical Information,Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "WU Jianguo",
                "org": "School of Electrical Engineering,Nantong University,Nantong Jiangsu ,China"
            }
        ],
        "venue": "Machine Tool & Hydraulics",
        "year": 2008
    },
    "wUyPnFr2": {
        "id": "wUyPnFr2",
        "title": "Biogenesis, Function, and Applications of Virus-Derived Small RNAs in Plants.",
        "abstract": "RNA silencing, an evolutionarily conserved and sequence-specific gene-inactivation system, has a pivotal role in antiviral defense in most eukaryotic organisms. In plants, a class of exogenous small RNAs (sRNAs) originating from the infecting virus called virus-derived small interfering RNAs (vsiRNAs) are predominantly responsible for RNA silencing-mediated antiviral immunity. Nowadays, the process of vsiRNA formation and the role of vsiRNAs in plant viral defense have been revealed through deep sequencing of sRNAs and diverse genetic analysis. The biogenesis of vsiRNAs is analogous to that of endogenous sRNAs, which require diverse essential components including dicer-like (DCL), argonaute (AGO), and RNA-dependent RNA polymerase (RDR) proteins. vsiRNAs trigger antiviral defense through post-transcriptional gene silencing (PTGS) or transcriptional gene silencing (TGS) of viral RNA, and they hijack the host RNA silencing system to target complementary host transcripts. Additionally, several applications that take advantage of the current knowledge of vsiRNAs research are being used, such as breeding antiviral plants through genetic engineering technology, reconstructing of viral genomes, and surveying viral ecology and populations. Here, we will provide an overview of vsiRNA pathways, with a primary focus on the advances in vsiRNA biogenesis and function, and discuss their potential applications as well as the future challenges in vsiRNAs research.",
        "keywords": [
            "AGOs",
            "DCLs",
            "RDRs",
            "RNA silencing",
            "plant antiviral defense",
            "small RNAs",
            "virus-derived small RNAs"
        ],
        "authors": [
            {
                "name": "Chao Zhang",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University Fuzhou, China."
            },
            {
                "name": "Zujian Wu",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University Fuzhou, China."
            },
            {
                "name": "Yi Li",
                "org": "Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University Beijing, China."
            },
            {
                "name": "Jianguo Wu",
                "org": "Key Laboratory of Plant Virology of Fujian Province, Institute of Plant Virology, Fujian Agriculture and Forestry University Fuzhou, China ; Peking-Yale Joint Center for Plant Molecular Genetics and Agrobiotechnology, The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University Beijing, China."
            }
        ],
        "venue": "Frontiers in microbiology",
        "year": 2015
    },
    "MRhEMLt2": {
        "id": "MRhEMLt2",
        "title": "The QTL analysis on maternal and endosperm genome and their environmental interactions for characters of cooking quality in rice (Oryza sativa L.).",
        "abstract": "Investigations to identify quantitative trait loci (QTLs) governing cooking quality traits including amylose content, gel\n consistency and gelatinization temperature (expressed by the alkali spread value) were conducted using a set of 241 RIL populations\n derived from an elite hybrid cross of “Zhenshan 97” × “Minghui 63” and their reciprocal backcrosses BC1F1 and BC2F1 populations in two environments. QTLs and QTL × environment interactions were analyzed by using the genetic model with endosperm\n and maternal effects and environmental interaction effects on quantitative traits of seed in cereal crops. The results suggested\n that a total of seven QTLs were associated with cooking quality of rice, which were subsequently mapped to chromosomes 1,\n 4 and 6. Six of these QTLs were also found to have environmental interaction effects.",
        "keywords": [
            "quantitative trait",
            "interaction effect",
            "quantitative trait loci",
            "genetics",
            "maternal effect"
        ],
        "authors": [
            {
                "name": "X. Zheng",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "J. G. Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "X. Y. Lou",
                "org": "University of Virginia(University of Virginia),Charlottesville,United States"
            },
            {
                "name": "H. M. Xu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "C. H. Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik",
        "year": 2008
    },
    "gTFGjZHm": {
        "id": "gTFGjZHm",
        "title": "Characterization of an outbreak of hand, foot, and mouth disease in nanchang, china in 2010",
        "abstract": "Recent outbreaks of human enterovirus 71 (EV71) infection and EV71-associated hand, foot, and mouth disease (HFMD) in China have affected millions and potentially lead to life-threatening complications in newborns. Furthermore, these outbreaks represent a significant global public health issue in the world. Understanding the epidemiology of HFMD and EV71 infection and their transmission patterns in China is essential for controlling outbreaks. However, no studies on the outbreaks of HFMD and EV71 infection in China during 2010 have been reported. In this report, we carried out an epidemiological analysis to study an outbreak of HFMD and EV71 infection in 2010 in the city of Nanchang in the Jiangxi province of People's Republic of China. From April 7 to May 11, 2010, a total of 109 HFMD cases were reported, and in this report the HFMD cases were studied by both epidemiological and laboratory analyses. The epidemiological study indicates that children aged younger than 8 years old represented more than 90% of the reported cases, with the age group of 1-3 years containing the highest number of cases. Laboratory studies detected a high prevalence of EV71 amongst the cases in our study, suggesting EV71 as a common enterovirus found in HFMD cases in Nanchang. Phylogenetic analysis of the sequence of the VP1 region of four EV71 isolates indicated that the Nanchang strains belong to the C4 subgenotype commonly found in China during outbreaks in 2008 but contain distinct variations from these strains. Our study for the first time characterizes the epidemiology of HFMD and EV71 infection in China in 2010 and furthermore, provides the first direct evidence of the genotype of EV71 circulating in Nanchang, China. Our study should facilitate the development of public health measures for the control and prevention of HFMD and EV71 infection in at-risk individuals in China. © 2011 Liu et al.",
        "keywords": [
            "public health",
            "age groups"
        ],
        "authors": [
            {
                "name": "Michelle Y. Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Weiyong Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Jun Luo",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yingle Liu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            },
            {
                "name": "Yang Zhu",
                "org": "Relia Biotechnologies(Jiangsu), Inc(Relia Biotechnologies(Jiangsu), Inc,Jiangsu Affynigen Biotechnologies, Inc.,Jiangsu Affynigen Biotechnologies, Inc),,China"
            },
            {
                "name": "Hillary Berman",
                "org": "UC Berkeley(University of California),Berkeley,United States"
            },
            {
                "name": "Jianguo Wu",
                "org": "Wuhan University(Wuhan University),Wuhan,China"
            }
        ],
        "venue": "PLoS ONE",
        "year": 2011
    },
    "AmrF9awc": {
        "id": "AmrF9awc",
        "title": "The daily rhythms of mitochondrial gene expression and oxidative stress regulation are altered by aging in the mouse liver.",
        "abstract": "The circadian clock regulates many cellular processes, notably including the cell cycle, metabolism and aging. Mitochondria play essential roles in metabolism and are the major sites of reactive oxygen species (ROS) production in the cell. The clock regulates mitochondrial functions by driving daily changes in NAD(+) levels and Sirt3 activity. In addition to this central route, in the present study, we find that the expression of some mitochondrial genes is also rhythmic in the liver, and that there rhythms are disrupted by the Clock(Δ19) mutation in young mice, suggesting that they are regulated by the core circadian oscillator. Related to this observation, we also find that the regulation of oxidative stress is rhythmic in the liver. Since mitochondria and ROS play important roles in aging, and mitochondrial functions are also disturbed by aging, these related observations prompt the compelling hypothesis that circadian oscillators influence aging by regulating ROS in mitochondria. During aging, the expression rhythms of some mitochondrial genes were altered in the liver and the temporal regulation over the dynamics of mitochondrial oxidative stress was disrupted. However, the expression of clock genes was not affected. Our results suggested that mitochondrial functions are combinatorially regulated by the clock and other age-dependent mechanism(s), and that aging disrupts mitochondrial rhythms through mechanisms downstream of the clock.",
        "keywords": [
            "Aging",
            "circadian rhythms",
            "mitochondria",
            "oxidative stress"
        ],
        "authors": [
            {
                "name": "Changxia Gong",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            },
            {
                "name": "Chengwei Li",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            },
            {
                "name": "Xiaoqing Qi",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            },
            {
                "name": "Zhiyin Song",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            },
            {
                "name": "Jianguo Wu",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            },
            {
                "name": "Michael E Hughes",
                "org": "b Department of Biology , University of Missouri-St. Louis . St. Louis, MO , USA."
            },
            {
                "name": "Xiaodong Li",
                "org": "a State Key Laboratory of Virology, College of Life Sciences, Wuhan University , Wuhan, Hubei Province , P.R. China and."
            }
        ],
        "venue": "Chronobiology international",
        "year": 2015
    },
    "JwTOuDS4": {
        "id": "JwTOuDS4",
        "title": "Quantifying Surface Coal-Mining Patterns to Promote Regional Sustainability in Ordos, Inner Mongolia",
        "abstract": "Ordos became the new “coal capital” of China within a few decades since the country’s economic reform in 1978, as large-scale surface coal mining dramatically propelled its per capita GDP from being one of the lowest to one of the highest in China, exceeding Hong Kong in 2009. Surface coal-mining areas (SCMAs) have continued to expand in this region during recent decades, resulting in serious environmental and socioeconomic consequences. To understand these impacts and promote regional sustainability, quantifying the spatiotemporal patterns of SCMAs is urgently needed. Thus, the main objectives of this study were to quantify the spatiotemporal patterns of SCMAs in the Ordos region from 1990 to 2015, and to examine some of the major environmental and socioeconomic impacts in the study region. We extracted the SCMAs using remote-sensing data, and then quantified their spatiotemporal patterns using landscape metrics. The loss of natural habitat and several socioeconomic indicators were examined in relation to surface coal mining. Our results show that the area of SCMAs increased from 7.12 km2 to 355.95 km2, an increase of nearly 49 times from 1990 to 2015 in the Ordos region. The number of SCMAs in this region increased from 82 to 651, a nearly seven-fold increase. In particular, Zhungeer banner (an administrative division), Yijinhuoluo banner, Dongsheng District and Dalate banner in the north-eastern part of the Ordos region had higher growth rates of SCMAs. The income gap between urban and rural residents increased along with the growth in SCMAs, undermining social equity in the Ordos region. Moreover, the rapid increase in SCMAs resulted in natural habitat loss (including grasslands, forests, and deserts) across this region. Thus, we suggest that regional sustainability in Ordos needs to emphasize effective measures to curb large-scale surface coal mining in order to reduce the urban–rural income gap, and to restore degraded natural ecosystems.",
        "keywords": "",
        "authors": [
            {
                "name": "Xiaoji Zeng",
                "org": "Beijing Normal University"
            },
            {
                "name": "Zhifeng Liu",
                "org": "Beijing Normal University"
            },
            {
                "name": "Chunyang He",
                "org": "Beijing Normal University"
            },
            {
                "name": "Qun Ma",
                "org": "Beijing Normal University"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            },
            {
                "name": "Jianguo Wu",
                "org": "Sustainability, Julie Ann Wrigley Global Institute of (GIOS)"
            }
        ],
        "venue": "Sustainability",
        "year": 2018
    },
    "XwVKvWrz": {
        "id": "XwVKvWrz",
        "title": "On species occupancy-abundance models",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Fangliang He",
                "org": "Canadian Forest Service, Pacific Forestry Centre, 506 West Burnside Road, Victoria, British Columbia, V8Z 1M5, Canada Email: fhe@pfc.forestry.ca"
            },
            {
                "name": "Kevin J. Gaston",
                "org": "Biodiversity and Macroecology Group, Department of Animal and Plant Sciences, University of Sheffield, Sheffield, S10 2TN, United Kingdom"
            },
            {
                "name": "Jianguo Wu",
                "org": "Department of Plant Biology, Arizona State University, P.O. Box 871601, Tempe, Arizona, 85287-1601, U.S.A."
            }
        ],
        "venue": "Ecoscience",
        "year": 2002
    },
    "I13fUPCf": {
        "id": "I13fUPCf",
        "title": "HIV and HCV: from Co-infection to epidemiology, transmission, pathogenesis, and treatment",
        "abstract": "Human immunodeficiency virus (HIV) is the infectious agent causing acquired immunodeficiency syndrome (AIDS), a deadliest\n scourge of human society. Hepatitis C virus (HCV) is a major causative agent of chronic liver disease and infects an estimated\n 170 million people worldwide, resulting in a serious public health burden. Due to shared routes of transmission, co-infection\n with HIV and HCV has become common among individuals who had high risks of blood exposures. Among hemophiliacs the co-infection\n rate accounts for 85%; while among injection drug users (IDU) the rate can be as high as 90%. HIV can accelerate the progression\n of HCV-related liver disease, particularly when immunodeficiency has developed. Although the effect of HCV on HIV infection\n is controversial, most studies showed an increase in mortality due to liver disease. HCV may act as a direct cofactor to fasten\n the progression of AIDS and decrease the tolerance of highly active antiretroviral therapy (HARRT). Conversely, HAART-related\n hepatotoxicity may enhance the progression of liver fibrosis. Due to above complications, co-infection with HCV and HIV-1\n has imposed a critical challenge in the management of these patients. In this review, we focus on the epidemiology and transmission\n of HIV and HCV, the impact of the two viruses on each other, and their treatment.",
        "keywords": [
            "acquired immunodeficiency syndrome aids",
            "co-infection",
            "epidemiology",
            "hepatitis c virus (hcv)",
            "acquired immunodeficiency syndrome (aids)",
            "hepatitis c virus hcv",
            "human immunodeficiency virus (hiv)",
            "human immunodeficiency virus hiv",
            "Acquired immunodeficiency syndrome (AIDS)",
            "Human immunodeficiency virus (HIV)",
            "Hepatitis C virus (HCV)",
            "Epidemiology",
            "Co-infection",
            "R511"
        ],
        "authors": [
            {
                "name": "Lei Kang",
                "org": "Wuhan University The State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 China"
            },
            {
                "name": "Jing Hu",
                "org": "Wuhan University The State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 China"
            },
            {
                "name": "Xue-shan Xia",
                "org": "Kunming University of Science and Technology College of Life Sciences Kunming 650224 China"
            },
            {
                "name": "Jian-guo Wu",
                "org": "Wuhan University The State Key Laboratory of Virology, College of Life Sciences Wuhan 430072 China"
            }
        ],
        "venue": "Virologica Sinica",
        "year": 2007
    },
    "lxfcpYRP": {
        "id": "lxfcpYRP",
        "title": "An Alternative Intraoperative Radiographic Method for Optimizing Cup Inclination during Total Hip Arthroplasty.",
        "abstract": "During total hip arthroplasty (THA), the location of the acetabular prosthesis is very important for guaranteeing successful surgery. However, this remains a challenge for many surgeons. This study aimed to investigate the feasibility of using the intraoperative fluoroscopic iliopubic tangential angle (IPTA) to determine the valgus angles of acetabular prostheses.In the first stage, the IPTA and valgus angles of native acetabula were defined and measured in 102 THAs obtained from the picture archiving and communication systems of our hospital. Obturator foramen morphology was also measured and divided into groups according to the axial length ratio. Correlations between obturator foramen morphology and IPTA and valgus angles of native acetabula were then determined. In the second stage, angular differences (angle θ) between the IPTA and valgus angles of native acetabula were measured during unilateral THA in 136 patients to determine whether this is a stable value that could be used as a reference for placement of acetabular prostheses. Postoperative data such as Harris Hip Score (HHS) scores and complications were collected and evaluated.The average IPTA at the apex of the true acetabulum was 58.8° ± 4.1°. The average valgus angle of native acetabula was 43.1° ± 3.9° and angle θ was 15.7° ± 1.3°. Obturator foramen morphology was divided into five groups according to the axial length ratio. IPTA was closely related to obturator foramen morphology (Pearson r = 0.489, P ≈ 0.000). Angle θ was stable and independent of obturator foramen morphology. When the IPTA and angle θ were used as references for placing acetabular prostheses in 136 THAs, the average postoperative valgus angles of acetabular prostheses was 45.13° ± 4.07° and the good-to-excellent rate was 97.05%. There were no short-term complications such as fracture, dislocation or infection. The average HHS score 6 months after surgery was 37.2 higher than the preoperative score, this difference being significant (P < 0.01). Neither infection nor dislocation was found 6 months after surgery.The IPTA (at the apex of the true acetabulum) and angle θ (obtained by intraoperative fluoroscopy) are consistent in determining the postoperative valgus angle of acetabular prosthesis during THA. Thus, IPTA and angle θ are of value in guiding placement of acetabular prostheses; in particular, this method can facilitate the learning of young surgeons.",
        "keywords": [
            "Cup inclination",
            "Iliopubic tangential angle",
            "Radiographic method",
            "Total hip arthroplasty"
        ],
        "authors": [
            {
                "name": "Gang-Yong Huang",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Guang-Lei Zhao",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Jun Xia",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China. dr.xiajun@139.com."
            },
            {
                "name": "Yi-Bing Wei",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Si-Qun Wang",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China."
            },
            {
                "name": "Jian-Guo Wu",
                "org": "Division of Orthopaedic Surgery, Huashan Hospital, Fudan University, Shanghai, China."
            }
        ],
        "venue": "Orthopaedic surgery",
        "year": 2016
    },
    "fXJ55XhZ": {
        "id": "fXJ55XhZ",
        "title": "On Promoting the Development of the Professional Education Cored by Constructing the System of Modern Professional Education",
        "abstract": "This paper discusses the relation between the system of modern professional education and the adjustment of industrial structure.It proposes the cultivation of more skilled talents and more high-qualified high-skilled talents as constructing the system of modern higher professional education in order to promote the development of professional education.Through constructing the system of modern professional education and in accordance with the request for the local modernization,the support of the talents and intelligence in the system of the modern professional education for economic and social development is necessary.It also focuses on the combination of secondary and higher professional education,proposes the construction of the system of modern occupation education as the core,and advances the several main measures to develop the professional education in Shazhou Professional Institute of Technology.",
        "keywords": [
            "Combination of Secondary and higher professional education",
            "Skilled talents",
            "adjustment of industrial structure",
            "The system of modern professional education"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "YI Shun-ming",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            },
            {
                "name": "CHEN Zai-tie",
                "org": "Shazhou Professional Institute of Technology,Zhangjiagang ,China"
            }
        ],
        "venue": "Journal of Shazhou Professional Institute of Technology",
        "year": 2013
    },
    "MeaHlMpq": {
        "id": "MeaHlMpq",
        "title": "Genre Analysis of the User's Manual from the Perspective of Game-Theoretical Pragmatics",
        "abstract": "As an important approach to pragmatics,game-theoretical pragmatics is of great methodological significance since it studies the generation and interpretation of language communication by developing a game-theoretical model.This paper discusses its application to genre analysis of the user's manual.Firstly,it discloses the family resemblance attributes of instructional genre,and thereby builds up the cognitive model of the user's manual.Then,it explores the cognitive-inferential mechanism of the user's manual within the framework of game-theoretical pragmatics.By constructing a metagame and introducing rational person hypothesis,it accounts for the generative mechanism of the user's manual,with a special focus on its motivation.Finally,it illustrates the conversational implicature in the user's manual by applying Parikh's game model of communication.",
        "keywords": [
            "game-theoretical pragmatics",
            "user's manual",
            "genre analysis"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,Guangdong "
            },
            {
                "name": "XU Ying",
                "org": "School of Foreign Languages,South China University of Technology,Guangzhou,Guangdong "
            }
        ],
        "venue": "Journal of Shenzhen University(Humanities & Social Sciences)",
        "year": 2012
    },
    "65PVnvoe": {
        "id": "65PVnvoe",
        "title": "General Spatiotemporal Patterns of Urbanization: An Examination of 16 World Cities",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "zhifeng liu",
                "org": ""
            },
            {
                "name": "chunyang he",
                "org": ""
            },
            {
                "name": "jianguo wu",
                "org": ""
            }
        ],
        "venue": "Sustainability",
        "year": 2016
    },
    "WYMWB9QU": {
        "id": "WYMWB9QU",
        "title": "Virtual touch screen system based on one-dimensional image recognition",
        "abstract": "This paper designs a virtual touch screen which is composed of one-dimensional image acquisition equipments,screen and data processing settings.It avoids finger recognition problem due to body shade in large size screen.Points in one dimensional coordinate are converted to point in two-dimensional virtual touch screen by data processing settings according to corresponding relation between one-dimension coordinate in one-dimensional image and two-dimension coordinate in virtual touch screen.One-dimensional image acquisition equipment adopts one -dimensional linearity sensor,lens,signal conversion and interface circuit.It can also adopt camera obtained from market easily,but only use one row or one list data in two-dimensional image.",
        "keywords": [
            "camera",
            "one-dimensional image acquisition equipment",
            "image recognition",
            "finger location",
            "virtual touch screen"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": ".1.School of Computer Science and Technology,Anhui University,Hefei ,China 2.Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China 3.School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "WU Jian-guo",
                "org": ".1.School of Computer Science and Technology,Anhui University,Hefei ,China 2.Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China 3.School of Software Engineering,Anhui University,Hefei ,China"
            },
            {
                "name": "LI Wei",
                "org": ".1.School of Computer Science and Technology,Anhui University,Hefei ,China 2.Key Laboratory of Intelligent Computing & Signal Processing of Ministry of Education,Anhui University,Hefei ,China 3.School of Software Engineering,Anhui University,Hefei ,China"
            }
        ],
        "venue": "Computer Engineering and Applications",
        "year": 2010
    },
    "MgEukPP5": {
        "id": "MgEukPP5",
        "title": "Chinese word segment based on alternative covering algorithm",
        "abstract": "Chinese word segment is very important in natural language processing.Chinese word segment is regards as classified process of character.The character is put in the linguistic environment which covers four characters around it.Every character belongs to one of such four categories as independent existence, existence connecting with the character before, existence connecting with the character after and existence connecting with the character before and after.The category of every character is judged by using alternative covering algorithm which has good classification effect.This method carries on statistics in a large annotated corpus and does not need the dictionary.It has a good solution to overlapping ambiguity and achieves 90.6% accuracy.",
        "keywords": [
            "alternative covering algorithm",
            "cover",
            "overlapping ambiguity",
            "mutual information",
            "Chinese word segment"
        ],
        "authors": [
            {
                "name": "LIU Zheng-yi",
                "org": "School of Computer Science and Technology, Anhui University, Hefei , China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, Anhui University, Hefei , China"
            },
            {
                "name": "WU Jian-guo",
                "org": "School of Computer Science and Technology, Anhui University, Hefei , China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, Anhui University, Hefei , China"
            },
            {
                "name": "LI Wei",
                "org": "School of Computer Science and Technology, Anhui University, Hefei , China;Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, Anhui University, Hefei , China"
            }
        ],
        "venue": "Computer Engineering and Design",
        "year": 2010
    },
    "MafV1zO9": {
        "id": "MafV1zO9",
        "title": "Research on the Model of Economic Effect Based on the Difference in District of FDI",
        "abstract": "This text establishes a logarithm model according to the theory analysis on economy increase and the spillage effect of FDI,and then researches on the relations between FDI and the development of economic difference in district with the horizontal and time data,and draws a conclusion that the influence that FDI imposes on the increase in GDP in the three regions has remarkable difference,and the influence in the eastern region is stronger than the western region and the central region.",
        "keywords": [
            "economic difference in district",
            "regression model"
        ],
        "authors": [
            {
                "name": "WU Jian-guo",
                "org": "Hunan College of Finance and Economics,Changsha Hunan ,China"
            },
            {
                "name": "AI Yan-lin",
                "org": "Hunan College of Finance and Economics,Changsha Hunan ,China"
            }
        ],
        "venue": "Journal of Hebei Polytechnic University(Social Science Edition)",
        "year": 2006
    },
    "QmeKoKbd": {
        "id": "QmeKoKbd",
        "title": "Thinking on causes and tactics to the vulnerability of public environment",
        "abstract": "Public environment features in vulnerability and the attribute of resource.The damage to public environment can not only bring about losses of social economy and property,but also increase the risk of endangering the public and public environmental security.Now China is undergoing rapid economic growth and social transformation,and the vulnerability of public environment is striking owning to the causes from many ways.To solve these problems,we must improve the public's knowledge,use rationally the public environment resources,and strengthen city planning and urban resources protection,etc..",
        "keywords": [
            "public environment",
            "vulnerability",
            "tactics",
            "causes",
            "attribute of resource"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "JIAO Feng",
                "org": ""
            }
        ],
        "venue": "Urban Problems",
        "year": 2006
    },
    "Q9LjJlbQ": {
        "id": "Q9LjJlbQ",
        "title": "Solid-diffusion, die-to-heat spreader bonding methods, articles achieved thereby, and apparatus used therefor",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "edward r hurley",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "Z6XqDIpV": {
        "id": "Z6XqDIpV",
        "title": "Understanding electronic and optical properties of La and Mn co-doped anatase TiO2",
        "abstract": "Abstract   The electronic structures, dipole moment, and optical properties of La-doped, Mn-doped, and La-Mn-doped anatase TiO 2  have been investigated by means of GGA + U first-principles method, showing that the absorption coefficients of the La-Mn-doped TiO 2  under visible light to be sensitive to the doping positions of La and Mn atoms. La-Mn-TiO 2 (1) exhibits the largest absorption coefficient in visible light because of the smallest band gap. Additionally, for the La and Mn co-doped TiO 2 , the large dipole moment of TiO 6  octahedron is in prejudice of enhancing the optical responses under the visible light. We successfully probe the interesting optical response mechanism in this work.",
        "keywords": "",
        "authors": [
            {
                "name": "Renhui Zhang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Juan Zhao",
                "org": "School of Mathematics and Information Science, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Yingchang Yang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Zhibin Lu",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            }
        ],
        "venue": "Computational Condensed Matter",
        "year": 2016
    },
    "hB0mOd8J": {
        "id": "hB0mOd8J",
        "title": "Dielectric relaxation of poled polymer DCNP/PMMA",
        "abstract": "We have prepared the polymer thin films of a 3-(1,1-dicyanothenyl)-1-phenyl-4,5-dihydro-1 H -pyrazole (DCNP)/poly (methyl methacrylate) (PMMA) guest–host system by spin coating. In order to investigate their temporal and temperature stability, we have measured their dielectric relaxation spectra including the frequency dependence of the real and imaginary parts of dielectric constants. The investigated frequency ranged from 50 Hz to 10 MHz. The measured temperature range above the glass transition temperature T g (95°C) of the DCNP/PMMA system was from 95°C to 125°C. By using the Adam–Gibbs model, the temperature dependence of the characteristic time τ above T g was fitted, and the values of the characteristic times τ below T g were estimated. The lifetimes of the polymer were evaluated by the Kohlrausch–Williams–Watts (KWW) empirical decay model.",
        "keywords": [
            "nonlinear optical material",
            "lifetime",
            "dielectric relaxation",
            "poled polymer",
            "characteristic time",
            "dielectric constant",
            "glass transition temperature",
            "thin film"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Xun Sun",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors, Chinese Academy Sciences, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Reactive and Functional Polymers",
        "year": 2000
    },
    "lHpywhoa": {
        "id": "lHpywhoa",
        "title": "Comparison of five equations to estimate glomerular filtration rate in patients with benign arteriolar nephrosclerosis.",
        "abstract": "Objectives To compare the applicability of five equations [Cockcroft-Gault(CG) adjusted for body surface area,original modification of diet in renal disease(MDRD),American abbreviated MDRD,Chinese modified MDRD and Chinese abbreviated MDRD) to estimate glomerular filtration rate(GFR) in patients with benign arteriolar nephrosclerosis.Methods Totally 140 patients diagnosed with benign arteriolar nephrosclerosis in Guangdong General Hospital from February 2010 to November 2011 were enrolled in this study.Plasma clearance measured by dual plasma sampling 99mTc-DTPA method was taken as a reference GFR.GFRs estimated by the five equations were compared to the reference GFR.Results Reference GFR measured by dual plasma sampling 99mTc-DTPA method was(39.3 ± 22.3) mL.min-1.1.73 m-2.CG adjusted for body surface area,original MDRD,American abbreviated MDRD equations underestimated the reference GFR(-6.90,-3.48,-2.59 mL.min-1.1.73 m-2,respectively).Chinese modified MDRD and Chinese abbreviated MDRD equations overestimated the reference GFR(4.07,5.96 mL.min-1.1.73 m-2,respectively).Compared with the other equations,the deviation of original MDRD equation(363.16,arbitrary units) was much smaller(CG adjusted for body surface area 876.24,American abbreviated MDRD 1 267.12,Chinese modified MDRD 483.82,Chinese abbreviated MDRD 1 516.90,arbitrary units).The precision and 30% accuracy of original MDRD equation was significantly higher than those of Chiense modified MDRD and Chinese abbreviated MDRD equations(P<0.05).Conclusions No equations mentioned above shows satisfactory performance for estimating GFR in patients with benign arteriolar nephrosclerosis.Compared with the other equations,the original MDRD equation may be more suitable to be used in patients with benign arteriolar nephrosclerosis for estimating GFR.",
        "keywords": [
            "glomerular filtration rate",
            "equation",
            "benign arteriolar",
            "nephrosclerosis"
        ],
        "authors": [
            {
                "name": "XIE Zhi-bin",
                "org": "Southern Medical University,Guangzhou ,China;Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "WANG Wen-jian",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "YE Zhi-ming",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "ZHANG Bin",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "MA Jian-chao",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "XU Li-xia",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            },
            {
                "name": "XU Wei-ping",
                "org": "Department of Urology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China"
            }
        ],
        "venue": "South China Journal of Cardiovascular Diseases",
        "year": 2013
    },
    "rN3R450j": {
        "id": "rN3R450j",
        "title": "Beta-blockers plus isosorbide-5-mononitrate for prevention of esophageal variceal rebleeding: a systematic review]",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xiao-Bin Sun",
                "org": "Department of Gastroenterology, Third People's Hospital of Chengdu, Chengdu 610031, China."
            },
            {
                "name": "Qiong Wang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology",
        "year": 2008
    },
    "cbjeqmp9": {
        "id": "cbjeqmp9",
        "title": "A New Method for Implementing All-purpose Remote Controller",
        "abstract": "Connecting with the pulse width measuring technique and the infrared decoding technology, this paper advances a new method for implementing all-purpose remote controller with a 51 single-chip computer. This method, decoding the infrared signal based on the analysis and classification of the different encoding formats and the measurement of the low and high power level duration, realizes learning and reshaping the infrared remote control signal of the different encoding formats with a unified approach, which, to a great extent, reduces the data quantity needing to save.",
        "keywords": [
            "all-purposel remote controller",
            "infrared signal decoding",
            "51 single-chip computer"
        ],
        "authors": [
            {
                "name": "REN Deng-feng",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2008
    },
    "Xb5dhvMD": {
        "id": "Xb5dhvMD",
        "title": "Reproductive biology and variation of nuclear ribosomal ITS and ETS sequences in the Calligonum mongolicum complex (Polygonaceae).",
        "abstract": "To explore the biosystematics of the  complex (Polygonaceae), the flowering phenological period, breeding and pollination characters and seed set of the complex ( Turze,  A. Los.,  A. Los.,  A. Los. and  A. Los.) were documented in the Turpan Eremophyte Botanical Garden, China. The sequences of the nuclear ribosomal ITS and ETS region were employed to differentiate the  complex and other species in sect. Medusae. The results showed species of the  complex occupied overlapping flowering periods and had consistent pollination agents. Their breeding systems are all self-compatible, tend to be out-crossing and they interbreed amongst each other (out-crossing index, OCI = 4).The crosses within and amongst species had high seed sets (44 - 65%). Phylogenetic analyses of Calligonum sect. Medusae and the network analysis of nrDNA (ITS and ETS) in the complex suggest interbreeding amongst \"species\" within the complex and provide evidence for taxonomically merging the five species in the complex. The detected hybridisation, occurring within the complex, suggests the need to improve traditional methods of  plant conservation in botanical gardens for maintaining genetic diversity of  within and amongst species from different geographic areas.",
        "keywords": [
            "Breeding System",
            "Calligonum mongolicum complex",
            "Crossing experiments",
            "ETS",
            "ITS",
            "Phenology",
            "Phylogeny"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanic Garden, Chinese Academy of Sciences, Turpan 838008, China."
            },
            {
                "name": "Jun Wen",
                "org": "Department of Botany, Smithsonian Institution, PO Box 37012, Washington, DC 20013-7012, USA."
            },
            {
                "name": "Yanfeng Zhao",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanic Garden, Chinese Academy of Sciences, Turpan 838008, China."
            },
            {
                "name": "Gabriel Johnson",
                "org": "Department of Botany, Smithsonian Institution, PO Box 37012, Washington, DC 20013-7012, USA."
            },
            {
                "name": "Borong Pan",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, China; Turpan Eremophytes Botanic Garden, Chinese Academy of Sciences, Turpan 838008, China."
            }
        ],
        "venue": "PhytoKeys",
        "year": 2017
    },
    "56DTLwkM": {
        "id": "56DTLwkM",
        "title": "One-pot solvothermal synthesis of ternary Ni-Co-P micro/nano-structured materials for high performance aqueous asymmetric supercapacitors",
        "abstract": "Abstract   The ternary Ni-Co-P micro/nano-structured materials were synthesized via a facile one-pot solvothermal strategy and further served as positive electrode materials for supercapacitors. X-ray diffraction (XRD) showed that the optimal Ni 8 -Co 1 -P materials exhibited the two major phases of M 12 P 5  and M 2 P (M = Ni, Co). X-ray photoelectron spectroscopy (XPS) revealed the binding energy shifts of P2p, Ni2p and Co2p of Ni 8 -Co 1 -P materials compared with the bare Ni-P and Co-P, indicating the formation of ternary materials. Transmission electron microscopy (TEM) and energy dispersive spectrometer (EDS) mapping exhibited the micro/nano-structured morphology with rich surface nanowires (5–10 nm in diameter) and the consistent distribution of Ni, Co and P elements of the Ni 8 -Co 1 -P materials respectively. Nitrogen sorption measurements illustrated the mesoporous structure of the Ni 8 -Co 1 -P materials with the specific surface area of 257 m 2  g −1 . Due to the richer Ni, Co surface electroactive sites and the stronger synergistic effect of Ni and Co redox species, the Ni 8 -Co 1 -P materials showed superior specific capacitance, rate capability and charge transfer kinetics (1448 F g −1  at 1 A g −1 , 1173 F g −1  at 16 A g −1 , 333 Ω) than the Ni-Co-P with other Ni/Co ratios (1:0, 16:1, 4:1, 2:1, 0:1). The mass ratio optimized activated carbon (AC)//Ni 8 -Co 1 -P asymmetric capacitor ( m +/ m − = 1:2) exhibited high energy and power densities (22.8 Wh kg −1 , 4.32 kW kg −1 ) together with excellent cycle life (no decay after 5000 cycles at 4 A g −1 ). The high performance makes the ternary Ni-Co-P micro/nano-structured materials promising electrode materials for supercapacitors.",
        "keywords": "",
        "authors": [
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            }
        ],
        "venue": "Chemical Engineering Journal",
        "year": 2017
    },
    "njT5jOlh": {
        "id": "njT5jOlh",
        "title": "Discussion on diagnosis and treatment of bleeding after placing intrauterine device",
        "abstract": "Placing intrauterine device(IUD) is one of the primary contraception for women in the child-bearing age,while bleeding after IUD placement is the main side effect.According to the TCM definition of the disease,the etiology,pathogenesis,diagnosis and treatment were summed up.The TCM study trend for the disease was demonstrated.",
        "keywords": [
            "blood stasis",
            "diagnosis and treatment",
            "deficiency of both Qi and blood",
            "bleeding after placing intrauterine device"
        ],
        "authors": [
            {
                "name": "LIU Rui-fen",
                "org": "Affliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Affliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "CHEN Lei",
                "org": "Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "XU Li",
                "org": "Licheng Hospital of Traditional Chinese Medicine,Jinan ,China"
            }
        ],
        "venue": "Shandong Journal of Traditional Chinese Medicine",
        "year": 2008
    },
    "ZWdukPER": {
        "id": "ZWdukPER",
        "title": "The complete mitochondrial genome sequence of Photopectoralis bindus (Perciformes: Leiognathidae)",
        "abstract": "AbstractThe complete mitochondrial genome of Photopectoralis bindus was sequenced by high throughput sequencing method in this study. Length of this genome is 16,517 bp, containing 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. ND6 and eight tRNA genes are encoded by L-strand, and others are encoded by H-strand, which is similar to those in most vertebrates. The nucleotide composition of the whole mitogenome is 29.9% A, 30.1% C, 15.1% G, and 25.0% T, with a slight bias of A + T content (54.9%). Phylogenetic tree based on the first and second codon sequences of 12 protein coding genes (except ND6) shows that the clade of P. bindus is closely clustered with that of Gazza minuta, and families Rachycentridae and Carangidae have the closest relationship to Leiognathidae.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, PR China; "
            },
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, PR China; "
            },
            {
                "name": "Baosheng Wu",
                "org": " CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, PR China"
            },
            {
                "name": "Hui Yu",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, PR China; "
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "7AJWfeLm": {
        "id": "7AJWfeLm",
        "title": "Parametric Study of Drivetrain Dynamics of a Wind Turbine Using the Multibody Dynamics",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Dezhi Ning",
                "org": ""
            },
            {
                "name": "Zhe Ma",
                "org": ""
            },
            {
                "name": "Nianxin Ren",
                "org": ""
            },
            {
                "name": "Hyunchul Park",
                "org": ""
            }
        ],
        "venue": "International Journal of Mechanical Engineering and Applications",
        "year": 2019
    },
    "pvbrMyrt": {
        "id": "pvbrMyrt",
        "title": "Late paleozoic crustal growth and tectonic evolution in Balkhash metallogenic belt (Kazakhstan), Central Asia",
        "abstract": "The Balkhash metallogenic belt in Kazakhstan is a famous porphyritic Cu-Mo metallogenic belt in the Central Asian metallogenic domain. The Late Paleozoic granitoids from Balkhash metallogenic belt are mainly of high-K calc-alkaline and I-type granites, with shoshonite in the late stage. Geochemistry analyses and tectonic discrimination show a change of tectonic setting from syn-collision and volcanic arc in Carboniferous to post-collision in Permian. The Late Paleozoic granitoids from Borly porphyry deposit formed in classical island-arc environment, though that from Kounrad, Aktogai and Sayak are adakitic. The εNd(t) values for the Late Paleozoic granitoids here are between -5. 87 and +5. 94, and εSr(t) values from - 17. 16 to +51.10. The continental crustal growth histories are different on the both sides of Central Balkhash fault. On the east side, εNd(t) values from Aktogai and Sayak are very high with character of depleted mantle, suggesting the crustal growth in the Late Paleozoic. On the west side, ε Nd(t) values from Borly and Kounrad are slightly low, suggesting the existence of the New Proterozoic basement and the mixing of crust and mantle during magmatism. The granitoids have 206Pb/204 Pb, 207Pb/204 Pb, and 208Pb/204 Pb values ranging in 18. 3346 ∼20. 9929, 15. 5213 ∼ 15. 7321 and 38. 2874 ∼40. 0209, respectively, showing the affinity of the Late Paleozoic magmatism in Balkhash with that in Tianshan, Altai and Junggar areas.",
        "keywords": [
            "Balkhash metallogenic belt",
            "Crustal growth",
            "Sr-Nd-Pb isotope",
            "Tectonic setting"
        ],
        "authors": [
            {
                "name": "Gang Liu",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Xuanhua Chen",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Shuwen Dong",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Zhengle Chen",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Shuqin Han",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Yi Yang",
                "org": "Xinjiang Bureau of Geological Exploration(Xinjiang Bureau of Geological Exploration),Urumqi,China"
            },
            {
                "name": "Baoying Ye",
                "org": "China University of Geosciences(China University of Geosciences),Wuhan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            }
        ],
        "venue": "Acta Petrologica Sinica",
        "year": 2012
    },
    "UZkpbXNn": {
        "id": "UZkpbXNn",
        "title": "Study on Serum Pro-inflammatory Cytokines Levels of Tumor Necrosis Factor-α,Interleukin-1β,Interleukin-8 in the Female Rats with Chronic Pelvic Inflammatory Disease by Traditional Chinese Medicine Therapy of Activating Blood to Remove Stasis",
        "abstract": "Objective:To investigate serum Pro-inflammatory cytokines levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),interleukin-8(IL-8)in the female rats with Chronic Pelvic Inflammatory Disease(CPID) by Traditional Chinese Medicine therapy of activating blood to remove stasis.Method:The method of mixed bacteria injection plus mechanical damage was used to established animal model of CPID.Sixty CPID model rats were randomly and evenly divided into five groups that included model group,High,Medium,Low dose experimental group and the control group,while twenty-four female rats were evenly divided into two groups as sham operation group and normal control group.The levels of TNF-α、IL-1β and IL-8 in serum were measured by Enzyme-linked immunosorbent assay.Result:(1)The levels of TNF-α,IL-8 in serum were much higher in model group than in normal control group、sham operation group(P<0.01),and the levels of that were much lower in medium dose experimental group than model group(P<0.01),and the levels of that were much lower in medium dose experimental group than in the control group(P<0.05),and the levels of that were much higher in high,low dose experimental group than in the control group(P>0.05 or P<0.01),and the levels of that were much lower in medium dose experimental group than in other two experimental group(P<0.01).(2)The levels of IL-1β in serum were much higher in model group than in normal control group,sham operation group(P<0.01),and the levels of that were much lower in high,medium dose experimental group than in model group(P<0.01),and the levels of that were much lower in high,medium dose experimental group than in the control group(P>0.05),and the levels of that were much lower in high、medium dose experimental group than in other experimental group(P<0.01).(3)According to Correlation Analysis,it was significant positive correlation between the levels of TNF-α,IL-1β,IL-8 in serum.Conclusion:The possible mechanism that Traditional Chinese Medicine therapy of activating blood to remove stasis cure CPID and prevent-mitigate pelvic adhesions is to restrain inflammation by influencing the levels of Pro-inflammatory cytokines in CPID rats serum.",
        "keywords": [
            "Traditional Chinese Medicine therapy of activating blood to remove stasis",
            "Pro-inflammatory cytokines in serum",
            "Chronic pelvic inflammatory disease"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ",et al.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "LIU Rui-fen",
                "org": ",et al.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "YANG Xiao-na",
                "org": ",et al.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            }
        ],
        "venue": "Medical Innovation of China",
        "year": 2012
    },
    "k8XdFS69": {
        "id": "k8XdFS69",
        "title": "Ultrahigh-Temperature/Ultrahigh-Pressure Scale Control for Deepwater Oil and Gas Production",
        "abstract": "",
        "keywords": [
            "oil and gas",
            "solubility"
        ],
        "authors": [
            {
                "name": "chunfang fan",
                "org": "rice university"
            },
            {
                "name": "wei shi",
                "org": "rice university"
            },
            {
                "name": "ping zhang",
                "org": "rice university"
            },
            {
                "name": "haiping lu",
                "org": "rice university"
            },
            {
                "name": "nan zhang",
                "org": "rice university"
            },
            {
                "name": "sarah work",
                "org": "rice university"
            },
            {
                "name": "hamad amer alsaiari",
                "org": "rice university"
            },
            {
                "name": "amy kan",
                "org": "rice university"
            },
            {
                "name": "mason b tomson",
                "org": "rice university"
            }
        ],
        "venue": "Spe Journal",
        "year": 2012
    },
    "UqCY3xPH": {
        "id": "UqCY3xPH",
        "title": "Concerted Evolution of Duplicate Control Regions in the Mitochondria of Species of the Flatfish Family Bothidae (Teleostei: Pleuronectiformes)",
        "abstract": "",
        "keywords": [
            "biology",
            "engineering",
            "physics",
            "chemistry",
            "medicine"
        ],
        "authors": [
            {
                "name": "donghe li",
                "org": "chinese academy of sciences"
            },
            {
                "name": "wei shi",
                "org": "chinese academy of sciences"
            },
            {
                "name": "thomas a munroe",
                "org": "national oceanic and atmospheric administration"
            },
            {
                "name": "li gong",
                "org": "chinese academy of sciences"
            },
            {
                "name": "xiaoyu kong",
                "org": "chinese academy of sciences"
            }
        ],
        "venue": "PLOS ONE",
        "year": 2015
    },
    "UtDRiTLn": {
        "id": "UtDRiTLn",
        "title": "Design and Implementation of Intelligent Temperature and Humidity Control System for Greenhouse",
        "abstract": "According to the problem that manual controlling process of temperature and humidity for greenhouse is complicated and low accuracy,an intelligent temperature and humidity control system for greenhouse used in agricultural production was designed.In view of the rural economic conditions and technological level,the system's detailed design is completely based on the principles of being pragmatic,good enough and simple operation.In hardware design,the system achieves its fault self-repair by innovatively using of double-watchdog circuit,protecting control system for a long time stable operation;in software design it uses PID control algorithm to control the system error less than 2%.Practical application has shown that the system is simple,high reliability,scalability,and helpful to reduce farmers' labor and increase crop yields.",
        "keywords": [
            "humidity",
            "greenhouse",
            "PID control",
            "double-watchdog",
            "temperature"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": "School of Electronic and Information Engineering,Liaoning Technical University,Fuxin ,PRC"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electronic and Information Engineering,Liaoning Technical University,Fuxin ,PRC"
            }
        ],
        "venue": "Hunan Agricultural Sciences",
        "year": 2011
    },
    "SEFcxc4A": {
        "id": "SEFcxc4A",
        "title": "Effect of indomethacin on endometrial morphology in intrauterine device users with bleeding disorders",
        "abstract": "Objective:To explore the endometrial morphological changes after treatment with indomethacin in the intrauterine device(IUD)users with bleeding disorders.Methods:Fourty-nine IUD users with bleeding disorders(the treatment group)and twenty women conducting hysterosalpingography cannula for tubal infertility and hysterectomy for hysteromyoma(the control group)were enrolled.Indomethacin was given orally to women in the treatment group.Different parts of endometrial tissues were obtained from the fixed points that contained the areas oppressed by IUD,close to IUD and away from IUD.The corresponding parts were selected in the control group.The gross,microscopic and ultramicro characteristics of the samples were observed and evaluated.Results:Compared with the control group,the microscopic and ultramicro characteristics of the treatment group were abnormal obviously,showing abnormalities and growth uncoordination caused by abnormal exfoliation and recovery of the endometrium before the treatment.The shorter the distance was,the severer the endometrial injury was.After the treatment,the abnormal exfoliation and recovery of the endometrium in the cured women disappeared or decreased,while it remained unchangeable in those who had not been cured.Conclusion:The abnormal exfoliation and recovery of the endometrium exists in the IUD users with side effect of bleeding disorders,which may be the pathogenesis of bleeding disorders in the IUD users.",
        "keywords": [
            "Endometrium",
            "Abnormal exfoliation and recovery",
            "Indomethacin",
            "Morphology",
            "Bleeding disorders",
            "Intrauterine device",
            "Side effects"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": ",et al.National TCM Clinical Research Center,Department of Gynecology and Obstetrics,Affiliated Hospital of Shandong University of TCM,JiNan "
            },
            {
                "name": "Liu Ruifen",
                "org": ",et al.National TCM Clinical Research Center,Department of Gynecology and Obstetrics,Affiliated Hospital of Shandong University of TCM,JiNan "
            },
            {
                "name": "Xu Li",
                "org": ",et al.National TCM Clinical Research Center,Department of Gynecology and Obstetrics,Affiliated Hospital of Shandong University of TCM,JiNan "
            }
        ],
        "venue": "Chinese Journal of Family Planning",
        "year": 2010
    },
    "nlDogJeu": {
        "id": "nlDogJeu",
        "title": "Reliability and validity of the Chinese version of the manual ability classification system for cerebral palsy",
        "abstract": "Objective To evaluate the reliability and validity of the Chinese version of Manual Ability Classification System (MACS).Methods Patients with cerebral palsy(CP) were involved from two rehabilitation centers in Shanghai. Three assessment methods were used to evaluate the manual function levels, including locale assessment by professional, locale assessment by family career and video assessment by professionals. Eight assessing scenes were set for these children to mimic the normal living activities, including drinking with cups, using spoon ,opening and closing small bottles, cleaning face, wringing towels, turning pages of a book, writing, and releasing buttons. Two occupational therapists did the locale assessments. All the activities performed by these children were videotaped and rescored by the same two occupational therapists and one physiatrist at least one week later (the longest interval between locale assessment and video assessment was 10 months). The family career read Chinese version of MACS then scored their children according to their performance at home and at locale as well. Professionals explained the terms for parents if needed but they didn′t discuss the classification results with parents. Test-retest reliability was analyzed by comparing scores of locale assessment and video assessment, Inter-tester reliability was analyzed by comparing scores of different estimator(family career,occupational therapist and physiatrist).Criterion-related validity was evaluated by comparing MACS levels with scores of Fine Motor Function Measure(FMFM) .Results One hundred and twenty-four children (77 males and 47 females; mean age: 6.7 years, SD: 2.6 years, age range: 4 to 18 years) with CP were involved from two rehabilitation centers in Shanghai. 97 children in the 4 to 7-year band, 24 children in the 8 to 12-year band, 3 children in the 13 to 18-year band. Types of CP in these children were spastic quadriplegia (n=27), spastic diplegia (n=48), spastic hemiplegia (n=38), athetotic (n=5),dystonia (n=4) and ataxic (n=2). Gross motor function classification system levels were: Ⅰ(n=51), Ⅱ(n=32),Ⅲ(n=15),Ⅳ(n=14),and Ⅴ (n=12). Chinese version of MACS was found to possess satisfactory test-retest reliability(ICC=0.94 and 0.87) as well as excellent inter-tester reliability (ICC=0.85-0.96). Criterion-related validity was moderate between MACS levels and scores of FMFM (Spearman r=-0.71).Conclusions This study extended reliability and validity of the Chinese version of MACS. Results indicated that Chinese version of MACS was a valid and reliable measure of manual functions in Chinese children with CP. Environment factors should be considered in assessment. Participation of family career in scoring was very valuable. With the help of family careers, the scores might reflect children′s practical manual function levels more precisely.",
        "keywords": [
            "Classification",
            "Reliability",
            "Validity",
            "Function",
            "Cerebral palsy"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Rehabilitation Center of Children′s Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": "Rehabilitation Center of Children′s Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "SU Yi",
                "org": "Rehabilitation Center of Children′s Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": "Rehabilitation Center of Children′s Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "WANG Su-juan",
                "org": "Rehabilitation Center of Children′s Hospital of Fudan University, Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Pediatrics",
        "year": 2009
    },
    "LGbTQwWE": {
        "id": "LGbTQwWE",
        "title": "Study of predictive validity and reliability of qualitative general movements assessment for neurological outcome in high risk neonates",
        "abstract": "Objective Prechtl's Qualitative general movements assessment(GMs assessement)was first applied in our clinical research in China.Predictive validity and reliability of GMs assessment for neurological outcome in high risk neonates were studied.Methods According to the inclusion and exclusion criteria,infants who took part in our follow-up clinic after discharged from our neonatal intensive care unit were confirmed as the participants.GMs recordings during preterm GMs and writhing movements period(at least once)and fidgety movements period(at least once)were collected and assessed.Neurological outcome was determined at least after one year old.Peabody Developmental Motor Scale-2(PDMS-2)was adopted to confirm the presence of motor retardation.Sensitivity,specificity,positive predictive value and negative predictive value were calculated.Interscorer reliability was tested in 12 infants by 30 observers.12 infants received a second assessment to assess test-retest reliability after a two month interval by 6 observers.Results 58(male 34,female 24)high risk neonates after follow-up(12-40 mos)were included as study participants.42(72%)preterm infants with an average gestational age as(31.4± 2.0)weeks and an average birth weight as(1 642 ±408)gram were included.16(28%)fullterm infants with an average gestational age as(38.6 ±1.1)weeks and an average birth weight as(3 401±365)gram were included.During preterm GMs and writhing movements period,115 GMs recordings with an average of(2.0 ±0.8)times per infant were collected.During fidgety movements period,89 GMs recordings with an average of(1.5 ±0.6)times per infant were collected.The neurological outcomes were as follows:7(12%)infants with spastic cerebral palsy,5(9%)infants with motor retardation and 46(79%)with normal motor development.In preterm GMs and writhing movements period,predictive validity was as follows:sensitivity 83%,specificity 78%,positive predictive value 50%,and negative predictive value 95%.In fidgety movements period,predictive validity was as follows:sensitivity 75%,specificity 98%,positive predictive value 90%,and negative predictive value 94%.GMs assessment was found to possess a good interscorer reliability(ICC:0.97-0.99)as well as a moderate test-retest reliability(ICC:0.69).Conclusions GMs assessment can be used in high risk infants within 4 to 5 months to give a reliable and valid prediction for later neurological outcome,especially for cerebral palsy.There existed a high interscorer reliability and moderate test-retest reliability in basic observers.As a non-invasive,non-intrusive,simple and economical neurological assessment tool,GMs assessment can be extensively used in China.",
        "keywords": [
            "Qualitative general movements assessment",
            "Reliability",
            "High risk neonates",
            "Outcome",
            "Predictive validity"
        ],
        "authors": [
            {
                "name": "YANG Hong",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "SHAO Xiao-mei",
                "org": "Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "WANG Yi",
                "org": ""
            },
            {
                "name": "CAO Yun",
                "org": "Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "WANG Su-juan",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "XU Xiu-juan",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "ZHANG Xu-dong",
                "org": "Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "LIAO Yuan-gui",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "LI Hui",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            },
            {
                "name": "ZHU Mo",
                "org": " Department of Child healthcare and Rehabilitation,2 Neonatal Department 3 Neurological department"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Pediatrics",
        "year": 2007
    },
    "Bo46fr7q": {
        "id": "Bo46fr7q",
        "title": "Variable message sign and dynamic regional traffic guidance",
        "abstract": "Traffic has always been the infrastructure of national economic and social development. With the pace of urbanization unprecedented speedup and the increase of vehicle possessions, traffic congestion has become a big problem in modern cities. Regional traffic guidance system provides traffic information for road travelers in pre-trip and in on-trip, and guides travelers to change travel modes, cho...",
        "keywords": [
            "Traffic control",
            "Navigation",
            "Telecommunication traffic",
            "Voice mail",
            "Vehicle dynamics",
            "Roads",
            "Partitioning algorithms",
            "Vehicles",
            "Environmental economics",
            "Cities and towns"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang University"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University"
            },
            {
                "name": "Shaolin Zhou",
                "org": "Zhejiang University"
            },
            {
                "name": "Ling Zhang",
                "org": "Zhejiang University"
            },
            {
                "name": "Zhi Tang",
                "org": "Zhejiang University"
            },
            {
                "name": "Yuyu Yin",
                "org": "Zhejiang University"
            },
            {
                "name": "Li Kuang",
                "org": "Zhejiang University"
            },
            {
                "name": "Zhaohui Wu",
                "org": "Zhejiang University"
            }
        ],
        "venue": "IEEE Intelligent Transportation Systems Magazine",
        "year": 2009
    },
    "p9AZCpMx": {
        "id": "p9AZCpMx",
        "title": "Fluxless heat spreader bonding with cold form solder",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "qing zhou",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "lwQTb7wa": {
        "id": "lwQTb7wa",
        "title": "The complete mitochondrial genome sequence of the giant clam Tridacna derasa (Tridacnidae: Tridacna)",
        "abstract": "AbstractThe complete mitochondrial genome of the giant clam Tridacna derasa was completely sequenced by high-throughput sequencing method. The total length of the complete mitogenome was 20,760bp, including 13 protein-coding genes, 23 transfer RNA genes, 2 ribosomal RNA genes and a non-coding control region. The base composition of the genome is 28.41% A, 36.92% G, 21.94% G and 12.74% C with a total GC content of 34.68%. Phylogenetic tree based on complete mitogenome sequences revealed that T.derasa was closely related to T.squamosa, both belonging to the Tridacna genus.",
        "keywords": "",
        "authors": [
            {
                "name": "Haitao Ma",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Lin Lin",
                "org": "South China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Guangzhou, China"
            },
            {
                "name": "Yuehuan Zhang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Shixi Chen",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Ziniu Yu",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "XMD4YtB8": {
        "id": "XMD4YtB8",
        "title": "The effect of ultrafiltration rate on the intradialytic hypotension in patients with end stage diabetic nephropathy",
        "abstract": "Objectives To evaluate the effect of ultrafiltration rate on the hypotension during hemodialysis session in patients with end stage diabetic nephropathy.Methods Seventy-three patients with end stage diabetic nephropathy receiving maintenance hemodialysis were selected in the study.They were treated with different dialysis modality,dialyzer,blood flow and ultrafiltration rate according to the individual condition.The occurrence of hypotension during hemodialysis session was analyzed.Results The intradialytic hypotension rate was 19.8%in patients with the individual ultrafiltration rate<10 ml/kg/h,and was 25.5%in patients with the rate>10ml/kg/h.Logistic regression analysis indicated that the individual ultrafiltration rate was an independent risk factor for intradialytic hypotension in patients with end stage diabetic nephropathy receiving maintenance hemodialysis.Conclusion A lower individual ultrafiltration rate can effectively reduce the occurrence of hypotension and can improve the tolerance to hemodialysis in patients with end stage diabetic nephropathy.",
        "keywords": [
            "Hypotension",
            "Individual ultrafiltration rate",
            "Diabetic nephropathy",
            "Hemodialysis"
        ],
        "authors": [
            {
                "name": "LI Rui-zhao",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "CHEN Yuan-han",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "XIA Yun-feng",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "LI Zhi-lian",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "LI Zhuo",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            },
            {
                "name": "SHI Wei",
                "org": ".Division of Nephrology & Blood Purification Center of Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou  China"
            }
        ],
        "venue": "Chinese Journal of Blood Purification",
        "year": 2011
    },
    "AVaeua78": {
        "id": "AVaeua78",
        "title": "An Experimental Research on the Effect of Self-Esteem and Self-presentation on Memory",
        "abstract": "According to the inconsistency-negativity neglect model,the interaction between the level of self esteem and the type of self presentation would be significant for the recall of self presentation information.The results of the experimental research on the 90 undergraduates support the hypothesis.The individuals made more recall errors for the inconsistency information with the level of self esteem than the consistency information.The results may supplement the phenomena of mnemic neglect.",
        "keywords": [
            "self-esteem",
            "memory",
            "self-presentation"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Journal of Southwest University(Social Sciences Edition)",
        "year": 2008
    },
    "DHiiuzS0": {
        "id": "DHiiuzS0",
        "title": "Indirect Measurement of Asynchronous Motors Based on Wavelet Ridge",
        "abstract": "The virtual data acquisition card and PC were employed to detect the stator current signal of the asynchronous motor while starts,and the current signal of 1st order gear harmonic was obtained by de-noising,filtering and rebuilding with the wavelet theory.With regard to the gradient characteristic of high frequencies,the transient frequency was extracted with the algorithm of wavelet ridge line to realize the indirect measurement for the non-torque and rotating speed sensors.Experimental results showed that method of the paper brings exact measurements and new views for detection of the starting characteristic of asynchronous motors.",
        "keywords": [
            "torque-rotating speed",
            "gradient signal",
            "wavelet ridge",
            "asynchronous motor"
        ],
        "authors": [
            {
                "name": "SONG Haijun",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "HUANG Chuanjin",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "CHEN Tiejun",
                "org": "School of Electric Engineering,ZhengZhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Electric Machines & Control Application",
        "year": 2012
    },
    "lo2s7eku": {
        "id": "lo2s7eku",
        "title": "Dynamic analysis of three-dimensional drivetrain system of wind turbine",
        "abstract": "In our previous study, a torsional model was used to perform a dynamic analysis of a wind turbine drivetrain. However, detailed characteristics could not be obtained with this torsional model. In this paper, the mathematical model of the wind turbine drivetrain is extended to a three-dimensional dynamic model. A typical arrangement with one low-speed planetary gear stage and two highspeed spur gear stages is used in this work. The governing equation of the drivetrain is derived by using Lagrange’s equation. Lagrange’s equation takes into account the kinetic energy of each component and potential energies from the shaft, bearing, and gear mesh. The governing equation is solved numerically using direct numerical integration. A dynamic analysis is carried out to investigate the transient response of the drivetrain system.",
        "keywords": [
            "Wind turbine",
            " Mathematical model",
            " Drivetrain",
            " Three-dimensional dynamics",
            " Dynamic loads"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": "konkuk university"
            },
            {
                "name": "hyunchul park",
                "org": "pohang university of science and technology"
            },
            {
                "name": "sangkwon na",
                "org": "posco"
            },
            {
                "name": "jinseop song",
                "org": "Korea Institute of Machinery & Materials,Daejon,South Korea"
            },
            {
                "name": "sangjin ma",
                "org": "konkuk university"
            },
            {
                "name": "changwan kim",
                "org": "konkuk university"
            }
        ],
        "venue": "International Journal of Precision Engineering and Manufacturing",
        "year": 2014
    },
    "KImAWFGX": {
        "id": "KImAWFGX",
        "title": "On the University Practical Teaching System",
        "abstract": "The university practical teaching is the method corresponding to the theory teaching,with such basic features as the,problem discussion depth of learning and critical reflection.Space complexity and purpose diversity determines various forms of practical teaching,with the logic system composed of course practice teaching,professional practice teaching and social practice teaching.",
        "keywords": [
            "social practice teaching",
            "course practical teaching",
            "professional practice teaching",
            "university practical teaching"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Education Science,Fuyang Normal College,Fuyang ,China"
            }
        ],
        "venue": "Journal of Higher Education",
        "year": 2013
    },
    "qVeSyydb": {
        "id": "qVeSyydb",
        "title": "The role of myeloperoxidase in evaluating hemodialysis-associated cardiovascular disease",
        "abstract": "Objectives To study the role of myeloperoxidase ( MPO) in evaluating hemodialysis-associated cardiovascular diseases. Methods In this cross-sectional study, 65 nondiabetic patients were investigated. The patients received hemodialysis therapy for at least 24 months and were not complicated with cardiovascular disease prior to the onset of hemodialysis. The relation between MPO activities and complicated cardiovascular disease was analyzed. Results Twenty-four of 65 patients developed different cardiovascular diseases after hemodialysis. There were no significant difference in age, gender and blood pressure between patients with and without cardiovascular disease. But there were a higher serum MPO activity and a higher serum concentration of C-reactive protein. The patients with higher MPO activities had a longer dialysis duration and higher serum concentration of C-reactive protein. The MPO activity was correlated to the dialysis duration and the serum concentration of C-reactive protein ( r =0.392, P =0.001; r = 0.306, P =0.013, respectively). In univariate logistic regression models, both the MPO activity and C-reactive protein serum concentration were risk factors of cardiovascular disease. The cardiovascular risk increased 23.5% for every increase of 10 units of MPO activity. After being adjusted by the C-reactive protein serum concentration in multivariate model, the elevated MPO activity of 10 units was attributed to an increased cardiovascular risk for 20.4%. Conclusions MPO activities which indicate the level of hemodialysis-associated inflammation and oxidative stress were associated with cardiovascular disease in hemodialysis patients.",
        "keywords": [
            "cardiovascular disease",
            "risk factor",
            "renal dialysis",
            "peroxidase"
        ],
        "authors": [
            {
                "name": "CHEN Yuan-han",
                "org": " Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou , China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou , China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": " Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou , China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": " Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou , China"
            },
            {
                "name": "FU Xia",
                "org": " Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou , China"
            }
        ],
        "venue": "South China Journal of Cardiovascular Diseases",
        "year": 2009
    },
    "I6iGQl1V": {
        "id": "I6iGQl1V",
        "title": "High current operation of a semi-insulating gallium arsenide photoconductive semiconductor switch triggering a spark gap",
        "abstract": "A transient peak current as high as 5.6 kA is obtained by a GaAs photoconductive semiconductor switch (PCSS) in series with a spark gap. Based on the characteristics of the GaAs PCSS, mechanisms of discharge between the PCSS and the spark gap are discussed. It is implied that a hybrid operation mode of photo-activated charge domain occurs due to the superposition of the bias voltage and the instantaneous radio frequency voltage.",
        "keywords": [],
        "authors": [
            {
                "name": "Ming Xu",
                "org": "Xian Univ Technol, Dept Appl Phys, Xian 710048, Peoples R China"
            },
            {
                "name": "Shi Wei",
                "org": "Xian Univ Technol, Dept Appl Phys, Xian 710048, Peoples R China"
            },
            {
                "name": "Lei Hou",
                "org": "Xian Univ Technol, Dept Appl Phys, Xian 710048, Peoples R China"
            },
            {
                "name": "Hong Xue",
                "org": "Xian Univ Technol, Dept Appl Phys, Xian 710048, Peoples R China"
            },
            {
                "name": "Shenjiang Wu",
                "org": "Xian Univ Technol, Dept Appl Phys, Xian 710048, Peoples R China"
            },
            {
                "name": "Huiying Dai",
                "org": "Air Force Engn Univ, Dept Sci, Xian 710051, Peoples R China"
            }
        ],
        "venue": "CHINESE PHYSICS LETTERS",
        "year": 2010
    },
    "sePSgMp9": {
        "id": "sePSgMp9",
        "title": "Design and Implementation of an Asynchronous Embedded Processor:TengYue-Ⅱ",
        "abstract": "In embedded systems,the power consumption of processors is restricted to a low limit.Asynchronous circuit techniques can be effective methods to design low power processors.In order to meet the performance and power requirements of the multimedia applications in embedded systems,a low power asynchronous microprocessor named \"TengYue-Ⅱ\" is designed and implemented.A 32-bit on-chip bus,two transport triggered architecture cores,two memory controllers and several communication interfaces form the processor.One processor core is based on asynchronous circuits and the other one is its synchronous counterpart.TengYue-Ⅱ processor is implemented in the UMC 0.18μm CMOS technology and the supply voltage is 1.8V.The area of the chip is 4.89mm×4.89mm.The experimental results show that both cores can run correctly at the frequency of 200MHz and the asynchronous core's power consumption is lower than 50% of the synchronous core.",
        "keywords": [
            "asynchronous circuit",
            "low power",
            "transport triggered architecture",
            "embedded multimedia application"
        ],
        "authors": [
            {
                "name": "SU Bo",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG Zhi-ying",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "REN Hong-guang",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG You-rui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            }
        ],
        "venue": "Computer Engineering & Science",
        "year": 2012
    },
    "BoQuEY5N": {
        "id": "BoQuEY5N",
        "title": "A Strategic Analysis of the Regional Industrial Structure Modulation and Development of Northern Anhui Province During the 12th Five-Year Program",
        "abstract": "It is well known that the regional industrial structure including its distribution and gradation in Northern Anhui Province was very low,and its economy development level was relatively lagging during the last decades.It is a mission for the government to re-energize the economy development of Northern Anhui Province so as to promote the whole province's economy rise sharply.Therefore,the government sectors of Northern Anhui Province should excavate both the inner and outer capacity to reconfirm their regional industrial structure.This article coped with the strengthes,weaknesses,opportunities,and threats for the economy development of Northern Anhui Province through the conventional SWOT analysis,and put forward strategic suggestions for Northern Anhui Province in the new period.",
        "keywords": [
            "Northern Anhui Province",
            "SWOT",
            "Industrial structure",
            "Industrial transferring"
        ],
        "authors": [
            {
                "name": "ZHANG Ke-rong",
                "org": "School of Economics and Administration"
            },
            {
                "name": "LIU Wu-yi",
                "org": "Research Department of Fuyang Teachers College,Fuyang ,Anhui"
            },
            {
                "name": "SHI Wei",
                "org": "Research Department of Fuyang Teachers College,Fuyang ,Anhui"
            },
            {
                "name": "CHEN De-yu",
                "org": "Research Department of Fuyang Teachers College,Fuyang ,Anhui"
            }
        ],
        "venue": "Journal of Fuyang Teachers College(Social Science Edition)",
        "year": 2012
    },
    "gzHcKhxy": {
        "id": "gzHcKhxy",
        "title": "Clinical observation on therapeutic effect of Yishenhuoxue decoction integrated with western medicine on lupus nephritis",
        "abstract": "Objective To observe the therapeutic effect of Yishenhuoxue decoction combined with western medicine on lupus nephritis.Methods 60 patients with lupus nephritis(LN)were randomly divided into two groups.30 patients in control group were treated by hormones and cyclophosphamide;The other 30 patients in treatment group were treated similarly plus Yiqihuoxue decoction.The activity parameters of LN,urinary protein,liver function,serum anti-ds-DNA,complete C3,C4 were evaluated in both groups before and after the treatment.Results The total effective rate in treatment group was 93.3%,which was 80% in control group,there was a significant difference between two groups(P<0.05);there were significant differences in urinary protein,liver function,serum anti-ds-DNA,complete C3,C4 in both groups before and after the treatment(P<0.05 or P<0.01);after the treatment there was a significant difference in these parameters between treatment group and control group(P<0.05),and those in treatment group were superior to those of control group;there were significant differences in the incidence of adverse reaction and recurrence after treatment between two groups(P<0.05),and those in treatment group was lower than those in control group.Conclusion Yiqihuoxue decoction is effective in treating lupus nephritis,which can reduce the side effects of western medicines and decrease complications and recurrent rate.",
        "keywords": [
            "Lupus nephritis",
            "Integrated treatment of TCM with western medicine"
        ],
        "authors": [
            {
                "name": "XIANG Caichun",
                "org": ",et al.Nephrology department,No.1 Affiliated Hospital of Guangxi TCM College,Guangxi,Nanning "
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Nephrology department,No.1 Affiliated Hospital of Guangxi TCM College,Guangxi,Nanning "
            },
            {
                "name": "WANG Qihang",
                "org": ",et al.Nephrology department,No.1 Affiliated Hospital of Guangxi TCM College,Guangxi,Nanning "
            }
        ],
        "venue": "Hebei Journal of Traditional Chinese Medicine",
        "year": 2008
    },
    "YduuR0Jv": {
        "id": "YduuR0Jv",
        "title": "An Experimental Research about Self-Esteem's Memory Effect",
        "abstract": "The experimental research confirms the existence of the pattern of self-esteem's memory effect,that is,the interaction between self-esteem level and adjective valence had a significant effect on the recall of trait adjectives.Specifically,for the positive adjectives,high self-esteem individuals remembered significantly more than did low self-esteem individuals,but for the recall of negative adjectives,high self-esteem and low self-esteem individuals did not have significant difference.For the high self-esteem individuals,the positive adjectives were recalled significantly more than negative adjectives,but for the low self-esteem individuals,the recall of positive adjectives and negative adjectives did not have significant difference.The experimental results support the inconsistency-negativity neglect model.",
        "keywords": [
            "self-esteem",
            "self-esteem's memory effect"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": " School of Culture and Social Development Studies,Southwest University,Chongqing,"
            },
            {
                "name": "Huang Xiting",
                "org": " School of Psychology,Southwest University,Chongqing,"
            }
        ],
        "venue": "Psychological Science",
        "year": 2007
    },
    "ehgP3CkV": {
        "id": "ehgP3CkV",
        "title": "Reliability of direct method and video method of qualitative general movements assessment",
        "abstract": "【Objective】 Reliability of direct method and video method of qualitative general movements(GMs) assessment and its related clinical significance were studied. 【Methods】 High risk neonates and young infants in our follow-up clinic were included as participants.Direct method and video method of GMs assessment were applied and reliability was analyzed. 【Results】 For video method,interscorer ICC was 0.78～0.83 and test-retest ICC was 0.68～0.90.Interscorer ICC of direct method was 0.78～0.85.Test-retest ICC between direct and video methods was 0.87～0.90(P<0.05). 【Conclusions】 Video and direct methods of GMs assessment possess good stability.Combination of two methods in clinic will promote the simple and quick advantages of GMs assessment,which will be suitable for the extensive use in pediatrics.",
        "keywords": [
            "cerebral palsy",
            "reliability",
            "high risk neonates",
            "qualitative general movements assessment"
        ],
        "authors": [
            {
                "name": "YANG Hong",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "SHAO Xiao-mei",
                "org": "2 Neonatal Department,"
            },
            {
                "name": "WANG Yi",
                "org": "3 Neurological Department,Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "SHI Wei",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "XU Xiu-juan",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "CAO Yun",
                "org": "2 Neonatal Department,"
            },
            {
                "name": "WANG Su-juan",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "LIAO Yuan-gui",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "ZHU Mo",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "LI Hui",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            },
            {
                "name": "SU Yi",
                "org": "1 Department of Child Health Care and Rehabilitation,"
            }
        ],
        "venue": "Chinese Journal of Child Health Care",
        "year": 2008
    },
    "AtYkteTO": {
        "id": "AtYkteTO",
        "title": "The Basic rules of Sinicization of Western Philosophy",
        "abstract": "While regarding\"Sinicization of Western Philosophy\"as a new paradigm of gradually studying Western Philosophy,we should face up to these questions at first:What's the process and the rules of\"Sinicization of Western Philosophy\"?How can we push on\"Sinicization of Western Philosophy\".So,it will be a very significative work,which summarizes the progress of\"Sinicization of Western Philosophy\",summarizing the basic rules of modernization,traditional culture and age matters,and forecasting the trend of development of Sinicization of Western Philosophy.",
        "keywords": [
            "Basic Rules",
            "Modernization Process",
            "Thought Pattern Innovation",
            "Sinicization of Western Philosophy"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Journal of Northeast Normal University(Philosophy and Social Sciences)",
        "year": 2013
    },
    "rLZFjmMs": {
        "id": "rLZFjmMs",
        "title": "Integrated circuit package to provide high-bandwidth communication among multiple dice",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qing zhou",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "85PdXJW0": {
        "id": "85PdXJW0",
        "title": "STRATIGRAPHY AND PALAEOCLIMATOLOGY AROUND 5700aBP AT THE FOOT OF BAOHUA MOUNTAIN OF JURONG,SOUTHERN JIANGSU",
        "abstract": "Integrative study of buried peat and fossil trees in the lower reaches of the Yangtze River,analysis of sedimentary characteristics and environmental geochemistry of the middle and late Holocene strata in the Pukou and Linfengqiao areas in Nanjing,and research on sedimentary facies and pollen-spore climate curves around 5 700aBP in the Baohua Mountain area near Jurong of southern Jiangsu indicate that a dry-cold event occurred in this area around 5 700aBP.During this dry-cold interval,the lowest average annual temperature in the Baohua Mountain area was 12.56 ℃,and the lowest average annual precipitation was 716.40 mm.This event can also be verified by the abnormal variations in the content of clay and iron concentrations in the corresponding layers of the Linfengqiao profile,which is not only an abnormal reflection on regional palaeoclimate,but also shows the responsive characteristics of global change.",
        "keywords": [
            "Jurong",
            "Quaternary",
            "palaeoclimate",
            "dry-cold event",
            "Baohua Mountain",
            "Jiangsu",
            "Holocene"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " 1) Institute of Oceanographic and Geographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "WANG Fu-bao",
                "org": " 1) Institute of Oceanographic and Geographic Sciences,Nanjing University,Nanjing "
            },
            {
                "name": "HAN Hui-you",
                "org": " 1) Institute of Oceanographic and Geographic Sciences,Nanjing University,Nanjing "
            }
        ],
        "venue": "Journal of Stratigraphy",
        "year": 2008
    },
    "JuDF54Zb": {
        "id": "JuDF54Zb",
        "title": "Adolescent Romantic Relationships: Research Orientation,Methods, and Influencing Factors",
        "abstract": "Adolescent romantic relationships refer to mutually acknowledged ongoing voluntary interactions, commonly marked by intense expressions of affection and perhaps current or anticipated sexual behavior. The research orientation mostly include biosocial orientation, cognitive representations orientation, and development-contextual orientation. Currently, there are three validated research methods: self-report, observation method, and video recall method. Some of researches have focused on dealing with influencing factors of adolescent romantic relationships, such as individual factors, interpersonal factors and social factors. Adolescent romantic relationships research arena is still in its infancy, thus, further studies integrating research theoretically are essential, with the stability of relationships quality, mechanisms of microsystem and representative sampling.",
        "keywords": [
            "interpersonal factors",
            "video recall method",
            "development-contextual orientation",
            "adolescent romantic relationships"
        ],
        "authors": [
            {
                "name": "YANG Lin-Pei",
                "org": "School of Culture and Social Development Studies, Southwest University, Chongqing , China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies, Southwest University, Chongqing , China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2011
    },
    "tQCBCszp": {
        "id": "tQCBCszp",
        "title": "A self-adaptive test framework for concurrent programs",
        "abstract": "In this paper, we describe a new test framework for concurrent programs. Testing on concurrent programs remains difficult due to the non-deterministic nature of concurrent programs. Approaches are proposed to surmount this difficulty. However, few of them are really effective. A new self-adaptive test framework is proposed to alleviate this problem, since it is impossible to solve it completely. This framework which is based on the study of concurrent test points tests each concurrent program like a circuit, while concurrent test points like components of the circuit. The original reason of concurrent bugs stems from the resource sharing among multiple processes or threads. Therefore, a controller is introduced in the framework to increasingly intensify resource competition via test data controlling, aiming to trigger concurrent bugs' emerging sooner once they exist.",
        "keywords": [
            "concurrent test point",
            "concurrent program",
            "test data",
            "new self-adaptive test framework",
            "multiple process",
            "resource competition",
            "non-deterministic nature",
            "concurrent bug",
            "resource sharing",
            "new test framework",
            "adaptive testing"
        ],
        "authors": [
            {
                "name": "Manna Wu",
                "org": "Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Bo Zhou",
                "org": "Zhejiang University, Hangzhou, China"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University, Hangzhou, China"
            }
        ],
        "venue": "MEDES",
        "year": 2009
    },
    "J3TsM7uL": {
        "id": "J3TsM7uL",
        "title": "The Modular Design of a Low-voltage Power Line Carrier Based on ST7538",
        "abstract": "In this paper,on the basis of studying the low-voltage power line carrier technology home and aboard and referring to a great deal of related information,a practical low-voltage power line carrier system is built with the core of ST7538.Hardware of the system is thoroughly analyzed and some software work is done at the same time.In addition,communication effect of the system is respectively tested in the lab and in field environment.A design scheme of carrier modem is supplied whose control objects are family electrical equipments such as electric lamps.",
        "keywords": [
            "low-voltage power line carrier communication",
            "PLC Modem",
            "hardware"
        ],
        "authors": [
            {
                "name": "LEI Gang",
                "org": "College of Engineering and Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "College of Engineering and Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "ZHANG Xiao-min",
                "org": "College of Engineering and Technology,Zhongzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhongzhou University",
        "year": 2012
    },
    "HwkCy3tq": {
        "id": "HwkCy3tq",
        "title": "Research on the Embedded SoftPLC Technology",
        "abstract": "This paper introduces the concepts and features of the embedded system and softPLC,and advances the whole design thought of the embedded softPLC.",
        "keywords": [
            "softPLC",
            "industrial control",
            "embedded system"
        ],
        "authors": [
            {
                "name": "WANG Jing-hui",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "Y3B7v94w": {
        "id": "Y3B7v94w",
        "title": "Prospective study of cystatin C for diagnosis of acute kidney injury after cardiac surgery]",
        "abstract": "Objective To prospectively study the value of cystatin C in diagnosis of acute kidney injury (AKI) in patients after cardiac surgery. Methods A total of 132 patients undergoing cardiopulmonary bypass were enrolled in this prospectively study. From each patient, blood samples were collected everyday before and after operation to detect the serum creatinine (Scr) and cystatin C levels by enzymatic method and particle-enhanced turbidimetric immunoassay (PETIA), respectively, and the glomerular filtration rate (eGFR) was estimated using MDRD equation. AKI diagnosis was made according to the RIFLE criteria of the Acute Dialysis Quality Initiative (ADQI) (R: Scr increased by ≥50%; I: Scr increased by ≥100%; F: Scr increased by ≥200%; L: Loss of kidney function; E: End-stage renal disease). Another AKI diagnostic criterion was also adopted according to the levels of cystatin C increment, namely an increase by ≥50%, ≥100%, and ≥200%. Results Twenty-nine patients (21.9%) developed AKI of varied severities, including 10 meeting the R-criteria, 12 the I-criteria, 7 the F-criteria, with the other 103 patients without AKI serving as the control group. Cystatin C of the 29 AKI patients was drastically increased in comparison with that of the control group (P<0.001). Significant linear correlation was found between cystatin C and Scr (r=0.732, P<0.001) and between [cystatin C]-1 and estimated GFR (R=0.803, P<0.001). By the two diagnostic criteria based on cystatin C and Scr levels, respectively, the median diagnostic time of AKI was 2 days (range 1-4 days) and 3 days (range 2-5 days) for R criteria (10 patients, P=0.014), 3.5 days (range 1-6 days) and 5 days (range 2-8 days) for I criteria (12 patients, P=0.008), and 5 days (range 3-7 days) and 6.5 days (range 4-9 days) for F criteria (7 patients, P=0.02), respectively. ROC analysis confirmed excellent accuracy of cystatin C in AKI diagnosis (AUC=0.992). With the cut-off value of cystatin C increment by ≥50%, the diagnostic sensitivity and specificity of AKI was 92% and 95%, respectively.Conclusion Cystatin C can serve as a good indicator for AKI diagnosis to allow earlier detection of AKI than Scr-based diagnosis in patients after cardiac surgery.",
        "keywords": [
            "prospective study",
            "acute kidney injury",
            "diagnosis",
            "cystatin c"
        ],
        "authors": [
            {
                "name": "Xin-lin Liang",
                "org": "Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou 510080, China. xinlingliang@yahoo.com"
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Shuang-xin Liu",
                "org": ""
            },
            {
                "name": "Li-jun Yan",
                "org": ""
            },
            {
                "name": "Hui-jie Xuan",
                "org": ""
            },
            {
                "name": "Wei-ping Xiong",
                "org": ""
            },
            {
                "name": "Yan-qiang Peng",
                "org": ""
            },
            {
                "name": "Jin-song Huang",
                "org": ""
            },
            {
                "name": "Yong-zheng Liang",
                "org": ""
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2008
    },
    "2Z9rxdn4": {
        "id": "2Z9rxdn4",
        "title": "Study on Suppression of Switching Overvoltage Caused by Operation of Disconnector in GIS",
        "abstract": "Base on the structural characteristic of GIS, the mechanism and effects of disconnector with shunt resistor to depress VFTO are simulated and analyzed in this paper. Through the research, it is concluded that because the closing resistor of the disconnector can depress VFTO, the amplitude of VFTO in GIS is low, so it will not endanger the insulation of GIS, including its connecting equipment and control device in secondary side. But because the frequency of VFTO in GIS is very high, the insulation of the equipment with windings, such as transformers, can be influenced.",
        "keywords": [
            "Disconnector",
            "GIS",
            "Shunt resistor",
            "VFTO"
        ],
        "authors": [
            {
                "name": "RUAN Quan-rong",
                "org": "School of Electrical Engineering, Xi'an Jiaotong University, Xi'an , China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering, Xi'an Jiaotong University, Xi'an , China"
            },
            {
                "name": "WANG Liang",
                "org": "School of Electrical Engineering, Xi'an Jiaotong University, Xi'an , China"
            }
        ],
        "venue": "High Voltage Apparatus",
        "year": 2006
    },
    "se93Q8e4": {
        "id": "se93Q8e4",
        "title": "Influence of environmental variability on phylogenetic diversity and trait diversity within Calligonum communities",
        "abstract": "Since phylogenetic data provide the evolutionary history of the species and traits are the result of adaptation to the environmental conditions, joint analysis of these two aspects and ecological data may illuminate that how ecological processes affect the evolution of species and assembly of communities. In this study, we compared the community structure of sibling communities in order to illuminate the influence of environmental variability. We chose different Calligonum communities as research subjects which grow in active sand dunes and stabilized sand fields. Our results show that species which co-occurred in C. rubicundum community have greater phylogenetic evenness compared to species in other communities where co-occurring plants had similar traits. Soil variability might legitimately explain this result. Based on the similarity between the pattern of trait diversity and the pattern of phylogenetic diversity, we inferred that the evolution of traits is conservative and species of all but C. rubicundum communities are under more intense selection pressure. ",
        "keywords": [
            "Calligonum",
            "community composition",
            "ecological process",
            "phylogenetic community structure",
            "phylogenetic signal"
        ],
        "authors": [
            {
                "name": "jiancheng wang",
                "org": ""
            },
            {
                "name": "honglan yang",
                "org": ""
            },
            {
                "name": "xiyong wang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "borong pan",
                "org": ""
            }
        ],
        "venue": "EXCLI journal",
        "year": 2014
    },
    "JyPyvMbZ": {
        "id": "JyPyvMbZ",
        "title": "A label-free and universal platform for the construction of an odd/even detector for decimal numbers based on graphene oxide and DNA-stabilized silver nanoclusters.",
        "abstract": "Molecular logic devices with different functions can perform various tasks in the areas of biological molecule detection, disease diagnosis, multivariate analysis, and bioimaging. Herein, a series of logic circuits based on silver nanoclusters (AgNCs)/graphene oxide (GO) are constructed to execute nonarithmetic functions, including 3-, 4-, and 5-bit odd/even checking. The resulting devices can differentiate between even and odd decimal numbers in the range from 0 to 31. Moreover, the devices can be expanded to operate with wider ranges of numbers when more inputs are added. The signal reporter is structured using AgNCs and GO, preventing laborious modification of biomolecules. The designed DNA-based logic nanodevices share the same DNA platform and a constant threshold value, showing great potential for application in information processing at the molecular level. Additionally, these devices can stably carry out their logic operations in a biological matrix, indicating that the AgNC/GO-based system can operate in a complicated biological environment. Given the biocompatibility and design flexibility of DNA, this study provides novel outcomes towards the development of label-free intelligent nanodevices. This may open a new path for the application of AgNCs/GO in molecular logic circuits and fluorescence imaging.",
        "keywords": "",
        "authors": [
            {
                "name": "Siqi Zhang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, China. hdmtzc@126.com."
            },
            {
                "name": "Kun Wang",
                "org": "College of Sciences, Northeastern University,Shenyang,China"
            },
            {
                "name": "Kai-Bin Li",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            },
            {
                "name": "Fengzao Chen",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            },
            {
                "name": "Wen-Ping Jia",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            },
            {
                "name": "Jie Zhang",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            },
            {
                "name": "De-Man Han",
                "org": "Department of Chemistry, Taizhou University,Jiaojiang,China"
            }
        ],
        "venue": "Nanoscale",
        "year": 2017
    },
    "wVriF7v5": {
        "id": "wVriF7v5",
        "title": "Research and practice on the exploratory physics experiment teaching",
        "abstract": "Contents and methods of research-oriented experiment teaching are investigated,based on the analysis of students' knowledge level.Exploratory experimental teaching programm is raised and the corresponding contents and mode are discussed.The research achievements and experiences are summarized.",
        "keywords": [
            "designing experiment",
            "practical teaching",
            "innovative education",
            "physics experiment"
        ],
        "authors": [
            {
                "name": "XIE Guang-yong",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Physics Experimentation",
        "year": 2009
    },
    "nhMN8nvr": {
        "id": "nhMN8nvr",
        "title": "Electrochemical Exfoliation of Graphite into Nitrogen-doped Graphene in Glycine Solution and its Energy Storage Properties",
        "abstract": "Abstract   Electrochemically anodic exfoliation of graphite has been developed for nitrogen-doped few-layer graphene sheets (N-FLGS), demonstrating high N-doping levels of 6.05 atom%. The process for the preparation of N-FLGS is involved with the intercalation of glycine anions H 2 NCH 2 COO −  into the graphite layers, electro-polymerization of large electro-oxidation products H 2 NCH 2 CONHCH 2  − , and  in situ  N-doping in the graphite layer. Transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and Raman spectroscopy were employed to characterize the structure and properties of the N-FLGS. The as-fabricated N-FLGS utilized as electrode materials for supercapacitor exhibit enhanced electrochemical performance, including excellent cycling stability (the capacitance ratios after 10 000 cycles is 96.1%) and a remarkable rate capability (184.5 F g −1  at 1 A g −1 , 132.7 F g −1  at 50 A g −1 ).",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchang Yang",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren 554300, China"
            },
            {
                "name": "Wei Shi",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren 554300, China"
            },
            {
                "name": "Renhui Zhang",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren 554300, China"
            },
            {
                "name": "Chunhong Luan",
                "org": "Clean Energy Materials and Engineering Center, School of Microelectronics and Solid-state Electronics, University of Electric Science and Technology of China, Chengdu 611731, China"
            },
            {
                "name": "Qing Zeng",
                "org": "Clean Energy Materials and Engineering Center, School of Microelectronics and Solid-state Electronics, University of Electric Science and Technology of China, Chengdu 611731, China"
            },
            {
                "name": "Chao Wang",
                "org": "Clean Energy Materials and Engineering Center, School of Microelectronics and Solid-state Electronics, University of Electric Science and Technology of China, Chengdu 611731, China"
            },
            {
                "name": "Simin Li",
                "org": "College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China"
            },
            {
                "name": "Zhaodong Huang",
                "org": "College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China"
            },
            {
                "name": "Hanxiao Liao",
                "org": "College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China"
            },
            {
                "name": "Xiaobo Ji",
                "org": "College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China"
            }
        ],
        "venue": "Electrochimica Acta",
        "year": 2016
    },
    "aorTqlGx": {
        "id": "aorTqlGx",
        "title": "Ultra-Fast Photoconductive Switches' Transient Resistance Calculation Method",
        "abstract": "By electromagnetic theory,the induced current and the conduction current in the output current of photoconductive switches(PCSS) been studied.It is found that the displacement current can created by the moving built-in field and the electric voltage shifting from the PCSS to the load.We consider that the displacement current can created by the moving built-in field current in the large gap PCSS can be neglected,and the output current of large gap PCSS's relies largely on the conduction current formed by the absorption of photo-production carriers and the displacement current created by the electric voltage shifting from the PCSS to the load.A total current mode is built based on the transportation of the photogenerated carriers and the transient electromagnetism process.In contrast with conductivity mode,the transient resistance of PCSS is described accurately by the new mode.",
        "keywords": [
            "displacement current",
            "photoconductive switches(PCSS)",
            "total current mode"
        ],
        "authors": [
            {
                "name": "QU Guang-hui",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "JIA Wan-li",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2009
    },
    "6GJzoerq": {
        "id": "6GJzoerq",
        "title": "Analysis of Two Different Logic Styles Against DPA Attacks",
        "abstract": "Differential-power-analysis attacks are currently the most effective on cryptographic devices.In such attacks,the power consumption of a cryptographic device is analyzed to reveal the secret key that is used inside the device.In order to counteract these attacks,DPA-resistant standard cells,instead of the static complementary CMOS standard cells,can be used to implement cryptographic devices.This paper analyzes the resistance of two different logic styles(DDCVSL and SABL)against DPA attacks in the design rules of two different process technologies.The experimental results demonstrate that DDCVSL and SABL all have a high DPA-resistance with the shrinking channel-length of the transistors.Meanwhile,the power consumption,delay and area of DDCVSL are less than those of SABL.",
        "keywords": [
            "differential power analysis(DPA)",
            "sense amplifier based logic(SABL)",
            "process technology",
            "dynamic differential cascade voltage switch logic(DDCVSL)"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "DAI Kui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "TONG Yuan-man",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "GONG Rui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG Zhi-ying",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            }
        ],
        "venue": "Computer Engineering & Science",
        "year": 2007
    },
    "nH0Mwg5T": {
        "id": "nH0Mwg5T",
        "title": "Preventing and curing mechanism of Gongqing granum on lochiorrhea after administrated with mifepristone and misoprostol",
        "abstract": "AIM To investigate the mechanism of Gongqing granum, a traditional Chinese medicine, on lochiorrhea after administrated with mifepristone and misoprostol in human early pregnancy.METHODS The selected 240 subjects were randomly divided into group A, B, C, and D.In group A, subjects took mifepristone, misoprostol, and Gongqing granum.In group B, subjects took RU-486, misoprostol and Qianzhi granum.In group C, subjects took mifepristone and misoprostol only.In group D, subjects received artificial abortion operation.The specimen of the 4 groups were collected, the change of apoptosis rate(AR) was observed by the method of TUNEL, and the expressions of Fas, FasL, Caspase-8, and Caspase-3 were observed by the method of immunohistochemistry.RESULTS Compared to the other 3 groups, AR and the expressions of Fas, FasL, Caspase-8 and Caspase-3 of group A were obviously higher(P < 0.05 or P < 0.01) .CONCLUSION Gongqing granum can promote the signal transduction of Fas and FasL, activate the cascade reaction of caspase, consequently induce the cell apoptosis of chorionic and decidua in human early pregnancy, so as to prevent and cure lochiorrhea after drug abortion by mifepristone and misoprostol.",
        "keywords": [
            "decidua",
            "prolonged lochia",
            "Gongqing granum",
            "apoptosis",
            "chorion"
        ],
        "authors": [
            {
                "name": "LI Xia",
                "org": "Key Laboratory for Tumor Immunity and Traditional Chinese Drug Immunity, Shandong Province Medical Science Shandong Academy of Medical Sciences, Ji-nan SHANDONG , China"
            },
            {
                "name": "LIU Rui-fen",
                "org": "Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji-nan SHANDONG , China"
            },
            {
                "name": "SHI Wei",
                "org": "Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji-nan SHANDONG , China"
            },
            {
                "name": "WANG Li",
                "org": "Key Laboratory for Tumor Immunity and Traditional Chinese Drug Immunity, Shandong Province Medical Science Shandong Academy of Medical Sciences, Ji-nan SHANDONG , China"
            },
            {
                "name": "SUN Jian-li",
                "org": "Laizhou Municipal People' s Hostipal, Laizhou SHANDONG , China"
            },
            {
                "name": "ZHOU Xian-bin",
                "org": "Key Laboratory for Tumor Immunity and Traditional Chinese Drug Immunity, Shandong Province Medical Science Shandong Academy of Medical Sciences, Ji-nan SHANDONG , China"
            },
            {
                "name": "GUO Yu-qi",
                "org": "Key Laboratory for Tumor Immunity and Traditional Chinese Drug Immunity, Shandong Province Medical Science Shandong Academy of Medical Sciences, Ji-nan SHANDONG , China"
            },
            {
                "name": "YAO Cheng-fang",
                "org": "Key Laboratory for Tumor Immunity and Traditional Chinese Drug Immunity, Shandong Province Medical Science Shandong Academy of Medical Sciences, Ji-nan SHANDONG , China"
            }
        ],
        "venue": "Chinese Journal of New Drugs and Clinical Remedies",
        "year": 2009
    },
    "RzzZGxVO": {
        "id": "RzzZGxVO",
        "title": "Design, synthesis and biological evaluation of N-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide derivatives as novel P-glycoprotein inhibitors reversing multidrug resistance.",
        "abstract": "The overexpression of P-glycoprotein plays an important role in the process of multidrug resistance (MDR). P-gp inhibitors are one of the effective strategies to reverse tumor MDR. Novel P-gp inhibitors with phthalazinone scaffolds were designed, synthesized and evaluated. Compound 26 was found to be the most promising for further study. Compound 26 possessed high potency (EC50= 46.2 +/- 3.5 nM) and low cytotoxicity. 26 possessed high MDR reversal activity towards doxorubicin-resistant K56/A02 cells. Reversal fold (RF) value reach to 44.26. 26 also increased accumulation of doxorubicin (DOX or ADM) or other MDR-related anticancer drugs with different structures. In conclusion, compound 26 deserves more research for its good features as P-gp inhibitor.",
        "keywords": [
            "Multidrug resistance",
            "P-glycoprotein inhibitors",
            "Doxorubicin"
        ],
        "authors": [
            {
                "name": "Qianqian Qiu",
                "org": "Yancheng Teachers Univ, Sch Pharm, Jiangsu Prov Key Lab Coastal Wetland Bioresources, Yancheng 224007, Peoples R China"
            },
            {
                "name": "Jiaqi Zhou",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Mutta Kairuki",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenglong Huang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOORGANIC CHEMISTRY",
        "year": 2019
    },
    "N0ybPSPp": {
        "id": "N0ybPSPp",
        "title": "Load analysis and comparison of different jacket foundations",
        "abstract": "",
        "keywords": [
            "offshore wind energy"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            },
            {
                "name": "chinwha chung",
                "org": ""
            },
            {
                "name": "jaeha baek",
                "org": ""
            },
            {
                "name": "youngchan kim",
                "org": ""
            },
            {
                "name": "changwan kim",
                "org": ""
            }
        ],
        "venue": "Renewable Energy",
        "year": 2013
    },
    "5miseipu": {
        "id": "5miseipu",
        "title": "The effect of bovine parathyroid hormone withdrawal on MC3T3-E1 cell proliferation and phosphorus metabolism.",
        "abstract": "Hypocalcemia and hypophosphatemia are common complications after parathyroidectomy (PTX). Sudden removal of high circulating levels of parathyroid hormone (PTH) causes decreased osteoclastic resorption resulting in a decreased bone remodeling space. These phenomena are likely due to an increased influx of calcium and phosphorus into bone. However, there are currently no data to support this hypothesis. In this study, we found that PTX significantly reduced levels of PTH, calcium and phosphate. Compared with preoperative levels, after 1 year, postoperative PTH, calcium and phosphate levels were 295.6 ± 173.7 pg/mL (P < 0.05), 86.62 ± 15.98 mg/dL (P < 0.05) and 5.56 ± 2.03 mg/dL (P < 0.05), respectively. We investigated continuous bovine PTH administration as well as withdrawal of bovine PTH stimulation in the mouse osteoblast precursor cell line MC3T3-E1. MC3T3-E1 cells were cultured with continuous bovine PTH treatment for 20 days or with transient bovine PTH treatment for 10 days. High doses of continuous bovine PTH exposure strongly reduced cell proliferation, alkaline phosphatase activity and the number of mineralized calcium nodules. However, withdrawal of bovine PTH (100 ng/mL) significantly increased the number of mineralized calcium nodules and caused a rapid decline in calcium and phosphorus content of culture medium. In conclusion, continuous exposure to bovine PTH inhibited osteoblast differentiation and reduced the formation of mineralized nodules. However, this inhibition was removed and mineralized nodule formation resumed with withdrawal of bovine PTH. According to the results of our clinical examinations and in vitro experiments, we hypothesize that the sudden removal of high levels of PTH may cause an increased influx of calcium and phosphorus into bone after PTX.",
        "keywords": [],
        "authors": [
            {
                "name": "Shuangxin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Weiping Zhu",
                "org": "Department of Nephrology, the Fifth Affiliated Hospital of Sun Yat-sen University, No.52 Meihua Road, Zhuhai, China."
            },
            {
                "name": "Sijia Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Tongxia Cui",
                "org": "Department of Nephrology, the Fifth Affiliated Hospital of Sun Yat-sen University, No.52 Meihua Road, Zhuhai, China."
            },
            {
                "name": "Zhonghe Li",
                "org": "Department of Nephrology, the Fifth Affiliated Hospital of Sun Yat-sen University, No.52 Meihua Road, Zhuhai, China."
            },
            {
                "name": "Bin Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Zhuo Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Jianxiong Wu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Zheng Lin",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, China."
            }
        ],
        "venue": "PloS one",
        "year": 2015
    },
    "nWp3YR6a": {
        "id": "nWp3YR6a",
        "title": "Research on Improving the Performance of On-load Voltage Regulation by Mechanical Reactive Compensation in Distribution System",
        "abstract": "The on-load voltage regulation with transformer can not guarantee the demand of reactive power.In this paper,it is considered that reactive compensation equipment can be used for voltage regulation.A model of 110 kV distribution system is simulated,the effects of on-load voltage regulation with transformer and with reactive compensation are compared,the superiority of on-load voltage regulation with reactive compensation combined with transformer is analyzed.Finally,it points out that some problems should be resolved when using mechanical reactive compensation equipment in power system.",
        "keywords": [
            "EMTP computation",
            "On-load voltage regulation with transformer",
            "Reactive compensation",
            "Voltage quality"
        ],
        "authors": [
            {
                "name": "SUN Dong-hui",
                "org": "Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "FENG Bin",
                "org": "Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "JIA Lei",
                "org": "Xi′an Jiaotong University,Xi′an "
            },
            {
                "name": "SHI Wei",
                "org": "Xi′an Jiaotong University,Xi′an "
            }
        ],
        "venue": "Power Capacitor",
        "year": 2006
    },
    "LbKGgpkE": {
        "id": "LbKGgpkE",
        "title": "Optimization on Temperature Sampling Programs",
        "abstract": "Xiamen Yudian Company can manufacture AI Artificial Intelligence series regulator,and provide sample codes for the regulator.In this article,the sample codes are analyzed to improve the execution speed.The new codes can reduce Hard Disk wear and tear,which will give a good reference for coding field.",
        "keywords": [
            "Serial Port",
            "hard disk wear",
            "temperature"
        ],
        "authors": [
            {
                "name": "Zhang Lixin",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Zhang Yong",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Jia Xin",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Wang Wei",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Shi Wei",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            }
        ],
        "venue": "Engineering & Test",
        "year": 2010
    },
    "KZL6KMBg": {
        "id": "KZL6KMBg",
        "title": "Effects of reduced pH and elevated pCO2 on sperm motility and fertilisation success in blood clam, Tegillarca granosa",
        "abstract": "ABSTRACTAlthough it has been shown that ocean acidification generally has a negative impact on fertilisation success of broadcast spawning marine organisms, whether induced fertilisation success reduction is a consequence of elevated pCO2 or decreased pH remains unclear. Therefore, the impacts of HCl- and CO2-induced acidified seawater on sperm motility and gametes fertilisation capability of a broadcast spawning bivalve species, Tegillarca granosa were investigated in the present study. The results showed that the fertilisation capability of both gametes was significantly reduced in either HCl- or CO2-acidified seawater. In addition, significant impacts on sperm motility were observed in the group exposed to CO2-acidified seawater, suggesting that this parameter is sensitive to pCO2 instead of solely pH value. The differences between the two seawater acidification manipulating methods may be due to the intrinsic difference in diffusion capability of CO2 and protons.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Xinguo Zhao",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Cheng Guo",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Saixi Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Yichen Wang",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            },
            {
                "name": "Xueliang Chai",
                "org": "Zhejiang Mariculture Research Institute, Wenzhou, People’s Republic of China"
            },
            {
                "name": "Wandong Fu",
                "org": "Zhejiang Marine Development Research Institute, Zhoushan, People’s Republic of China"
            },
            {
                "name": "Huicheng Yang",
                "org": "Zhejiang Marine Development Research Institute, Zhoushan, People’s Republic of China"
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, People’s Republic of China"
            }
        ],
        "venue": "New Zealand Journal of Marine and Freshwater Research",
        "year": 2017
    },
    "a4nGvR7M": {
        "id": "a4nGvR7M",
        "title": "The Value of Miniprobe Endoscopic Ultrasonography in the Diagnosis of Duodenal Submucosal Lesions",
        "abstract": "Objective:To evaluate the usefulness of miniprobe endoscopic ultrasonography(mEUS)in the diagnosis of duodenal submucosal lesions.Methods:Following gastroendoscopy with no definite diagnosis made,69 patients with 71 duodenal submucosal lesions subsequently received mEUS,and the results were analyzed.Results:Of 71 lesions,33 were diagnosed ultrasonographally as cyst,15 gastrointestinal stromal tumor(GIST),8 adipoma,2 mucous adenoma,1 angioma,respectively.The accurate rate of diagnosis based on mEUS was 88.9%.Conclusion:mEUS has great value in the diagnosis of duodenal submucosal lesions.",
        "keywords": [
            "Diagnosis",
            "Duodenum",
            "Submucosal lesion",
            "Endoscopic ultrasonography"
        ],
        "authors": [
            {
                "name": "SUN Xiaobin",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,"
            },
            {
                "name": "ZHAO Cong",
                "org": "The Second People's Hospital of Chengdu City,Chengdu "
            },
            {
                "name": "XI Weidong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,"
            },
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,"
            }
        ],
        "venue": "Chinese Journal of Clinical Medicine",
        "year": 2008
    },
    "LDxY3osI": {
        "id": "LDxY3osI",
        "title": "Phylogenetic relationship of Cynoglossinae based on COI barcoding marker",
        "abstract": "Based on cytochrome oxidase subunit I(COI) barcoding marker of 33 flatfishes in the subfamily Cynoglossinae of Pleuronectiformes,the molecular phylogenetic trees were constructed by maximum likelihood and Bayesian inference method for the Cynoglossus phylogenetic analysis.The results showed that fishes of Cynoglossinae are one monophyletic group,which has a stable sister-group relationship with Symphurinae.In the taxa of this study,fishes of Paraplagusia clustered into a shallow branch,forming a late specialization group of Tongue soles.The genus Cynoglossus was divided into eight main branches.Species composition of these eight branches differs from that in the classification system based mainly on morphological characters,including numbers of lateral lines and nostrils.The species in four branches were similar to four groups(canariensis,heterolepis,arel,and cynoglossus) out of the six from Menon's system based on the morphological characteristics,while the kopsii group showed a great difference in branches classification.In addition,the K2P genetic distances among the eight branches of Cynoglossus were bigger than those in Paraplagusia subgenus,which indicates a further split among species or subgenus.The data of K2P genetic distance analysis also revealed that the Cynoglossus lighti Norman is a junior synonym of Cynoglossus joneri Günther,and that Cynoglossus purpureomaculatus Regan is a junior synonym of Cynoglossus abbreviatus(Gray).",
        "keywords": [
            "Paraplagusia",
            "Pleuronectiformes",
            "synonym",
            "K2P genetic distance",
            "Cynoglossus"
        ],
        "authors": [
            {
                "name": "MIAO Xian-guang",
                "org": ""
            },
            {
                "name": "JIANG Jin-xia",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "WANG Zhong-ming",
                "org": ""
            },
            {
                "name": "WANG Shu-ying",
                "org": ""
            },
            {
                "name": "KONG Xiao-yu",
                "org": ""
            }
        ],
        "venue": "Journal of Tropical Oceanography",
        "year": 2013
    },
    "q4q97W77": {
        "id": "q4q97W77",
        "title": "LASERS, OPTICS, AND OPTOELECTRONICS 1623 Fabrication of planar optical waveguides by electrical microcontact printing",
        "abstract": "",
        "keywords": [
            "microcontact printing",
            "optical waveguide"
        ],
        "authors": [
            {
                "name": "daniel b wolfe",
                "org": ""
            },
            {
                "name": "j christopher love",
                "org": ""
            },
            {
                "name": "byron d gates",
                "org": ""
            },
            {
                "name": "george m whitesides",
                "org": ""
            },
            {
                "name": "richard s conroy",
                "org": ""
            },
            {
                "name": "mara prentiss",
                "org": ""
            },
            {
                "name": "karen asatryan",
                "org": ""
            },
            {
                "name": "tigran v galstian",
                "org": ""
            },
            {
                "name": "zhanshan wang",
                "org": ""
            },
            {
                "name": "li wang",
                "org": ""
            },
            {
                "name": "yonggang wu",
                "org": ""
            },
            {
                "name": "lingyan chen",
                "org": ""
            },
            {
                "name": "xiaoshuang chen",
                "org": ""
            },
            {
                "name": "wei lu",
                "org": ""
            },
            {
                "name": "koichiro shirota",
                "org": ""
            },
            {
                "name": "hongbo sun",
                "org": ""
            },
            {
                "name": "satoshi kawata",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "yujie j ding",
                "org": ""
            },
            {
                "name": "qi zhang",
                "org": ""
            },
            {
                "name": "k pita",
                "org": ""
            },
            {
                "name": "l p zuo",
                "org": ""
            },
            {
                "name": "satoshi takahashi",
                "org": ""
            },
            {
                "name": "a v kolobov",
                "org": ""
            },
            {
                "name": "anatoly rogalev",
                "org": ""
            },
            {
                "name": "f wilhelm",
                "org": ""
            },
            {
                "name": "n jaouen",
                "org": ""
            },
            {
                "name": "tatsushi shima",
                "org": ""
            },
            {
                "name": "junji tominaga",
                "org": ""
            },
            {
                "name": "franco n c wong",
                "org": ""
            },
            {
                "name": "joung kyu park",
                "org": ""
            },
            {
                "name": "chang hae kim",
                "org": ""
            },
            {
                "name": "seung hyok park",
                "org": ""
            },
            {
                "name": "hee dong park",
                "org": ""
            },
            {
                "name": "se young choi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2004
    },
    "FjC5twNe": {
        "id": "FjC5twNe",
        "title": "Frequency characteristics of arc voltage on extra high voltage transmission line",
        "abstract": "Considering the importance of the status of secondary arc to the single-phase auto-reclosure of extra high voltage transmission line, a novel approach based on the harmonic of faulted phase is proposed to determine the arc status, where the characteristics of the prime and secondary arcs and the oscillation of the faulted phase with different compensation levels are analyzed, then the total harmonic distortion (THD) is introduced to reflect the harmonic content of the faulted phase. The EMTP simulations at different compensation levels indicate that after the arc extinction, the THD of the faulted phase gets distinctly low to judge arc status.",
        "keywords": [
            "Compensation level",
            "Extra high voltage transmission line",
            "Secondary arc",
            "Single-phase auto-reclosure",
            "Total harmonic distortion"
        ],
        "authors": [
            {
                "name": "Liang Shu",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Lei Jia",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Shipu Zheng",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Donghui Sun",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 2007
    },
    "fvwbQ1z3": {
        "id": "fvwbQ1z3",
        "title": "Effects of grounding resistance on secondary arc current in extra-high-voltage transmission lines",
        "abstract": "Empirical numerical value of grounding resistance is often used in secondary arc current calculation. The effects of grounding resistance on secondary arc current are analysed by use of the Thevenin theorem. The method of secondary arc extinction determines whether or not the grounding resistance needs to be modeled in detail. The grounding resistance has little effect on secondary arc current in transmission line with and without shunt compensation, while it should be considered in transmission line where high speed grounding switches (HSGS) are used. It is also verified by the calculation of electromagnetic transient program (EMTP).",
        "keywords": [
            "Grounding resistance",
            "Secondary arc current",
            "Single-pole autoreclosure"
        ],
        "authors": [
            {
                "name": "Yanhua Han",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 2002
    },
    "uduz6KFb": {
        "id": "uduz6KFb",
        "title": "The expression pattern of ADP-ribosyltransferase 3 in rat traumatic brain injury.",
        "abstract": "Mammalian ecto ADP-ribosyltransferases (ARTs) can regulate the biological functions of various types of cells by catalyzing the transfer of single ADP-ribose moiety from NAD+ to a specific amino acid in a target protein. ART3 is a member of the known ART family which is involved in cell division, DNA-repair and the regulation of the inflammatory response. To elucidate the expression, cellular localization and possible functions of ART3 in central nervous system (CNS) lesion and repair, we performed an acute traumatic brain injury model in adult rats. Western blot analysis showed that the expression of ART3 in ipsilateral brain cortex increased, then reached a peak at day 3 after traumatic brain injury (TBI), and gradually declined during the following days. But in the contralateral brain cortex, no obvious alterations were observed. Immunohistochemistry revealed the highly significant accumulation of ART3 at the ipsilateral brain in comparison to contralateral cerebral cortex. Double immunofluorescence labeling suggested that ART3 was localized mainly in the plasmalemma of neurons, but not in astrocytes or microglias within 3 mm from the lesion site at day 3 post-injury. In addition, we detected the expression profiles of caspase-3 and growth associated protein 43 (GAP-43) whose changes were correlated with the expression profiles of ART3 in this TBI model. Besides, co-localization of ART3/active caspase-3 and ART3/GAP43 were detected in NeuN-positive cells, respectively. Moreover, Pheochromocytoma (PC12) cells were treated with H₂O₂ to establish an apoptosis model. The results showed that the expression of ART3 was increased in the concentration and time dependence way. To further examine the involvement of ART3 in apoptosis of PC12, 3-Methoxybenzamide was used in flow cytometry analysis of apoptotic cells stained with Annexin V and PI. The experimental group in which 3-Methoxybenzamide used had a relative low level of apoptotic index compared with the untreated group. Together with previous reports, we hypothesize that ART3 may play important roles in CNS pathophysiology after TBI and further research is needed to have a good understanding of its function and mechanism.",
        "keywords": [
            "ART3",
            " Traumatic brain injury",
            " Apoptosis",
            " GAP43",
            " Neurons",
            " Rat"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province 226001, People's Republic of China."
            },
            {
                "name": "Peipei Gong",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Jian Fan",
                "org": "Department of Neurosurgery,Affiliated Qidong People Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Yao Hua Yan",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Lanchun Ni",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Xiaohong Wu",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Gang Cui",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Xinmin Wu",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Xingxing Gu",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery, Surgical Comprehensive Laboratory,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            }
        ],
        "venue": "Journal of molecular histology",
        "year": 2012
    },
    "S9SVGdP1": {
        "id": "S9SVGdP1",
        "title": "Effect of pulse high volume hemofiltration for treatment of multiple organ dysfunction syndrome]",
        "abstract": "To evaluate the effects of pulse high volume hemofiltration (PHVHF) in the treatment of multiple organ dysfunction syndrome (MODS).Twenty-five patients with MODS received treatment with PHVHF.The 25 patients showed significantly decreased BUN, Scr, and K(+) levels after the treatment (P<0.01), and PaO(2)/FiO(2) was improved in almost all the patients (P<0.05). The APACHEII scores were significantly improved (P<0.05) in these patients and 18 of them were cured and discharged. PHVHF therapy was associated with a survival rate of 72%.PHVHF can be effective for treatment of MODS.",
        "keywords": [
            "intensive care unit",
            "pulse high-volume hemofiltration",
            "multiple organ dysfunction syndrome"
        ],
        "authors": [
            {
                "name": "Li Li",
                "org": "Graduate School,Southern Medical University,Guangzhou ,China;Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Yi-lin Liu",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Ying Li",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Cui-hua Yang",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Ming-qing Rao",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Lian-ying Ma",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "Dao-xi Deng",
                "org": "Yuebei People's Hospital,Shaoguan ,China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2011
    },
    "WwIrUZvF": {
        "id": "WwIrUZvF",
        "title": "Black defect-engineered TiO 2 nanocrystals fabricated through square-wave alternating voltage as high-performance anode materials for lithium-ion batteries",
        "abstract": "Abstract   Black defect-engineered TiO 2  nanocrystals have been successfully fabricated via electrochemical square-wave alternating voltage method. Repeated redox of Ti foil surface accompanying vigorous hydrogen evolution plays a key role on the formation of the black TiO 2  nanocrystals. Transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and Brunauer-Emmett-Teller specific surface area are utilized to characterize the structure and properties of the products. When utilized as anode materials for lithium-ion batteries, the black TiO 2  nanocrystals electrode exhibits a high reversible capacity of 271 and 266 mAh g −1  after 200 cycles at 0.5 C (1 C = 168 mA g −1 ), as well as a good rate capability, which are likely to be associated with small particle size (ca. 6 nm), surface/interfacial pseudocapacitive lithium storage and increased electronic conductivity contributed from Ti 3+  defects.",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchang Yang",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren, 554300, China"
            },
            {
                "name": "Wei Shi",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren, 554300, China"
            },
            {
                "name": "Shijia Liao",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren, 554300, China"
            },
            {
                "name": "Renhui Zhang",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren, 554300, China"
            },
            {
                "name": "Senlin Leng",
                "org": "College of Material and Chemical Engineering, Tongren University, Tongren, 554300, China"
            }
        ],
        "venue": "Journal of Alloys and Compounds",
        "year": 2018
    },
    "crrV9QKL": {
        "id": "crrV9QKL",
        "title": "Clinical Study on “Tianqi Injection” in Treating Chronic Renal Failure",
        "abstract": "To investigate the therapeutic effect of Tianqi Injection on treating chronic renal failure(CRF)and its possible mechanism. 52 patients with CRF were randomized into the treating group(n=28) and the control group(n=24). Base on the routine therapy, Tianqi Injection was used to the treating group additionally, and Amino Acid Injection was used to the control group, 4 weeks constituted one treatment course. The changes of clinical symptoms, renal function and interleukin-8 (IL-8) were observed before and after treatment. Results: The total effective rate was 85.71% in treating group and 58.33% in control group (P<0.01). After treatment, the serum levels of indexes of renal function and IL-8 were significantly decreased in 2 groups after treatment (P<0.05 or P<0.01), and the effect of treating group was better than that in the control group(P<0.05 or P<0.01). Conclusion: It was suggested that Tianqi Injection could improve renal function of patients with CRF, and delay CRF progression by decreasing inflammation factors such as IL-8,inhibiting these inflammation factor damaging the kidney.",
        "keywords": [
            "Tianqi Injection",
            "Chronic renal failure",
            "Interleukin-8"
        ],
        "authors": [
            {
                "name": "WU Jin-yu",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "HUANG Xue-xia",
                "org": ""
            },
            {
                "name": "TANG Nong",
                "org": ""
            },
            {
                "name": "XIANG Cai-chun",
                "org": ""
            },
            {
                "name": "LIANG Jing-song",
                "org": ""
            }
        ],
        "venue": "Shanghai Journal of Traditional Chinese Medicine",
        "year": 2005
    },
    "p1okQi0T": {
        "id": "p1okQi0T",
        "title": "The expression of RANK and RANKL in kidney tissue of 5/6 subtotal nephrectomy rats and related effects of valsartan treatment",
        "abstract": "Objective To investigate the expression of receptor activator of NF-kappa B (RANK) , its ligand (RANKL) and osteoprotegerin (OPG) in kidney tissue of 5/6 subtotal nephrectomy (STNx) rats, and the effect of valsartan on above expression. Methods Seventy-two male SD rats were divided into STNx control group (n=24), STNx + valsartan treatment group (n=24) and sham operation group (n=24). In valsartan treatment group, the SD rats received valsartan (15 mg·kg-1·d-1) , an angiotensinⅡtype 1(AT1) receptor antagonist, after STNx. At week 4, 8 and 12 after operation, the kidney pathology was examined by light microscopy respectively. RANK, RANKL and OPG expression in kidney tissue was examined by histochemisty, Western blot and RT-PCR. Serum levels of RANKL and OPG were examined by ELISA at week 12. Results (1)At week 12 after operation, the 24-hour urine protein was (13.4±1.2) mg in valsartan group, (19.0±1.5) mg in STNx group and (6.1±0.6) mg in sham operation group (all P<0.01). (2)Glomerular sclerosis degree in valsartan treatment group was gentler than that in STNx group. (3)In sham operation rat kidneys, RANK and RANKL protein expressed in a few tubules and were absent in glomeruli. RANK and RANKL mRNA expressed in glomeruli in valsartan group and STNx group. Treatment with valsartan manifestly reduced mRNA and protein expression of RANK and RANKL in glomeruli (P < 0.01). There was no differences of OPG expression among these 3 groups. Serum levels of OPG and RANKL were similar in 3 groups at week 12. Conclusions RANK and RANKL may play a role in progressive renal injury following STNx. Inhibition of RANK and RANKL expression may be one of the mechanisms by which AT1 receptor antagonist attenuates renal injury after renal ablation.",
        "keywords": [
            "Receptor activator of NF-kappa B",
            "Ligand",
            "Nephrectomy",
            "Angiotensin receptor antagonist"
        ],
        "authors": [
            {
                "name": "LIU Shuang-xin",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "SHI Wei",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "LI Heng",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "YE Zhi-ming",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "WANG Wen-jian",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "HE Chao-sheng",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "LIU Yan-hui",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "HU Xiang-ming",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "ZHANG Bin",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "PENG Yan-qiang",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            },
            {
                "name": "YU Xi-yong",
                "org": ". Department of Nephrology, People's Hospital of Guangdong Province , Guangzhou, , China"
            }
        ],
        "venue": "Chinese Journal of Nephrology",
        "year": 2006
    },
    "IMX4jhJy": {
        "id": "IMX4jhJy",
        "title": "Evaluation of continuous venous-venous hemofiltration combined with coupled plasma filtration adsorption for treatment of systemic inflammation response syndrome with acute renal failure]",
        "abstract": "To evaluate the clinical efficacy of continuous venous-venous hemofiltration (CVVH) combined with coupled plasma filtration adsorption (CPFA) in the management of systemic inflammation response syndrome (SIRS) complicated by acute renal failure (ARF).Thirty patients with SIRS complicated by ARF (including 25 with severe acute pancreatitis, 2 with colonic perforation with infection, and 3 with acute infective endocarditis) were randomly divided into CVVH plus CPFA group (n=14) and CVVH alone group (n=16). The APACHE II score, mean arterial pressure, PaO2/FiO2, TNF-alpha and IL-10 were detected prior to or after the intervention. The feasibility and tolerance of CVVH plus CPFA and the therapy-related adverse reactions were evaluated.The two groups showed no significant differences in the baseline clinical characteristics (P>0.05). The mean arterial pressure and PaO2/FiO2 increased significantly after treatment as compared with the control (P<0.05), with TNF-alpha being reduced and IL-10 elevated. In CVVH plus CPFA group, APACHEII score improved significantly after 10 days (P<0.05). No therapy-related adverse reactions were noted, suggesting good tolerance of CVVH plus CPFA.CVVH combined with CPFA is an effective and safe method for improving the clinical outcome of patients with SIRS and ARF.",
        "keywords": [
            "continuous venous-venous hemofiltration",
            "acute renal failure",
            "coupled plasma filtration adsorption",
            "systemic inflammation response syndrome"
        ],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China;Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China;Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "Chao-sheng He",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Xing-ling Liang",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Shuang-xin Liu",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Yong-zheng Liang",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2010
    },
    "91oGI75g": {
        "id": "91oGI75g",
        "title": "Reliability and validity of Peabody Developmental Motor Scale in assessment of infants and toddlers",
        "abstract": "[Objective] To investigate the reliability and validity of Chinese version of Peabody Developmental Motor Scale(PDMS-2) in infants and toddlers,which will help providin basis for the application of this assessment in the field of high risk infants follow-up and early rehabilitation. [Methods] 100 children were recruited as participants who had been assessed by PDMS,15～31 of which were recruited for the test-retest reliability. with a interval of 4~7 days and 15～32 of which were selected for interscorer reliability. Parallel validity was analyzed by calculating the correlations between different raw scores of PDMS and Bayley Scales of Infant Development(BSID-Ⅱ) of 59 children. [Results] Different raw scores of PDMS possess excellent test-retest and interscorer reliabilities(ICC>0.90). Good parallel validity(Pearson r=0.66~0.91) was found between different raw scores of PDMS and BSID. [Conclusion] Reliability and validity of Chinese version of PDMS-2 was determined in this study,which would lay important basis for the application of PDMS-2 in the field of high risk infants follow-up and early rehabilitation.",
        "keywords": [
            "infants and toddlers",
            "validity",
            "reliability",
            "assessment",
            "Peabody Developmental Motor Scale"
        ],
        "authors": [
            {
                "name": "YANG Hong",
                "org": "1 Department of Child Rehabilitation,"
            },
            {
                "name": "SHI Wei",
                "org": "1 Department of Child Rehabilitation,"
            },
            {
                "name": "WANG Su-juan",
                "org": "1 Department of Child Rehabilitation,"
            },
            {
                "name": "LI Hui",
                "org": "1 Department of Child Rehabilitation,"
            },
            {
                "name": "LUO Dan-dan",
                "org": "1 Department of Child Rehabilitation,"
            },
            {
                "name": "WANG Yi",
                "org": "2 Neurological Department,Children's Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Child Health Care",
        "year": 2010
    },
    "rFYH46Cb": {
        "id": "rFYH46Cb",
        "title": "Research on Agricultural Sci-tech Team Promoting Building of a New Socialist Countryside",
        "abstract": "The great course of the building of socialist new countryside has drawn a blueprint for the realization of a moderately prosperous society.In order to achieve this goal,strong support from all walks of life in the society is needed.In such a case,agriculture-related colleges and institutes hold unshrinkable responsibility.Taking the fact that the agricultural college takes part in the construction of socialist new countryside in an unconventional organizational form as an example,this paper introduces the exploration & practice on science and technology team construction and team innovation of the college in the course of building a new socialist countryside based on Team Theories.During team building,the college has made remarkable achievements in scientific research,technology popularization,serving local economy,promoting the building of a new socialist countryside and so on.Researches and practice have proved that the organizational form of agricultural science and technology team is one of the effective forms to promote the construction of socialist new countryside.This study would provide helpful references for agricultural colleges and scientific research institutes to serve agriculture,rural areas,farmers and the work of building a new socialist countryside.",
        "keywords": [
            "sci-tech team",
            "building a new socialist countryside",
            "research"
        ],
        "authors": [
            {
                "name": "Mao Jian",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Wang Hui",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Xu Dasheng",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Zhou Dawei",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Yu Ning",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Fu Anjing",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            },
            {
                "name": "Shi Wei",
                "org": "Chengdu Vocational College of Agricultural Science & Technology,Wenjiang Chengdu "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2009
    },
    "IY15D6mX": {
        "id": "IY15D6mX",
        "title": "Unconditionally Stable FDTD Algorithm Based on Split-Step Scheme for the Analysis of Oblique Incident Plane Wave on Periodic Structures",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Xinbo Qu",
                "org": ""
            },
            {
                "name": "Bihua Zhou",
                "org": ""
            },
            {
                "name": "Nan Zhang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Yang Xiang",
                "org": ""
            }
        ],
        "venue": "Frequenz",
        "year": 2015
    },
    "Zrpe5ksh": {
        "id": "Zrpe5ksh",
        "title": "Cardiovascular risk profile in systemic lupus erythematosus: a cross-sectional study of 879 patients]",
        "abstract": "To investigate the prevalence of cardiovascular diseases (CVD) in patients with systemic lupus erythematosus (SLE) and estimate the associated risk factors for CVD.This cross-sectional study was conducted in 879 SLE patients treated in our hospital between March, 2006 and March, 2011. The demographic data and the clinical data including SLE duration, therapeutic regimen, renal pathological data, estimated glomerular filtration rate (eGFR), SLE Disease Activity Index (SLEDAI), and associated biochemical parameters were analyzed. Cardiovascular ultrasound was used for detecting and analyzing the cardiovascular structural and functional abnormalities.Eighty-five cases of CVD were found in the 879 SLE cases (9.7%). After age stratification, CVD was identified in 5.8%, 9.0%, 14.0% and 20.0% in SLE patients aged ≤19, 20-39, 40-59 and ≥60 years, respectively, showing a tendency to increase with age (P=0.002). The prevalence of CVD differed significantly between patients with and those without lupus nephritis (P=0.001). Among the 85 patients with CVD, 23.5% (20/85) had left ventricular hypertrophy, 49.5% (42/85) had congestive heart failure, 20.0% (17/85) had stroke, 3.5% (3/85) had angina pectoris, and 3.5% (3/85) had peripheral CVD. Compared to those without CVD, patients with CVD had a longer SLE duration (P=0.002), a longer time of steroids treatment (P=0.026), a higher blood pressure (P=0.0006), a lower eGFR (P=0.001), and a lower concentration of HDL (P=0.007). Logistic regression analysis showed that SBP, eGFR, HDL, SLE duration, SLEDAI index, serum C3 and hs-CRP were the risk factors for CVD in SLE patients (P=0.033).SLE is associated with a high risk of CVD which increases with age, and SLE patients with lupus nephritis have an even higher risk for CVD. SBP, eGFR, HDL, SLE duration, SLEDAI index, serum C3 and hs-CRP are the risk factors for CVD in SLE patients.",
        "keywords": [
            "multivariate logistic regression analysis",
            "cardiovascular diseases",
            "systemic lupus erythematosus",
            "risk factors"
        ],
        "authors": [
            {
                "name": "Chao-sheng He",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Wei Shi",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Zhi-ming Ye",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Xin-ling Liang",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Bin Zhang",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "Shuang-xin Liu",
                "org": " Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangzhou ,China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2011
    },
    "JBzc4YnE": {
        "id": "JBzc4YnE",
        "title": "Temporal Self-Appraisals",
        "abstract": "Self-appraisals include not only the assessment of current self,but also the retrospective assessment of past self and prospective assessment of future self.People are motivated to maintain or enhance present self-regard.They can do so byevaluating a subjectively recent self favorably,a subjectively distant past self unfavorably,especially on important attributes.Regarding a favorable past self/outcome as recent,an unfavorable past self/outcome as distant.The effect of the past on evaluations of current self depends on subjective distance;subjectively recent past directly affects current appraisals;subjectively distant past has little or contrasting influence.Additionally,the perception of improvement between the past and the present extends into the future.The asymmetry in the subjective distance of negative and positive events has a parallel pattern for future events.Finally,it pointed out four prospects for the future research,such as close relationships,special groups,cultural differences in subjective distance of past event,the underlying mechanism of the asymmetry in the subjective temporal distance.",
        "keywords": [
            "present self",
            "past self",
            "temporal self-appraisal",
            "future self",
            "subjective temporal distance"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            },
            {
                "name": "HUANG Gang",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Journal of Southwest University(Social Sciences Edition)",
        "year": 2010
    },
    "C1l1nseX": {
        "id": "C1l1nseX",
        "title": "Evolutionary response to the Qinghai-Tibetan Plateau uplift: Phylogeny and biogeography of Ammopiptanthus and tribe Thermopsideae (Fabaceae)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Pei-Liang Liu",
                "org": "College of Life Sciences, Northwest University, Xi’an, Shaanxi, China"
            },
            {
                "name": "Lei Duan",
                "org": "Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, Guangdong, China"
            },
            {
                "name": "Borong Pan",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Institute of Ecology and Geography in Xinjiang, The Chinese Academy of Sciences, Urumqi, Xinjiang, China"
            },
            {
                "name": "Zhihao Su",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Institute of Ecology and Geography in Xinjiang, The Chinese Academy of Sciences, Urumqi, Xinjiang, China"
            }
        ],
        "venue": "PeerJ",
        "year": 2017
    },
    "7OqNzWy7": {
        "id": "7OqNzWy7",
        "title": "Investigation of Terahertz Continuous Wave Imaging and Pulse Wave Imaging",
        "abstract": "In this paper,the principle of THz continuous wave imaging and THz pulse wave imaging are introduced.THz continuous wave and THz pulse wave imaging system developed self-independently are reported.In continuous wave imaging,the glow discharge detector(GDD) developed by our group and a commercial Schottky diodes are used as the detectors for THz continuous wave imaging,and the results indicate that GDD is a potential THz continuous wave room-temperature detector with low cost and high imaging quality.In THz pulse imaging,the SI-GaAs photoconductive antenna developed by our group is used as a pulse THz source to carry out the pulse imaging of a metal ring.The THz amplitude imaging and phase imaging at different frequencies are analyzed.",
        "keywords": [
            "glow discharge detector(GDD)",
            "pulse wave imaging",
            "continuous wave imaging",
            "Terahertz wave"
        ],
        "authors": [
            {
                "name": "CHEN Suguo",
                "org": "Faculty of Science,Xi’an University of Technology,Xi’an ,China"
            },
            {
                "name": "HOU Lei",
                "org": "Faculty of Science,Xi’an University of Technology,Xi’an ,China"
            },
            {
                "name": "LOU Xiao",
                "org": "Faculty of Science,Xi’an University of Technology,Xi’an ,China"
            },
            {
                "name": "DONG Chengang",
                "org": "Faculty of Science,Xi’an University of Technology,Xi’an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Science,Xi’an University of Technology,Xi’an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2013
    },
    "s7zmEScV": {
        "id": "s7zmEScV",
        "title": "The health risk for seafood consumers under future ocean acidification (OA) scenarios: OA alters bioaccumulation of three pollutants in an edible bivalve species through affecting the in vivo metabolism.",
        "abstract": "The current knowledge about the effect of pCO-driven ocean acidification on the bioaccumulation of pollutants in marine species is still scarce, as only limited types of pollutants have been investigated. Therefore, to obtain a better understanding of the effect of ocean acidification on the process of bioaccumulation and subsequent food safety, the accumulation of benzo[a]pyrene (B[a]P), chloramphenicol (CAP), and nitrofurazone (NFZ) in an edible bivalve species, Tegillarca granosa, under present and near-future ocean acidification scenarios was investigated in the present study. The health risks associated with consuming contaminated blood clams were also assessed using target hazard quotient (THQ), lifetime cancer risk (CR), or margin of exposure (MoE). To explain the alterations in bioaccumulation of these pollutants, the expressions of genes encoding corresponding key metabolic proteins were analyzed as well. The results obtained showed that ocean acidification exerted a significant effect on the accumulation of B[a]P, NFZ, and CAP in the clams. After four-week exposure to B[a]P, NFZ, or CAP contaminated seawater acidified with CO at pH 7.8 and 7.4, significantly greater amounts of B[a]P and lower amounts of NFZ and CAP were accumulated in the clams compared to that in the control. Although no non-carcinogenic risk of consuming B[a]P-contaminated blood clams was detected using the THQ values obtained, the CR values obtained indicated a high life-time risk in all groups. In addition, according to the MoE values obtained, the health risks in terms of consuming NFZ- and CAP-contaminated clams were significantly reduced under ocean acidification scenarios but still cannot be ignored, especially for children. The gene expression results showed that the ability of clams to eliminate B[a]P may be significantly constrained, whereas the ability to eliminate NFZ and CAP may be enhanced under ocean acidification scenarios, indicating that the changes in the accumulation of these pollutants may be due to the altered in vivo metabolism.",
        "keywords": [
            "Benzo[a]pyrene",
            "Chloramphenicol",
            "Food safety",
            "Nitrofurazone",
            "Ocean acidification"
        ],
        "authors": [
            {
                "name": "Wenhao Su",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yuan Hu",
                "org": "Zhejiang Mariculture Research Institute, Wenzhou, PR China."
            },
            {
                "name": "Aiying Ke",
                "org": "Zhejiang Mariculture Research Institute, Wenzhou, PR China."
            },
            {
                "name": "Hongxi Wu",
                "org": "Zhejiang Fisheries Technology Extension Station, Hangzhou, PR China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, PR China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2019
    },
    "ny7XtVIs": {
        "id": "ny7XtVIs",
        "title": "Expounding the Feature of \"Philosophy\" in Western Philosophy——Examining from the perspective of ancient Greek philosophy",
        "abstract": "The argument of \"philosophical history is philosophy\" has been reached general consensus.Philosophical history commonly refers to western history of philosophy,which exactly is \"Greek philosophy.\" Ancient Greek philosophy the daughter of city-state,of thinking and of mythology presented the whole western philosophy her features——-rethinking the problems of age by her proceeding with times,her nationality of rational consideration and her human nature of self-deny and self-surmount.These features represent ultimate pursuit of western philosophy for ultimate explanation,embody its spiritual care of putting people first,and illustrate an endless volume of mankind spiritual emancipation.",
        "keywords": [
            "western philosophy",
            "ancient Greek philosophy",
            "characteristics of philosophy"
        ],
        "authors": [
            {
                "name": "Han Qiuhong",
                "org": "School of Politics and Law,Northeast Normal University,Changchun ,China"
            },
            {
                "name": "Shi Wei",
                "org": "School of Politics and Law,Northeast Normal University,Changchun ,China"
            }
        ],
        "venue": "Academic Exchange",
        "year": 2008
    },
    "Q6xxNHWD": {
        "id": "Q6xxNHWD",
        "title": "A Review of Self-expansion Model",
        "abstract": "Self-expansion model proposes that people have the motivation to seek to expand the self(i.e.people seek to enhance their potential self-efficacy by expanding themselves).Self-expansion model emphasizes that self-expansion motivation is a central human motivation.One way in which people expand themselves is through including others in themselves,to some extent,the other's resources,perspectives and identities.Self-expansion model is a conceptual framework that seems as a platform for researching relationships and relationship-linked phenomena.The ideas in self-expansion model renew the view of \"similarity-attraction effect\",\"contact hypothesis\",and related perspectives about close relationships and intergroup relationships.Furthermore,it is helpful to some actual activities such as smoking abstinence.However,self-expansion model itself has not yet been mature.In the future we must take advantage of more other psychological theories for deeper exploration about the model.Meanwhile,we should apply it to the applied fields.",
        "keywords": [
            "self-efficacy",
            "relationship satisfaction",
            "close relationship",
            "self-expansion"
        ],
        "authors": [
            {
                "name": "JIA Feng-Xiang",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2012
    },
    "czwW52xx": {
        "id": "czwW52xx",
        "title": "Changes of TNF-α,TGF-β,and ICAM-1 in the peritoneal lavage fluid from IUD-contraceptive rat models established by non-invasive modeling and laparotomy modeling",
        "abstract": "Objective To analyze the levels of TNF-α,TGF-β and ICAM-1 in peritoneal lavage fluid of IUD contraceptive rat models established by non-invasive modeling and laparotomy modeling.Methods Fifty female SD multiparous rats were randomly assigned into non-invasive,laparotomy,non-invasive control,laparotomy control,and blank control groups,10 rat in each group.Copper-intrauterine device(IUD) was placed into the unilateral uterine of rat in the noninvasive group through vagina-cervix(non-invasive) way and that of invasive group via laparotomy.The rats were also operated in the non-invasive control and laparotomy control groups but without IUD placing.The concentrations of TNF-α,TGF-β,and ICAM-1 in the peritoneal lavage fluid and pathological change of endometrium were examined at 16 days after modeling.Results The TNF-α of non-invasive group,laparotomy group,and laparotomy sham operation group were significantly higher than that in the blank control group(P<0.05).It was highest in the laparotomy group,and was significantly higher than that of the non-invasive group(P<0.01).Compared with the non-invasive control group,the level of TNF-α was significantly higher in the laparotomy group and laparotomy sham operation group(P<0.01 or P<0.05).It was highest in the laparotomy group,and was significantly higher than that of the non-invasive group(P<0.01).The concentrations of ICAM-1 in all groups had no significant differences between each other(P>0.05).There were epithelial defect,congestion,inflammatory cell infiltration,edema and hyperplasia,vascular dilatation and scattered thrombi in the endometrium of non-invasive group and laparotomy group,but were more extensive in the endometrium of IUD placement side in the laparotomy group.Conclusions Compared with the conventional laparotomy IUD placement,the rat models with non-invasive IUD placement show significantly reduced peritoneal irritation,and may better reflect the clinical process of IUD contraception in women.",
        "keywords": [
            "Rat",
            "TNF-α",
            "IUD contraception",
            "Non-invasive IUD placement",
            "IUD placement",
            "TGF-β",
            "ICAM-1",
            "Peritoneal lavage fluid",
            "laparotomy"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Affiliated Hospital of Shandong University of Taditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "LI Zi-fa",
                "org": "Shandong University of Traditional Chinese Medicine,Jinan "
            },
            {
                "name": "YUE Heng-xue",
                "org": "Shandong University of Traditional Chinese Medicine,Jinan "
            },
            {
                "name": "XU Li",
                "org": "Affiliated Provincial Hospital of Shandong University,Jinan "
            }
        ],
        "venue": "Chinese Journal of Comparative Medicine",
        "year": 2013
    },
    "piMuW2G6": {
        "id": "piMuW2G6",
        "title": "A NUMERICAL SIMULATING RESEARCH ON NEOTECTONICS IN THE LOP NUR BASIN",
        "abstract": "Based on analysis of previous researches on neotectonic in Lop Nur Basin,two types of numerical simulation models have been built in this paper: ~N-S trending compression in first stage and NE-SW striking compression in the later stage.Combining with the previous studies,our numerical simulation shows the two main episodes of tectonic evolution occurred in the Lop Nur Basin since Late Cenozoic:(1) the ~N-S trending compression,the extension and rifting from late Oligocene to Early Pleistocene,and(2) the NE-SW striking compression and the shearing deformation since Early Pleistocene.Furthermore,the research shows the stress condition of the geological units is controlled both by lithology and faults;moreover,the low stress appears inside of the basin,and extensional direction is perpendicular to maximum principle compressive stress.The two main faults to the south of the basin are dominated by high shearing stress,whereas the minimal shearing stress distributes both in the basin and to its east.Furthermore,obviously controlled by faults,the displacement decreases from southwest to northeast,indicating the pore fluid migrates from southwest to northeast.This study provides some structural evidences for the research on sylvite forming and oil storage and transformation.",
        "keywords": [
            "neotectonic",
            "Lop Nur Basin",
            "Altyn Tagh fault zone",
            "numerical simulation",
            "Tarim Basin"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China"
            },
            {
                "name": "TIAN Mi",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China;Wuxi Research Institute of Petroleum Geology,SINOPEC,Wuxi ,China"
            },
            {
                "name": "MA Yin-sheng",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China"
            },
            {
                "name": "GONG Ming-quan",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China"
            },
            {
                "name": "DU Jian-jun",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China"
            },
            {
                "name": "LIU Yuan",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciencses,Beijing ,China"
            }
        ],
        "venue": "Journal of Geomechanics",
        "year": 2011
    },
    "dyOjCEmr": {
        "id": "dyOjCEmr",
        "title": "Power-Efficient Routing Mechanism in Sensor Networks based on Node-Density",
        "abstract": "Recent advancement in wireless sensor networks has attracted growing research interest. In this paper, we propose a new routing mechanism Power Efficient Routing based on Sensor Nodes Density (PERD). We use a metric, the nodes density, to help our routing mechanism to select a power conservation route. The PERD can maximize the lifetime of the sensor network by making full use of power available nodes and keeping energy consumed evenly among sensor network with different node density. We use the ns-2 simulator and employ the dynamic source routing (DSR) protocol to evaluate the performance of our routing mechanism and prior proposals for power-aware routing. The simulation result shows that PERD achieves a better performance than the prior mechanisms.",
        "keywords": [
            "ad hoc networks",
            "routing",
            "sensor network",
            "computer networks",
            "power efficiency",
            "dynamic source routing",
            "capacitive sensors",
            "energy efficiency",
            "routing protocols",
            "computer science",
            "wireless sensor network",
            "wireless sensor networks"
        ],
        "authors": [
            {
                "name": "Qing Gao",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Shanping Li",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University, China"
            }
        ],
        "venue": "IMSCCS (2)",
        "year": 2006
    },
    "vZrTs1t6": {
        "id": "vZrTs1t6",
        "title": "Accurate fault location algorithm for series compensated transmission lines",
        "abstract": "Conventional methods of fault location are not suitable for power system with series compensated transmission lines because of MOV protection with nonlinear V-A characteristic. In this paper, it is presented that an accurate fault location algorithm for series compensated transmission lines and the condition of series capacitors and their MOV protection is taken into consideration. The samples of voltages and currents at both ends of the line are taken asynchronous and used to estimate the location of fault. The proposed algorithm is composed from two subroutines that one is for assumed faults in front of the series capacitor and the other is for assumed faults behind the capacitor. Then a comparison of varies sequence results to selecting the correct solution is utilized. The results of computer simulation confirm the high accuracy of the proposed algorithm for different fault resistances and different fault types.",
        "keywords": [
            "Fault location",
            "MOV (Metal-Oxide Varistor)",
            "Series compensated transmission line"
        ],
        "authors": [
            {
                "name": "Yanhua Han",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2002
    },
    "moGRXGK1": {
        "id": "moGRXGK1",
        "title": "The complete mitochondrial genome of Pseudaesopia japonica (Pleuronectiformes: Soleidae).",
        "abstract": "The Pseudaesopia japonica belongs to family Soleidae in order Pleuronectiformes. In this study, the complete mitochondrial genome of P. japonica was determined and described. The mitogenome is 16 790 bp in length and consists of 13 protein-coding genes, 22 tRNAs, two rRNAs, one control region, and a light strand replication origin. The arrangement of this mitogenome is identical to that of the typical teleost. The overall base composition is 28.5%, 25.7%, 30.3%, and 15.5%, for A, T, C, and G, respectively, with a slight bias on A + T content (54.3%). The maximum likelihood phylogeny tree of 22 flatfishes demonstrated that the species from Zebrias and Aesopia firstly formed a sister group, and then clustered in the same clade with P. japonicas. This study is expected to contributing to the systematic evolution of P. japonicas and further phylogenetic relationship of Soleidae and Pleuronectiformes.",
        "keywords": [
            "Mitochondrial genome",
            "Pseudaesopia japonica",
            "phylogenetic relationship"
        ],
        "authors": [
            {
                "name": "Lizhen Si",
                "org": "a Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , PR China and."
            },
            {
                "name": "Li Gong",
                "org": "a Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , PR China and."
            },
            {
                "name": "Wei Shi",
                "org": "a Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , PR China and."
            },
            {
                "name": "Min Yang",
                "org": "a Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , PR China and."
            },
            {
                "name": "Xiaoyu Kong",
                "org": "a Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , PR China and."
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2015
    },
    "PyQ7Sb5J": {
        "id": "PyQ7Sb5J",
        "title": "Design and simulation of solar energy marsh gas tank automatic control system",
        "abstract": "To solve the problem of low gas production rate and low utilization rate in northern regions in winter.A 3D thermal control model based on the theory of percolation is established.In this model,the marsh gas tank and the surrounding soil are seen as an organic whole,it makes the broth thermostatic by analyzing and controlling the soil temperature around the marsh gas tank.A solar energy marsh gas tank control system is designed,using solar energy heat-collecting system to heat the liquid material,and automatically control the temperature of the liquid material fluctuating in the range of ± 2 ℃.It simulates with Proteus and Matlab to verify the correctness of control model and system.",
        "keywords": [
            "system simulation",
            "marsh gas",
            "automatic control",
            "solar energy"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            }
        ],
        "venue": "Transducer and Microsystem Technologies",
        "year": 2011
    },
    "sleZfVXn": {
        "id": "sleZfVXn",
        "title": "An Analysis of Superposed Deformation and Tectonic Stress Fields of the Western Segment of Daba Mountains Foretland",
        "abstract": "The typical superposed deformation developed in the western segment of Daba Mountains foreland,which records distinctly its history of tectonic evolution and is beneficial to research on tectonic regimes conversions.Based on analysis of folded forms croped out in the region,combined with observation of bedding plane and fault slip vector,in this paper,we study in detail on two main periods of Mesozioc tectonic compression stress fields,near SN-trending compression during T3—J1 and near EW-oriented compression during J3—K1.At earlier stage(T3—J1),controlled by near SN-trending compression tectonic stress field,a series of near EW-trending folds formed at Daba Mountains,which may be caused by Indosinian movement.At later stage(J3—K1),the tectonic regime changed to near EW-oriented compression,therefore,earlier near EW-trending folds was deformed strongly,and a series of SN-oriented folds developed.Thus,superposed folds of Daba Mountains foreland formed.At the same time,Fangxian—Zhenba fault zone thrusted intensitily westward.The later deformation of Daba Mountains may resulted from Yanshanian Movement.To study on superposed deformation of Daba Mountains bears on importance for research on blocks interaction in this region,and takes an instructive action on oil and gas of the Northern Sichuan.",
        "keywords": [
            "Daba Mountain foreland",
            "Indosinian movement",
            "Superposed deformation",
            "Tectonic stress fields"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,2)Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "DONG Shuwen",
                "org": ""
            },
            {
                "name": "HU Jianmin",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,2)Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "ZHANG Zhongyi",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,2)Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "LIU Gang",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,2)Chinese Academy of Geological Sciences,Beijing,"
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2007
    },
    "EN05AoQl": {
        "id": "EN05AoQl",
        "title": "Tectonic Deformation Analysis and Paleostress Field Sequence of the Grabens in the Northwestern Jianghan Basin",
        "abstract": "Several grabens were developed within Jianghan Basin and their formation and evolution are essential to accumulation of oil and gas in the basin. With an emphasis on the Yuan'an Graben and Nanzhang Graben in northwestern Jianghan basin and in combination with detailed field observation and measurement of faulting deformation,this study analyzed in detail the tectonic deformation of the northwestern graben zone of Hanjiang basin and established the stress field sequences. Based on the regional structures and superimposed deformation features in this area,the evolution history of the grabens in Jianghan Basin can be divided into four main stages:1) Late Cretaceous to Paleogence,the grabens formed in Jianghan Basin due to an NEE-SWW-trending extension; 2) late Paleogence,the grabens deformed strongly by the E—W-striking tectonic compression; 3) Neogene,controlled by NE—SW-trending extension and NW—SE-striking extension in turn,the grabens were extended again; 4) Late Neogene,dextral-slip activation occurred in the grabens due to NE—SW-striking compression.The establishment of the structural deformation sequence of Hanjiang basin since Late Cretaceous provides structural and geological evidence for probing into the tectonic evolution of Hanjiang basin during the late stage and reformation of oil and gas accumulation.",
        "keywords": [
            "Grabens",
            "Jianghan basin",
            "Late cretaceous",
            "Stress field",
            "Tectonic deformation"
        ],
        "authors": [
            {
                "name": "TIAN Mi",
                "org": " Institute of Geomechanics,CAGS,Beijing,"
            },
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics,CAGS,Beijing,"
            },
            {
                "name": "LI Jianhua",
                "org": " Institute of Geomechanics,CAGS,Beijing,"
            },
            {
                "name": "QU Hongjie",
                "org": " Institute of Geomechanics,CAGS,Beijing,"
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2010
    },
    "ZoyJubdD": {
        "id": "ZoyJubdD",
        "title": "Study on the marine growth effect on the dynamic response of offshore wind turbines",
        "abstract": "Jacket foundation is regarded as a suitable solution for wind turbines in the intermediate water depths ranging from 30 to 80 m. Numerous types of marine fouling organisms may be found on the submerged members of jacket. Marine growth is found to influence loading of offshore structures by increasing tube diameters, drag coefficient, mass and hydrodynamic added mass and structural weight. In this paper, the types and distribution of marine growth are mentioned. We aimed to investigate the effects of marine growth with different thicknesses, densities and hydrodynamic coefficients values on characteristics of an offshore wind turbine with jacket foundation. The eigen analysis shows that the marine growth has a little effect on the first order natural frequencies while it has higher effect on second and third order natural frequencies of the support structure. Thickness and density have a strong effect on hydrodynamic loads. To obtain the properties of marine growth and hydrodynamic coefficients in the design of offshore wind turbines, full-scale measurements are needed.",
        "keywords": [
            "Design load cases",
            " Hydrodynamic loads",
            " Jacket foundation",
            " Marine growth",
            " Offshore wind energy"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": "pohang university of science and technology"
            },
            {
                "name": "hyunchul park",
                "org": "pohang university of science and technology"
            },
            {
                "name": "jaeha baek",
                "org": "pohang university of science and technology"
            },
            {
                "name": "changwan kim",
                "org": "konkuk university"
            },
            {
                "name": "youngchan kim",
                "org": "pohang university of science and technology"
            },
            {
                "name": "hyunkyoung shin",
                "org": "university of ulsan"
            }
        ],
        "venue": "International Journal of Precision Engineering and Manufacturing",
        "year": 2012
    },
    "TwgLlxfN": {
        "id": "TwgLlxfN",
        "title": "Design and VLSI Implementation of an Asynchronous Microprocessor Based on Transport Triggered Architecture",
        "abstract": "The design of an asynchronous pipelined microprocessor based on transport triggered architecture is introduced.The distributed control in the asynchronous TTA microprocessor,the data dependence might give rise to a wrong result of the executed program.A data source select scheme is proposed to guarantee instructions running correctly on the asynchronous TTA microprocessor.The micro-architecture of the proposed asynchronous processor is presented,and an asynchronous microprocessor is implemented in an 180nm technology.The experimental results show that the implemented asynchronous microprocessor can run correctly,and the asynchronous circuit style can offer a low power solution for future microprocessor design.The power dissipation of asynchronous TTA core takes only about 40% of the synchronous equivalent.",
        "keywords": [
            "low power",
            "asynchronous circuit",
            "VLSI design",
            "transport triggered architecture"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "CHEN Fang-yuan",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "WANG Zhi-ying",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "REN Hong-guang",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "SU Bo",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "WANG You-rui",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            },
            {
                "name": "LU Hong-yi",
                "org": "School of Computer,National University of Defense Technology,Changsha,Hunan ,China"
            }
        ],
        "venue": "Acta Electronica Sinica",
        "year": 2011
    },
    "PohImS1q": {
        "id": "PohImS1q",
        "title": "Transient thermal effect of semi-insulating GaAs photoconductive switch",
        "abstract": "Results of experiments of the 4 mm gap semi-insulating(SI) GaAs photoconductive switch triggered by 1064 nm,1. 0 mJ pulse laser showed the nonlinear mode when the bias field was 3800 V. Under the same bias electric field and trigger light energy conditions,the switch outputs stably nonlinear electrical pulses,and the switch surface injury mark is caused by filamentation after 1500 times triggering. Analysis shows that under given conditions of trigger energy and electric field, two transient thermal effects occur in the switch chip,namely the thermal relaxation and photoactivated charge domain- phonon drag,respectively. Thermal relaxation time is shortened to the order of picoseconds or subpicoseconds,thermal relaxation process leads to the thermal conduction relaxation. When photoactivated charge domain moves at 107 cm /s speed from cathode to anode,switch chip transient temperature makes relaxation oscillations owing to these effects,and the rapid increase of temperature in the chip is constrained. Photoactivated charge domain-phonon drag effect transmits in the direction of the dislocation movement,the temperature in mobile region increases when the flow of thermal energy carried by the phonons was concentrated in the movement plane,the injury of filamentation is produced by superposition and cumulation of mobile tracks.",
        "keywords": [
            "Filamentation",
            "Photoactivated charge domain-phonon drag effect",
            "SI-GaAs photoconductive switch",
            "Thermal relaxation effect"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "Department of Applied Physics,Xi’an University of Technology,Xi’an ,China"
            },
            {
                "name": "Xiangrong Ma",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Xue Hong",
                "org": "Department of Applied Physics,Xi’an University of Technology,Xi’an ,China"
            }
        ],
        "venue": "Acta Physica Sinica",
        "year": 2010
    },
    "PXL5XSyo": {
        "id": "PXL5XSyo",
        "title": "Effect of Shenmai injection on expression of hypoxia-inducible factor 1-α in perihematomal brain tissue of hematoma in rats with intracerebral hemorrhage",
        "abstract": "Objective To study the effect of Shenmai injection on the expression of hy-poxia-inducible factor 1-α(HIF1-α)in the perihematomal area in rats with intracerebral hemor-rhage.Methods The 50 rats were randomly divided into 4 groups as follows: normal,false op-eration,model and Shenmai groups,and the rats in the model and Shenmai groups were divide into four periods respectively of 1,3,5 and 7 day after operation.The intracerebral hemorrhage models were induced by injecting Collagenase type Ⅶ stereotaxically;the expression of hypoxia-inducible factor 1-α in the perihematomal area was measured with immunohistochem,and the effect of Shenmai injection also was measured.Results Compared with modeling groups,the hematoma in Shenmai group was absorbed;there were no expression of HIF1-α in normal and false operation groups;and the expressions of HIF1-α in the perihematomal area in model group was increased at 1st day,got to a peak at 3rd day,decreased gradually at 5st day,and kept a few at 7th day(P<0.01).Conclusions Shenmai injection is effective to protect the rats af-ter ICH,promote absorption of hematoma and inhibit the expression of HIF1-α.",
        "keywords": [
            "Radix ophiopogonis",
            "SD rats",
            "Shenmai injection",
            "ICH",
            "ginseug",
            "HIF1-α"
        ],
        "authors": [
            {
                "name": "HUANG Ren-fa",
                "org": "First Affiliated Hospital,Guangxi college of traditional Chinese medicine,Nanning,Guangxi ,China"
            },
            {
                "name": "HE Ze-yun",
                "org": "First Affiliated Hospital,Guangxi college of traditional Chinese medicine,Nanning,Guangxi ,China"
            },
            {
                "name": "LIU Jing-song",
                "org": "First Affiliated Hospital,Guangxi college of traditional Chinese medicine,Nanning,Guangxi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "First Affiliated Hospital,Guangxi college of traditional Chinese medicine,Nanning,Guangxi ,China"
            },
            {
                "name": "WU Jin-yu",
                "org": "First Affiliated Hospital,Guangxi college of traditional Chinese medicine,Nanning,Guangxi ,China"
            }
        ],
        "venue": "Journal of Traditional Chinese Medicine University of Hunan",
        "year": 2008
    },
    "tUwM0hA4": {
        "id": "tUwM0hA4",
        "title": "Optimization and characterization of the guest-host polyetherketone polymer films for application in integrated optical devices",
        "abstract": "",
        "keywords": [
            "optical waveguide",
            "nonlinear optics",
            "second order",
            "thin film"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            },
            {
                "name": "Qiwei Pan",
                "org": ""
            },
            {
                "name": "Zhihui Qin",
                "org": ""
            },
            {
                "name": "Qintian GU",
                "org": ""
            },
            {
                "name": "Dong Xu",
                "org": ""
            },
            {
                "name": "Jinzhong Yu",
                "org": ""
            }
        ],
        "venue": "Journal of Physics D-applied Physics",
        "year": 2002
    },
    "GsQnhKlb": {
        "id": "GsQnhKlb",
        "title": "Foreign University Practice Teaching Mode and Reference",
        "abstract": "The practice teaching have the incomparable superiority relative to the theory teaching in the aspects of practical ability cultivation of talents,innovation ability and learning ability,the article attempts to summarize the successful experience characteristics of foreign university practice teaching,then according to the current situation of our weakening practice teaching,drawing lessons from the successful practice teaching mode of foreign university and reflect the Chinese teaching practice;the article put forward to reform the innovation practice teaching mode and construct the idea of the value orientation of happiness,and construct the practice teaching mode by taking the cultivation of students' autonomous learning ability as the core.",
        "keywords": [
            "foreign university",
            "practical teaching",
            "mode"
        ],
        "authors": [
            {
                "name": "CHEN Yuan-yuan",
                "org": "College of Education,Huaibei Normal University,Huaibei "
            },
            {
                "name": "SHI Wei",
                "org": "Department of science and Technology,Fuyang Normal College,Fuyang ,China"
            }
        ],
        "venue": "Meitan Higher Education",
        "year": 2012
    },
    "gl85DMfo": {
        "id": "gl85DMfo",
        "title": "Confirming to the 14 symptom units of perspiration",
        "abstract": "7 384 original descriptions on perspiration were withdrew from the medical record database of the past dynasties.It was pointed out that the combination of 14 symptom units of perspiration and 3 limiting factors can express the original descriptions.Compared with the authority works of Chinese and western medicine,it was found there are several symptom units and limiting factors of perspiration did not been taken seriously.",
        "keywords": [
            "diagnostics of Chinese medicine",
            "symptom unit",
            "perspiration"
        ],
        "authors": [
            {
                "name": "XU Li",
                "org": "Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "TIAN xin",
                "org": "Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan ,China"
            },
            {
                "name": "WANG Yi-guo",
                "org": "Institute of Basic Research in Clinical Medicine of China Academy of Chinese Medical Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Qi-ming",
                "org": "Institute of Basic Research in Clinical Medicine of China Academy of Chinese Medical Sciences,Beijing ,China"
            }
        ],
        "venue": "Shandong Journal of Traditional Chinese Medicine",
        "year": 2010
    },
    "FJBcZG6t": {
        "id": "FJBcZG6t",
        "title": "Restoration of terahertz continuous wave image obtained by continuous scan mode with large time constant.",
        "abstract": "Abstract-continuous scan mode offers a relatively higher data achievement rate than the step scan mode, so it is often used in continuous-wave terahertz imaging to improve the imaging efficiency. The large time constant of lock-in amplifiers also provides good noise attenuation; however, it might bring motion blur to some extent in continuous scan mode. To cope with the problem, an imaging restoration method, which identifies the motion-point spread function of the motion blur, was proposed. A modified spatial filter was used to restore the blurred image. The image quality is better than that obtained by a conventional Wiener filter evaluated by a modified no-reference motion blur metric.",
        "keywords": [
            "digital image processing",
            "terahertz imaging"
        ],
        "authors": [
            {
                "name": "Xiao Lou",
                "org": ""
            },
            {
                "name": "Lei Hou",
                "org": ""
            },
            {
                "name": "Gaoyuan Guo",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Applied optics",
        "year": 2014
    },
    "sj29aSGn": {
        "id": "sj29aSGn",
        "title": "The complete mitochondrial genome sequence of Gerres filamentosus (Perciformes: Gerridae)",
        "abstract": "AbstractThe complete mitochondrial genome of Gerres filamentosus was sequenced by high throughput sequencing method. Length of this genome is 16,795 bp, containing 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. ND6 and eight tRNA genes are encoded by L-strand, and others are encoded by H-strand, which is similar to those in most vertebrates. Phylogenetic tree based on 13 protein-coding genes shows that the clade of G. filamentosus is closely clustered with that of Gerres oyena, and families Caproidae and Ephippidae have the closest relationship to Gerridae, comparing with Sillaginidae",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Baosheng Wu",
                "org": " CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China"
            },
            {
                "name": "Hui Yu",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "RT9WCLSJ": {
        "id": "RT9WCLSJ",
        "title": "Study on the protection of lightning intruding waves in 750 kV GIL-GIS system",
        "abstract": "On the basis of one 750 kV substation, the 750 kV GIL-GIS system that takes gas insulated line (GIL) as the ingoing line of GIS is established in this paper. Through two types of lightning stroke, lightning stroke on the top of a tower and shielding failure, considering the effects of ground angle and ground resistance, the lightning over-voltages on disconnecting switch (DS), circuit breaker (CB), current transformer (CT) and transformer are calculated by EMTP when lightning waves intrude into the 750kV GIL-GIS system. According to the over-voltage values on the above equipment, the protective scheme adopting mental oxide arrestor (MOA) are correspondingly presented. The effects of lightning protection are compared when the ingoing line of GIS is GIL and overhead line (OHL) respectively, and the results are analyzed also.",
        "keywords": [
            "Gas-insulated transmission lines",
            "Lightning shielding failure",
            "Lightning striking the tower top",
            "Mental oxide arrestor",
            "Overhead lines",
            "Protection of lightning intruding waves"
        ],
        "authors": [
            {
                "name": "Liangjin Chen",
                "org": "Zhejiang Electric Power Test and Research Institute(Zhejiang Electric Power Test and Research Institute),Hangzhou,China"
            },
            {
                "name": "Wenyi Li",
                "org": "Zhejiang Electric Power Test and Research Institute(Zhejiang Electric Power Test and Research Institute),Hangzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2005
    },
    "M40fhDRV": {
        "id": "M40fhDRV",
        "title": "Analysis of Damage Induced by Repetition-Frequency Optical Pulse in Semi-insulating GaAs PCSS′s Material",
        "abstract": "Based on the damage test of GaAs photoconductive semiconductor switch(PCSS) triggered by nanosecond laser pulse with 1 064 nm wavelength at different repetition frequencies,the main reasons of optical injury in switch chip material at different repetition frequencies were analyzed by comparing the damage threshold of materical and observing the change of resistivity values when the switch was on/off,and the damage mechanism was discussed.Experiment results show that the damage threshold of semi-conductor material irradiated by repetition-frequency laser is lower than by single impulse.And the input laser with different repetition frequencies may cause different temperature rising speeds on the surface of material.It is pointed out that when the repetition frequency is less than 1 kHz,the temperature accumulation effect in the material dose not perform significantly.The reason of the damage induced by low-repetition frequency laser should be micro-damage accumulation.There is no significant relationship between optical injury in material and repetition rate.When the pulse laser is at high repetition frequency,the temperature rising rate in the laser irradiation area gets faster,and the optical damage is mostly caused by thermal accumulation.",
        "keywords": [
            "repetition frequency",
            "semi-insulating GaAs",
            "micro-damage accumulation",
            "resistivity",
            "damage threshold"
        ],
        "authors": [
            {
                "name": "Xiang Shan",
                "org": "College of Science,Air Force Engineering University,Xi′an ,China"
            },
            {
                "name": "Dai Huiying",
                "org": "College of Science,Air Force Engineering University,Xi′an ,China"
            },
            {
                "name": "Shi Wei",
                "org": "College of Science,Xi′an University of Technology,Xi′an ,China"
            }
        ],
        "venue": "Semiconductor Technology",
        "year": 2012
    },
    "vq5EMaoM": {
        "id": "vq5EMaoM",
        "title": "Rearrangement of mitochondrial genome in fishes]",
        "abstract": "Generally, the mitochondrial genome is characterized by the property of highly conserved organization. After comparing the 1,255 fish complete mitogenome sequences deposited in GenBank (as of Nov. 3, 2013), approximately 52 complete mitogenomes are found to have been rearranged. Of these species, three types of rearrangement-shuffling, translocation, and inversion-have been found. Further analysis shows that the sites of the rearrangements occur frequently in WANCY cluster, IQM cluster, ND6 gene, control region (D-loop) and its adjacent genes. Based on the four models that explain the gene rearrangements commonly adopted by scientists, we attempted to infer the possible mechanisms for the three types of gene rearrangement as well as the application of gene rearrangement in phylogenetic studies.Abstract available from the publisher.",
        "keywords": [
            "phylogenesis",
            "gene rearrangement",
            "Translocation",
            "translocation",
            "Gene rearrangement",
            "inversion",
            "Shuffling",
            "Inversion",
            "mtdna",
            "Phylogenesis",
            "tDNA",
            "shuffling"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Li-Zhen Si",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Dong wu xue yan jiu = Zoological research / \"Dong wu xue yan jiu\" bian ji wei yuan hui bian ji",
        "year": 2013
    },
    "NfrXQgFy": {
        "id": "NfrXQgFy",
        "title": "Determination of the macroscopic optical properties for the NAEC/PEK-c guest–host polymer films",
        "abstract": "The polyetherketone (PEK-c) guest–host polymer films doped with (4′-nitro)-3-azo-9-ethyl-carbazole (NAEC) were prepared. The films were poled by corona-onset poling at elevated temperature (COPET). The orientational order parameter of the chromophores NAEC in poled polymer film was determined by measuring the absorption spectra of the films before and after being poled. By using the two-level model, the measured dispersion of the refractive index of the polymer film, and the dispersion of the first hyperpolarizability of chromophore NAEC, the dispersion of the macroscopic second-order nonlinear optical (NLO) and linear electro-optic (EO) coefficients was evaluated for the NAEC/PEK-c guest–host polymer film.",
        "keywords": [
            "polymer film",
            "optical properties",
            "poling",
            "absorption spectrum",
            "nonlinear optics",
            "spectrum",
            "second order",
            "absorption spectra",
            "refractive index"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Feng Li",
                "org": "Department of Chemistry, Jilin University, Changchun 130023, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hongzheng Wei",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            }
        ],
        "venue": "Optics and Lasers in Engineering",
        "year": 2001
    },
    "54are4QN": {
        "id": "54are4QN",
        "title": "Silicon-on-insulator based 2 × 2 multimode interference coupler with large tolerance",
        "abstract": "We demonstrate a type of 2 × 2 multimode interference 3 dB coupler based on silicon-on-insulator. The fabrication tolerance was investigated by the effective index method and the guide mode method. The devices with different lengths were fabricated and near-field output images were obtained. Tolerances to width, length and etch depth are 2, 200 and 2 μm, respectively. The devices show a uniform power distribution.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "JinZhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhongli Liu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2001
    },
    "22woRmgW": {
        "id": "22woRmgW",
        "title": "Research on Noetectonic of the Lop Nur Basin Based on Sandbox Experiments",
        "abstract": "Based on analysis of existing data of the Lop Nur basin,Neotectonic in this area have been modeled primarily by sandbox experiments. In this paper,two kinds of models have been carried out,and experimental result shows,controlled by nearly S-N compression,the Altyn Tagh Shan and Kuruktag thrusted strongly toward the Lop Nur basin at the same time,and many faults and fault-related folds developed in the S-N edges of the Lop Nur basin. The right-handed slip reverse faults have grown in the Kuruktag,and the left-handed slip reverse faults have developed in the Altyn Tagh Shan,by which the Lop Nur basin have been controlled,and resulted in the eastern Tarim block escaped toward west and the Lop Nur basin extended inside. In addition,the reverse faults developed in the cover of two edges of the Lop Nur basin extend according with its boundary faults. Our research also shows that deformation of the cover are controlled by the basement which is not plastic but rigid. The result of experiment has validated tectonic deformation of the Lop Nur basin at present,and provided a valuable reference for the research on mineralization in this area.",
        "keywords": [
            "neotectonic",
            "Altyn Tagh fault zone",
            "Lop Nur basin",
            "Tarim basin",
            "sandbox experiment"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,CAGS,Beijing ,China"
            },
            {
                "name": "LIU Chenglin",
                "org": "Institute of Mineral Resources,CAGS,Beijing ,China"
            },
            {
                "name": "YANG Haijun",
                "org": "Tarim Oilfield Company,PetroChina,Korla ,Xinjiang,China"
            },
            {
                "name": "MA Yinsheng",
                "org": "Institute of Geomechanics,CAGS,Beijing ,China"
            },
            {
                "name": "XIE Guoai",
                "org": "Department of Geology,Nanjing University,Nanjing ,Jiangsu,China"
            },
            {
                "name": "GU Yuanqiao",
                "org": "Tarim Oilfield Company,PetroChina,Korla ,Xinjiang,China"
            },
            {
                "name": "GONG Mingquan",
                "org": "Institute of Geomechanics,CAGS,Beijing ,China"
            },
            {
                "name": "DU Jianjun",
                "org": "Institute of Geomechanics,CAGS,Beijing ,China"
            },
            {
                "name": "SHI Jun",
                "org": "Inner Mongolia No.5 Geology Minerals Exploration and Development Institute,Baotou ,Inner Mongolia,China"
            }
        ],
        "venue": "Geotectonica Et Metallogenia",
        "year": 2009
    },
    "DZodD123": {
        "id": "DZodD123",
        "title": "Clinical analysis of 63 cases of ischemic colitis",
        "abstract": "To summarize the clinical features,endoscopic manifestations,diagnosis and treatment of ischemic colitis(IC). We retrospectively analyzed the clinical symptoms,suspected etiological factors,signs and endoscopic results of 63 patients. IC was likely to occur in patients over 50 years old(87.3%,55/63),with main clinical symptoms as acute lower abdominal pain and hematochezia.Hypertension,coronary heart disease and diabetes might be the main etiological factors.All the cases were classified endoscopically as non-gangrenous IC.The dividing line between lesion and the normal intestine segments was clear under endoscope.The manifestations of the lesion intestine segment included mucosal erythema,edema,submucosal erythema,punctiform erosion,and superficial ulcer which represented as longitudinal or irregular shape.Fifty-one(52/59,88.1%) of the 59 patients reexamined by colonoscopy two weeks later completely recovered.Five patients(5/59,8.5%) obviously recovered,still with mucosal erythema,mild hyperemia and edema.Focal colonic stricture occurred in 2 patients(3.1%).Four patients did not undergo reexamination because of symptomatic relief after the first colonoscopy.No death ever occurred. Acute lower abdominal pain and hematochezia serve as alarming signs of possible IC for elderly patients who then should receive timely colonoscopy which is proved to be an essential approach for diagnosing and evaluating the extent and degree of disease and predicting of prognosis.",
        "keywords": [
            "Clinical feature",
            "Ischemic colitis",
            "Colonoscope"
        ],
        "authors": [
            {
                "name": "CHAO Qi-chang",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "XI Wei-dong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SUN Xiao-bin",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "NONG Chun-yan",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            }
        ],
        "venue": "Practical Journal of Clinical Medicine",
        "year": 2012
    },
    "caRVXIhE": {
        "id": "caRVXIhE",
        "title": "Development of Cerebral Palsy-Gross Motor Function Questionnaire",
        "abstract": "Objective To work out the Cerebral Palsy-Gross Motor Function Questionnaire(CP-GMFQ) and evaluate the reliability,validity and responsiveness of CP-GMFQ.Methods 160 children with cerebral palsy(CP)(97 males and 63 females;average age: 47.7±20.1 months,range: 18～90 months) were involved.The first 27 children received second assessment to assess test-retest reliability with a interval of 7 to 18 days.Criterion-related validity was evaluated by comparing CP-GMFQ scores with Gross Motor Function Classification System(GMFCS) levels and scores of Gross Motor Function Measure(GMFM).21 children were randomly selected for responsiveness analysis by effect size.After a interval of 3 to 7 months the re-assessment GMFQ and GMFM were tested.30 children were randomly selected for comparative testing time of GMFQ and GMFM.Results GMFQ had excellent test-retest reliability(ICC=0.9940);criterion-related validity was excellent between GMFQ scores and GMFCS levels and GMFM scores(r=0.77～0.92).Effect size of GMFQ(0.34) between GMFM88 and GMFM66,testing time of GMFQ(average 4.7±1.6 min) were significantly less than testing time of GMFM(average 17.7±4.6 min)(P<0.001).Conclusion The reliability,validity and responsiveness of GMFQ are satisfying.The gross motor functions of children with cerebral palsy could be easy and reasonably measured by GMFQ.",
        "keywords": [
            "questionnaire",
            "cerebral palsy",
            "gross motor",
            "function"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ",et al.The Child Rehabilitation Department,Children's Hospital of Fudan University-Hua Jing Community Health Center,Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": ",et al.The Child Rehabilitation Department,Children's Hospital of Fudan University-Hua Jing Community Health Center,Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": ",et al.The Child Rehabilitation Department,Children's Hospital of Fudan University-Hua Jing Community Health Center,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Rehabilitation Theory and Practice",
        "year": 2008
    },
    "0LJiwdYW": {
        "id": "0LJiwdYW",
        "title": "License Plate Location Based on Edge Detection and Morphological Image Processing",
        "abstract": "Vehicle license plate recognition(LPR) is one of the key technologies of intelligent traffic management.The vehicle license plate recognition technology mainly includes:the accurate location of license plate,the division of characters on vehicle plate and the character recognition.In this paper,through analysing the problem above,we find a method of vehicle license plate location based on edge detection and morphological image processing.Through the edge detection of the sample image we get,and a series of morphological image processing,we can get a preliminary location image.According to the times of grayscale changes in horizontal direction,we can get an accurate location image.In this paper,we use some images to emulate the process of location,and the results show the method is feasible and effective.",
        "keywords": [
            "digital image processing",
            "edge detection",
            "license plate location",
            "morphological image processing"
        ],
        "authors": [
            {
                "name": "DONG Ran",
                "org": "College of Information Engineering,Taiyuan University of Technology,Taiyuan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "College of Information Engineering,Taiyuan University of Technology,Taiyuan ,China"
            }
        ],
        "venue": "Mechanical Engineering & Automation",
        "year": 2010
    },
    "grpq9TzS": {
        "id": "grpq9TzS",
        "title": "Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors",
        "abstract": "In our efforts to develop novel dual c-Met/VEGFR-2 inhibitors as potential anticancer agents, a series of 2-substituted-4-(2-fluorophenoxy) pyridine derivatives bearing pyrazolone scaffold were designed and synthesized. The cell proliferation assay in vitro demonstrated that most target compounds had inhibition potency on both c-Met and VEGFR-2, especially compound 9h, 12b and 12d. Based on the further enzyme assay in vitro, compound 12d was considered as the most promising one, the IC50 values of which were 0.11 mu M and 0.19 mu M for c-Met and VEGFR-2, respectively. Further molecular docking studies suggested a common mode of interaction at the ATP-binding site of c-Met and VEGFR-2, indicating that 12d was a potential compound for cancer therapy deserving further study. (C) 2017 Elsevier Inc. All rights reserved.",
        "keywords": [
            "c-Met",
            "VEGFR-2",
            "2-Substituted-4-(2-fluorophenoxy) pyridine",
            "Pyrazolone",
            "Triazole"
        ],
        "authors": [
            {
                "name": "Weijie Gu",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Yuxuan Dai",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hao Qiang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Chen Liao",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Fangnuo Zhao",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenlong Huang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOORGANIC CHEMISTRY",
        "year": 2017
    },
    "WjExaBEs": {
        "id": "WjExaBEs",
        "title": "The Preview of Cognitive Development of Avoidant Personality and its Diagnostic Criteria",
        "abstract": "Avoidant personality disorder is a major personality disorder type that closely linked to anxiety.The main content of this paper is the historical researches and diagnostic criteria.But the datum is too obsolete,and needs to do cross-cultural researches.",
        "keywords": [
            "anxious",
            "cross-cultural researches",
            "diagnostic criteria",
            "Negative psychosis",
            "horror"
        ],
        "authors": [
            {
                "name": "BING Shengnan",
                "org": "Culture & Social Development School,Southwest University,Chongqing "
            },
            {
                "name": "SHI Wei",
                "org": "Culture & Social Development School,Southwest University,Chongqing "
            }
        ],
        "venue": "The Guide of Science & Education",
        "year": 2011
    },
    "VJz4yrJK": {
        "id": "VJz4yrJK",
        "title": "Amiloride reduces proteinuria and inhibits podocyte uPAR in the 5/6 nephrectomy rats]",
        "abstract": "To observe the effect of amiloride on the proteinuria of the 5/6 nephrectomy rats.To establish the 5/6 nephrectomy rats model and divide the experiment into 3 groups, sham operated group(Sham), 5/6 nephrectomy model group(NTX) and 5/6 nephrectomy with amiloride-treated group (NTX+amiloride, n=15). The concentration of protein and mRNA of uPAR and the change of podocytes motility were detected by coomassiebluestaining, immunofluorence method and real-time PCR.At second week, compared with Control group, the 24 h urine protein of NTX group was significantly increased (47.50 ± 28.05 mg vs 14.28 ± 3.8 mg, P = 0.023). There was no statistical significance in 24-hour urine protein between NTX+amiloride group and NTX group (51.56 ± 21.03 mg vs 47.50 ± 28.05 mg, P = 0.748). The same situation was also observed at the time point of 12 week, comparing with NTX group, 24-hour urine protein decreased in Sham group (188.31 ± 29.82 mg vs 21.32 ± 8.59 mg, P = 0.000) and NTX+amiloride group (188.31 ± 29.82 mg vs 121.37 ± 31.14 mg, P=0.000), with statistical significance when comparing with Sham group, the expression of uPAR mRNA in NTX group was significantly increased (9.74 ± 1.44 vs 1.01 ± 0.13, P = 0.000). In contrast, the expression of uPAR mRNA in NTX rats treated with amiloride was significantly lower than in NTX group (9.74 ± 1.44 vs 5.01 ± 1.36, P = 0.000).Amiloride can reduce the proteinuria of the 5/6 nephrectomy rats model of transient proteinuria by inhibiting the induction of uPAR expression.",
        "keywords": [],
        "authors": [
            {
                "name": "Chaosheng He",
                "org": "Southern Medical University, Guangzhou 510515, China; Department of Nephrology, Guangdong General Hospital, Guangzhou 510080, China; Guangdong Academy of Medical Sciences, Guangzhou 510080, China. E-mail: hcs_gz@139.com."
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Shaoting Xie",
                "org": ""
            },
            {
                "name": "Yun Yang",
                "org": ""
            },
            {
                "name": "Juan Ma",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2014
    },
    "mbO07qqY": {
        "id": "mbO07qqY",
        "title": "The complete mitochondrial genome sequence of Cynoglossus sinicus (Pleuronectiformes: Cynoglossidae).",
        "abstract": "Abstract Cynoglossidae (tongue soles) mitogenomes have been found to be translocated in their control region and a tRNA gene inversed, but no gene rearrangement in Soleidae, the closest family to Cynoglossidae, has been detected. In order to explore whether or not mitogenomes of tongue soles bear other gene-rearrangement types, we determined another tongue sole mitogenome of Cynoglossus sinicus. The total length of this mitogenome is 16,478 bp, and the tRNA-Gln gene is translocated from the light strand (L-strand) to the heavy strand (H-strand), accompanied by shuffling of tRNA-Gln, Ile and Met genes with a 143 bp intergenic spacer between tRNA-Gln and Ile. The control region (CR) might translocate to the position between the ND1 and the tRNA-Gln genes. The order of the rest genes is identical to that of the typical fish.",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China."
            },
            {
                "name": "Jin-Xia Jiang",
                "org": ""
            },
            {
                "name": "Xian-Guang Miao",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2014
    },
    "EhiiqkeI": {
        "id": "EhiiqkeI",
        "title": "The complete mitochondrial genome of Pseudorhombus dupliocellatus (Pleuronectiformes: Paralichthyidae).",
        "abstract": "The Pseudorhombus dupliocellatus belongs to family Paralichthyidae of Pleuronectiformes. In this study, the complete mitochondrial genome of P. dupliocellatus is determined and described. The mitogenome is 16 621 bp in length and consists of 13 protein-coding genes, 22 tRNAs, 2 rRNAs, a control region, and a L-strand replication origin. The arrangement of the mitogenome is identical to that of the typical teleost. The overall base composition is 26.9%, 25.3%, 31.0%, and 16.8% for A, T, C, and G, respectively, with a slight bias on A+T content (52.2%). The phylogenetic tree of 13 species all in Pleuronectiformes demonstrated that P. dupliocellatus, as well as the other Paralichthyidae fishes containing Paralichthys olivaceus and Pseudorhombus cinnamoneus, clustered in a Glade and had a closer relationship with Pleuronectidae species than Bothidae ones. This study is expected to contributing to the systematic evolution of Paralichthyidae and further Pleuronectiformes.",
        "keywords": [
            "Mitochondrial genome",
            "Pseudorhombus dupliocellatus",
            "phylogenetic relationship"
        ],
        "authors": [
            {
                "name": "l z si",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China"
            },
            {
                "name": "lei gong",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China"
            },
            {
                "name": "wei shi",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China"
            },
            {
                "name": "ming yang",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China"
            },
            {
                "name": "x y kong",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China"
            }
        ],
        "venue": "MITOCHONDRIAL DNA PART A",
        "year": 2017
    },
    "ltrxmXiW": {
        "id": "ltrxmXiW",
        "title": "Endoscopic and pathological features of gastrointestinal mesenchymal tumor from 53 clinical cases",
        "abstract": "Objective To make a correct diagnosis of gastrointestinal mesenchymal tumor by observing the endoscopic and pathological features from the 53 clinical cases. Methods The data about the endoscopy,pathology and immunohistochemical index including CD117,CD34,SMA and Desmin were collected.The clinical and endoscopic characteristics,pathological and immunohistochemical features were analyzed. Results There were different imaging features between gastrointestinal stromal tumors and leiomyoma.Most of the stromal tumors were located in the stomach and leiomyoma in the esophagus,the ratios were 64.71% and 68.42%,respectively.CD117 and CD34 were diffusely and strongly expressed in stromal tumors,but SMA and Desmin were focal expressed correspondingly with lower rates.Stromal tumors located in small intestine showed higher rate in SMA and lower rate in CD34.On the contrary,there were diffuse and strong expressions of SMA and Desmin in gastrointestinal leiomyoma,and the positive rates of CD117 and CD34 in leiomyoma were significantly lower than those in stromal tumors.According to correlation analysis,the negative expression of Desmin contributed to the diagnosis of stromal tumors and the negative expressions of CD117 and CD34 contributed to the diagnosis of leiomyoma. Conclusion The united immunohistochemical index detection of CD117,CD34,SMA and Desmin combined with endoscopic ultrasonography could enhance the accuracy in differentiation diagnosis between gastrointestinal stromal tumors and leiomyoma.",
        "keywords": [
            "Gastrointestinal stromal tumors",
            "Leiomyoma",
            "Gastrointestinal mesenchymal tumor"
        ],
        "authors": [
            {
                "name": "LI Yu",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "SUN Xiaobin",
                "org": "Department of Pathology,the Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "TANG Yan",
                "org": "Department of Pathology,the Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "LIU Shaohuai",
                "org": "Department of Pathology,the Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "XI Weidong",
                "org": "Department of Gastroenterology"
            },
            {
                "name": "CHAO Qichang",
                "org": "Department of Gastroenterology"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2010
    },
    "yxkMKRhb": {
        "id": "yxkMKRhb",
        "title": "Identification of chemicals in the vapor phase by directly measuring absorption spectra through frequency-tuning a monochromatic THz source",
        "abstract": "",
        "keywords": [
            "chemicals",
            "fingerprint recognition",
            "chemical species",
            "absorption spectra",
            "terahertz radiation",
            "absorption",
            "spectrum",
            "molecules"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": "lehigh university"
            },
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            }
        ],
        "venue": "",
        "year": 2004
    },
    "JL1Wg0O7": {
        "id": "JL1Wg0O7",
        "title": "An Earthquake Ground Motion Database System with Automatic Record Selection Methods",
        "abstract": "With many earthquakes happening in recent years,the seismic performance of building structures is more and more important.How to select earthquake ground motion records for testing buildings is becoming much more necessary.Although the occident has set up some earthquake ground motion database systems for researches of seismic performance of building structures,these database systems are not able to cover characteristics of earthquake ground motions of our country,nor offer record election methods meeting requirements of our engineering designs,let alone the automatic record selection method.Therefore,it is much necessary to develop an earthquake ground motion database system and scientific and reasonable selection methods of our country immediately.This paper presents an earthquake ground motion database system,which collects a lot of earthquake ground motion records.And the system supports two kinds of earthquake ground motion record selection methods:the conditional ground motion selection method and the severest ground motion selection method.Many experiments prove that the efficiency and effects of earthquake ground motion record selection methods can both meet users' requirements.",
        "keywords": [
            "skyline",
            "k-dominant",
            "severest ground motion selection method",
            "earthquake ground motion database system",
            "conditional ground motion selection method"
        ],
        "authors": [
            {
                "name": "Xu Yajun",
                "org": "School of Software,Tsinghua University,Beijing ;Tsinghua National Laboratory for Information Science and Technology,Beijing ;Key Laboratory for Information System Security(Tsinghua University"
            },
            {
                "name": "Wang Chaokun",
                "org": "School of Software,Tsinghua University,Beijing ;Tsinghua National Laboratory for Information Science and Technology,Beijing ;Key Laboratory for Information System Security(Tsinghua University"
            },
            {
                "name": "Wei Dongmei",
                "org": "School of Software,Tsinghua University,Beijing ;Tsinghua National Laboratory for Information Science and Technology,Beijing ;Key Laboratory for Information System Security(Tsinghua University"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ;Key Laboratory of Civil Engineering Safety and Durability of China(Tsinghua University"
            },
            {
                "name": "Pan Peng",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ;Key Laboratory of Civil Engineering Safety and Durability of China(Tsinghua University"
            }
        ],
        "venue": "Journal of Computer Research and Development",
        "year": 2011
    },
    "U44I17ee": {
        "id": "U44I17ee",
        "title": "Calculation and Analysis of a Switchgear Fault Caused by Lightning Strike on 220kV Transmission Lines",
        "abstract": "Flashovers or even explosions of switchgears fixed on substations and power plant at the voltage rank of 220 kV or below,which were caused by lightning intrusive waves,have taken place frequently in east China in recent years.In July 2007,this kind of event occurred because of lightning strike on the 220 kV transmission line,which generated the circuit breaker flashover and current transformer dielectric breakdown.This paper simulates the accident considering the running condition,and obtains the lightning over-voltages by the software EMTP.According to the over-vohage values,the reasons of the accident are analysed,and some protection methods from over-voltage due to lightning intrusive wave are presented by installing MOAs at both ends of the 220 kV transmission lines.",
        "keywords": [
            "lightning intrusive wave",
            "flashover",
            "over-voltage",
            "breakdown",
            "circuit breaker"
        ],
        "authors": [
            {
                "name": "TAO Rong-ming",
                "org": ""
            },
            {
                "name": "CHEN Liang-jin",
                "org": "Zhejiang Electric Power Test and Research Institute,Hangzhou ,China"
            },
            {
                "name": "GAO Yuan",
                "org": "School of Electrical Engineering,Xi'an Jiaotong University,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering,Xi'an Jiaotong University,Xi'an ,China"
            }
        ],
        "venue": "High Voltage Apparatus",
        "year": 2008
    },
    "LrycOAMC": {
        "id": "LrycOAMC",
        "title": "The Effect of Shenmai Injection on the Expression of Hypoxia-inducible Factor 1-α in the Perihematomal Area in Rat with Intracerebral Hemorrhage",
        "abstract": "Objective To study The effect of Shenmai Injection on the expression of hypoxia-inducible factor 1-α(hypoxia inducible factor 1-α,HIF1-α) in the perihematomal area in rat with intracerebral hemorrhage and its significance.Methods Fifty rats were randomized into 4 groups:Normal group,sham operation group,model group and treatment group with Shenmai Injection.The rats in the model groups and treatment groups were prepared at 1 d,3 d,5 d and 7 d,respectively after operation.The models were established by injecting collagenase type Ⅶ stereotaxically.The pathologic signs of the nerve system were observed.The expression of hypoxia-inducible factor 1-α in the perihematomal area were analyzed by immunohistochem.Results Compared with model groups,the pathologic signs of the nerve system were alleviated,hematoma were absorbed well and the structure of neurons were relatively integrated(P<0.01).There was no expression of HIF1-α in the normal groups and sham operation groups.However,the expressions of HIF1-α in the of rats neurons in the perihematomal area increased at 1st day,got to a peak at 3rd day,decreased gradually at 5th day and kept higher at 7th day.There were obvious significant differences between treatment group with Shenmai Injection and model groups(P<0.01).Conclusion Shenmai Injection might have a protective effect on the rats after ICH,which might be activated by promoting the absorption of hematoma and inhibiting of the expression of HIF1-α.",
        "keywords": [
            "intracerebral hemorrhage",
            "hypoxia inducible factor 1-α",
            "Shenmai Injection"
        ],
        "authors": [
            {
                "name": "Huang Renfa",
                "org": ",et al The First Affiliated Hospital,Guangxi College of Traditional Chinese Medicine%%#Nanning %%#"
            },
            {
                "name": "He Zeyun",
                "org": ",et al The First Affiliated Hospital,Guangxi College of Traditional Chinese Medicine%%#Nanning %%#"
            },
            {
                "name": "Shi Wei",
                "org": ",et al The First Affiliated Hospital,Guangxi College of Traditional Chinese Medicine%%#Nanning %%#"
            }
        ],
        "venue": "Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease",
        "year": 2007
    },
    "BJ7tLUer": {
        "id": "BJ7tLUer",
        "title": "Analysis of risk factors for traumatic intraparenchymal contusion and hematoma progression in the acute post-injury period",
        "abstract": "Objective To analyze the risk factors for traumatic intraparenchymal contusion and hematoma(IPH) progression in the acute post-injury period.Methods Data of 159 head trauma patients with IPH were retrospectively analyzed about the mechanism and location of injury,coagulation,GCS score and presence of merging other hematoma.Results Of 159 cases,hematoma shranked in 10 cases,remained unchanged in 95 cases and enlarged in 59 cases between the first and repeat CT scan.IPH progression was independently associated with the initial size of the hemotoma,the presence of subarachnoid hemorrhage or subdural hematoma(P<0.05).The size of initial IPH was proportionately correlated with the amount of subsequent growth(P<0.05).Conclusion The progress in the majority of IPH appears in the acute post-injury period.IPH associated with subarachnoid hemorrhage or subdural hematoma and bigger initial hematoma are the risk factors for IPH,which should be monitored with dynamic head CT scan.",
        "keywords": [
            "Intraparenchymal contusion and hematoma"
        ],
        "authors": [
            {
                "name": "SU Xing",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "NI Lanchun",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2011
    },
    "GEJR2TIE": {
        "id": "GEJR2TIE",
        "title": "A General Picture of Climate Change and the Evolution of Regional Culture of China in the Prehistoric Period",
        "abstract": "In this article,environmental archaeology,climatic change and environment evolution etc.in Holocene epoch at home and abroad are presented through an investigation on the research results in the latest two decades on archaeology.Through analysis,it is found in the Holocene epoch there are at least 12 cultural-evolution-type regions in China,in which climate change plays an important role.It is hoped a comprehensive review of the research progress may expand the research ideology for the relative subjects.",
        "keywords": [
            "a general picture",
            "evolution of regional culture",
            "climatic change",
            "prehistoric period",
            "china"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Deparment of Geography,Jiangsu Institute of Education,Nanjing,Jiangsu,,China"
            }
        ],
        "venue": "Journal of Jiangsu Institute of Education(Natural Science)",
        "year": 2009
    },
    "SukS4pPt": {
        "id": "SukS4pPt",
        "title": "Synthesis and biological evaluation of novel aliphatic acid-conjugated antimicrobial peptides as potential agents with anti-tumor, multidrug resistance-reversing activity and enhanced stability.",
        "abstract": "Compared with traditional anti-tumor drugs, antimicrobial peptides as novel anti-tumor agents have prominent advantages of higher specificity and circumvention of multi-drug resistance. BP100 is a multifunctional membrane-active peptide with high antimicrobial activity. Taking BP100 as a lead peptide, we designed and synthesized a series of aliphatic chain-conjugated peptides through solid-phase synthesis. Biological evaluation revealed that these peptides exhibited better anti-cancer activity than BP100. Further investigations revealed that these peptides could disrupt the cell membrane and trigger the cytochrome C release into cytoplasm, which ultimately resulted in apoptosis. Meanwhile, these peptides also exhibited effective anti-tumor activity against multidrug resistant cells and had multidrug resistance-reversing effect. Additionally, conjugation of aliphatic acid to those peptides could enhance their stability in plasma. In conclusion, aliphatic acid-modified peptides might be promising anti-tumor agents for cancer therapy.",
        "keywords": [
            "Aliphatic chain",
            "Anti-cancer",
            "Antimicrobial peptides",
            "Drug resistance-reversing effects",
            "Membrane disruption"
        ],
        "authors": [
            {
                "name": "Bo Zhang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Haitao Gu",
                "org": "Sinopep Jiangsu Inc., Lianyungang, 222000, People's Republic of China."
            },
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Huilan Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Guanglan Ma",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Xiaolian Chen",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Hai Qian",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Haiyan Lin",
                "org": "Department of Biochemistry and Molecular Biology, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, People's Republic of China. qlhy24@163.com."
            },
            {
                "name": "Wenlong Huang",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China. ydhuangwenlong@126.com."
            },
            {
                "name": "Liang Ge",
                "org": "Department of Pharmaceutical, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China. geliang1981@hotmail.com."
            }
        ],
        "venue": "Amino acids",
        "year": 2017
    },
    "35xHM5mV": {
        "id": "35xHM5mV",
        "title": "Surface Rupture Investigation of the Wenchuan Ms 8.0 Earthquake of May 12th,2008,West Sichuan,and Analysis of Its Occurrence Setting",
        "abstract": "Field investigation and measurements of the surface ruptures were conducted immediately after the occurrence of the Wenchuan Ms 8.0 Earthquake of May 12th,2008.The data of surface deformation and co-seismic displacements obtained during this excursion confirm that the Wenchuan earthquake belongs to the reverse faulting type,the surface ruptures occurred mostly along the Yingxiu-Beichuan fault zone and partly along the Guanxian-Anxian fault zone.The surface rupture zone produced by the Wenchuan earthquake exhibits characteristic segmentation behavior,its southern segment between the Yingxiu Township and Beichuan county is reverse faulting dominated,while the segment north of Beichuan county shows important dextral strike-slip component.",
        "keywords": [
            "Wenchuan earthquake",
            "earthquake occurrence setting",
            "reverse faulting",
            "surface rupture"
        ],
        "authors": [
            {
                "name": "DONG Shuwen",
                "org": ")1) Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "ZHANG Yueqiao",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "LONG Changxing",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "WU Zhenhan",
                "org": ")1) Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "AN Meijian",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "ZHANG Yongshuang",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "YANG Nong",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "CHEN Zhengle",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "LEI Weizhi",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "SHI Jusong",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2008
    },
    "oNbnCdzR": {
        "id": "oNbnCdzR",
        "title": "First-principles investigation of a β-MnO2 and graphene composite as a promising cathode material for rechargeable Li-ion batteries",
        "abstract": "In this investigation, we studied the effect of the synergistic mechanism on the stability and the electronic and Li diffusion performance of a β-MnO2 and graphene composite. The C–O covalent bonds formed in the stable interface not only improved the hybrid structure stability (a stable C–O bond forms between the β-MnO2 (110) plane and graphene) but also led to enhanced conductivity. The calculated results implied that a possible diffusion pathway with the lowest energy barrier was found along the hybrid structure interface.",
        "keywords": "",
        "authors": [
            {
                "name": "Renhui Zhang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University,Tongren,P. R. China"
            },
            {
                "name": "Juan Zhao",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University,Tongren,P. R. China"
            },
            {
                "name": "Lei Guo",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University,Tongren,P. R. China"
            },
            {
                "name": "Hangdao Qin",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University,Tongren,P. R. China"
            },
            {
                "name": "Wei Shi",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University,Tongren,P. R. China"
            },
            {
                "name": "Zhibin Lu",
                "org": "Lanzhou Institute of Chemical Physics,Lanzhou 730000,P. R. China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2017
    },
    "Uj2Joyfu": {
        "id": "Uj2Joyfu",
        "title": "Time-averaged serum potassium levels and its fluctuation associate with 5-year survival of peritoneal dialysis patients: two-center based study.",
        "abstract": "The time-averaged serum potassium was more comprehensive to reflect the all-time changes of serum potassium levels during peritoneal dialysis (PD). However, the association of fluctuation of time-averaged serum potassium level with long-time survival of PD patients remains unknown. In this retrospective study, we included 357 incident PD patients in 2 centers from January 1, 2007 to October 31, 2012 with follow-up through October 31, 2014. Our data demonstrated that it was the lower time-averaged serum potassium level rather than baseline of serum potassium level that was associated with high risk of death. Patients with higher standard deviation (SD) had significantly poorer all-cause (p = 0.016) and cardiovascular mortality (p = 0.041). Among the patients with time-averaged serum potassium levels below 4.0 mEq/L, a lower mean value was more important than its SD to predict death risk. In contrast, the patients with time-averaged serum potassium levels above 4.0 mEq/L, those with serum potassium SD < 0.54 mEq/L, exhibited a higher 3-year and 5-year survival rate for both all-cause and cardiovascular mortality compared to the control groups. Our data clearly suggested both time-averaged serum potassium and its fluctuation contributed disproportionately to the high death risk in PD patients.",
        "keywords": [],
        "authors": [
            {
                "name": "Shen-Heng Li",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Jian-Teng Xie",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Hai-Bo Long",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Jun Zhang",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Wei-Dong Zhou",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Hong-Xin Niu",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Xun Tang",
                "org": "Division of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China."
            },
            {
                "name": "Zhong-Lin Feng",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Zhi-Ming Ye",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Yang-Yang Zuo",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Lei Fu",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Feng Wen",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Li-Ping Wang",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Wen-Jian Wang",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            },
            {
                "name": "Wei Shi",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical science, Guangzhou, 510080, China."
            }
        ],
        "venue": "Scientific reports",
        "year": 2015
    },
    "wzsFzqat": {
        "id": "wzsFzqat",
        "title": "The Multi-channel Audio Sampling System Based on CPLD",
        "abstract": "This paper introduces and implements a kind of multi-channel high-speed audio data sampling system that can adapt to various application environments.",
        "keywords": [
            "audio sampling",
            "I2S",
            "CPLD"
        ],
        "authors": [
            {
                "name": "ZHANG Hong",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "QI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "3mracMOF": {
        "id": "3mracMOF",
        "title": "The complete mitochondrial genome of Liachirus melanospilos (Pleuronectiformes: Soleidae).",
        "abstract": "Abstract Liachirus melanospilos (Pleuronectiformes: Soleidae) is characterized by both eyes on the right side of the body and pale brown color with black dots, small irregular, brown spots and large vague ocelli. In this study, the complete mitogenome sequence of this carpet sole has been determined. The total length is 17,001 bp, including 13 protein-coding genes, 22 tRNA genes and 2 rRNA genes (12S and 16S), as well as one control region and one L-strand replication origin (OL). Gene contents, locations and arrangements are identical to those of typical bony fishes. The nucleotide composition of the genome is 30.9%, 27.8%, 15.9% and 25.5% for A, C, G and T, respectively, with a slight bias of A + T content (56.4%). The determination of L. melanospilos complete mitogenome sequence could contribute to a better understanding of the systematic evolution of Soleidae and Pleuronectiformes.",
        "keywords": [
            "mtdna"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-Resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China and."
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Shu-Ying Wang",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2014
    },
    "chKA5m0N": {
        "id": "chKA5m0N",
        "title": "Forming compliant contact pads for semiconductor packages",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qing zhou",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2011
    },
    "sukdC49B": {
        "id": "sukdC49B",
        "title": "Independent Director Death and CEO Acquisitiveness: Build an Empire or Pursue a Quiet Life?",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Kelley School of Business‐Indianapolis, Indiana University Indiana U.S.A."
            },
            {
                "name": "Robert E. Hoskisson",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas U.S.A."
            },
            {
                "name": "Yan Anthea Zhang",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas U.S.A."
            }
        ],
        "venue": "Strategic Management Journal",
        "year": 2014
    },
    "VmWoKFAl": {
        "id": "VmWoKFAl",
        "title": "The Evolution of Social Practice for College Students and Its Reflections",
        "abstract": "In order to further improve college students' social practice work,provide reference and guidance for cultivating qualified builders and reliable successors of socialist undertakings with Chinese characteristics,the article tries to show every developmental stage of college students' social practice to explore their process and typical features from the social backeground and the history of higher education.",
        "keywords": [
            "Reflections and development",
            "Reference Guide",
            "College Students' social practice"
        ],
        "authors": [
            {
                "name": "CHENG Yong-sheng",
                "org": "Fuyang Teachers College,Fuyang ,Anhui"
            },
            {
                "name": "TAN Zhu-mao",
                "org": "Fuyang Teachers College,Fuyang ,Anhui"
            },
            {
                "name": "SHI Wei",
                "org": "Fuyang Teachers College,Fuyang ,Anhui"
            }
        ],
        "venue": "Journal of Fuyang Teachers College(Social Science Edition)",
        "year": 2013
    },
    "Xr4BnrRu": {
        "id": "Xr4BnrRu",
        "title": "The Optimized Thermoelectric Performance of Poly(3-hexylthiophene) through Molecular Weight Engineering.",
        "abstract": "Poly(3-hexylthiophene) (P3HT) films with various molecular weights (MWs) were successfully prepared, and both their molecular structures and thermoelectric (TE) properties were investigated. It was found that the molecular weight of P3HT had an important effect on the carrier-transport properties by affecting the molecular structure and, as a result, also had an effect on the TE performance. The electrical conductivity of the P3HT films first increased upon increasing the molecular weight and then decreased at high molecular weights, whereas the Seebeck coefficient remained at the same level. As a result, the P3HT-M-50k (MW approximate to 50 000 g mol(-1)) film reached an electrical conductivity of (103.8 +/- 1.2) S cm, which is more than 20 times higher than the electrical conductivity of P3HT-M-10k (MW approximate to 10 000 g mol(-1)) and almost 30 % higher than the electrical conductivity of P3HT-M-100k (MW approximate to 100 000 g mol(-1)). Consequently, the maximum TE power factor of P3HT-M-50k at room temperature was as high as (22.6 +/- 0.6) mu W mK(-2), which is much higher than that of either P3HT-M-10k or P3HT-M-100k. Microstructure analysis combined with C-AFM suggested that carrier transport between most of the ordered and amorphous regions was unconnected in films with low molecular weights, and this resulted in a high migration barrier and poor carrier mobility. Upon increasing the molecular weight, the long molecular chain provided enough connectivity for the charge to move through the ordered regions, which decreased the carrier barrier and increased carrier mobility. Therefore, both the conductivity and Seebeck coefficient were significantly improved. However, a too-high molecular weight could cause more folding of the polymer chain, which would deteriorate the electrical-transport properties. The experimental results not only reveal the intrinsic effect of molecular weight on the electric transporting properties of conducting polymers but also suggest that molecular-weight engineering is an effective way to design and screen high-performance polymer TE materials.",
        "keywords": [
            "electrical transport",
            "molecular weight",
            "organic thermoelectrics",
            "polymers",
            "thin films"
        ],
        "authors": [
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Bingxue Yu",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Kaiyang Zeng",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Yanling Chen",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "CHEMISTRY-AN ASIAN JOURNAL",
        "year": 2018
    },
    "BPUxEJ2e": {
        "id": "BPUxEJ2e",
        "title": "Failure Patterns and Ultimate Bearing Capacity Analysis of 220kV Tranmission Tower under Icing Conditons",
        "abstract": "In order to study the collapse and damage of tranmission towers as well as reinforcement and enhancement mesures for anti-icing designe of transmission towers under unbalanced tensions in southern China in 2008,the TTA and ANSYS softwares are used to analyze the force situation of 220 kV double-circuit drum tower under the conditions of non-uniform icing.The weak zones,destructive models and ultimate bearing capacity of drum tower are determined on the basis of mechanical analysis.",
        "keywords": [
            "non-uniform icing",
            "tranmission tower",
            "stress analysis",
            "damage pattern",
            "ultimate bearing capacity"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "LI Yanxia",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "LI Zhengda",
                "org": "Yannan Substation,Jinzhou Extra-high Voltage Bureau of Liaoning Province,Jinzhou ,China"
            }
        ],
        "venue": "Water Resources and Power",
        "year": 2011
    },
    "Eg9T9GJ6": {
        "id": "Eg9T9GJ6",
        "title": "The Effect of Shenmai Injecton on the Expression of Hypoxia-inducible Factor 1-α in the Sprapue-Dewley Rat with Intracerebral Hemorrhage",
        "abstract": "Objective:To study The effect of Shenmai Injecton on the expression of hypoxia-inducible factor 1-α(Hypoxia inducible factor 1-α,HIF1-α)in the perihematomal area in the Sprapue-Dewley Rat with intracerebral hemorrhage and its significance.Methods:The 50 rats were randomized into 4 groups:normal groups,false operation groups,modeling groups,and treating groups with Shenmai Injection,the rat both in the modeling groups and treating groups with Shenmai were made into four stages respectively in 1d,3d,5d,7d after operation,the rat models were made by injecting Collagenase type Ⅶ stereotaxically;we observed the change of he pathologic sign of the nerve system and the expression of hypoxia-inducible factor 1-α in the perihematomal area by immunohistochem,we also observed the effect of Shenmai Injecton on them.Results:Compared with modeling groups,the pathologic signs of the nerve system were alleviated,hematoma were absorbed well,the structure of neurons were relatively integrated(P<0.01);there is no expression of HIF1-αin the rats neurans of normal groups and false operation groups.However,the expressions of HIF1-αin the rats neurans of the perihematomal area increased at 1th day,get to a peak at the 3th day,followly decreased gradually at the 5th day,kept higher at the 7th day,there are obvious significant difference betwen treating group with Shenmai Injection and modeling groups(P<0.01).Conclusions:Shenmai injection may give a protective effect on the rats after ICH,which may be achived by promotting the absorption of hematoma and inhibting of the expression of HIF1-α.",
        "keywords": [
            "Sprapue-Dewley rats",
            "Shenmai Injection",
            "ICH",
            "HIF1-α"
        ],
        "authors": [
            {
                "name": "HUANG Ren-fa",
                "org": "The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha ,Hunan,China"
            },
            {
                "name": "HE Ze-yun",
                "org": "The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha ,Hunan,China"
            },
            {
                "name": "SHI Wei",
                "org": "The First Affiliated Hospital of Guangxi College of Traditional Chinese Nedicine,Nanning ,Guangxi,China"
            },
            {
                "name": "WU Jin-yu",
                "org": "The First Affiliated Hospital of Guangxi College of Traditional Chinese Nedicine,Nanning ,Guangxi,China"
            }
        ],
        "venue": "Liaoning Journal of Traditional Chinese Medicine",
        "year": 2008
    },
    "g72LbysT": {
        "id": "g72LbysT",
        "title": "Synthesis and Characterization of Phenylethynyl-Pendent-Decorated Thermal-Crosslinkable Alternating Polymer with Fluorene-Triphenylamine as Backbone",
        "abstract": "A kind of phenylethynyl-pendent-decorated conjugated polymer,consisting of alternating fluorene and triphenylamine gorups,(poly(9,)9-dioctyl)-2,7-fluorene-co-N-4-phenylethenyl-4,4'-tripheny-(lamine)(PFT-PE),was successfully synthesized via Suzuki coupling reaction.The chemical structure of PFT-PE was verified by NMR and FT-IR analyses.The polymer is highly soluble in common organic solvents,and exhibits good film-forming ability and thermal stability.The optical bandgap of this polymer is 2.82 eV,as deduced by its absorption onset.The PL spectrum of PFT-PE′s film showed substantial red-shift and broadening as relative to that of its THF solution,indicating the presence of intermolecular(aggregation) in solid state.The highest occupied molecular orbital(HOMO) level of PFT-PE is about(-5.39 eV,) as calculated by the oxidation onset of its CV curve.The highly reversible oxidation process indicates the good electrochemical stability PFT-PE possesses.PFT-PE can be thermally cured without the addition of any initiator due to the substitution of phenylethynyl pendant.",
        "keywords": [
            "triphenylamine",
            "fluorene",
            "crosslink",
            "hole-transport"
        ],
        "authors": [
            {
                "name": "YANG Sheng-xiong",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "PU Da-long",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "ZHOU Sen",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "LI Tian-yong",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "QIN Hong-mei",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Polymers",
        "year": 2010
    },
    "6ccK1seS": {
        "id": "6ccK1seS",
        "title": "Ternary Ni-Co-F Nanocrystal-Based Supercapacitors.",
        "abstract": "Ternary nickel cobalt fluoride (Ni-Co-F) nanocrystals are constructed solvothermally for use as the positive electrode materials in supercapacitors. The optimal Ni-Co-F (Ni/Co=2:1) shows slight chemical shifts in X-ray diffraction (XRD) data and X-ray photoelectron spectra (XPS) compared with bare Ni-F and Co-F. The Ni-Co-F (Ni/Co=2:1) exhibits typical square nanocrystal morphology together with a mesoporous surface structure, as observed through TEM observations and nitrogen sorption measurements. Owing to the stronger synergistic effect of Ni and Co redox species originated from the richer Ni and Co surface electroactive sites, Ni-Co-F (Ni/Co=2:1) shows superior performances of specific capacitance, rate capability, and charge-transfer kinetics (564 F g at 1 Ag , 418 F g at 16 Ag , 449 Ω) compared with all the other Ni-Co-F candidates. Moreover, the activated carbon (AC)//Ni-Co-F (Ni/Co=2:1) asymmetric capacitor designed based on charge balance delivers superior energy and power densities (18.4 Wh kg , 6.64 kW kg ) together with longer cycle life (77 % retention after 10 000 cycles at 4 A g ).",
        "keywords": [
            "electrochemistry",
            "nanoparticles",
            "nickel cobalt fluorides",
            "solvothermal reactions",
            "supercapacitors"
        ],
        "authors": [
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P. R. China."
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P. R. China."
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P. R. China."
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P. R. China."
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P. R. China."
            }
        ],
        "venue": "Chemistry (Weinheim an der Bergstrasse, Germany)",
        "year": 2017
    },
    "qsOV6Qqv": {
        "id": "qsOV6Qqv",
        "title": "Microdissection of petroclival region in temporal base transpetrosai transtentorial approach",
        "abstract": "Objective: To explore the important anatomical structures of temporal bone and petroclival region in temporal base transpetrosal transtentorial approach. Methods: Ten dried skulls for a total of 20 sides were used to explore the morphometric relationships. The anatomical relationships and distance among the correlated structures in temporal base transpetrosal transtentorial approach were studied and measured. Results: The distance between the anterior border of the external auditory foramen and the root of zygoma, superior border and the bone tuberositas above external auditory foramen, posterior border and the anterior angle of parietomastoid sutures, were 13.80±1.33mm, 6.18±1.20mm,and 26.18±3.90mm; the distance between the foramen lacerum and the petrous apex impression by trigeminal nerve was 6.62±1.66mm; the distance between the hiatus canalis facialis and petrous ridge was 11.79±1.00mm. The location of the internal auditory canal was on the angular bisector of the angle form by the arcuate eminence and the nervus petrosus superficialis major. The distance from the common crus to posterior border of the internal auditory foramen was 9.30±0.58mm; from cochlea to petrous ridge was 8.00±1.07mm; from the posterior semicircular canal to the petrous ridge was 4.30±0.60mm; and from the internal carotid canal to the petrous ridge was 10.47±1.34mm. Conclusions: The eminence part of the mastoid superior ridge can indicate the STP. The dura of the front petrous bone should be dissect within the field formed by the hiatus canalis facialis. The petrous bone can be divided into three parts: the medial、intermediate and lateral part, and the safety resecting field is different in each part.",
        "keywords": [
            "Microdissection",
            "Petroclival region",
            "Temporal base transpetrosal transtentorial approach"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong "
            },
            {
                "name": "XU Qiwu",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong "
            },
            {
                "name": "CUI Daming",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong "
            }
        ],
        "venue": "Nantong University Journal of Medical Sciences",
        "year": 2007
    },
    "gvhPNM4V": {
        "id": "gvhPNM4V",
        "title": "Study of fundamental ferroresonance on neutral-grounded systems by using analytical method-solution to the power frequency excitation characteristic of nonlinear inductors",
        "abstract": "It is vital to choose the right excitation characteristic of the nonlinear inductor when analyzing ferroresonance. The traditional excitation characteristic (TEC) has been commonly employed. Due to the voltage or current harmonics in the TEC, the analysis does not necessarily lead to a correct conclusion. To filter out the harmonics and hence obtain the power frequency excitation characteristic (PEC), two methods are presented. One is fulfilled by EMTP simulation, which results in discrete points of the PEC. The other is based on series technique, and an analytical expression is achieved to approximate the PEC. The two methods match well in the saturated region (ferroresonant region) of the PEC.",
        "keywords": [
            "EMTP",
            "Ferroresonance",
            "Inductance",
            "Nonlinear circuits",
            "Potential transformer"
        ],
        "authors": [
            {
                "name": "Yunge Li",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2003
    },
    "x46NSNGS": {
        "id": "x46NSNGS",
        "title": "AFMC:A Novel Automated Flow for Asynchronous Circuit Design",
        "abstract": "As the CMOS technology enters the deep submicron design era,the richness of computational resources brings a lot of problems,such as complex clock distribution,great clock skew and high power dissipation.Asynchronous circuit style is an efficient approach to solve the problems,and it is becoming significantly attractive to designers.The asynchronous circuit design flow based on macrocells can convert a synchronous circuit to an asynchronous counterpart efficiently using current EDA tools and industrial libraries for the synchronous circuit design.In this paper,a fully-automated asynchronous circuit design flow based on macrocells is presented,and it is also compared with the fully-automated desynchronization flow.The fully-automated desynchronization flow generates asynchronous circuits from the gate-level netlist,while our flow works from the register transfer level specification.Then,the proposed flow is used to implement a simple DLX RISC microprocessor in UMC 0.18 μm industrial library.The experiment shows that the fully-automated flow can accelerate the asynchronous circuit design and the logic delay of datapath in the macrocell based asynchronous circuit can be significantly optimized.Furthermore,the newly proposed flow can achieve an average of 6% speedups,when compared with the desynchronized DLX microprocessor for a subset of the Mibench benchmark suite.",
        "keywords": [
            "design flow",
            "asynchronous circuit",
            "desynchronization",
            "design automation",
            "macrocell"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Ren Hongguang",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Wang Zhiying",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Lu Hongyi",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Wang Yourui",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Su Bo",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            }
        ],
        "venue": "Journal of Computer Research and Development",
        "year": 2011
    },
    "lNgtQztw": {
        "id": "lNgtQztw",
        "title": "A PUSHOVER ANALYSIS ALGORITHM BASED ON MULTIPLE POINT CONSTRAINTS",
        "abstract": "This paper proposes a new numerical method for pushover analysis.By using multiple point constraints,the lateral force distribution is maintained and displacement-controlled pushover analysis is achieved.The method is derived from the principle of virtual work and the rigidity of multiple point constraint.It is applicable to both elastic and inelastic structures.The proposed pushover analysis method can be implemented with user-defined subroutine interfaces of finite element software MSC.MARC.The outstanding performance of the method is then demonstrated using monotonic and cyclic pushover analysis of reinforced concrete structures.The evolution of deterioration from onset to eventual member and structural failure can be tracked,suggesting that the proposed method is a powerful tool offering complete pictures and considerable insight into pushover performance and collapse mechanism of structures.",
        "keywords": [
            "collapse analysis",
            "principle of virtual work",
            "multiple point constraint",
            "displacement control",
            "pushover analysis"
        ],
        "authors": [
            {
                "name": "HUANG Yu-li",
                "org": "Department of Civil and Environmental Engineering,University of California,Berkeley,CA 94720,US"
            },
            {
                "name": "LU Xin-zheng",
                "org": "Department of Civil Engineering,Key Laboratory of Structural Engineering and Vibration of China Education Ministry, Tsinghua University,Beijing ,China"
            },
            {
                "name": "YE Lie-ping",
                "org": "Department of Civil Engineering,Key Laboratory of Structural Engineering and Vibration of China Education Ministry, Tsinghua University,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Civil Engineering,Key Laboratory of Structural Engineering and Vibration of China Education Ministry, Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Engineering Mechanics",
        "year": 2011
    },
    "B4698EV5": {
        "id": "B4698EV5",
        "title": "Atomistic simulation of the mechanical properties of β-SiC based on the first-principles",
        "abstract": "Abstract   On the basis of the pseudopotential plane-wave method and the local-density-functional theory, this work studied the energetics and stress-strain relationship of  β -SiC, where uniform uniaxial compression and tension were considered along (001), (110) and (111) planes. The calculated results were in consistence with the experimental data. The present work should be conducive to understanding the mechanical property of  β -SiC.",
        "keywords": "",
        "authors": [
            {
                "name": "Renhui Zhang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren 554300, PR China"
            },
            {
                "name": "Senlin Leng",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren 554300, PR China"
            },
            {
                "name": "Yingchang Yang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren 554300, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren 554300, PR China"
            },
            {
                "name": "Zhibin Lu",
                "org": "Lanzhou Institute of Chemical Physics, Lanzhou 730000, PR China"
            }
        ],
        "venue": "Physica B-condensed Matter",
        "year": 2017
    },
    "wJvkn8Ka": {
        "id": "wJvkn8Ka",
        "title": "The Application of Zigbee Technology in Hydrological Information Monitoring System",
        "abstract": "In the light of the disadvantages of the current hydrological information monitoring system such as the complicated structure,difficult maintenance,and poor anti-interference performance,etc.,this paper applies Zigbee technology and wireless sensor technology into the system,and designs its network structure,node hardware circuit,network protocol and software,and realizes the real time monitoring of hydrological information,which provides a new hydrological information monitoring technology with lower cost,lower energy consumption and higher reliability for water conservancy departments.",
        "keywords": [
            "wireless sensor technology",
            "network structure",
            "hydrological information monitoring system",
            "node hardware circuit",
            "Zigbee technology"
        ],
        "authors": [
            {
                "name": "ZHAO Xiang-yu",
                "org": ""
            },
            {
                "name": "Shi Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2011
    },
    "dKTpjyPN": {
        "id": "dKTpjyPN",
        "title": "Function Design and Procedure Realization of Resident Memory",
        "abstract": "Resident memory procedure solves the limitation of single user and single duty of PC DOS effectivly.Embarking from the concrete example,this article introduced its principle and implementation step.Thoroughly introduced all sorts of questions and its solution which possibly meet in the hot key conflict,the demonstration,the DOS transfer nesting and so on.Fully discussed compatible question between resident program each other as well as with other procedure.",
        "keywords": [
            "severance",
            "advancement",
            "resident memory procedure",
            "activation symbol"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Liaoning Technical University,Huludao ,China"
            },
            {
                "name": "LIU Jian-hui",
                "org": "Liaoning Technical University,Huludao ,China"
            }
        ],
        "venue": "Computer Technology and Development",
        "year": 2007
    },
    "7wfaszv5": {
        "id": "7wfaszv5",
        "title": "The Need of the Rural Education and the knowledge of Teacher",
        "abstract": "Many researchers think recently that teachers in rural areas are lack of teaching profession,teaching research and teaching confidence.In fact,rural teachers have their own developing tasks and goals from the demands of rural students,the community and the science.Thus,rural teachers should establish unique professional knowledge,practical knowledge and behavior patterns.",
        "keywords": [
            "knowledge of teacher",
            "rural education",
            "practical knowledge"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Education,Fuyang Teachers College,Fuyang,Anhui ,China"
            }
        ],
        "venue": "University Education Science",
        "year": 2008
    },
    "f7ojnTK9": {
        "id": "f7ojnTK9",
        "title": "Calculation and analysis of a switchgear fault caused by lightning strike on 220 kV transmission lines",
        "abstract": "Flashovers or even explosions of switchgears fixed on substations and power plant at the voltage rank of 220 kV or below, which were caused by lightning intrusive waves, have taken place frequently in east China in recent years. In July 2007, this kind of event occurred because of lightning strike on the 220 kV transmission line, which generated the circuit breaker flashover and current transformer dielectric breakdown. This paper simulates the accident considering the running condition, and obtains the lightning over-voltages by the software EMTP. According to the over-voltage values, the reasons of the accident are analysed, and some protection methods from over-voltage due to lightning intrusive wave are presented by installing MOAs at both ends of the 220 kV transmission lines.",
        "keywords": [
            "Breakdown",
            "Circuit breaker",
            "Flashover",
            "Lightning intrusive wave",
            "Over-voltage"
        ],
        "authors": [
            {
                "name": "RongMing Tao",
                "org": "East China Electric Power Dispatch Center(East China Electric Power Dispatch Center,East China Electric Power Dispatching Center),Shanghai,China"
            },
            {
                "name": "LiangJin Chen",
                "org": "Zhejiang Electric Power Test and Research Institute(Zhejiang Electric Power Test and Research Institute),Hangzhou,China"
            },
            {
                "name": "Yuan Gao",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Gaoya Dianqi/High Voltage Apparatus",
        "year": 2008
    },
    "I8bYoU99": {
        "id": "I8bYoU99",
        "title": "DOCUMENT ANALYSIS ON FREQUENT OCCURRENCE OF THE EXCEPTIONAL PALEOFLOOD RECORDED BY YUXI STRATUM DURING CA. 6567～6489ABP IN THE UPPER REACHES OF THE YANGTZE RIVER",
        "abstract": "To improve the credibility of prehistory flood research,combining the field survey of sedimentary characteristics of modern flood as well as the correlation analysis between the archaeological sites and unordinary flood stage in history in the study area etc.,using the textual researches of the flood document in the history,this paper analyzed comprehensively the more than 1.5 m silt-sand layers which were deposited about during 6 567~6 489 aBP in Yuxi profile in the upper reaches of the Yangtze River,and discussed the authenticity,reliability,magnitude,characteristics and possible driving or influence factors of the paleoflood sedimentary phenomenon.The paleoflood layers formed about during 6 567~6 489 aBP in Yuxi profile reflected that there were more than 5 exceptional floods at least,which occurred about during the 78 a in the upper reaches of the Yangtze River in the mid Holocene,and it was possible that the more than 1.5 m flood deposits were remained.The characteristics which the return period(years) reflected by the stratum records in the mid Holocene and the exceptional floods recorded by the historical documents in study areas was very close or basically coincident with the change periods of ENSO.It indicated that,the frequency phenomena of exceptional floods might be linked to the change periods of ENSO in the upper reaches of the Yangtze River since the mid Holocene.",
        "keywords": [
            "document analysis",
            "frequent occurrence",
            "exceptional paleoflood",
            "Yuxi stratum",
            "the upper reaches of the Yangtze River"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Geography,Jiangsu Institute of Education,Nanjing ,China;Nanjing Institute of Geography & Limnology,Chinese Academy of Sciences,Nanjing ,China"
            },
            {
                "name": "ZHU Cheng",
                "org": "Institute of Geography & Oceanology Sciences, Nanjing University,Nanjing ,China"
            },
            {
                "name": "JIAO Feng",
                "org": "Department of Environmental Science & Engineering,SuZhou College of Science & Technology,Suzhou ,China"
            },
            {
                "name": "LI Shi-jie",
                "org": "Nanjing Institute of Geography & Limnology,Chinese Academy of Sciences,Nanjing ,China"
            }
        ],
        "venue": "Resources and Environment in the Yangtze Basin",
        "year": 2011
    },
    "eeIhrZMg": {
        "id": "eeIhrZMg",
        "title": "Nonlinear Characteristics of Runoff Processes of the Manas River in Xinjiang",
        "abstract": "Based on the monthly stream discharge data of Kenswat Station and the climate data of ten meteorological stations from 1954 to 2007 in the Manas River Basin,the paper studied the nonlinear characteristics of the Manas River runoff and affecting factors by using methods of wavelet transform,chaotic theory and the periodic trend superposition model.The results show that: 1) The primary periods of the annual runoff are respectively 15,18 and 22 years,but are most significant at just 18 years;2) the annual runoff change of the Manas River presents a complex nonlinearity,and the correlative dimension is 3.3178 which is non-integral,indicating that the variation process of the annual runoff has fractal and chaotic characteristic;3) based on the periodic trend superposition model,the annual runoff will keep an increasing trend in the coming seven years after 2007;4) the NAO has the best positive relationships with the runoff in winter,while in summer the relationships are negative and in annual the worst;and 5) the NAO has strong impacted on the climate variations which are caused by the atmospheric circulation in the Manas River Basin,then the runoff of the Manas River is affected.",
        "keywords": [
            "nonlinear characteristics",
            "Manas River Basin",
            "hydrology and water resources",
            "wavelet analysis"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography,Urumqi ,China"
            },
            {
                "name": "ZHANG Qing-qing",
                "org": "Xinjiang Institute of Ecology and Geography,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Natural Resources",
        "year": 2011
    },
    "RKrvVKTA": {
        "id": "RKrvVKTA",
        "title": "Exploration of novel pyrrolo[2,1-f][1,2,4]triazine derivatives with improved anticancer efficacy as dual inhibitors of c-Met/VEGFR-2.",
        "abstract": "c-Met and VEGFR-2 have attracted interest as novel targets for treatment of various cancers. Aiming to develop potent dual c-Met and VEGFR-2 inhibitors, a series of pyrrolo[1,2-f][1,2,4]triazine derivatives were designed and synthesized. The majority of target compounds exhibited potent antiproliferative effect against c-Met addictive cancer cell lines with IC values ranged from 1.2 to 24.6 nM, especially 27a. In-depth studies demonstrated 27a has great selectivity to c-Met and VEGFR-2, and potent inhibitory activity against them (IC of 2.3 ± 0.1 nM and 5.0 ± 0.5 nM). Furthermore, it also showed the highest anticancer activity with IC of 0.71 ± 0.16 nM (better than the positive compound) against BaF-TPR-Met and 37.4 ± 0.311 nM (comparable to the positive compound) against HUVEC-VEGFR2, consistent with that in c-Met sensitive tumor cell lines. Subsequently, physicochemical and pharmacokinetic characterization indicated 27a has favorable druggability and pharmacokinetic properties. Further docking studies suggested a common mode of interaction at the ATP-binding site of c-Met and VEGFR-2, also indicating that 27a was a potential candidate for cancer therapy deserving further study.",
        "keywords": [
            "Antiproliferative effect",
            "Cancer therapy",
            "Tumor angiogenesis",
            "c-Met/VEGFR-2"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China."
            },
            {
                "name": "Hao Qiang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China."
            },
            {
                "name": "Dandan Huang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China."
            },
            {
                "name": "Xinzhou Bi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China."
            },
            {
                "name": "Wenlong Huang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China. Electronic address: ydhuangwenlong@cpu.edu.cn."
            },
            {
                "name": "Hai Qian",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China. Electronic address: qianhai24@163.com."
            }
        ],
        "venue": "European journal of medicinal chemistry",
        "year": 2018
    },
    "dnSzzFgX": {
        "id": "dnSzzFgX",
        "title": "Analysis of the Photoelectric Delay Phenomenon of Photoconductive Switches in Nonlinear Mode",
        "abstract": "The experimental results that the semi-insulating GaAs photoconductive switches will enter into a nonlinear mode and photoelectric delay will happen under a high biased voltage are reported.The photoelectric delay in the nonlinear mode is analyzed and the main reason for this phenomenon is pointed out to be the trapping effect of deep level impurities in semiconductor materials.Photoelectric delay time caused by charge domain transmission is calculated,which shows a conformance with the experimental results.",
        "keywords": [
            "Deep level impurities",
            "Delay time",
            "Photoconductive switches"
        ],
        "authors": [
            {
                "name": "DAI Huiying",
                "org": "College of Science,Air Force Engineering University,Xi'an ,CHN"
            },
            {
                "name": "XIANG Shan",
                "org": "College of Science,Air Force Engineering University,Xi'an ,CHN"
            },
            {
                "name": "SHI Wei",
                "org": "Applied Physics Department,College of Science,Xi'an Polytechnic University,Xi'an ,CHN"
            }
        ],
        "venue": "Semiconductor Optoelectronics",
        "year": 2010
    },
    "QOMJXyxC": {
        "id": "QOMJXyxC",
        "title": "The Tectonic Stress Field in the Dabashan Orogen Resulting from Late Mesozoic Intra-Continental Orogeny",
        "abstract": "The Dabashan orogen, situated in the northern margin of the middle-upper Yangtze block, is marked by a  large-scale oroclinal structure belt evidently extruding southwestwards. By dividing its framework and observing defor- mation in the field work, and combining with geochronologic data obtained in recent years, the authors rebuilt a stage of  special stress field in the Dabashan orogen, which occurred during Late Mesozoic (late Middle Jurassic-early late of  Early Cretaceous) and caused by intense intra-continental orogeny. The episode of the stress field, bounded by the  Chengkou-Fangxian fault, is characterized by NE-SW trending tectonic compression in the Dabashan thrust belt, and  outward emanational compression in the Dabashan foreland belt which is featured by E-W trending compression in the west segment, NE-SW striking compression in the middle, and S-N trending compression in the east, respectively, that is,  it is approximately perpendicular to the oroclinal belt. Thus, controlled by the stage of stress field, and blocked from the  two blocks of its west and east sides, the arc-shaped Dabashan foreland finally formed, which resulted from multidirec- tional convergence occurring in eastern Asia in late Mesozoic.",
        "keywords": [
            "multidirectional convergence",
            "tectonic stress field",
            "Dabashan orogen",
            "Late Mesozoic",
            "intra-continental orogeny",
            "arc-shaped structure belt"
        ],
        "authors": [
            {
                "name": "DONG Shu-wen",
                "org": ") 1) Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "ZHANG Yue-qiao",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "HU Jian-min",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "ZHANG Zhong-yi",
                "org": " Beijing Institute of Geology for Mineral Resources,Beijing "
            },
            {
                "name": "LI Jian-hua",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "WU Hong-ling",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "TIAN Mi",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "CHEN Hong",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "WU Guo-li",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "LI Hai-long",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2010
    },
    "PyX1uMQx": {
        "id": "PyX1uMQx",
        "title": "Innovating Team Teaching Mode Based on Google Services",
        "abstract": "The new communication mode and relationship between teachers and students as well as the new teaching method gradually appear along with the development of the teaching reform of higher education in China.As Google provides many online services in a completely new mode,the paper introduces an investigating method of how to realize communication,resource share and team teaching with the Google service in realtime mode.",
        "keywords": [
            "Google service",
            "teaching",
            "team work"
        ],
        "authors": [
            {
                "name": "LI Ke-sheng",
                "org": "Center of Experiment Administration,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Center of Experiment Administration,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "LI Wei",
                "org": "Center of Experiment Administration,Zhongzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Journal of Zhongzhou University",
        "year": 2013
    },
    "9yR91kCh": {
        "id": "9yR91kCh",
        "title": "Jurassic sedimentary filling process of Zigui basin in the eastern section of Daba Mountain tectonic belt and Its structural evolution",
        "abstract": "The Zigui basin is a well-preserved Jurassic sedimentary basin that lies in the eastern section of Daba Mountain tectonic belt. Its sedimentary filling process and structural evolution can be divided into two distinct stages. The first stage is featured by extensional subsidence controlled by a northwest strike-slip fault in early Jurassic, while the second stage is characterized by contractional uplift in response to the rise of Huangling area in middle-late Jurassic. The conglomerate at the bottom of lower Juassic Xiangxi Formation marks the beginning of Zigui basin. The thick conglomerate layer distributing in the northern basin deposited in alluvial fan and braided river system. Some fossils preserved in limestone can be found as gravels, and this indicates deposition proximal to source area. The thinner conglomerate deposited in the meandering river is distributed around south and southeast of the basin. The restored paleo-currents and provenance analyses show that sediments were mainly from the Shennongjia area at the early stage. Mid Juassic Xietan Formation and Chenjiawan Formation are composed mainly of sandstone and mudstone, formed in lacustrine system at the early stage of middle Jurassic. The Shangshaximiao Formation and Xiashaximiao Formation are characterized by deposition in the steady or mature meandering river at the late stage of middle Jurassic, because the conglomerate contains no limestone and chert gravels but only mudstone gravel. The Suining Formation and Penglaizhen Formation were dominated by meandering fluvial facies, but the gravels preserved at the bottom of channel sandstone differ from those in middle Jurassic. The occurrence of limestone and chert gravels indicated the change of provenance area. In addition, the paleo-current was westward at the late stage of middle Jurassic and late Jurassic, which shows the Huangling area maybe provide much elastics. Sedimentary filling characteristics and the northwestern margin fault of the basin with sinistral strike-slip, as well as a number of south-dipping reverse faults on the north of basin-margin show that the Zigui basin was controlled by these faults. The uplifting of Huangling anticline strongly affected the evolution of Zigui basin in late Mesozoic, and resulted in the death of Zigui basin in late Jurassic. The sedimentary filling process and structural evolution of Zigui basin was in response to the \"Yanshan Movement\" in the eastern section of Daba Mountain tectonic belt.",
        "keywords": [
            "Huangling anticline",
            "Jurassic",
            "Provenance analysis",
            "Sedimentary",
            "Zigui basin"
        ],
        "authors": [
            {
                "name": "Hongjie Qü",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Jianmin Hu",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Jianjun Cui",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Guoli Wu",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Mi Tian",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Geosciences(Chinese Academy of Geosciences),Beijing,China"
            },
            {
                "name": "Shanlan Zhao",
                "org": "Shaanxi Bureau of Geological Exploration(Regional Institute of Shaanxi Bureau of Geological Exploration,Shaanxi Bureau of Geological Exploration,Bureau of Geology and Mineral Resources of Shaanxi Province,Shaanxi Bureau of Geological and Mineral Resources,The Regional Institute of Shaanxi Bureau of Geological Exploration),Xianyang,China"
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2009
    },
    "AgOZMnYk": {
        "id": "AgOZMnYk",
        "title": "Comparison of effects of different hemodialysis methods and membranes on clearance of serum cystatin C in uremic patients",
        "abstract": "Objective:To compare the changes of serum cystatin C concentration during hemodiafitration (HDF) and hemodialysis (HD)with different dialysis membranes. Methods:40 patients with uremia were divided into two groups, 20 cases in each group, who were treated with HDF or HD respectively.Patients in each group used cellulose triacetate membrane and polysulfon membrane respectively.The pre-dialysis and post-dialysis serum cystatin C concentrations were measured. Results:The levels of serum cystatin C in patients with HDF in post-dialysis were significantly lower than those in pre-dialysis[pre-hemodiafitration[(2.7±0.4) mg/L vs (3.8±0.7) mg/L,P<0.01].The levels of serum cystatin C in patients with HD in pre-dialysis significantly higher than those pre-dialysis[(4.7±0.6) mg/L vs (3.6±0.5) mg/L], P<0.01].The removal rate of serum cystatin C in patients with HDF or HD was no difference between cellulose triacetate and polysulfon menberane.Conclusion:Hemodiafiltration,but not hemodialysis can remove serum cystatin C effect ively. Cellulose triacetate and polysulfon membranes have no effect on removal rate of serum cystatin C.",
        "keywords": [
            "Uremia Cystatin C Hemodialysis Hemodiafitration Dialysis mambrane"
        ],
        "authors": [
            {
                "name": "Ye Zhiming",
                "org": ",et al.Department of Nephrology,The Guangdong Provincial People's Hospital, Guangzhou,,China"
            },
            {
                "name": "Shi Wei",
                "org": ",et al.Department of Nephrology,The Guangdong Provincial People's Hospital, Guangzhou,,China"
            },
            {
                "name": "Liang Xinling",
                "org": ",et al.Department of Nephrology,The Guangdong Provincial People's Hospital, Guangzhou,,China"
            }
        ],
        "venue": "New Chinese Medicine",
        "year": 2006
    },
    "2zZzDeEk": {
        "id": "2zZzDeEk",
        "title": "Method and arrangement for forming a microelectronic package",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "thomas j fitzgerald",
                "org": ""
            },
            {
                "name": "steve m mayer",
                "org": ""
            },
            {
                "name": "carl l deppisch",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "cmEGg7BU": {
        "id": "cmEGg7BU",
        "title": "Analysis of the System based on Quefrency Region",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "yonghui park",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "BLTT4pTt": {
        "id": "BLTT4pTt",
        "title": "Research on DC Motor Indirect Velocimetry Based on the Second Generation Wavelet",
        "abstract": "A DC motor indirect velocimetry new method was presented.Armature current acquisition was denoised,filtered and reconstructed to extract the high frequency commutation current by second generation wavelet transform from lifting scheme.Commutating current was analyzed by second generation wavelet packet decomposition.DC motor no-load starting speed curve was indirectly gotten by using wavelet packet good time-frequency localization characteristics.The experimental results show that the proposed method is valid.",
        "keywords": [
            "indirect velocimetry",
            "lifting scheme",
            "commutation current",
            "DC motor",
            "second generation wavelet transform"
        ],
        "authors": [
            {
                "name": "HUANG Chuan-jin",
                "org": "Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "LEI Gang",
                "org": "Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "CHEN Tie-jun",
                "org": "Zhengzhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Zhongzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Small & Special Electrical Machines",
        "year": 2013
    },
    "Wq98qiWn": {
        "id": "Wq98qiWn",
        "title": "A comparison of ITS sequence data and morphology for Calligonum pumilum and C. mongolicum (Polygonaceae) and its taxonomic implications",
        "abstract": "Several lines of evidence including morphology, chromosome numbers, karyotypes, and phenology were previously used to clarify the taxonomic relationship between  Calligonum mongolicum  and  C. pumilum  (Polygonaceae). We employed sequences of the commonly used bar-coding locus, the nuclear ribosomal ITS region, to differentiate  Calligonum mongolicum  and  C. pumilum , based on a sampling scheme of seven populations in three desert regions in China. Phylogenetic analyses did not support the monophyly of each of the two species; instead, populations of the two taxa are intermixed in the analysis. This pattern of intermixing is consistent with the result of the neighbor-net analysis. The ITS region can distinguish other species beyond the  C. mongolicum  complex defined by morphology both within a section and among sections in  Calligonum . The intermixed non-monophyletic pattern of the widespread  C. mongolicum  and the narrowly distributed  C. pumilum  supports the merge of  C. pumilum  with  C. mongolicum , consistent with morphological, cytological and karyotype analyses.   We herein formally treat  C. pumilum  as the synonym of  C. mongolicum .",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Jun Wen",
                "org": "Department of Botany, Smithsonian Institution, PO Box 37012, Washington, DC 20013-7012, USA"
            },
            {
                "name": "Borong Pan",
                "org": "Institute of Ecology and Geography in Xinjiang, Chinese Academy of Sciences, CN-830011 Urumqi, PR China#R##N#Turpan Eremophytes Botanic Garden, Chinese Academy of Sciences, CN-838008 Turpan, PR China"
            }
        ],
        "venue": "Phytotaxa",
        "year": 2016
    },
    "BFVSN73L": {
        "id": "BFVSN73L",
        "title": "Subtemporal Transtentorial Keyhole Approach to Petroclival Region and Post-cavernous Sinus",
        "abstract": "Objective To study the micro-anatomic structure of petroclival region and post-cavernous sinus via subtemporal transtentorial keyhole approach,and provide anatomic basis in clinical use to deal with the disease in this area.Meanwhile,the limitations of this approach can be chiscussed.Methods Ten formalin-fixed adult cadaver heads of twenty sides were used for simulating subtemporal transtentorial keyhole approach to observe the structure of petroclival region and post-cavernous sinus.Results Through this approach the mid-skull base above tentorial and the cavernous sinus could be easily exposed.The oculomotor nerve,trochlear nerve,trigeminal nerves,cisterna ambiens,posterior communicating artery,cupular part of basilar artery,posterior cerebral artery,the ante-lateral mesencephalon and so on could be exposed after opening the tentorial.But the os petrosum face to posterior cranial fossa could not be seen because of the hinder of os petrosum.Conclusion The subtemporal transtentorial keyhole approach has the same exposure like the traditional subtemporal approach,it minimize the trauma and can be operated easily.But it has some limitations in dealing with large tumors in petroclival region when the base of the tumor locates on the petrous bone face to the posterior cranial fossa.",
        "keywords": [
            "subtemporal transtentorial approach",
            "petroclival region",
            "keyhole approach"
        ],
        "authors": [
            {
                "name": "LI Zheng-yi",
                "org": "Dept of Neurosugery,the Hospital Affiliated to Nantong University,Jiangsu Nantong ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Dept of Neurosugery,the Hospital Affiliated to Nantong University,Jiangsu Nantong ,China"
            },
            {
                "name": "NI Lan-chun",
                "org": "Dept of Neurosugery,the Hospital Affiliated to Nantong University,Jiangsu Nantong ,China"
            },
            {
                "name": "ZHU Song-hua",
                "org": "Dept of Neurosugery,the Hospital Affiliated to Nantong University,Jiangsu Nantong ,China"
            },
            {
                "name": "CHEN Jian",
                "org": "Dept of Neurosugery,the Hospital Affiliated to Nantong University,Jiangsu Nantong ,China"
            }
        ],
        "venue": "Suzhou University Journal of Medical Science",
        "year": 2010
    },
    "nSGaVbSM": {
        "id": "nSGaVbSM",
        "title": "Occurrence of thyroid hormone activities in drinking water from eastern China: contributions of phthalate esters.",
        "abstract": "Thyroid hormone is essential for the development of humans. However, some synthetic chemicals with thyroid disrupting potentials are detectable in drinking water. This study investigated the presence of thyroid active chemicals and their toxicity potential in drinking water from five cities in eastern China by use of an in vitro CV-1 cell-based reporter gene assay. Waters were examined from several phases of drinking water processing, including source water, finished water from waterworks, tap water, and boiled tap water. To identify the responsible compounds, concentrations and toxic equivalents of a list of phthalate esters were quantitatively determined. None of the extracts exhibited thyroid receptor (TR) agonist activity. Most of the water samples exhibited TR antagonistic activities. None of the boiled water displayed the TR antagonistic activity. Dibutyl phthalate accounted for 84.0-98.1% of the antagonist equivalents in water sources, while diisobutyl phthalate, di-n-octyl phthalate and di-2-ethylhexyl phthalate also contributed. Approximately 90% of phthalate esters and TR antagonistic activities were removable by waterworks treatment processes, including filtration, coagulation, aerobic biodegradation, chlorination, and ozonation. Boiling water effectively removed phthalate esters from tap water. Thus, this process was recommended to local residents to reduce certain potential thyroid related risks through drinking water.",
        "keywords": [],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xinxin Hu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Fengxian Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Guanjiu Hu",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Yingqun Hao",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Xiaowei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongling Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xinru Wang",
                "org": "Nanjing Medical University(Nanjing Medical University),Nanjing,China"
            },
            {
                "name": "John P Giesy",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2012
    },
    "HDAOVo8e": {
        "id": "HDAOVo8e",
        "title": "Detection of serum Alu element hypomethylation for the diagnosis and prognosis of glioma.",
        "abstract": "Global genomic hypomethylation is a hallmark of cancer in humans. In the present study, the feasibility of measuring hypomethylation of Alu elements (Alu) in serum and its clinical utility were investigated. Tumor tissues and matched serum specimens from 65 glioma patients and serum samples from 30 healthy controls were examined for Alu hypomethylation by bisulfite sequencing. The median serum Alu methylation level was 47.30 % in patients (interquartile range (IQR), 35.40-54.25 %) and 57.90 % in the controls (IQR, 55.25-61.45 %). The median Alu methylation level in tumor samples was 40.30 % (IQR, 36.80-54.20 %), which shows the correlation of Alu hypomethylation between tumor and serum samples (r = 0.882) in the study group. The methylation level was higher in the low-grade glioma group than in the high-grade group both in tumor and serum samples. A correlation between high methylation level and longer survival time was detected in tumor and serum samples. Receiver operating characteristic curve analysis showed that the area under the curve for diagnosis was 0.861 (95 % confidence interval, 0.789-0.933), suggesting that Alu hypomethylation in serum may be of diagnostic value. Our results indicate that the detection of Alu hypomethylation in serum may be clinically useful for the diagnosis and prognosis of glioma.",
        "keywords": [
            "Serum",
            " Alu",
            " Hypomethylation",
            " Glioma"
        ],
        "authors": [
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu Province, China 226001."
            },
            {
                "name": "Mingjie Gong",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Shendong Lu",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Futian Liu",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Liang Xia",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Dekang Nie",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Feihui Zou",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Jinlong Shi",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Shaoqing Ju",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Longxiang Zhao",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Hao Zuo",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Jing Qi",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery, Comprehensive Surgical Laboratory,Affiliated Hospital of Nantong University,Nantong,China"
            }
        ],
        "venue": "Journal of molecular neuroscience : MN",
        "year": 2013
    },
    "jwob612n": {
        "id": "jwob612n",
        "title": "Modeling and scaling of chielectric relaxation of nonlinear optical polymers in frequency domain",
        "abstract": "Chielectric relaxation theory was demonstrated, chielectric relaxation that selectively probes chromophore reorientation in the frequency domain was described by the Havriliak Negami (HN) function, chielectric spectra of several nonlinear optical (NLO) polymers were fitted well by the HN function. To describe the scaling of chromophore reorientation relaxation in frequency domain, two-shape parameters m and n describing the low- and high- frequency wings of the chielectric spectra need to be specified, besides the chielectric characteristic relaxation time τ and the chielectric strength Δχ(2). From the temperature dependences of m and n of NLO polymers, the relations between the chromophore relaxation and the α relaxation of the polymer host have been revealed.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Fang Chang-shui",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Pan Qi-wei",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xun Sun",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Gu Qing-tian",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Dong Xü",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Acta Physica Sinica (overseas Edition)",
        "year": 1999
    },
    "9anUsu3K": {
        "id": "9anUsu3K",
        "title": "Analysis on Characteristics of Runoff Time Series in Manas River,Xinjiang Province",
        "abstract": "Based on the monthly runoff data for 54 years of the Kenswatt hydrological station on Manas river,we studied the annual trend,abrupt change and future trend by making use of parametric test,nonparametric test,and R/S analysis,and the annual distribution characteristics of runoff were depicted by using several correlative indices.Results showed that the annual runoff changed abruptly at 1994,agreeing with the conclusion from analysis on the accumulative anomaly index;the Hurst coefficient of the annual runoff was 0.7747(H>0.5),indicating that the runoff was of persistence and would still keep an increasing trend;the annual runoff at the Kenswatt station mainly concentrated in summer(June-August),and the concentration degree was more discriminable and sensitive than the index of heterogeneity,and all the indices were correlative.",
        "keywords": [
            "time series analysis",
            "the Manas river",
            "heterogeneity",
            "runoff change"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi ,China"
            },
            {
                "name": "ZHANG Qing-qing",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Desert Research",
        "year": 2011
    },
    "Zv0zdWPH": {
        "id": "Zv0zdWPH",
        "title": "Design of Monitor for Storage Battery Maintenance and Testing System Based on LabVIEW",
        "abstract": "Storage Battery Maintenance and Testing System constitutes a network through CAN bus technology,which can achieve remote monitoring.Monitoring system,which is based on LabVIEW as a software development platform,can realize monitoring and analysis of battery data and charge or discharge parameters, as well as the control on the charge - discharge process.The paper that is based on introducing the system components,focus on analysis of the system applications of CAN protocol,as well as the interfaces design of LabVLEW with CAN bus and a database.",
        "keywords": [
            "charge or discharge parameters",
            "monitoring system",
            "CAN bus",
            "LabVIEW",
            "battery data"
        ],
        "authors": [
            {
                "name": "ZHANG Bin",
                "org": "College of Electrical Engineering,Beijing Jiao Tong University,Beijing,,China"
            },
            {
                "name": "JIANG Jiu-chun",
                "org": "College of Electrical Engineering,Beijing Jiao Tong University,Beijing,,China"
            },
            {
                "name": "NIU Li-yong",
                "org": "College of Electrical Engineering,Beijing Jiao Tong University,Beijing,,China"
            },
            {
                "name": "SHI Wei",
                "org": "College of Electrical Engineering,Beijing Jiao Tong University,Beijing,,China"
            }
        ],
        "venue": "Machinery & Electronics",
        "year": 2010
    },
    "2NlsKN2y": {
        "id": "2NlsKN2y",
        "title": "On the Critique of Lukacs' Theory of Materialization",
        "abstract": "Lukacs was strange as a western Marxism to represent in early days with the materialization theories and materialization consciousness for marking.this theory in inheriting Marx's theory,opening in the west Marxism new research direction,played the vital role.This article will attempt Lukacs materialization theory to set to the critique angle performs to understand that,namely from the economical critique,the philosophy critique and the cultural critique tertiary angle of view,careful will organize Lukacs materialization theory logical principle road,earnestly will excavate Lukacs materialization theory the thought special aim,thoroughly will comprehend his materialization theory critique thinking mode,will be able to enter his theory itself by the time.",
        "keywords": [
            "Alienation",
            "Materialization consciousness",
            "Materialization",
            "Work materialization"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Politics and Law,North-east Normal University,Changchun ,China"
            },
            {
                "name": "HAN Qiu-hong",
                "org": "School of Politics and Law,North-east Normal University,Changchun ,China"
            }
        ],
        "venue": "Journal of Inner Mongolia University for Nationalities(Social Sciences)",
        "year": 2006
    },
    "rZa8Qcci": {
        "id": "rZa8Qcci",
        "title": "A Review on the Psychology of Suicide Terrorism",
        "abstract": "Suicide terrorism refers to that someone actively and intentionally kills themselves along with the chosen innocent targets to meet with a success of the mission,in the service of catching the attention of the target objects or the public and creating an atmosphere of terror,and eventually achieving certain political,religious or social purposes.There is no single profile of the individual suicide terrorist.And their motivations are complex.Perhaps they are motivated by religious or political purpose,or it's the choice after rational analysis.The Quest-for-Significance Model is a comprehensive model that integrates all the levels of analysis and links related theories or views.There is not much difference of male and female suicide terrorists.But females may want to strive for gender equality.And they are more likely to be driven by personal causes.Because it's arduous for us to collect actual data and information of suicide terrorist,the conclusions may be speculative.In future we have to apply more other empirical approaches.",
        "keywords": [
            "psychological profile",
            "terrorism",
            "quest-for-significance",
            "motivation",
            "suicide"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            },
            {
                "name": "JIA Feng-Xiang",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2011
    },
    "oJ4wlaQh": {
        "id": "oJ4wlaQh",
        "title": "Temperature control properties of mass concrete with phase change material",
        "abstract": "Phase change materials (PCM) can be applied in mass concrete to prevent thermal cracks. Phase change material was added to fresh concrete when casting, latent heat in phase change material was released or absorbed in a certain temperature to control temperature in mass concrete. Temperature measurement system was designed to test temperature-control properties of PCM concrete. The results show that phase change material can reduce maximum temperature in concrete; furthermore, it can reduce temperature increase and decrease velocity so as to prevent thermal cracks in mass concrete.",
        "keywords": [
            "Mass concrete",
            "Phase change materials",
            "Temperature control",
            "Temperature cracks"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Tongji University(Tongji University,Tongji Univ.),Shanghai,China"
            },
            {
                "name": "Xiong Zhang",
                "org": "Tongji University(Tongji University,Tongji Univ.),Shanghai,China"
            },
            {
                "name": "Jürgen W. Dreyer",
                "org": "Technische Universitat Wien(Vienna University of Technology,Technische Universität Wien),Vienna,Austria"
            }
        ],
        "venue": "Tongji Daxue Xuebao/Journal of Tongji University",
        "year": 2010
    },
    "LerLHlQZ": {
        "id": "LerLHlQZ",
        "title": "Fault Analysis of the Wind Turbine Drive Train in the Quefrency Region",
        "abstract": "",
        "keywords": [
            "dynamics",
            "cepstrum",
            "drive train",
            "structural analysis"
        ],
        "authors": [
            {
                "name": "yonghui park",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "bjYPL9x4": {
        "id": "bjYPL9x4",
        "title": "Integrated tapered MMI couplers in the silicon-on-insulator technology",
        "abstract": "The authors have designed and fabricated 2/spl times/2 parabolically tapered MMI coupler with large cross-section and large space between difference ports using silicon-on-insulator (SOI) technology. The devices demonstrate a minimum uniformity of 0.8 dB and 30% shorter than the straight MMI coupler.",
        "keywords": [
            "2/spl times/2 parabolically tapered mmi coupler design",
            "large space",
            "difference ports",
            "light interference",
            "silicon-on-insulator technology",
            "optical fabrication",
            "silicon-on-insulator",
            "minimum uniformity",
            "2/spl times/2 parabolically tapered mmi coupler fabrication",
            "optical design techniques",
            "integrated optics",
            "optical couplers",
            "integrated tapered mmi couplers",
            "interference",
            "etching",
            "space technology",
            "silicon on insulator",
            "optical waveguides",
            "cross section"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhongli Liu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Hongzhi Ma",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Guohua Li",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Liangchen Wang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Lasers and Electro-Optics, 2001. CLEO/Pacific Rim 2001. The 4th Pacific Rim Conference",
        "year": 2001
    },
    "4h7O4ree": {
        "id": "4h7O4ree",
        "title": "A novel asynchronous on-chip router based on hierarchical bit-line buffer",
        "abstract": "Buffer resources are key components of the on-chip router,and their structures exert significant influence on the performance and power consumption of the interconnection network.In general,asynchronous FIFO based on shift registers is adopted to implement on-chip buffer resources.Packets transmitted traverse the FIFO queue step by step,leading to higher propagation delay of packets and larger transition counts in the circuit.In this research,an asynchronous FIFO based on hierarchical bit-line buffer is proposed,and then a new asynchronous on-chip router is presented in detail.Compared with the traditional asynchronous router,the newly presented one has lower hardware complexity and power consumption.Experiments show that the new router can achieve 39.3% area saving and 41.1% power reduction when the depth of asynchronous FIFO is configured with 8.",
        "keywords": [
            "Asynchronous circuit",
            "Hierarchical bit-line buffer",
            "Low power",
            "Network-on-chip"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "College of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "Yufeng Guo",
                "org": "National University of Defense Technology(National University of Defense Technology,National Univ. of Defense Technology),Changsha,China"
            },
            {
                "name": "WANG Lei",
                "org": "College of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "GONG Rui",
                "org": "College of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "Qiang Dou",
                "org": "National University of Defense Technology(National University of Defense Technology,National Univ. of Defense Technology),Changsha,China"
            }
        ],
        "venue": "Journal of National University of Defense Technology",
        "year": 2012
    },
    "qPJd8OAD": {
        "id": "qPJd8OAD",
        "title": "Study on non-invasive modeling approach of contraceptive rat with intrauterine device",
        "abstract": "Objective:To explore the contraceptive model of non-invasive insertion of intrauterine device (IUD) in rats.Methods:Fifty SD rat moms were assigned into non-invasive,invasive,non-invasive sham,invasive sham and blank control groups randomly.An copper-IUD was placed into the unilateral uterus through the vagina cervix way in the non invasive group and through the intraperitoneal uterus way in the invasive group.The IUD was removed immediately after the operation mentioned above was conducted in the non-invasive sham and the invasive sham groups.The sixth day after modeling,the successful rate of insertion,the expulsion rate,uterine morphological changes and concentrations of TXB 2 and 6-keto-PGF1α in the uterine flushing were evaluated.Results:The successful rates of insertion were all 100% in non-invasive,invasive and sham groups.The IUD expulsion rate of the noninvasive group was lower than that of the invasive group,while no significant difference was found (P > 0.05) .The peritoneal heterotopic was found in two rats.The extents of the uterine congestion and edema and the adhesion of abdominal organs in the non-invasive group were much less than those of the invasive group(P all < 0.05) .The concentrations of TXB 2 in the non-invasive group and the invasive group were significantly lower than that of the blank control group,while the concentrations of 6-keto-PGF1α were much higher (P < 0.01) .Endometrial epithelial defects,inflammatory cell infiltrates and scattered thrombus were obvious in the non-invasive group and the invasive group,especially in the site of IUD insertion of the invasive group.Conclusion:It is feasible to simulate clinical IUD insertion for contraception in the rat,and the rat model could be used for the study on side effects of IUD use And less damage on the endometrium with the non invasine approach is suggested.",
        "keywords": [
            "Rat",
            "Contraception",
            "Non-invasive modeling",
            "Intrauterine device",
            "Animal model"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": " 1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan "
            },
            {
                "name": "Xu Li",
                "org": "Affiliated Provincial Hospital of Shandong University"
            },
            {
                "name": "Liang Na",
                "org": " 1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan "
            },
            {
                "name": "Yue Hengxue",
                "org": " 1.Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan "
            }
        ],
        "venue": "Chinese Journal of Family Planning",
        "year": 2013
    },
    "DIV1ojA5": {
        "id": "DIV1ojA5",
        "title": "A retrospective analysis of catheter-related infections in 1028 critical cases with blood purification",
        "abstract": "Objective To explore the catheter-related infections in critical patients with blood purification. Methods This is a retrospective analysis conducted by the Intensive Care Unit of Guangdong General Hospital. All patients admitted to the ICU during the 2 years period from January 1, 2010 to December 30, 2011 and treated with continuous renal replacement therapy (CRRT) or intermittent hemodialysis (IHD) were included. Results A total of 1,028 patients were included in this study. The total number of catheterization and catheterization days were 1,123 times and 16,845 days, including jugular catheterization 215 times and 3,665 days, femoral catheterization 908 times and 13,580 days, respectively. The total number of catheterization and catheterization days were 918 times and 14,688 days, respectively, in CRRT group, and were 295 times and 2,157 days, respectively, in IHD group. The incidence of catheter-related local infection (CRLI) was statistically higher in catheterization patients using femoral route than in those using jugular route (4.79% vs 2.72%, P < 0.05), but was indifferent between patients with CRRT and those with IHD (4.43% and 4.63%, P > 0.05). The incidence of catheter related blood stream infection (CRBSI) was statistically higher in catheterization patients using femoral route than in those using jugular route (3.24% vs 1.64%, P<0.05), and was higher in patients with CRRT than those with IHD (3.13% and 1.85%, P < 0.05). Conclusion For critically ill patients required hemodialysis, blood access through internal jugular vein is preferable with the lower infection incidence than that through femoral vein. The incidence of CRBSI was higher in patients with CRRT than those with IHD. However, whether CRRT actually increases the CRBSI incidence needs to be further studied.",
        "keywords": [
            "Critically ill patient",
            "Catheter-related infection",
            "Blood purification"
        ],
        "authors": [
            {
                "name": "LIANG Hua-ban",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "LIANG Xin-ling",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "WANG Wen-jian",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "LI Zhi-lian",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "TAO Yi-ming",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "LI Rui-zhao",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "LIU Shuang-xin",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            },
            {
                "name": "SHI W",
                "org": "e. Nephrology Department, Guangdong General Hospital, Guangzhou"
            }
        ],
        "venue": "Chinese Journal of Blood Purification",
        "year": 2012
    },
    "j6V32bD7": {
        "id": "j6V32bD7",
        "title": "Managerial response to constitutional constraints on shareholder power",
        "abstract": "Research summary: We examine whether top managers engage in misconduct, such as illegal insider trading, illegal stock option backdating, bribery, and financial manipulation, in response to the presence, or absence, of governance provisions that impose constitutional constraints on shareholder power. Within the agency framework, shareholders typically oppose governance provisions that limit their power because those provisions could undermine shareholder influence and increase agency costs. However, when shareholders support provisions that constrain their power, managers could respond positively by refraining from self-interested behavior in the form of managerial misconduct. We find this to be especially true in industries where these governance provisions are particularly relevant to managers and in scenarios where CEOs do not also serve as board chair.Managerial summary: In recent years, shareholders have become central to organizations and the managers who run them. Shareholders and managers establish a rapport with one another, such that the behavior of one affects the behavior of the other. One of the most consequential decisions shareholders can make pertains to the reach of their influence: They can choose to impose strict governance over firms they own or they can allow for constitutional constraints that limit shareholder power. When they act in the mutual interest of managers by allowing such constraints, we find that managers respond in kind by refraining from bad behavior, such as illegal stock options backdating, insider trading, and financial manipulation. This is especially true in industries and scenarios in which shareholder pressure is most relevant to managers. Copyright © 2016 John Wiley u0026 Sons, Ltd.",
        "keywords": "",
        "authors": [
            {
                "name": "Brian L. Connelly",
                "org": "Raymond J. Harbert College of Business Auburn University Auburn Alabama U.S.A."
            },
            {
                "name": "Wei Shi",
                "org": "Kelley School of Business Indiana University Indianapolis Indiana U.S.A."
            },
            {
                "name": "Jinyong Zyung",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas U.S.A."
            }
        ],
        "venue": "Strategic Management Journal",
        "year": 2017
    },
    "2CkjIhq4": {
        "id": "2CkjIhq4",
        "title": "Power frequency and switching overvoltages of 750 kV AC transmission line",
        "abstract": "The overvoltages of 750 kV transmission line are more serious because of its long length, small surge impedance and large distributing capacitance, hence it is necessary to study the power frequency and switching overvoltages, which provides reasonable reference for insulation coordination. Combined with 750 kV power transmission project from Guanting to Xining which has been reasoned by State Power Grid Corp. of China, the relationship between the neutral reactance of three phase reactor and the secondary arc current was analyzed. The value of neutral reactance was selected, which ensured the success of single-phase auto-reclosing. The power frequency overvoltage and switching overvoltage, including three-phase closing with no load and single-phase auto-reclosing, were studied. The protective effects of shunt reactor, MOA and parallel resistor in CB (circuit breaker) on the overvoltages above were also discussed. Based on the studies above, with the altering of distributing capacitance and the length of the transmission line, the condition of removing the parallel resistor in CB is studied, which are compared with the practical results. From the theoretical analysis and simulated results of Electro Magnetic Transient Program (EMTP), it is shown that the power frequency overvoltage is under the concerned regulations of our country owing to the reactors connected to the line. Combining MOA and parallel resistor in CB is a good measure to limit switching overvoltage without such high requirement on thermal capacity of MOA and resistor. When eliminating closing resistor, MOA can work normally, but the magnitudes of switching overvoltage is too high to be against engineering request. For the distributing capacitance of 700 MW, the parallel resistor in CB could be removed if the line length is below 60 km. The arresters installed at both ends of the line could limit the overvoltages within the design allowable value. To meet the same regulation, the maximal length of the transmission line would be up to 380 km by installing another arrester along the line.",
        "keywords": [
            "750 kV",
            "Closing resistor",
            "EMTP",
            "MOA",
            "Power frequency overvoltage",
            "Switching overvoltage",
            "Transmission line"
        ],
        "authors": [
            {
                "name": "Qing Liu",
                "org": "Xi'an University of Engineering Science and Technology(Xi'an University of Science and Technology),Xi An,China"
            },
            {
                "name": "ZHANG Yu-feng",
                "org": "Xi'an University of Engineering Science and Technology(Xi'an University of Science and Technology),Xi An,China"
            },
            {
                "name": "Geng Wan",
                "org": "Xi'an University of Engineering Science and Technology(Xi'an University of Science and Technology),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2009
    },
    "hMfYnbXx": {
        "id": "hMfYnbXx",
        "title": "A Novel Flow for Asynchronous Circuit Design Using Synchronous EDA Tools",
        "abstract": "With the rapid development of VLSI technology and the great increase of application requirements,the synchronous circuit with global clock has encountered several crucial problems,such as great clock skew and high power dissipation.Heightened interest in low power consumption and growing concern over clock skew have encouraged the use of asynchronous techniques as a viable approach to future circuit design.But the wide acceptance of asynchronous circuits has been hindered by the lack of commercial EDA tools.Since current design methodologies are difficult for VLSI design and implementation,a novel design flow for asynchronous circuits is presented.By fully using conventional EDA tools,this flow can improve the efficiency and decrease the difficulties of design as well.To obtain optimized circuit structure,multi-virtual clock method is used for logic synthesis.The delay of asynchronous control path is also accurately matched through a quantitative analysis approach.Based on this flow,an asynchronous microprocessor core in UMC 0.18 μm process is designed and implemented.Experimental results show that this flow can make the design of asynchronous circuits easily and effectively,and the asynchronous circuit style can offer a low power solution for future microprocessor design.",
        "keywords": [
            "design flow",
            "asynchronous circuit",
            "synthesis optimization",
            "matched delay",
            "EDA tool"
        ],
        "authors": [
            {
                "name": "Wang Yourui",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Shi Wei",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Wang Zhiying",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Lu Hongyi",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "Su Bo",
                "org": "College of Computer,National University of Defense Technology,Changsha "
            }
        ],
        "venue": "Journal of Computer Research and Development",
        "year": 2012
    },
    "yYiki5yp": {
        "id": "yYiki5yp",
        "title": "Car security alarm system design based on PSoC",
        "abstract": "At present,vehicle security alarm devices commonly have limitation of false alarming rate and can not make effective communication between car and owner,a car security alarm system based on PSoC is designed.In this system,PSoC is used as main control chip,which achieves the goal of the single chip system,decreases the PCB area and reduces cost;in addition,this system uses GSM network to let owners know the car safety conditions in time,and at the same time,it uses SC—1 vibration sensor to improve the sensitivity of car security alarm system.These advantages solve problems of the false alarming rate and car-owner communication.Through actual simulation and test,it proves that this system performances steadily and has significant value.",
        "keywords": [
            "sensor",
            "PSoC",
            "GSM network"
        ],
        "authors": [
            {
                "name": "XU Li",
                "org": "School of Information Engineering,Taiyuan University of Technology, Taiyuan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Information Engineering,Taiyuan University of Technology, Taiyuan ,China"
            },
            {
                "name": "ZHAO Liang",
                "org": "School of Information Engineering,Taiyuan University of Technology, Taiyuan ,China"
            }
        ],
        "venue": "Transducer and Microsystem Technologies",
        "year": 2013
    },
    "4YZArNBo": {
        "id": "4YZArNBo",
        "title": "The complete mitochondrial genome sequence of Cynoglossus roulei (Pleuronectiformes: Cynoglossidae)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Shixi Chen",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Jiangxing Dong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Hairong Luo",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Xiaoyu Kong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2019
    },
    "oyPrfcbr": {
        "id": "oyPrfcbr",
        "title": "Shareholder Influence on Joint Venture Exploration",
        "abstract": "In this study, we theorize about how different types of institutional investors influence firms’ choice of exploration versus exploitation for their joint ventures (JVs). Exploratory JVs engender risk, uncertain outcomes, and ex post contractual updating, whereas exploitative JVs allow for ex ante contracts. We argue that dedicated institutional investors (DIIs), who maintain concentrated holdings over time regardless of current earnings, offer tolerance for failure and reward for long-term success that encourages managerial choice of exploratory JVs. Transient institutional investors (TIIs), who trade frequently based on near-term performance metrics, prefer ex ante contracts and use exit to discipline managers who do not meet their short-term performance objectives. This suggests that TIIs may influence managers to reduce the extent to which they choose exploratory (as opposed to exploitative) JVs. Furthermore, we argue that the transactional governance of TIIs gives way to the relational monitoring of ...",
        "keywords": "",
        "authors": [
            {
                "name": "Brian L. Connelly",
                "org": "Auburn University"
            },
            {
                "name": "Brian L. Connelly",
                "org": "Auburn University"
            },
            {
                "name": "Wei Shi",
                "org": "University of Miami"
            },
            {
                "name": "Wei Shi",
                "org": "University of Miami"
            },
            {
                "name": "Robert E. Hoskisson",
                "org": "Rice University"
            },
            {
                "name": "Balaji R. Koka",
                "org": ""
            }
        ],
        "venue": "Journal of Management",
        "year": 2018
    },
    "45zv6R3O": {
        "id": "45zv6R3O",
        "title": "A systematical method for suppressing ferroresonance at neutral-grounded substations",
        "abstract": "At neutral-grounded substations, ferroresonance may happen upon switching a circuit breaker or disconnector, due to the saturated magnetizing characteristics of the bus PT. In this paper, a systematical method is presented to analyze and suppress the phenomenon. The scheme for suppressing the ferroresonance is to insert resistance, made from parallel-connected resistors, into the PT's wye secondary circuit. For a particular substation, it is first studied theoretically whether ferroresonance can possibly happen; and if so, a theoretical critical resistance is estimated to avoid the resonance. A practical one is then achieved by EMTP simulation on the basis of the theoretical one. The scheme for switching these resistors out of the circuit is to do that not all at once, but rather, in turn, to avoid exciting ferroresonance again. The appropriate resistance value of the resistors and the schedule of switching them out are also determined by EMTP simulation. A prototype was developed to fulfill the scheme, and proved to be effective by field tests. In addition, it is demonstrated that this kind of ferroresonance cannot be suppressed by adding resistance to the PT's delta secondary circuit.",
        "keywords": [
            "Ferroresonance",
            "Substations",
            "Resistors",
            "Switching circuits",
            "EMTP",
            "Circuit simulation",
            "Magnetic switching",
            "Circuit breakers",
            "Saturation magnetization",
            "Magnetic analysis"
        ],
        "authors": [
            {
                "name": "Yunge Li",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": "E.E. Dept"
            },
            {
                "name": "Rui Qin",
                "org": ""
            },
            {
                "name": "Jilin Yang",
                "org": ""
            }
        ],
        "venue": "IEEE Transactions on Power Delivery",
        "year": 2003
    },
    "4A100WMh": {
        "id": "4A100WMh",
        "title": "TECTONIC DEFORMATION FEATURES OF SHENNONGJIA REGION IN EASTERN DABASHAN FORELAND STRUCTURAL BELT",
        "abstract": "Shennongjia is located in the eastern part of Dabashan foreland arc-shaped structural belt.With the Yangri fault as a boundary,this region can be divided into the northern and southern parts.The northern part is characterized by W-E trending basement-involved detachment and cover folding,with the Palaeozoic cover closely folded.The southern part,named Shennongjia basement uplift,has different deformation features in the periphery,with deformation weak in northern margin but strong in the eastern one.As to this uplift,there are skirtlike fold structures in its western and southern margins,and the southern ones were characterized by fold hinge with large plunge angle.From the field analysis of fault kinematics and paleo-tectonic stress inversion from slip vectors,we can see that the region was mainly controlled by S-N compression stress field,but the stress field of the eastern margin was changed into NW-SE because of the compression from Shennongjia and Huangling uplift.Regional structural analysis and comparison showed that the eastern part of Dabashan foreland structural belt experienced Indosian primary formation stage and Yanshan final formation stage, and the Shennongjia basement uplift played a role of restriction in the formation of Dabashan foreland arc-shaped structural belt.The research on the deformation of Shennongjia has great significance to understanding the formation and evolution of the Dabashan foreland arc-shaped structural belt.",
        "keywords": [
            "basement-involved detachment",
            "skirt-like fold structures",
            "Dabashan foreland structural belt",
            "tectonic stress fields",
            "Shennongjia basement uplift"
        ],
        "authors": [
            {
                "name": "LI Jian-hua",
                "org": "Key Laboratory of Neotectonic Movement & Geohazard,Ministry of Land and Resources,Beijing ,China;Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Yue-qiao",
                "org": "Key Laboratory of Neotectonic Movement & Geohazard,Ministry of Land and Resources,Beijing ,China;Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Key Laboratory of Neotectonic Movement & Geohazard,Ministry of Land and Resources,Beijing ,China;Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "LI Hai-long",
                "org": "Key Laboratory of Neotectonic Movement & Geohazard,Ministry of Land and Resources,Beijing ,China;Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "DONG Shu-wen",
                "org": "Chinese Academy of Geological Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Geomechanics",
        "year": 2009
    },
    "QXOlqLFU": {
        "id": "QXOlqLFU",
        "title": "Research on the development of fine motor function of upper limbs in children with hemiplegia",
        "abstract": "Objective To describe the patterns of fine motor development of both the affected and the contralateral upper limbs in children with spastic hemiplegia using nonlinear mixed effect model ( NONMEM) ,so as to further characterize the patterns of the fine motor development in children with spastic hemiplegia. Methods From 2000 to 2012,patients with congenital spastic hemiplegia were consecutively enrolled from 8 rehabilitation centers and 6 special education schools in Shanghai. Their fine motor functions were assessed with the fine motor function measure scale ( FMFM) for children with cerebral palsy ( CP) . Both the affected side and the contralateral side were assessed with FMFM,while the scores were analyzed respectively in the nonlinear mixed effect model. Two major parameters obtained from the model were used as clinical interpretations. The first parameter was 90% limits of fine motor function. The second was the age at which children were expected to achieve 90% limit of FMFM. Results A total of 536 children ( 360 male 67. 2% ,284 right hemiplegia 53.0% ,252 left hemiplegia 47.0% ) were enrolled in the study. The youngest child was 5 months old at first evaluation,the eldest 17.8 years old,and with average ( 3.4±3.2) years old. Altogether 792 pairs of FMFM scores were studied,1.48 pairs for each child. The average age for all 792 pairs of assessments was ( 4.1±3.8) years old. 73 children completed twice evaluations,while 54 completed three times or more. Stable limit model was used to fit the fine motor function model of the contralateral limb,while decline model was used to fit the model of the affected limb. Both models fit successfully. FMFM maximum score of the contralateral limb was 73.4,significantly higher than that of the affected limb,64.0. Age-90 was 2.7 years for the contralateral side and 3.3 years for the affected limb. After reaching the maximum,FMFM score of the affected limb began to decline and dropped 12% from the peak of 64.0 to 56.5. Conclusions The fine motor development limit of the affected limb was lower than that of the contralateral side. It took more time for the affected limb to reach its developmental limit and the score tended to drop after that. The training of fine motor functions for children with hemiplegia should be based on the different developmental features of both limbs.",
        "keywords": [
            "Evaluation",
            "Hemiplegia",
            "Fine motor",
            "Function",
            "Cerebral palsy",
            "Nonlinear mixed effect model",
            "Development",
            "Upper limbs"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "DING Jun-jie",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "SU Yi",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "HOU Fang-hua",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "WANG Yi",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "YU Jian",
                "org": " Rehabilitation Center of Children's Hospital of Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Pediatrics",
        "year": 2013
    },
    "CVXYDcJH": {
        "id": "CVXYDcJH",
        "title": "The Cenozoic tectonic evolution of the faulted basins in the northern margin of the Eastern Qinling Mountains, Central China: Constraints from fault kinematic analysis",
        "abstract": "Abstract   A series of NE and NW-trending Cenozoic faulted basins, located at the north margin of the Eastern Qinling Mountains, document Cenozoic intracontinental extension process in Central China. Based on fault kinematic analysis of the faulted basins, coupling with the stratigraphic sequence, we rebuilt a tectonic stress sequence of the faulted basins since the Cenozoic era. Combined with the previous chronological data, we define the Cenozoic faulted basin formation process including two stages of tectonic evolution. The first stage largely presents the NW-SE extensional rifting in a long period from the Paleocene to the Middle-Late Miocene due to northwestward subduction of the Pacific plate. It is marked by the basin occurrence along the north margin of the Eastern Qinling Mountains (e.g., the Sanmenxia, Lushi, Shangluo, and Weihe Basins) in the Paleocene to the Early-Middle Miocene in accordance with a NW-SE extension, and regional basin inversion in the Middle Miocene as the result of a NW-SE compression. The second stage is featured by the three-episode extension since the Middle-Late Miocene, which is probably affected by the combination of the northeastward growth of the Tibetan Plateau and the northwestward subduction of the Pacific Plate. The earliest episode of NW-SE extension caused by regional NE-SW compression in the Late Miocene to Early Pleistocene, which leads to the formation of the Yuncheng Basin. A gentle NE-SW extension subsequently dominated here in the Late Pleistocene, as represented by the widespread appearance of paleo-lakes in the basins. Then the youngest tectonic regime controlled this region, characteristic of a tectonic transpression (ENE-SWS compression and NNW-SSE extension), causing evidently strike-slip activities on the primary faults in the basins.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China"
            },
            {
                "name": "Long Chen",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China"
            },
            {
                "name": "Xingqiang Chen",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China"
            },
            {
                "name": "Min Cen",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China"
            },
            {
                "name": "Yu Zhang",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China"
            }
        ],
        "venue": "Journal of Asian Earth Sciences",
        "year": 2019
    },
    "OQIA7iWw": {
        "id": "OQIA7iWw",
        "title": "A Geopolitical Perspective into the Opposition to Globalizing State-Owned Enterprises in Target States",
        "abstract": "Existing studies on multinational enterprise (MNE) location strategy assume that MNEs are focused on economic not political objectives. The emergence of globalizing state-owned enterprises (SOEs) requires us to revisit such an assumption because SOEs symbolize national interests of their home states and are perceived as political entities by target states. This paper provides a geopolitical perspective into how geographic distance, religious similarity, and political regime similarity between two nation states, as well as resource complementarity between globalizing SOEs and target states, explain the level of opposition that globalizing SOEs face in target states, which in turn affect their abilities to exploit locational advantages globally. We also investigate how the salience of nationalist politics moderates the influence of these geopolitical factors on the level of opposition that globalizing SOEs face. Although our geopolitical model focuses on globalizing SOEs, this model may shed new light on understanding the role of geopolitics in affecting private MNEs’ location choices.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Rice University Jesse H. Jones Graduate School of Business Houston Texas U.S.A."
            },
            {
                "name": "Robert E. Hoskisson",
                "org": "Rice University Jesse H. Jones Graduate School of Business Houston Texas U.S.A."
            },
            {
                "name": "Yan Anthea Zhang",
                "org": "Rice University Jesse H. Jones Graduate School of Business Houston Texas U.S.A."
            }
        ],
        "venue": "Global Strategy Journal",
        "year": 2016
    },
    "nyDpYT3u": {
        "id": "nyDpYT3u",
        "title": "The Early Philosophical Humanism Spirit of Ancient Greece",
        "abstract": "The humanism spirit is an important orientation of philosophy and even in the human civilization,and this kind of humanism orientation originates from the philosophy of ancient Greece in the early period.The philosophers of ancient Greece in the early period called the caring that they themselves for this world in the universe as \"philosophy\",using their lives and wisdom all their lives to diligently pursue the truth of world,the kindness of morality,and the beauty of life.Their philosophical investigation involves directly with the human being itself,the resistance of human being against the externally natural ruling power and the realization for the living status of human being itself,and in the process of eternally pursuing the nature of other things,it deeply embodies the pursuit for the fate,the desire for the wisdom state,and the ambition for the multi-orientation of the humanity,having the profound connotation,which also has the magnificent reality significance for the development of western philosophy in aftrer several thousand years,especially for the resolution of the philosophical crisis today.In the early period of the ancient Greece,the achievements created by the philosophy indeed make them obtain the eternal loftiness in the history of human civilization.",
        "keywords": [
            "ancient Greece",
            "humanism spirit",
            "early-period philosophy"
        ],
        "authors": [
            {
                "name": "HAN Qiu-hong",
                "org": "School of Politics and Laws,Northeast Normal University,Changchun ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Politics and Laws,Northeast Normal University,Changchun ,China"
            }
        ],
        "venue": "Journal of Northeast Normal University",
        "year": 2006
    },
    "n5hxrvs2": {
        "id": "n5hxrvs2",
        "title": "Association of interleukin 17 / angiotensin II with refractory hypertension risk in hemodialysis patients.",
        "abstract": "Objective: The study was performed to investigate the association of interleukin 17 (IL 17) or angiotensin II (Ang II) with refractory hypertension risk in hemodialysis patients. Methods: Ninety hemodialysis patients were enrolled into this study, and those with hypertension were divided into two groups. The Easy-to-Control Hypertension group (ECHG) had fifty patients, while the refractory hypertension group (RHG) had forty patients. Twenty healthy individuals were recruited as the control group. IL17 and Ang II were determined using a human IL 17 / Ang II enzyme-linked immunosorbent assay kit. Serum IL 17 and Ang II concentrations in RHG patients were higher than those in ECHG patients. Results: Serum IL 17 and Ang II concentrations in both patient groups were higher than those in the control group. Linear regression analysis showed a positive correlation between IL 17 and Ang II. In multivariate regression analysis, we found that IL17 and Ang II were associated with refractory hypertension risk in hemodialysis patients. Conclusion: IL17 and Ang II were associated with refractory hypertension risk in hemodialysis patients. There was also a positive correlation between IL 17and Ang II.",
        "keywords": [
            "Interleukin 17",
            "Angiotensin II",
            "refractory hypertension",
            "hemodialysis"
        ],
        "authors": [
            {
                "name": "Zebin Wang",
                "org": "Southern Med Univ, Guangzhou, Guangdong, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Guangdong Acad Med Hosp, Guangdong Gen Hosp, Dept Nephrol, Guangzhou, Guangdong, Peoples R China"
            },
            {
                "name": "Xinling Liang",
                "org": "Guangdong Acad Med Hosp, Guangdong Gen Hosp, Dept Nephrol, Guangzhou, Guangdong, Peoples R China"
            },
            {
                "name": "Wenjian Wang",
                "org": "Guangdong Acad Med Hosp, Guangdong Gen Hosp, Dept Nephrol, Guangzhou, Guangdong, Peoples R China"
            },
            {
                "name": "Jianbo Liang",
                "org": "GuangZhou Med Univ, Affiliated Hosp 2, Dept Nephrol, Guangzhou, Guangdong, Peoples R China"
            }
        ],
        "venue": "AFRICAN HEALTH SCIENCES",
        "year": 2016
    },
    "5p6K9Oqy": {
        "id": "5p6K9Oqy",
        "title": "Research on the Application of Blackboard System Structure in C4ISR",
        "abstract": "This paper introduces the C4ISR system and blackboard system structure,and expounds the application methods of blackboard system structure in self-campaign unit and among the neighbor-campaign units in the C4ISR.",
        "keywords": [
            "blackboard system structure",
            "C4ISR",
            "Hash table"
        ],
        "authors": [
            {
                "name": "WANG Qun-hui",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "3wlFWQVI": {
        "id": "3wlFWQVI",
        "title": "Ocean acidification increases the accumulation of titanium dioxide nanoparticles (nTiO 2 ) in edible bivalve mollusks and poses a potential threat to seafood safety.",
        "abstract": "Large amounts of anthropogenic CO in the atmosphere are taken up by the ocean, which leads to 'ocean acidification' (OA). In addition, the increasing application of nanoparticles inevitably leads to their increased release into the aquatic environment. However, the impact of OA on the bioaccumulation of nanoparticles in marine organisms still remains unknown. This study investigated the effects of OA on the bioaccumulation of a model nanoparticle, titanium dioxide nanoparticles (nTiO), in three edible bivalves. All species tested accumulated significantly greater amount of nTiO in pCO-acidified seawater. Furthermore, the potential health threats of realistic nTiO quantities accumulated in bivalves under future OA scenarios were evaluated with a mouse assay, which revealed evident organ edema and alterations in hematologic indices and blood chemistry values under future OA scenario (pH at 7.4). Overall, this study suggests that OA would enhance the accumulation of nTiO in edible bivalves and may therefore increase the health risk for seafood consumers.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Cheng Guo",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Xinguo Zhao",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Yichen Wang",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, P.R. China. guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "Scientific reports",
        "year": 2019
    },
    "b8VijO4h": {
        "id": "b8VijO4h",
        "title": "THz interferometer and its application on index of refraction measurement",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "xianjin shao",
                "org": ""
            },
            {
                "name": "quansheng feng",
                "org": ""
            },
            {
                "name": "lei hou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "BjPWKjli": {
        "id": "BjPWKjli",
        "title": "Design, Synthesis, and Pharmacological Characterization of N-(4-(2 (6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)yl)ethyl)phenyl)quinazolin-4-amine Derivatives: Novel Inhibitors Reversing P-Glycoprotein-Mediated Multidrug Resistance.",
        "abstract": "P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) is a principal obstacle for successful cancer chemotherapy. A novel P-gp inhibitor with a quinazoline scaffold, 12k, was considered to be the most promising for in-depth study. 12k possessed high potency (EC = 57.9 ± 3.5 nM), low cytotoxicity, and long duration of activity in reversing doxorubicin (DOX) resistance in K562/A02 cells. 12k also boosted the potency of other MDR-related cytotoxic agents with different structures, increased accumulation of DOX, blocked P-gp-mediated Rh123 efflux, and suppressed P-gp ATPase activity in K562/A02 MDR cells. However, 12k did not have any effects on CYP3A4 activity or P-gp expression. In particular, 12k had a good half-life and oral bioavailability and displayed no influence on DOX metabolism to obviate the side effects closely related to increased plasma concentrations of cytotoxic agents in vivo.",
        "keywords": "",
        "authors": [
            {
                "name": "Qianqian Qiu",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Baomin Liu",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Jian Cui",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Zheng Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Xin Deng",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Hao Qiang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Jieming Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Chen Liao",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Bo Zhang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Miaobo Pan",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Wenlong Huang",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University , Nanjing 210009, PR China."
            },
            {
                "name": "Hai Qian",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University , Nanjing 210009, PR China."
            }
        ],
        "venue": "Journal of medicinal chemistry",
        "year": 2017
    },
    "FmX5aLJ9": {
        "id": "FmX5aLJ9",
        "title": "Perovskite KNi0.1Co0.9F3 as pseudocapacitive conversion anode for high-performance nonaqueous Li-ion capacitors and dual-ion batteries",
        "abstract": "Perovskites K–Ni–Co–F (denoted as KNCF) with various Ni/Co ratios have been introduced as high-performance anodes for nonaqueous Li-ion capacitors (LICs) and dual-ion batteries (DIBs). The optimal KNCF (Ni/Co = 1-6) material possesses the stoichiometric formula of KNi0.1Co0.9F3 with cubic nanocrystal morphology and hierarchical porous structure. The KNCF (1-6) electrode shows a typical surface conversion reaction mechanism with a synergistic contribution of Ni and Co electroactive species for Li-ion storage. The KNCF (1-6)//activated carbon (AC) LIC with the anode precharged (or prelithiated) exhibits much higher energy/power densities and cycling stability than the non-precharged one, moreover, the overall performance is better than those of the KNCF (1-0)//AC and KNCF (0-1)//AC LICs. Interestingly, the constructed KNCF (1-6)//AC + LiFePO4 (LFP) (1 : 1) LIC exhibits better performance than the KNCF (1-6)//AC LIC by using a capacitor–battery hybrid cathode with higher specific capacity, and the performance of the KNCF (1-6)//AC LIC is also enhanced by the precharging treatment of both the KNCF (1-6) anode and AC cathode. The designed KNCF (1-6)//graphite (918) DIB exhibits better performance than the other three DIBs with the 918 + AC (1 : 1), 918 + LFP (1 : 1) and 918 + AC + LFP (1 : 1 : 1) cathodes. Furthermore, the designed LICs and DIBs also show a remarkable behavior at low (−20 °C) and high (40 °C) temperatures.",
        "keywords": "",
        "authors": [
            {
                "name": "Qilei Xu",
                "org": ""
            },
            {
                "name": "Rui Ding",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Danfeng Ying",
                "org": ""
            },
            {
                "name": "Yongfa Huang",
                "org": ""
            },
            {
                "name": "Tong Yan",
                "org": ""
            },
            {
                "name": "Xiujuan Sun",
                "org": ""
            },
            {
                "name": "Ping Gao",
                "org": ""
            },
            {
                "name": "Enhui Liu",
                "org": ""
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2019
    },
    "nxcYqybQ": {
        "id": "nxcYqybQ",
        "title": "The influence of low calcium dialysate on left ventricular diastolic function in peritoneal dialysis patients.",
        "abstract": "Left ventricular (LV) diastolic function was found to be a significant predictor of cardiovascular events and general mortality in dialysis. Studies have indicated that dialysate calcium concentrations were significantly associated with cardiac function. However, the relationship between low calcium dialysate and LV diastolic function has not been clear. The aim of this study was to investigate the influence of low calcium dialysate on cardiac function in peritoneal dialysis (PD) patients. A total of 60 PD patients were enrolled in this study, with a calcium content of the PD solution of 1.25 mmol/L in 30 patients (low-calcium group) and 1.75 mmol/L in 30 patients (standard-calcium group). Standard M-mode and two-dimensional ultrasound measurements were applied to detect the cardiac function. After 12-month follow-up, we found no significant difference in blood pressure, calcium, phosphorus, parathyroid hormone (PTH), etc., between the two groups. Residual renal function (RRF), which is associated with LV cardiac function, was significantly decreased in the standard-calcium group compared with the low-calcium group (5.64 ± 3.23 vs. 9.38 ± 3.17, p = .001). Compared with the low-calcium group, E (peak early diastolic velocity) and A (peak late diastolic velocity) were significantly decreased (p < .05), whereas myocardial performance index (MPI) was obviously increased in standard-calcium group (9.69 ± 2.71 vs. 7.75 ± 0.93, p < .05). In conclusion, our data suggest that low calcium dialysate treatment is significantly associated with better LV diastolic function.",
        "keywords": [
            "Low calcium dialysate",
            "cardiovascular disease",
            "diastolic dysfunction",
            "peritoneal dialysis",
            "residual renal function"
        ],
        "authors": [
            {
                "name": "Zebin Wang",
                "org": "c Department of Nephrology , The Second Affiliated Hospital of Guangzhou Medical University , Guangzhou , China."
            },
            {
                "name": "Yueqiang Wen",
                "org": "c Department of Nephrology , The Second Affiliated Hospital of Guangzhou Medical University , Guangzhou , China."
            },
            {
                "name": "Jianbo Liang",
                "org": "c Department of Nephrology , The Second Affiliated Hospital of Guangzhou Medical University , Guangzhou , China."
            },
            {
                "name": "Xinling Liang",
                "org": "b Division of Nephrology , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China."
            },
            {
                "name": "Wei Shi",
                "org": "b Division of Nephrology , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , China."
            }
        ],
        "venue": "Renal failure",
        "year": 2016
    },
    "ABZdhy8M": {
        "id": "ABZdhy8M",
        "title": "Overvoltage protection of inductors in 10 kV parallel reactive power compensating devices",
        "abstract": "In power system, when parallel reactive power compensating devices are switched, overvoltage often occurs, which causes damage to inductors and operating problems to shunt capacitors. In this paper, the overvoltage occurred when shunt capacitors are removed or switched in a 10 kV power system are calculated, and the effectiveness of using shunt resistor and gap to mitigate overvoltage is studied.",
        "keywords": [
            "EMTP",
            "Inductor",
            "Overvoltage",
            "Reactive power compensation",
            "Shunting resistor"
        ],
        "authors": [
            {
                "name": "WANG Hong-bin",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "LU Xu-chen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "AN Zong-gui",
                "org": "Xianyang Power Supply Bureau(Xianyang Power Supply Bureau,Xianyang Meteorological Bureau,Xian Yang Power Supply Bureau,Xianyang Electric Power Company,Xianyang Power Bureau,Xianyang Power Supply Bur.),Xinyang,China"
            }
        ],
        "venue": "Gaoya Dianqi/High Voltage Apparatus",
        "year": 2006
    },
    "HpeJYcTz": {
        "id": "HpeJYcTz",
        "title": "Advantages of oriented clinical practice of TCM undergraduates",
        "abstract": "Objective To train qualified clinical-oriented talents.Methods The content of clinical practice was determined for clinical-oriented practice and training professional TCM talents based on a full investigation and advanced disciplines of Chinese internal medicine.Results The students have learnt the diagnosis and treatment of common and frequently-occurring diseases,known well the emergency measures of severe cases,comprehended national academic development and dealt independently with common and frequently-occurring diseases.The oriented training method was reviewed favourably by teachers and students.The employment rate of graduated students was improved obviously.Conclusion The clinical practice plan is regulated for a part of TCM undergraduates to clinical-oriented practice and meet the needs of all-level hospitals in Guangxi area.",
        "keywords": [
            "clinical-oriented practice plan",
            "medical students",
            "TCM regular course"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "First Clinical Faculty,Guangxi Traditional Chinese Medicine University,Nanning "
            },
            {
                "name": "XIE Li-ping",
                "org": "First Clinical Faculty,Guangxi Traditional Chinese Medicine University,Nanning "
            },
            {
                "name": "TANG Jia-xing",
                "org": "First Clinical Faculty,Guangxi Traditional Chinese Medicine University,Nanning "
            },
            {
                "name": "LI Min-zhi",
                "org": "First Clinical Faculty,Guangxi Traditional Chinese Medicine University,Nanning "
            }
        ],
        "venue": "Education of Chinese Medicine",
        "year": 2010
    },
    "7d5UAgVM": {
        "id": "7d5UAgVM",
        "title": "Hybrid Working Mode of the GaAs Photoconductive Semiconductor Switch",
        "abstract": "Double peaks phenomenon of approximate rectangular wave was observed with the biased voltage increasing to a threshold for the cascade combination(double layer) semi-insulating(SI) GaAs photoconductive semiconductor switch(PCSS) in experiment. With the increase of biased voltage,the rise time nearly kept a constant,the width and fall time decreased slightly,and the double peaks increased obviously. The unique experimental phenomenon was continued in the cascade combination PCSS,the transmission characteristics for the combination SI GaAs PCSS were entirely different from the ordinary single(monolayer) switch. The cascade combination and single switch respectively operated in a different mode,the hybrid mode of the combination switch lied in between photoactivated charge domain(PACD) mode and the limit space charge accumulate(LSA) mode,nonlinear mode(which is also called lock-on or high gain mode) was inhibited in the hybrid mode. PACD mode and lock-on effect was displayed typically in the ordinary SI GaAs PCSS.",
        "keywords": [
            "photoactivated charge domain(PACD) mode",
            "hybrid mode",
            "GaAs photoconductive semiconductor switch(PCSS)",
            "limit space charge accumulation(LSA) mode"
        ],
        "authors": [
            {
                "name": "MA Xiang-rong",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "XIANG Mei",
                "org": ""
            }
        ],
        "venue": "Research and Exploration in Laboratory",
        "year": 2013
    },
    "GiPpfb7i": {
        "id": "GiPpfb7i",
        "title": "Bovine parathyroid hormone enhances osteoclast bone resorption by modulating V-ATPase through PTH1R.",
        "abstract": "The vacuolar-type H+ adenosine triphosphatase (V-ATPase) plays an important role in cellular acidification and bone resorption by osteoclasts. However, the direct effect of bovine parathyroid hormone (bPTH) on V-ATPase has not yet been elucidated. The aim of the present study was to assess the effects of bPTH on V-ATPase and osteoclasts. Osteoclasts from bone marrow (BM)-derived monocytes of C57BL/6 mice were cultured with or without bPTH. The mRNA and protein expression levels of the V-ATPase a3-subunit and d2-subunit (by RT-qPCR and western blot analysis), V-ATPase activity (using the V type ATPase Activity Assay kit) and the bone resorption function of osteoclasts (by bone resorption assay) were examined following treatment with various concentrations of bPTH (0.1, 1.0, 10 and 100 ng/ml) alone or with bPTH and its inhibitor, bafilomycin A1. Furthermore, the expression of parathyroid hormone (PTH) receptors in osteoclasts was also detected. The results revealed that the mRNA and protein expression levels of V-ATPase a3-subunit and d2-subunit increased in a dose‑dependent manner, paralleling the level of bPTH present. In addition, an increase in the concentration of bPTH was accompanied by the increased resorption capability of osteoclasts, whereas bone resorption was inhibited in the presence of bafilomycin A1. In addition, we confirmed the existence of parathyroid hormone 1 receptor (PTH1R) in osteoclasts using three different methods (RT-qPCR, western blot analysis and immunofluorescence staining). We found that bPTH enhanced the bone resorption capability of osteoclasts by modulating the expression of V-ATPase subunits, intracellular acidification and V-ATPase activity. Thus, we propose that PTH has a direct effect on osteoblasts and osteoclasts, and that this effect is mediated through PTH1R, thus contributing to bone remodeling.",
        "keywords": [
            "oncology",
            "apoptosis",
            "molecular medicine",
            "cell",
            "cell cycle",
            "gene",
            "cancer"
        ],
        "authors": [
            {
                "name": "Shuangxin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Weiping Zhu",
                "org": "Department of Nephrology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong 519000, P.R. China."
            },
            {
                "name": "Sijia Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Jianchao Ma",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Huitao Zhang",
                "org": "Department of Nephrology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong 519000, P.R. China."
            },
            {
                "name": "Zhonghe Li",
                "org": "Department of Nephrology, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong 519000, P.R. China."
            },
            {
                "name": "Li Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Bin Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Zhuo Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            }
        ],
        "venue": "International journal of molecular medicine",
        "year": 2015
    },
    "HO9s92Ql": {
        "id": "HO9s92Ql",
        "title": "Thermally stable guest-host polyetherketone poled polymer for electro-optical applications",
        "abstract": "The high glass transition temperature polymer polyetherketone doped with disperse red 13 (DR13/PEK-c) has been prepared by the spin-coating method. Through in situ second-harmonic generation, the corona poling temperature was optimized by measuring the temperature dependence of the in situ second-harmonic generation signal intensity under the poling electric field. The linear electro-optic coefficients of the poled polymer films have been determined at 632.8 nm by using a simple interferometric technique. The polymer system was measured after 13000 h, and found that it remained at 80% of its initial value.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Pan Qi-Wei",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Fang Chang-Shui",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qin Zhi-Hui",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Gu Qing-Tian",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wu Xiang-Wen",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Yu Jin-Zhong",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2002
    },
    "I5LQfrX6": {
        "id": "I5LQfrX6",
        "title": "One-step Synthesis and Enhanced Thermoelectric Properties of Polymer - Quantum Dot Composite Films.",
        "abstract": "Conventional syntheses of polymer-inorganic composite thermoelectric materials suffer major problems such as inhomogeneity, large particle size, and oxidation that result in ineffective loading. Now a one-step synthesis can be used to fabricate high-quality small-sized anions codoped poly(3,4-ethylenedioxythiophene):dodecylbenzenesulfonate/Cl-tellurium (PEDOT:DBSA/Cl-Te) composite films using a series of novel Te-IV-based oxidants. The synchronized production of PEDOT and Te results in thick and homogeneous films containing evenly distributed and well-protected Te quantum dots. Owing to the heavily doped crystalline polymer matrix as well as the <5nm unoxidized Te quantum dot loading, at low Te concentrations as 2.1-5.8wt%, the films exhibits high power factors of about 100Wm(-1)K(-2), which is 50% higher compared to a pure PEDOT:DBSA film.",
        "keywords": [
            "conducting polymers",
            "energy conversion",
            "nanocomposites",
            "polymerization",
            "quantum dots"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Hongyi Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Yanling Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "ANGEWANDTE CHEMIE-INTERNATIONAL EDITION",
        "year": 2018
    },
    "RW0mQCV5": {
        "id": "RW0mQCV5",
        "title": "Geothermochronology of Mo-W deposits in Balkhash metallogenic belt, Kazakhstan, Central Asia",
        "abstract": "The Balkhash metallogenic belt in Kazakhstan, with many porphyritic Cu-Mo deposits and some quartz-vein greisen Mo-W deposits, is a famous porphyritic Cu-Mo metallogenic belt in Central Asian metallogenic domain. Three typical Mo-W deposits such as East Kounrad, Akshatau, and Zhanet, are studied in this paper through the application of geothermochronology. Zircon SHRIMP U-Pb geochronology yields ages of 293.6±2.7 Ma (alkaline granite), 306±1 Ma (granodiorite), and 304±4 Ma (porphyry monzonite), for East Kounrad, Akshatau, and Zhanet deposits respectively, belonging to the tectonic-magmatism in the Late Hercynian. 40Ar/ 39Ar thermochronology gives the cooling ages at 292±3 Ma for biotite from Akshatau, and 288.8±3.6 Ma and 278±5 Ma for K-feldspars from Akshatau and East Kounrad, respectively. Apatite fission track dating of granitoids gives low temperature cooling ages of 92.1±5.7 Ma, 92.2±5.0 Ma and 80.3±4.9 Ma, for East Kounrad, Akshatau, and Zhanet deposits, respectively, suggesting the uplifting and exhumation of Mo-W deposits together with the granitoids during the Late Cretaceous. The geochronological data and thermal history modeling presented in this paper, together with metallogenic information from previous studies, reveal the entire thermo-history, from the intrusion of plutons and Mo-W metallogenesis in the abyssal system in the Late Carboniferous and the Early Permian, through regional cooling, to the exhumation of the deposits in the Late Cretaceous, in the western part of Balkhash metallogenic belt.",
        "keywords": [
            "40Ar/ 39Ar",
            "Balkhash metallogenic belt",
            "Fission track",
            "Geochronology",
            "Mo-W deposit",
            "SHRIMP U-Pb"
        ],
        "authors": [
            {
                "name": "CHEN Xuan-hua",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "CHEN Zheng-le",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "HAN Shu-qin",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "WANG Zhi-hong",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Yi Yang",
                "org": "Xinjiang Bureau of Geological Exploration(Xinjiang Bureau of Geological Exploration),Urumqi,China"
            },
            {
                "name": "YE Bao-ying",
                "org": "China University of Geosciences(China University of Geosciences),Wuhan,China"
            },
            {
                "name": "Li Xue-zhi",
                "org": "Xinjiang Bureau of Geological Exploration(Xinjiang Bureau of Geological Exploration),Urumqi,China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Yong Li",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Wen Chen",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            }
        ],
        "venue": "Diqiu Kexue - Zhongguo Dizhi Daxue Xuebao/Earth Science - Journal of China University of Geosciences",
        "year": 2012
    },
    "LNQm7j9l": {
        "id": "LNQm7j9l",
        "title": "Investigation of the new guest-host polyetherketone poled polymer",
        "abstract": "",
        "keywords": [
            "Polymer"
        ],
        "authors": [
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory, Institute of Crystal Materials,Shandong University,Jinan,People's Republic of China"
            },
            {
                "name": "Wei Shi",
                "org": "State Key Laboratory, Institute of Crystal Materials,Shandong University,Jinan,People's Republic of China"
            },
            {
                "name": "Qingtian Gu",
                "org": "State Key Laboratory, Institute of Crystal Materials,Shandong University,Jinan,People's Republic of China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "State Key Laboratory, Institute of Crystal Materials,Shandong University,Jinan,People's Republic of China"
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory, Institute of Crystal Materials,Shandong University,Jinan,People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors,Academia Sinica,Beijing,People's Republic of China"
            }
        ],
        "venue": "Journal of Materials Science Letters",
        "year": 2001
    },
    "Rq3choIZ": {
        "id": "Rq3choIZ",
        "title": "A Study on the Driving Cycle for the Life Test of Traction Battery in Electric Buses",
        "abstract": "Based on the operation data of electric buses,a method of analyzing the character of driving cycle for traction battery is proposed.With this method,the power distribution during driving process of electric bus is comprehensively analyzed first.Then principal components analysis technique is used to verify the correlation between test driving cycle and the main characteristic quantities of sample population.Finally life tests are conducted on LiMn2O4 battery with three different test cycles(constant current constant voltage,dynamic stress test and simplified Beijing dynamic stress test) respectively.The results show that varied power distributions and power durations cause different effects on the capacity fading rate of battery and the proposed simplified dynamic test cycle provides a basis for accurately predicting the lifespan of traction batteries.",
        "keywords": [
            "electric buses",
            "principal components analysis",
            "power distribution",
            "battery lifespan"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Jiang Jiuchun",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Zhang Weige",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Li Xue",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Jiang Jun",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Jia Rongda",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            }
        ],
        "venue": "Automotive Engineering",
        "year": 2013
    },
    "tLlJquPK": {
        "id": "tLlJquPK",
        "title": "Gross Motor Function and Manual Ability Classification in 4～12 Year Old Children with Cerebral Palsy of Different Types",
        "abstract": "Objective To explore the distribution and correlation of gross motor function and manual ability in 4~12 year old children with cerebral palsy of different types.Methods143 children with cerebral palsy(CP)were recruited according to the inclusion and exclusion criterions.They were assessed with Chinese version of Gross Motor Function Classification System(GMFCS)and Manual Ability Classification System(MACS).ResultsThe classification of GMFCS and MACS was Ⅰ~Ⅱ in 33(60.0%)children with spastic diplegia;Ⅲ~Ⅴ in 28(75.7%)children with spastic quadriplegia;Ⅰ in 21(55.3%)children with spastic hemiplegia,and GMFCS Ⅱ in 2 children,MACS Ⅱ in 14 children.There was moderate correlation between GMFCS and MACS(r=0.67,P<0.05).ConclusionGMFCS and MACS can be used to determine the gross motor function and manual ability in CP children of different types.",
        "keywords": [
            "manual ability",
            "classification",
            "cerebral palsy(CP)",
            "gross motor"
        ],
        "authors": [
            {
                "name": "YANG Hong",
                "org": ",et al.Child Rehabilitation Department,Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Child Rehabilitation Department,Children's Hospital of Fudan University,Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": ",et al.Child Rehabilitation Department,Children's Hospital of Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Rehabilitation Theory and Practice",
        "year": 2009
    },
    "7xS7zj6Z": {
        "id": "7xS7zj6Z",
        "title": "ITSGrid: A Novel Integrated Intelligent Transportation Information and Service Platform",
        "abstract": "With increasing demands of effective and efficient transportation from our society, the transportation issue has become a noticeable obstacle to the economic development for all countries and regions to a great extend. ITS (Intelligent Transportation Systems) technology is brought forward and considered as an effective approach that promises to alleviate many transportation problems such as traffic congestion, high accident rate, air pollution, and improve safety and reliability on existing roadway system. However, current ITS architectures do not give proper answers to some important problems in ITS such as how to integrate heterogeneous data on the semantic level, how to manage dynamic business process, how to cooperate ITS subsystems among different domains, how to communicate among traffic control center and road sensor network, etc. Hence, a fundamental shift in approach is needed to effectively resolve these complex problems.Fortunately, Grid technology, Semantic Web technology, Web Service technology, Messaging Oriented Middleware (MOM) technology bring us great chance to build a integrated platform for ITS to solve the beforementioned issues. Grid Computing is an ideal technology to realize resource sharing in distributed heterogeneity environments. Semantic Web offers a great opportunity to support data semantization based on a domain-specific ontology database. Process coordination based on Web Service gives a unified way to cooperate ITS subsystems among different organizations. Messaging Oriented Middleware enables distributed communication that is loosely coupled, reliable, and asynchronous in complex network environment.In this paper, we explore four technologies to build a novel Integrated Intelligent Transportation Information and Service Platform to realize traffic data semantization, traffic resource sharing, cooperation traffic process As a result, a key project for ITISP, ITSGrid, was started up by Zhejiang University and Hangzhou Enjoyor Electronics Co. Ltd in 2005. ITSGrid is an undergoing joint engineering project designed and developed by CCNT Lab in Zhejiang University and Enjoyor Electronics. The new features of ITSGrid are originated from two important research projects - DartGrid and DartFlow, and one key engineering project - JTang Application Server, in CCNT Lab. Its goal is to build intelligent transportation information and service platform, to integrate traffic data resources collected by Enjoyor and cooperate existing ITS subsystems and services deployed by Enjoyor, finally serve for transportation construction in China.",
        "keywords": [
            "web service technology",
            "semantic web technology",
            "messaging oriented middleware",
            "ideal technology",
            "traffic congestion",
            "service platform",
            "novel integrated intelligent transportation",
            "cooperation traffic process",
            "zhejiang university",
            "ccnt lab",
            "grid technology",
            "middleware",
            "process management",
            "application server",
            "air pollution",
            "sensor network",
            "semantic web",
            "business process",
            "web service",
            "transportation problem",
            "economic development",
            "complex network",
            "grid computing",
            "message oriented middleware",
            "resource sharing"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Shuiguang Deng",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Li Kuang",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Huajun Chen",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "DongCai Shi",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Zhao Xu",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Zhiyong Ye",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Zhaohui Wu",
                "org": "Zhejiang University, Hangzhou, P. R. China"
            },
            {
                "name": "Xiaohong Qian",
                "org": "Hangzhou Enjoyor Electronics Co., Ltd, Xidoumen Sci-tech Industrial Park, China"
            },
            {
                "name": "Xiuhai Chen",
                "org": "Hangzhou Enjoyor Electronics Co., Ltd, Xidoumen Sci-tech Industrial Park, China"
            },
            {
                "name": "Quanming Xu",
                "org": "Hangzhou Enjoyor Electronics Co., Ltd, Xidoumen Sci-tech Industrial Park, China"
            },
            {
                "name": "Feihu Chen",
                "org": "Hangzhou Enjoyor Electronics Co., Ltd, Xidoumen Sci-tech Industrial Park, China"
            }
        ],
        "venue": "IEEE SCC",
        "year": 2006
    },
    "yXJm8gIi": {
        "id": "yXJm8gIi",
        "title": "Signal bandwidth of general N × N multimode interference couplers",
        "abstract": "Analytical expression of signal bandwidth of general straight and tapered N/spl times/N multimode interference (MMI) couplers is presented. The signal bandwidth is characterized as a function of mode relative energy, mode propagation delay time, and mode pulse broadening in the multimode section of MMI coupler. The model is used to evaluate the signal bandwidth of specific couplers. Results indica...",
        "keywords": [
            "Bandwidth",
            "Interference",
            "Optical devices",
            "Optical crosstalk",
            "Optical interferometry",
            "Optical waveguides",
            "Optical fiber couplers",
            "Optical waveguide components",
            "Integrated optics",
            "Wavelength division multiplexing"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Inst. of Semicond., Acad. Sinica, Beijing, China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhongli Liu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Journal of Lightwave Technology",
        "year": 2001
    },
    "kgqt2swV": {
        "id": "kgqt2swV",
        "title": "Temporal-spatial Evolution of Stream Construction and Its Driving Forces in Manas River Basin During 1958-2006",
        "abstract": "This paper analyzes dynamic changes of length,density,branching ratio,length ratio and fractal dimension of the river networks and their driving factors based on the visual interpre-tation of remote sensing image of Manas River Basin during 1958,1976,1987 and 2006 by using the software of Arc/Info.In the results,the changes of the river networks obey Horton’s law,with geometric changes of stream number and average length and with continuous increase of river den-sity,length ratio and branching ratio.River density of oases in the basin is higher than that in the southern mountainous areas and the northern deserts.This is determined by the eco-environment,social-economic,synconditions,integrated development and ecological restoration in those areas.The increase of water quantity,population,and areas of cultivated lands and oases are the main driving factors.The expansion of cultivated land and oases is limited by water carrying capacity,therefore,it will become the key tasks to make rational plans for oases,to optimize river system structure and to improve water use efficiency.",
        "keywords": [
            "temporal-spatial dynamics",
            "Horton law",
            "driving factor",
            "Manas River Basin",
            "structure of river system"
        ],
        "authors": [
            {
                "name": "LING Hongbo",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "XU Hailiang",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China"
            },
            {
                "name": "QIAO Mu",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China"
            },
            {
                "name": "FAN Zili",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "ZHANG Qingqing",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Progress in Geography",
        "year": 2010
    },
    "W5Fv8Ukc": {
        "id": "W5Fv8Ukc",
        "title": "Methodology of Asynchronous Integrated Circuit Design-a Survey",
        "abstract": "Asynchronous circuits have drawn increasing attentions from not only researchers in universities but also designers in corporations for their advantages in terms of no clock skew,high modularity,low power and better EMI.Design methods are critical in the researches of asynchronous circuits.In this paper,we divide the history of asynchronous circuit design into 3 stages,and in particular we give a review of the last stage.We classify the methods in the last stage into 3 classes by the specification style and the granularity of circuits: the syntax-driven method,the synchronous-to-asynchronous circuits conversion method and the full-custom based design method of fine-grain asynchronous pipelines.Design methods are then surveyed and compared from several aspects.Those aspects include theory foundation,design style,design automation,and the efficiency of designed circuits.Finally,developing trends of asynchronous circuit design methods are given.",
        "keywords": [
            "synchronous-to-asynchronous circuits conversion",
            "asynchronous circuit",
            "syntax-driven",
            "fine-grain asynchronous pipeline",
            "design method"
        ],
        "authors": [
            {
                "name": "Ren Hongguang",
                "org": "School of Computer Science,National University of Defense Technology,Changsha "
            },
            {
                "name": "Shi Wei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha "
            },
            {
                "name": "Wang Zhiying",
                "org": "School of Computer Science,National University of Defense Technology,Changsha "
            },
            {
                "name": "Su Bo",
                "org": "School of Computer Science,National University of Defense Technology,Changsha "
            },
            {
                "name": "Wang Yourui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha "
            }
        ],
        "venue": "Journal of Computer-Aided Design & Computer Graphics",
        "year": 2011
    },
    "McveQ0bj": {
        "id": "McveQ0bj",
        "title": "Composite method on temperature control concrete with PCM",
        "abstract": "Temperature cracks in concrete,especially in mass concrete,lack efficient methods.A new method is proposed to control temperature cracks smartly in concrete using PCM(phase change material).Introduces characteristics of PCM in concrete and the selection principles.It proposes a simple and efficient encapsulating method to prevent the leakage of solid-liquid PCM.",
        "keywords": [
            "phase-change temperature control",
            "encapsulation method",
            "temperature crack",
            "smart"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Institute Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "HOU Jing-peng",
                "org": "School of Civil Engineering,Institute Northeast Dianli University,Jilin ,China"
            }
        ],
        "venue": "Concrete",
        "year": 2011
    },
    "sPxWb0T8": {
        "id": "sPxWb0T8",
        "title": "Design of lower computer system for wireless sensor networks monitoring on mine tunnel",
        "abstract": "Aiming at the problems caused by environmental parameters monitoring in mine with wired communication currently,in order to improve the matters of complex wiring structure,fixed monitoring stations and monitor blind spots,a design scheme of wireless sensor networks monitoring lower computer system with Zig Bee technology is proposed for coal mine tunnel multi-parameter acquisition according to environmental characteristics of the mine tunnel.Multiple sensors are used,through wireless sensor networks to realize real-time monitoring and intelligently early warning of the underground environment and production parameters.Zig Bee communication protocol and hardware modularity are used.The sensors can be flexibly added.System protection module is designed with two-level watchdog to enhance the reliability and stability of the hardware system.Simulation results show that the design's longest wireless transmission distance is 110m,the lowest transmission distance is 60m when there are obstacles,and its transmission error code rate is low.The monitoring error on parameters such as gas in the mine is small,and the system has good viability and stability.",
        "keywords": [
            "secondary protection",
            "wireless sensor networks(WSNs)",
            "lower computer",
            "parameter monitoring"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            }
        ],
        "venue": "Transducer and Microsystem Technologies",
        "year": 2011
    },
    "AogyQEPp": {
        "id": "AogyQEPp",
        "title": "Comparing of prechtl's qualitative general movements assessment and electroencephalogram of children with different motor development outcomes",
        "abstract": "【Objective】 To analyze prechtl's qualitative general movements assessment(GMs) and electroencephalogram(EEG) of children with different motor development outcomes retrospectively and investigate the GMs value in predicting of cerebral palsy.【Methods】 The GMs and EEG reports of children more than one-year-old who had been hospitalized in neonatal intensive care unit were collected.The diagnosis of cerebral palsy was made according to the international cerebral palsy diagnostic definition published in 2006.Stata 11.0 was used to analyze GMs positive predictive values,negative predictive values,specificity and sensitivity among different groups and the difference of EEG.【Results】 A total of sixty-two children were enrolled,28 of them were diagnosed as cerebral palsy,11 were motor retardation and 23 were normal.The predictive validity of GMs was as following:sensitivity 96.4%,specificity 73.9%,positive predictive value 81.8% and negative predictive value 94.4%.The rate of abnormal GMs in children of cerebral palsy was significantly higher than that in motor retardation and normal children.The rate of abnormal EEG in children of cerebral palsy and motor retardation were 78.6% and 81.8% respectively,higher than that in normal children(53.3%).The abnormalities of EEG mainly were sharp wave,sharp slow wave,high voltage and slow basic activities.【Conclusions】 GMs assessment could be used in high risk infants within 4 to 5 months to give a reliable and valid prediction for later motor development outcome,especially for cerebral palsy.Application of GMs and EEG would help comprehensive assessment of patients' function status.",
        "keywords": [
            "prechtl's qualitative general movements assessment",
            "cerebral palsy",
            "high risk infant",
            "motor development outcome",
            "electroencephalogram"
        ],
        "authors": [
            {
                "name": "GONG Chun-dan",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "PENG Yong-mei",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "MA De-jun",
                "org": " Department of Neonatology Maternal and Child Health Hospital of Cangzhou City,Cangzhou,Hebei ,China"
            },
            {
                "name": "SHI Wei",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "HOU Fang-hua",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "SU Yi",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            },
            {
                "name": "LI Yun",
                "org": " Shanghai Minhang MCH Hospital,Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": " Children's Hospital,Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Child Health Care",
        "year": 2013
    },
    "gF4rYGFh": {
        "id": "gF4rYGFh",
        "title": "Facilitating the Flexible Modeling of Human-Driven Workflow in BPEL",
        "abstract": "BPEL can automate orchestrations for cross-organizational web services; however, it meets a serious challenge from modeling human-intensive business activities. This paper distinguishes human-driven workflow from automated process, and uses State Machine to model human-driven workflow, then transforms State Machine-style workflow to BPEL process, finally integrates BPEL-style human-driven process with automated process. The goal of our work is to utilize the flexibility and efficiency of State Machine to model complex and dynamic business process, and provides a novel procedure to model human-intensive business activities to complement the limitation of BPEL. This procedure has been implemented in DartFlow – a service composition platform for the sharing of the knowledge and services.",
        "keywords": [
            "human-driven workflow",
            "human-intensive business activity",
            "flexible modeling",
            "state machine-style workflow",
            "cross-organizational web service",
            "bpel process",
            "novel procedure",
            "bpel-style human-driven process",
            "automated process",
            "state machine",
            "dynamic business process",
            "modeling",
            "computer science",
            "application software",
            "knowledge management",
            "web service",
            "bpel",
            "business process execution language",
            "protocols",
            "electronic commerce",
            "face",
            "finite state machines",
            "business process",
            "web services",
            "workflow"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Jian Wu",
                "org": ""
            },
            {
                "name": "Shaolin Zhou",
                "org": ""
            },
            {
                "name": "Ling Zhang",
                "org": ""
            },
            {
                "name": "Yuyu Yin",
                "org": ""
            },
            {
                "name": "Zhaohui Wu",
                "org": ""
            }
        ],
        "venue": "AINA Workshops",
        "year": 2008
    },
    "3Ewvksdf": {
        "id": "3Ewvksdf",
        "title": "Perovskite KNi0.8Co0.2F3 nanocrystals for supercapacitors",
        "abstract": "Perovskite KNi0.8Co0.2F3 nanocrystals were introduced as potential electrode materials for supercapacitors, which exhibited superior specific capacity and rate behavior owing to the optimal synergistic effect of Ni and Co redox species. The AC//KNi0.8Co0.2F3 asymmetric capacitor delivered high power and energy densities together with excellent cycling stability.",
        "keywords": "",
        "authors": [
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Xiuli Han",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Yong Zhou",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Weifeng Hong",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University (XTU),Xiangtan,P. R. China"
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2017
    },
    "3xdsrrVp": {
        "id": "3xdsrrVp",
        "title": "Research and Implementation of a Low Power Asynchronous Multiplier",
        "abstract": "The asynchronous logic only performs actions on demand,and it is often adopted in the power-efficient design.There are three significant factors that may affect the power consumption of pipelined circuits:the structure of the pipeline,the behavior of the operation,and characteristics of operands.In this paper,the three factors are analyzed,and a power-optimized de-synchronized multiplier considering the influence of the factors is designed.The experiments show that the proposed multiplier has lower power dissipation and higher performance than the traditional de-synchronized multipliers.",
        "keywords": [
            "low power",
            "pipeline structure optimization",
            "asynchronous",
            "multiplier",
            "operand detecting"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "SU Bo",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "REN Hong-guang",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG Zhi-ying",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            }
        ],
        "venue": "Computer Engineering & Science",
        "year": 2012
    },
    "X1ME59rW": {
        "id": "X1ME59rW",
        "title": "Renal expression of RANK-RANKL in a rat model of puromycin aminonucleoside nephropathy]",
        "abstract": "To investigate RANK-RANKL expression in the kidneys of a rat model of puromycin aminonucleoside nephropathy (PAN).Thirty-six SD rats were randomly divided into PAN model group and normal control group. PAN was induced by a single intravenous injection of 100 mg/kg puromycin aminonucleoside. Serum creatinine and 24-hour urinary protein were measured on days 3, 7, and 14 after the injection, and renal pathologies were assessed with optical and immune transmission electron microscopy. The expression of RANK and RANKL in the kidneys was examined using reverse transcription-polymerase chain reaction (RT-PCR) and Western blotting.The PAN model rats showed massive proteinuria and elevated serum creatinine on day 3, which peaked on day 7. RANK-RANKL protein and mRNA expressions in PAN model group was higher than those in the control group. In the PAN rats, RANK was expressed mainly on the top cell membrane and in the cytoplasm of renal podocytes with a significantly increased expression level compared with that in the control group.The PAN rat model shows aberrant RANK and RANKL expressions in the podocytes, indicating their contribution to podocyte injury in PAN.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhonglin Feng",
                "org": "Department of Nephrology, Guangdong Generral Hospital/Guangdong Provincial Academy of Medical Sciences, Guangzhou 510080, China. E-mail: 13828431229@139.com."
            },
            {
                "name": "Shuangxin Liu",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Houqin Xiao",
                "org": ""
            },
            {
                "name": "Xinling Liang",
                "org": ""
            },
            {
                "name": "Xiaoying Liu",
                "org": ""
            },
            {
                "name": "Zhiming Ye",
                "org": ""
            },
            {
                "name": "Suxia Wang",
                "org": ""
            },
            {
                "name": "Yongzheng Liang",
                "org": ""
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Wenjian Wang",
                "org": ""
            },
            {
                "name": "Yanhui Liu",
                "org": ""
            },
            {
                "name": "Ping Mei",
                "org": ""
            },
            {
                "name": "Lixia Xu",
                "org": ""
            },
            {
                "name": "Jianchao Ma",
                "org": ""
            },
            {
                "name": "Yunfeng Xia",
                "org": ""
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2014
    },
    "E5QoQhW0": {
        "id": "E5QoQhW0",
        "title": "The complete mitochondrial genome sequence of Abudefduf Bengalensis (Perciformes; Pomacentridae)",
        "abstract": "AbstractThe complete mitochondrial genome of marine fish Abudefduf bengalensis was sequenced by the high throughput sequencing method. The genome of this species is 16,776 bp in length, consisting of 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. The gene arrangement of A. bengalensis is identical to that of other common fishes. Phylogenetic tree based on 13 protein-coding genes shows that the clade of genus Abudefduf has a closer phylogenetic relationship to the lineage of genus Amphiprion and Premnas biaculeatus than to Labracinus cyclophthalmus.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Life Science, Foshan University, Foshan, Guangdong, China;"
            },
            {
                "name": "Wei Shi",
                "org": "College of Life Science, Foshan University, Foshan, Guangdong, China;"
            },
            {
                "name": "Hairong Luo",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, China"
            },
            {
                "name": "Hui Yu",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, China"
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "T9lBUhDX": {
        "id": "T9lBUhDX",
        "title": "Modeling and design of regional traffic dynamic guidance algorithm",
        "abstract": "In order to manifest high superiority and high efficiency of traffic guidance system, this paper analyzes the traffic guidance system by means of variable message signs, and studies dynamic regional guidance problems under the conditions of real-time traffic, and puts forward a regional traffic dynamic guidance algorithm. The algorithm balances traffic flow by partitioning traffic guidance regions dynamically and changing the turning ratio of vehicles at intersections in the guidance regions. In order to make analysis of the algorithm, this paper applies cellular automaton to simulate traffic environment on SWARM platform, and verify the effectiveness of the algorithm. The results of the simulation show that the overall average travel time of the induced dynamic modeling approach is reduced by 20% to 25% and the average waiting time is reduced by 4% to 10% compared to the use of the static regional guidance algorithm. © 2008 IEEE.",
        "keywords": [
            "real time information",
            "cellular automaton",
            "algorithms",
            "intelligent transportation systems",
            "cellular automata",
            "traffic flow"
        ],
        "authors": [
            {
                "name": "Shaolin Zhou",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhi Tang",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhaohui Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "ITSC",
        "year": 2008
    },
    "ymWiggwk": {
        "id": "ymWiggwk",
        "title": "Clinical analysis of uremic pruritus in patients maintaining hemodialysis",
        "abstract": "AIM:To investigate the prevalence,mechanism and prognostic significance of uremic pruritus (UP) in chronic hemodialysis patients. METHODS:Totally 238 adult hemodialysis patients were included in this study and followed up for 3 years. The frequency and the intensity of UP were evaluated using visual analogue scale (VAS) in all the patients. The relationship between VAS scores and stable clinical or laboratory data was analyzed by multiple linear regression analysis. The relationship between UP and patient prognosis was also tested by Kaplan-meier analysis. RESULTS:One hundred and thirty-two patients were found having UP with a frequency of 55.5%. Of them,53 cases(40.2%) had mild UP with a VAS score 1-3,59 cases(44.7%) had moderate UP with a VAS score 4-6 and 20 cases(15.1%)had severe UP with a VAS score 7-10. There were 31 patients (23.5%)with local UP and 101 patients (76.5%) with generalized UP. The analysis of multiple linear regression indicated that VAS score of UP was associated with the levels of serum iPTH,Ca×P product and hematocrit,but not with age,sex,duration of hemodialysis,blood pressure,serum urea nitrogen,creatinine,uric acid,calcium,phosphate,albumin,transferrin,Kt/V and C reactive protein (CRP). Kaplan-meier analysis also indicated that UP was not associated with the prognosis of patients. CONCLUSION:The intensity of UP in patients maintaining hemodialysis is associated with the levels of serum iPTH,Ca×P product and hematocrit,but not with age,sex,duration of hemodialysis,blood pressure,serum urea nitrogen,creatinine,uric acid,calcium,phosphate,albumin,transferrin,Kt/V and CRP. UP is not a marker for poor prognosis.",
        "keywords": [
            "pruritus",
            "uremia",
            "pathogenesis",
            "renal dialysis",
            "prognosis"
        ],
        "authors": [
            {
                "name": "XIA Yun-Feng",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIANG Xin-Ling",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-Xin",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIANG Yong-Zheng",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "TAO Yi-Ming",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "HE Chao-Sheng",
                "org": " Department of Nephrology,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Science,Guangzhou ,China"
            }
        ],
        "venue": "Journal of the Fourth Military Medical University",
        "year": 2009
    },
    "7aT2v4XU": {
        "id": "7aT2v4XU",
        "title": "Widely tunable monochromatic sources and novel detection scheme for THz imaging",
        "abstract": "",
        "keywords": [
            "conversion efficiency",
            "crystals",
            "terahertz radiation"
        ],
        "authors": [
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            },
            {
                "name": "wei shi",
                "org": "lehigh university"
            }
        ],
        "venue": "",
        "year": 2005
    },
    "x2W74t6F": {
        "id": "x2W74t6F",
        "title": "Improving metabolic stability with deuterium: The discovery of HWL-066, a potent and long-acting free fatty acid receptor 1 agonists.",
        "abstract": "The free fatty acid receptor 1 (FFA1) is a potential target due to its function in enhancing of glucose-stimulated insulin secretion. The FFA1 agonist GW9508 has great potential for the treatment of type 2 diabetes mellitus, but it has been suffering from high plasma clearance probably because the phenylpropanoic acid is vulnerable to β-oxidation. To identify orally available analog without influence on the unique pharmacological mechanism of GW9508, we tried to interdict the metabolically labile group by incorporating two deuterium atoms at the α-position of phenylpropionic acid affording compound 4 (HWL-066). As expected, HWL-066 revealed a lower clearance (CL = 0.23 L  hr  kg ), higher maximum concentration (C  = 5907.47 μg/L), and longer half-life (T  = 3.50 hr), resulting in a 2.8-fold higher exposure than GW9508. Moreover, the glucose-lowering effect of HWL-066 was far better than that of GW9508 and comparable with TAK-875. Different from glibenclamide, no side-effect of hypoglycemia was observed in mice after oral administrating HWL-066 (80 mg/kg).",
        "keywords": [
            "deuterium",
            "diabetes",
            "free fatty acid receptor",
            "pharmacokinetic profiles",
            "phenylpropanoic acid"
        ],
        "authors": [
            {
                "name": "Chunxia Liu",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Zheng Li",
                "org": "School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China."
            },
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Huilan Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Nasi Wang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Yuxuan Dai",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Chen Liao",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Wenlong Huang",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Hai Qian",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, China."
            }
        ],
        "venue": "Chemical biology & drug design",
        "year": 2018
    },
    "cthEBXXm": {
        "id": "cthEBXXm",
        "title": "Effect of Irradiation Time of Nitrogen Ion Beam on Biological Features of M_2 Winter Wheat",
        "abstract": "In order to investigate the appropriate length of time for nitrogen ion beam irradiation on winter wheat,winter wheat variety Xicheng 1 was treated by 5 min or 10 min of irradiation from N+ beams of 30 keV,4×1016 N+/cm2.Analysis was carried out on the rate of emergence,tillering,panicles per plant,FGPP,KGW and plant height of M2 winter wheat and control.Results showed that the N+ irradiation for 5 min could reduce plant height,although there were some adverse effects on biological traits.Therefore,it could be used as a method for dwarf breeding of winter wheat.",
        "keywords": [
            "length of time",
            "nitrogen ion beam",
            "biological effect",
            "winter wheat"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Chengdu Vocational College of Agricultural Science and Technology,Chengdu ,China"
            },
            {
                "name": "TANG Xue-song",
                "org": "Chengdu Vocational College of Agricultural Science and Technology,Chengdu ,China"
            }
        ],
        "venue": "Hubei Agricultural Sciences",
        "year": 2011
    },
    "7etWtEyt": {
        "id": "7etWtEyt",
        "title": "Interrelationship of CO, Weak Acids, Bases, and pH in Scale Prediction and Control",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "lu wang",
                "org": ""
            },
            {
                "name": "ross c tomson",
                "org": ""
            },
            {
                "name": "amy t kan",
                "org": ""
            },
            {
                "name": "mason b tomson",
                "org": ""
            },
            {
                "name": "chao yan",
                "org": ""
            },
            {
                "name": "syed razavi",
                "org": ""
            },
            {
                "name": "kevin wang",
                "org": ""
            },
            {
                "name": "fei yan",
                "org": ""
            },
            {
                "name": "huiguang zhu",
                "org": ""
            },
            {
                "name": "nan zhang",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "w2uFFUYA": {
        "id": "w2uFFUYA",
        "title": "Surgical management of intra-and extracranial communicating tumor",
        "abstract": "Objective To summarize the surgical management of intra-and extracranial communicating tumor.Methods A total of 35 patients with cranial communicating tumors was divided into simple type(including cranial-orbital type,cranial-nasal type,cranial-cervical type,etc.)and extensive type.The operative approach and efficiency of treatment were retrospectively analyzed.Results There was no death related to operation in this group.Tumors were removed totally in most simple type cases and the prognosis of benign ones was satisfactory.However,the operations of extensive type cases were comparatively complicated.During follow up as long as 6 years,two cases died from tumor recurrence and metastasis.Conclusion Reasonable operative approach,protection and restoration of important anatomic structures and cooperation of related departments are the important factors for improving outcomes of surgical treatment of intra-and extracranial communicating tumors.",
        "keywords": [
            "Operative approach",
            "Intra-and extracranial communicating tumors"
        ],
        "authors": [
            {
                "name": "CHEN Jian",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "NI Lanchun",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2010
    },
    "oxqkFmMF": {
        "id": "oxqkFmMF",
        "title": "The Implementation of JMF of Audio Steam Multicast System Based on RTP",
        "abstract": "This paper introduces the structure design and protocol selection of audio steam multicast system,probes into the JMF implementation of the server side,and expounds the implementing method of the client side.",
        "keywords": [
            "real time transmission protocol",
            "audio steam multicast system",
            "real time transmission control protocol"
        ],
        "authors": [
            {
                "name": "YAN Gai-zhen",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "m1n9BQAf": {
        "id": "m1n9BQAf",
        "title": "A colorimetric and near-infrared fluorescent probe for hydrogen polysulfides and its application in living cells",
        "abstract": "Abstract   The development of probes for rapid, selective, and sensitive detection of the hydrogen polysulfides is of great importance in biological science. We report here a new Near-infrared (NIR) fluorescent off-on probe for selective and sensitive detection of hydrogen polysulfides (H 2 S n ) with colorimetric and NIR fluorescent dual signal changes. The probe was synthesized by an esterification reaction coupling between a dicyanomethylene-benzopyran (DCMB) dye and a bis-electrophilic H 2 S n  capture group 2-fluoro-5-nitrobenzoic acid. The probe showed a specific off-on response to H 2 S n  in aqueous solution with nanomolar LOD, and without interference by a range of competing sulfocompounds and several reactive nitrogen and oxygen species. Moreover, it can be used for imaging of endogenous H 2 S n  in living cells.",
        "keywords": "",
        "authors": [
            {
                "name": "Kai-Bin Li",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            },
            {
                "name": "Fengzao Chen",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            },
            {
                "name": "Qiu-Hong Yin",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            },
            {
                "name": "Siqi Zhang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            },
            {
                "name": "Deman Han",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China"
            }
        ],
        "venue": "Sensors and Actuators B-chemical",
        "year": 2018
    },
    "w8NS8rH7": {
        "id": "w8NS8rH7",
        "title": "Exposure to waterborne nTiO2 reduces fertilization success and increases polyspermy in a bivalve mollusc: A threat to population recruitment.",
        "abstract": "Fertilization success is crucial for the population recruitment of an organism. However, little is known about the threat of nanoparticles to the fertilization of broadcast spawners. Therefore, the effects of nTiO2 on fertilization success, polyspermy rate, sperm velocity, gametic DNA damage, sperm-egg collision probability, gamete fusion and oocytes ultra-structure were investigated in a broadcast spawning bivalve, Tegillarca granosa. Results obtained show that fertilization success significantly decreased, whereas polyspermy risk markedly increased upon nTiO2 exposure. In addition, nTiO2 exposure led to a significant reduction in sperm swimming velocity, which would subsequently constrain gamete collisions. In addition, nTiO2 exposure resulted in a significant decline in gamete fusion per collision along with aggravated DNA damage in gametes. Furthermore, ultra-structural analysis illustrated that nTiO2 attaching to oocyte surface and subsequently resulting in microvillus disassociation and plasma membrane damage. In conclusion, the results obtained suggest a significant threat from NP pollution to the recruitment of broadcast spawning invertebrates.",
        "keywords": "",
        "authors": [
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Jiahuan Rong",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Xiaofan Guan",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Hongxiang Sun",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2019
    },
    "DYgdllE9": {
        "id": "DYgdllE9",
        "title": "Cavity Dumped Laser Using Fast GaAs Photoconductive Switch",
        "abstract": "Cavity dumping is an effective technique for generating Q-switched laser pulses of relatively large energy and extremely short time duration,and the width of Q-switched pulses is primarily a function of the oscillator cavity length.The solid state lateral semi-insulating GaAs photoconductive semiconductor switch(PCSS) has the unique ability to handle high power at very fast response time with very little timing jitter.A novel and effective technique of cavity dumping laser for generating short Q-switched laser pulses with a GaAs PCSS is presented.In a flashlamp pumped Nd∶YAG laser with 20 cm long stable resonator,1.7 ns short laser pulses have been obtained,and the pulse to pulse duration instability is less than 7% and energy instability is less than 3%.",
        "keywords": [
            "Cavity dumping",
            "Electro-optical Q-switched",
            "GaAs photoconductive switch",
            "Lasers technique",
            "Nd:YAG laser",
            "Stable resonator"
        ],
        "authors": [
            {
                "name": "Zhu Shaolan",
                "org": "1State Key Laboratory of Transient Optics and Photonics,Xi′an Institute of Optics andPrecision Mechanics,Chinese Academy of Sciences,Xi′an,Shaanxi ,China;2Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "Wei Zhao",
                "org": "Xi'an Institute of Optics and Precision Mechanics Chinese Academy of Sciences(Chinese Academy of Sciences,Xi'an Institute of Optics and Precision Mechanics),Xi'an,China"
            },
            {
                "name": "Baiyu Liu",
                "org": "Xi'an Institute of Optics and Precision Mechanics Chinese Academy of Sciences(Chinese Academy of Sciences,Xi'an Institute of Optics and Precision Mechanics),Xi'an,China"
            },
            {
                "name": "Shi Wei",
                "org": "3Department of Applied Physics,Xi′an University of Technology,Xi′an,Shaanxi ,China"
            },
            {
                "name": "Yang Yanlong",
                "org": "1State Key Laboratory of Transient Optics and Photonics,Xi′an Institute of Optics andPrecision Mechanics,Chinese Academy of Sciences,Xi′an,Shaanxi ,China;2Graduate University of Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Lasers",
        "year": 2011
    },
    "iK1uxEOo": {
        "id": "iK1uxEOo",
        "title": "A novel mitochondria-targeting fluorescent probe for hydrogen sulfide in living cells",
        "abstract": "A novel mitochondria-targeting fluorescent probe compound S-N3 for hydrogen sulfide (H2S) in living cells has been designed and synthesized in this study. This article contained the chemosynthesis and some studies on bioactivity of the target compound in living cells. Compound S-N3 is easy to synthesize and can remain stable under the effect of pH, system and photostability. In addition, it shows low cytotoxicity in cell imaging. And it can react with H2S highly selective in PBS or FBS solution, which would cause the obvious increase in fluorescence intensity. Therefore, the low-cost detection method for H2S is allowed for monitoring the quantity of H2S existed in the mitochondria.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China"
            },
            {
                "name": "Miaobo Pan",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China"
            },
            {
                "name": "Hao Qiang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China"
            },
            {
                "name": "Qianqian Qiu",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China"
            },
            {
                "name": "Wenlong Huang",
                "org": "China Pharmaceutical University Center of Drug Discovery Nanjing China"
            },
            {
                "name": "Haiyan Lin",
                "org": "Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceutical University Center of Drug Discovery Nanjing China"
            },
            {
                "name": "Liang Ge",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China"
            }
        ],
        "venue": "Chemical Biology & Drug Design",
        "year": 2017
    },
    "AyGKpCpa": {
        "id": "AyGKpCpa",
        "title": "Design, synthesis and biological evaluation of novel 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as potential BRD4 inhibitors.",
        "abstract": "Recently, diverse kinase inhibitors were reported having interaction with BRD4. It provided a strategy for developing a new structural framework for the next-generation BRD4-selective inhibitors. Starting from PLK1 kinase inhibitor BI-2536, we designed 18 compounds by modifying dihydropteridine core. Compound 23 showed potent BRD4 inhibitory activities with IC50 of 79 nM and no inhibitory activities for PLK1. Cell antiproliferation assay was performed and potent inhibitory activity against MV4; 11 with IC50 of 1.53 mu M. Cell apoptosis and western blotting indicated compound 23 induced apoptosis by down-regulating c-Myc. These novel selective BRD4 inhibitors provided new lead compounds for further drug development.",
        "keywords": [
            "BRD4 inhibitors",
            "Anti-tumor",
            "BI-2536",
            "c-Myc"
        ],
        "authors": [
            {
                "name": "Xinzhou Bi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Jieming Li",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Jiuhui Li",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Yuxuan Dai",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Qifei Li",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenjie Zhang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenlong Huang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Cheng Jiang",
                "org": "China Pharmaceut Univ, Jiangsu Key Lab Drug Design & Optimizat, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOORGANIC & MEDICINAL CHEMISTRY",
        "year": 2019
    },
    "hI2GT08g": {
        "id": "hI2GT08g",
        "title": "Neurotoxicity induced by Ceftazidime treatment in chronic renal failure patients on maintenance hemodialysis.",
        "abstract": "Objective Ceftazidime-induced neurotoxicity is often underestimated or misinterpreted by clinicians. To understand this ailment, we described 21 hemodialysis cases with ceftazidime-related neurotoxicity, and compared the effect of ceftazidime clearance by different blood purification methods. Methods We recruited the maintenance hemodi-alysis (MHD) patients complicated with psychiatric symptoms after ceftazidime treatment in Guangdong General Hospital from 1999 to 2008. Their neurotoxic symptoms induced by ceftazidime, and blood ceftazidime concentrations before and after hemodialysis were observed. Their clinical symptoms were then analyzed along with the efficiency of ceftazidime clearance by different blood purification methods. Results The involvement of central nervous system induced by ceftazidime treatment was found in 21 chronic renal failure patients on MHD. Their average age was 69.1 ± 6.4 years old, indicating the higher incidence in older patients. The frequent findings included confusion and spatial disorientation (81% patients), myoclonus (62%), and psychiatric disturbances (52%). The average Glassgow score increased, and recovery from neurotoxicity began after blood purification in all these patients. Neurotoxocity improved in less than 24 hours after blood purification. Blood ceftazidim concentrations before and after blood purification were measured in 13 cases, of which 5 cases were treated with hemodialysis, and 8 cases with on-line hemodiafiltration. The ceftazidime clearance was more efficient by hemodiafiltration than by hemodialysis, in accordance with the differences of symptom improvement by the two blood purification methods. Conclusions Ceftazidime can induce neurotoxicity in MHD patients. For elderly MHD patients, ceftazidime dose should be adjusted to avoid neurotoxicity. Awareness of thepotential nervous system complications following ceftazidime administration should be emphasized.",
        "keywords": [
            "Ceftazidime",
            "Neurotoxicity",
            "Blood purification",
            "High efficiency liquid chromatography"
        ],
        "authors": [
            {
                "name": "LIU Shuang-xin",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China;Southern Medical University, Guangzhou, Guangdong , China"
            },
            {
                "name": "SHI Wei",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "CHEN Tie-feng",
                "org": "Central Research Laboratory, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "LAO Hai-yan",
                "org": "Central Research Laboratory, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "YE Zhi-ming",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "ZHANG Bin",
                "org": ""
            },
            {
                "name": "HE Chao-sheng",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "XIA Yun-feng",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "MA Jian-chao",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "XU Li-xia",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            },
            {
                "name": "TAO Yi-ming",
                "org": ". 1Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong , China"
            }
        ],
        "venue": "Chinese Journal of Blood Purification",
        "year": 2010
    },
    "oOzb2Op9": {
        "id": "oOzb2Op9",
        "title": "Design of Protection System of Wireless Sensor Equipment for Mine Based on Embedded",
        "abstract": "In view of the existing wireless sensor equipment for mine can not work in some conditions of the mining area because of its limited anti-interference ability,in this paper we design a computer protection system composed of multi-level watchdogs.The system provides a multi-level protection measure,escalating the level of protection according to the severity of failures,when the control system hardware and software failures occur,different watchdogs start different protection measures to make the system return to normal.This design has been proved to be effective in a number of mine wireless control system transformations in practice.",
        "keywords": [
            "anti-interference",
            "multi-level protection",
            "wireless sensor",
            "embedded",
            "watchdog"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            },
            {
                "name": "LI Li-li",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,China"
            }
        ],
        "venue": "Microcomputer Information",
        "year": 2011
    },
    "4GmwfLCk": {
        "id": "4GmwfLCk",
        "title": "Association of cardiovascular events with serum fetuin A and coronary artery calcification in ESRD patients.",
        "abstract": "Objective To investigate the potential contributing effects of reduced serum fetuin A and coronary artery calcification (CAC) on cardiovascular events in end stage renal disease (ESRD) patients. Methods Thirty-eight ESRD patients on chronic hemodialysis (duration of hemodialysis less than 6 months)were enrolled in this study.Controls consisted of 22 non-ESRD patients with chronic kidney diseases (CKD). Serum fetuin A and related parameters, along with CAC score quantified by Multislice Spiral CT scan, were examined at the initiation of this study. The patients were followed up for 18 months for appraising cardiovascular events defined as cardiac failure, angina pectoris or myocardial infarction. Results During the 18 months follow-up, significant difference in cardiovascular events was documented in patients with ESRD (30 times) and without ESRD (3 times,P=0.001). Eighteen cases of CAC(62.07%)were identified by CT scan in 29 ESRD patients. Stepwise regression analysis in 38 ESRD patients without induction of CAC score indicated that fetuin A (P<0.01), LDL-C (P=0.008) and CRP (P=0.014) were independently associated with cardiovascular events. After induction of CAC score, stepwise regression analysis in 29 ESRD patients with CAC showed that fetuin A (P < 0.0005) and CAC score (P=0.006) were associated with cardiovascular events. Serum fetuin A was lower in patients with CAC than that in patients without CAC (P=0.001). Stepwise regression analysis showed that CAC was associated with reduce fetuin A (P< 0.0005) and elevated serum phosphorus (P=0.001). Conclusion Reduced serum fetuin A and coronary artery calcification may contribute to cardiovascular events in ESRD patients receiving hemodialysis.",
        "keywords": [
            "Renal dialysis",
            "Calcification",
            "Coronary vessels",
            "Kidney failure",
            "chronic",
            "Cardiovascular diseases",
            "α-Fetoproteins"
        ],
        "authors": [
            {
                "name": "LIANG Xin-ling",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "SHI Wei",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "ZHANG Bin",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "LIN Qiu-xiong",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "HUANG Mei-ping",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "WANG Wen-jian",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "YE Zhi-ming",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            },
            {
                "name": "HE Chao-sheng",
                "org": ".Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou , China"
            }
        ],
        "venue": "Chinese Journal of Nephrology",
        "year": 2006
    },
    "D95yJRmN": {
        "id": "D95yJRmN",
        "title": "Non-concerted evolution in ribosomal ITS2 sequence in Cynoglossus zanzibarensis (Pleuronectiformes: Cynoglossidae)",
        "abstract": "Abstract   The nuclear ribosomal RNA genes (nrDNA) include three rRNA genes (18S, 5.8S, and 28S) and two internal transcribed spacers (ITS1 and ITS2). The lack of variability in nrDNA has been explained as the result of concerted evolution. In fact, many examples of variation have been discovered, suggesting a non-concerted evolution process. There are few studies on ITS2 in teleostean fishes; particularly no reports on flatfishes. In this study, we focused on ITS2 in Zanzibar tonguesole,  Cynoglossus zanzibarensis  (Pleuronectiformes: Cynoglossidae). Three types of ITS2 sequences (Type A, B, and C) coexisted and mainly differ in length, nucleotide diversity (π), secondary structure, and minimum free energy. Based on these different features, Type B and C were speculated as the putative pseudogenic ITS2 region. Moreover, Type C sequences were detected as recombinant from crossing over between Type A and B sequences. To our knowledge, this is the first report on ITS2 recombination in animal ribosomal RNA genes. The high degree of ITS2 sequence polymorphism at the intraindividual level supported a non-concerted evolution pattern in the  C. zanzibarensis  genome. These results provide useful data for further studies on ITS2 in flatfishes and contribute to polymorphism analyses of ribosomal RNA genes in teleostean fishes.",
        "keywords": "",
        "authors": [
            {
                "name": "Li Gong",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510000, China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510000, China"
            },
            {
                "name": "Min Yang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510000, China"
            },
            {
                "name": "Lizhen Si",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510000, China"
            },
            {
                "name": "Xiao-Yu Kong",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510000, China"
            }
        ],
        "venue": "Biochemical Systematics and Ecology",
        "year": 2016
    },
    "cO6qL6W6": {
        "id": "cO6qL6W6",
        "title": "A Review on Terrorism from the Perspective of Terrorists",
        "abstract": "There is still no consensus about the definition of terrorism.In this article,terrorism refers to the acts of any individual,group or organization in order to achieve certain political,religious or social purposes,illegally using violence or other coercive means against innocent people with the intention of catching the attention of the target objects or the public and creating an atmosphere of terror.The formation and development of terrorism can be explained by Syndrome Model,Narcissism-Aggression Model,Frustration-Aggression Model,Tool Model,Social Context Model and other integrated models.The authors reviewed these models and proposed several psychological strategies for terrorism prevention.In psychology,the empirical research on terrorism is relatively small,and mostly focuses on the description and interpretation.So the research on the prediction and application of terrorism need to be further developed.",
        "keywords": [
            "terrorism",
            "violence",
            "terror",
            "counterterrorism",
            "terrorist"
        ],
        "authors": [
            {
                "name": "JIA Feng-Xiang",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2010
    },
    "kmcmi76r": {
        "id": "kmcmi76r",
        "title": "miR-202 expression concentration and its clinical significance in the serum of multiple myeloma patients.",
        "abstract": "Objectives: To explore microRNA-202 (miR-202) expression in serum of patients with multiple myeloma (MM), and investigate correlations between serum miR-202 expression and the development and prognosis of MM. Design and methods: RNA was extracted from serum by QIAGEN miRNeasy Mini kit. Reverse transcription was performed with specific stem-loop primers. SYBR Green I QF-PCR was applied to detect the relative expression of miR-202 in 40 MM patients and 30 healthy controls. The linearity, specificity and reproducibility were evaluated. In addition, correlations between the relative expression of serum miR-202 and the concentrations of lactic acid dehydrogenase (LDH), beta M-2, lambda light chain and kappa light chain were assessed. Results: The relative expression of miR-202 in MM patients 1.503 (0.161-9.831) was significantly higher than that in healthy controls 1.000 (0.105-3.046) (P < 0.01) and was significantly correlated with serum beta M-2 and kappa light chain concentrations (r = 0.366, P = 0.0305; r = 0.358, P = 0.0348). Conclusions: The relative expression of serum miR-202 in MM patients was significantly higher than that in healthy controls, and therefore it may prove to be useful in the auxiliary diagnosis of MM.",
        "keywords": [
            "SYBR Green I fluorescent quantitative PCR",
            "microRNA-202",
            "multiple myeloma"
        ],
        "authors": [
            {
                "name": "Jiajia Yu",
                "org": "Nantong Univ, Lab Med Ctr, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            },
            {
                "name": "Xiaojun Qiu",
                "org": "Nantong Univ, Dept Radiat Oncol, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            },
            {
                "name": "Xianjuan Shen",
                "org": "Nantong Univ, Surg Comprehens Lab, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Nantong Univ, Surg Comprehens Lab, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            },
            {
                "name": "Xinhua Wu",
                "org": "Nantong Univ, Surg Comprehens Lab, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            },
            {
                "name": "Guohao Gu",
                "org": "Soochow Univ, Hosp Affiliated 1, Suzhou, Jiangsu, Peoples R China"
            },
            {
                "name": "Baoli Zhu",
                "org": "Jiangsu Prov Ctr Dis Control & Prevent, Nanjing, Jiangsu, Peoples R China"
            },
            {
                "name": "Shaoqing Ju",
                "org": "Nantong Univ, Lab Med Ctr, Affiliated Hosp, Nantong, Jiangsu, Peoples R China"
            }
        ],
        "venue": "ANNALS OF CLINICAL BIOCHEMISTRY",
        "year": 2014
    },
    "EPU4RVJv": {
        "id": "EPU4RVJv",
        "title": "Association between hepatitis C virus infection and coronary artery disease in maintenance hemodialysis patients",
        "abstract": "Objective To investigate the association between hepatitis C virus (HCV) infection and coronary artery disease (CAD) in maintenance hemodialysis (MHD) patients. Methods A cross-sectional survey in MHD patients according to the infection control screening data was conducted in Guangdong General Hospital in July 2011. Patients were divided into two groups (HCV positive group, and HCV negative group). The prevalence of CAD was compared between the two groups, and logistic regression analysis was used to determined the independent risk factors. Results Among 377 MHD patients, HCV positive patients accounted for 9.0% patients, and the prevalence of CAD was 23.9%. The prevalence of CAD was 41.2% in HCV positive group, whereas 22.8% in HCV negative group (P=0.013). Logistic regression analysis showed that age, hemoglobin and low density lipoprotein were associated with increased risk of CAD, indicating that HCV infection was not an independent risk factor for CAD. Conclusion Our study did not demonstrate HCV infection as a risk factor for CAD. Whether HCV infection predicts CAD needs more prospective evidences.",
        "keywords": [
            "Coronary artery disease",
            "Hepatitis C virus infection",
            "Maintenance hemodialysis"
        ],
        "authors": [
            {
                "name": "XIE Jian-teng",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "LI Zhi-lian",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "WANG Wen-jian",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "LI Rui-zhao",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "LIANG Hua-ban",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "DONG Wei",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            },
            {
                "name": "SHI Wei",
                "org": ". Nephrology Department, Guangdong General Hospital, Guangzhou,  China"
            }
        ],
        "venue": "Chinese Journal of Blood Purification",
        "year": 2012
    },
    "2YM6nn83": {
        "id": "2YM6nn83",
        "title": "Research on the Application of NaS Battery Energy Storage System",
        "abstract": "The structure,the working principle and the parameter characteristics of sodium sulfur(NaS) battery are introduced in this paper.Then the application type and status of NaS battery are analyzed.The statistics analysis on the application of load leveling,uninterrupted power supply and emergency power supply are analyzed.Its cost composition and economic benefits are shown by taking the first megawatt-class Energy Storage System(ESS) in USA as an example.In addition,the design scheme and key technical analysis of a typical NaS battery ESS are proposed.The power conversion system,the battery management system and the monitoring system are introduced in detail.In the end,domestic demand of electrical energy storage and the application foreground of NaS battery after industrialization are presented based on the expectation of the State Grid for new energy in 2010.",
        "keywords": [
            "NaS battery",
            "application status",
            "energy storage system"
        ],
        "authors": [
            {
                "name": "Sun Bingxiang",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Jiang Jiuchun",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Shi Wei",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Zhang Weige",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Modern Electric Power",
        "year": 2010
    },
    "AgB2lWcz": {
        "id": "AgB2lWcz",
        "title": "Modern Time and Space and Female Problems",
        "abstract": "Modern time and space as a whole is the cause of female problems.Western Marxist feminists have thorough discussion on the issues and they believe that females are marginalized,objectified and repulsed by social structure and power relation due to the level feature,subjectivity,structural characteristic and power attribute of modern time and space.On the basis of new understanding of modernity,recreating understanding of modern time and space is an important path to the solution of the question.",
        "keywords": [
            "Female Problems",
            "Modern Time and Space",
            "Western Marxist Feminists"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "College of Politics and Laws,Northeast Normal University,Changchun ,China"
            },
            {
                "name": "FENG Ye",
                "org": "College of Politics and Laws,Northeast Normal University,Changchun ,China"
            }
        ],
        "venue": "Journal of Northeast Normal University(Philosophy and Social Sciences)",
        "year": 2013
    },
    "G6RgkLCh": {
        "id": "G6RgkLCh",
        "title": "Relation ship between QT_(LC) interval and heart risk factors in coronary heart disease patients",
        "abstract": "Objective To evaluate the relation ship between value of QTLC interval and heart risk factors in coronary heart disease patients.Methods The association of QTLC interval and heart risk factors and mortality in 39~75 years coronary heart disease patients of 300 men and 200 women was evaluated.Results Nomogram corrected QT interval(QTLC)prolongation and shortened was associated with elevated blood pressure and signs of cardiovascular disease with smoking.QTLC 5%~10% prolongation total cardiovascular sudden death mortality for 0.60%,over 10% prolongation of sudden death mortality for 1.00%;QTLC 5%~10% shortened of sudden death for 0.60%,over 10% shortened sudden death 1.40%.5%~10% shortened QTLCpredicted cardiovascular sudden death in men and women with disease who smoked,mortality for 1.00%,over 10% shortened sudden death mortality for 1.20%;5%~10% prolongation QTLCsudden death mortality for 0.60%,over 10% sudden death mortality for 1.00%.Implanting cardioverter-defibrillator(ICD) cure three patients prolongation QT interval and three short QT interval in one year during observation without malignant ventricular arrhythmia and mortality happen.Conclusion For coronary heart disease patients,prolonged and shortened QTLC interval predicts heart mortality and signs of cardiovascular disease.Signs of shortened and prolonged QTLC interval predicts death with heart disease who smoke.Implanting cardioverter-defibrillator could effectively decrease the incidence rate and mortality rate of malignant ventricular arrhythmia.",
        "keywords": [
            "coronary heart disease",
            "heart",
            "QTLC interval",
            "risk factors"
        ],
        "authors": [
            {
                "name": "LI Xiao-hua",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "HUANG Zuo-gui",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "DU Guo-wei",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "YU Hua",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "YIN Bo",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "LI Qian",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "JIN Hai-yan",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "XIANG Juan",
                "org": "Department of Function,Chongqing Three Gorges Central Hospital,Chongqing ,China"
            }
        ],
        "venue": "Journal of Jiangsu Practical Electrocardiology",
        "year": 2012
    },
    "1QnrQcUU": {
        "id": "1QnrQcUU",
        "title": "Synthesis and Performance of New Type Thiophene Copolymers of Side Chain Including Imine",
        "abstract": "A new thiophene monomer of side chain including imine 2,5-dibromo-3-(fluorene-2-amine) methyl thiophenes was synthesized by Schiff-base reaction using Pd(PPh3)2Cl2 and CuI as catalyst.Four new conjugate copolymers Th-PE-6,Th-PE-8,Th-PE-10,Th-PE-12 were prepared by Sonogashira coupling reaction,which were characterized by FT-IR,1H-NMR,UV-Vis,cyclic voltammogram(CV) and gel permeation chromatography(GPC).Results showed that the copolymer Th-PE-8,Th-PE-10,Th-PE-12 which emitted yellow-green light in THF solution had maximum PL emission at 467、 473、 470 nm,respectively.Th-PE-6,Th-PE-8 showed good electrochemical performance with three redox peaks from-0.2 to 0.8 V.",
        "keywords": [
            "fluorene",
            "3-thiophene formaldehyde",
            "Pd(Ⅱ) compound catalytic method",
            "alternating copolymer",
            "Schiff-base reaction"
        ],
        "authors": [
            {
                "name": "LI Xiao-dong",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "MENG Xin-tao",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "ZHANG Jian-ping",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Polymers",
        "year": 2013
    },
    "SQpqLQe8": {
        "id": "SQpqLQe8",
        "title": "Simple reflection technique for measuring the linear electro-optic coefficient of the polymer thin films",
        "abstract": "The simple reflection technique is usually used to measure the linear electro-optic (EO) coefficient (Pockels coefficient) in the development of EO polymer thin films. But there are some problems in some articles in the determination of the phase shift between the s and p light modes of a laser beam waveguided into the polymer film while a modulating voltage is applied across the electrodes, and different expressions for the linear EO coefficient measured have been given in these articles. In our research, more accurate expression of the linear EO coefficient was deduced by suitable considering the phase shift between the s and p light modes. The linear EO coefficients of several polymer thin films were measured by reflection technique, and the results of the linear EO coefficient calculated by different expressions were compared. The limit of the simple reflection technique for measuring the linear EO coefficient of the polymer thin films was discussed.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Fanqing Meng",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Dong Xü",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Gangjin Chen",
                "org": "Tongji University(Tongji University,Tongji Univ.),Shanghai,China"
            },
            {
                "name": "JinZhong Yu",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2000
    },
    "SY4UWYA2": {
        "id": "SY4UWYA2",
        "title": "A DNA-stabilized silver nanoclusters/graphene oxide-based platform for the sensitive detection of DNA through hybridization chain reaction.",
        "abstract": "A silver nanoclusters (AgNCs)/graphene oxide (GO)-based fluorescence sensor was developed for label-free DNA detection through hybridization chain reaction (HCR). A DNA sequence associated with the human immunodeficiency virus (HIV) was selected as a model target. Two DNA probes, hairpin probe 1 (H-1) and hairpin probe 2 (H-2), were partially complementary. GO was used as an adsorption material to capture the hairpin probes and a selective fluorescence quencher was used to reduce the background signal. Upon addition of AgNO3 and NaBH4, the AgNCs were synthesized at the terminals of the H-1 and H-2 probes. In the absence of target DNA (Tmv), hybridization chain reaction (HCR) could not be triggered due to the stability of H1 and H2 probes. The hairpin probe-protected AgNCs attached to the GO surface, efficiently quenching fluorescence of the AgNCs. Therefore, the system showed very low background. In presence of Taro, the target triggered the chain like assembly of H-1 and H-2 through HCR, generating a long chain of H-1 and H-2 complexes. The HCR product (AgNCs nanowires) could not be adsorbed on the surface of GO; hence, it generated a strong fluorescent signal based on the concentration of the target. Under the optimized conditions, the detection limit of the fluorescence sensor was 1.18 nM, and hence it can be applied to clinical samples.",
        "keywords": [
            "Fluorescence sensor",
            "Hybridization chain reaction",
            "Silver nanoclusters",
            "DNA detection",
            "Graphene oxide"
        ],
        "authors": [
            {
                "name": "Siqi Zhang",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Kun Wang",
                "org": "Northeastern Univ, Coll Sci, Shenyang 110819, Peoples R China"
            },
            {
                "name": "Kai-Bin Li",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Wen-Ping Jia",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Xiaoying Chen",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Ting Sun",
                "org": "Northeastern Univ, Coll Sci, Shenyang 110819, Peoples R China"
            },
            {
                "name": "De-Man Han",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            }
        ],
        "venue": "BIOSENSORS & BIOELECTRONICS",
        "year": 2017
    },
    "wB7YPjAq": {
        "id": "wB7YPjAq",
        "title": "Solubility Measurements and Predictions of Gypsum, Anhydrite, and Calcite Over Wide Ranges of Temperature, Pressure, and Ionic Strength with Mixed Electrolytes",
        "abstract": "Today’s oil and gas production from deep reservoirs permits exploitation of more oil and gas reserves but increases risks due to conditions of high temperature and high pressure. Predicting mineral solubility under such extreme conditions is critical for mitigating scaling risks, a common and costly problem. Solubility predictions use solubility products and activity coefficients, commonly from Pitzer theory virial coefficients. However, inaccurate activity coefficients and solubility data have limited accurate mineral solubility predictions and applications of the Pitzer theory. This study measured gypsum solubility under its stable phase conditions up to 1400 bar; it also confirmed the anhydrite solubility reported in the literature. Using a novel method, the virial coefficients for Ca2+ and ({text{SO}}_{4}^{2 - }) (i.e., (beta_{{{text{CaSO}}_{4} }}^{(0)} ,beta_{{{text{CaSO}}_{4} }}^{(2)} ,C_{{{text{CaSO}}_{4} }}^{phi })) were calculated over wide ranges of temperature and pressure (0–250 °C and 1–1400 bar). The determination of this set of virial coefficients widely extends the applicable temperature and pressure ranges of the Pitzer theory in Ca2+ and SO 4 2− systems. These coefficients can be applied to improve the prediction of calcite solubility in the presence of high concentrations of Ca2+ and SO 4 2− ions. These new virial coefficients can also be used to predict the solubilities of gypsum and anhydrite accurately. Moreover, based on the derived (beta_{{{text{CaSO}}_{4} }}^{(2)}) values in this study, the association constants of ({text{CaSO}}_{4}^{left( 0 right)}) at 1 bar and 25 °C can be estimated by (K_{text{assoc}} = - 2beta_{{{text{CaSO}}_{4} }}^{(2)}). These values match very well with those reported in the literature based on other methods.",
        "keywords": [
            "Pitzer theory",
            " Thermodynamics",
            " Ion pair",
            " Complexes",
            " High temperature",
            " High pressure"
        ],
        "authors": [
            {
                "name": "Zhaoyi Dai",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Amy T. Kan",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Nan Zhang",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Fangfu Zhang",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Fei Yan",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Narayan Bhandari",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Zhang Zhang",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Ya Liu",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Gedeng Ruan",
                "org": "Department of Civil and Environmental Engineering, Rice University, Houston, USA"
            },
            {
                "name": "Mason B. Tomson",
                "org": "Department of Civil and Environmental Engineering,Rice University,Houston,USA"
            }
        ],
        "venue": "Rock Mechanics and Rock Engineering",
        "year": 2017
    },
    "aefG5FqV": {
        "id": "aefG5FqV",
        "title": "Investigation of aging characteristics in explosive using terahertz time-domain spectroscopy",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            },
            {
                "name": "Chengang Dong",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            },
            {
                "name": "Lei Hou",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            },
            {
                "name": "Zhiyang Xing",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            },
            {
                "name": "Qian Sun",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            },
            {
                "name": "Lihao Zhang",
                "org": "Department of Applied Physics, Xi’an University of Technology, Xi’an 710048, P. R. China"
            }
        ],
        "venue": "International Journal of Modern Physics B",
        "year": 2019
    },
    "NaCtQdWi": {
        "id": "NaCtQdWi",
        "title": "Investigation on Therapeutic Mechanism of Jiaweifuzilizhong Extract Granule in Acute Aristolochic Acid Nephropathy",
        "abstract": "Objective To investigate the therapeutic mechanism of Jiaweifuzilizhong extract granule in acute aristolochic acid nephropathy(AAN). Methods 90 SD rats were divided into 5 groups randomly: normal control group(n=10),model group(n=20),TCM Jiaweifuzilizhong group(n=20),prednisone group(n=20),and TCM plus prednisone group(n=20).Experimental model of AAN was established in SD rats by gavage with aristolochia acid(100mg/kg·d) for three days.6 days after the experiment beginning,rats in TCM Jiaweifuzilizhong group were gavaged with extract granule(10 ml/kg·d),prednisone(0.5 mg/kg·d) was given to prednisone group,extract granule(10 ml/kgod) and prednisone(0.5 mg/kgod) were both given to TCM plus prednisone group.Three weeks later,the SOD,MDA,Bcl-2 mRNA,bax mRNA,Cytochrome C and the apoptosis of renal tubular epithelial cells were detected. Results In the renal tissue of experimental model,SOD activity and bcl-zmRNA expression were significantly decreased,and MDA level bax mRNA expression and cytochrome C level were significantly increased.In addition,a large number of apoptotic tubular epithelial cells were seen(P<0.01).In TCM group,prednisone group and the TCM + prednisone group,SOD,bcl-2mRNA were increased,MDA,bax mRNA and the release of cytochrome C were decreased and the apoptosis of the renal tubular epithelial cell were reduced(P<0.05 or P<0.01).Descending order of intensity as TCM + prednisone,prednisolone,TCM Jiaweifuzilizhong extract granule(P<0.05 or P<0.01). Conclusion The apoptosis of renal tubular epithelial involves in the pathogenesis of acute aristolochic acid nephropathy,Jiaweifuzilizhong extract granule by inhibiting the mitochondrial pathway of apoptosis in renal tubular epithelial cells,but combined with prednisone will have better effect.",
        "keywords": [
            "Jiawei Fuzi Lizhong Decoction",
            "Apoptosis",
            "Extract granule",
            "Acute aristolochic acid nephropathy"
        ],
        "authors": [
            {
                "name": "CHEN Yan-qiang",
                "org": "The First Affiliated Hospital of Guangxi Traditional Chinese Medical University,Nanning ,China"
            },
            {
                "name": "SHI Wei",
                "org": "The First Affiliated Hospital of Guangxi Traditional Chinese Medical University,Nanning ,China"
            },
            {
                "name": "HUANG Ren-fa",
                "org": "Ruikang Hospital of Guangxi Traditional Chinese Medical University,Nanning,,China"
            }
        ],
        "venue": "Lishizhen Medicine and Materia Medica Research",
        "year": 2012
    },
    "AWVtZz9P": {
        "id": "AWVtZz9P",
        "title": "Li-ion battery modeling and on-line model parameters identification for PEV",
        "abstract": "Polarization voltage is an importance parameter for battery status estimation,whereas,it can't be measured directly.The,resistance-capacitor model is adopted for polarization voltage modeling,a close connection between the order of polarization voltage model and polarization depth is then pointed out,and a fast polarization voltage identification method is proposed in this paper.The calculation method for battery depolarization time and capacity is presented in the condition of changing current discharge.The method's validity and feasibility for new and aged batteries of different manufactories are verified by FUDS simulations.The results provide data support for the estimation of battery status.",
        "keywords": [
            "mathematics modeling",
            "least-square-method fitting",
            "Li-ion battery",
            "model parameters identification",
            "depolarization"
        ],
        "authors": [
            {
                "name": "JIANG Jiu-chun",
                "org": "School of Electrical Engineering of Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "WEN Feng",
                "org": "School of Electrical Engineering of Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "WEN Jia-peng",
                "org": "School of Electrical Engineering of Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "GUO Hong-yu",
                "org": "School of Electrical Engineering of Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering of Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Journal of Electric Power Science and Technology",
        "year": 2010
    },
    "7tmSdQ9Q": {
        "id": "7tmSdQ9Q",
        "title": "Diagnostic value of miniprobe endoscopic ui trasonography for cystic lesions in upper gastrointestinal tract",
        "abstract": "Objective To evaluate the diagnostic value of the miniprobe endoscopic ultrasonography(mEUS)for cystic lesions in upper gastrointestinal trace.Methods 191 patients with protruding lesions revealed by routine gastroscopy underwent mEUS.34 of them received Endo-dop examination,in which position and depth of the probe was adjusted once signals of blood flow was detected.The image of Endo-dop was recorded.Results 191 cystic lesions comprised of 139 cyst,51 angioma and 1 lymphangiectasis.Endo-dop examination was performed on 34 patients,among which blood flow signal was detected in 26 patients with angioma,but not in the 8 with cyst.Fine needle aspiration was performedon 9 cystic lesions that showed disappearance of protrusion after retrieval of light yellow cystic fluid.1 lymphangiectasis was biopsied by means of EMR and then pathologically confirmed.Conclusion mEUS is an ideal diagnostic modality for none-echo mass in upper gastrointestinal tract.But it is difficult in distinguishing cyst from angioma according to ultraphonic image.It is valuable for Endo-dop in distinguishing cyst from angioma.",
        "keywords": [
            "cystic lesions in upper gastrointestinal tract",
            "Endo-dop",
            "Endoscopic ultrasonography"
        ],
        "authors": [
            {
                "name": "CHAO Qi-chang",
                "org": ",et al.The Third People′s Hospital of Chengdu,Chengdu,Sichuan ,China"
            },
            {
                "name": "SUN Xiao-bin",
                "org": ",et al.The Third People′s Hospital of Chengdu,Chengdu,Sichuan ,China"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.The Third People′s Hospital of Chengdu,Chengdu,Sichuan ,China"
            }
        ],
        "venue": "Sichuan Medical Journal",
        "year": 2011
    },
    "Shn9msh0": {
        "id": "Shn9msh0",
        "title": "A comparative study of the clinicopathological features in patients with IgA nephropathy with elevated uric acid level]",
        "abstract": "To explore the changes in the clinicopathological features of patients with IgA nephropathy with elevated uric acid level.A total of 171 patients with IgA nephropathy diagnosed at biopsy were classified into 3 groups, namely normotensive group with normal level uric acid (group 1), normotensive group with elevated uric acid level (group 2), and hypertensive group with elevated uric acid level (group 3). The clinicopathological features were compared between the 3 groups.From group 1 to group 3, the disease duration became elongated, body weight increased, systolic and diastolic pressures elevated, blood urea nitrogen and serum creatinine increased, glomerular filtration rate decreased, and 24-h urine protein increased; the apolipoprotein A, high-density lipoprotein and albumin levels decreased, while apolipoprotein B100, triglyceride, cholesterol and low-density lipoprotein increased. The glomerular damage, tubulointerstitial lesions and arteriole hypertrophy worsened, and Lee's grade III changes were predominant in group 1, grade III or IV in group 2 and grades III-V in group 3. Mesangial proliferative glomerulonephritis was the major pathological type in groups 1 and 2, as compared with focal segmental glomerulonephritis or sclerosing glomerulonephritis in group 3.Patients with IgA nephropathy and elevated uric acid level have greater clinicopathological damage than those with normal uric acid level, and hypertension further aggravates such damages.",
        "keywords": [
            "iga",
            "hypertension",
            "glomerulonephritis",
            "uric acid"
        ],
        "authors": [
            {
                "name": "Shen-heng Li",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China;Department of Nephropathy, Zhujiang Hospital, South Medical University, Guangzhou , China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Yun-feng Xia",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Xin-ling Liang",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Wen-jian Wang",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Jian-chao Ma",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Dan Wu",
                "org": "Department of Nephropathy, Zhujiang Hospital, South Medical University, Guangzhou , China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2010
    },
    "qR2NXBsY": {
        "id": "qR2NXBsY",
        "title": "Dynamic modeling and analysis of a wind turbine drivetrain using the torsional dynamic model",
        "abstract": "mathematical model for a horizontal axial wind turbine drivetrain was developed using the torsional multibody dynamic model. The drivetrain in this study consisted of a low-speed planetary gear stage (three identical planets with spur teeth, sun and fixed ring gears) and two high-speed spur gear stages. This typical arrangement has been commonly used in the wind turbine industry. The governing equation of the drivetrain was derived by using the Lagrange’s equation, which takes into account the kinetic and potential energies and the work from the input torque. The governing equation was solved numerically by direct numerical integration. Dynamic analysis was carried out to investigate the transient response of the drivetrain system.",
        "keywords": [
            "Wind turbine",
            " Multibody dynamics",
            " Drivetrain",
            " Mathematical model",
            " Torsional vibration",
            " Dynamic loads"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": "pohang university of science and technology"
            },
            {
                "name": "changwan kim",
                "org": "konkuk university"
            },
            {
                "name": "chinwha chung",
                "org": "pohang university of science and technology"
            },
            {
                "name": "hyunchul park",
                "org": "pohang university of science and technology"
            }
        ],
        "venue": "International Journal of Precision Engineering and Manufacturing",
        "year": 2012
    },
    "uttPEW6e": {
        "id": "uttPEW6e",
        "title": "Synthesis and Characterization of Difuran-Benzothiadiazole-Containing Poly (aryleneethynylene)Derivatives",
        "abstract": "A novel class of poly(aryleneethyny1ene) derivatives were synthesized via cross coupling(between) the large band-gap monomer,1,4-diethynyl-2,5-bis(n-dodecyloxy)benzene(PE),and low band-gap monomer,4,7-bis(5-bromo-2-furan)-2,1,3-benzothiadiazole(FBT),in the medium of tetrahydrofuran and diisopropylamine with Pd(PPh_3)_4 and CuI as catallysts.These polymers are soluble in common organic(solvents) and possess good film-formability due to the decoration of flexible alkyloxy chains.The UV-Vis(absorption,) photoluminescent and electrochemical properties of the resulted copolymers are studied.(Absorption) onsets and emission maxima of these polymers are significantly red-shifted along with the(increase) of FBT's fraction in polymers' backbones.When the maximum emissions of copolymers' films peak are located at 600—650 nm,the energy could efficiently transfer from PE units to FBT moieties in these polymers.",
        "keywords": [
            "furan",
            "benzothiadiazole",
            "poly(aryleneethynylene)"
        ],
        "authors": [
            {
                "name": "QIN Hong-mei",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Polymers",
        "year": 2010
    },
    "Kr5oK81P": {
        "id": "Kr5oK81P",
        "title": "Guest–host polyetherketone polymer for applications in integrated-optical devices: characterization",
        "abstract": "",
        "keywords": [
            "second harmonic",
            "thin film",
            "harmonic generation",
            "optical waveguide",
            "polymers",
            "organic materials",
            "thin films"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Yujie J. Ding",
                "org": ""
            },
            {
                "name": "Xiaodong Mu",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            },
            {
                "name": "Qiwei Pan",
                "org": ""
            },
            {
                "name": "Qingtian Gu",
                "org": ""
            }
        ],
        "venue": "Journal of The Optical Society of America B-optical Physics",
        "year": 2002
    },
    "yjcFdMnh": {
        "id": "yjcFdMnh",
        "title": "Characteristics of the Circulating Current on 800 kV Insolated Phase Bus Enclosure",
        "abstract": "The transmission capacity of power system is affected by the circulating current of bus enclosure which can also induce the heat generated by loss,and accelerate the insulation aging.In this paper,the model of circulating current with the three-phase sub-aspect bus in GIS is established,and the parameters of the model are determined.The effect factors of circulating current in successive type enclosure of that are analyzed.The characteristics of circulating current in the presence of failure are studied simultaneously.The results show that the high voltage and low current should be adopted when transmitting the same capacity.The short phase distance,high erecting height,large bus radius,more earthing point,and large inductive reactance connector should be adopted,considering the geographical environment and manufacturing cost.The enclosure of GIS should be grounded in whole line,when the internal fault is calculated.",
        "keywords": [
            "circulating current",
            "gas-insulated switchgear(GIS)",
            "induced voltage",
            "metal enclosure",
            "electromagnetic transient"
        ],
        "authors": [
            {
                "name": "ZHANG Ya-ting",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "GAO Bo",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "JIA Lei",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "LI Wen-yi",
                "org": "Henan Pinggao Electiric Co.,Ltd.,Pingdingshan ,China"
            }
        ],
        "venue": "Insulators and Surge Arresters",
        "year": 2008
    },
    "ETVEcba3": {
        "id": "ETVEcba3",
        "title": "Effect of early postoperative use of ACEI/ARB or diuretics on the incidence of acute kidney injury after cardiac surgery in elderly patients]",
        "abstract": "To explore the influence of early postoperative use of angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARB) or diuretics on acute kidney injury (AKI) after cardiac surgery in elderly patients.Data from elderly patients (age≥60 years old) who underwent cardiac surgery with extracorporeal circulation in Guangdong General Hospital between January 2007 and December 2010 were analyzed in this retrospective research. The primary endpoint was AKI as diagnosed according to the serum creatinine criteria of RIFLE (risk, injury, failure, loss, end stage renal disease). The baseline serum creatinine was defined as the latest serum creatinine level before cardiac surgery. Multivariate analysis by logistic regression was used to obtain the independent risk factors for AKI.Among 618 elderly patients, 76 (12.3%) patients received ACEI/ARB during early postoperative period, 491 (79.4%) patients were given diuretics during early postoperative period, and postoperative AKI occurred in 394 (63.8%) patients. The incidence of AKI was 46.1% in patients who received early postoperative ACEI/ARB, and 66.2% in patients who did not (P<0.001). Patients who received diuretics postoperatively were less likely to suffer from AKI compared with patients who did not (57.0% vs. 89.8%, P<0.001). After adjustment of other potential factors of postoperative AKI, logistic regression analysis showed that early postoperative use of ACEI/ARB [odds ratio (OR)=0.131, 95% confidence interval (95%CI) 0.033-0.517, P=0.004], and early postoperative use of diuretics (OR=0.149, 95%CI 0.076-0.291, P<0.001) independently predicted the occurrence of AKI.Early postoperative use of ACEI/ARB or diuretics is associated with a lower incidence of AKI after cardiac surgery with extracorporeal circulation in elderly patients.",
        "keywords": [
            "angiotensin converting enzyme inhibitors",
            "angiotensin receptor blockers",
            "cardiac surgery",
            "acute kidney injury",
            "diuretics"
        ],
        "authors": [
            {
                "name": "Peng-hua Hu",
                "org": "Division of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong, China."
            },
            {
                "name": "Yuan-han Chen",
                "org": ""
            },
            {
                "name": "Xin-ling Liang",
                "org": ""
            },
            {
                "name": "Rui-zhao Li",
                "org": ""
            },
            {
                "name": "Zhi-lian Li",
                "org": ""
            },
            {
                "name": "Fen Jiang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Zhonghua wei zhong bing ji jiu yi xue",
        "year": 2013
    },
    "cWhAVFiN": {
        "id": "cWhAVFiN",
        "title": "QUATERNARY MAGNETOSTRATIGRAPHY OF THE GONGHE BASIN ON THE NORTHEASTERN OF THE QINGHAI-TIBETAN PLATEAU",
        "abstract": "Study of the Quaternary magnetostratigraphy in the Gonghe basin on the northeastern margin of the Qinghai-Tibetan Plateau shows that four normal paleomagnetic polarity intervals and three reverse paleomagnetic polarity intervals are recorded in the Quaternary section and that the deposition of the section began at ～2.11 MaB.P..Based on the magnetostratigraphic study,combined with an analysis of the sedimentary characteristics and features of available Quaternary,sporopollen assemblages of the section,the authors think that the section records the paleoclimatic evolution in the basin since 2.11 MaB.P.and that the major epochs of paleoclimatic transition occurred at about 1.92,1.75,1.40,1.02 and 0.87 MaB.P.respectively.This is mainly the result of the long-distance effect of the strong uplift of the Qinghai-Tibet Plateau.Therefore,the establishment of the time sequence of paleoclimatic changes in the Gonghe basin should have certain significance for the study of the uplift of the Qinghai-Tibetan Plateau and its environmental effect,as well as the development of the Yellow River.",
        "keywords": [
            "northeastern margin of the Qinghai-Tibetan Plateau",
            "Quaternary",
            "Gonghe basin",
            "magnetostratigraphy"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Earth Science and Resources,China University of Geosciences,Beijing ;Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "MA Yin-sheng",
                "org": "School of Earth Science and Resources,China University of Geosciences,Beijing "
            },
            {
                "name": "WU Man-lu",
                "org": "School of Earth Science and Resources,China University of Geosciences,Beijing "
            },
            {
                "name": "ZHANG Yun-feng",
                "org": "Environmental Engineering Technology Center of China,National Petroleum Corporation,Beijing "
            },
            {
                "name": "DU De-ping",
                "org": "School of Earth Science and Resources,China University of Geosciences,Beijing "
            }
        ],
        "venue": "Journal of Geomechanics",
        "year": 2006
    },
    "3J4Tnjnu": {
        "id": "3J4Tnjnu",
        "title": "Observation of strong backward THz wave by mixing two infrared laser beams in GaSe",
        "abstract": "",
        "keywords": [
            "oscillations",
            "infrared"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": "lehigh university"
            },
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            }
        ],
        "venue": "Procedia Engineering",
        "year": 2004
    },
    "FP5VDfVs": {
        "id": "FP5VDfVs",
        "title": "Effect of Statin Therapy on Atrial Fibrillation",
        "abstract": "Statin therapy has been associated with reduced probability of developing atrial fibrillation(Af).The mechanism by which statins prevent Af is understood imcompletely.This article reviews the properties of statins which prevent Af as well as the possible mechanisms involved,including the modulation of transmembrane ion fluxes,the lowering of LDL-C levels,anti-inflammatory effects,the inhibition atrial remodelling and the improvement of autonomic function.",
        "keywords": [
            "atrial fibrillation",
            "statin",
            "mechanism",
            "statins"
        ],
        "authors": [
            {
                "name": "YIN Yue-hui",
                "org": "Department of Cardiology,The Second Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Cardiology,The Second Affiliated Hospital of Chongqing University of Medical Sciences,Chongqing ,China"
            }
        ],
        "venue": "Advances in Cardiovascular Diseases",
        "year": 2008
    },
    "Y5VZZp3Z": {
        "id": "Y5VZZp3Z",
        "title": "Assessment the quality of life in hemodialysis patients with SF-36",
        "abstract": "Objective To assess hemodialysis patients' quality of life and its influencing factors for improving quality of life in hemodialysis.Methods 165 hemodialysis patients,all on hemodialysis for over 3 months completed the SF-36 scales with self-administration.The means and deviations for each of eight scales were calculated,univariate analysis and multivariate regression were performed to determine the effect of variables such as age,gender,educational level,employment status,marital status,hemodialysis history,hemoglobin,co-existing diseases and so forth,on quality of life of the patients.Results The scores of the eight scales in the hemodialysis patients were 58.48±20.05,38.64±21.84,64.62±27.54,48.48±18.29,56.82±21.59,68.69±15.74,54.88±15.19,65.09±20.24.In the multip1e linear stepwise regression model of Physical Component Summary,four variables of gender,SGA score,cardiovascular disease and plasma albumin were included(P<0.05),while in that of Mental Component Summary,three variables of SGA score,gender and hemoglobin were included(P<0.05).Conclusion ①The quality of life in male hemodialysis patients is better than that in female.②The quality of life in hemodialysis patients with good nutritional condition is better than that of patient with malnutrition.③Complications have nagative effect on the quality of life of hemodialysis patients.",
        "keywords": [
            "Hemodialysis Quality of life Factor analysis SF-36 scales"
        ],
        "authors": [
            {
                "name": "MA Jian-chao",
                "org": ",et al.Department of Nephrology Guangdong Provincial People's Hospital Guangzhou,,China"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Department of Nephrology Guangdong Provincial People's Hospital Guangzhou,,China"
            },
            {
                "name": "WANG Wen-jian",
                "org": ",et al.Department of Nephrology Guangdong Provincial People's Hospital Guangzhou,,China"
            }
        ],
        "venue": "Guangdong Medical Journal",
        "year": 2007
    },
    "8t1oXVv3": {
        "id": "8t1oXVv3",
        "title": "Low friction of diamond sliding against Al 2 O 3 ceramic ball based on the first principles calculations",
        "abstract": "Abstract   Generally, amorphous carbon films sliding against Al 2 O 3  ceramic ball exhibited low friction. However, the low friction mechanism was still not well understood. Since the atomic interaction has difficulty in observing from the experimental method. Thus, in this paper, we probed the origin of low friction mechanism of amorphous carbon films against Al 2 O 3  ceramic ball based on first principles calculations. The work of separation did not well illustrate the low friction mechanism. The calculated results of the potential energy surface showed that the minimum energy paths, which defined as a series of low energy regimes of the potential energy surface, were in charge of the low friction.",
        "keywords": [],
        "authors": [
            {
                "name": "renhui zhang",
                "org": ""
            },
            {
                "name": "zhibin lu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "senlin leng",
                "org": ""
            },
            {
                "name": "bangcheng tang",
                "org": ""
            }
        ],
        "venue": "Surface & Coatings Technology",
        "year": 2015
    },
    "3FRUfgJb": {
        "id": "3FRUfgJb",
        "title": "Synthesis and biological evaluation of novel peptides based on antimicrobial peptides as potential agents with antitumor and multidrug resistance-reversing activities.",
        "abstract": "Tumor chemotherapy, which plays an important role in the clinical treatment of metastatic cancer, is limited by low selectivity and drug resistance in clinical application. In our study, we selected antimicrobial peptide BP100 as a lead peptide, designed, and synthesized a series of novel antineoplastic peptides through solid-phase synthesis. Among them, B4 and B8 showed excellent anticancer activity. As revealed by further investigations, these peptides could disrupt the cell membrane, trigger the cytochrome C release into cytoplasm, and ultimately lead to apoptosis. In addition, they also showed multidrug resistance-reversing effects by performing effective antitumor activity against multidrug-resistant cells. As a result, these peptides may possibly be regarded as a promising candidate for cancer treatment.",
        "keywords": [
            "anticancer",
            "antimicrobial peptides",
            "helix",
            "membrane disruption",
            "multidrug resistance-reversing effects"
        ],
        "authors": [
            {
                "name": "Bo Zhang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Jieming Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Chen Liao",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Limei Yang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Wenlong Huang",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, China."
            },
            {
                "name": "Hai Qian",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, Nanjing, China."
            }
        ],
        "venue": "Chemical biology & drug design",
        "year": 2017
    },
    "ErOQ2pRr": {
        "id": "ErOQ2pRr",
        "title": "NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice.",
        "abstract": "Podocyte injury plays a key role in the development of diabetic nephropathy (DN). We have recently shown that 11R-VIVIT, an inhibitor of cell-permeable nuclear factor of activated T-cells (NFAT), attenuates podocyte apoptosis induced by high glucose in vitro. However, it is not known whether 11R-VIVIT has a protective effect on DN, especially podocyte injury, under in vivo diabetic conditions. Hence, we examined the renoprotective effects of 11R-VIVIT in diabetic db/db mice and the possible mechanisms underlying its protective effects on podocyte injury in vivo and in vitro.Type 2 diabetic db/db mice received i.p. injections of 11R-VIVIT (1 mg·kg(-1)) three times a week and were killed after 8 weeks. Immortalized mouse podocytes were cultured under different experimental conditions.11R-VIVIT treatment markedly attenuated the albuminuria in diabetic db/db mice and also alleviated mesangial matrix expansion and podocyte injury. However, body weight, food and water intake, and glucose levels were unaffected. It also attenuated the increased NFAT2 activation and enhanced urokinase-type plasminogen activator receptor (uPA receptor) expression in glomerulor podocytes. In cultured podocytes, the increased nuclear accumulation of NFAT2 and uPA receptor expression induced by high glucose treatment was prevented by 11R-VIVIT or NFAT2-knockdown; this was accompanied by improvements in the filtration barrier function of the podocyte monolayer.The NFAT inhibitor 11R-VIVIT might be a useful therapeutic strategy for protecting podocytes and treating DN. The calcinerin/NFAT2/uPA receptor signalling pathway should be exploited as a therapeutic target for protecting podocytes from injury in DN.",
        "keywords": [
            "11r-vivit",
            "activate nuclear factor of activated t-cells",
            "diabetic nephropathy",
            "podocyte",
            "upar"
        ],
        "authors": [
            {
                "name": "Li Zhang",
                "org": "Southern Medical University, Guangzhou, China; Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China."
            },
            {
                "name": "Ruizhao Li",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Xinling Liang",
                "org": ""
            },
            {
                "name": "Shuangxin Liu",
                "org": ""
            },
            {
                "name": "Zhiming Ye",
                "org": ""
            },
            {
                "name": "Chunping Yu",
                "org": ""
            },
            {
                "name": "Yuanhan Chen",
                "org": ""
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Wenjian Wang",
                "org": ""
            },
            {
                "name": "Yuxiong Lai",
                "org": ""
            },
            {
                "name": "Jianchao Ma",
                "org": ""
            },
            {
                "name": "Zhuo Li",
                "org": ""
            },
            {
                "name": "Xiaofan Tan",
                "org": ""
            }
        ],
        "venue": "British journal of pharmacology",
        "year": 2013
    },
    "TJ8eUZ7i": {
        "id": "TJ8eUZ7i",
        "title": "The complete mitochondrial genome sequence of Brachirus orientalis (Pleuronectiformes: Soleidae).",
        "abstract": "Abstract The oriental sole Brachirus orientalis (Pleuronectiformes: Soleidae) is characterized by both eyes on the right side of the body and orbicular-ovate body. In this paper, the complete mitochondrial genome sequence of this sole was first determined. The total length is 16,602 bp, including 13 protein-coding genes, 22 tRNA genes, and 2 rRNA genes (12S and 16S), as well as a putative control region and a putative L-strand replication origin (OL). Gene contents, locations, and arrangements are identical to those of typical bony fishes. Overall base composition of the mitogenome is 30.4%, 28.6%, 15.3%, and 25.7% for A, C, G, and T, with a high A + T content (56.1%). The determination of B. orientalis complete mitogenome sequence could contribute to phylogenetic study on Soleidae and Pleuronectiformes.",
        "keywords": [
            "flatfish",
            "mitogenome sole",
            "teleost"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China."
            },
            {
                "name": "Li Gong",
                "org": ""
            },
            {
                "name": "Shu-Ying Wang",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2014
    },
    "d2Ereqps": {
        "id": "d2Ereqps",
        "title": "Signal bandwidth of general n×n multimode interference couplers",
        "abstract": "Analytical expression of signal bandwidth of general straight and tapered N/spl times/N multimode interference (MMI) couplers is presented. The signal bandwidth is characterized as a function of mode relative energy, mode propagation delay time, and mode pulse broadening in the multimode section of MMI coupler. The model is used to evaluate the signal bandwidth of specific couplers. Results indica...",
        "keywords": [
            "Bandwidth",
            "Interference",
            "Optical devices",
            "Optical crosstalk",
            "Optical interferometry",
            "Optical waveguides",
            "Optical fiber couplers",
            "Optical waveguide components",
            "Integrated optics",
            "Wavelength division multiplexing"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Inst. of Semicond., Acad. Sinica, Beijing, China"
            },
            {
                "name": "Jinzhong Yu",
                "org": ""
            },
            {
                "name": "Zhongli Liu",
                "org": ""
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Institut fur Informatik"
            },
            {
                "name": "Wei Shi",
                "org": "E.E. Dept"
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "Journal of Lightwave Technology",
        "year": 2001
    },
    "3bn8bsdm": {
        "id": "3bn8bsdm",
        "title": "Monitoring System of Electrical Network Parameter Based on Embeded Technology",
        "abstract": "Have brought forward one kind of Electrical network parameter monitoring system based on ARM series MPU(S3C4510B) and GPRS network.This paper introduces construction of hardware software function of the system.the high performance micropro- cessor S3C4510B is used and the embedded operation systemμC/OS2Ⅱis ported to it.And can realize the long range data corre- spondence through GPRS system.",
        "keywords": [
            "electrical network parameter",
            "communication protocol",
            "GPRS",
            "embedded system"
        ],
        "authors": [
            {
                "name": "Yang Benchen",
                "org": "Liaoning Technology University,Fuxin ,China"
            },
            {
                "name": "Li Lu",
                "org": "Liaoning Technology University,Fuxin ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Liaoning Technology University,Fuxin ,China"
            }
        ],
        "venue": "China New Telecommunications",
        "year": 2008
    },
    "qo5Esdzs": {
        "id": "qo5Esdzs",
        "title": "A Visualization Analysis of Hydrogen Electronic Cloud Distribution",
        "abstract": "With an aim at the abstract conception of wave functions for hydrogen atom in quantum mechanics,this paper suggests the radial distribution,angular distribution and spatial distribution function of hydrogen atom electronic cloud,and also,Matlab software is used to plot their corresponding distribution charts.The analytical results indicate that the distribution patterns of hydrogen atom electronic clouds are co-determined by the radial and angular probability distribution,and that the electronic cloud distribution density is so uneven that the orbit trace can be observed.Accordingly,this method can reveal the radial,angular and spatial probability distribution laws of hydrogen atom electronic clouds intuitionally,whereby a new thinking way for analyzing the abstract wave function visualization in quantum mechanics is provided in this paper.",
        "keywords": [
            "electronic cloud distribution",
            "visualization analysis",
            "Matlab software",
            "hydrogen atom"
        ],
        "authors": [
            {
                "name": "MA De-ming",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "QIU Hai-qiang",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2007
    },
    "1wAsv5aA": {
        "id": "1wAsv5aA",
        "title": "The Development of Running and Fault Information Management System for Generator Sets in Power Plant",
        "abstract": "This paper introduces the whole structure and components of TELEPROM ME DCS system,expounds the basic principles of system design,and describes software's functional module.",
        "keywords": [
            "generator sets in power plant",
            "functional module",
            "fault information management system"
        ],
        "authors": [
            {
                "name": "HE Hong",
                "org": ""
            },
            {
                "name": "GU Hong-bing",
                "org": ""
            },
            {
                "name": "YE Jun-ling",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "hTvIlQg4": {
        "id": "hTvIlQg4",
        "title": "Ultrasonic Distance Testing Control Design of Temperature Correction",
        "abstract": "On the basis of ultrasonic,the system referred in the paper uses DS1820 for temperature correction,so as to reach the measurement demand in different environment.This design can store,display and transmit data,and possess the characteristics of high precision and stable capability.In addition,it had been applied to a robot measurement system.",
        "keywords": [
            "distance testing",
            "ultrasonic",
            "design"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "MENG Jun",
                "org": "Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "LIU Bo",
                "org": "Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Mechanical Engineering & Automation",
        "year": 2005
    },
    "eEkJMCoS": {
        "id": "eEkJMCoS",
        "title": "Study on the Cross-platform Technology of Applied Software",
        "abstract": "This paper probes into the principles of the current cross-platform technologies such as Java virtual computer,Qt,and wxWidgets,etc.,and based on this,advances the idea of mid-level supporting structure to solve the simple multiplexing problem of the development of embedded software.",
        "keywords": [
            "virtual computer",
            "cross-platform technology",
            "Java"
        ],
        "authors": [
            {
                "name": "XU Chao-sheng",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "tiTXeXKt": {
        "id": "tiTXeXKt",
        "title": "Quenched-Domain Mode of Photo-Activated Charge Domain in Semi-Insulating GaAs Devices",
        "abstract": "The quenched domain mode of the photo-activated charge domain(PACD)in semi-insulating(SI)GaAs photoconductive semiconductor switches(PCSSs)is observed.We find that the quenched domain is induced by the instantaneous electric field across the PCSS being lower than the sustaining electric field of the domain during the transit of the domain.The extinction of the domain before reaching the anode can lead to a current oscillation frequency larger than the transit-time frequency when the bias electric field is lower than the threshold electric field of the nonlinear PCSS.According to the operation circuit and the physical properties of a high-field domain,an equivalent circuit of the quenched domain is presented.The equivalent circuit parameters including capacitance,resonant frequency,and inductance are calculated and measured.Our calculations agree well with the experimental results.This research provides theoretical and experimental criteria for heightening the oscillation frequency and efficiency of PACD devices.",
        "keywords": [
            "Equivalent-circuit",
            "Photoconducting switch",
            "Quenched domain mode"
        ],
        "authors": [
            {
                "name": "Tian Liqiang",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Semiconductors",
        "year": 2008
    },
    "NFd9elJ9": {
        "id": "NFd9elJ9",
        "title": "Variable corrosion behavior of a thick amorphous carbon coating in NaCl solution",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "renhui zhang",
                "org": ""
            },
            {
                "name": "liping wang",
                "org": "chinese academy of sciences"
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "RA2vKoMc": {
        "id": "RA2vKoMc",
        "title": "Design and Application of Solar Jointing Electric Heating Biogas Controller",
        "abstract": "In view of the problems of the low temperature in north China in winter,low gas digesters,the biogas cell body frost crack and so on,a solution of using solar jointing electric power for the digester heating was proposed.At first,in order to maintain the slurry temperature in suitable range and keep the fluctuation within ±3 ℃,the digesters and the surrounding soil were considered as an organic whole,a three-dimensional model of temperature control was established.Secondly,the software and hardware of the control system were designed in detail.Finally,the experiment was conducted using an intensive pig farm of 2 000 slaughter pigs per year in Harbin as an example.The results showed that the system needed to joint electric heating in the coldest four months and it could be powered by solar heating alone in other months,the temperature control accuracy of the system was within ±2 ℃.",
        "keywords": [
            "temperature control",
            "biogas",
            "solar energy"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,Liaoning,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin ,Liaoning,China"
            }
        ],
        "venue": "Hubei Agricultural Sciences",
        "year": 2011
    },
    "4TI9AoTe": {
        "id": "4TI9AoTe",
        "title": "Determination of moxifloxacin in human of pulse high volume hemofiltration serum urine and displacement liquid",
        "abstract": "Objective To determine the concentration of moxifloxacin in human's serum,urine and displacement liquid with pulse high volume hemofiltration(PHVHF) by high performance liquid chromatography(HPLC).Methods HPLC analysis was carried out by using yilite hypersil ODS-BP column(5 μm,4.6 mm × 150mm);The flow rate was 1.0 mL/min;The detecting wave length was at 290 nm.Results Among 8 cases,the average of BUN,Scr,K+ were significantly decreased(P < 0.05).The linearity of calibrated curves of serum sample was in the range of 0.1 ～ 10.0 mg/L r = 0.999 86,w = 1/C2.The method ological recovery of moxifloxacin was 98.7% ～ 101%.The within day RSDs and inter-day RSDs of were in the range of 1.12% ～ 5.7% of drug concentration in serum.The linearity of calibrated curves of displacement liquid sample was in the range of 0.1 ～ 10.0 mg/L r = 0.998 5.The method ological recovery of moxifloxacin was 85.7% ～ 95.7%.The within day RSDs and inter-day RSDs of were in the range of 1.34% ～ 8.9%.The linearity of calibrated curves of urine sample was in the range of 0.1 ～ 10.0 mg/L r = 0.986 8.The method ological recovery of moxifloxacin was 97.4% ～ 101.7%.The within day RSDs and inter-day RSDs of were in the range of 1.51% ～ 11.6%.Conclusions This method is rapid and accurate,which can be used for the pharmacokinetic study of moxifloxacin in serum and displacement liquid samples.",
        "keywords": [
            "Urine",
            "Moxifloxacin",
            "Chromatography",
            "Serum concentration",
            "Pulse high volume hemofiltration",
            "Displacement liquid",
            "high pressure liquid"
        ],
        "authors": [
            {
                "name": "LI Li",
                "org": "*Graduate Institute of Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "*Graduate Institute of Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "CHEN Tie-feng",
                "org": "*Graduate Institute of Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": "*Graduate Institute of Southern Medical University,Guangzhou ,China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2011
    },
    "cDg625ld": {
        "id": "cDg625ld",
        "title": "Vacancy defective perovskite Na 0.85 Ni 0.45 Co 0.55 F 3.56 nanocrystal anodes for advanced lithium-ion storage driven by surface conversion and insertion hybrid mechanisms.",
        "abstract": "A vacancy defective perovskite Na0.85Ni0.45Co0.55F3.56 nanocrystal (NNCF) has been introduced as an advanced anode for Li-ion capacitors (LICs), Li-ion batteries (LIBs) and Li-dual-ion batteries (Li-DIBs), exhibiting the surface conversion and insertion hybrid mechanisms for Li-ion storage.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Tong Yan",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Yuxi Huang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Caini Tan",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Xiujuan Sun",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Ping Gao",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, P. R. China. drm8122@xtu.edu.cn drm8122@163.com."
            }
        ],
        "venue": "Chemical communications (Cambridge, England)",
        "year": 2019
    },
    "n3UpLZyo": {
        "id": "n3UpLZyo",
        "title": "Circulating Current and Transient Ground Potential Rise Phenomenon on G S Enclosure",
        "abstract": "In recent years,GIS shows remarkable superiority by its application in power system.The substations with higher voltage level in China all use GIS form.The 1 000 kV substation which will soon be constructed should also use GIS form.The characteristics of the circulating current and transient ground potential rise on the metal enclosure are introduced.The mechanism,influencing factors,effect on secondary equipment and damage to personnel safety of the circulating current appeared on split continuous metal enclosure are analyzed.Meanwhile,the grounding mode used to reduce the circulating current is also discussed.",
        "keywords": [
            "circulating current",
            "gas-insulated switchgear(GIS)",
            "transient ground potential rise",
            "induced voltage",
            "metal enclosure"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "ZHANG Ya-ting",
                "org": ""
            },
            {
                "name": "LV Hong",
                "org": ""
            },
            {
                "name": "LI Wen-yi",
                "org": ""
            }
        ],
        "venue": "Shaanxi Electric Power",
        "year": 2008
    },
    "dqVTw5ht": {
        "id": "dqVTw5ht",
        "title": "Research on Response Property of Ultra-Short Electrical Pulse of Semi-Insulting GaAs Photoconductive Switches",
        "abstract": "The response properties of linear mode output ultra-short electric pulse are tested using the semi-insulating GaAs photoconductive switches triggered by 1064 nm laser pulse;and the tested experimental results are analyzed theoretically.Also,the changing laws of responsive properties of ultra-short electric pulse under the certain condition of bias voltage and triggering light energy are given.This paper points out that the main cause affecting the response properties of ultra-short electric pulse is due to the capture function of defect energy level and that the co-surface micro-carrying transmission line can produce no apparent effect upon ultra-short pulse waveforms.",
        "keywords": [
            "photoconductive switches",
            "defect energy level",
            "response property"
        ],
        "authors": [
            {
                "name": "DAI Hui-ying",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China;Faculty of Sciences,Air Force Engineering University,Xi'an ,China"
            },
            {
                "name": "MA De-ming",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2007
    },
    "byS5aM46": {
        "id": "byS5aM46",
        "title": "On the Relationship Between Innovative Education and the Combination of Production, Teaching and Research",
        "abstract": "In this paper, the combination of production, teaching and research and the basic links of innovative education are introduced, and their inter-relationship stressed, which indicates the basic rules of how the combination of production, teaching and research will promote the educational innovation.",
        "keywords": [
            "combination of production",
            "innovative education",
            "teaching and research",
            "Innovative ability"
        ],
        "authors": [
            {
                "name": "SONG Yue",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "TAN Ai-qun",
                "org": ""
            },
            {
                "name": "YU Chi-ye",
                "org": ""
            },
            {
                "name": "LI Lin",
                "org": ""
            }
        ],
        "venue": "Journal of Dongguan University of Technology",
        "year": 2006
    },
    "tZ9HU2eY": {
        "id": "tZ9HU2eY",
        "title": "Clinical Research of Aristolochid Acid Nephropathy Treated with Jiaweifuzilizhongtang",
        "abstract": "Objective To investigate the effects on the renal function and the clinical symptoms of patients with aristolochic acid nephropathy (AAN) treated with the Chinese herbal medicine, Jiaweifuzilizhongtang. Method Twenty-seven patients with AAN were treated with Jiaweifuzilizhongtang. The indexes, such as blood urea nitrogen (BUN), serum creatinine (SCr), endogenous creatinine clearance rate (CCr), twenty-four-hour proteinuria quantitate (24 h Upo), β-N-acetyglocosamidase (NAG), Urine Osmol (Uosm), erythrocyte (RBC), hemoglobin (HB) and so on, were observed before and after treatment, and the score of patients’ symptoms including aversion to cold and cold limbs, lassitude and weakness, poor appetite and anorexia, nausea and vomiting, pale complexion, was also calculated. Result Compared with that of treatment bebore, the renal function of patients after treatment was significantly improved (P <0.05) according to the indexes of BUN, SCr, CCr, 24 h Upro, NAG, Uosm, RBC and HB; Meanwhile, the score of clinical symptoms after treatment was obviously different (P <0.05) from that of treatment before, and the total clinical effective rate was 74.07%. Conclusions Chinese herbal medicine, Jiweifuzilizhongtang, can effectively treat the patients with aristolochic acid nephropathy (AAN).",
        "keywords": [
            "clinical research",
            "aristolochic acid nephropathy",
            "Jiaweifuzilizhongtang"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "The First Affiliated Hospital of Guangxi College of TCM, Nagning , China"
            },
            {
                "name": "XIANG Cai-chun",
                "org": "The First Affiliated Hospital of Guangxi College of TCM, Nagning , China"
            },
            {
                "name": "XIE Yong-xiang",
                "org": "The First Affiliated Hospital of Guangxi College of TCM, Nagning , China"
            }
        ],
        "venue": "Chinese Journal of Information on Traditional Chinese Medicine",
        "year": 2006
    },
    "Of4NfJh0": {
        "id": "Of4NfJh0",
        "title": "MULTI-CHIP ASSEMBLY WITH OPTICALLY COUPLED DIE",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qing a zhou",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "xiang yin zeng",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "0H9WZaGf": {
        "id": "0H9WZaGf",
        "title": "Docking and CoMSIA studies on steroids and non-steroidal chemicals as androgen receptor ligands.",
        "abstract": "While some synthetic chemicals have been demonstrated to disrupt normal endocrine function by binding to the androgen receptor (AR), the mechanism by which ligands bind to the ligand binding domain (LBD) remained unclear. In this study, docking and comparative molecular similarity index analysis (CoMSIA) were performed to study the AR ligand binding mechanism of steroids and non-steroidal chemicals. The obtained docking conformations and predictive CoMSIA models (r(pred)(2)values as 0.842 and 0.554) indicated the primary interaction site and key residues in the binding process. The major factors influence the binding affinity of steroids and non-steroidal chemicals were electrostatic and hydrophobic interactions, respectively. The results indicated that besides amino-acid residues Gln711, Arg752 and Thr877 which have previously been reported to be important in binding ligands, Leu701 and Leu704 are also important. Residues Val746, Met749 and Phe764 are crucial only for steroids, while Met742 and Met787 are important only for non-steroidal chemicals. This knowledge of key interactions and important amino-acid residues governing ligands to the AR allow better prediction of potency of AR agonists so that their potential to disrupt AR-mediated pathways and to design less potent alternatives.",
        "keywords": [
            "non-steroidal androgens",
            "steroids",
            "androgen receptor",
            "docking",
            "comsia"
        ],
        "authors": [
            {
                "name": "Xiaoxiang Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiaolin Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "John P Giesy",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Yulei Wang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2013
    },
    "xla7ujy4": {
        "id": "xla7ujy4",
        "title": "Effects of C-reactive protein on renal function of chronic kidney disease and its mechanism",
        "abstract": "Objective To investigate the effect of C-reactive protein (CRP) on progression of chronic kidney disease (CKD). Methods Serum level of CRP and renal function parameters were determined in 56 CKD patients without hemodialysis,and the correlations between them were analyzed. Also,in vitro experiments were conducted to observe the secretion of transforming growth factor β1 (TGF-β1) and extracellular matrix of collagen Ⅰ (Col Ⅰ) and collagen Ⅳ (Col Ⅳ) in cultured human proximal tubular epithelium cell line HK-2 induced by CRP. Results The serum level of CRP was increased with the worsening of renal function,and was negatively correlated with glomerular filtration rate (r = -0.648,P < 0.001). Stimulated by CRP in vitro,the levels of TGF-β1,Col Ⅰ,and Col Ⅳ in the supernatant of HK-2 cells were increased in a dose-and time-dependent manner in comparison with control group (P < 0.001). Conclusion Elevated CRP may contribute to the progression of CKD through stimulating the synthesis and secretion of extracellular matrix by renal tubular epithelial cells.",
        "keywords": [
            "Kidney disease",
            "Tubular epithelial cells",
            "Extracellular matrix",
            "Transforming growth factor β1",
            "C-reactive protein"
        ],
        "authors": [
            {
                "name": "XIE Kai-qing",
                "org": ". Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": ". Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "LI Dong-feng",
                "org": ". Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "XIA Yun-feng",
                "org": ". Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "YANG Yun",
                "org": ". Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Southern Medical University,Guangzhou ,China"
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2010
    },
    "cmVULXt7": {
        "id": "cmVULXt7",
        "title": "Using DNA data to determine the taxonomic status of Ammopiptanthus kamelinii in Kyrgyzstan (Thermopsideae, Leguminosae)",
        "abstract": "The taxonomic status of  Ammopiptanthus   kamelinii  has been unresolved because of numerous characters that make it similar to another closely related species,  A. nanus . In this study, we set out to resolve the complex relationships among  A. kamelinii  using samples from three populations, with a total of 38 individuals. Phenotypic indices (plant height, canopy, and leaf characters) and DNA data (ITS 1–4 nrDNA markers, as well as  trnH-psbA ,  trnL-trnF , and  trnS-trnG  cpDNA markers) were used to understand the controversial taxonomic status of  A. kamelinii . The phenotypic characters of  A. kamelinii  did not show a significant difference from  A. nanus , and the nrDNA data did not reflect any variability from  A. nanus , but all the individuals of  A.   kamelinii  in Kyrgyzstan showed two new haplotypes in the cpDNA. When the genetic data were combined, specimens of  A. kamelinii  clustered together with  A. nanus ; therefore, we have confirmed that  A. kamelinii  cannot be recognized as a separate species of  A. nanus  and should be merged with the latter species. The description of  A. nanus  is revised here.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Zhihao Su",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Borong Pan",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Shixin Wu",
                "org": "Xinjiang Institute of Ecology and Geography, The Chinese Academy of Sciences, Xinjiang, 830011 Urumqi, China"
            }
        ],
        "venue": "Phytotaxa",
        "year": 2018
    },
    "SyeEsNIK": {
        "id": "SyeEsNIK",
        "title": "Four branches of star connection MOA module in electro-magnetic transient calculation",
        "abstract": "This paper describes four branches of star connection MOA module in electro-magnetic transient program (EMTP). With this module, phase-to-ground and phase-to-phase over voltage suppressed by star connection MOA can be accurately calculated. In star connection MOA designs, it becomes a powerful tool to choose the best parameter for the coordination between the upper elements and the lower elements of MOA.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Xiaomin Niu",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yunge Li",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 1995
    },
    "8A2PkYTe": {
        "id": "8A2PkYTe",
        "title": "Fluorine effect on adhesion and adhesive transfer at iron/diamond interfaces",
        "abstract": "Abstract   In this work, using a first principles methodology, the fluorine terminated diamond surfaces were selected to understand the adhesion between iron and fluorine terminated diamond interfaces. In order to minimize the lattice mismatch between the iron and diamond, the fcc Fe was used in this investigation. We find that F atoms transferring to Fe surface facilitates the graphitization of fluorine-free diamond surface. Graphitization could well illustrate the tribological properties of iron and fluorine terminated diamond interfaces. The calculated results were well in consistence with the experiments.",
        "keywords": "",
        "authors": [
            {
                "name": "Renhui Zhang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Yingchang Yang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Senlin Leng",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, Tongren University, Tongren, 554300, PR China"
            }
        ],
        "venue": "Computational Condensed Matter",
        "year": 2017
    },
    "opGaomIx": {
        "id": "opGaomIx",
        "title": "Understanding the friction behavior of sulfur-terminated diamond-like carbon films under high vacuum by first-principles calculations",
        "abstract": "Abstract   Generally, the repulsive force was a key factor account for superlow friction of H or F doped diamond-like carbon (DLC) films under high vacuum. As we known, H or F doped DLC usually exhibited superlow friction under high vacuum. However, the superlow friction of S doped DLC under high vacuum was not found so far. This phenomenon was desirable to be well investigated. In this work, S-terminated diamond interfaces also exhibited strong repulsive force, however, the estimated friction coefficient was variable for S-terminated diamond interfaces. The lowest and largest friction coefficient was about 0.003 and 0.4 respectively, which indicated that the superlow friction of S doped DLC could achieve in theory. In order to well probe the unusual friction behavior of S doped DLC under high vacuum, using first-principles method, the repulsive interaction between sliding surfaces was well investigated in order to understand the unusual friction behavior of S doped DLC films.",
        "keywords": "",
        "authors": [
            {
                "name": "Renhui Zhang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, TongRen University, Tongren 554300, PR China"
            },
            {
                "name": "Juan Zhao",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, TongRen University, Tongren 554300, PR China"
            },
            {
                "name": "Yingchang Yang",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, TongRen University, Tongren 554300, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Research Center of Material and Chemical Engineering, School of Material and Chemical Engineering, TongRen University, Tongren 554300, PR China"
            },
            {
                "name": "Zhibin Lu",
                "org": ""
            },
            {
                "name": "Junjun Wang",
                "org": "College of Materials Science and Engineering, Chongqing University of Technology, Chongqing 400054, PR China"
            }
        ],
        "venue": "Current Applied Physics",
        "year": 2018
    },
    "cRCAhWGJ": {
        "id": "cRCAhWGJ",
        "title": "Characterization and Synthesis of Polyterthiophenes Containing 3,4-Ethylenedioxythiophene(EDOT)",
        "abstract": "An ethylenedioxy group substituted terthiophene derivative(3′,4′-ethylenedioxy-2,2′∶5′,2″-terthiophene,TET) was synthesized via Stille reaction,and the related polythiophene derivatives(poly(3′,4′-ethylenedioxy-2,2′∶5′,2″-terthiophene),PTET) were obtained by oxidation polymerization with different dosage of FeCl_3 as catalysts at 0—5 ℃.These polymers were characterized by UV-Vis、FT-IR GPC、CV、TEM and TGA analysis.The number average molecular weights(M_n) of these polymers are 3.4×10~3—3.6×10~3.These polymers exhibit good thermal stability with thermal decomposition temperatures above 110 ℃.UV-Vis spectroscopy indicates low bandgaps(2.05 eV) of these polymers,and the maximum absorption is 466—474 nm.",
        "keywords": [
            "4′-ethylenedioxy-2",
            "2″-terthiophene)",
            "2′∶5′",
            "poly(3′",
            "FeCl_3",
            "oxypolymerization"
        ],
        "authors": [
            {
                "name": "ZHAO Chun-bao",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "YAO Mei-qin",
                "org": "School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Polymers",
        "year": 2009
    },
    "0YThGPM2": {
        "id": "0YThGPM2",
        "title": "Investigation of the new guest-host DR13/PEK-c poled polymer",
        "abstract": "The films of polyetherketone doped with DR13 were prepared, the electro optic (EO) coefficient is measured by a using an interferometric technique, and the thermal stability was demonstrated by the time dependence of the piezoelectricity.",
        "keywords": [
            "electro optic coefficient measurement",
            "piezoelectricity",
            "electro-optical effects",
            "dr13 doped polyetherketone films",
            "guest-host dr13/pek-c poled polymer",
            "optical polymers",
            "eo coefficient",
            "interferometric technique",
            "dielectric polarisation",
            "optical films",
            "light interferometry",
            "time dependence",
            "thermal stability",
            "voltage",
            "corona",
            "absorption",
            "glass"
        ],
        "authors": [
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Lasers and Electro-Optics, 2001. CLEO/Pacific Rim 2001. The 4th Pacific Rim Conference",
        "year": 2001
    },
    "96RH1y3u": {
        "id": "96RH1y3u",
        "title": "Investigation of ultra-fast accurately synchronization control GaAs photoconductive switches",
        "abstract": "Experiments of a lateral semi-insulating GaAs photoconductive semiconductor switch triggered by nanosecond serial laser pulses were reported. The switches were insulated by solid multi-layer transparent dielectrics. Jitter-free electrical pulses with steady voltage amplitude from the 0.5 mm-gap GaAs switches were observed. Its change of amplitude was less than 1.1%, the triggered jitter-time was less than 10ps, and pulse width was up to sub-nanosecond. The Jitter-free and steady speciality of electrical pulses from the photoconductive semiconductor switch was analyzed. It was indicated that ultra-fast electrical pulse with steady voltage amplitude and pico-second triggered jitter-time can be obtained by controlling switch trigger condition and optimizing switch design. © 2008 SPIE.",
        "keywords": [
            "photoconductive switch",
            "pico-second triggered jitter-time",
            "semi-insulating gaas",
            "stability of pulse voltage amplitude",
            "ultra-fast electrical pulse",
            "gallium arsenide",
            "switches",
            "lasers",
            "dielectrics",
            "semiconductors"
        ],
        "authors": [
            {
                "name": "Ma Deming",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Shi Wei",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Xue Hong",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Li Xiaolong",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2008
    },
    "4niU9noi": {
        "id": "4niU9noi",
        "title": "Archaeological sites,buried peat and fluctuation of sea-level in Holocene in the Ningshao Plain in Zhejiang Province,China",
        "abstract": "",
        "keywords": [
            "fluctuation of sea-level",
            "initial residence-surface",
            "Ningshao Plain in Zhejiang Province",
            "\"event layers\"",
            "Middle Holocene",
            "buried peat",
            "China"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Institute of Oceanology & Geography Sciences, Nanjing University, Nanjing , China; Department of Geo-graphy, Jiangsu Province Institute of Education, Nanjing , China"
            },
            {
                "name": "MA Chun-mei",
                "org": "Institute of Oceanology & Geography Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "JIAO Feng",
                "org": " Department of Environmental Science and Engineering, Suzhou Institute of Science & Technology, Suzhou , China"
            },
            {
                "name": "ZHU Cheng",
                "org": "Institute of Oceanology & Geography Sciences, Nanjing University, Nanjing , China"
            },
            {
                "name": "WANG Fu-bao",
                "org": "Institute of Oceanology & Geography Sciences, Nanjing University, Nanjing , China"
            }
        ],
        "venue": "Acta Oceanologica Sinica",
        "year": 2008
    },
    "B6oJRDAi": {
        "id": "B6oJRDAi",
        "title": "Study on Jurassic Superposed Deformation in Yudu Area Located in the Middle of Dabashan Tectonic Belt",
        "abstract": "Dabashan tectonic belt characterized by thrust nappe structure is developed in the southern of Qinling orogenic belt.Through detailed structural analysis in Yudu area located in the middle of Dabashan tectonic belt,the results show that Dabashan tectonic belt has undergone at least two superposed deformation since Jurassic.The deformed strata are Triassic Jialingjiang Formation to Jurassic Shaximiao Formation.Early deformation is predominantly NW-NNW axes trending box fold or partition wall style fold and decollement structure developed at deep.The time of early deformation is late Jurassic to early Cretaceous.The late deformation relates to thrust movement of its north side and results in dextral strike slipping deformation which composed of dextral strike slipping fault and NW-NNW trending tight folds.The time of late deformation is between late Jurassic and early Cretaceous.Folds formed by two stages deformation have similar extend direction and are consistent with the direction of regional tectonic line.Away from the northern Zhenba fault,the deformation intensity has a weaken tendency.The two stage deformations form coaxial or oblique superimposed structure.Study shows that the deformation relates to the southward thrusting of Dabashan thrust nappe belt.",
        "keywords": [
            "box fold",
            "superposed deformation",
            "foreland tectonic belt",
            "Qinling",
            "Dabashan"
        ],
        "authors": [
            {
                "name": "WU Guo-li",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "CHEN Hong",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "TIAN Mi",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "GAO Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Earth Sciences and Environment",
        "year": 2010
    },
    "3ImNmkaV": {
        "id": "3ImNmkaV",
        "title": "An Experimental Research About the Memory Effect of Self-Esteem:The Cognitive Processing Mechanism",
        "abstract": "The research explored the cognitive processes of the memory effect of self-esteem.In Experiment 1,every adjective was randomly presented to 89 college student subjects by computer for either an ample(4s) or limited(1s) time interval.In Experiment 2,the computer automatically recorded the time interval of 82 subjects' s reading about every adjective.The results showed that the underlying cognitive processes of the memory effect of self-esteem were the different allocation of processing time for different information at the encoding phase,rather than self-esteem's automatically processing.Specifically,high self-esteem individuals allocated fewer processing time for negative information,resulting in shallow processing for the information,which is the so-called neglect.But low self-esteem individuals had the same processing level,resulting in no difference between the recall of positive information and negative information.",
        "keywords": [
            "self-esteem's memory effect",
            "actual processing time",
            "selective attention",
            "processing mechanism",
            "self-schema"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "1 School of Culture and Social Development Studies,Southwest University,Chongqing,"
            },
            {
                "name": "Huang Gang",
                "org": "1 School of Culture and Social Development Studies,Southwest University,Chongqing,"
            }
        ],
        "venue": "Psychological Science",
        "year": 2009
    },
    "lhlbzawA": {
        "id": "lhlbzawA",
        "title": "Influence of Axial Compression Ratio to the Seismic Collapse Resistance of RC Frame Structures",
        "abstract": "The seismic collapse resistances of 24 reinforced concrete(RC) frame structures(in 7-degree seismic intensity zone,with different span,storey height and storey number) which are designed according to the Chinese Seismic Design Code are analyzed with fiber-beam element model and incremental dynamic analysis(IDA) that is recommended by ATC-63 Report.The results show that the axial compression ratio of columns is the most important factor affecting seismic collapse resistance of these structures and there is a negative linear correlation between axial compression ratio of columns and collapse margin ratio of structures.The upper limit of current seismic design code is too big which mostly results in the lack of collapse resistance of frame structures.Then,the axial compression ratio of all structures is unified by adjusting their column size and the modified structures are analyzed again,which show that by controlling the axial compression ratio,the seismic collapse resistance is obviously improved.",
        "keywords": [
            "axial compression ratio",
            "collapse probability",
            "frame structure",
            "incremental dynamic analysis",
            "collapse performance"
        ],
        "authors": [
            {
                "name": "Tang Dai-yuan",
                "org": "Department of Civil Engineering,Tsinghua University,Key Laboratory of Structural Engineering and Vibration of China Education Ministry,Beijing ,China"
            },
            {
                "name": "Lu Xin-zheng",
                "org": "Department of Civil Engineering,Tsinghua University,Key Laboratory of Structural Engineering and Vibration of China Education Ministry,Beijing ,China"
            },
            {
                "name": "Ye Lie-ping",
                "org": "Department of Civil Engineering,Tsinghua University,Key Laboratory of Structural Engineering and Vibration of China Education Ministry,Beijing ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Civil Engineering,Tsinghua University,Key Laboratory of Structural Engineering and Vibration of China Education Ministry,Beijing ,China"
            }
        ],
        "venue": "Earthquake Resistant Engineering and Retrofitting",
        "year": 2010
    },
    "CJAJJUsI": {
        "id": "CJAJJUsI",
        "title": "Prospective study for prognostic value of serum cystatin C in acute renal failure",
        "abstract": "AIM: To study the level of serum cystatin C ( Cys C) and its prognostic value in acute renal failure (ARF). METHODS: 215 critically ill patients were studied prospectively, and each blood sample was determined daily. Serum creatinine (Scr) was measured by enzymic method. Cys C was detected by particle-enhanced turbidimetric immunoassay (PETIA) and glomerular filtration rate (GFR) was estimated by Cockroft-Gault equation. ARF was diagnosed according to ADQI (RIFLE) criteria. RESULTS: 41 patients developed ARF to some degree, among which 7, 13 and 21 patients fulfilled R-, I-, and FLE-criteria, respectively. 21 were death and 20 survival in total 41 ARF patients. 174 patients without ARF served as controls. In patients with ARF, Cys C was significantly increased than that in patients who did not develop ARF (P<0.01). In different RIFLE criteria of ARF, serum Cys C was linearly correlated with serum creatinine (P<0.01), also [ Cys C] -1 with estimated GFR (P<0.01). When ARF was diagnosed according to serum creatinine increased ≥150%, serum Cys C was demonstrated a highly diagnostic value to detect ARF as indicated by area under the curve (AUC) of the ROC curve of 0.983 (95% confidence interval, 0.960-1.006) (P<0.01). Logistic regression showed serum Cys C and Scr were not independently risk factors for the mortality of ARF (P>0.05). Also ROC analysis demonstrated serum Cys C and Scr had no predicting value of the fatality and survival in ARF (P>0.05). CONCLUSION: Serum Cys C is significantly increased in ARF and correlated well with the severity of ARF. Serum Cys C can be one of the detectable markers of ARF, but it is independent of the mortality and does not predict the prognosis of these patients.",
        "keywords": [
            "Cysteine proteinase inhibitors",
            "Kidney failure",
            "Prognosis",
            "acute"
        ],
        "authors": [
            {
                "name": "LIANG Xin-ling",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "SHI Wei",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "YE Zhi-ming",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "ZENG Hong-ke",
                "org": "2Department of Intensive Care Medicine, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "PENG Yan-qiang",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "HE Chao-sheng",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "HU Xiang-ming",
                "org": "1Department of Nephrology,"
            },
            {
                "name": "WANG Wen-jian",
                "org": "1Department of Nephrology,"
            }
        ],
        "venue": "Chinese Journal of Pathophysiology",
        "year": 2006
    },
    "dt4Dcsgn": {
        "id": "dt4Dcsgn",
        "title": "Variety Comparison Test of Introduced Wheat in Hilly Area in Rong County",
        "abstract": "according to climate and topography of Rong county,those are investigated and analyzed yield traits and external agronomy character of four foreign wheat breeds,China Ⅰ,InitiateⅠ,Initiate Ⅱ,685-25-1,and one wheat breed,107,in Sichuan province,in order to prepare to select suitable wheat breed.",
        "keywords": [
            "Introduction",
            "Hills region in Rong county",
            "Wheat"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Chengdu Vocational College of Agricultural Science and Technology,Chengdu ,China"
            }
        ],
        "venue": "Inner Mongolia Agricultural Science and Technology",
        "year": 2010
    },
    "i1Oejq7u": {
        "id": "i1Oejq7u",
        "title": "Study on transmission of terahertz wave in plasma",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "suguo chen",
                "org": ""
            },
            {
                "name": "lei hou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "nzJxUojd": {
        "id": "nzJxUojd",
        "title": "Dipstick proteinuria is a prognostic indicator of short-term mortality in patients with heart failure.",
        "abstract": "Our results demonstrate that proteinuria correlates with the short-term mortality rate of patients hospitalized for AHF. Dipstick proteinuria testing might represent a promising prognostic indicator for these patients.",
        "keywords": [
            "acute heart failure",
            "marker",
            "mortality",
            "prognostic indicator",
            "proteinuria"
        ],
        "authors": [
            {
                "name": "Yuanhan Chen",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Lu Cai",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Zhiming Du",
                "org": "Department of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China."
            },
            {
                "name": "Jiaqi Xu",
                "org": "Department of Nephrology, Huadu District, Guangzhou City People's Hospital, Guangzhou, 510080, China."
            },
            {
                "name": "Ning Tan",
                "org": "Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Zhiming Ye",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Shuangxin Liu",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Wei Dong",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China."
            },
            {
                "name": "Wei Shi",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China. Electronic address: ssweicn@163.com."
            },
            {
                "name": "Xinling Liang",
                "org": "Divisionof Nephrology, Guangdong General Hospital, Guangdong Academic of Medical Sciences, Guangzhou, 510080, China. Electronic address: xinlingliang@139.com."
            }
        ],
        "venue": "International journal of cardiology",
        "year": 2017
    },
    "h2zqbcYO": {
        "id": "h2zqbcYO",
        "title": "A Review of Research about Workaholism",
        "abstract": "The study of workaholism was reviewed in this article. Workaholism involves difficult disengaging from work, a strong drive to work, intense enjoyment of work, and additional devotement much time and energy to work. The paradigms employed to explain workholism include addiction model, reinforcement theory, trait-based paradigm, and, more recently, family-systems model. The importance of measurement validation has been one that has plagued the early development of workaholism research. Currently, there are three validated measures of workaholism: Work Addiction Risk Test, Workholism Battery and Workholic Behavior Scale. Some of researches have focused on dealing with antecedents of workholism, such as personality, demographic variables and organizational factors, and the consequences of workaholism include health and relationship. The workaholism research arena is still in its infancy, thus, there is ample opportunity to develop the concept and theoretically integrated research programmes, also the measurement and sampling research in the future.",
        "keywords": [
            "WorkBAT.",
            "addiction model",
            "workaholism",
            "trait-based paradigm"
        ],
        "authors": [
            {
                "name": "LIU Jie",
                "org": "School of Culture and Social Development Studies, Southwest University, Chongqing , China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies, Southwest University, Chongqing , China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2008
    },
    "Vk4Pv6nZ": {
        "id": "Vk4Pv6nZ",
        "title": "Measurement of the optical transmission modes and losses of the poled guest–host polymer NAEC/PEK-c planar waveguides",
        "abstract": "The polyetherketone (PEK-c) guest–host polymer planar waveguides doped with (4′-nitro)-3-azo-9-ethyl-carbazole (NAEC) were prepared. The waveguide films were poled by corona-onset poling at elevated temperature (COPET), and the corona poling setup includes a grid voltage making the surface-charge distribution uniform. By using the prism-in coupling method, the dark-line spectrum given by the reflected intensity versus the angle of incidence have been obtained, and the optical transmission losses of m th modes have been measured for the poled polymer waveguides at λ =632.8 nm. The measurement result showed that the optical loss of the fundamental mode is less than 0.7 dB cm −1 for the TE polarization. Keywords Polymer waveguide Poling Transmission mode Optical loss",
        "keywords": [
            "spectrum"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Feng Li",
                "org": "Department of Chemistry, Jilin University, Changchun 130023, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Hongzheng Wei",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Optics and Lasers in Engineering",
        "year": 2000
    },
    "xceAebBA": {
        "id": "xceAebBA",
        "title": "The complete mitochondrial genome sequence of Pelates quadrilineatus (Perciformes: Terapontidae)",
        "abstract": "AbstractThe complete mitochondrial genome of marine fish Pelates quadrilineatus was sequenced by the high throughput sequencing method. This genome was 16,823 bp in length, consisted of 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. The gene arrangement of P. quadrilineatus is identical to those of other fishes. Phylogenetic tree based on 13 protein coding genes shows that Terapontidae has a closer phylogenetic relationship to Pentacerotidae than to Chaetodontidae.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Shixi Chen",
                "org": " CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China"
            },
            {
                "name": "Hui Yu",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "0J4nApvK": {
        "id": "0J4nApvK",
        "title": "Electrical network load forecast model research based on artificial immunization algorithm",
        "abstract": "In order to overcome defects existing in some aspects of network structure design and convergence effect in traditional methods of neural network forecast,a new algorithm,that is artificial immunization algorithm,was proposed to make prediction of eletric system load.This algorithm is designed according to the mechanism of immunization system of advanced animals,which regards objective function and part of inequaltiy constraint condition as antigen,and consider the solution of searching space as antibody.Based on bonding force between antigen and antibody and among antibodies,the solution was chosen;by motivate inter-action among antibodies the searching efficiency near optimal point was improved;and by memerizing the depression of cell to antibodies regional optimal point can be gottenrid of effectively.This model was applied to load forecast practice in Fuxin region,which shows that compared with traditional forecast methods of neural network this model has more powerful self-adaptive ability and better effects.",
        "keywords": [
            "artificial immunization system",
            "neural network",
            "forecast",
            "electrical network load"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "College of Industrial and Commercial Management,Liaoning Technical University,Fuxin ,China"
            },
            {
                "name": "LIU Jian-hui",
                "org": "College of Industrial and Commercial Management,Liaoning Technical University,Fuxin ,China"
            }
        ],
        "venue": "Journal of Anshan University of Science and Technology",
        "year": 2006
    },
    "J95lsPCo": {
        "id": "J95lsPCo",
        "title": "Fabrication of 4 x 4 tapered MMI coupler with large cross section",
        "abstract": "MMI coupler with large cross section has low coupling loss between the device and fiber. However, large chip area is required. Recently proposed N/spl times/N tapered MMI coupler shows a substantial reduction in device geometry. No such kind of devices with N>2 has yet been realized up to now. The authors have demonstrated a 4/spl times/4 parabolically tapered MMI coupler with large cross section ...",
        "keywords": [
            "Fabrication",
            "Silicon on insulator technology",
            "Optical fiber couplers",
            "Optical fiber devices",
            "Integrated circuit technology",
            "Geometry",
            "Coupling circuits",
            "Samarium",
            "Optical losses",
            "Integrated optics"
        ],
        "authors": [
            {
                "name": "hongzhen wei",
                "org": "Inst. of Semicond., Acad. Sinica, Beijing, China"
            },
            {
                "name": "jinzhong yu",
                "org": ""
            },
            {
                "name": "zhongli liu",
                "org": ""
            },
            {
                "name": "xiaofeng zhang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "changshui fang",
                "org": ""
            }
        ],
        "venue": "IEEE Photonics Technology Letters",
        "year": 2001
    },
    "vTfjbarI": {
        "id": "vTfjbarI",
        "title": "Giant spinal cord ependymoma with CSF spread.",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Xing Su",
                "org": "ntchenjian9079@163.com"
            },
            {
                "name": "Qing-Feng Huang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Jian-Guo Chen",
                "org": ""
            },
            {
                "name": "Jian Chen",
                "org": ""
            }
        ],
        "venue": "Neurology",
        "year": 2012
    },
    "A7IM0fGS": {
        "id": "A7IM0fGS",
        "title": "Formation Mechanism of the Dabashan Foreland Arc-Shaped Structural belt",
        "abstract": "Based on field observations and structural measurements,this paper describes basic features of the Dabashan foreland arc-shaped structural belt,its distribution pattern,zonation,segmentation,vertical stratification,deformation pattern,superimposed folding and paleostress field,then discusses main factors controlling the formation of this structural arc. It pointed out that the formation and development of the Dabashan foreland arc are different from classical model of collisional mountain built-up; it was shaped through three different stages:original boundary conditions formed during Paleozoic extension and rifting along the marginal zone of the Yangze; initiation during Middle-Late Triassic collisional orogen; and final formation during Middle-Late Jurassic intra-continental orogen. The arc-shaped Chengkou-Fangxian fault zone not only controls the Early Paleozoic deposition and magmatism,but also played key role in the foreland arc formation,and the basement uplifts at the two syntax acted as important boundary conditions. Sandbox modeling was carried out in the laboratory to model the formation and boundary condition of the Dabashan foreland arc. The model was set-up according to the real geologic data.",
        "keywords": [
            "tectonophysical modeling",
            "Dabashan foreland arc-shaped belt",
            "Paleostress field",
            "superimposed fold",
            "deformation pattern"
        ],
        "authors": [
            {
                "name": "ZHANG Yueqiao",
                "org": ")1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "SHI Wei",
                "org": ")1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "LI Jianhua",
                "org": ")1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "WANG Ruirui",
                "org": " Earth Science Department,Nanjing University,Nanjing,"
            },
            {
                "name": "LI Hailong",
                "org": ")1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing,"
            },
            {
                "name": "DONG Shuwen",
                "org": " Chinese Academy of Geological Sciences,Beijing,"
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2010
    },
    "lCCkTW4J": {
        "id": "lCCkTW4J",
        "title": "Structure and Photoelectron Energy Spectrum of Ga_2As_n Ion Clusters",
        "abstract": "The method of B3LYP/6-311G(d) in density functional theory (DET)was used to optimize the geometric configuration and study the photoelectron energy spectrum of Ga_2As_n (n=1-5) ion clusters. The ground-state structure of the clusters has been obtained, the stability of which shows a certain degree of even/odd alternation with the increase of the total atoms number. The structure with odd number of total atoms is more stable than those with even number of total atoms in Ga_2As_n~- clusters, while it is quite the contrary in Ga_2As_n~+ clusters. The energy gap between the highest-occupied molecular orbital (HOMO) and the lowest-unoccupied molecular orbital (LUMO) displays a certain degree of even/odd alternation, with the increase of the arsenic atoms number. The energy gap values with even number of arsenic atoms are basically the same, but they are rather different with odd number of arsenic atoms.",
        "keywords": [
            "structure and stability",
            "density functional theory",
            "ion cluster",
            "photoelectron energy speotrum"
        ],
        "authors": [
            {
                "name": "Ma Deming",
                "org": "Science School, Xi'an University of Technology, Xi'an, Shaanxi , China"
            },
            {
                "name": "Shi Wei",
                "org": "Science School, Xi'an University of Technology, Xi'an, Shaanxi , China"
            },
            {
                "name": "Li Enling",
                "org": "Science School, Xi'an University of Technology, Xi'an, Shaanxi , China"
            },
            {
                "name": "Hou Liping",
                "org": "Science School, Xi'an University of Technology, Xi'an, Shaanxi , China"
            },
            {
                "name": "Dai Yuanbin",
                "org": "Science School, Xi'an University of Technology, Xi'an, Shaanxi , China"
            }
        ],
        "venue": "Acta Optica Sinica",
        "year": 2009
    },
    "Q0HfwtZ8": {
        "id": "Q0HfwtZ8",
        "title": "Urinary messenger RNA of the receptor activator of NF-kappaB could be used to differentiate between minimal change disease and membranous nephropathy.",
        "abstract": "Podocyte damage and loss together have an important role in the pathogenesis and progression of glomerulonephritis. Glomerulonephritis patients and healthy controls were enrolled in this study. Biochemical, clinical and experimental procedures included measurement of total urinary protein, renal biopsy and gene expression analysis of the receptor activator of NF-kappaB (RANK). The urinary mRNA levels of RANK were significantly higher in the glomerulonephritis group compared to the controls. The urinary RANK level of glomerular subtypes was correlated significantly with proteinuria. The calculated area of RANK mRNA levels under the curve was 0.61 for minimal change disease (MCD), 0.97 for membranous nephropathy (MN), 0.65 for IgA nephropathy (IgAN), 0.70 for lupus nephritis (LN) and 0.70 for focal segmental glomerulosclerosis (FSGS). The urinary mRNA of RANK might be used to differentiate histologic subtypes of glomerulonephritis, particularly between MCD and MN.",
        "keywords": [
            "Biomarkers",
            "podocytes",
            "receptor activator of NF-kappa B"
        ],
        "authors": [
            {
                "name": "Shuangxin Liu",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Ping Mei",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Pathol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Bin Zhang",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Sijia Li",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Xinling Liang",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Zhiming Ye",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Lixia Xu",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Jianchao Ma",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Zhilian Li",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Li Zhang",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Wenjian Wang",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Liping Wang",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Rizhao Li",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Zhonglin Feng",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Wei Dong",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            },
            {
                "name": "Yiming Tao",
                "org": "Guangdong Gen Hosp, Guangdong Acad Med Sci, Dept Nephrol, Guangzhou 510080, Guangdong, Peoples R China"
            }
        ],
        "venue": "BIOMARKERS",
        "year": 2014
    },
    "jYdNIabq": {
        "id": "jYdNIabq",
        "title": "Electronic assembly with stacked IC's using two or more different connection technologies and methods of manufacture",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "qing a zhou",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2009
    },
    "pRnrGzde": {
        "id": "pRnrGzde",
        "title": "Expressing Service and Query Behavior Using \\pi-Calculus for Matchmaking",
        "abstract": "Service discovery becomes a key to accelerating the evolution of web services as the number of services is expected to increase dramatically. Foregoing work on service discovery is primarily based on the interfaces of services through the use of ontology. Ongoing work targets at service behavior, with not only individual message exchanges being captured, but also constraints between these message exchanges. In this paper, we propose a formal approach to expressing the service and query behavior using 冒-calculus for service matchmaking. The resulting 冒-calculus expressions of services and queries are precise in defining single operations involving message exchanges as well as execution sequence between operations. Based on the formalizations, service matchmaking between a service query and a service description is reasoned through the capability of 冒-calculus. Expressing service behavior using 冒-calculus is expected to be a promising way to realize intelligent service discovery.",
        "keywords": [
            "service query",
            "expressing service",
            "service discovery",
            "query behavior",
            "service matchmaking",
            "calculus expression",
            "service behavior",
            "message exchange",
            "web service",
            "service description",
            "intelligent service discovery",
            "expressing service behavior",
            "message passing",
            "pi calculus",
            "web services"
        ],
        "authors": [
            {
                "name": "Li Kuang",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Ying Li",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Shuiguang Deng",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Zhaohui Wu",
                "org": "Zhejiang University, China"
            }
        ],
        "venue": "Web Intelligence",
        "year": 2006
    },
    "nMVuiUpH": {
        "id": "nMVuiUpH",
        "title": "An efficient THz source with a tuning range of 71.1-2830 /spl mu/m (0.106-4.22 THz) based on frequency mixing in a GaP crystal",
        "abstract": "",
        "keywords": [
            "neodymium",
            "oscillations",
            "gap",
            "cross section"
        ],
        "authors": [
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            },
            {
                "name": "wei shi",
                "org": "lehigh university"
            }
        ],
        "venue": "",
        "year": 2005
    },
    "KaYR1sCq": {
        "id": "KaYR1sCq",
        "title": "Synthesis and caracterization of dithiophene-pyridazine-containing poly(aryleneethynylene) derivatives",
        "abstract": "A novel class of poly(aryleneethynylene) derivatives were synthesized by Pd(PPh3)4/CuI via cross coupling between the large band-gap monomer,1,4-diethynyl-2,5-bis(n-dodecyloxy)benzene (PE),and low band-gap monomer,3,6-bis(2-thienyl)pyridazine(TPD),in the medium of tetrahydrofuran and diisopropylamine. These polymers are soluble in common organic solvents and possess good film-formability due to the decoration of flexible oxyalkyl chains. The UV-Vis absorption,photoluminescent and electrochemical properties of the resulted copolymers are studied here. The quantum efficiency of the copolymers are 51%-61% in THF. Absorption onsets and emission maxima of these polymers are significantly red-shifted along with the increase of TPD's fraction in polymers' backbones. The maximum emissions of copolymers' films peak at 540-551nm.",
        "keywords": [
            "pyridazine",
            "thiophene",
            "poly(aryleneethynylene)"
        ],
        "authors": [
            {
                "name": "QIN Hong-mei",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "HAN Yan",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "LI Wan-li",
                "org": "Key Laboratory for Petroleum and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Materials",
        "year": 2010
    },
    "D2POYD9V": {
        "id": "D2POYD9V",
        "title": "A Review of the Research on Moral Psychological Licensing",
        "abstract": "Moral psychological license may be defined as people's perception that they are permitted to take an action or express a thought without fear of discrediting themselves.We present evidence that good behavior in one domain can license otherwise-discrediting behavior in the same domain or an unrelated domain.Observers are sometimes willing to extend license to actors on the basis of the actors' behavioral history.The potential mechanisms behind licensing are moral credits and moral credentials which can be viewed as two independent routes.When one acts in domains that are relatively unimportant to one's identity or can avoid appearing hypocritical,one's behavioral history will liberate rather than constrain future behaviors.We also discuss remaining questions in the literature and propose avenues for future research,the questions including the relationship between self-licensing and person-licensing,verification fundamental assumptions of moral credits and moral credentials models,the desirable consequences of moral licensing.",
        "keywords": [
            "moral credentials",
            "moral credits",
            "hypocrisy",
            "moral psychological licensing"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2011
    },
    "D1OYmiJM": {
        "id": "D1OYmiJM",
        "title": "Expression of Tissue-type Plasminogen Activator and Plasminogen Activator Inhibitor Type-1 Protein by Western blot in Human Glioma",
        "abstract": "Objective:To study the expression and significance of tissue-type plasminogen activator and plasminogen activator inhibitor type-1 in human glioma,and the analysis of the relationship with malignant biological behavior of human glioma.Methods:tPA and PAI-1 protein expression levels have been detected by ECL-Western blot in surgical samples of 41 patiens with human glioma and 10 samples of normal brain tissue obtained from craniocerebral injury surgery.Results:The expression level of tPA protein in high-grade gliomas was extremely low,but was higher in low-grade gliomas,and showed normal quantities in normal brain tissues.The difference among low-grade gliomas,high-grade gliomas and normal brain tissues was less evident(P>0.05).The expression of tPA protein has no clear relationship with glioma grade(P>0.05).Along with the rise of glioma grade,the PAI-1 protein expression level was also upregulated,but the level of PAI-1 in normal brain tissue was extremely low.There was significant difference among normal brain tissues,low-grade gliomas and high-grade gliomas(P<0.05).The expression of PAI-1 protein was correlated positively with pathological grade of glioma(P<0.05).Conclusion:The high level of PAI-1 protein reflects a malignant biological behavior of human glioma;tPA may be a characteristic of well differentiated tissue.",
        "keywords": [
            "glioma",
            "Western blot",
            "plasminogen activator inhibitor type-1",
            "tissue-type plasminogen activator"
        ],
        "authors": [
            {
                "name": "SU Xing",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Jiangsu"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Jiangsu"
            },
            {
                "name": "CHEN Jian",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Jiangsu"
            }
        ],
        "venue": "Medical Journal of Communications",
        "year": 2011
    },
    "Oxr1V8j2": {
        "id": "Oxr1V8j2",
        "title": "System simulation and implementation of multi-function clock based on AT89S52",
        "abstract": "Basing on single-chip technology principle, using AT89S52 as the core controller, it designs a multifunctional digital clock system through the production of hardware circuits and software programming. Use LCD12864 to display seconds, minutes, hours, count values in the cells and values of temperature and humidity. Finally, it uses Proteus to simulate the design to improve the efficiency of single-chip system, and to avoid the blindness of physical welding.",
        "keywords": [
            "electronic clock",
            "AT89S52",
            "simulation"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Microcomputer Information",
        "year": 2011
    },
    "R6L6dqeM": {
        "id": "R6L6dqeM",
        "title": "Effect of Tianqi Injection on the Micro-inflammation and Cellular Immunity in Patients With Chronic Kidney Disease at the Ⅱ-Ⅳ Stage",
        "abstract": "Objective To investigate the effect of Tianqi injection on the micro-inflammation and cellular immunity in patients with chronic kidney disease(CKD) at the Ⅱ-Ⅳ stage.Methods Seventy-one patients with CKD were randomly divided into treatment group(n=36) and the control group(n=35) according to the method of Doll′s clinical case.The patients in the two groups were treated by protecting kidney,excreting poisonous,reducing blood pressure,correcting metabolic acidosis and anemia.Besides,the patients in the treatment group treated by intravenous Tianqi injection for one month.One month was defined as a course of treatment in the two groups.The changes of interleukin-8(IL-8),interleukin-6(IL-6),tumor necrotizing factor-α(TNF-α),serum total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL),high density lipoprotein(HDL),the numbers of dendritic cell(DC) and the ratio of CD4+ to CD8+ were observed after two courses of treatment.Results Compared with the controls,the level of serum IL-8,IL-6,TNF-α,TC,TG and LDL in the treatment group after treatment decreased significantly,while the level of HDL,the numbers of DC and the ratio of CD4+ to CD8+ increased significantly.There was significant difference between the two groups(P<0.05).Conclusion Tianqi injection can imariolate the micro-inflammatory in the patients with CKD,which was correlated with regulation of lipid metabolism and improvement of cellular immunity.",
        "keywords": [
            "Micro-inflammation",
            "Chronic kidney disease",
            "Cellular immunity",
            "Tianqi injection"
        ],
        "authors": [
            {
                "name": "WU Jin-yu",
                "org": " Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "HUANG Ren-fa",
                "org": " Department of Nephrology,the Affiliated Ruikang Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "HUANG Xue-xia",
                "org": " Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "QIN Zuo-lian",
                "org": " Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            }
        ],
        "venue": "Guangxi Medical Journal",
        "year": 2012
    },
    "jbw9OIHQ": {
        "id": "jbw9OIHQ",
        "title": "Effect of the electrostatic interactions of chromophores on the macroscopic second-order nonlinear optical properties of the polymer films",
        "abstract": "The polyetherketone (PEK-c) guest-host system thin films doped with 3-(1,1-dicyanothenyl)-1-phenyl-4,5-dihydro-1H-pryazole (DCNP) were prepared. Their second-order nonlinear optical (NLO) coefficents χ33 (2) were measured by using Maker fringe method for the polymer films doped with different weight percents of DCNP. Experimental results indicate that the second-order NLO properties of the poled polymer films could decrease with the chromophore loading increasing when the chromophore loading reaches a fairly high level. In this paper, the relationship between the macroscopic second-order NLO coefficient and the chromophore number density was modified under considering the role of the electrostatic interactions of chromophores in the polymer film. According to the modified relationship, the macroscopic second-order NLO coefficient is no longer in direct proportion with the chromophore number density in the polymer film. The effect of the electrostatic interactions of chromophores on second-order NLO properties was discussed. The attenuation of the macroscopic second-order NLO activity can be demonstrated by the role of the chromophore electrostatic interactions at high loading of chromophore in the polymer systems.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Zhiling Xu",
                "org": "Fudan University(Fudan University),Shanghai,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xian Zhao",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qintian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Dong Xü",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Wuli Xuebao/Acta Physica Sinica",
        "year": 2000
    },
    "nufp7m9q": {
        "id": "nufp7m9q",
        "title": "Study of the single-beam reflection technique for measuring the linear electro-optic coefficient of the nonlinear optical polymer films",
        "abstract": "",
        "keywords": [
            "electro-optical coefficient",
            "polymers film",
            "reflection technique",
            "phase shift",
            "nonlinear optics",
            "thin film"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            },
            {
                "name": "Qiwei Pan",
                "org": ""
            },
            {
                "name": "Qingtian Gu",
                "org": ""
            },
            {
                "name": "Xiangwen Wu",
                "org": ""
            },
            {
                "name": "Dong Xu",
                "org": ""
            },
            {
                "name": "Hongzhen Wei",
                "org": ""
            },
            {
                "name": "Jinzhong Yu",
                "org": ""
            }
        ],
        "venue": "Integrated Ferroelectrics",
        "year": 2001
    },
    "2jN0GDJI": {
        "id": "2jN0GDJI",
        "title": "Properties of Paraffin Phase-Change-Material(PCM) Mass Concrete for Temperature Control",
        "abstract": "Phase change material(PCM) can be applied in mass concrete to prevent thermal cracks.The latent heat in phase change material is released or absorbed in a certain temperature to control temperature in mass concrete,so that PCM can be used to control temperature stress in mass concrete and prevent tempera-(ture) cracking in concrete.Temperature distribution was tested in center area of PCM mass concrete for temperature control.Compressive strength and permeability of PCM mass concrete were tested,and microscopic pore structure of PCM mortar was also investigated.The results show that the compressive strength of concretc is reduced by adding PCM,but the anti-permeability of concrete is enhanced.The total porosity of PCM mortar does not change much compared with ordinary mortar,however,the pore(diameter) becomes bigger;the maximum temperature in mass concrete is also decreased by adding PCM;moreover,the rate of temperature increasing process and temperature dropping process are lowered,thus temperature crack formation in mass concrete can be prevented.",
        "keywords": [
            "Mass concrete",
            "Phase change material(PCM)",
            "Temperature crack"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "HOU Jing-peng",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "ZHANG Xiong",
                "org": "Key Laboratory of Advanced Civil Engineering Materials of Ministry of Education,Tongji University,Shanghai ,China"
            }
        ],
        "venue": "Journal of Building Materials",
        "year": 2010
    },
    "gf0tcqdY": {
        "id": "gf0tcqdY",
        "title": "The complete mitochondrial genome of a striped sole Zebrias zebrinus (Pleuronectiformes: Soleidae)",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "xiaoyu kong",
                "org": ""
            },
            {
                "name": "liangmin huang",
                "org": ""
            },
            {
                "name": "xianguang miao",
                "org": ""
            },
            {
                "name": "shuying wang",
                "org": ""
            },
            {
                "name": "jinxia jiang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "zhongming wang",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2013
    },
    "ITcb13Bb": {
        "id": "ITcb13Bb",
        "title": "Research on SOC estimation for LiFePO_4 Li-ion batteries",
        "abstract": "The very broad plateau of LiFePO4 Li-ion batteries and serious polarization on both ends are not conducive to SOC estimation,but SOC value has definite major influence upon cell inconsistency and service life.Based on the existing SOC estimation methods of LiFePO4 Li-ion batteries and the analysis of voltammeter curve correspond-ing to electrochemical characteristics,a reliable and accurate method of △Q/△V under different charging rates and aging stages is presented in detail,and the SOC value is revised by peak △Q during the charging process.The online equaliza-tion of battery packs and control strategies of intelligent battery management system for electric vehicle are validated by the accuracy of SOC estimation.",
        "keywords": [
            "SOC estimation",
            "△Q/△V",
            "LiFePO4",
            "Electric vehicle"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "School of electrical engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Jiang Jiuchun",
                "org": "School of electrical engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Li Suoyu",
                "org": "School of electrical engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "Jia Rongda",
                "org": "School of electrical engineering,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Journal of Electronic Measurement and Instrument",
        "year": 2010
    },
    "098a4Xsx": {
        "id": "098a4Xsx",
        "title": "The Theory and Research on the Intrusive Memory about Traumatic Events",
        "abstract": "Intrusive memory is very common phenomena in the traumatic events,with the character of frequency,uncontrollableness,easy activation,and so on;cognitive process theory and warning signal theory can explain the evolvement of intrusive memory,moreover,its distress,nowness and lack-connection can effectively predict Posttraumatic Stress Disorder;the main influence on the intrusive memory has cognitive evaluation and coping strategies;the frequent intrusion can reduce the quality of people's living,but the interruption of intrusive memory such as imaginal reliving,social support,expressive writing can effectively reduce intrusive memory.",
        "keywords": [
            "warning signal theory",
            "thought suppression",
            "cognitive theory",
            "imaginal reliving",
            "intrusive memory"
        ],
        "authors": [
            {
                "name": "LIU Jie",
                "org": " School of Culture and Social Development Studies,Southwest University,Chongqing,"
            },
            {
                "name": "SHI Wei",
                "org": " School of Culture and Social Development Studies,Southwest University,Chongqing,"
            }
        ],
        "venue": "Journal of Southwest China Normal University(Natural Science Edition)",
        "year": 2008
    },
    "uLO4BiW9": {
        "id": "uLO4BiW9",
        "title": "Marked intra-genomic variation and pseudogenes in the ITS1-5.8S-ITS2 rDNA of Symphurus plagiusa (Pleuronectiformes: Cynoglossidae)",
        "abstract": "The eukaryotic ribosomal DNA (rDNA) cluster consists of multiple copies of three genes (18S, 5.8S, and 28S rDNA) and two internal transcribed spacers (ITS1 and ITS2). In recent years, an increasing number of rDNA sequence polymorphisms have been identified in numerous species. In the present study, we provide 33 complete ITS (ITS1-5.8S-ITS2) sequences from two Symphurus plagiusa individuals. To the best of our knowledge, these sequences are the first detailed information on ITS sequences in Pleuronectiformes. Here, two divergent types (Type A and B) of the ITS1-5.8S-ITS2 rDNA sequence were found, which mainly differ in sequence length, GC content, nucleotide diversity (n), secondary structure and minimum free energy. The ITS1-5.8S-ITS2 rDNA sequence of Type B was speculated to be a putative pseudogene according to pseudogene identification criteria. Cluster analysis showed that sequences from the same type clustered into one group and two major groups were formed. The high degree of ITS1-5.8S-ITS2 sequence polymorphism at the intra-specific level indicated that the S. plagiusa genome has evolved in a non-concerted evolutionary manner. These results not only provide useful data for ribosomal pseudogene identification, but also further contribute to the study of rDNA evolution in teleostean genomes.",
        "keywords": [
            "Blackcheek tonguefish",
            "multigene family",
            "non-concerted evolution",
            "pseudogene",
            "ribosomal RNA gene"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": "Zhejiang Ocean Univ, Natl Engn Lab Marine Germplasm Resources Explorat, Zhoushan 316022, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Prov Key Lab Appl Marine Biol, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510000, Guangdong, Peoples R China"
            },
            {
                "name": "Min Yang",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Prov Key Lab Appl Marine Biol, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510000, Guangdong, Peoples R China"
            },
            {
                "name": "Xiao-Yu Kong",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Prov Key Lab Appl Marine Biol, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510000, Guangdong, Peoples R China"
            }
        ],
        "venue": "ANIMAL BIOLOGY",
        "year": 2018
    },
    "HtDTBZNz": {
        "id": "HtDTBZNz",
        "title": "THz photonic bandgap crystals",
        "abstract": "",
        "keywords": [
            "frequency",
            "photonic crystals",
            "optical waveguides",
            "sun",
            "photonic band gap"
        ],
        "authors": [
            {
                "name": "hongqian sun",
                "org": "lehigh university"
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "yujie j ding",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2003
    },
    "oGZpZ2Vt": {
        "id": "oGZpZ2Vt",
        "title": "Decreasing GSH and increasing ROS in chemosensitivity gliomas with IDH1 mutation.",
        "abstract": "Gliomas are the most malignant and aggressive primary brain tumor in adults. Despite concerted efforts to improve therapies, their prognosis remains very poor. Isocitrate dehydrogenase 1 (IDH1) mutations have been discovered frequently in glioma patients and are strongly correlated with improved survival. However, the effect of IDH1 mutations on the chemosensitivity of gliomas remains unclear. In this study, we generated clonal U87 and U251 glioma cell lines overexpressing the R132H mutant protein (IDH1-R132H). Compared with control cells and cells overexpressing IDH wild type (IDH1-WT), both types of IDH1-R132H cells were more sensitive to temozolomide (TMZ) and cis-diamminedichloroplatinum (CDDP) in a time- and dose-dependent manner. The IDH1-R132H-induced higher chemosensitivity was associated with nicotine adenine disphosphonucleotide (NADPH), glutathione (GSH) depletion, and reactive oxygen species (ROS) generation. Accordingly, this IDH1-R132H-induced growth inhibition was effectively abrogated by GSH in vitro and in vivo. Our study provides direct evidence that the improved survival in patients with IDH1-R132H tumors may partly result from the effects of the IDH1-R132H protein on chemosensitivity. The primary cellular events associated with improved survival are the GSH depletion and increased ROS generation.",
        "keywords": [
            "Gliomas",
            " Isocitrate dehydrogenase 1",
            " Glutathione",
            " Reactive oxygen species",
            " Chemotherapy"
        ],
        "authors": [
            {
                "name": "Jinlong Shi",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu Province, 226001, People's Republic of China."
            },
            {
                "name": "Baolan Sun",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Hao Zuo",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Daming Cui",
                "org": "Department of Neurosurgery, Shanghai Tenth People’s Hospital,Tongji University School of Medicine,Shanghai,China"
            },
            {
                "name": "Lanchun Ni",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,China"
            },
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,China"
            }
        ],
        "venue": "Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine",
        "year": 2015
    },
    "sxmjchlu": {
        "id": "sxmjchlu",
        "title": "Ontology-based transportation information integration",
        "abstract": "The current approach in Intelligent Transportation Systems (ITS) cannot effectively support discovery, negotiation, and invocation of heterogeneous traffic information service at a semantic level. In this paper, we present an ontology-based service oriented information integration architecture that consists of two new aspects. The first aspect is to present our traffic domain ontology model and traffic application ontology model. The second aspect is to utilize our traffic ontology model to integrate and share distributed and heterogeneous traffic information.",
        "keywords": [
            "technology",
            "telematics",
            "intelligent transportation systems"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Ying Li",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Senquan Yan",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Zhaohui Wu",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Kan Zhou",
                "org": "Bank Of China(People's Bank of China),Beijing,China"
            }
        ],
        "venue": "14th World Congress on Intelligent Transport Systems, ITS 2007",
        "year": 2007
    },
    "Ew0Y9hSP": {
        "id": "Ew0Y9hSP",
        "title": "PROGRESS ON WIDELY-TUNABLE MONOCHROMATIC THz SOURCES AND ROOM-TEMPERATURE DETECTIONS OF THz WAVES",
        "abstract": "",
        "keywords": [
            "room temperature",
            "infrared",
            "conversion efficiency",
            "upconversion",
            "absorption spectra"
        ],
        "authors": [
            {
                "name": "yujie j ding",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "Journal of Nonlinear Optical Physics & Materials",
        "year": 2012
    },
    "nT7kG6Ek": {
        "id": "nT7kG6Ek",
        "title": "Micron-thick highly conductive PEDOT films synthesized via self-inhibited polymerization: roles of anions",
        "abstract": "The inhibitor-dependent poly(3,4-ethylenedioxythiophene) (PEDOT) fabrication suffers major problems in the areas of controllability and film thickness. In this work, we found that anions play a key role in both the polymerization and the structure of PEDOT. As a precursor, anions greatly influence the reaction rate and oxidant solubility. In its role as a counter-ion, the anions also affect chain conductance and crystal growth. With these behaviors in mind, a self-inhibited polymerization approach using novel oxidants with appropriate anions was successfully developed to facilitate the fabrication of high quality in situ polymerized PEDOT films and solve the thickness limitation problem. Inhibitor-free heavy oxidative solutions with weakly basic anions enable the spin-coating of thick and homogeneous oxidant layers and also effectively inhibit both the crystallization of the oxidant and H+ formation throughout the polymerization process. PEDOT: dodecylbenzenesulfonate (PEDOT:DBSA) exhibits the highest performance among all candidates due to its appropriate anion basicity and low steric effect. An extremely high doping level of 42.9% is achieved, and an electrical conductivity of similar to 1100 S cm(-1) is successfully maintained for film thicknesses between 310 nm and 1.79 mu m. In addition, the thermoelectric power factor (RT) for pristine films was improved to 77.2 mu W mK(-2) from 69.6 mu W mK(-2) by the dedoping treatment. This study provides a new approach for fabricating high performance PEDOT thick films using anion-based design.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Hongyi Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Tiansong Zhang",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "NPG ASIA MATERIALS",
        "year": 2017
    },
    "8l7wBtQy": {
        "id": "8l7wBtQy",
        "title": "Integrated multimode interference couplers in silicon-on insulator",
        "abstract": "Silicon-on insulator (SOI) is an attractive platform for the fabrication of optoelectronic integrated circuit. Thin cladding layers (<1.0 μm) can be used in SOI waveguide due to the large index step between Si and SiO2, making them compatible with the VLSI technology. Here we demonstrate the fabrication of 1×4 and 2×2 multimode interference (MMI) coupler based on SOI technology. Performances of the devices are analyzed. The minimum excess loss of the devices is about 1.8 dB. The devices show uniform power distribution.",
        "keywords": [
            "silicon",
            "optoelectronics",
            "cladding",
            "integrated circuit",
            "very large scale integration",
            "fabrication",
            "integrated circuits",
            "waveguides",
            "indexation",
            "silicon on insulator"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhongli Liu",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Hongzhi Ma",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Guohua Li",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2000
    },
    "F56crHM1": {
        "id": "F56crHM1",
        "title": "Preventive effect of curcumin on contrast-induced nephropathy in rats",
        "abstract": "Objective To study the effect of curcumin on contrast-induced nephropathy(CIN) in rats. Methods Female Sprague-Dawley rats were randomly divided into three groups:control(C),iopromide-370 (CIN) and iopromide-370+curcumin(CUR).CIN was established by administering indomethacin,followed at 15 and 30 min,respectively,by L-NAME and iopromide-370(8 mL/kg) via caudal vein.Curcumin was administered 5 days prior to injecting of iopromide-370.All rats were killed at 24 hours after the administering of iopromide-370. Renal tubular cell apoptosis was evaluated by TUNEL.Kidney malonaldehyde(MDA) was detected by thiobarbituric acid test reaction(TBA).Results Pretreatment with curcumin significantly decreased tubular necrosis,medullary congestion,tubular apoptosis,kidney MDA,serum creatinine and kidney hypertrophy index of CIN.Conclusion This study demonstrated the protective role of curcumin against contrast-induced nephropathy in rats through its antioxidant effect.",
        "keywords": [
            "Curcumin",
            "Oxidative stress",
            "Contrast-induced nephropathy"
        ],
        "authors": [
            {
                "name": "PENG Yan-qiang",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "CHEN Yong-song",
                "org": ""
            },
            {
                "name": "LIANG Xin-ling",
                "org": ""
            },
            {
                "name": "ZHONG Zhuo-heng",
                "org": ""
            },
            {
                "name": "YAN Chun-ying",
                "org": ""
            },
            {
                "name": "WU Min",
                "org": ""
            },
            {
                "name": "LIN Tan-fa",
                "org": ""
            }
        ],
        "venue": "The Journal of Practical Medicine",
        "year": 2011
    },
    "TZDNek9q": {
        "id": "TZDNek9q",
        "title": "Meta-analysis on Dronedarone in Treatment of Atrial Fibrillation or Atrial Flutter",
        "abstract": "OBJECTIVE:To evaluate the efficacy and safety of dronedarone for atrial fibrillation or atrial flutter.METHODS:The publicly published literatures about the clinical trials on dronedarone for atrial fibrillation or atrial flutter were retrieved from PubMed.The quality analysis of included studies and extraction and cross-check of data were conducted by two reviewers independently using Meta-analysis.Response indexes were tested in tests for heterogeneity and summarized and analyzed using RevMan 5.0.The safety of dronedarone was evaluated.RESULTS:Five RCTs were included.As compared with placebo,dronedarone reduced the hospitalization rate due to cardiovascular events and all-cause mortality(RR=0.76,95%CI=0.72～0.79,P<0.000 01) and ventricular rate during onset of atrial fibrillation or atrial flutter(WMD=-14.60,95%CI=-15.06～-14.14,P<0.000 01).But dronedarone have no impact on recurrence of atrial fibrillation or atrial flutter(RR=0.96,95%CI=0.80～1.16,P=0.68).Dronedarone was well tolerated.CONCLUSION:It is effective and safe to teat atrial fibrillation or atrial flutter with dronedarone.More high-quality and large-scale randomized controlled trials are required for further study and certification.",
        "keywords": [
            "Dronedarone",
            "Atrial flutter",
            "Meta-analysis",
            "Atrial fibrillation"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "SHAO Jiang",
                "org": "Chongqing Three Gorges Central Hospital,Chongqing ,China"
            },
            {
                "name": "PANG Xiao-hua",
                "org": "Chongqing Three Gorges Central Hospital,Chongqing ,China"
            }
        ],
        "venue": "China Pharmacy",
        "year": 2010
    },
    "AzWsAtVj": {
        "id": "AzWsAtVj",
        "title": "Clincal Experience of Professor Shiwei Treating Chronic Renal Failure Based on Overall Analysis of Symptoms and Signs of Spleen and Kidney",
        "abstract": "Objective:The clincal experience of Professor SHI Wei treating chronic renal failure based on the overall analysis of symptoms and signs of spleen and kidney was introduced.Method:In the learning process by following Professor SHI,arranging and inducing the clinical experience,the thought method and summarizing the experience of treating chronic renal failure based on the overall analysis of symptoms and signs of spleen and kidney were important.Results:Before treating chronic kidney failure,Professor SHI divides the right symptoms and signs for the diagnosis and treatment in TCM,which mainly manifests as the deficiency of yang or yin of kidney,the deficiency of qi and yin of spleen and kidney,the cooperate in incoordination between stomach and spleen,the internal accumulation of dampness,turbidity and damp-toxin,blockage of meridians for blood stasis.Conclusion:The effect of Professor Shiwei treating chronic renal failure based on the overall analysis of symptoms and signs of spleen and kidney is remarkable,its clinical experience is worth of discussing and studying.",
        "keywords": [
            "diagnosis and treatment based on the overall analysis of symptoms and signs of spleen and kidney",
            "diagnosis and treatment",
            "chronic renal failure",
            "clincal experience of famous TCM doctor",
            "SHI Wei"
        ],
        "authors": [
            {
                "name": "LIANG Li-li",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "SONG Dan",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "CHEN Jian",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "SHI Wei",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            }
        ],
        "venue": "Journal of Liaoning University of Traditional Chinese Medicine",
        "year": 2012
    },
    "UJz4iB7E": {
        "id": "UJz4iB7E",
        "title": "Correlation between hemorrhage and vessel depth of peptic ulcer",
        "abstract": "Objective To investigate correlation between depth of vessels in the bottom of peptic ulcer and hemorrhage from ulcer,so as to determine a critical point of vessel depth as positive standard of endoscopic Doppler ultrasound.Methods A 16 MHz ultrasonic Doppler transducer was used through the accessory channel of an endoscope,if an acute peptic ulcer was found during gastroscopy,to assess the blood flow in the bottom of ulcer.Cochran Armitage trend test was performed for occurrence rate of hemorrhagic ulcer in different blood vessel depths.We calculated the sensitivity,specificity and accuracy of different blood vessel depths for ulcerative hemorrhage and drew receiver operator characteristic (ROC) curves to determine the standard of blood vessel depth for positive Doppler signal.Results In the 178 patients,66 of the 74 hemorrhagic patients (89.2%) had blood flow signal detected at the bottom of the ulcer,while 72 (69.2%) of the 104 non-hemorrhagic did (P < 0.01).The median values of the detected blood vessel depths of the two groups were 0.5mm and 0.9mm respectively (P < 0.001).The incidence rates of hemorrhagic ulcer in different blood vessel depths were significantly different (P < 0.001).ROC curve analysis showed 0.7mm was the best critical point of blood vessel depth,with sensitivity,specificity and accuracy as 79.7%,83.7% and 82.0% respectively.Conclusion Depth of blood vessel in the bottom of peptic ulcer is correlated with hemorrhage.Blood vessel depth below 0.7mm could be used as the positive standard for endoscopic Doppler ultrasound assessment.Further investigation is needed for its value in predicting rehaemorrhagia.",
        "keywords": [
            "Peptic ulcer",
            "Endoscopic Doppler ultrasound",
            "Positive Doppler signal",
            "Blood vessel"
        ],
        "authors": [
            {
                "name": "SUN Xiao-bin",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "XI Wei-dong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "ZHAO Cong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "CHAO Qi-chang",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "NONG Chun-yan",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "YUAN De-qiang",
                "org": "Department of Gastroenterology,The Third People's Hospital of Chengdu,Chengdu ,China"
            }
        ],
        "venue": "Practical Journal of Clinical Medicine",
        "year": 2010
    },
    "v36Q1wdy": {
        "id": "v36Q1wdy",
        "title": "A Novel Approach to the Study of CaCO3 Precipitation Kinetics on Carbon Steel Pipe",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "nan zhang",
                "org": "rice university"
            },
            {
                "name": "amy t kan",
                "org": "rice university"
            },
            {
                "name": "wei shi",
                "org": "rice university"
            },
            {
                "name": "hamad amer alsaiari",
                "org": "saudi aramco"
            },
            {
                "name": "mason b tomson",
                "org": "rice university"
            }
        ],
        "venue": "open source systems",
        "year": 2012
    },
    "Xfms3RoE": {
        "id": "Xfms3RoE",
        "title": "SYNTHESIS AND ELECTROCHEMICAL PROPERTIES OF CARBON NANOTUBE-POLY[3′,4′-ETHYLENEDIOXY-2,2′:5′,2″TERTHIOPHENE] NANOCOPOSITES",
        "abstract": "in order to investigate electrochemical properties of a novel composite made from poly[3′,4′-ethylenedioxy-2,2′:5′,2″-terthiophene](PTET) and carbon nanotubes(CNT),a derivative of ethylenedioxy-substituted terthiophene was synthesized as the precursors via Stille reaction,and chemical polymerization method was used to prepare PTET-CNT nanocomposites by coating PTET on the surface of the CNT by FeCl_3 as catalysts in dry CHCl_3 at 0～5℃.The composite was characterized by Fourier transform infrared spectroscopy(FTIR),transmission electron microscope(TEM) and scanning electron microscopy(SEM).FTIR spectra indicate that PTET of the composite more easily exists at the α,α′-positions than pure PTET,TEM and SEM images reveal that this composite has a core-shell structure with nanometer scale PTET layers.Electrochemical behavior of the composite electrode was evaluated by cyclic voltammetry(CV),electrochemical impedance spectroscopy(EIS) and galvanostatic charge-discharge tests with a three-electrode system in 0.1 mol/L Et_4NPF_4/acetonitrile(AN) solution.CV curves of the composite electrodes indicate that the composites not only present a large background current,but also a couple of redox peak with potentials of E_(pa)=1.2 V and E_(pc)=-0.2 V(versus Ag/AgCl),respectively.Galvanostatic charge-discharge curves show that the composite possesses higher specific capacitance and performs much better than carbon nanotubes under high current densities.A comparative analysis of original carbon nanotubes electrode was also conducted under similar conditions.At a current density of 3 mA/cm~2,the PTET-CNT nanocomposite electrode exhibits high specific capacitance of 86 F/g,in comparison with a value of 20 F/g for the carbon nanotubes electrode,increased by 3.3 times than carbon nanotubes electrode.And supercapacitors based on the PTET-CNT nanocomposite and carbon nanotubes have an energy density of 2.02 and 0.47 Wh/kg,respectively.",
        "keywords": [
            "4′-ethylenedioxy-2",
            "Poly[3′",
            "Carbon nanotube",
            "Nanocomposite",
            "2′:5′",
            "2″-terthiophene]"
        ],
        "authors": [
            {
                "name": "ZHAO Chunbao",
                "org": "%%#~1 School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi "
            },
            {
                "name": "LEI Yubin",
                "org": "%%#~2 The 1th Hydrological Engineering Geology Team,Bureau of Geology and Mineral Resources in Xinjiang,Urumqi "
            },
            {
                "name": "SHI Wei",
                "org": "%%#~1 School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi "
            }
        ],
        "venue": "Acta Polymerica Sinica",
        "year": 2009
    },
    "CWpSGR2S": {
        "id": "CWpSGR2S",
        "title": "Transient global cerebral ischemia induces up-regulation of MLTKα in hippocampal CA1 neurons.",
        "abstract": "MLTK (mixed-lineage kinase-like mitogen-activated protein triple kinase) is a member of the mitogen-activated protein kinase family and functioned as a mitogen activated kinase kinase kinase. MLTKα, one of the alternatively spliced forms of MLTK, could activate the c-Jun N-terminal kinase pathway, which involved in cellular stress responses and apoptosis. But the role of MLTKα in neural apoptosis was still unclear. Here, we performed a transient global cerebral ischemia model (TGCI) in adult rats and detected the dynamic changes of MLTKα in hippocampal CA1 neurons and brain cortex. We found the MLTKα expression was increased shortly after TGCI and peaked after 8 h. In spatial distribution, MLTKα was widely located in neurons rather than astrocytes and microglia. Moreover, there was a concomitant up-regulation of active caspase-3. Taken together, we hypothesized the up-regulation of MLTKα played an essential role in the apoptosis of hippocampal CA1 neurons.",
        "keywords": [
            "Hippocampal CA1",
            " Neurons",
            " Apoptosis",
            " Transient global cerebral ischemia",
            " MLTKα"
        ],
        "authors": [
            {
                "name": "Xing Su",
                "org": "Department of Neurosurgery, Surgical Research Center, Hospital Affiliated to Nantong University, Xisi Road 20#, Nantong, 226001, Jiangsu, China."
            },
            {
                "name": "Chang-Lai Zhu",
                "org": "Jiangsu Key Laboratory of Neuroregeneration,Nantong,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery, Surgical Research Center,Hospital Affiliated to Nantong University,Nantong,China"
            },
            {
                "name": "Lan-Chun Ni",
                "org": "Department of Neurosurgery, Surgical Research Center,Hospital Affiliated to Nantong University,Nantong,China"
            },
            {
                "name": "Jian-Hong Shen",
                "org": "Department of Neurosurgery, Surgical Research Center,Hospital Affiliated to Nantong University,Nantong,China"
            },
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery, Surgical Research Center,Hospital Affiliated to Nantong University,Nantong,China"
            }
        ],
        "venue": "Journal of molecular histology",
        "year": 2012
    },
    "gex4EggE": {
        "id": "gex4EggE",
        "title": "Research on Influencing Factors and Reducing Methods of the Power Loss by Ground Wire in 750 kV Power System",
        "abstract": "With the increasing of voltage grade of power system,the power loss at ground wire becomes more and more remarkable.Therefore,research on its reduction has great significance for economy and energy saving.The cause of the electric energy loss has been analyzed.The power loss reduction mall occasions and the validity to ground line sectionalization was calculated using EMTP program.It is determined that application of subsectional insulation on 750 kV transmission line can considerably reduce the inductive current on ground wire,reducing the power losses by 99% than that of direct grounding at two ends.Effort shall be made to keep balance of loads between three phases as the unbalanced load leads to more power losses.Proper adjusting section distance can reduce the power losses at ground wire to minimum.",
        "keywords": [
            "power loss",
            "overhead ground wire",
            "EMTP",
            "inductive voltage"
        ],
        "authors": [
            {
                "name": "ZHANG Ya-ting",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "GAO Bo",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering,Xi′an Jiaotong University,Xi′an ,China"
            }
        ],
        "venue": "Insulators and Surge Arresters",
        "year": 2008
    },
    "Np1oh9UP": {
        "id": "Np1oh9UP",
        "title": "Refractive index dispersion measurement on nonlinear optical polymer using V-prism refractometer",
        "abstract": "By using V-prism refractometer, the refractive indices of a polyetherketone (PEK-c) guest–host polymer system were measured with the polymer in solutions. The Lorenz–Lorentz local field formalism was used in the calculation of the refractive indices of the polymers from the measured indices of the polymer solutions and the pure solvent by using V-prism refractometer. The refractive index dispersions of the polymers were obtained by fitting the measured indices of the polymers to Sellmeyer equation. The method allows for an accuracy in index of 0.7% in the determination of the polymer indices. In addition, a large difference between the indices of the polymer and the solvent, and a higher polymer volume fraction in the measured polymer solution are favorable for a high accuracy.",
        "keywords": [
            "nonlinear optical polymer",
            "refractive index",
            "refractive index dispersion",
            "volume fraction",
            "nonlinear optics",
            "local field"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan Shandong 250100, People's Republic of China"
            },
            {
                "name": "Xin Yin",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan Shandong 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan Shandong 250100, People's Republic of China"
            },
            {
                "name": "Xun Sun",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan Shandong 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan Shandong 250100, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Optics and Lasers in Engineering",
        "year": 1999
    },
    "spIeSMp6": {
        "id": "spIeSMp6",
        "title": "Occurrence and Potential Causes of Androgenic Activities in Source and Drinking Water in China",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "hongxia yu",
                "org": ""
            },
            {
                "name": "john p giesy",
                "org": ""
            },
            {
                "name": "sulan chen",
                "org": ""
            },
            {
                "name": "guanjiu hu",
                "org": ""
            },
            {
                "name": "jianfang feng",
                "org": ""
            },
            {
                "name": "xiaowei zhang",
                "org": ""
            },
            {
                "name": "si wei",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "xinxin hu",
                "org": ""
            }
        ],
        "venue": "Environmental Science & Technology",
        "year": 2013
    },
    "S12X5WVc": {
        "id": "S12X5WVc",
        "title": "Influences of the gain and absorption spoilage effect of medium on Y-squeezing of 2MQES light-field",
        "abstract": "The 2MQES(or Two state-superposition multimode quantum entanglement state) light-field |Ψ(2)MF(αj)〉q along Z direction spreading in the gain medium and absorption medium is constructed.The multimode squeezed state theory is used to research the effect of the generalized nonlinear equal-power N-power Y-squeezing of 2MQES light-field,the influences of the gain and absorption spoilage effect of medium upon the generalized nonlinear equal-power N-power Y-squeezing of 2MQES light-field are analyzed in detail.It is found that,under the condition of the gain parameter.αj>0,both the generalized electric-field component and the generalized magnetic-field component of state |Ψ(2)MF(αj)〉q can present a N-power Y-squeezing effect,and when αj is increase,both the squeezed amplitude and the squeezed intensity of the N-power Y-squeezing will diminish.Under the condition of the absorption spoilage coefficient αj<0,both the generalized electric-field component and the generalized magnetic-field component of state |Ψ(2)MF(αj)〉q can present a N-power Y-squeezing effect,while |αj| is increase,both the squeezed amplitude and the squeezed intensity of the N-power Y-squeezing will increase.When the absorption effect is increasingly strong,both the squeezed amplitude and the squeezed intensity are increasingly big.It is shows that absorption medium is advantageous to squeezing of multimode quantum superposition state light-field.",
        "keywords": [
            "N-power Y-squeezing",
            "2MQES light-field",
            "Gain medium",
            "quantum optics",
            "absorption medium"
        ],
        "authors": [
            {
                "name": "XUE Hong",
                "org": " College of Science,Xi′an University of Technology,Xi′an ,Shaanxi,China; Department of Physics,Weinan Teachers University,Weinan ,Shaanxi,China"
            },
            {
                "name": "SHI Wei",
                "org": " College of Science,Xi′an University of Technology,Xi′an ,Shaanxi,China"
            },
            {
                "name": "LI Wang",
                "org": " Department of Physics,Weinan Teachers University,Weinan ,Shaanxi,China"
            }
        ],
        "venue": "Journal of Shaanxi Normal University(Natural Science Edition)",
        "year": 2008
    },
    "ZYLBUkPX": {
        "id": "ZYLBUkPX",
        "title": "Photoconductive Characteristics of Exciton Effect upon GaAs Photoconductive Switch",
        "abstract": "Starting from the effect of GaAs Photoconductive Semiconductor Switch(PCSS) exciton and Photo-Activated Charge Domain(PACD) theory,this paper studies photoconductive behaviors of GaAs photoconductive switch exciton effect in the case of strong electric field excitation.The interaction of PACD and exciton effect and exciton formation,transmission and free electrons and holes formed in the process of dissociation can provide the necessary conditions for exciton activated photoconduction.The major factors affecting exciton effect photoconductive behaviors are: exciton energy absorption,bound exciton and PACD induced band gap renormalization,multi-phonon transition,bound exciton split and drift along dislocation stress.In the case of coupling actions by the above factors,the photoconduction of GaAs photoconductive switch exciton effect appears to have a certain oscillation behaviors.",
        "keywords": [
            "photoconductive behaviors",
            "GaAs Photoconductive Semiconductor Switch(PCSS)",
            "exciton effect",
            "Photo-Activated Charge Domain(PACD)"
        ],
        "authors": [
            {
                "name": "MA Xiangrong",
                "org": "Faculty of Science,Xi' an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Science,Xi' an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2011
    },
    "StgaAQcf": {
        "id": "StgaAQcf",
        "title": "The Design of High Resolution Time to Digit Converter Based on FPGA",
        "abstract": "The paper introduces a new design method of Time-to-Digital Converter with high precision, which invokes the PLL and Ring Shift Register in the chip. The circuit applying the design method has been implemented in FPGA/CPLD (Field Programmable Gate Array or Complex Programmable Logic Device) ,and it could be used as the functional circuit dependently or implanted into other SOC (System on Chip) designs conveniently. The precision with 3.3 nanoseconds can be achieved in Stratix and Cyclone series chip produced by Altera. Timing simulation and testing data indicate the method is right and feasible.",
        "keywords": [
            "PLL",
            "Ring Shift Register",
            "Time to Digit Conversion",
            "FPGA"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "HUANG Chuan-jin",
                "org": ""
            },
            {
                "name": "ZHEN Jing-ran",
                "org": ""
            }
        ],
        "venue": "Microcomputer Information",
        "year": 2009
    },
    "eN1h3rdV": {
        "id": "eN1h3rdV",
        "title": "NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice: NFAT inhibitor ameliorates podocyte injury",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "ruizhao li",
                "org": ""
            },
            {
                "name": "li zhang",
                "org": ""
            },
            {
                "name": "xiaofan tan",
                "org": ""
            },
            {
                "name": "zhuo li",
                "org": ""
            },
            {
                "name": "jianchao ma",
                "org": ""
            },
            {
                "name": "yuxiong lai",
                "org": ""
            },
            {
                "name": "wenjian wang",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "yuanhan chen",
                "org": ""
            },
            {
                "name": "chunping yu",
                "org": ""
            },
            {
                "name": "zhiming ye",
                "org": ""
            },
            {
                "name": "shuangxin liu",
                "org": ""
            },
            {
                "name": "xinling liang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "British Journal of Pharmacology",
        "year": 2013
    },
    "m89eiuol": {
        "id": "m89eiuol",
        "title": "New model for calculating the shielding failure trip-out rate of transmission line",
        "abstract": "To evaluate the shielding failure trip-out rate of the transmission lines accurately, a new model combining electromagnetic transient program (EMTP) simulation with Monte Carlo method is presented, where all random factors are taken into account and the higher accuracy for electromagnetic transient analysis of EMTP is kept. The simulated result shows that the relative error between the calculated result and the on site value gets within 10% to describe the trip-out more actually.",
        "keywords": [
            "Electromagnetic transient program",
            "Monte Carlo method",
            "Regular method",
            "Shielding failure trip-out rate"
        ],
        "authors": [
            {
                "name": "Lei Jia",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Guihong Zhang",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Liang Shu",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Dingjun Wen",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 2007
    },
    "BSQWX43s": {
        "id": "BSQWX43s",
        "title": "Pulmonary hypertension: epidemiology in different CKD stages and its association with cardiovascular morbidity.",
        "abstract": "Pulmonary hypertension (PH) was recently recognized as a common complication of end-stage renal disease (ESRD) that causes an increased risk of mortality. Epidemiological data for this disorder in earlier stages of chronic kidney disease (CKD) and its association with cardiovascular (CV) morbidity are scarce.We retrospectively analyzed 2,351 Chinese CKD patients with complete clinical records and echocardiography data between Jan 2008 and May 2012. The patients were divided into the following 6 groups: CKD Stages 1-4; Stage 5 for those not on or initiated on hemodialysis for <3 months; and Stage 5D for the patients undergoing hemodialysis for ≥3 months. The prevalence of PH and CV morbidity was investigated, and their association was evaluated with a logistic regression model.PH was detected in 426 patients (18.1%). Mild, moderate and severe PH was diagnosed in 12.1%, 4.9% and 1.1% of the patients, respectively. Severe PH was detected in CKD Stages 5 and 5D. CV morbidity was found in 645 patients (27.4%). Compared with the non-PH group, the PH group had a higher risk for cardiac disease but not for cerebrovascular disease risk. PH severity was associated with cardiac morbidity risk [odds ratio (95% CI) for mild PH: 1.79 (1.30-2.47); moderate PH: 2.75 (1.73-4.37); severe PH: 3.90 (1.46-10.42)].Our study showed for the first time the epidemiology profile of PH across the spectrum of CKD. Mild-to-moderate PH occurs with more frequency in advanced CKD, and severe PH is scarce in non-ESRD CKD. PH in CKD is associated with cardiac but not cerebrovascular disease, with increasing cardiac morbidity seen with increasing PH severity. Evidence from prospective studies addressing PH in this population is needed to predict cardiac events.",
        "keywords": [
            "biomedical research",
            "bioinformatics"
        ],
        "authors": [
            {
                "name": "Zhilian Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Shuangxin Liu",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Zhiming Ye",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Yuanhan Chen",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Wenjian Wang",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Ruizhao Li",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Lixia Xu",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Zhonglin Feng",
                "org": "Southern Medical University, Guangzhou, China."
            },
            {
                "name": "Wei Shi",
                "org": "Southern Medical University, Guangzhou, China."
            }
        ],
        "venue": "PloS one",
        "year": 2014
    },
    "2GGhuRDg": {
        "id": "2GGhuRDg",
        "title": "Application of Mathematical Tool in the Physical Problems",
        "abstract": "Master and application of mathematics is an effective tool for solving physics problems and exploring physical thinking.In this paper,the problems of mathematical tool using in physics are discussed;the application of mathematical tool in college physics teaching is analyzed with some examples and the attentions which should pay in the application of mathematical tools are pointed out.",
        "keywords": [
            "college physics",
            "teaching research",
            "mathematical tool"
        ],
        "authors": [
            {
                "name": "XIE Guang-yong",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Applied Physics,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Gansu Lianhe University(Natural Science Edition)",
        "year": 2008
    },
    "IlsuqD71": {
        "id": "IlsuqD71",
        "title": "Exploring Semantic Technologies in Service Matchmakin",
        "abstract": "Internet, to locate target services in an accurate and efficient way becomes increasingly difficult. At present, semantic web service is regarded as the most promising approach to address the challenge. In this paper, an ontology service description language and a query language, OSDL and OSQL are proposed respectively, and then a service matchmaking algorithm based on interface semantics is proposed. The problem of service matchmaking can be attributed to the similarity between the semantic pair, and the similarity is the quantization of their relationship, which is discovered through reasoning on ontology. Unlike the existing semantics-based service matchmaking algorithms, which focus on the relationships among the successors and ancestors of ontology classes, the proposed one also pays attention to the comparability among classes and their property classes. The experiment data indicate that it is worthwhile to take the point into consideration to receive a higher recall and precision.",
        "keywords": [
            "query language",
            "target service",
            "ontology class",
            "ontology service description language",
            "semantic pair",
            "service matchmaking",
            "semantic web service",
            "existing semantics-based service matchmaking",
            "service matchmaking algorithm",
            "service matchmakin",
            "exploring semantic technologies",
            "experiment data",
            "formal specification",
            "query languages",
            "internet"
        ],
        "authors": [
            {
                "name": "li kuang",
                "org": "zhejiang university"
            },
            {
                "name": "jian wu",
                "org": "zhejiang university"
            },
            {
                "name": "shuiguang deng",
                "org": "zhejiang university"
            },
            {
                "name": "ying li",
                "org": "zhejiang university"
            },
            {
                "name": "wei shi",
                "org": "zhejiang university"
            },
            {
                "name": "zhaohui wu",
                "org": "zhejiang university"
            }
        ],
        "venue": "ECOWS",
        "year": 2005
    },
    "Ngjxd3bt": {
        "id": "Ngjxd3bt",
        "title": "Electro-optical Properties and Temporal Stability of the Guest-Host DCNP/PEK-c Polymer Thin Film",
        "abstract": "",
        "keywords": [
            "thin film"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Chang-Shui Fang",
                "org": ""
            },
            {
                "name": "Qi-Wei Pan",
                "org": ""
            },
            {
                "name": "Xun Sun",
                "org": ""
            },
            {
                "name": "Qing-Tian Gu",
                "org": ""
            },
            {
                "name": "Dong Xu",
                "org": ""
            },
            {
                "name": "Hong-Zhen Wei",
                "org": ""
            },
            {
                "name": "Jin-Zhong Yu",
                "org": ""
            }
        ],
        "venue": "Chinese Physics Letters",
        "year": 2000
    },
    "MOey8Jpy": {
        "id": "MOey8Jpy",
        "title": "pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications.",
        "abstract": "Subcellular organelle-specific reagents for simultaneous tumor targeting, imaging, and treatment are of enormous interest in cancer therapy. Herein, we present a mitochondria targeting micelle (PEG-AIE-TPP) by conjugating a triphenylphosphonium (TPP) with a fluorogen which can undergo aggregation-induced emission (AIE). At first, the in vitro and in vivo properties of the PEG-AIE-TPP micelle were characterized in detail. It was found that the micelle was reasonably stable at physiological pH and highly sensitive to mildly acidic pH stimuli. Importantly, this micelle could selectively localize and accumulate in the mitochondria, thus generating an aggregation-induced emission (AIE) effect as confirmed by the green fluorescence. Additionally, the micelle exhibited selective cytotoxicity to cancer cells and negligible toxicity to normal cells in vitro. The in vivo imaging and ex vivo imaging results showed that the accumulation tendency of the micelle at the tumor region was obvious. We also further proved the biocompatible, tumor targeting ability and antitumor activity of the PEG-AIE-TPP micelle in MCF-7 tumor-bearing mice. Accordingly, this mitochondria-targeted therapeutic micelle with good stability, biocompatibility, and tumor-targeting and antitumor activity provides a potentially unique tumor-targeted system for cancer therapy.",
        "keywords": "",
        "authors": [
            {
                "name": "Jieming Li",
                "org": "Chongqing Med Univ, Sch Pharm, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China"
            },
            {
                "name": "Yan Liu",
                "org": "Chongqing Med Univ, Sch Pharm, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China"
            },
            {
                "name": "Huilan Li",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Xinzhou Bi",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Qianqian Qiu",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Bo Zhang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenlong Huang",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOMATERIALS SCIENCE",
        "year": 2018
    },
    "7vY1s6z4": {
        "id": "7vY1s6z4",
        "title": "China collaborative study on dialysis: a multi-centers cohort study on cardiovascular diseases in patients on maintenance dialysis.",
        "abstract": "Cardiovascular disease (CVD) is the main cause of death in patients on chronic dialysis. The question whether dialysis modality impacts cardiovascular risk remains to be addressed. China Collaborative Study on Dialysis, a multi-centers cohort study, was performed to evaluate cardiovascular morbidity during maintenance hemodialysis (HD) and peritoneal dialysis (PD).The cohort consisted of chronic dialysis patients from the database of 9 of the largest dialysis facilities around China. The inclusion period was between January 1, 2005, and December 1, 2010. Cardiovascular morbidity was defined as the presence of clinically diagnosed ischemic heart disease, heart failure, peripheral vascular disease, and/or stroke. The patients who had cardiovascular morbidity before initiation of dialysis were excluded. Data collection was based on review of medical record.A total of 2,388 adult patients (1,775 on HD and 613 on PD) were enrolled. Cardiovascular morbidity affected 57% patients and was comparable between HD and PD patients. However, clinically diagnosed ischemic heart disease and stroke was more prevalent in PD than HD patients. When the patients were stratified by age or dialysis vintage, the cardiovascular morbidity was significantly higher in PD than HD among those aged 50 years or older, or those receiving dialysis over 36 months. Multivariate analysis revealed that the risk factors for cardiovascular morbidity had different pattern in PD and HD patients. Hyperglycemia was the strongest risk factor for cardiovascular morbidity in PD, but not in HD patients. Hypertriglyceridemia and hypoalbuminemia were independently associated with CVD only in PD patients.Cardiovascular morbidity during chronic dialysis was more prevalent in PD than HD patients among those with old age and long-term dialysis. Metabolic disturbance-related risk factors were independently associated with CVD only in PD patients. Better understanding the impact of dialysis modality on CVD would be an important step for prevention and treatment.",
        "keywords": [
            "nephrology",
            "survival analysis",
            "incidence",
            "china",
            "cohort studies",
            "risk factors",
            "internal medicine"
        ],
        "authors": [
            {
                "name": "Fanfan Hou",
                "org": "Division of Nephrology, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, China. ffhouguangzhou@163.com"
            },
            {
                "name": "Jianping Jiang",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Jianghua Chen",
                "org": "Division of Nephrology,The First Affiliated Hospital, Medical College of Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Xueqing Yu",
                "org": "Division of Nephrology,The First Affiliated Hospital, Sun Yat-Sen University,Guangzhou,China"
            },
            {
                "name": "Qiugen Zhou",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Pingyan Chen",
                "org": "Department of Biostatistics,Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Changlin Mei",
                "org": "Division of Nephrology,Changzheng Hospital, Secondary Military Medical University,Shanghai,China"
            },
            {
                "name": "Fei Xiong",
                "org": "Division of Nephrology,The First People’s Hospital,Wuhan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangzhou,China"
            },
            {
                "name": "Wei Zhou",
                "org": "Division of Nephrology,The 309th Hospital of People’s Liberation Army,Beijing,China"
            },
            {
                "name": "Xusheng Liu",
                "org": "Division of Nephrology,Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou,China"
            },
            {
                "name": "Shiren Sun",
                "org": "Division of Nephrology,Xijing Hospital, Fourth Military Medical University,Xi’an,China"
            },
            {
                "name": "Di Xie",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Jun Liu",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Ping Zhang",
                "org": "Division of Nephrology,The First Affiliated Hospital, Medical College of Zhejiang University,Hangzhou,China"
            },
            {
                "name": "Xiao Yang",
                "org": "Division of Nephrology,The First Affiliated Hospital, Sun Yat-Sen University,Guangzhou,China"
            },
            {
                "name": "Yixiang Zhang",
                "org": "Division of Nephrology,Changzheng Hospital, Secondary Military Medical University,Shanghai,China"
            },
            {
                "name": "Yanmin Zhang",
                "org": "Division of Nephrology,The First People’s Hospital,Wuhan,China"
            },
            {
                "name": "Xinling Liang",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangzhou,China"
            },
            {
                "name": "Zhimin Zhang",
                "org": "Division of Nephrology,The 309th Hospital of People’s Liberation Army,Beijing,China"
            },
            {
                "name": "Qizhan Lin",
                "org": "Division of Nephrology,Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou,China"
            },
            {
                "name": "Yan Yu",
                "org": "Division of Nephrology,Xijing Hospital, Fourth Military Medical University,Xi’an,China"
            },
            {
                "name": "Shengjie Wu",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            },
            {
                "name": "Xin Xu",
                "org": "Division of Nephrology,Nanfang Hospital, Southern Medical University,Guangzhou,China"
            }
        ],
        "venue": "BMC nephrology",
        "year": 2012
    },
    "35LpOVhO": {
        "id": "35LpOVhO",
        "title": "Reproductive biology and variation of nuclear ribosomal ITS and ETS sequences in the Calligonum mongolicum complex (Polygonaceae)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Jun Wen",
                "org": ""
            },
            {
                "name": "Yanfeng Zhao",
                "org": ""
            },
            {
                "name": "Gabriel Johnson",
                "org": ""
            },
            {
                "name": "Borong Pan",
                "org": ""
            }
        ],
        "venue": "PhytoKeys",
        "year": 2017
    },
    "ntxX4nkh": {
        "id": "ntxX4nkh",
        "title": "Investigation of the linear electro-optic effect for the guest–host polymer DR13/PEK-c thin films",
        "abstract": "The polyetherketone (PEK-c) guest–host polymer thin films doped with disperse red 13 were prepared by spin-coating method. The corona poling condition was optimized by the poling profiles. The polymer films were poled by corona-onset poling at elevated temperature, and the corona poling setup includes a grid voltage making the surface-charge distribution uniform. The linear electro-optic coefficients of the poled polymer films have been determined at λ=632.8 nm by using a new simple interferometric technique, which is based on compensating the change of the optical length due to the electro-optic effect of the poled polymer film by the anti-piezoelectric effect of a quartz crystal.",
        "keywords": [
            "42.65",
            "78.20j",
            "61.40k",
            "polymer thin film",
            "poling",
            "electro-optic coefficient",
            "thin film"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Xin Yin",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qingtian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hongzhen Wei",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Optics and Lasers in Engineering",
        "year": 2001
    },
    "gKatdhvO": {
        "id": "gKatdhvO",
        "title": "Compare of Scattering Mechanisms in SI GaAs Photoconductive Switch",
        "abstract": "The general expression formulas of scattering rate and the scattering ending of main scattering mechanisms in the SI GaAs photoconductive switch were summarized and compared, in terms of the quantum mechanics theory, the results of situation and analysis were provided.",
        "keywords": [
            "scattering rate",
            "scattering mechanism",
            "Monte Carlo method"
        ],
        "authors": [
            {
                "name": "HOU Jun-yan",
                "org": " Science Institute, Air Force Engineering University, Xi' an , China"
            },
            {
                "name": "DAI Hui-ying",
                "org": " Science Institute, Air Force Engineering University, Xi' an , China; Department of Applied Physics, Xi' an University of Technology, Xi' an , China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Applied Physics, Xi' an University of Technology, Xi' an , China"
            },
            {
                "name": "DONG Qiu-Xia",
                "org": " Science Institute, Air Force Engineering University, Xi' an , China"
            }
        ],
        "venue": "Semiconductor Technology",
        "year": 2006
    },
    "FMYW3yNK": {
        "id": "FMYW3yNK",
        "title": "The Design and Implementation of DPA-Resistant Standard Cells",
        "abstract": "A methodology to design and characterize a DPA-resistant standard cell library is introduced in this paper,and then the designed standard cells are used to implement an S-box of DES.The experimental results demonstrate that the DPA-resistant standard cell library can counteract DPA attacks effectively.",
        "keywords": [
            "Sense amplifier based logic(SABL)",
            "Differential power analysis(DPA)",
            "Standard cell",
            "Design flow"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "DAI Kui",
                "org": "School of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "TONG Yuan-man",
                "org": "School of Computer,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "GONG Rui",
                "org": "School of Computer,National University of Defense Technology,Changsha ,China"
            }
        ],
        "venue": "Microelectronics & Computer",
        "year": 2007
    },
    "jeGzjLoZ": {
        "id": "jeGzjLoZ",
        "title": "Design, synthesis and biological evaluation of novel peptides as potential agents with anti-tumor and multidrug resistance-reversing activities.",
        "abstract": "Tumor chemotherapy is an important mean in the clinical treatment of metastatic cancer,but low selectivity and drug resistance restrict its clinical application. BP100 is a multifunctional membrane-active peptide with high antimicrobial activity. We selected BP100 as a lead peptide, designed and synthesized a series of BP100 analogs through solid-phase synthesis. Amongst them, peptides with the Tyr10 residue substituted by leucine and histidine showed the highest anti-cancer activity. Further experiments revealed that BP100 and its analogs could disrupt the cell membrane and trigger the cytochrome C release into cytoplasm, which ultimately resulted in apoptosis. Meanwhile, BP100 and its analogs also exhibited effective anti-tumor activity against multidrug-resistant cells, showing multidrug resistance-reversing effects. In conclusion, these peptides might be promising candidates for cancer therapy.",
        "keywords": [
            "Anti-cancer",
            "Antimicrobial peptides",
            "Membrane-disruption",
            "Multidrug resistance-reversing effects"
        ],
        "authors": [
            {
                "name": "Bo Zhang",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Wei Shi",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Jieming Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Chen Liao",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Mingxue Li",
                "org": "Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, People's Republic of China."
            },
            {
                "name": "Wenlong Huang",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang,, Nanjing, 210009, People's Republic of China. ydhuangwenlong@126.com."
            },
            {
                "name": "Hai Qian",
                "org": "Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang,, Nanjing, 210009, People's Republic of China. qianhai24@163.com."
            }
        ],
        "venue": "Amino acids",
        "year": 2017
    },
    "njSP73d4": {
        "id": "njSP73d4",
        "title": "Kinetic turbidimetric limulus assay of bacterial endotoxin in the replacement solution of on-line hemodiafiltration]",
        "abstract": "To determine bacterial endotoxin in the replacement solution of on-line hemodiafiltration (on-line HDF) using kinetic turbidimetric limulus test.Validation test was performed with the replacement solution of on-line HDF in which quantified standard endotoxin was added. The recovery rates of endotoxin from the replacement solution and its dilutions at 1/5, 1/10, and 1/20 were 58.17%, 106.7%, 99.00% and 98.79%, respectively, suggesting that the optimal dilution was at 1/10. Standard endotoxin was added into the replacement solution of on-line HDF of 3 batches (040408, 040511,040527), and the recovery rates in their dilution at 1/10 were 76.32%, 99.00% and 96.24%, respectively. The standard endotoxin in the working curve was 1.00, 0.125, and 0.0156 Eu/ml (endotoxin unit/ml), and the dilution at 1/10 of the replacement solution is effective to eliminate the interference in limulus test.Kinetic turbidimetric limulus test provide a means to detect endotoxin in the replacement solution of on-line HDF.",
        "keywords": [
            "on-line hemodiafiltration",
            "replacement solution",
            "kinetic turbidimetric limulus test",
            "inhibition enhancement",
            "bacterial endotoxin"
        ],
        "authors": [
            {
                "name": "Hai-yan Lao",
                "org": ""
            },
            {
                "name": "Qiu-xiao Lin",
                "org": ""
            },
            {
                "name": "Min Yang",
                "org": ""
            },
            {
                "name": "Xin-ling Liang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Hui Li",
                "org": ""
            },
            {
                "name": "Ju-jin Feng",
                "org": ""
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2006
    },
    "EKHJigS1": {
        "id": "EKHJigS1",
        "title": "Analysis of the Long-run Equilibrium Relationship between Scientific Investments and the Economy Development in Northern Anhui Province",
        "abstract": "This study dealt with the relationship between scientific investments and the economy development in Northern Anhui Province.According to the analysis of VECM(Vector Error Correction Model),we found it was obvious that scientific investments booted largely the economy development of Northern Anhui Province,and the coefficient of elasticity was 0.4022 which meant the regional GDP would go up at the rate of 0.4022% with 1% increase of scientific investment.The result also showed that both the short-and long-run equilibriums shaded the regional GDP greatly and the coefficient of error correction term was-1.9922.The result suggested that scientific investments played key roles in the economy development of Northern Anhui Province.",
        "keywords": [
            "Economy Development",
            "Northern Anhui Province",
            "Scientific Investment"
        ],
        "authors": [
            {
                "name": "Zhang Ke-rong",
                "org": "School of Economics and Business Administration,Fuyang,Anhui ,China"
            },
            {
                "name": "Liu Wu-yi",
                "org": "Research Department of Fuyang Normal University,Fuyang,Anhui ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Research Department of Fuyang Normal University,Fuyang,Anhui ,China"
            },
            {
                "name": "Chen De-yu",
                "org": "Research Department of Fuyang Normal University,Fuyang,Anhui ,China"
            }
        ],
        "venue": "Journal of Tongren University",
        "year": 2012
    },
    "AUgwpO45": {
        "id": "AUgwpO45",
        "title": "A Review of Multivariate Integrative Meta-Analysis",
        "abstract": "In traditional meta-analysis,only a single effect size estimate can be produced in each study to make each effect size estimate be independent from each other.If there are multiple effect size estimates in a single study,multivariate meta-analysis technique is needed to deal with the data.Multivariate meta-analysis includes multivariate linear modeling and multivariate integrative method,in which multivariate integrative method is one of the widest used approaches.Multivariate integrative method can solve the problem of multiple dependent effect sizes effectively and can also do the statistical analysis by fixed effects models and mixed effects models.However,some problems still exist in the appliance of multivariate integrative method,such as the development of the statistical software,the stability of the significance of homogeneity Q test and the feasibility of homogeneity test of heterogeneous synthetic effect sizes.",
        "keywords": [
            "multivariate meta-analysis",
            "effect size",
            "synthetic effect size",
            "dependence",
            "multivariate integrative method"
        ],
        "authors": [
            {
                "name": "YE Zi-Jing",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing,,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing,,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2010
    },
    "aQ4zRYqV": {
        "id": "aQ4zRYqV",
        "title": "Cenozoic extensional stress evolution in North China",
        "abstract": "Since the beginning of the Cenozoic, north China has been fragmented by intensive intracontinental rifting and extensional tectonics, which resulted in the formation of two extensional domains: the graben systems around the Ordos block in the west and North China Plain in the east. How to link this Cenozoic extensional tectonics to plate kinematics has long been an issue of debate. This paper presents updated results of fault slip data sets collected in different zones in north China and addresses the changes in the direction of extensional stresses over the Cenozoic. A chronology of three successive extensions has been established and provides evidence for constraining the timing and location of either subduction-induced back-arc tectonics along the western Pacific or collision-related extrusion tectonics in Tibet. The oldest NW–SE trending extension occurred concomitantly with the early Tertiary rifting phase, which was initiated in a back-arc setting associated with westward subduction of the Pacific plate under the Asia continent. North China had been subjected, during the Miocene, to regional subsidence with widespread basalt flow, and the direction of extension changed to NE–SW to NNE–SSW, consistent with the spreading direction of the Japan Sea. The dynamic origin of this extension is poorly understood. Since the latest Miocene or earliest Pliocene, north China has been dominated by NW–SE extension resulting in the formation and development of the elongate graben systems around the rigid Ordos block. This extensional phase is accompanied by counterclockwise rotation of blocks such as Ordos, Taihangshan Massif etc., which are bounded to south by the left-lateral strike-slip Qinling fault system. The overall Pliocene-Quaternary deformation in north China accommodates an ESE-ward extrusion of the south China block relative to the Gobi-Mongolia plateau, as the consequence of late-stage India–Eurasia convergence.",
        "keywords": [],
        "authors": [
            {
                "name": "Zhang Yueqiao",
                "org": ""
            },
            {
                "name": "Ma Yinsheng",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, 11, Minzu Daxue Nanlu, Haidian District, Beijing 100081, China"
            },
            {
                "name": "Yang Nong",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, 11, Minzu Daxue Nanlu, Haidian District, Beijing 100081, China"
            },
            {
                "name": "Shi Wei",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, 11, Minzu Daxue Nanlu, Haidian District, Beijing 100081, China"
            },
            {
                "name": "Dong Shuwen",
                "org": "Institute of Geomechanics, Chinese Academy of Geological Sciences, 11, Minzu Daxue Nanlu, Haidian District, Beijing 100081, China"
            }
        ],
        "venue": "Journal of Geodynamics",
        "year": 2003
    },
    "aaYZZYf4": {
        "id": "aaYZZYf4",
        "title": "Analysis on Current Issues and Open Questions in Cognitive Load Research",
        "abstract": "Cognitive load theory is one of the most influential theories in instructional design.However,several issues arise when delving deeper into the theory.First,there is a need to clarify the relation between cognitive load and learning,so we should explore the effect of the individual differences that can potentially affect working memory and regulate cognitive processing on cognitive loads.Second,there is a need to clarify the definitions of the three cognitive loads,relating them with the specific educational goals of instruction,and considering individual differences in prior knowledge,working memory capacity,and domain-specific abilities,and strengthening empirical research on direct measure of cognitive load.Third,it should be assumed explicitly about the architecture of working memory and its relation to cognitive load,and the additivity should be revised based on the different subsystems of working memory model.Fourth,cognitive load research should accept and use other methods that can increase the external validity,and extend well-defined domains to ill-defined domains.",
        "keywords": [
            "working memory",
            "cognitive load",
            "external validity",
            "additivity hypothesis"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Journal of Southwest China Normal University(Natural Science Edition)",
        "year": 2011
    },
    "lVYcUlzQ": {
        "id": "lVYcUlzQ",
        "title": "An Analysis of the Broader Characteristic of Terahertz Wave Radiation from SI-GaAs Photoconductive Antennas",
        "abstract": "This paper introduces a self-consistent multi-particle Monte Carlo approach for simulating the time-resolved terahertz radiation from SI-GaAs photoconductive antenna.Optical pulse energy and width adjustable femtosecond laser in the model are adopted as the triggering light resources.The simulated THz electromagnetic waveform is found to be basically identical with that obtained from the experiments.Through the dynamic transporting characteristics of carriers within the photoconductor,the radiation THz pulse width is analyzed in comparison with the width of pump pulse,whose physical mechanism lies in: in the biased electrical field,the photo-generated carriers from initial state to the speed reaching the stable state must experience the momentum and energy relaxation.It is just the process of carrier momentum and energy relaxation that leads to the widening of THz wave radiation by photoconductive antenna.In the case of high energy optical and the low biased electric field,the space electric charge field is the main reason to cause the THz waves of photoconductive antenna to appear the bipolar.",
        "keywords": [
            "Monte Carlo simulation",
            "current surge model",
            "semi-insulating GaAs",
            "photoconductive dipole antenna",
            "Terahertz radiation"
        ],
        "authors": [
            {
                "name": "JIA Wan-li",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China;State Key Laboratory of Functional Materials of Microsystems for Informatics,ShangHai Institute of Microsystem and Information Technology,Chinese Academy of Science,Shanghai ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2007
    },
    "Sk2PepAV": {
        "id": "Sk2PepAV",
        "title": "Influence of Jiawei Fuzi Lizhong Extract Granule on Apoptosis of Renal Tubular Epithelial Cells in Aristoloch Acid Nephropathy Rats",
        "abstract": "Objective: To investigate the effect of Jiawei Fuzi Lizhong granule preparation on Bcl-2 and Bax gene expression in rats with aristolochic ACID nephropathy(AAN).Method: Ninety SD rats were divided into 5 groups randomly: normal control group(n=10),model group(n=20),Jiawei Fuzi Lizhong group(n=20),prednisone group(n=20),and Jiawei Fuzi Lizhong plus prednisone group(n=20).Experimental model of AAN was established by intragastric administration of aristoloch acid(100 mg·kg-1·d-1) for three days in SD rats.Rats in each group were intragastric administrated of distilled water(10 mL·kg-1·d-1),distilled water(10 mL·kg-1·d-1),Jiawei Fuzi Lizhong granule preparation(10 mL·kg-1·d-1),prednisone(0.5 mg·kg-1·d-1),and Jiaweifuzilizhong granule preparation(10 ml·kg-1·d-1) plus prednisone(0.5 mg·kg-1·d-1),respectively.Three weeks later,Bcl-2 and Bax expression was examined.Renal tubular epithelial cells apoptosis was determined by TUNEL method.Result: Bcl-2 mRNA and protein expressions were obvious decreased,while Bax expressions increased.There was significant difference in Bcl-2 and Bax expressions between model group and the other experimental groups(P<0.05).Jiawei Fuzi Lizhong granule preparation plus prednisone group showed the strongest effect(P<0.05).The renal tubular epithelial cells apoptosis was obvious in model group.There were statistic differences in renal tubular epithelial cells apoptosis between model group and the other experimental groups(P<0.05).The Jiawei Fuzi Lizhong granule preparation plus prednisone group had the best effect on alleviating apoptosis(P<0.05).Conclusion: The Jiawei Fuzi Lizhong granule preparation had effect on reducing apoptosis rate in AAN rats.Furthermore,combination of Jiawei Fuzi Lizhong granule preparation and prednisone showed the best effect.",
        "keywords": [
            "Bax",
            "apoptosis",
            "Bcl-2",
            "aristolochic acid nephropathy",
            "Jiawei Fuzi Lizhong granule preparation"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,The First Affiliated Hospital Of Guangxi Traditional Chinese Medical University, Nanning ,China"
            },
            {
                "name": "HUANG Ren-fa",
                "org": "Department of Nephrology,Ruikang Hospital Of Guangxi Traditional Chinese Medical University,Nanning ,China"
            },
            {
                "name": "CHEN Yan-qiang",
                "org": "Department of Nephrology,The First Affiliated Hospital Of Guangxi Traditional Chinese Medical University, Nanning ,China"
            }
        ],
        "venue": "Chinese Journal of Experimental Traditional Medical Formulae",
        "year": 2011
    },
    "xp6kXARj": {
        "id": "xp6kXARj",
        "title": "Clinical observation on efficacy of jiaweifuzilizhongtang used for treating aristolochic acid nephropathy",
        "abstract": "Objective:To observe the efficacy of jiaweifuzilizhongtang on the renal function and clinical symptoms of patients with aristolochic acid nephropathy(AAN).Methods:Twenty-seven patients with AAN were treated with jiaweifuzilizhongtang.The observation indexes such as blood urea nitrogen(BUN),serum creatinine(SCr),endogenous creatinine clearance rate(CCr),erythrocyte(RBC),hemoglobin(Hb),twenty-four-hour proteinuria quantitation(24 h Upro),N-acety-β-D-glocosamidase(NAG),Urine Osmole(Uosm),were determined before and after treatment,and the score of patients' symptoms including aversion to cold,cold limbs,fatigue,weakness,anorexia,nausea,pale complexion and lassitude in loin and legs were also calculated.Results:Compared with that of pre-treatment,the renal function of patients after treatment was significantly improved(P<0.05)according to the indexes of BUN,SCr,CCr,RBC and Hb,24 h Upro,NAG,Uosm.Meanwhile,after treatment the score of clinical symptoms was obviously different(P< 0.05)from that of pre-treatment,and the total clinical effective rate was 74.07%.Conclusion:Jiaweifuzilizhongtang is effective for treating the patients with aristolochic acidnephropathy(AAN).",
        "keywords": [
            "clinical observation",
            "jiaweifuzilizhongtang",
            "aristolochic acid nephropathy"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "Wu Jinyu",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "Xie Yongxiang",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "Li Zhenzhong",
                "org": "First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,China"
            }
        ],
        "venue": "Adverse Drug Reactions Journal",
        "year": 2006
    },
    "T8zrMgRw": {
        "id": "T8zrMgRw",
        "title": "Isolation,culture,cryopreservation and resuscitation of human glioma cells",
        "abstract": "Objective To investagate the way of isolating and culturing human glioma cells.Methods The human glioma cells isolated from 30 glioma patients were cultured primarily by enzymatic digestion culture method and identified by molecular markers of glial fibrillary acidic protein(GFAP).The glioma cells were eryopreserved in liquid nitrogen,and then resuscitated on the 1st,4th,8th,12th,16th,20th and 24th week,respectively.The survival rates of cells after resuscitation were observed.Results The primary human glioma cells could be successfully isolated and cultured.The survival rates on the 1st,4th,8th,12th,16th,20th and 24th week were 54%,52%,52%,50%,48%,46%,40%,respectively.The cultured cells after resuscitation growthed well.Conclusion The human glioma cells can be cultured by enzymatic digestion culture method,which can be eryopreserved for a certain period of time and successfully resuscitated and recultured.",
        "keywords": [
            "Human glioma cells"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "CHEN Juan",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "LV Chenglin",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            },
            {
                "name": "CHEN J",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong ,CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2010
    },
    "kNpJ7mLl": {
        "id": "kNpJ7mLl",
        "title": "The inhibitive effects of 1,25(OH)_2D_3 on lipopolysaccharide-induced proteinuria in mice",
        "abstract": "Objective To investigate the effect of 1,25(OH)2D3 on the lipopolysaccharide(LPS)-induced proteinuria of mouse in vivo. Methods Twenty-four C57BL/6 male mice were randomly divided into three groups: normal Sham group(Sham group),LPS induced group(LPS group) and 1,25(OH)2D3 treated group(Treatment group).Intraperitoneally injection of LPS(first day 200 μg,second day 100 μg) was given to the subjects in LPS group and Treatment group,while replaced LPS-free saline was given in Sham group.The 1,25(OH)2D3 [2.5 μg/(kg·d) for 2 days] lavage was given to the subjects in Treatment group,2 days before LPS injection.The 24-hour urine after LPS injection was collected.All subjects were sacrificed on the third day. Results The proteinuria were(72.0±35.6),(732.9±233.2) and(412.3±82.7) μg/mg in Sham group,LPS group and Treatment group,respectively;while significant differences were revealed among them.Meanwhile,the uPAR expression was significantly increased in LPS group,which was inhibited by 1,25(OH)2D3 in both protein level and mRNA level in Treatment group. Conclusion LPS-induced proteinuria can be alleviated by 1,25(OH)2D3 via inhibiting uPAR expression.",
        "keywords": [
            "1",
            "podocyte",
            "proteinuria",
            "lipopolysaccharide",
            "25(OH)2D3"
        ],
        "authors": [
            {
                "name": "MA Jian-chao",
                "org": "Guangdong Academy of Medical Sciences"
            },
            {
                "name": "SHI Wei",
                "org": "Guangdong Academy of Medical Sciences"
            },
            {
                "name": "ZHANG Bin",
                "org": "Guangdong Academy of Medical Sciences"
            },
            {
                "name": "MA Juan",
                "org": "Guangdong Academy of Medical Sciences"
            },
            {
                "name": "XIE Shao-ting",
                "org": "Guangdong Academy of Medical Sciences"
            },
            {
                "name": "LIU Xiao-ying",
                "org": "Guangdong Academy of Medical Sciences"
            }
        ],
        "venue": "Guangdong Medical Journal",
        "year": 2012
    },
    "0FDk5ojQ": {
        "id": "0FDk5ojQ",
        "title": "The Research on and Implementation of the Operation System of Soft PLC",
        "abstract": "SoftPLC,which is a new control technique based on PC,has the merits of PC and the features of traditional PLC.This paper mainly introduces the components of the operation system of SoftPLC and the functions of each part,and elaborates its software implementation of each part.",
        "keywords": [
            "virtual machine",
            "I/O interface",
            "communication interface",
            "SoftPLC"
        ],
        "authors": [
            {
                "name": "ZHANG Lei",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2008
    },
    "VIs1dKmI": {
        "id": "VIs1dKmI",
        "title": "The Design of Portable Soil Moisture Tester Based on AT89S52 SCM(Single Chip Microcomputer)",
        "abstract": "This paper introduces the method of design of a portable soil moisture tester,designs a soil humidity test system based on SCM and analog circuit,and expounds its components and operating principles.The test results show that the test system,which possesses higher measuring accuracy,visual display,and easy operation,etc.,can satisfy the requirements of the production practice.",
        "keywords": [
            "operating principle",
            "soil moisture tester",
            "AT89S52 SCM",
            "design method"
        ],
        "authors": [
            {
                "name": "SHI Yong-li",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2011
    },
    "IyU8icXt": {
        "id": "IyU8icXt",
        "title": "Metallogenic Age of the Super-Large Aktogai Porphyry Copper Deposit, Kazakhstan, and Its Exhumation History",
        "abstract": "The super-large Aktogai porphyry copper deposit is one of three porphyry copper deposits in the Aktogai ore field in the Balkhash metallogenic belt, Kazakhstan, Central Asia. In this study, zircon SHRIMP, 40Ar/39Ar and fission track (FT) dating, together with metallogenic data from previous studies, reveals the whole thermal history from the intrusion of plutons and porphyry copper metallogenesis, and regional cooling, to the exhumation of the deposits. Zircon SHRIMP dating of granitoids from the Aktogay ore field gives a crystallization age of 335.7±1.3 Ma for quartz diorite from the Cole-Dahl intrusion body, and of 327.5±1.9 Ma for the Cu-bearing porphyry granodiorite from the Aktogay deposit. These two ages represent the age of main ore-forming stage of the Aktogai porphyry Cu deposit. 40Ar/39Ar thermochronology of hornblende, biotite, and K-feldspar gives the mineral cooling ages of 310.6 Ma, 271.5 Ma, and 274.9 Ma, respectively, further constraining the porphyry Cu mineralization and regional cooling history. Apatite FT dating of granitoids yields low temperature cooling ages of 91 Ma and 68.0 Ma, suggesting that the Aktogai ore field had undergone the differential uplifting and exhumation resulting from regional tectonic activity during the Late Cretaceous.",
        "keywords": [
            "40Ar/39Ar",
            "metallogenic age",
            "Aktogai copper ore field",
            "Balkhash metallogenic belt",
            "fission track",
            "SHRIMP U-Pb"
        ],
        "authors": [
            {
                "name": "LI Yong",
                "org": ") 1) Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "CHEN Xuanhua",
                "org": ") 1) Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "DONG Shuwen",
                "org": ") 1) Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "WANG Zhihong",
                "org": " Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "CHEN Zhengle",
                "org": " Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "HAN Shuqin",
                "org": " Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "YANG Yi",
                "org": "Laboratory of Geological Formations; Geological Survey Team No.1, Xinjiang Bureau of Geological Exploration, Urumqi, "
            },
            {
                "name": "YE Baoying",
                "org": "K.Satpaev Institute of Geological Sciences; China University of Geosciences, Beijing, "
            },
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "CHEN Wen",
                "org": " Institute of Geology, Chinese Academy of Geological Sciences, Beijing, "
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2012
    },
    "HyDCzI8N": {
        "id": "HyDCzI8N",
        "title": "The Implementation of Basic Graphics Bank of SCADA",
        "abstract": "The SCADA system, which is the automatic system with the most basic functions, has been widely applied in automation field. This paper designs an method for implementing the basic graphics bank of SCADA with VisualC++ 6.0.",
        "keywords": [
            "SCADA",
            "basic graphics bank",
            "automatic system"
        ],
        "authors": [
            {
                "name": "HE Yan-long",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2008
    },
    "cXMfDkTr": {
        "id": "cXMfDkTr",
        "title": "The Jurassic deformation in the Dabie Mountains and its tectonic significances.",
        "abstract": "It was widely accepted that the Dabie orogen underwent an ultrahigh-pressure metamorphism as a result of the Triassic collision between the North China and Yangtze continents.However,there has been much debate on the deformation within the orogen and tectonic setting during the Jurassic.The study on the folding of the pre-Jurassic strata and deep reflection seismic exploration in the foreland belt,the SE deformation of amphibolite facies in the high- and ultrahigh~pressure rocks,and the igneous records of 160～120 Ma in the orogen suggest that a strong orogeny took place in the Dabie Mountains in the middle Jurassic.The orogeny was related to the Yanshanian movement.Because the North China and Yangtze blocks have collided and formed an uniform continent in Triassic,the Jurassic deformation was of intra-continental origin.A separation of Jurassic deformation from the Triassic collisional process of the Dabie Mountains could reasonably explain the second exhumation of ultrahigh-pressure metamorphic rocks from the mantle-crust boundary to the upper crust,the genesis of migmatization at 150 Ma and magmatic activity at 130～120 Ma,and the offset of MOHO in the Dabie foreland belt.",
        "keywords": [
            "Dabie Mountains",
            "Intra-continental orogen",
            "Jurassic"
        ],
        "authors": [
            {
                "name": "DONG ShuWen",
                "org": ""
            },
            {
                "name": "HU JianMin",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "LI SanZhong",
                "org": "College of Geosciences,Ocean University of China,Qingdao ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "GAO Rui",
                "org": "Institute of Geology,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "Xiaochun Liu",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "XUE HuaiMin",
                "org": "Institute of Geology,Chinese Academy of Geological Sciences,Beijing ,China"
            }
        ],
        "venue": "Acta Petrologica Sinica",
        "year": 2005
    },
    "UYgzxATk": {
        "id": "UYgzxATk",
        "title": "Complete mitochondrial genome sequences of three rhombosoleid fishes and comparative analyses with other flatfishes (Pleuronectiformes)",
        "abstract": "Abstract Background Peltorhamphus novaezeelandiae, Colistium nudipinnis, and Pelotretis flavilatus belong to the family Rhombosoleidae of Pleuronectiformes. Their high phenotypic similarity has provoked great differences in the number and nomenclature of the taxa that depend primarily on morphological features. These facts have made it necessary to develop molecular markers for taxonomy and phylogenetic studies. In this study, the complete mitogenomes (mtDNA) of the three rhombosoleid fishes were determined for the comparative studies and potential development of molecular markers in the future. Results The lengths of the complete mitogenome of the three flatfishes are 16,889, 16,588, and 16,937 bp in the order mentioned above. The difference of lengths mainly results from the presence of tandem repeats at the 3′-end with variations of motif length and copy number in the control regions (CR). The gene content and arrangement is identical to that of the typical teleostean mtDNA. Two large intergenic spacers of 28 and 18 bp were found in P. flavilatus mtDNA. The genes are highly conserved except for the sizes of ND1 (which is 28 bp shorter than the two others), ND5 (13 bp longer), and tRNA Glu (5 bp longer) in P. flavilatus mtDNA. The symbolic structures of the CRs are observed as in other fishes, including ETAS, CSB-F, E, D, C, B, A, G-BOX, pyrimidine tract, and CSB2, 3. Conclusions Comparative genomic analysis within rhombosoleids revealed that the mitogenomic feature of P. flavilatus was significantly different from that of the two others. Base composition, gene arrangement, and CR structure were carried on in the 17 mitogenomes. Apart from gene rearrangement in two tongue soles (Cynoglossus semilaevis and Cynoglossus abbreviatus), the gene order in 15 others is identical to that of the typical fish mitogenomes. Of the 16 studied mitogenomes, 15 species (except for Zebrias zebrinus) have tandem repeats at the 3′-, 5′-, or both 3′- and 5′-ends of the CRs. Moreover, the motif length and copy number intraspecies or interspecies are also variable. These phenomena fully indicate the diversity of repeats in flatfish mtDNA and would provide useful data for studies on the structure of mitogenomes in fishes.",
        "keywords": [
            "Peltorhamphus novaezeelandiae",
            "Colistium nudipinnis",
            "Pelotretis flavilatus",
            "mtDNA"
        ],
        "authors": [
            {
                "name": "Shu-Ying Wang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China"
            },
            {
                "name": "Xian-Guang Miao",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China"
            },
            {
                "name": "Xiao-Yu Kong",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510301, China"
            }
        ],
        "venue": "Zoological Studies",
        "year": 2014
    },
    "2UynGgmK": {
        "id": "2UynGgmK",
        "title": "Impacts of Volunteering on Well-being",
        "abstract": "Volunteering involves freely chosen helping activities that extend over time and that are often performed through organizations and on behalf of receptive causes or individuals.Volunteering can promote well-being by means of maintaining physical and mental health,changing coping styles and improving the living conditions.Theories of social integration,psychological resources and perspective-taking thinking explain the mechanism that volunteering acts on well-being to some extent.Some investigates have focused on the effects which reflect on volunteers' well-being,but not explicitly examine the influence on that of recipients' and the reciprocal effects of personal well-being and volunteer services,so more research is needed in these areas.",
        "keywords": [
            "physical and mental health",
            "well-being",
            "satisfaction",
            "volunteering",
            "coping"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            },
            {
                "name": "LI Lin",
                "org": "School of Culture and Social Development Studies,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2010
    },
    "9naFp3b9": {
        "id": "9naFp3b9",
        "title": "Exposure to 2,3,7,8-tetrachlorodibenzo-paradioxin (TCDD) hampers the host defense capability of a bivalve species, Tegillarca granosa.",
        "abstract": "Though increasing reports of deleterious impacts of dioxins and polychlorinated biphenyls (PCBs) on a variety of marine organisms have been described, their effects on the host defense capability of marine bivalve mollusks remain poorly understood. In the present study we used 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) as a representative of dioxins and PCBs to investigate its impacts on the host defense capability of the blood clam, Tegillarca granosa. After exposure of clams to a range (0, 0.01, 0.1, 1, and 10 μg/L) of TCDD for 96 h, the total count, cell type composition, and phagocytic rate of haemocytes were analyzed. In addition, alkaline phosphatase (ALP) activity, cell viability, and the extent of DNA damage of haemocytes were also investigated. Our results showed that exposure to relatively high TCDD concentrations led to significant reductions in the total count and phagocytic activity of haemocytes, which could be accounted by aggravated DNA damage and reduced cell viability. In addition, the percentage of red granulocyte was significantly decreased whereas that of basophil granulocyte was significantly increased upon high doses TCDD exposure (effective concentrations are 1 μg/L and 10 μg/L for red and basophil granulocytes, respectively). Moreover, clams exposed to TCDD had a significant higher activity of ALP, may also indicate an enhanced ability to eliminate pathogens through direct dephosphorylation process whereas a suppressed inflammatory response through indirect regulating of downstream molecular cascade reaction. These findings suggest that TCDD may hamper the host defense capability and therefore render bivalve mollusks more vulnerable to pathogen infections.",
        "keywords": [
            "Blood clam",
            "Haemocytes",
            "Host defense mechanism",
            "TCDD"
        ],
        "authors": [
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Xiaofan Guan",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "Fish & shellfish immunology",
        "year": 2018
    },
    "HEXs5URQ": {
        "id": "HEXs5URQ",
        "title": "Necroptosis, a novel form of caspase-independent cell death, contributes to renal epithelial cell damage in an ATP-depleted renal ischemia model.",
        "abstract": "Acute kidney injury (AKI) induced by renal ischemia is a common clinical problem associated with a high morbidity and mortality. The present study investigated whether necroptosis was present in an in vitro renal ischemia model and whether the addition of necrostatin-1 (Nec-1) has a protective effect. In addition, whether autophagy was inhibited following the use of Nec-1 was also examined. When apoptosis was inhibited by z-VAD‑fmk and energy was depleted with antimycin A for 1 h, the morphological abnormalities of human proximal tubular epithelial (HK-2) cells were markedly attenuated, and the cell viability was significantly improved following incubation with Nec-1. LC3-II/I ratios and LC3-II/GAPDH ratios demonstrated a statistically significant decrease in the Nec-1 + tumor necrosis factor (TNF)-α + z-VAD-fmk + antimycin A (1 h) group compared with the control group. In conclusion, the present study suggested that necroptosis was present in HK-2 cells subjected to TNF-α stimulation and energy depletion. Nec-1 inhibits a caspase‑independent necroptotic pathway involving autophagy and may have therapeutic potential to prevent and treat renal ischemic injury.",
        "keywords": [
            "oncology",
            "gene",
            "molecular medicine",
            "apoptosis",
            "cancer",
            "cell cycle",
            "cell"
        ],
        "authors": [
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Yuanhan Chen",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Li Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Fen Jiang",
                "org": "Department of Nephrology, Central Hospital of Hengyang, Hengyang, Hunan 421001, P.R. China."
            },
            {
                "name": "Wenjian Wang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Zhiming Ye",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Shuangxin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Chunping Yu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, P.R. China."
            }
        ],
        "venue": "Molecular medicine reports",
        "year": 2014
    },
    "6iNduhTs": {
        "id": "6iNduhTs",
        "title": "Complete Mitochondrial Genome of the Nemertean Lineus alborostratus(Nemertea: Heteronemertea)",
        "abstract": "The complete mitochondrial genome of Lineus alborostratus was sequenced and binformation analysis was made.As seen in most metazoans,the genome(15476 bp in length) encodes 13 protein coding genes,2 ribosomal RNA genes and 22 transfer RNA genes,and contains a 747 bp non-coding region.All genes except two tRNAs(trnT and trnP) are encoded on a heavy strand.Nucleotide composition of the genome is biased toward A and T.The protein genes prefer to use the T-rich codons.All protein-coding genes start with ATG and most of them stop by TAA or TAG.The genes nad1,nad2 and cytb appear to use T as an incomplete stop codon.All predicated 22 tRNA genes have the typical clover structures.Special stem-loop structure was not detected in the main non-coding region,but a 37 bp stem-loop structure was detected in nad4 gene.The gene arrangement,initiation codons and anti-codons in L.alborostratus are identical to those of Lineus viridis.Lengths of rrnL and the non-coding region are obviously different between the two Lineus species.L.alborostratus bears fewer nucleotide insertions than L.viridis.",
        "keywords": [
            "tRNA secondary structure",
            "Lineus alborostratus",
            "Nemertea",
            "codon usage",
            "mitochondrial genome"
        ],
        "authors": [
            {
                "name": "XU Dong-Li",
                "org": "Institute of Evolution and Marine Biodiversity,Ocean University of China,Qingdao ,China"
            },
            {
                "name": "CHEN Hai-Xia",
                "org": "Institute of Evolution and Marine Biodiversity,Ocean University of China,Qingdao ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Institute of Evolution and Marine Biodiversity,Ocean University of China,Qingdao ,China"
            },
            {
                "name": "SUN Shi-Chun",
                "org": "Institute of Evolution and Marine Biodiversity,Ocean University of China,Qingdao ,China"
            }
        ],
        "venue": "Periodical of Ocean University of China",
        "year": 2012
    },
    "OVp6HSIW": {
        "id": "OVp6HSIW",
        "title": "Analysis of 121 cases of gastrointestinal mesenchymal tumors by miniprobe endoscopic ultrasonography",
        "abstract": "Objective To evaluate the diagnostic value of miniprobe endoscopic ultrasonography(mEUS)for gastrointestinal mesenchymal tumors.Methods We compared miniprobe endoscopic ultrasonography(mEUS)and pathological results of 121 cases of gastrointestinal mesenchymal tumors(GIMT).Results Among the 121 cases of conventional pathology plus immunohistochemistry confirmed GIMT,there were 65 cases of gastrointestinal stromal tumors,51 cases of leiomyoma and 5 cases of leiomyosarcoma,among which 102 cases were diagnosed by mEUS.The qualitative diagnostic accuracy of mEUS was 84.29%,the localization diagnostic accuracy of mEUS was 95.86%,and the accuracy of differential diagnosis between benign and malignancy was 75%.Conclusions As mEUS can visualize gastric wall layers while detect depth of tumor invasion,it is of certain diagnostic significance for GIMT.",
        "keywords": [
            "Diagnosis",
            "Miniprobe endoscopic ultrasonography",
            "Gastrointestinal mesenchymal tumors"
        ],
        "authors": [
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            },
            {
                "name": "SUN Xiao-bin",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            },
            {
                "name": "TANG Yu",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            },
            {
                "name": "LI Yu",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            },
            {
                "name": "XI Wei-dong",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Second Affiliated Hospital of Chengdu of Chongqing Medical University,Chengdu ,China"
            }
        ],
        "venue": "Practical Journal of Clinical Medicine",
        "year": 2011
    },
    "TvLikDKJ": {
        "id": "TvLikDKJ",
        "title": "RESEARCH STATUS IN ENVIRONMENTAL ARCHAEOLOGY AND ENVIRONMENTAL CHANGE IN THE YUDONG RIVER VALLEY AND THE SANXIA REGION SINCE THE NEOLITHIC AGE",
        "abstract": "Up to now,some research achievements in environmental archaeology and environmental changes in Yudong River Valley and Sanxia Region have been obtained,in relation to ancient environment,environmental change and ancient flood.However,the researched cultural sites are limited in several sub-rivers.As for further research,it is necessary to strengthen the practice and combination of theory and methodology between archeology and Quaternary geomorphology.In the meantime,we must emphasize the research of environmental archaeology,in which the archaeological ruins can reflect the interactions between ancient mankind and environment,including the ecological conditions and environmental qualities of the ancient mankind survival environment,as well as its impact on the environment.We then have to pay attention to the \"secondary accumulation\" research of the sites and the multi-factor analysis of the \"invent layers\",and to the research of global change in order to establish the environment evolutional sequence pertaining to a region.Comparative study should also be carried out between natural accumulation and cultural heritages in these regions.It is proposed that samples with multi-proxy and high-resolution should be accumulated for further research in these regions.",
        "keywords": [
            "environmental change",
            "Yudong River Valley and Sanxia Region",
            "environmental archaeology",
            "Neolithic Age"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;Department of Geography,Jiangsu Institute of Education,Nanjing ,China"
            },
            {
                "name": "ZHU Cheng",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "WANG Fu-bao",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "TIAN Xiao-si",
                "org": "Department of Urban and Resources Sciences,Nanjing University,Nanjing ,China;Tourism Department of Guichi Normal College,Guichi ,China"
            }
        ],
        "venue": "Resources and Environment in the Yangtze Basin",
        "year": 2007
    },
    "AKbJzZmA": {
        "id": "AKbJzZmA",
        "title": "METHOD, APPARATUS, AND SYSTEM FOR THIN DIE THIN THERMAL INTERFACE MATERIAL IN INTEGRATED CIRCUIT PACKAGES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "edward a zarbock",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2007
    },
    "C2Jt4ss9": {
        "id": "C2Jt4ss9",
        "title": "Dynamic analysis of Tension Leg Platform for 5MW floating offshore wind turbine",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "minoh hwang",
                "org": ""
            },
            {
                "name": "sangkwon na",
                "org": ""
            },
            {
                "name": "taewon kang",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            },
            {
                "name": "changwan kim",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2013
    },
    "kzQCISa1": {
        "id": "kzQCISa1",
        "title": "Research on Structure and Electric-Optic Characters of Ga2As Clusters",
        "abstract": "Geometric structures stability and electric-optic characters of Ga2As,Ga2As-and Ga2As+ clusters are studied by the density functional theory(DFT) and on the basis of the B3LYP/6-31G* level,so as to obtain the ground state and sub-state structures of each cluster.The calculated vibrating frequencies of clusters are found to be in good coincidence with the experimental results.The analytical results show that static coulomb function between electrification atoms has induced an aberrance of ion clusters ground state geometric structures and affected electric-optic characters of the clusters.",
        "keywords": [
            "geometric structures",
            "density functional theory(DFT)",
            "Ga2As clusters",
            "electric-optic character"
        ],
        "authors": [
            {
                "name": "MA De-ming",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "LI En-ling",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2009
    },
    "be97wtZ0": {
        "id": "be97wtZ0",
        "title": "Calculation of unbalanced tension and vertical spacing under the condition of uneven ice-covering and ice-shedding",
        "abstract": "Owing to the tension difference produced by both sides,the suspension tower will cause the continuous tower failure under the difference periods of ice-covering rate or ice-shedding for the continuous spans of strain section.Based on the qualitative graphical method,MATLAB numerical iteration method,theoretical simulation and examples,the paper analyzes the influence degree of unbalanced tension by the ice-covering position,the ice-covering rate,terrain,wire attribution,and so on.The Hydro-Quebed suppressor analyzes the jump height of endanger vertical line spacing under the condition of uneven ice-shedding for the condutors with the same the distance.The line anti-ice design and deicing workers should be consider comprehensively the various factors with effecting the unbalanced tension and emphasize the vertical spacing checking.",
        "keywords": [
            "unbalanced tension",
            "uneven ice-covering and ice-shedding",
            "vertical spacing"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "LI Yan-xia",
                "org": ""
            },
            {
                "name": "SUN Zi-tang",
                "org": ""
            }
        ],
        "venue": "Water Resources & Hydropower of Northeast China",
        "year": 2010
    },
    "r7nFEDBE": {
        "id": "r7nFEDBE",
        "title": "Effect of promoting blood circulation by removing blood stasis on serum transforming growth factor-β1,interleukin-4 and interleukin-10 levels in female rats with chronic pelvic inflammatory disease",
        "abstract": "Objective:To explore the effect of promoting blood circulation by removing blood stasis on serum transforming growth factor-β1(TGF-β1),interleukin-4(IL-4) and interleukin-10(IL-10) levels in female rats with chronic pelvic inflammatory disease.Methods:Mixed bacteria plus mechanical damage method were used to establish rat model of chronic pelvic inflammatory disease,60 rats were divided into model group,high dose cassia tuckahoe capsule group,middle dose cassia tuckahoe capsule group,low dose cassia tuckahoe capsule group and control group randomly,12 rats in each group;12 rats in sham operation group and 12 rats in normal group were also selected.ELISA was used to detect the serum levels of TGF-β1,IL-4 and IL-10 in the seven groups.Results:①The serum level of TGF-β1 in model group was significantly higher than those in normal group and sham operation group(P<0.01);the serum level of TGF-β1 in experimental groups was significantly lower than that in model group(P<0.01 or P<0.05),and the serum levels of TGF-β1 in high dose cassia tuckahoe capsule group and middle dose cassia tuckahoe capsule group were similar to that in normal group(P>0.05);the serum level of TGF-β1 in low dose cassia tuckahoe capsule group was significantly higher than that in control group(P<0.01);the serum level of TGF-β1 in middle dose cassia tuckahoe capsule group was significantly lower than that in high dose cassia tuckahoe capsule group and low dose cassia tuckahoe capsule group.②The serum levels of IL-4 and IL-10 in model group were significantly lower than those in normal group and sham operation group(P<0.01);the serum levels of IL-4 and IL-10 in middle dose cassia tuckahoe capsule group were significantly higher than those in model group(P<0.01),and the serum levels of IL-4 and IL-10 in middle dose cassia tuckahoe capsule group were similar to those in normal group(P>0.05);the serum levels of IL-4 and IL-10 in middle dose cassia tuckahoe capsule group and high dose cassia tuckahoe capsule group were higher than those in control group,and there was significant difference in the serum level of IL-4(P<0.01),while there was no significant difference in the serum level of IL-10(P>0.05);the serum levels of IL-4 and IL-10 in low dose cassia tuckahoe capsule group were lower than those in control group,and there was no significant difference in the serum level of IL-4(P>0.05),while there was significant difference in the serum level of IL-10(P<0.01);the serum levels of IL-4 and IL-10 in middle dose cassia tuckahoe capsule group were significantly higher than those in high dose cassia tuckahoe capsule group and low dose cassia tuckahoe capsule group.③There was a significant negative correlation between serum TGF-β1 level and serum IL-4,IL-10 levels(P<0.01),there was a significant positive correlation between serum IL-4 level and serum IL-10 level(P<0.01).Conclusion:Promoting blood circulation by removing blood stasis can affect the serum levels of TGF-β1,IL-4 and IL-10 in female rats with chronic pelvic inflammatory disease,and the effect is correlated with the dose of drug,which may be one of the mechanisms of effect of promoting blood circulation by removing blood stasis on treatment of chronic pelvic inflammatory disease and relief of cervical adhesion by its anti-adhesive effect and inflammation-inhibiting effect.",
        "keywords": [
            "Interleukin-10",
            "Interleukin-4",
            "Transforming growth factor-β1",
            "Promoting blood circulation by removing blood stasis",
            "Chronic pelvic inflammatory disease"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " et al.Department of Gynecology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan ,Shandong,China"
            },
            {
                "name": "LIU Rui-Fen",
                "org": " et al.Department of Gynecology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan ,Shandong,China"
            },
            {
                "name": "YANG Xiao-Na",
                "org": " et al.Department of Gynecology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan ,Shandong,China"
            }
        ],
        "venue": "Maternal and Child Health Care of China",
        "year": 2011
    },
    "zhxdZxk7": {
        "id": "zhxdZxk7",
        "title": "The Evaluation of Regional Crustal Stability in Beijing and Tianjin Area",
        "abstract": "With the increasingly enlarged project scale and rapid economic development,regional crustal stability has become one of the important factors restricting urban development in Beijing and Tianjin area.Based on a study and analysis of regional geology,neotectonic activity,modern vertical deformation of the crust,earthquake,modern structural stress field,rock and soil geology,geological hazards and outer power geological action by using Fuzzy mathematic method,it is suggested that four relative stable grades should be classified in this region,i.e.,stable,sub-stable,less stable and instable.",
        "keywords": [
            "fuzzy mathematics",
            "Beijing and Tianjin area",
            "regional crustal stability"
        ],
        "authors": [
            {
                "name": "DU Jianjun",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Science,Beijing "
            },
            {
                "name": "MA Yinsheng",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Science,Beijing "
            },
            {
                "name": "TAN Chengxuan",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Science,Beijing "
            },
            {
                "name": "GONG Mingquan",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Science,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics,Chinese Academy of Geological Science,Beijing "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2008
    },
    "TTytlPEA": {
        "id": "TTytlPEA",
        "title": "Enhanced Thermoelectric Properties of Polyaniline Nanofilms Induced by Self-Assembled Supramolecules.",
        "abstract": "Polyaniline (PANI) is one of the most promising candidates for flexible organic thermoelectric (TE) applications owing to its relatively low cost and high stability. Herein, the self-assembled supramolecule (SAS) (3,6-dioctyldecyloxy-1,4-benzenedicarboxylic acid) was used as an additive and was introduced into PANI films as a template. Raman spectroscopy, X-ray diffraction, and conductive atomic force microscopy analyses demonstrated that the highly ordered chain structure of PANI was achieved by chemical interactions between PANI and the SAS. Moreover, the ordered regions in the PANI-SAS film increased with a decrease in the film thickness. Consequently, the TE properties of PANI-SAS films were not only much higher than those of PANI films, but they also increased with a decrease in film thickness. The maximum TE power factor of the PANI-SAS film reached 31 μW m(-1)  K(-2) , which is approximately six times higher than the power factor of a PANI film with a similar thickness. This work offers a promising way to prepare PANI thin films with enhanced TE properties. ",
        "keywords": [
            "nanostructures",
            "polyaniline",
            "self-assembly",
            "supramolecular chemistry",
            "thermoelectric properties"
        ],
        "authors": [
            {
                "name": "Liming Wang",
                "org": "University of Chinese Academy of Sciences, Beijing, 100049, China."
            },
            {
                "name": "Qin Yao",
                "org": "CAS Key Laboratory of Materials for Energy Conversion, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China. yaoqin@mail.sic.ac.cn."
            },
            {
                "name": "Juanxiu Xiao",
                "org": "Department of Mechanical Engineering, National University of Singapore, Singapore 117576, Singapore."
            },
            {
                "name": "Kaiyang Zeng",
                "org": "Department of Mechanical Engineering, National University of Singapore, Singapore 117576, Singapore."
            },
            {
                "name": "Wei Shi",
                "org": "University of Chinese Academy of Sciences, Beijing, 100049, China."
            },
            {
                "name": "Sanyin Qu",
                "org": "CAS Key Laboratory of Materials for Energy Conversion, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China."
            },
            {
                "name": "Lidong Chen",
                "org": "Shanghai Institute of Materials Genome, Shanghai, 200050, China. cld@mail.sic.ac.cn."
            }
        ],
        "venue": "Chemistry, an Asian journal",
        "year": 2016
    },
    "CO8eC6Fj": {
        "id": "CO8eC6Fj",
        "title": "Dynamic Response Analysis of Icing Jumping for Transmission Tower-line System",
        "abstract": "Aiming at the problem of dynamic response analysis of icing jumping for transmission tower-line system,the model of tower-line system is established by using ANSYS software.And concentrated load method is used to simulate icing.Considering the different situation as icing thickness and ice-shedding rate,we could complete the dynamic analysis so as to determine the influence of ice thickness and ice-shedding rate on vertical displacement of the wire,the maximum horizontal tension and arrival time.The results show that with the increase of icing thickness,the maximum vertical displacement of wire and the maximum horizontal tension increases but the growth rate is different;increase of ice-shedding rate has a little effect of the vertical displacement of the wire,but it has a certain influence of the maximum horizontal tension and the arrival time increases.",
        "keywords": [
            "vertical displacement",
            "ice-shedding rate",
            "horizontal tension",
            "tower-line system",
            "icing thickness"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "DU Bing",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "LI Huijie",
                "org": "Electrical Engineering College,Northeast Dianli University,Jilin ,China"
            }
        ],
        "venue": "Water Resources and Power",
        "year": 2012
    },
    "neAwzLnW": {
        "id": "neAwzLnW",
        "title": "A novel model of double replications and random loss accounts for rearrangements in the Mitogenome of Samariscus latus (Teleostei: Pleuronectiformes).",
        "abstract": "Although more than one thousand complete mitochondrial DNA (mtDNA) sequences have been determined in teleostean fishes, only a few gene rearrangements have been observed, and genome-scale rearrangements are even rarer. However, flatfishes (Pleuronectiformes) have been identified as having diverse types of mitochondrial gene rearrangements. It has been reported that tongue soles and the blue flounder mitogenomes exhibit different types of large-scale gene rearrangements.In the present study, the complete mitochondrial genome of another flatfish, Samariscus latus, was sequenced, and genome-scale rearrangements were observed. The genomic features of this flounder are different from those of any other studied vertebrates, including flatfish species too. The mitogenome of S. latus is characterized by the duplication and translocation of the control region (CR). The genes located between the two CRs are divided into two clusters in which their relative orders are maintained.We propose a \"Double Replications and Random Loss\" model to explain the rearrangement events in S. latus mitogenome. This model consists of the following steps. First, the CR was duplicated and translocated. Subsequently, double replications of the mitogenome were successively initiated from the two CRs, leading to the duplication of the genes between the two CRs. Finally, one of each pair of duplicated genes was lost in a random event.",
        "keywords": [
            "microarrays",
            "proteomics"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,People's Republic of China"
            },
            {
                "name": "Xian-Guang Miao",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,People's Republic of China"
            },
            {
                "name": "Xiao-Yu Kong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, People's Republic of China. xykong@scsio.ac.cn."
            }
        ],
        "venue": "BMC genomics",
        "year": 2014
    },
    "RUW3rwpE": {
        "id": "RUW3rwpE",
        "title": "Poling optimization and optical loss measurement of the polyetherketone polymer films",
        "abstract": "Polyetherketone (PEK-c) guest–host polymer thin films doped with 3-(1,1-dicyanothenyl)-1-phenyl1-4,5-dihydro-1 H -pryazole were prepared. Through in situ second-harmonic generation (SHG), the corona poling temperature was optimized by measuring the temperature dependence of the in situ SHG signal intensity under the poling electric field. The second-order NLO coefficient χ 33 (2) =16.67 pm/V at λ=1064 nm was determined by using the Maker fringe method after poling condition. For the poled polymer films, the lower-order optical waveguide-transmission losses were measured at 632.8 nm. The measurements showed that the optical loss of the fundamental mode is less than 0.5 dB cm −1 for TE polarization. Keywords A. Polymer thin film D. Optical properties E. Light absorption and reflection E. Nonlinear optics PACS 61.40K 81.40T 42.80L 42.65C 1 Introduction The development of thin polymer materials that are suitable for the fabrication of high-speed integrated optical devices is presently a major focus of research in nonlinear optics [1–3] . Significant progress in device design and architecture with implementation of the poled polymer into prototype electro-optical devices has been reported recently [4,5] . However, the unpoled NLO polymer is isotropic, i.e. the orientational distribution of NLO chromophores in the unpoled polymer films is isotropic. The corona-onset poling at elevated temperature (COPET) is a favored technique for producing noncentrosymmetric NLO polymeric films [6] . The NLO activity of poled polymers originated from the chromophores that exhibit a strong NLO effect and from the angular alignment of these chromophores by electric field poling. So, highly efficient poling is necessary to realize large NLO activity. The COPET generally involves heating of the NLO polymer to just below its glass transition temperature ( T g ), applying a large electric field to orient the chromophore molecules, and cooling the NLO polymer while the field is still applied. But the accurate determination of the poling temperature is difficult. We report that the optimized poling temperature can be derived by means of well-controlled corona poling with in situ SHG signal intensity probing for the DCNP/PEK-c polymer system. And the second-order NLO activities of the poled polymer films under the optimal poling condition were determined by using the Maker fringe method. The low optical loss in waveguides is necessary for designing integrated optical devices. Optical waveguide losses result from three different mechanisms: absorption, scattering and radiation. Generally, the determination of waveguide losses consists in measuring the transmitted power according to the waveguide length [7,8] . In this paper, the optical transmission losses of several lower-order TE mode were measured for poled polymer film waveguides by the Model 2010 Prism Coupler (Metricon ® ). 2 Experiments and results Chromophore DCNP is a highly conjugated molecule based on substituted dihydro-pyrazole [9] . The molecular structure of this molecule is shown in Fig. 1(a) . The host polymer PEK-c is a highly transparent polymer with high glass transition temperature T g ∼228°C [9] . Its general structure is shown in Fig. 1(b) . PEK-c is an ideal polymer host for device fabrication because it is mechanically strong, easily processed into low optical loss thin films, and thermally stable up to 400–500°C. DCNP and PEK-c were independently dissolved in 1,2-dichlorethane. When the guest DCNP and the host PEK-c were completely dissolved in 1,2-dichlorethane, the two solutions were mixed together. Then the premixed solutions were filtered through a syringe with an attached 0.2- or 0.45-μm filter. The final polymer solutions can be easily spin-coated onto the indium–tin oxide (ITO) glass substrates ( n =1.5163) to form thin films. The doping concentration of DCNP in percent solid weight is 10% in the polymer system. In order to remove the residual solvent in the polymer films, firstly the films were tempered at 50°C for several hours, then at 85°C for 1 h. The experimental setup of the in situ poling and SH signal measurement is shown in Fig. 2 [10] . When the in situ SHG signal was measured for optimizing the poling temperature by the experimental setup shown in Fig. 2 , the polarized beam of the Q-switched Nd:YAG laser was focussed on the sample with an angle of incidence θ =45°. A voltage (+6 kV) was applied to a tungsten needle located about 1.5 cm above the thin film. Fig. 3 shows the in situ SHG signal intensity ( I 2 ω ) profile when the poling temperature was increased from room temperature (the temperature rising rate is 5°C/min). The in situ SHG I 2 ω profile shown in Fig. 3 is a reproducible result obtained for several samples probed by the experimental setup shown in Fig. 2 . When the temperature is below 165°C, the SHG signal intensity is very small except for the small peak at about 70°C, which is associated with the β transition of the polymer system. We have demonstrated in Ref. [10] why the SHG intensity appears as a peak at about 70°C and decays for temperatures above 70°C. When the temperature is in the narrow range from 165 to 170°C, the SHG signal intensity increases rapidly because more chromophores in the polymer film were oriented along the electric field direction due to the greater mobility of the polymer at this temperature. But the SHG signal intensity decreases quickly when the temperature is above 17°C, which can be regarded as a critical poling temperature. The main reason for the decrease of this SHG signal intensity when the temperature is beyond the critical poling temperature is: the chromophores in the guest–host polymer system sublimate and aggregate (or crystallize) at this high temperature [11] . A dramatic rise of the conductivity of the polymer can occur at this temperature, and results in the decrease of the effective electric field strength in the polymer film [12,13] . So the optimal poling temperature for this polymer film can be measured as 168° which is lower than the glass transition temperature of the investigated polymer system ( T g =180°C) measured by DSC (PE DSC-2C). The glass transition temperature of this DCNP/PEK-c polymer is lower than that of the pure PEK-c polymer due to the higher plasticity induced by the DCNP guest. At the optimal poling temperature of 168°C, the SHG signal intensity was probed when the tungsten needle applied +6 kV voltage. Fig. 4 shows the poling time dependence of the SHG signal intensity. From Fig. 4 , we can see that the SHG signal intensity can reach saturation in a short period of about 400 s. When the poling time passes beyond 400 s at 168°C, the SHG signal intensity decreases gradually due to sublimation, aggregation, decomposition, and oxidation of the chromophores in the polymer film. Fig. 4 indicates that orientation of the chromophores in the polymer films induced by the electric field can be fulfilled in a short period of time at the optimal poling temperature of 168°C. So the optimal poling time can be derived as 400 s at 168°C when the tungsten needle applied +6 kV voltage. According to the above optimal poling conditions, the poling process was carefully designed and carried out. For corona poling, a setup schematically shown in Fig. 5 was used. A voltage of +6 kV was applied to the needle electrode. A grid with a bias voltage of +700 V was used for making the surface-charge distribution uniform. After poling for 400 s at 168°C, the sample was cooled to room temperature maintaining the needle voltage and grid voltage unchanged. The second-order NLO coefficient χ 33 (2) of the poled polymer films can be measured with the Maker fringe method by using the experimental setup shown in Fig. 2 [14] . The SHG signal intensity with respect to the angle of incidence of the fundamental beam can be expressed as [15,16] (1) I 2ω = 512 π 3 A (χ (2) ) 2 I ω 2 t ω 4 T 2ω P 2 (θ) 1 n ω 2 −n 2ω 2 2 sin 2 ψ where ω and 2 ω correspond to the fundamental and second-harmonic frequencies, respectively; I ω and I 2 ω are the optical powers of the fundamental and SHG signals, respectively; A is the cross-sectional area of the fundamental beam; and χ (2) is the appropriate second-order NLO coefficient; t ω and T 2 ω are the Fresnel transmission coefficients; P ( θ ) is a projection factor; n ω and n 2 ω are the refractive indices of the polymer material at frequencies ω and 2 ω , respectively; ψ can be expressed as (2) ψ= π d 2 4 λ (n ω cos θ ω −n 2ω cos θ 2ω ) where d is the thickness of the sample; λ=1064 nm ; θ ω and θ 2 ω are the angles that the refracted beams at frequencies ω and 2 ω , respectively, make with the normal of the sample surface in the sample. When the fundamental beam is linearly polarized parallel to the plane of incidence and monitoring only the component of the second-harmonic signal that is similarly polarized, the Fresnel transmission tensor can be given as (3) t ω = 2 cos θ n ω cos θ+ cos θ ω , (4) T 2ω =2n 2ω (n ω cos θ+ cos θ ω )(n 2ω cos θ ω +n ω cos θ 2ω ) (n 2ω cos θ+ cos θ 2ω ) 3 . Considering the approximate relationship χ 33 (2) =3 χ 31 (2) for the investigated polymer materials, the projection factor can be given as (5) P(θ)= cos 2 θ ω 3 + sin 2 θ sin θ 2ω + 2 3 cos θ ω sin θ ω cos θ 2ω . The films were scanned over a range of ±60° with respect to the direction of the fundamental beam. The refractive index and thickness of the polymer films were measured by using the prism-waveguide method [17,18] . Then the NLO coefficient χ 33 (2) of the poled polymer films can be calculated as 16.67 pm/V at 1064 nm by using Eqs. (1)–(5) and calibrating the experiment with a Y-cut quartz reference sample. The optical losses of the poled waveguides were measured by the Model 2010 Prism Coupler (Metricon ® ) at λ=632.8 nm . The Model 2010 measures the transmission losses of optical waveguides using the fiber method in which the exponential decay of light is measured by a fiber probe scanning down the length of the propagating streak. This method works well provided the guide has some scattering loss to provide a means to sample the attenuated light intensity. In order to make the loss measurement, a thickness-index measurement may be made first to determine the angular location of modes and then the table can be rotated manually to the vicinity of the desired mode. Fig. 6 shows the TE mode spectrum given by the reflected intensity versus the angle of incidence α . In our case, we are only interested in the lower-order modes where the light is completely confined into the polymer waveguide layer. And only the TE guided modes of lower order ( m =0,…,4) were considered. The measured thickness of the poled polymer films is 2.2864 μm. The measured refractive indices are n o =1.7169 and n e =1.7164, respectively, for the poled polymer films. For the lower-order modes ( m =0,…,4) in Fig. 6 , the angles of incidence α and the refractive indices N m for the m -th TE mode are shown in Table 1 . For a waveguide length Z , we can write [19] : (6) I(Z 2 )=I(Z 1 )10 −L(Z 2 −Z 1 )/10 , where L is the transmission loss (unit: dB cm −1 ), I ( Z 1 ) and I ( Z 2 ) the guide intensity at positions Z 1 and Z 2 of the propagating streak. For the m -th mode, the transmission loss of the polymer waveguide can be written as: (7) L m =− 10 Z 2 −Z 1 log 10 I m (Z 2 ) I m (Z 1 ) ( dB cm −1 ). Fig. 7 shows the exponential decay of the m -th mode ( m =0,…,4) measured with Model 2010 by a fiber probe scanning down the length of the propagation streak. The transmission loss of each mode is shown in Table 1 . In our investigation of optical loss, we considered only TE guide modes at λ=632.8 nm . It is clear that optical loss increases with the order of the mode. This fact could be due to mode overlapping and diffusion through the low index barrier. This is proved by the broadening of the higher-order modes. In our measurements, it is reproducible that the optical of the fundamental mode is less than 0.5 dB cm −1 at 632.8 nm for the investigated polymer waveguide. However, nonexponential loss profiles sometimes occur in the measurements of the mode decay for the polymer waveguide. Some waveguides exhibit peaks superimposed on the expected exponential decay pattern of the propagating streak. In almost all cases, these peaks are extremely reproducible and are caused by the scattering of light from localized defects in the guide such as scratches, dust particles, aggregation of chromophores, or other point imperfections in the path of the streak. Another source of nonexponential decay patterns is the nonuniformity of the thickness and the poling effect in the guiding layer, which causes shifts in the effective mode indices and radiation of energy from the guide. For polymer waveguides losses due to this nonuniformity can be more significant than those for inorganic films deposited by sputtering, CVD, etc. If the nonuniformity of thickness or poling effect occurs over an appreciable length of the propagating streak, the intensity peaks can be quite broad, and the essentially exponential nature of the decay profile can be lost. In extreme cases, the guide can even appear to exhibit gain. In order to avoid this loss mechanism in polymer films fabricated as optical waveguide devices, it is important to prepare the polymer films with very small aggregation of chromophores, scratches or other surface imperfections and greatest uniformity of thickness and poling effect. According to our investigations, a grid voltage is necessary for the poling uniformity and high poling efficiency in the poling processes of the polymer films with the COPET method (cf. Fig. 5 ). 3 Conclusions DCNP/PEK-c guest–host polymer films have been prepared by the spin-coating method. By the in situ signal intensity measurement, the optimal poling temperature has been determined for the DCNP/PEK-c films. According to the optimal condition, the polymer films were poled by the corona poling setup that includes a grid voltage. The second-order NLO coefficient χ 33 (2) =16.67 pm/V at λ=1064 nm was determined by the Maker fringe method. The optical transmission losses of several lower-order TE modes have been measured by using the Model 2010 Prism Coupler for the poled polymer films. The optical loss of the fundamental mode is less than 0.5 dB cm −1 at 632.8 nm. And the optical losses increase with the order of the mode for the poled polymer films. Acknowledgements The research was supported by the National Natural Sciences Foundation of China (Grant No.: 69990540). The authors wish to acknowledge the technological help from Dr Zhiling Xu of State Key Laboratory for Materials Modification by Laser, Ion and Electron Beams, Department of Physics, Fu Dan University. References [1] D.M Burland R.D Miller C.A Walsh Chem. Rev. 94 1994 31 [2] S.M Marder B Kippelen A.K.-Y Jen N Peyghambarian Nature 388 1997 845 [3] W Shi C Fang Q Pan X Sun Q Gu Acta Physica Sinica (Overseas Edition) 8 1999 831 [4] L.R Dalton Chemistry & Industry 7 1997 510 [5] A Chen V Chuyanov S Garner H Zhang W.H Steier J Chen J. Opt. Soc. Am. B 6 1989 733 [6] M.A Mortazavi A Knoesen S.T Kowel B.G Higgins A Dienes J. Opt. Soc. Am. B 6 1989 733 [7] P.K Tien Appl. Opt. 10 1971 2395 [8] A Boudriona J.C Lonlergue Opt. Commun. 137 1997 37 [9] W Shi C Fang Q Pan X Sun Q Gu Chin. Phys. Lett. 17 2000 22 [10] W Shi Z Xu C Fang Q Pan Q Gu D Xu H Wei J Yu Solid State Commun. 113 2000 483 [11] A.W Harper S Sun L.R Dalton S.M Garner A Chen S Kalluri W.H Steier J. Opt. Soc. Am. B 15 1998 329 [12] R Blum M Sprave J Sablotny M Eich J. Opt. Soc. Am. B 15 1998 318 [13] A Peled L.B Schein Chem. Phys. Lett. 153 1988 422 [14] K.D Singer J.E Sohn S.J Lalama Appl. Phys. Lett. 49 1986 248 [15] P.D Maker R.W Terhune M Nisenoff C.M Savage Phys. Rev. Lett. 8 1962 21 [16] J Jerphanon S.K Kurtz J. Appl. Phys. 41 1970 1667 [17] B.P Singh P.N Prasad J. Opt. Soc. Am. B 5 1988 453 [18] K Singer L King J. Appl. Phys. 70 1991 3251 [19] R.G Hunsperger Integrated Optics: Theory and Technology 1985 Springer Berlin p. 80",
        "keywords": [
            "electric field",
            "optical waveguide",
            "thin film",
            "second harmonic generation",
            "second order"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hui Hu",
                "org": "Department of Physics, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hongzheng Wei",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Solid State Communications",
        "year": 2000
    },
    "DOIEy4qS": {
        "id": "DOIEy4qS",
        "title": "Position Method and Realization in Electronic Whiteboard",
        "abstract": "In order to solve the problem of whiteboard position,a position method is designed on the basis of an introduction of whiteboard structure and principle of operation.The SCM STC12C52A60S2 is a controlling core in this system,and the detailed implementation steps are given.After testing,the position method achieved good effect.It is able to make operations using specific position pen instead of the mouse and keyboard,such as drawing,editing documents,preservating and any other operations.",
        "keywords": [
            "position method",
            "electronic whiteboard",
            "position pen",
            "STC12C52A60S2"
        ],
        "authors": [
            {
                "name": "ZHAO Liang",
                "org": "(College of Information Engineering,Taiyuan University of Technology,Taiyuan ,China)"
            },
            {
                "name": "SHI Wei",
                "org": "(College of Information Engineering,Taiyuan University of Technology,Taiyuan ,China)"
            }
        ],
        "venue": "Video Engineering",
        "year": 2012
    },
    "6rzvgJb8": {
        "id": "6rzvgJb8",
        "title": "Vacancy defective perovskite Na0.85Ni0.45Co0.55F3.56 nanocrystal anodes for advanced lithium-ion storage driven by surface conversion and insertion hybrid mechanisms",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Tong Yan",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Yuxi Huang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Caini Tan",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Xiujuan Sun",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Ping Gao",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education"
            }
        ],
        "venue": "Chemical Communications",
        "year": 2019
    },
    "Lj8MRCvy": {
        "id": "Lj8MRCvy",
        "title": "First-principles study on stability and photoelectron spectroscopy of Ga(n)As2(n = 1-9) clusters.",
        "abstract": "The stability and photoelectron spectroscopy of the Ga(n)As2(n=1-9) clusters have been studied by using first-principles based on density functional theory (DFT). Our calculations reveal that the stabilities of the Ga(n)As2(n=1-9) clusters tend to increase with the increase of the number of total atoms. The calculated second-order difference values of the binding energy show a certain law of even-odd alternation, and the value of the even-numbered clusters is much larger than those of the odd-numbered ones. The energy gap Egap also shows a certain law of even-odd alternation, i.e. the Egap of the even-numbered clusters is much larger than the odd-numbered ones. The Egap of the clusters is between 0.2 eV and 0.6 eV, it will provide a reference for GaAs defect level research. The Ga(n)As2(n=1-9) clusters are potential to detect and emit THz radiation due to their ground-state vibration frequency are in THz range.",
        "keywords": [
            "Density functional theory",
            "Ga(n)As(2) clusters",
            "Photoelectron spectroscopy",
            "Structure and stability"
        ],
        "authors": [
            {
                "name": "Deming Ma",
                "org": "Department of Applied Physics, Xi'an University of Technology, Xi'an 710054, China."
            },
            {
                "name": "Hongbo Qiao",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Enling Li",
                "org": ""
            },
            {
                "name": "Youheng Ma",
                "org": ""
            },
            {
                "name": "Wei Wang",
                "org": ""
            }
        ],
        "venue": "Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy",
        "year": 2014
    },
    "RhZXoby7": {
        "id": "RhZXoby7",
        "title": "Investigation on a polymeric single-mode optical waveguide",
        "abstract": "By using an indirect method the refractive index of the guest-host polymer thin film made up of DCNP and polyetherketone (PEK-c) was calculated at the wavelength of 1300 nm. On the basis of the study on polymeric slab optical waveguide, a novel single moded polymeric converse-ridge waveguide was designed and fabricated. The results show that this kind of optical waveguide possesses good single-mode property for practical application.",
        "keywords": [
            "Optical waveguide",
            "Polymer thin film",
            "Refractive index dispersion"
        ],
        "authors": [
            {
                "name": "Zhihui Qin",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xin Yin",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "JinZhong Yu",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Guangdianzi Jiguang/Journal of Optoelectronics Laser",
        "year": 2002
    },
    "C7PF5CDz": {
        "id": "C7PF5CDz",
        "title": "The Design and Implementation of Database Technique In the Universal Testing Machine Software Package:TestExpert. NET",
        "abstract": "This article tells of the process on how to apply general Database technology into the design of Universal Static Testing Machine Software.It includes:1.The design of the Database tables structure;2.How to make simple queries and combined queries with ADO.NET;3.How to import and export data from a database with ADO.NET;4.How to use transaction to deal with database.",
        "keywords": [
            "testing machine",
            "transaction",
            "clatabase",
            "ADO.NET"
        ],
        "authors": [
            {
                "name": "Zhang Lixin",
                "org": "Changchun Research Institute for Testing Machine Co.Ltd,Jilin Changchun "
            },
            {
                "name": "Jia Xin",
                "org": "Changchun Research Institute for Testing Machine Co.Ltd,Jilin Changchun "
            },
            {
                "name": "Chen Nan",
                "org": "Changchun Research Institute for Testing Machine Co.Ltd,Jilin Changchun "
            },
            {
                "name": "Shi Wei",
                "org": "Changchun Research Institute for Testing Machine Co.Ltd,Jilin Changchun "
            }
        ],
        "venue": "Engineering & Test",
        "year": 2009
    },
    "mLEiGEu6": {
        "id": "mLEiGEu6",
        "title": "Influence of Three-dimensional Ground Motion Input on IDA-based Collapse Fragility Analysis",
        "abstract": "Collapse safety is the most important objective of performance-based seismic design,and IDA(incremental dynamic analysis)-based collapse fragility analysis is able to quantitatively evaluate structural collapse safety under earthquakes.In this paper,it is illustrated that IDA considering single horizontal component of ground motion will over-estimate structural collapse safety through examples of an 8-storey RC frame structure and a 20-storey RC frame-core wall structure.More collapse modes may be appear with three-dimensional ground motion input,so that more potential seismic vulnerability is clearly exposed.Therefore,IDA considering three-dimensional ground motion input should be adopted for collapse safety evaluation.",
        "keywords": [
            "three-dimensional earthquake ground motion",
            "collapse safety subjected to earthquake",
            "collapse mode",
            "incremental dynamic analysis"
        ],
        "authors": [
            {
                "name": "Lu Xin-zheng",
                "org": "Department of Civil Engineering,Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Civil Engineering,Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Zhang Wan-kai",
                "org": "Department of Civil Engineering,Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Ye Lie-ping",
                "org": "Department of Civil Engineering,Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry,Tsinghua University,Beijing ,China"
            },
            {
                "name": "Ma Yu-hu",
                "org": "Department of Civil Engineering,Key Laboratory of Civil Engineering Safety and Durability of China Education Ministry,Tsinghua University,Beijing ,China"
            }
        ],
        "venue": "Earthquake Resistant Engineering and Retrofitting",
        "year": 2011
    },
    "eZCMf5Cx": {
        "id": "eZCMf5Cx",
        "title": "Universities' Basic Ideas on Constructing Internal Quality Assurance System after First Teaching Evaluation",
        "abstract": "How to build scientific and effective internal quality assurance system has become the focused and difficult problem of current higher education on the theory research and practical exploration.Based on the analysis of first teaching evaluation,the paper identifies limitations of the traditional internal quality assurance system,and proposes basic ideas on constructing the internal quality assurance system in universities:people-orientation and full participation to highlight the subjectivity of system construction;comprehensive management and overall control to outstand the globality of system construction;coordinated operation and dynamic adjustment to realize the sustainable development of system.",
        "keywords": [
            "internal quality assurance system",
            "total quality management",
            "teaching evaluation"
        ],
        "authors": [
            {
                "name": "WANG Jian",
                "org": "Educational Administration Office,Fuyang Normal College,Fuyang,,China"
            },
            {
                "name": "LIU Xue-zhong",
                "org": "School of Literaly,Fuyang Normal College,Fuyang,,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Educational Science,Fuyang Normal College,Fuyang,,China"
            }
        ],
        "venue": "Higher Education of Sciences",
        "year": 2011
    },
    "lJD3CpvI": {
        "id": "lJD3CpvI",
        "title": "Evolution of the Late Cenozoic Tectonic Stress Regime in the Tianshui Basin, Northeast Tibetan Plateau",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "chen peng",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "shi wei",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "yang jiaxi",
                "org": "chang an university"
            },
            {
                "name": "l i jiangyu",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            }
        ],
        "venue": "Acta Geologica Sinica-english Edition",
        "year": 2015
    },
    "MSwNW4t7": {
        "id": "MSwNW4t7",
        "title": "Secondary arc extinction by high speed grounding switches",
        "abstract": "The mechanism of secondary arc extinction by high speed grounding switches (HSGS) is analyzed. The magnitude of the secondary arc current in arc path and that of the recovery voltage after are differently reduced by SGS, which in turn reducing the extinction time of the secondary arc and assuring successful single-pole autoreclosure. The approach is also verified by the transient network analyzer (TNA) test and the calculation of electro magnetic transient program (EMTP).",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Yanhua Han",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Yue Fan",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University",
        "year": 2000
    },
    "eymgICKK": {
        "id": "eymgICKK",
        "title": "The complete mitochondrial genome sequence of Halichoeres nigrescens (Labriformes: Labridae)",
        "abstract": "AbstractThe complete mitochondrial genome of marine fish Halichoeres nigrescens was sequenced by the high-throughput sequencing method. The genome is 17,252 bp in length, consisting of 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. The gene arrangement of Halichoeres nigrescens is identical to that of common fishes. Phylogenetic tree based on 13 protein-coding genes shows that Halichoeres nigrescens has a closer phylogenetic relationship to Macropharyngodon negrosensis than to Halichoeres hartzfeldii.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Life Science, Foshan University, Foshan, Guangdong, China;"
            },
            {
                "name": "Wei Shi",
                "org": "College of Life Science, Foshan University, Foshan, Guangdong, China;"
            },
            {
                "name": "Shixi Chen",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology Chinese Academy of Sciences, Guangzhou, China"
            },
            {
                "name": "Hui Yu",
                "org": "College of Life Science, Foshan University, Foshan, Guangdong, China;"
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "BI4ITg6b": {
        "id": "BI4ITg6b",
        "title": "Fluorogenic boronate-based probe-lactulose complex for full-aqueous analysis of peroxynitrite.",
        "abstract": "A selective fluorogenic boronate-based probe-lactulose complex was evaluated for the rapid analysis of peroxynitrite (ONOO) based on a reaction-based indicator displacement assay (RIA). The probe was synthesised by a simple nucleophilic substitution reaction between a boronic acid moiety and a well known laser dye, DCM. Fluorescence analyses showed that the probe had an off-on response to lactulose, forming a fluorogenic probe-lactulose complex. The subsequent addition of ONOO selectively quenched the fluorescence of the complex over other Reactive Oxygen/ Nitrogen Species (ROS/RNS) tested. The complex can be applied for the rapid determination of ONOO in full aqueous solution with good linear range, and has also proven suitable for monitoring ONOO in living cells and real water samples.",
        "keywords": [
            "DCM",
            "Fluorescent probe",
            "Full aqueous",
            "Lactulose",
            "Peroxynitrite"
        ],
        "authors": [
            {
                "name": "Kai-Bin Li",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China. Electronic address: lkbecust@126.com."
            },
            {
                "name": "Lei Dong",
                "org": "Institut de Chimie et Biochimie Moléculaires et Supramoléculaires,, Laboratoire de Chimie Organique 2 - Glycochimie, UMR 5246, Université Lyon 1 and CNRS, 43 Boulevard du 11 Novembre 1918, F-69622, Villeurbanne, France."
            },
            {
                "name": "Siqi Zhang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Wen-Ping Jia",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "De-Man Han",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China. Electronic address: hdm@tzc.edu.cn."
            }
        ],
        "venue": "Talanta",
        "year": 2017
    },
    "auK5QRz7": {
        "id": "auK5QRz7",
        "title": "Nonlinear optical properties and chromophore electrostatic interactions for the poly(ether ketone) guest-host polymer films",
        "abstract": "The poly(ether ketone) (PEK-c) guest-host system thin films doped with different weight percents of 3-(1,1-dicyanothenyl)-1-phenyl-4,5-dihydro-1H-pryazole (DCNP) were prepared. Their second order nonlinear optical (NLO) coefficients χ33 (2) were measured by using the Maker fringe method through in-situ second-harmonic-generation (SHG) probing. Experimental results indicated that, at high chromophore loading in the polymer system, the second-order NLO properties of the poled polymer films could decrease with increasing chromophore loading. In this paper, the relationship between the macroscopic second-order NLO coefficient and the chromophore number density was investigated by considering the role of the electrostatic interactions of chromophores in the polymer films. According to the improved relationship, the macroscopic second-order NLO coefficient is no longer in a direct ratio with the chromophore number density in the polymer films, especially when the chromophore loading is high. The effect of the electrostatic interactions of chromophores on second-order NLO properties was discussed from the improved relationship.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Zhenyu Zhang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Lina Ye",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Dong Xü",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Hongzhen Wei",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            }
        ],
        "venue": "Macromolecules",
        "year": 2001
    },
    "MoHj4xzL": {
        "id": "MoHj4xzL",
        "title": "Design of Color Recognition System Based on Phase-locked Loop",
        "abstract": "According to the theory of phase-locked loop,we use reflected photoelectric sensor to carry out the color recognition.The method introduced in the paper can be used to lead and orient a robot.The sensor has high sensitivity and well anti-disturbance(capability.)",
        "keywords": [
            "phase-locked loop",
            "color recognition",
            "design"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "YUAN Lei",
                "org": "Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Mechanical Engineering & Automation",
        "year": 2006
    },
    "xY9bn4vw": {
        "id": "xY9bn4vw",
        "title": "In silico study on hydroxylated polychlorinated biphenyls as androgen receptor antagonists.",
        "abstract": "Hydroxylated polychlorinated biphenyls (HO-PCBs), major metabolites of PCBs, may have the potential to disrupt androgen hormone homeostasis. However, there is a lack of systematic investigation into the intermolecular interaction mechanism between HO-PCBs and the androgen receptor (AR). In this study, the combination of three-dimensional quantitative structure-activity relationship (3D-QSAR), molecular docking, and molecular dynamics (MD) simulations was performed to elucidate structural characteristics that influence the anti-androgen activity of HO-PCBs, and to provide a better understanding of the binding modes between HO-PCBs and AR. A predictive comparative molecular field analysis (CoMFA) model was developed with good robustness and predictive ability. Graphical interpretation of the model provided some insights into the structural features that affect the anti-androgen activity of HO-PCBs. The hydrogen bond interaction with Gln711, and hydrophobic interactions with residues in the hydrophobic pocket played important roles in the binding of ligand with receptor. These results are expected to be beneficial to predict anti-androgen activities of other HO-PCBs and provided possible clues for further elucidation of the binding mechanism of HO-PCBs with AR.",
        "keywords": [
            "molecular dynamics simulation",
            "3d -qsar",
            "molecular docking",
            "androgen receptor",
            "ho-pcbs"
        ],
        "authors": [
            {
                "name": "Xiaolin Li",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Li Ye",
                "org": "Suzhou NeuPharma Co., Ltd.(Suzhou NeuPharma Co., Ltd.),Suzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongling Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Chunsheng Liu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiangping Qian",
                "org": "Suzhou NeuPharma Co., Ltd.(Suzhou NeuPharma Co., Ltd.),Suzhou,China"
            },
            {
                "name": "Yongliang Zhu",
                "org": "Suzhou NeuPharma Co., Ltd.(Suzhou NeuPharma Co., Ltd.),Suzhou,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Ecotoxicology and environmental safety",
        "year": 2013
    },
    "abmWtnkN": {
        "id": "abmWtnkN",
        "title": "Influence of electronic type of SWNTs on the thermoelectric properties of SWNTs/PANI composite films",
        "abstract": "Single-walled carbon nanotubes (SWNTs) have emerged as one of the leading additives for improving the thermoelectric properties of organic materials due to their unique structure and excellent electronic transport properties. However, since as-grown SWNTs possess different chirality, it is of high interest to determine the influence of electronic type of SWNTs on the thermoelectric properties of SWNTs/PANI composite films. Herein, we utilized metallic SWNTs (SWNT-M) and semiconducting SWNTs (SWNT-S) to prepare SWNTs/PANI composite films and studied their thermoelectric properties, respectively. Experimentally, the maximum thermoelectric power factor reached 51 μW m−1 K−2 for the 19 wt% SWNT-S/PANI composite films, while that value was only 16 μW m−1 K−2 for the 19 wt% SWNT-M/PANI composite films. The better power factor of SWNT-S/PANI composite films may be attributed to the more significantly enhanced Seebeck coefficient resulting from the effective energy filtering effect at the interfaces between SWNT-S and PANI. Our results reveal the influence of electronic type of SWNTs on the thermoelectric properties of composites, which will drive ongoing efforts to utilize SWNTs as fillers in nanocomposites for optimal thermoelectric properties.",
        "keywords": [
            "Thermoelectric",
            "Metallic SWNTs",
            "Semiconducting SWNTs",
            "Composites"
        ],
        "authors": [
            {
                "name": "Liming Wang",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China"
            },
            {
                "name": "Qin Yao",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China"
            },
            {
                "name": "Sanyin Qu",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China"
            },
            {
                "name": "Wei Shi",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China"
            },
            {
                "name": "Lidong Chen",
                "org": "State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China"
            }
        ],
        "venue": "Organic Electronics",
        "year": 2016
    },
    "Is3cuDFf": {
        "id": "Is3cuDFf",
        "title": "Feasibility study of offshore wind turbine substructures for southwest offshore wind farm project in Korea",
        "abstract": "",
        "keywords": [
            "substructure"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "jonghoon han",
                "org": ""
            },
            {
                "name": "changwan kim",
                "org": ""
            },
            {
                "name": "daeyong lee",
                "org": ""
            },
            {
                "name": "hyunkyoung shin",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            }
        ],
        "venue": "Renewable Energy",
        "year": 2015
    },
    "nvDRIogR": {
        "id": "nvDRIogR",
        "title": "Improvement Of Thermodynamic Modeling Of Calcium Carbonate And Calcium Sulfates At High Temperature And High Pressure In Mixed Electrolytes",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "nan zhang",
                "org": ""
            },
            {
                "name": "zhaoyi dai",
                "org": ""
            },
            {
                "name": "amy t kan",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "mason b tomson",
                "org": ""
            }
        ],
        "venue": "open source systems",
        "year": 2014
    },
    "qejuAmUN": {
        "id": "qejuAmUN",
        "title": "Study on the Antioxidant Effect of Flavored Fried-free Aconite Particles on Acute Aristolochic Acid Nephropathy Rats",
        "abstract": "Objective: To observe the antioxidant effect of flavored fried-free aconite particles on acute aristolochic acid nephropathy rats.Methods: Pure aristolochic acid A was used to induce acute aristolochic acid nephropathy rat models to observe the changes of SOD、MDA levels and the renal pathological changes of the acute aristolochic acid-induced nephropathy rats.Results: The Chinese herbal medicine group could increase SOD of the renal tissue and reduce the expression of MDA of the acute aristolochic acid-induced nephropathy rats.The Chinese herbal medicine group combined with prednisone significantly increased more SOD of the renal tissue and lower more MDA expression(P <0.01) than other groups and reduced the renal pathological damage.Conclusion: The flavored fried-free aconite particles combined with prednisone can improve the oxidative stress in rat kidneys and reduce the renal pathological damage.",
        "keywords": [
            "malondialdehyde",
            "flavored fried-free aconite particles",
            "aristolochic acid nephropathy",
            "superoxide dismutase"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical College,Nanning,Guangxi,"
            },
            {
                "name": "HUANG Ren-fa",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical College,Nanning,Guangxi,"
            },
            {
                "name": "LAN Fang",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical College,Nanning,Guangxi,"
            }
        ],
        "venue": "Yunnan Journal of Traditional Chinese Medicine and Materia Medica",
        "year": 2011
    },
    "orQnElog": {
        "id": "orQnElog",
        "title": "Integrated micro-channels for 3D through silicon architectures",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "yiqun bai",
                "org": ""
            },
            {
                "name": "qing a zhou",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2005
    },
    "WxqfolyJ": {
        "id": "WxqfolyJ",
        "title": "Diagnostic value of urine HBV DNA for hepatitis B virus-associated glomerulonephritis]",
        "abstract": "To investigate the potential value of urine hepatitis B virus (HBV) DNA as a new noninvasive diagnostic indicator for HBV-associated glomerulonephritis (HBV-GN).A total of 152 patients including 66 with HBV-GN, 66 with non-HBV-GN, and 20 with chronic hepatitis B (CHB) without renal disease were examined for serum and urine HBV DNA levels using polymerase chain reaction (PCR) and for 5 serum HBV markers using enzyme-linked immunosorbent assays.Twenty-two patients (33%) in the HBV-GN group, but none in the other two groups, were found positive for urine HBV DNA. In the diagnosis of HBV-GN, urine HBV DNA had a high specificity (0.98), a good positive predictive value (PPV, 0.96), and a modest negative predictive value (NPV, 0.60). Urine HBV DNA, alone or in combination with serum HBeAg, was superior in the diagnosis of HBV-GN to the combination of urine HBV DNA with serum HBV DNA, hepatitis B surface antigen and the hepatitis B e antigen.Urine HBV DNA may be one of the new noninvasive diagnostic criterion for HBV-GN.",
        "keywords": [],
        "authors": [
            {
                "name": "Lifen Wang",
                "org": "Department of Nephrology, Guangdong General Hospital/Guangdong Academy of Medical Sciences, Guangzhou 510080, China. E-mail: 15010942109@139.com."
            },
            {
                "name": "Zhiming Ye",
                "org": ""
            },
            {
                "name": "Lixia Xu",
                "org": ""
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Huaban Liang",
                "org": ""
            },
            {
                "name": "Zhonglin Feng",
                "org": ""
            },
            {
                "name": "Shuangxin Liu",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2014
    },
    "PLhvHGBE": {
        "id": "PLhvHGBE",
        "title": "Emotional Reactions to Historical Injustice Events:Collective Guilt",
        "abstract": "Collective guilt can be conceptualized as guilt that is experienced as a consequence of belonging to a group which has done wrongdoing to the other groups,even though the personal self was clearly uninvolved in the harmful actions.It is a self-focus emotion.Some cognitive factors will affect the group-based guilt,such as in-group responsibility,legitimacy appraisal,perceived difficulty of making restitutions,the personal value priorities and national identity will produce the individual difference in collective guilt.Group-based guilt can facilitate apologies and restitutions to the victimized group.There are ample opportunities to develop whether people can experience collective guilt for present-day behavior that harms in-group members in the future,and the other emotions will integrate with collective guilt in intergroup reconciliation.",
        "keywords": [
            "apology",
            "collective guilt",
            "restitution",
            "national identity"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " School of Culture and Social Development Studies; Center of Studies for Psychology and Social management,Southwest University,Chongqing ,China"
            },
            {
                "name": "YAN Xian-Yang",
                "org": " Library"
            },
            {
                "name": "LIU Jie",
                "org": " Center of Studies for Psychology and Social management,Southwest University,Chongqing ,China"
            }
        ],
        "venue": "Advances in Psychological Science",
        "year": 2011
    },
    "90C9Gznu": {
        "id": "90C9Gznu",
        "title": "Nitrogen-doped TiO2(B) nanorods as high-performance anode materials for rechargeable sodium-ion batteries",
        "abstract": "To achieve better anode materials for sodium ion batteries, a nitrogen-doped TiO2(B) nanorod structure is developed utilizing hydrothermal treatment, ion exchange and a subsequent low temperature calcination process. Transmission electron microscopy, X-ray photoelectron spectroscopy and X-ray diffraction are employed to characterize the structure and properties of the nitrogen-doped TiO2(B). Compared with anatase TiO2 powder (325 mesh) raw materials and the TiO2(B) nanorods without N-doping, the as-fabricated nitrogen-doped TiO2(B) nanorods with a nitrogen-doping amount of 1.23 atom% exhibit higher specific capacity (224.5 mA h g−1), good cycling stability (the capacity retention ratios after 200 cycles at 2C is 93.4%) and enhanced rate capability (110 mA h g−1 at 3.35 A g−1), which is likely to be associated with enhanced conductivity due to N-doping.",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchang Yang",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Shijia Liao",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Wei Shi",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Yundong Wu",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Renhui Zhang",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Senlin Leng",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            }
        ],
        "venue": "RSC Advances",
        "year": 2017
    },
    "8Zl8ST8A": {
        "id": "8Zl8ST8A",
        "title": "Intelligent Transportation Information Sharing and Service Integration in Semantic Grid Environment",
        "abstract": "ITSGrid is an undergoing joint engineering project designed and developed by advanCed Computing aNd sysTem (CCNT) Lab in Zhejiang University and Hangzhou Enjoyor Electronics Co. Ltd (Enjoyor). The new features of ITSGrid are originated from two important research projects -- DartGrid and DartFlow, and one key engineering project -- JTang Application Server, in CCNT Lab. Its goal is to build an integrated intelligent transportation information and service platform (ITISP), to integrate traffic data resources collected by Enjoyor and cooperate existing ITS subsystems and services deployed by Enjoyor, finally serve for transportation construction in China. During building this project, we utilize systematically the Grid technology, the Semantic Web technology, the Web Service technology, the Messaging Oriented Middleware technology.",
        "keywords": [
            "grid technology",
            "intelligent transportation information",
            "integrated intelligent transportation information",
            "important research project",
            "ccnt lab",
            "web service technology",
            "service integration",
            "semantic web technology",
            "hangzhou enjoyor electronics co.",
            "messaging oriented middleware technology",
            "semantic grid environment",
            "joint engineering project",
            "key engineering project",
            "middleware",
            "semantic web",
            "web service",
            "application server",
            "message oriented middleware",
            "transportation",
            "message passing",
            "semantic grid",
            "grid computing"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Jian Wu",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Ying Li",
                "org": "Zhejiang University, China"
            },
            {
                "name": "Li Kuang",
                "org": "Zhejiang University, China"
            }
        ],
        "venue": "Proceedings - 2006 IEEE/WIC/ACM International Conference on Web Intelligence (WI 2006 Main Conference Proceedings), WI'06",
        "year": 2007
    },
    "sEinVRz6": {
        "id": "sEinVRz6",
        "title": "Terahertz Technology: Coherent and Widely TunableTHz and Millimeter WavesBased on Difference-Frequency Generation inGaSe and ZnGeP 2",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "yujie j ding",
                "org": ""
            }
        ],
        "venue": "Optics & Photonics News",
        "year": 2002
    },
    "GceNYKg9": {
        "id": "GceNYKg9",
        "title": "Improved dominating set indices for mobile peer-to-peer networks",
        "abstract": "According to 2-hop neighborhood information, dynamic dominant index set (DDIS) (W. Shi and S. Li, 2005) is constructed to cache metadata of shared resources in mobile ad hoc network (MANET). However, DDIS presents poor performance on system overhead and user satisfaction. To adapt network mobility, peers in DDIS have to periodically advertise their shared resources over the entire network, which consumes more bandwidth. In this paper, an improved dominating set indexing mechanism (IDSIM) for mobile peer-to-peer networks is proposed. In IDSIM, partial dominating sets automatically adjust themselves to the change of network topology in a distributed fashion. Metadata of identical resources belonged to deferent peers is clustered in one dominating set. This potentially increases in amount of query results with short latency to achieve considerable high user satisfaction. Based on random walk (C. Gkantsidis et al., 2004), query message roams in the network to maximize the number of results. Experiments indicate that besides greatly reducing the system overhead, IDSIM simplifies search process and, at the same time, improves user satisfaction without sacrifice of user response time.",
        "keywords": [
            "network mobility",
            "user response time",
            "user satisfaction",
            "query message",
            "system overhead",
            "considerable high user satisfaction",
            "mobile ad hoc network",
            "network topology",
            "dominating set indices",
            "entire network",
            "partial dominating sets",
            "telecommunication network topology",
            "shared resource",
            "mobile peer-to-peer network",
            "2-hop neighborhood information",
            "improved dominating set indexing mechanism",
            "shared resources",
            "metadata caching",
            "graph theory",
            "peer-to-peer computing",
            "improved dominating set indices",
            "ad hoc networks",
            "mobile computing",
            "mobile peer-to-peer networks",
            "indexation",
            "dominating set",
            "random walk"
        ],
        "authors": [
            {
                "name": "Shanping Li",
                "org": "Zhejiang University Hangzhou, P.R.China"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University Hangzhou, P.R.China"
            },
            {
                "name": "Xin Lin",
                "org": "Zhejiang University Hangzhou, P.R.China"
            },
            {
                "name": "Channa Nizamuddin",
                "org": "Zhejiang University Hangzhou, P.R.China"
            }
        ],
        "venue": "international conference on embedded software and systems",
        "year": 2005
    },
    "8Wb1CQsI": {
        "id": "8Wb1CQsI",
        "title": "Fault Kinematic Analysis and Change in Late Mesozoic Tectonic Stress Regimes in the Peripheral Zones of the Ordos Basin, North China",
        "abstract": "Based on detailed field observations and measurements of fault geometry, kinematics and activity phases along the southwestern boundary zone, the central W-E fault zone, the eastern boundary zone and the northeastern area of the Ordos Basin, and according to striation superimposition relationship on fault plane and regional tectonic events, this paper established late Mesozoic stress directions, stress regimes and their evolution sequence, and proposed a 4-stage tectonic evolution model with tectonic stress regimes changed alternately between extension and compression. The Basin was under extensional stress environment during the Early-Middle Jurassic, with the extension oriented in N-S to NNE-SSW. The tectonic stress regime had changed to multi-directional (W-E, NW-SE, NE-SW) compression during the period from the latest Middle Jurassic to late Jurassic and the peripheral zones of the Ordos Basin submitted to multi-directional shortening deformation. The stress regime changed again to extension during the Early Cretaceous, with the orientations of extension being NW-SE, W-E and NE-SW. It is followed from the latest Early Cretaceous to late Cretaceous by NW-SE compression. The stress field evolution and the changes in stress regimes in the peripheral zones of the Ordos Basin during the late Mesozoic not only recorded far-field effects produced by different inter-plate convergences, but also reflected changes in deep-seated thermal-tectonic regimes beneath the Ordos Basin, which caused the proto basin to have been significantly reformed.",
        "keywords": [
            "late Mesozoic",
            "fault kinematics",
            "tectonic stress field",
            "Ordos Basin",
            "stress regime"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, "
            },
            {
                "name": "LIAO Changzhen",
                "org": " Earth Science and Resource College, China Geoscience University, Beijing, 3"
            },
            {
                "name": "HU Bo",
                "org": " 1) Department of Earth Science, Nanjing University, "
            }
        ],
        "venue": "Acta Geologica Sinica",
        "year": 2006
    },
    "Lf3ZGjOE": {
        "id": "Lf3ZGjOE",
        "title": "Study on reliability and unidimension of the Fine Motor Function Measure Scale for children with cerebral palsy",
        "abstract": "Objective To analyze unidimension,internal reliability and external reliability of the Fine Motor Function Measure Scale (FMFM)for Children with Cerebral Palsy.Methods 696 children with cerebral palsy participated in the study. 481 males(69.1%)and 215 females,the average age was 30.0 months(SD:25.9months),ranged from 2 to 183 months;Types of CP in the children were spastic quadriplegia(n=239,34.3%),spastic diplegia(n=212,30.4%),spastic hemiplegia(n=185,26.6%),athetoid(n=30,4.3%),dystonic(n=21,3.0%),ataxic(n=9,1.3%).The 86 test items formed FMFM sampling scale. All samples were measured by FMFM sampling scale at least once.86 test items of FMFM sampling scale and 696 samples were analyzed by Rasch analysis using the partial credit model(PCM). Unidimension of scale was determined by item misfit criterion(FITI), and the FITI was set as mean-square values (MnSq) from 0.6 to 1.4, At the same time ultimate selected items of the FMFM were determined.Then test-free person measurement and sample-free item calibration of these items components of FMFM were analyzed. The first 23 samples were included for test-retest reliability study with a interval of 1 to 7 days. 49 samples were selected for interscorer reliability analysis.Results After three screenings, 25 items were deleted from 86 items of FMFM sampling scale. Among the remained 61 items, the misfit items were 3, less than 5% of all, suggesting that the majority items of this measure were good in unidimension, The mean standard error of item difficulty measuring was 0.09 (range 0.06-0.15), and the reliability of items was 1.00, showing that these items had good reliability. The item separation value was 38.09, showing that these items had good stratification of difficulty.The mean standard error of the sample ability measure was 0.30 (range 0.21-1.05). The reliability of samples was 0.99, showing that the FMFM had good reliability. The item separation value was 9.13, showing that the FMFM had good stratification of difficulty. finally formal FMFM Scale of 61 items was composed. At the same time the difficulty order and criterion of the ultimate selected item were determined. Correlations between sample ability scores of different item conditions were analyzed and results indicated that FMFM had good test-free person measurement, The Pearson correlation between sample ability scores under different item conditions was very high(r=0.976-0.995). Correlations between items difficulty values of different sample conditions were also analyzed and results confirmed that FMFM had good sample-free item calibration. The Pearson correlation between item difficulty under three sample conditions was very high(r=0.993-0.998). FMFM had good test-retest reliability (ICC=0.989 3,95%CI:0.975 3-0.995 4)as well as good interscorer reliability(ICC=0.996 1,95%CI:0.993 2-0.997 8).Conclusions FMFM had excellent unidimension,internal reliability and external reliability,which would lay good foundation for future usage of FMFM. Further studies about validity and responsiveness of FMFM are needed.",
        "keywords": [
            "Assessment",
            "Fine motor",
            "Reliability",
            "Function",
            "Unidimension"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Rehabilitation Center of Children's Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": "Rehabilitation Center of Children's Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": "Rehabilitation Center of Children's Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "SU Yi",
                "org": "Rehabilitation Center of Children's Hospital of Fudan University, Shanghai ,China"
            },
            {
                "name": "ZHANG Jian-ping",
                "org": "Rehabilitation Center of Children's Hospital of Fudan University, Shanghai ,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Pediatrics",
        "year": 2008
    },
    "vgK4hY3L": {
        "id": "vgK4hY3L",
        "title": "Characteristics of chitin synthase (CHS) gene and its function in polyspermy blocking in the blood clam Tegillarca granosa",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Yu Han",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Wei Shi",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Cheng Guo",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Xinguo Zhao",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Saixi Liu",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Yichen Wang",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Wenhao Su",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Shanjie Zha",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            },
            {
                "name": "Hongxi Wu",
                "org": "2Zhejiang Mariculture Research Institute, 325005 Wenzhou, P.R. China"
            },
            {
                "name": "Xueliang Chai",
                "org": "2Zhejiang Mariculture Research Institute, 325005 Wenzhou, P.R. China"
            },
            {
                "name": "Guangxu Liu",
                "org": "1College of Animal Sciences, Zhejiang University, 310058 Hangzhou, P.R. China"
            }
        ],
        "venue": "Journal of Molluscan Studies",
        "year": 2016
    },
    "C7vYVJMZ": {
        "id": "C7vYVJMZ",
        "title": "Acupuncture Treatment of Fine Motor Dysfunction in 61 Cerebral Palsy Children",
        "abstract": "Objective To investigate the curative effect of acupuncture on fine motor dysfunction in cerebral palsy children.Methods Sixty-one sick children were treated by point injection as primary therapy plus occupational therapy.The curative effect was evaluated using the Fine Motor Function Measure.Results The score increased in 52 of the 61 sick children(85.3%) after one course of treatment,in 37 of the 40 sick children(92.5%) after two course of treatment and in all of the 23 sick children after three course of treatment.Statistical analysis showed all P<0.01.Conclusion Acupuncture plus occupational therapy has exactly a marked effect on fine motor dysfunction in cerebral palsy children.",
        "keywords": [
            "Acupuncture",
            "Point injection",
            "The Fine Motor Function Measure"
        ],
        "authors": [
            {
                "name": "BO Huai-di",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            },
            {
                "name": "LI Hui",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            },
            {
                "name": "SHI Wei",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            },
            {
                "name": "YANG Hong",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            },
            {
                "name": "WANG Su-juan",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            },
            {
                "name": "SHI Xiao-juan",
                "org": ".Rehabilitation Center,Children's Hospital Affiliated to Fudan University,Shanghai ,China"
            }
        ],
        "venue": "Shanghai Journal of Acupuncture and Moxibustion",
        "year": 2007
    },
    "ODPR8OQ9": {
        "id": "ODPR8OQ9",
        "title": "Appraisement of Water Resource Security in Manasi River Basin by Analytic Hierarchy Process and Fuzzy Comprehensive Evaluation",
        "abstract": "Based on the land use and water resource database and the statistic data about nature, economy and society situation, this paper synthetically appraised the water resource security in Manasi River Basin of Xinjiang according to 20 evaluation indices by analytic hierarchy process (AHP) and fuzzy comprehensive evaluation. The results showed that the water resource in Manasi River Basin was unsafe, with the membership degree was 0.4699 and the integrated evaluation score was 0.5291; the ecology security was at a basically safe level and water supply-demand was relatively safe; water quantity and socio-economy was unsafe. To ensure the water resource security in Manasi River Basin, it is suggested to accelerate the native economic-technological development, enhance the utilizing efficiency and the general management of water resource, control the population growth, and harmonize the water use of upstream-downstream and headstream-mainstream.",
        "keywords": [
            "analytic hierarchy process (AHP)",
            "Manasi River Basin in Xinjiang",
            "security",
            "fuzzy comprehensive evaluation",
            "assessment"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi , China;Graduate University of Chinese Academy of Sciences, Beijing , China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi , China"
            },
            {
                "name": "QIAO Mu",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi , China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi , China;Graduate University of Chinese Academy of Sciences, Beijing , China"
            }
        ],
        "venue": "Journal of Desert Research",
        "year": 2010
    },
    "OdIvNt5Q": {
        "id": "OdIvNt5Q",
        "title": "Effects of dialysate sodium concentration on blood pressure and heart function in uremic patients",
        "abstract": "Objective:To investigate the effects and safety of relatively low sodium dialysate in uremic patients. Methodology:One hundred and twenty uremic patients with hypertension were randomly divided into A and B group.In A group,patients were treated with low sodium dialysate hemodialysis(sodium concentration 135 mmol/L) for 8 weeks.In B group,patients were treated with common sodium dialysate hemodialysis(sodium concentration 142 mmol/L) for 8 weeks.The blood pressure,body mass,body mass index,serum urea nitrogen and creatinine,Kt/V and left ventricular ejection fraction(LVEF) were compared between two groups before and after eight-week treatment.The safety of low sodium dialysate hemodialysis was also evaluated by analysing dialysis adverse reactions between two groups. Results:Clinical data of two groups had no statistical difference before treatment.However,after 8 weeks treatment for A group patients,the blood pressure and body mass were decreased marketly,and their LVEF was improved significantly.Other indexes in A group and all indexes in B group had no statistical changes when compared with that before the treatment.Patients of A group had higher incidence rate of intradialysis hypotension and dialysis disequilibrium symptom when compared with B group,and no statistical difference was found in other adverse reactions between two groups. Conclusion:Relatively low sodium dialysate hemodialysis is valid to eliminate water-sodium retention,decrease blood pressure and improve cardiac function in uremic patients.But it may increase the incidence of intradialysis hypotension and dialysis disequilibrium symptom.",
        "keywords": [
            "blood purification uremia hypertension low sodium dialysate water-sodium retention"
        ],
        "authors": [
            {
                "name": "XIA Yun-feng",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "MA Jian-chao",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "YE Xi-lan",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "HE Chao-sheng",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            },
            {
                "name": "LIANG Xin-ling",
                "org": " Department of Nephology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,GuangZhou ,China"
            }
        ],
        "venue": "Chinese Journal of Nephrology,Dialysis & Transplantation",
        "year": 2009
    },
    "iO6tzKnk": {
        "id": "iO6tzKnk",
        "title": "Assessment of equation for glomerular filtration rate estimation based on serum creatine and cystatin C in chronic kidney disease of old patients",
        "abstract": "【Objectives】To evaluate the four equation for glomerular filtration rate estimation based on serum creatine in chronic kidney disease of old patients,and to develop equation for glomerular filtration rate estimation base on serum cystatin C (cysC). 【Methods】267 old inpatients from January 2008 to April 2009 were recruited in the study.(114 male/153 female, age >50 years). Serum cysC was determined by particle-enhanced turbidimetric immunoassay (PETIA), tGFR was estimated using the renal dynamic imaging method (modified Gate's method) with 99mTc-diethylene triamine pentaacetic acid (99mTc-DTPA). Equation for glomerular filtration rate (eGFR) estimation based on serum cystatin C was calculated by multiple regression. Compared with glomerular filtration rate estimated simultaneously using four methods: Cockcroft-Gault method (eGFR1); Modification of Diet in Renal Disease (MDRD) study equation (eGFR2); the modified abbreviated MDRD equation (eGFR3); the modified abbreviated MDRD equation based on demography data of chinese. To evaluate the four equation for glomerular filtration rate estimation based on erum cystatin C in chronic kidney disease of old patients. 【Results】eGFR1, eGFR2, eGFR3, eGFR4, eGFR showed positive correlation with tGFR, the correlation coefficient are 0.74、0.74、0.47、0.75、0.68, respectively, intraclass correlation coefficient are 0.80, 0.74, 0.30, 0.79, 0.65(P<0.001), linear regression equation for glomerular filtration rate estimation based on serum cystatin C is that eGFR=76.75-1.03 × cystatin C -0.59 × age+ 0.23×Alb (cystatin C: mg/L, age: year,Alb: g/L),Bland-Altman regression analysis showed that deviation, precision and accuracy of eGFR1、eGFR4 are better than eGFR2、eGFR3 and eGFR. For eGFR4, the corresponding accuracy rose to 29.4.8%, 39.43% and 64.4%, respectively. 【Conclusions】The modified abbreviated MDRD equation according to demography data of chinese was better than the others,the deviation was tiny, the precision and accuracy were much higher than the others. Our results indicated that the GFR estimation based on serum cystatin C was not better than the modified abbreviated MDRD equation based on demography data of chinese in our patient group .",
        "keywords": [
            "GFR",
            "cystatin C",
            "chronic kidney disease",
            "old patients"
        ],
        "authors": [
            {
                "name": "YE Zhiming",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "LIANG Xinling",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "HE Zhaosheng",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "LIU Shuangxin",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "LI Zhilian",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "FENG Zhonglin",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            },
            {
                "name": "LI Ruizhao",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong , P.R.China"
            }
        ],
        "venue": "China Journal of Modern Medicine",
        "year": 2009
    },
    "FRTCMJo9": {
        "id": "FRTCMJo9",
        "title": "Integration of mixed-mode chromatography and molecular imprinting technology for double recognition and selective separation of proteins",
        "abstract": "Abstract   Adsorption selectivity is one of the most important parameters for chromatography. As a promising technology for protein purification, mixed-mode chromatography (MMC) has unique advantages; however, its selectivity needs to be improved further. In this study, one strategy for improving selectivity was tested. We combined MMC with molecular imprinting technology (MIT) to gain double-recognition capabilities. Molecularly imprinted polymer (MIP) enabled the enhancement of the selectivity of MMC. Cross-linked 4% agarose beads (4FF) with tryptamine (Try) as ligands were used to prepare the double-recognition resin (4FF-Try/MIPs), with bovine serum albumin (BSA) as the imprinting template protein. After removing the template protein from the imprinted layer, 3D cavities with double-recognition abilities toward BSA were obtained, owing to the combination of hydrophobic interaction and molecularly imprinted spatial matched cavities. The static and dynamic adsorption behaviors of BSA, bovine immunoglobulin G (bIgG), and bovine hemoglobin (BHb) on resins were investigated. The results showed 4FF-Try/MIPs retained the typical adsorption properties of pH dependence and salt tolerance of MMC. High and similar dynamic binding capacities for BSA were obtained for both 4FF-Try and 4FF-Try/MIPs. However, 4FF-Try/MIPs showed lower dynamic binding capacity for the competitive impurity bIgG. When 4FF-Try/MIPs was used to separate BSA from bovine serum, the purity reached 75.1%, which was higher than 4FF-Try by ∼20%. We conclude that MIT could be applied to enhance selectivity of MMC with double recognition capabilities, and this might be a straightforward strategy for improving selectivity in other modes of chromatography.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318001, China"
            },
            {
                "name": "Siqi Zhang",
                "org": "School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318001, China"
            },
            {
                "name": "Kai-Bin Li",
                "org": "School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318001, China"
            },
            {
                "name": "Wen-Ping Jia",
                "org": "School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318001, China"
            },
            {
                "name": "Deman Han",
                "org": "School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 318001, China"
            }
        ],
        "venue": "Separation and Purification Technology",
        "year": 2018
    },
    "aDWDwP8a": {
        "id": "aDWDwP8a",
        "title": "Clinical Study on \"Tianqi Injection\" in Retarding Renal Fibrosis of Chronic Renal Failre",
        "abstract": "Objective To obseve the clinical effects of \"Tianqi Injection\" in retarding renal fibrosis of chronic renal failure(CRF) and its possible mechanism.Methods:70 patients with CRF were randomized into two groups: treatment group in 35 cases were treated by Tanqi Injection and control group in which 35 cases treated by SenAn Injection,the therapeutic period is a month.Symptom score,Laminin,Collegen IV,renal function,blood lipid, endotheliolysin,interleukin-8,side effects were measured before and after treatment.Results:The total effective rate was 71.43% in treatment group and 48.57% in control group,by contrasting the two groups there was a remarkable discrepancy(P<0.01);Clinical Symptom,renal fibrosis,renal function,blood lipid,improved obviously in control group(P<0.05 or P<0.01),and has marked curative effect in contrast with control group(P<0.05 or P<0.01),endotheliolysin and interleukin-8 decreaded obviously(P<0.01),no side effects were found.Conclusion:It is revealed that Tianqi Injection can retard renal fibrosiss of chronic renalfailre by adjusting blood lipid and decreading endotheliolysin and interleukin-8.",
        "keywords": [
            "renal fibrosis",
            "chronic renal failure",
            "Tianqi Injection"
        ],
        "authors": [
            {
                "name": "Wu Jinyu",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            },
            {
                "name": "Shi Wei",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            },
            {
                "name": "Huang Xuexia",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            },
            {
                "name": "Tang Nong",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            },
            {
                "name": "Liang Jingsong",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            },
            {
                "name": "Xiang Caichun",
                "org": "The First Affiliated Hospital of Guangxi College of TCM,Nanning ,GuangXi,China"
            }
        ],
        "venue": "Liaoning Journal of Traditional Chinese Medicine",
        "year": 2006
    },
    "vSoQxBfi": {
        "id": "vSoQxBfi",
        "title": "Anthropogenic Noise Aggravates the Toxicity of Cadmium on Some Physiological Characteristics of the Blood Clam Tegillarca granosa .",
        "abstract": "Widespread applications of cadmium (Cd) in various products have caused Cd contamination in marine ecosystems. Meanwhile, human activities in the ocean have also generated an increasing amount of noise in recent decades. Although anthropogenic noise and Cd contaminants could be present simultaneously in marine environments, the physiological responses of marine bivalve mollusks upon coexposure to anthropogenic noise and toxic metal contaminants, including Cd remain unclear. Therefore, the combined effects of anthropogenic noise and Cd on the physiological characteristics of the blood clam  were investigated in this study. The results showed that 10 days of coexposure to anthropogenic noise and Cd can enhance adverse impacts on metabolic processes, as indicated by the clearance rate, respiration rate, ammonium excretion rate, and O:N ratio of . In addition, both the ATP content, ATP synthase activity and genes encoding important enzymes in ATP synthesis significantly declined after coexposures to anthropogenic noise and Cd, which have resulted from reduced feeding activity and respiration. Furthermore, the expressions of neurotransmitter-related genes (MAO, AChE, and mAChR3) were all significantly down-regulated after coexposure to anthropogenic noise and Cd, which suggests an enhanced neurotoxicity under coexposure. In conclusion, our study demonstrated that anthropogenic noise and Cd would have synergetic effects on the feeding activity, metabolism, and ATP synthesis of , which may be due to the add-on of stress responses and neurotransmitter disturbances.",
        "keywords": [
            "Tegillarca granosa",
            "anthropogenic noise",
            "cadmium",
            "neurotoxic",
            "physiological characteristics"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Xiaofan Guan",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Jiahuan Rong",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Xueying Du",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Yu Tang",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, China."
            }
        ],
        "venue": "Frontiers in physiology",
        "year": 2019
    },
    "GqshtuFm": {
        "id": "GqshtuFm",
        "title": "Analysis of very fast transient overvoltages (VFTO) from onsite measurements on 800 kV GIS",
        "abstract": "In IEC 60071-1 and 62271-102, there is neither standard voltage shape nor standard peak value for very fast transient overvoltages (VFTO). Previous work by other researchers had classified VFTO into two types. A new type was identified in this paper based on an onsite test on a commercially-operated 800 kV GIS. Disconnectors were opened/closed under real operation conditions. Characteristics of the new VFTO type were analyzed, including times of the arc restrikes between the contacts of the disconnectors, trapped charge, damping time constant, magnitude, rise rate, and oscillating frequency. The results of this paper are expected to be of help for the completion of standards on VFTO.",
        "keywords": [
            "transients",
            "very fast transient overvoltages",
            "arcs (electric)",
            "digital measurements",
            "switching transients",
            "voltage measurement",
            "gas insulated switchgear",
            "disconnector switching",
            "gas insulated substations",
            "ehv substations",
            "iec standards",
            "overvoltage",
            "voltage 800 kv"
        ],
        "authors": [
            {
                "name": "Yunge Li",
                "org": "Shaanxi Electric Power Research Institute(Shaanxi Electric Power Research Institute),Xi'an,China"
            },
            {
                "name": "Yong Shang",
                "org": "Shaanxi Electric Power Corporation(Shaanxi Electric Power Company,Shaanxi Electric Power Corporation),Xi'an,China"
            },
            {
                "name": "Lin Zhang",
                "org": "Shaanxi Electric Power Corporation(Shaanxi Electric Power Company,Shaanxi Electric Power Corporation),Xi'an,China"
            },
            {
                "name": "Rong Shi",
                "org": "Shaanxi Electric Power Corporation(Shaanxi Electric Power Company,Shaanxi Electric Power Corporation),Xi'an,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Dielectrics and Electrical Insulation, IEEE Transactions",
        "year": 2012
    },
    "BRp9ng0n": {
        "id": "BRp9ng0n",
        "title": "A colorimetric/fluorescence dual-channel probe for highly discriminating detection of cysteine.",
        "abstract": "In this work, a novel fluorescence (FL) probe for selective and sensitive detection of Cys with colorimetric and FL dual signal changes was reported. The probe was synthesized by two step of sulfonamide reaction coupling between a sulfonyl benzoxadiazole (SBD) dye and dansyl chloride linked with rigid piperazine group. The probe showed a specific off-on response to Cys in aqueous solution with nanomolar LOD, and without interference by a range of amino acids and several competing analytes. Upon addition of Cys, the probe will undergo sequential substitution and intramolecular rearrangement reactions, yielding a 4-amino SBD derivative, which results in generation of strong yellow fluorescence emission at 575 nm accompanied by a two-step red shift in the absorption spectral. Moreover, it can be used for imaging of endogenous Cys in living cells.",
        "keywords": [
            "Biothiols",
            "Colorimetric",
            "Fluorescence probe",
            "Image analysis"
        ],
        "authors": [
            {
                "name": "Kai-Bin Li",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Wang-Bo Qu",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "De-Man Han",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China. Electronic address: hdmtzc@126.com."
            },
            {
                "name": "Siqi Zhang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Cai-Xia Chen",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            },
            {
                "name": "Xiu-Xia Liang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang 318000, PR China."
            }
        ],
        "venue": "Talanta",
        "year": 2019
    },
    "TtkMc8Wf": {
        "id": "TtkMc8Wf",
        "title": "Design, synthesis, and biological evaluation of deuterated phenylpropionic acid derivatives as potent and long-acting free fatty acid receptor 1 agonists.",
        "abstract": "The free fatty acid receptor 1 (FFA1) is a potential target due to its function in enhancement of glucose-stimulated insulin secretion. Takeda's compound 1 has robustly in vitro activity for FFA1, but it has been suffered from poor pharmacokinetic (PK) profiles because the phenylpropanoic acid is vulnerable to beta-oxidation. To identify orally available agonists, we tried to interdict the metabolically labile group by incorporating two deuterium atoms at the alpha-position of phenylpropionic acid. Interestingly, the differences of physicochemical properties between hydrogen and deuterium are quite small, but there are many differences in the structure-activity relationship between phenylpropionic acid series and present deuterated series. Further optimizations of deuterated series led to the discovery of compound 18, which exhibited a superior balance in terms of in vitro activity, lipophilicity, and solubility. Better still, compound 18 revealed a lower clearance (CL = 0.44 L/h/kg), higher maximum concentration (C-max = 7584.2 7 mu g/L), and longer half-life (T-1/2 = 4.16 h), resulting in a >23-fold exposure than compound 1. In subsequent in vivo pharmacodynamic studies, compound 18 showed a robustly glucose-lowering effect in rodent without the risk of hypoglycemia. (C) 2017 Elsevier Inc. All rights reserved.",
        "keywords": [
            "Deuteration",
            "Diabetes",
            "Free fatty acid receptor",
            "Pharmacokinetic profiles",
            "Hypoglycemia"
        ],
        "authors": [
            {
                "name": "Zheng Li",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Chunxia Liu",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Xue Xu",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Huilan Li",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Yuxuan Dai",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Xingguang Cai",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Wenlong Huang",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            },
            {
                "name": "Hai Qian",
                "org": "China Pharmaceut Univ, State Key Lab Nat Med, Ctr Drug Discovery, 24 Tongjiaxiang, Nanjing 210009, Jiangsu, Peoples R China"
            }
        ],
        "venue": "BIOORGANIC CHEMISTRY",
        "year": 2017
    },
    "ueflgdR6": {
        "id": "ueflgdR6",
        "title": "Design and Implementation of the Asynchronous Sub-Word Parallel MAC Unit",
        "abstract": "The problems such as clock skew and high power consumption may exist in synchronous integrated circuit design,which can be well solved in asynchronous design.A 32-bit asynchronous sub-word parallel MAC unit in adopting the asynchronous integrated circuit design method is presented in this paper.And it is implemented in the 0.18μm process.The MAC unit we design supports various sub-word parallel models using a special partial product decode circuit.It is suitable for multimedia processing.The test results indicate the performance and power consumption of this asynchronous MAC unit are superior to the synchronous counterpart.",
        "keywords": [
            "sub-word parallel",
            "asynchronous",
            "MAC"
        ],
        "authors": [
            {
                "name": "WANG You-rui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG Lei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "DAI Kui",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            },
            {
                "name": "WANG Zhi-ying",
                "org": "School of Computer Science,National University of Defense Technology,Changsha ,China"
            }
        ],
        "venue": "Computer Engineering & Science",
        "year": 2009
    },
    "AoUYxymV": {
        "id": "AoUYxymV",
        "title": "An Embedded Player Solution for Real-time Network Transmission MP3 Date Stream",
        "abstract": "This paper introduces the selection of the network interface scheme and MP3 decoding scheme,advances an embedded network MP3 real-time player,and introduces the design of the embedded player system and the application of MP3 decoder STA015.",
        "keywords": [
            "STA015",
            "TCP/IP",
            "MP3 decoding"
        ],
        "authors": [
            {
                "name": "CHEN Chang",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2007
    },
    "FeXFVhhI": {
        "id": "FeXFVhhI",
        "title": "Nonlinear Characteristics of Climatic Factors in Oasis of Arid Northwest China: A case study of Shihezi, Xinjiang",
        "abstract": "Based on annual mean temperature and precipitation data during 1959—2006, the characteristics of climatic factors in Shihezi, a typical oasis in arid areas of northwest China, was researched through Morlet wavelet analysis, fractal analysis and R/S analysis. The results showed that the climatic variation of Shihezi presented a complex nonlinearity with waved, fractal and chaotic characteristics. The primary annual precipitation variation periods were 5, 8, 14, and 20 years, but only periods of 5 and 8 years were significant at P>0.05. The primary periods of annual mean temperature variation were 4, 7 and 11 years, and all these periods were significant at P>0.05. The correlative dimensions of annual mean temperature and annual precipitation series were 4.51 and 3.21 respectively, both were non-integral, indicating the fractal and chaotic variation processes of climatic factors. The embedding dimensions of annual mean temperature and annual precipitation were 7 and 6 respectively, which indicated that it needed 5～7 and 4～6 independent variables respectively to build systemic dynamic models. Based on the R/S analysis of annual mean temperature series (1992—2006) and annual precipitation series (1987—2006) of Shihezi, the Hurst exponents indicated that the annual mean temperature would keep an increasing trend in the coming 15 years after 2006, while the annual precipitation would keep a slightly decreasing trend in the coming 20 years.",
        "keywords": [
            "Shihezi",
            "climate factor",
            "arid areas of northwest China",
            "nonlinear"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi ,China;Graduate Uuniversity of Chinese Academy of Sciences, Beijing , China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi ,China;Graduate Uuniversity of Chinese Academy of Sciences, Beijing , China"
            },
            {
                "name": "ZHANG Qing-qing",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi ,China;Graduate Uuniversity of Chinese Academy of Sciences, Beijing , China"
            }
        ],
        "venue": "Journal of Desert Research",
        "year": 2010
    },
    "NSQgm1OJ": {
        "id": "NSQgm1OJ",
        "title": "Fabrication of 2×2 tapered multimode interference coupler",
        "abstract": "A new multimode interference (MMI) coupler with a parabolically tapered width has been designed using silicon on insulator (SOI) technology. This structure allows the gap between the access waveguides to increase while maintaining a short device length. Uniform power distribution in the output ports was observed. The uniformity is less than 0.8 dB, while the length of the device is much shorter than that of the straight MMI coupler.",
        "keywords": [
            "extinction ratio",
            "light interference",
            "fabrication",
            "optical switches",
            "silicon on insulator"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Zhongli Liu",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Xioafeng Zhang",
                "org": "Institute of Semiconductors Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Electronics Letters",
        "year": 2000
    },
    "cG9nb3Y0": {
        "id": "cG9nb3Y0",
        "title": "Correlation of soil properties and fruit size of Callgonum mongolicum and related species: Correlation of soil properties and fruit size of Callgonum mongolicum and related species",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "borong pan",
                "org": ""
            },
            {
                "name": "habibullo shomurodov",
                "org": ""
            }
        ],
        "venue": "Journal of Arid Land",
        "year": 2012
    },
    "aHqx8goz": {
        "id": "aHqx8goz",
        "title": "Intra-individual variation and transcribed pseudogenes in the ribosomal ITS1-5.8S-ITS2 rDNA of Paraplagusia japonica (Pleuronectiformes: Cynoglossidae).",
        "abstract": "The eukaryotic ribosomal DNA (rDNA) cluster consists of multiple copies of three genes (18S, 5.8S, and 28S rDNA) and two internal transcribed spacers (ITS1 and ITS2). Typically, rDNA is thought to be evolved in a strict concerted evolution pattern, in which show little or even no variations within species, while sequence diversity between species or higher taxa. However, in the present study, we reported a high level of intra-individual polymorphism of ITS1-5.8S-ITS2 rDNA in the genome of Paraplagusia japonica (Pleuronectiformes: Cynoglossidae), suggesting it conformed a non-concerted evolutionary pattern. Three divergent type sequences (Type A, B, and C) differing in length, GC content, secondary structure stability and minimum free energy coexisted in the genome of each studied individual. According to the particular features of ribosomal pseudogenes, Type B and Type C sequences were postulated as pseudogenes. Expression analyses gave clear evidence that both the functional gene and pseudogenes were abundantly transcribed, indicating expression is not an applicable criterion for identifying ribosomal pseudogenes. These findings will enrich useful data for the studies on rDNA evolution in flatfishes, as well as provide fresh insight on the transcribed ribosomal pseudogenes and further consideration of the definition of ribosomal pseudogene.",
        "keywords": [
            "Expression",
            "Non-concerted evolution",
            "RT-PCR",
            "Ribosomal RNA",
            "Transcribed pseudogene"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": "National Engineering Laboratory of Marine Germplasm Resources Exploration and Utilization, Zhejiang Ocean University, 316022, Zhoushan, China; National Engineering Research Center for Facilitated Marine Aquaculture, Marine Science and Technology College, Zhejiang Ocean University, 316022, Zhoushan, China. Electronic address: gongli1027@163.com."
            },
            {
                "name": "Hairong Luo",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510000, China; South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangzhou, 510000, China."
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510000, China; South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangzhou, 510000, China."
            },
            {
                "name": "Min Yang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, 510000, China; South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center, Guangzhou, 510000, China."
            }
        ],
        "venue": "Biochemical and biophysical research communications",
        "year": 2019
    },
    "JnAH9Lws": {
        "id": "JnAH9Lws",
        "title": "Original article: INFLUENCE OF ENVIRONMENTAL VARIABILITY ON PHYLOGENETIC DIVERSITY AND TRAIT DIVERSITY WITHIN CALLIGONUM COMMUNITIES",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "jiancheng wang",
                "org": ""
            },
            {
                "name": "honglan yang",
                "org": ""
            },
            {
                "name": "xiyong wang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "borong pan",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2014
    },
    "JYFDCYYz": {
        "id": "JYFDCYYz",
        "title": "Neurotoxic impact of acute TiO 2 nanoparticle exposure on a benthic marine bivalve mollusk, Tegillarca granosa.",
        "abstract": "The release of nanoparticles (NPs) into the ocean inevitably poses a threat to marine organisms. However, to date, the neurotoxic effects of NPs remains poorly understood in marine bivalve species. Therefore, in order to gain a better understanding of the physiological effects of NPs, the impact of acute (96 h) TiO NP exposure on the in vivo concentrations of three major neurotransmitters, the activity of AChE, and the expression of neurotransmitter-related genes was investigated in the blood clam, Tegillarca granosa. The obtained results showed that the in vivo concentrations of the three tested neurotransmitters (DA, GABA, and ACh) were significantly increased when exposed to relatively high doses of TiO NPs (1 mg/L for DA and 10 mg/L for ACh and GABA). Additionally, clams exposed to seawater contaminated with TiO NP had significantly lower AChE activity. In addition, the expression of genes encoding modulatory enzymes (AChE, GABAT, and MAO) and receptors (mAChR3, GABAD, and DRD3) for the neurotransmitters tested were all significantly down-regulated after TiO NP exposure. Therefore, this study has demonstrated the evident neurotoxic impact of TiO NPs in T. granosa, which may have significant consequences for a number of the organism's physiological processes.",
        "keywords": [
            "Blood clam",
            "Gene expression",
            "Nanoparticle",
            "Neurotoxicity",
            "Neurotransmitters",
            "Titanium dioxide"
        ],
        "authors": [
            {
                "name": "Xiaofan Guan",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Wei Shi",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Jiahuan Rong",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Science, Zhejiang University, Hangzhou, 310058, China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "Aquatic toxicology (Amsterdam, Netherlands)",
        "year": 2018
    },
    "6cWIxwIW": {
        "id": "6cWIxwIW",
        "title": "Structural deformation of the Gaochuan Terrane in the western Dabashan tectonic belt, China and its significance",
        "abstract": "The Mianlue tectonic belt, trending from west to east, was regarded as the suture zone between the North China and South China continent during the Indochina movement and it is very important for the formation and evolution of China continent. But the extension of the belt eastwards and westwards hasn′t been got an affirmative conclusion. Especially, from east Mianxian of Shaanxi Province to Suizhou of Hubei Province, there have been no any evidences about the suture zone. In previous important papers, it is regarded the Mianlue suture zone turns to south from Lianghekou town of Ningshan County, then it goes through the Gaochuan slab and stretched along the arc belt of Dabashan to Suizhou of Hubei Province eastwards. In our paper, it is proped that the Gaochuan slab is an allochthonous geological terrane and named as the Gaochuan Terrane. The Gaochuan Terrane is a dextral strike slipping system composed of some strike slipping faults trending in nearly south to north and some strike slipping shearing folds with axes trending in nearly south to north. It is suggested that the terreane was wedged into the Dabashan belt from original the Mianlue suture zone when the Dabashan thrust belt thrust towards south. It is only a shallow geological slab of the crust under duress between the Dabashan thrust belt and the Dabashan foreland belt. The present location of the Gaochuan terrain doesn′t represent the eastern extension of the Mian- lue suture zone. Therefore, the arc Dabashan tectonic belt isn't the location of the final collision of the south and north China conti- nents.",
        "keywords": [
            "Dabashan tectonic belt",
            "Gaochuan Terrane",
            "Mianlue suture zone"
        ],
        "authors": [
            {
                "name": "HU Jian-min",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "DONG Shu-wen",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "MENG Qing-ren",
                "org": "Institute of Geology and Geophysics Chinese Academy of Sciences(Chinese Academy of Sciences),Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "Hong Chen",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            },
            {
                "name": "WU Guo-li",
                "org": "Chinese Academy of Geological Sciences(Chinese Academy of Geological Sciences,Chinese Academy of Geological Sci.,Chinese Acad. of Geological Sciences),Beijing,China"
            }
        ],
        "venue": "Geological Bulletin of China",
        "year": 2008
    },
    "ufxav02L": {
        "id": "ufxav02L",
        "title": "Electrical transport properties of Cu2Se dispersed and Na-doped Bi2Ba2Co2Oy thermoelectric composites",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Senlin Leng",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Hongzhang Song",
                "org": ""
            }
        ],
        "venue": "international conference on energy environment",
        "year": 2018
    },
    "4GiCy6vt": {
        "id": "4GiCy6vt",
        "title": "11R-VIVIT inhibits the expression of urokinase-type plasminogen activator receptor in podocytes]",
        "abstract": "To observe the effect of 11R-VIVIT on lipopolysaccharide (LPS)-induced expression of urokinase-type plasminogen activator receptor (uPAR) in podocytes.A LPS-induced proteinuria mouse model and in vitro cultured podocytes treated with LPS were both divided into control group, LPS group and LPS+11 R-VIVIT group. The mRNA and protein expressions of uPAR in mouse kidney tissues and the podocytes were measured by real-time qPCR, laser scanning confocal microscopy and Western blotting.Compared with LPS group, LPS+11 R-VIVIT group showed a significantly lowered urine albumin/creatinine ratio (P<0.001) and markedly reduced mRNA and protein expressions of uPAR (PuPAR mRNA<0.001; PuPAR=0.001).11R-VIVIT can ameliorate proteinuria probably by decreasing the expression of uPAR in podocytes.",
        "keywords": [
            "urokinase-type plasminogen activator receptor",
            "podocytes",
            "11r-vivit"
        ],
        "authors": [
            {
                "name": "Ruizhao Li",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Wei Shi",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Juan Ma",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Bin Zhang",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Li Zhang",
                "org": " Graduate School, Southern Medical University, Guangzhou , China"
            },
            {
                "name": "Xinling Liang",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Yuanhan Chen",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Shuangxin Liu",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            },
            {
                "name": "Wenjian Wang",
                "org": " 1 Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical sciences, Guangzhou , China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2013
    },
    "bthSPguc": {
        "id": "bthSPguc",
        "title": "Morphologic Characteristics of Yangjiao Basalt in the Middle Taihang Mountains and Their Geological Significance",
        "abstract": "The uplift events have been recorded by the basalt around Yangjiao Town of Zuoquan County in middle Taihang Mountains since the end of Pliocene.Based on field investigation,the authors studied the morphologic characteristics of the basalt and the related topographic surface,and detected that the basalt was formed between the end of Pliocene and the beginning of Early Pleistocene.The geomorphic evolution of the middle Taihang Mountains since Late Pliocene is as follows:in Late Pliocene,this area underwent two phases of geomorphic evolution,i.e.,uplift and erosion,and this led to the formation of the \"U\" valley;at the end of Pliocene,because of the repeated and intermittent eruption of the basalt and the uplift of the geomorphic surface of the middle Taihang Mountains centered at Wujiaping Village,the basalt filled the \"U\" valley,and then the geomorphic surface of the fourth terrace was formed through erosion and accumulation;in Early Pleistocene,the geomorphic surface of the middle Taihang Mountains was uplifted so that the fourth step terrace was formed.At the end of Middle Pleistocene,the third terrace was formed;Since Late Pleistocene,two times of uplifting of the geomorphic surface took place,and hence all of the four steps of terraces came into being on the basalt.It is shown that the uplift of the middle Taihang Mountains occurred mainly between the end of Pliocene and Early Pleistocene.This cognition offers material evidence for the uplift of the middle Taihang Mountains since Late Pliocene.",
        "keywords": [
            "terrace",
            "topographic surface",
            "erosion",
            "\"U\" valley uplift",
            "Taihang Mountains",
            "basalt"
        ],
        "authors": [
            {
                "name": "GONG Ming-quan",
                "org": ") 1) Institute of Geomechanics,CAGS,Beijing "
            },
            {
                "name": "MA Yin-sheng",
                "org": ") 1) Institute of Geomechanics,CAGS,Beijing ; Key Laboratory of Neotectonic Movement and Geohazard,Ministry of Land and Resources,Beijing "
            },
            {
                "name": "ZHAO Xi-tao",
                "org": " Institute of geology and Geophysics,CAS,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": ") 1) Institute of Geomechanics,CAGS,Beijing ; Key Laboratory of Neotectonic Movement and Geohazard,Ministry of Land and Resources,Beijing "
            },
            {
                "name": "DU Jian-jun",
                "org": ") 1) Institute of Geomechanics,CAGS,Beijing ; Key Laboratory of Neotectonic Movement and Geohazard,Ministry of Land and Resources,Beijing "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2010
    },
    "h3B8mVGp": {
        "id": "h3B8mVGp",
        "title": "Complete mitochondrial genome sequences of two parasitic/commensal nemerteans, Gononemertes parasita and Nemertopsis tetraclitophila (Nemertea: Hoplonemertea).",
        "abstract": "Most nemerteans (phylum Nemertea) are free-living, but about 50 species are known to be firmly associated with other marine invertebrates. For example, Gononemertes parasita is associated with ascidians, and Nemertopsis tetraclitophila with barnacles. There are 12 complete or near-complete mitochondrial genome (mitogenome) sequences of nemerteans available in GenBank, but no mitogenomes of none free-living nemerteans have been determined so far. In the present paper complete mitogenomes of the above two parasitic/commensal nemerteans are reported.The complete mitochondrial genomes (mitogenome) of G. parasita and N. tetraclitophila were amplified by conventional and long PCR. Phylogenetic analyses of maximum likelihood (ML) and Bayesian inference (BI) were performed with both concatenated nucleotide and amino acid sequences.Complete mitogenomes of G. parasita and N. tetraclitophila are 14742 bp and 14597 bp in size, respectively, which are within the range of published Hoplonemertea mitogenomes. Their gene orders are identical to that of published Hoplonemertea mitogenomes, but different from those of Palaeo- and Heteronemertea species. All the coding genes, as well as major non-coding regions (mNCRs), are AT rich, which is especially pronounced at the third codon position. The AT/GC skew pattern of the coding strand is the same among nemertean mitogenomes, but is variable in the mNCRs. Some slight differences are found between mitogenomes of the present species and other hoplonemerteans: in G. parasita the mNCR is biased toward T and C (contrary to other hoplonemerteans) and the rrnS gene has a unique 58-bp insertion at the 5' end; in N. tetraclitophila the nad3 gene starts with the ATT codon (ATG in other hoplonemerteans). Phylogenetic analyses of the nucleotide and amino acid datasets show early divergent positions of G. parasita and N. tetraclitophila within the analyzed Distromatonemertea species, and provide strong support for the close relationship between Hoplonemertea and Heteronemertea.Gene order is highly conserved within the order Monostilifera, particularly within the Distromatonemertea, and the special lifestyle of G. parasita and N. tetraclitophila does not bring significant variations to the overall structures of their mitogenomes in comparison with free-living hoplonemerteans.",
        "keywords": [
            "Nemertea",
            " Gononemertes parasita",
            " Nemertopsis tetraclitophila",
            " Parasitic/Commensal",
            " Mitochondrial genome",
            " Phylogeny"
        ],
        "authors": [
            {
                "name": "Wen-Yan Sun",
                "org": "Institute of Evolution & Marine Biodiversity,Ocean University of China,Qingdao,China"
            },
            {
                "name": "Dong-Li Xu",
                "org": "Institute of Evolution & Marine Biodiversity,Ocean University of China,Qingdao,China"
            },
            {
                "name": "Hai-Xia Chen",
                "org": "Institute of Evolution & Marine Biodiversity,Ocean University of China,Qingdao,China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Marine Bio-resource Sustainable Utilization (LMB),South China Sea Institute of Oceanology, Chinese Academy of Sciences,Guangzhou,China"
            },
            {
                "name": "Per Sundberg",
                "org": "Department of Biological and Environmental Sciences,University of Gothenburg,Gothenburg,Sweden"
            },
            {
                "name": "Malin Strand",
                "org": "Swedish Species Information Centre,Swedish University of Agricultural Sciences,Uppsala,Sweden"
            },
            {
                "name": "Shi-Chun Sun",
                "org": "Institute of Evolution &amp; Marine Biodiversity, Ocean University of China, 5 Yushan Road, Qingdao 266003, China. sunsc@ouc.edu.cn."
            }
        ],
        "venue": "Parasites & vectors",
        "year": 2014
    },
    "0NbtVXNI": {
        "id": "0NbtVXNI",
        "title": "The complete mitochondrial genome of Cynoglossus puncticeps (Pleuronectiformes: Cynoglossidae).",
        "abstract": "Abstract Cynoglossus puncticeps (Soleoidei Cynoglossidae) is characterized by both eyes on the left side of the body. Here we report the mitogenome of this tonguesole for the first time, which is 17,142 bp in length, and the gene order has been reorganized. The tRNA-Gln gene translocated from the light strand (L-strand) to the heavy strand (H-strand), accompanied by tRNA-Ile gene shuffling. In addition, the putative control region translocated downstream to the position between the ND1 and the tRNA-Gln genes, leaving a 25-bp trace fragment in the original location. In addition, two tandem arrays were found: one was a 17-bp motif with 40.2 copies, and the other was 73-bp with 3.0 copies.",
        "keywords": [
            "mitogenome",
            "mottled tonguesole",
            "reorganization"
        ],
        "authors": [
            {
                "name": "Min Yang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , P.R. China and."
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Xian-Guang Miao",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2014
    },
    "eQ5l7V3h": {
        "id": "eQ5l7V3h",
        "title": "Application of flash in clinical teaching of neurosurgery",
        "abstract": "The combination of nervous system structure,form and functions has been the difficulty and key point in clinical teaching of neurosurgery.A good cartoon demonstration can solve this problem better.In order to further improve the multimedia technology and teaching means,flash courseware has been developed and applied to clinical teaching of neurosurgery in five-year program medical students of 2007.Good evaluations have been received from students and teachers as well,which not only can flash courseware interpret the difficult and key point vividly and lively,but also can contribute to integrating theory and clinical knowledge better and improve the quality of clinical teaching of neurosurgery.",
        "keywords": [
            "multimedia",
            "neurosurgery",
            "clinical teaching",
            "flash courseware"
        ],
        "authors": [
            {
                "name": "SHI Jin-long",
                "org": "Affiliated Hospital of Nantong University,Nantong ,Jiangsu,China"
            },
            {
                "name": "SHI Wei",
                "org": "Affiliated Hospital of Nantong University,Nantong ,Jiangsu,China"
            },
            {
                "name": "NI Lan-chun",
                "org": "Affiliated Hospital of Nantong University,Nantong ,Jiangsu,China"
            }
        ],
        "venue": "China Higher Medical Education",
        "year": 2011
    },
    "YsPHljZ9": {
        "id": "YsPHljZ9",
        "title": "Study of fundamental ferroresonance on neutral-grounded systems by using analytical method-criterion and elimination",
        "abstract": "The cause and the elimination of fundamental ferroresonance have been discussed by using analytical method. This phenomenon is likely to happen when the power frequency excitation characteristic of the nonlinear inductor intersects the voltage-current characteristic of the Thevenin equivalent source of the resonant circuit, or to say it another way, when the circuit resistance is larger than the critical damping value. This value is given as an analytical equation. A suppression means is then proposed. For a substation subjected to ferroresonance, a resistance is added to the busbar PT's secondary side in parallel connection, so that the resultant can be less than the critical value. This means proved effective in analyzing and suppressing ferroresonance at a 110 kV substation.",
        "keywords": [
            "EMTP",
            "Ferroresonance",
            "Inductance",
            "Nonlinear circuits",
            "Potential transformer"
        ],
        "authors": [
            {
                "name": "Yunge Li",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Zhongguo Dianji Gongcheng Xuebao/Proceedings of the Chinese Society of Electrical Engineering",
        "year": 2003
    },
    "pi0gj5Si": {
        "id": "pi0gj5Si",
        "title": "Treatment of Uremic Encephalopathy from Phlegm And Stasis",
        "abstract": "Objective: To observe the effect of hematodialysis and Chinese medicine in treatment of uremic encephalopathy to improve the quality of life of patients with end-stage uremic encephalopathy.Methods: 62 cases were enrolled and randomly divided into control and treatment groups with 31 cases in each.The control group used routine hematodialysis while the treatment group added Huayu Paidu Formula.The treatment course was 1.5 months,observing for 3 courses.BUN,Scr,HCT,TP,β2-MG and PTH were observed and compared before and after treatment.Results: In treatment group,TACurea,PCR and β2-MG were all superior to those of control group(P < 0.01),indicating Huayu Paidu Formula has obvious effect on uremic encephalopathy.Conclusion: Huayu Paidu Formula combined with hematodialysis can effectively clear the uremic toxins and improve the quality of life and dialysis adequacy.It is an effective treatment of uremia.",
        "keywords": [
            "uremic encephalopathy",
            "hematodialysis",
            "TCM therapy",
            "phlegm and stasis"
        ],
        "authors": [
            {
                "name": "ZHONG Jian",
                "org": "The First Clinical Medical School of Guangxi University of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "LI Fengyi",
                "org": "The First Clinical Medical School of Guangxi University of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "SHI Wei",
                "org": "The First Clinical Medical School of Guangxi University of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            },
            {
                "name": "TANG Nong",
                "org": "The First Clinical Medical School of Guangxi University of Traditional Chinese Medicine,Nanning ,Guangxi,China"
            }
        ],
        "venue": "Liaoning Journal of Traditional Chinese Medicine",
        "year": 2013
    },
    "GRkUQWvS": {
        "id": "GRkUQWvS",
        "title": "Properties of LUTGS crystal grown above curie temperature",
        "abstract": "",
        "keywords": [
            "domain structure",
            "lutgs crystal",
            "pyroelectric figure of merit",
            "single crystal",
            "curie temperature",
            "figure of merit",
            "hysteresis loop"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Min Wang",
                "org": ""
            },
            {
                "name": "Qingtian Gu",
                "org": ""
            },
            {
                "name": "Xun Sun",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "Ferroelectrics",
        "year": 1999
    },
    "M5n49lpC": {
        "id": "M5n49lpC",
        "title": "Mao Zedong Thought is Utopian Socialism?",
        "abstract": "Maurice Meisner is the westen Marxist and expert who study the history of CCPand Chinese Marxism.Especially,be has unique study and point of view to Mao Zedong Thought.This paper presents the author's point of view to the book,Marxism,Mao Zedong Thought and Utopia in order to understand and study Mao Zedong Thought further.",
        "keywords": [
            "Utopian Socialism",
            "Mao Zedong Thought",
            "Socialism",
            "Utopia"
        ],
        "authors": [
            {
                "name": "HAN Qiu-hong",
                "org": "College of Politics and Law,Northeast Normal University,Changchun,Jilin,"
            },
            {
                "name": "SHI Wei",
                "org": "College of Politics and Law,Northeast Normal University,Changchun,Jilin,"
            }
        ],
        "venue": "Jilin Normal University Journal(Humanities & Social Science Edition)",
        "year": 2007
    },
    "wwxdfMm6": {
        "id": "wwxdfMm6",
        "title": "Analysis of THz Electromagnetic Wave Output Character Based on High Performance 85mm Short Cavity Optical Parametric Oscillator",
        "abstract": "The THz wave output with the 85 mm F-P single cavity optical parametric oscillator based on the(MgO∶LiNbO_3) crystal was reported.The Nd∶YAG Q-switched laser with 1064 nm was used as the pump source,and the THz wave was tuned by changing the incident angle as well as the phase matching condition.THz wave frequency can be detected with the THz interferometer and the Si bolometer,or by detecting the idle light frequency.Experimental results indicate the THz wave is 0.9～3.0 THz tunable.The peak energy output is 102.5 pJ/pulse at 1.2 THz with the pump energy of 20 mJ/pulse,pulse width of 16 ns,repetition rate of 50 Hz.THz energy output was increased when a Si-prism array was introduced to decrease THz(wave's) total reflection at the interface of crystal.The THz wave beam pattern along the horizontal was measured with a metal-slit-detector.The influence of diffraction effect of the Si prism array on the THz wave beam spatial profile was discussed.",
        "keywords": [
            "optical parametric oscillater",
            "nonlinear optics",
            "THz electromagnetic wave",
            "LiNbO_3"
        ],
        "authors": [
            {
                "name": "Zhang Xianbin",
                "org": " H. Ito~21 Department of Applied Physics,Xi'an University of Technology,Xi'an 2 Photodynamics Research Center,RIKEN,Sendai,Japan"
            },
            {
                "name": "Chen Yingli",
                "org": " H. Ito~21 Department of Applied Physics,Xi'an University of Technology,Xi'an 2 Photodynamics Research Center,RIKEN,Sendai,Japan"
            },
            {
                "name": "Shi Wei",
                "org": " H. Ito~21 Department of Applied Physics,Xi'an University of Technology,Xi'an 2 Photodynamics Research Center,RIKEN,Sendai,Japan"
            }
        ],
        "venue": "Acta Optica Sinica",
        "year": 2006
    },
    "eENv8JA5": {
        "id": "eENv8JA5",
        "title": "Ca2+-channel and calmodulin play crucial roles in the fast electrical polyspermy blocking of Tegillarca granosa (Bivalvia: Arcidae)",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Cheng Guo",
                "org": "#N#        #N#        College of Animal Sciences, Zhejiang University, 310058 Hangzhou, PR China"
            },
            {
                "name": "Yu Han",
                "org": "#N#        #N#        College of Animal Sciences, Zhejiang University, 310058 Hangzhou, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "#N#        #N#        College of Animal Sciences, Zhejiang University, 310058 Hangzhou, PR China"
            },
            {
                "name": "Xinguo Zhao",
                "org": "#N#        #N#        College of Animal Sciences, Zhejiang University, 310058 Hangzhou, PR China"
            },
            {
                "name": "Shuangshuang Teng",
                "org": "#N#        #N#        Zhejiang Mariculture Research Institute, 325005 Wenzhou, PR China"
            },
            {
                "name": "Guoqiang Xiao",
                "org": "#N#        #N#        Zhejiang Mariculture Research Institute, 325005 Wenzhou, PR China"
            },
            {
                "name": "Maocang Yan",
                "org": "#N#        #N#        Zhejiang Mariculture Research Institute, 325005 Wenzhou, PR China"
            },
            {
                "name": "Xueliang Chai",
                "org": "#N#        #N#        Zhejiang Mariculture Research Institute, 325005 Wenzhou, PR China"
            },
            {
                "name": "Guangxu Liu",
                "org": "#N#        #N#        College of Animal Sciences, Zhejiang University, 310058 Hangzhou, PR China"
            }
        ],
        "venue": "Journal of Molluscan Studies",
        "year": 2017
    },
    "hGtF5e31": {
        "id": "hGtF5e31",
        "title": "The Key Technologies of and Problems Faced by the Face Identification",
        "abstract": "This paper describes the whole framework of face identification technology,probes into two key links of face identification of the pretreatment and the face detection-location,and sums up some existing key problems.",
        "keywords": [
            "face location",
            "face detection",
            "face identification"
        ],
        "authors": [
            {
                "name": "WANG Yu-jie",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2008
    },
    "K7fYx3rp": {
        "id": "K7fYx3rp",
        "title": "Impact of pre-operative uric acid on acute kidney injury after cardiac surgery in elderly patients]",
        "abstract": "To investigate the impact of pre-operative uric acid on acute kidney injury (AKI) after cardiac surgery in elderly patients.Clinical data were collected from 936 elderly patients (age ≥ 60 years) undergoing cardiac surgery with cardiopulmonary bypass in Guangdong General Hospital between January 2005 and May 2011. The baseline serum creatinine was defined as the latest serum creatinine before surgery, and AKI was diagnosed according to RIFLE criteria. Patients were divided into three groups according to the sex-specific cutoff values of serum uric acid tertiles (group A: ≤ 384.65 µmol/L in men, and ≤ 354.00 µmol/L in women; group B:384.66-476.99 µmol/L in men and 354.01-437.96 µmol/L in women; group C: ≥ 477.00 µmol/L in men and ≥ 437.97 µmol/L in women). Multivariate logistic regression analysis was used to analyze the independent risk factors for AKI.Among 936 elderly patients, 576 cases (61.5%) developed AKI. Mean uric acid concentration was higher in AKI patients than in Non-AKI patients ( (436.6 ± 119.1) µmol/L vs. (398.0 ± 107.2) µmol/L, P < 0.001). The incidence of AKI was 56.1% (175/312) in group A, 56.3% (175/311) in group B, 72.2% (226/313) in group C (P < 0.001). Multiple logistic regression analysis showed that, after adjusted for age, gender, co-morbidities(hypertension, diabetes mellitus, cerebrovascular disease, chronic obstructive pulmonary disease), previous cardiac surgery, eGFR<60 ml×min(-1) ×1.73 m(-2), heart function ≥ 3 (NYHA), positive urine protein, combination of coronary artery bypass grafting and valvular surgery, cardiopulmonary bypass operation time, aortic cross-clamping time, pre-operative angiotensin converting enzyme inhibitor or angiotensin II receptor blockers and lipid-lowering drugs use, early postoperative angiotensin converting enzyme inhibitor or angiotensin II receptor blockers, diuretics and digoxin use, post-operation central venous pressure, risk of post operative AKI was significantly higher in group C than in group A (OR:1.897, 95%CI: 1.270-2.833, P = 0.002).Pre-operative elevated uric acid is an independent risk factor of AKI after cardiac surgery in elderly patients.",
        "keywords": [],
        "authors": [
            {
                "name": "Jiaqi Xu",
                "org": "Graduate School, Southern Medical University, Guangzhou 510515, China."
            },
            {
                "name": "Yuanhan Chen",
                "org": ""
            },
            {
                "name": "Xinling Liang",
                "org": "Email: xinlingliang@139.com."
            },
            {
                "name": "Penghua Hu",
                "org": ""
            },
            {
                "name": "Lu Cai",
                "org": ""
            },
            {
                "name": "Shengli An",
                "org": ""
            },
            {
                "name": "Zhilian Li",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            }
        ],
        "venue": "Zhonghua xin xue guan bing za zhi",
        "year": 2014
    },
    "T9Yt9e4Q": {
        "id": "T9Yt9e4Q",
        "title": "External corporate governance and financial fraud: cognitive evaluation theory insights on agency theory prescriptions",
        "abstract": "Research summary: Agency theory suggests that external governance mechanisms (e.g., activist owners, the market for corporate control, securities analysts) can deter managers from acting opportunistically. Using cognitive evaluation theory, we argue that powerful expectations imposed by external governance can impinge on top managersu0027 feelings of autonomy and crowd out their intrinsic motivation, potentially leading to financial fraud. Our findings indicate that external pressure from activist owners, the market for corporate control, and securities analysts increases managersu0027 likelihood of financial fraud. Our study considers external governance from a top manageru0027s perspective and questions one of agency theoryu0027s foundational tenets: that external pressure imposed on managers reduces the potential for moral hazard.Managerial summary: Many of us are familiar with stories about top managers “cooking the books” in one way or another. As a result, companies and regulatory bodies often implement strict controls to try to prevent financial fraud. However, cognitive evaluation theory describes how those external controls could actually have the opposite of their intended effect because they rob managers of their intrinsic motivation for behaving appropriately. We find this to be the case. When top managers face more stringent external control mechanisms, in the form of activist shareholders, the threat of a takeover, or zealous securities analysts, they are actually more likely to engage in financial misbehavior. Copyright © 2016 John Wiley u0026 Sons, Ltd.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Kelley School of Business Indiana University Indianapolis Indiana U.S.A"
            },
            {
                "name": "Brian L. Connelly",
                "org": "Raymond J. Harbert College of Business Auburn University Auburn Alabama U.S.A"
            },
            {
                "name": "Robert E. Hoskisson",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas U.S.A"
            }
        ],
        "venue": "Strategic Management Journal",
        "year": 2017
    },
    "FdSKJ3wJ": {
        "id": "FdSKJ3wJ",
        "title": "1,8-Naphthalimide-based dual-response fluorescent probe for highly discriminating detection of cys and H2S",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Kai-Bin Li",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            },
            {
                "name": "Wang-Bo Qu",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            },
            {
                "name": "Qiongxia Shen",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            },
            {
                "name": "Siqi Zhang",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            },
            {
                "name": "Lei Dong",
                "org": "Intitut de Chimie et Biochimie Moléculaires et Supramoléculaires, Laboratoire de Chimie Organique 2-Glycochimie, UMR 5246, CNRS and Université Claude Bernard Lyon 1, Université de Lyon, 1 Rue Victor Grignard, F-69622, Villeurbanne, France"
            },
            {
                "name": "De-Man Han",
                "org": "Department of Chemistry, Taizhou University, Jiaojiang, 318000, PR China"
            }
        ],
        "venue": "Dyes and Pigments",
        "year": 2020
    },
    "CzI0GrQ5": {
        "id": "CzI0GrQ5",
        "title": "Expression and Clinical Significance of Plasminogen Activator Inhibitor Type-1 in Human Glioma",
        "abstract": "Objective To investigate the expression and significance of plasminogen activator inhibitor type-1 in human glioma,and analyze its relationship with malignant biological behavior of human glioma,anddiscuss the role and significance of PAI-1 in human glioma.Methods PAI-1 protein expression was detected by immunohistochemical(ABC) method and ECL-Western blot in surgical samples of 41 patients with human glioma and 10 samples of normal brain tissue obtained from craniocerebral injury surgery.Results Along with the rise of glioma grade,the PAI-1 protein expression was also upregulated,but the level of PAI-1 in normal brain tissue was extremely much lower.There was significant difference among normal brain tissues,low-gradegliomas and high-grade gliomas(P <0.05).The expression of PAI-1 protein was correlated positively with pathological grade of glioma(P<0.05).Conclusion The high level of PAI-1 protein reflects a malignant biological behavior of human glioma,which indicate PAI-1 plays an important role in the tumorigenesis of glioma.",
        "keywords": [
            "Western blot",
            "Plasminogen activator inhibitor type-1",
            "Glioma",
            "Immunohistochemical"
        ],
        "authors": [
            {
                "name": "SU Xing",
                "org": "Dept.of Neurosurgery,The Affiliated Hospital of Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Dept.of Neurosurgery,The Affiliated Hospital of Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "HUANG Jian-fei",
                "org": "Dept.of Neurosurgery,The Affiliated Hospital of Nantong University,Nantong Jiangsu ,China"
            },
            {
                "name": "CHEN Jian",
                "org": "Dept.of Neurosurgery,The Affiliated Hospital of Nantong University,Nantong Jiangsu ,China"
            }
        ],
        "venue": "Journal of Kunming Medical University",
        "year": 2011
    },
    "n1s7JiOj": {
        "id": "n1s7JiOj",
        "title": "Non-ideal PCM to prevent temperature cracks in concrete",
        "abstract": "Phase change materials(PCM) can be applied in concrete to prevent thermal cracks smartly.Phase change material was added to fresh concrete when casting,latent heat in phase change material was released or absorbed in a certain temperature to control temperature field in concrete so as to control temperature cracks.It also discussed the principles of the selection of PCM type and temperature range of phase change.",
        "keywords": [
            "temperature control",
            "temperature cracks",
            "non-ideal",
            "phase change materials"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "HOU Jing-peng",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            }
        ],
        "venue": "Concrete",
        "year": 2008
    },
    "4jX8IZTb": {
        "id": "4jX8IZTb",
        "title": "Acute aristolochic acid nephropathy due to kaempfer dutchmanspipe root poisoning",
        "abstract": "A 73-year-old woman took about 20 g of kaemfer dutchmanpipe root powder for treating stomach discomfort.Ten minutes later,she developed vomiting.She did not resolve Despite symptomatic therapy.Three days later,she developed oliguria.A routine urine test revealed the following values:pH 9.0,Glu(+),PRO(┼┼),and KET(+).She had a BUN level of 17.8 mmol/L,a SCr level of 708 μmol/L,and a UA level of 294.5 μmol/L.A B-ultrasonography showed diffused parenchymatous lesions in the kidneys.She was diagnosed with acute aristolochic acid nephropathy and acute renal failure due to kaempfer dutchmanspipe root poisoning.After treatment with Jinshuibao capsules,dopamine,furosemide,sodium bicarbonate,hydrocortisone,and hemodialysis,the patient's urine volume gradually increased.Her renal function improved and the symptoms disappeared.At follow-up 3 months later,her renal function remained stable.",
        "keywords": [
            "kaempfer dutchmanspipe root",
            "acute aristolochic acid nephropathy"
        ],
        "authors": [
            {
                "name": "Huang Renfa",
                "org": "Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi Province,China"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi Province,China"
            },
            {
                "name": "Wu Jinyu",
                "org": "Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi Province,China"
            },
            {
                "name": "Tang Yu",
                "org": "Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi Province,China"
            },
            {
                "name": "Xie Liping",
                "org": "Department of Nephrology,the First Affiliated Hospital of Guangxi College of Traditional Chinese Medicine,Nanning ,Guangxi Province,China"
            }
        ],
        "venue": "Adverse Drug Reactions Journal",
        "year": 2007
    },
    "H9IAxEtr": {
        "id": "H9IAxEtr",
        "title": "Conversion pseudocapacitance-contributing and robust hetero-nanostructural perovskite KCo0.54Mn0.46F3 nanocrystals anchored on graphene nanosheet anodes for advanced lithium-ion capacitors, batteries and their hybrids",
        "abstract": "",
        "keywords": "",
        "authors": [
            {
                "name": "Danfeng Ying",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Yongfa Huang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Caini Tan",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Xiujuan Sun",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Ping Gao",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University,Xiangtan,P. R. China"
            }
        ],
        "venue": "Journal of Materials Chemistry",
        "year": 2019
    },
    "FLDlp6Qr": {
        "id": "FLDlp6Qr",
        "title": "Fluoxetine suppresses the immune responses of blood clams by reducing haemocyte viability, disturbing signal transduction and imposing physiological stress.",
        "abstract": "The antidepressant fluoxetine (FLX), a selective serotonin reuptake inhibitor, is widely prescribed for the treatment of depression and anxiety disorders. Nowadays, measurable quantities of FLX have been frequently detected in the aquatic ecosystems worldwide, which may pose a potential threat to aquatic organisms. Although the impacts of FLX exposure on immune responses are increasingly well documented in mammals, they remain poorly understood in aquatic invertebrates. Therefore, to gain a better understanding of the ecotoxicological effects of FLX, the impacts of waterborne FLX exposure on the immune responses of blood clam, Tegillarca granosa, were investigated in this study. Results obtained showed that both cellular and humoural immune responses in T. granosa were suppressed by exposure to waterborne FLX, as indicated by total counts of haemocytes (THC), phagocytic rate, and activities of superoxide dismutases (SOD) and catalase (CAT), suggesting that waterborne FLX renders blood clams more vulnerable to pathogen challenges. To ascertain the mechanisms explaining how waterborne FLX affects immune responses, haemocyte viabilities, intracellular Ca levels, in vivo concentrations of neurotransmitters, physiological stress conditions (as indicated by in vivo concentrations of cortisol), and expressions of key regulatory genes from Ca and neurotransmitter signal transduction, as well as immune-related signalling pathways, were examined after 10 days of FLX exposure by blood clams via 1, 10 and 100 μg/L waterborne FLX. The results obtained indicated that immune response suppression caused by waterborne FLX could be due to (i) inhibited haemocyte viabilities, which subsequently reduce the THC; (ii) altered intracellular Ca and neurotransmitter concentrations, which lead to constrained phagocytosis; and (iii) aggravated physiological stress, which thereafter hampers immune-related NFκB signalling pathways.",
        "keywords": [
            "Ca(2+) concentration",
            "Fluoxetine",
            "Immune responses",
            "Neurotransmitters",
            "Stress"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Xiaofan Guan",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Jiahuan Rong",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yu Tang",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Xueying Du",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "The Science of the total environment",
        "year": 2019
    },
    "t0SBVDda": {
        "id": "t0SBVDda",
        "title": "Ischemic colitis following colonoscopy:report of 4 cases",
        "abstract": "With the widespread utility of endoscopic technology,all kinds of complications increase.Ischemic colitis following endoscopic examinations are very rare.Here,4 cases of ischemic colitis following colonoscopy from Feb.2009 to Oct.2009 were reported.This paper tries to explore the pathogenesis through analyzing these clinical data with reported literatures and raise awareness of this complication.",
        "keywords": [
            "Colonoscopy",
            "Complications",
            "Ischemic colitis"
        ],
        "authors": [
            {
                "name": "SHAN Jing",
                "org": "Department of Gastroenterology,the 3rd People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,the 3rd People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "SUN Xiaobin",
                "org": "Department of Gastroenterology,the 3rd People's Hospital of Chengdu,Chengdu ,China"
            },
            {
                "name": "XI Weidong",
                "org": "Department of Gastroenterology,the 3rd People's Hospital of Chengdu,Chengdu ,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2010
    },
    "8tNEpIsJ": {
        "id": "8tNEpIsJ",
        "title": "Ocean acidification adversely influences metabolism, extracellular pH and calcification of an economically important marine bivalve, Tegillarca granosa.",
        "abstract": "Oceanic uptake of CO from the atmosphere has significantly reduced surface seawater pH and altered the carbonate chemistry within, leading to global Ocean Acidification (OA). The blood clam, Tegillarca granosa, is an economically and ecologically significant marine bivalve that is widely distributed along the coastal and estuarine areas of Asia. To investigate the physiological responses to OA, blood clams were exposed to ambient and three reduced seawater pH levels (8.1, 7.8, 7.6 and 7.4) for 40 days, respectively. Results obtained suggest that OA suppresses the feeding activity and aerobic metabolism, but elevates proteins catabolism of blood clams. OA also causes extracellular acidosis and decreases haemolymph Ca concentration. In addition, our data also suggest that OA impairs the calcification process and inner shell surface integrity. Overall, OA adversely influences metabolism, acid-base status and calcification of blood clams, subsequently leading to a decrease in the fitness of this marine bivalve species.",
        "keywords": [
            "Acid-base status",
            "Bivalve",
            "Calcification",
            "Metabolism",
            "Ocean acidification",
            "Tegillarca granosa"
        ],
        "authors": [
            {
                "name": "Xinguo Zhao",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Saixi Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Cheng Guo",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China."
            },
            {
                "name": "Wandong Fu",
                "org": "Zhejiang Marine Development Research Institute, Zhoushan 316021, PR China."
            },
            {
                "name": "Xueliang Chai",
                "org": "Zhejiang Mariculture Research Institute, Wenzhou 325000, PR China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou 310058, PR China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "Marine environmental research",
        "year": 2017
    },
    "adhTwHEg": {
        "id": "adhTwHEg",
        "title": "Integrierte Mikrokanäle für 3D Through-Silicon-Architekturen",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "daoqiang lu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "yiqun bai",
                "org": ""
            },
            {
                "name": "qing zhoz",
                "org": ""
            },
            {
                "name": "jiangqi he",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2006
    },
    "gYxIeSOY": {
        "id": "gYxIeSOY",
        "title": "Study on a new IR nonlinear optics crystal CsGeCl3",
        "abstract": "Oxides and chalcopyrites semiconductor materials have infrared laser properties noticed in the infrared region, but their application was restricted due to their disadvantages. So CsGeCl 3 has been studied because of its very wide-band transparency range and higher nonlinear optical coefficients. This letter will report on the crystal growth and properties of CsGeCl 3 . Transparent crystals have been grown from a HCl–EtOH–CsCl mixture solution and its transparency region was found to be up to 20 μm. It has no congruent melting point and it decomposes at 325°C. Powder double-frequency studies show that its SHG signal was about 5 times to that of KDP and damage threshold was up to 200 M W/cm 2 . These results show that CsGeCl 3 is a potential material for frequency-doubling application in the infrared region. PACS 42.70.Mp 81.10.Dn Keywords Infrared Frequency doubling CsGeCl 3 Recently, because of the demands of military and other civil applications, many countries dedicated high efforts in infrared laser studies. The research of IR NLO materials becomes a new research focus. Oxide crystals have reasonable nonlinear coefficients and high laser-damage thresholds. However, many of these oxide materials have high absorption in the mid-wave infrared (3–5 μm) and long-wave infrared (8–12 μm), so their applications in the IR were restricted. Narrower band gap semiconductor materials such as chalcopyrites have transparencies that extend further into the long-wave infrared and also have large NLO coefficients. However, the difference of their components' vapor pressure makes it difficult to grow stoichiometric single crystals. Other problems such as inadequate short-wavelength transmission cut off, extrinsic absorption and poor thermal properties also restrict their applications. Recently, CsGeCl 3 (CGC) has been investigated and it is a potential NLO material in the infrared region [1] . CsGeCl 3 has a distorted perovskite structure like that of. The ratio of lattice parameters of CsGeCl 3 and BaTiO 3 is 1.35. GeCl 3 − has a similar structure to that of TiO 3 2− , GeCl 3 − anion group exists as GeCl 6 octahedron structure in the crystal lattice and has a distortion along the 3 axes [2,3] . Its space group is R3(No.146). This structure molecule has high molecule super polarizablity β and high NLO coefficient. The chloride atom is much heavier than oxygen, the optical absorption from the stretching phonon mode occurs at a much longer wavelength. CGC exhibits a very wide-band transparency range, extending from 380 nm to over 20 μm as illustrated by the transmission spectrum given in Fig. 1 . This paper will report some research work on growth of CsGeCl 3 . Christensen and Tananaev et al. use different methods to synthesize CGC [2,4] . Both are complex and have low production ratio. We did some research about the material properties and used a modify method to synthesize CGC. We loaded 30% H 3 PO 2 100 g and 100 ml HCl, 10 g GeO 2 and 17 g CsCl into a 1000 ml beaker, and then heated to 85–90°C. The solution was vigorously mixed for 5 h and then cooled to room temperature. A white precipitate was produced. The reaction equation is as follows: H 3 PO 2 +4HCl+2GeO 2 +2CsCl=H 3 PO 4 +2CsGeCl 3 ↓ +2H 2 O. We recrystallized it from 1 : 1 conc. HCl and alcohol solution, and received colorless crystals. The yield was 26.8 g and the production ratio was 90%. The production was decomposed by KNO 3 in melting NaOH. Cl content was determined by AgNO 3 and the value was 33.81wt%, near to the theoretical value of 34.10%. From X-ray powder diffraction, we confirmed that our crystals are CsGeCl 3 [2] . Fig. 1 shows the transparency spectrum of CGC. We could see that CGC had a transparency from 0.4 to 20 μm and no absorption peak. Using DTA1700 high-temperature analysis instrument, we measured the thermal properties. Christensen et al. observed in CGC a discontinued DTA curve at 155 and 325°C, so he considered that CGC had a phase transition at 155°C and a melting point of 325°C . But we have not observed the curve at 155°C and from our DTA-TG diagram, we can conclude that CGC decomposes at 325°C ( Fig. 2 ). CGC's powder NLO coefficient was compared with KDP using a semi-quantitative method as shown in Fig. 3 . Nd : YAG 1.064 μm laser was divided into two parts to irradiate the CGC pressed powder pellet and a KDP sample. The value obtained for CGC is about 5 times that of KDP powder at 1.06 μm and damage threshold is greater than 200 M W/cm 2 . CGC single-crystal was grown from solution by lowering the temperature. We have made studies on the crystal morphology in different kinds of solvents. We selected HCl–EtOH–CsCl, HCOOH–CsCl and HCOOH–EtOH as solvent study for micro-crystallization and selected HCl–CsCl–EtOH and HCOOH–EtOH–CsCl solution. Recently, CsGeCl 3 single-crystal of about 5×5×5 mm 3 ( Fig. 4a ) was grown from HCl–CsCl–EtOH solution. The CsGeCl 3 crystals were transparent and colorless, having triangular facets. The natural faces identified with X-ray detector, of the top and bottom faces were {0 0 1} and the other faces were {1 0 1} ( Fig. 4b ). Acknowledgements This work was supported by the National Natural Science Foundation (69878016) and State Key Lab. of Crystal Material's Foundation. References [1] M.D. Ewbank, F. Cunningham, R. Borwick, M.J. Rosker, P. Gunter, CLEO’97 CFA7 (1997) 462. [2] A.N Christensen S.E Rasmussen Acta. Chem. Scand. 19 2 1965 421 [3] B.R Serr G Heckert H.W Rotter G Thiele J. Mol. Struct. 348 1 1995 95 [4] I.V. Tananaev, B.F. Dzhurinskii, Yu.N. Mikhailov, Zh. Neorgan. Khim, 9 (7) (1964) 1570.",
        "keywords": [
            "null"
        ],
        "authors": [
            {
                "name": "Qingtian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Shandong, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Shandong, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Shandong, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Wei Shi",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Shandong, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2000
    },
    "2PBefWNi": {
        "id": "2PBefWNi",
        "title": "New electro-optics polymer DCNP/PEK-c film",
        "abstract": "New polymer host-guest system DCNP/PEK-c films have been investigated. The films were prepared by spin coating method. New films have higher Tg and larger electro-optic coefficient as well as low optic transmission loss.",
        "keywords": [
            "optical filters",
            "optical waveguides",
            "nonlinear optics",
            "temperature"
        ],
        "authors": [
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Pacific Rim Conference on Lasers and Electro-Optics, CLEO - Technical Digest",
        "year": 2001
    },
    "8ggd1nCU": {
        "id": "8ggd1nCU",
        "title": "Erratum to: The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China ; Southern Medical University, Guangzhou, China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China"
            },
            {
                "name": "Juan Ma",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China ; Southern Medical University, Guangzhou, China"
            },
            {
                "name": "Alexis Sloan",
                "org": "Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL, 33136, USA"
            },
            {
                "name": "Christian Faul",
                "org": "Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL, 33136, USA"
            },
            {
                "name": "Changli Wei",
                "org": "Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, FL, 33136, USA"
            },
            {
                "name": "Jochen Reiser",
                "org": "Department of Medicine, Rush University Medical Center, Chicago, IL, 60612, USA"
            },
            {
                "name": "Yun Yang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China ; Southern Medical University, Guangzhou, China"
            },
            {
                "name": "Shuangxin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China"
            },
            {
                "name": "Wenjian Wang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan No. 2 Road, Guangzhou, 510080, China"
            }
        ],
        "venue": "Journal of Molecular Medicine",
        "year": 2012
    },
    "RXyuvYAS": {
        "id": "RXyuvYAS",
        "title": "Cenozoic Tectonic Evolution of the Arcuate Structures in the Northeast Tibetan Plateau",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "shi wei",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "h u jianmin",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "chen hong",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "liu yuan",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            },
            {
                "name": "chen peng",
                "org": "Chinese Acad Geol Sci, Inst Geomech, Beijing 100081, Peoples R China"
            }
        ],
        "venue": "Acta Geologica Sinica-english Edition",
        "year": 2015
    },
    "aFaV7ekh": {
        "id": "aFaV7ekh",
        "title": "Study on application properties of PCM mortars with paraffin",
        "abstract": "Temperature cracks in concrete can be controlled using PCM(phase change material) smartly in concrete.The application properties of PCM mortars with paraffin were studied in this paper.Workability,compressive strength,flexible strength and deformation property of PCM under different ages were tested on concrete with paraffin particle and paraffin emulsion.Mercury intrusion porosimeter was used to analyze pore structure of mortar.Results show that mortar with emulsion paraffin has better deformation property than that of mortar with paraffin particle;however,mortar with paraffin particle has better workability and strength with lower porosity and better pore structure than that of mortar with emulsion paraffin.",
        "keywords": [
            "phase change material",
            "paraffin",
            "energy-storing mortar"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,Jilin,China"
            },
            {
                "name": "HOU Jingpeng",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,Jilin,China"
            }
        ],
        "venue": "New Building Materials",
        "year": 2012
    },
    "4f7P4zAM": {
        "id": "4f7P4zAM",
        "title": "Conservation genetics and geographic patterns of genetic variation of endangered shrub Ammopiptanthus (Fabaceae) in northwestern China",
        "abstract": "Phylogeographic patterns of Ammopiptanthus in northwestern China were examined with internal transcribed spacer (ITS) and three chloroplast intergenic spacers (trnH–psbA, trnL–trnF, and trnS–trnG). Two ITS genotypes (a–b) and 8 chloroplast haplotypes (A–H) were detected. Both ITS genotypes and chloroplast lineages were split in two geographic regions: western Xinjiang and the Alxa Desert. This lineage split was also supported by AMOVA analysis and the Mantel test. AMOVA showed that 89.81 % of variance in Ammopiptanthus occurred between the two geographic regions, and correlation between genetic distances and geographical distances was significant (r = 0.757, p u003c 0.0001). All populations in western Xinjiang shared haplotype A with high frequency, and range expansion was strongly supported by negative Fu’s FS value, and mismatch distribution analysis, whereas populations in the Alxa Desert had higher genetic diversity and structure. We speculate that the cold and dry climate during the early Quaternary fragmented habitats of the species, limiting gene flow between regions, and interglacial periods most likely led to the range expansion in western Xinjiang. The low genetic diversity of Ammopiptanthus indicate a significant extinction risk, and protective measures should be taken immediately.",
        "keywords": [
            "Ammopiptanthus",
            " Allopatric divergence",
            " Range expansion",
            " The Alxa Desert",
            " Western Xinjiang"
        ],
        "authors": [
            {
                "name": "Zhihao Su",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Borong Pan",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Ming-Li Zhang",
                "org": "Chinese Academy of Sciences"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Ürümqi,China"
            }
        ],
        "venue": "Conservation Genetics",
        "year": 2016
    },
    "V7qmlcXA": {
        "id": "V7qmlcXA",
        "title": "Clinical analysis of therapeutic endoscopic intervention on acute nonvariceal upper gastrointestinal bleeding (ANVUGIB)",
        "abstract": "Objective To study the acute non-variceal upper gastrointestinal bleeding in endoscopic treatment related variables on the length of hospital stay and blood volume in order to make better use of hospital resources.Methods Chengdu Third People's Hospital of 91 patients with acute non-variceal upper gastrointestinal bleeding were retrospectively analyzed,in accordance with the relevant variables(endoscopic treatment,treatment time,patient age,blood pressure,heart rate,disease character Patients with the disease)in statistics,research the various factors change and hospitalization time and the relationship between transfusion.Results The single method to stop bleeding group and the titanium clip group were associated with injection therapy and blood transfusion in the hospital on time and the difference was statistically significant(P <0.05);beyond 48 h intervention therapy group and the 24 h transfusion within the intervention group quantitative difference is also significant(P <0.05);<60years old and between 60 to 80 age group difference in hospitalization time was significant(P<0.05);60～80 years old and>80 age group Comparison between the blood transfusion was no significant difference on(P>0.05);admission systolic blood pressure>100 mm Hg and heart rate<100 times/min in the patients length of stay of less than systolic blood pressure and blood transfusion>100 mm Hg and heart rate> 100 times/min in patients,and the difference was statistically significant(P<0.05);lesions hospital stay and blood transfusion in the significant difference(P<0.05);is determined to merge cerebral vascular disease in the hospital stay and blood transfusion was no significant difference(P >0.05).Conclusion The emergency endoscopic hemostasis joint program can reduce the hospital stay,and admission heart rate and blood pressure,fluid and timely given the strict observation of stable vital signs and endoscopic treatment can reduce the amount of blood transfusion and shorter hospital stay,reduce medical care costs.",
        "keywords": [
            "Endoscopic intervention",
            "Acute non-variceal upper gastrointestinal bleeding"
        ],
        "authors": [
            {
                "name": "LI Yu",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "SUN Xiao-bin",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,Third People's Hospital of Chengdu,Chengdu "
            }
        ],
        "venue": "Jilin Medical Journal",
        "year": 2010
    },
    "d0DWhZiY": {
        "id": "d0DWhZiY",
        "title": "Investigation of GaAs photoconductive switches triggered by 900nm semiconductor lasers",
        "abstract": "Experiment of a lateral semi-insulating GaAs photoconductive semiconductor switch (SI-GaAs PCSS) with different electrode gaps triggered by 900nm semiconductor laser is reported. With the biased voltage of 0.2KṼ3.0KV, the linear electrical pulse is outputted by SI-GaAs PCSS. When laser energy is very low, the semi-insulating GaAs PCSS with 1.5mm electrode gap is triggered by laser pulse,the output electrical pulse samples is instable. When the energy of the laser increases, the amplitude and the width of the electrical pulse also increase. It indicates that a stable electrical pulse is obtained while laser energy is high. With the biased voltage of 2.8kV, the SI-GaAs PCSS with 3mm electrode gap is triggered by laser pulse about 10nJ in 200ns at 900nm. The SI-GaAs PCSS switches a electrical pulse with a voltage up to 80V. The absorption mechanism by Franz-Keldysh effect under high-intensity electric field and EL2 deep level defects is discussed. © 2009 SPIE.",
        "keywords": [
            "franz-keldysh effect",
            "linear mode",
            "photoconductive switches",
            "semi-insulating gaas",
            "semiconductor laser pulse",
            "ultra-fast electrical pulse",
            "semiconductors",
            "semiconductor lasers",
            "switches",
            "electric field",
            "gallium arsenide",
            "electrodes",
            "absorption",
            "lasers"
        ],
        "authors": [
            {
                "name": "Ma Deming",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Shi Wei",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Ma Xiangrong",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Wang Xinmei",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Pei Tao",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            }
        ],
        "venue": "Proceedings of SPIE - The International Society for Optical Engineering",
        "year": 2009
    },
    "OtONS40M": {
        "id": "OtONS40M",
        "title": "Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis.",
        "abstract": "Accumulation of tissue advanced glycation end products (AGEs) is a marker of cumulative glycemic and/or oxidative stress. Cutaneous AGEs levels measured by skin autofluorescence correlate well with cardiovascular outcomes in diabetes and hemodialysis (HD) patients. The present study aimed to compare tissue AGEs levels with peritoneal dialysis (PD) and HD patients and to evaluate the relationship between skin autofluorescence and cardiovascular morbidity in patients on PD.A total of 2388 maintenance dialysis patients (613 PD and 1775 HD) were enrolled in this cross-sectional study. Skin autofluorescence was measured non-invasively with an autofluorescence reader. Cardiovascular morbidity was defined as clinically diagnosed ischemic heart disease, heart failure, stroke or peripheral vascular disease from initiation of dialysis.More than 90% of patients on both PD and HD had met current dialysis adequacy targets. Compared to HD group, PD patients receiving conventional glucose-containing dialyzate had significantly higher skin autofluorescence values in each category of age and dialysis duration, irrespective of the presence or absence of diabetes. In PD patients, skin autofluorescence values were strongly correlated with the duration of PD and glucose exposure dose and independently associated with cardiovascular morbidity. Multivariate analysis revealed that glucose exposure dose and skin autofluorescence were the strongest risk factors for cardiovascular morbidity in PD patients after adjustment by age, gender, and other classic- or uremic-related risk factors.Accumulation of tissue AGEs provides a potential link between PD exposure of metabolic stress and progression of cardiovascular disease in patients on PD.",
        "keywords": [
            "advanced glycation end products",
            "peritoneal dialysis",
            "skin autofluorescence",
            "cardiovascular morbidity",
            "glucose"
        ],
        "authors": [
            {
                "name": "Jianping Jiang",
                "org": "Division of Nephrology, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, China."
            },
            {
                "name": "Pingyan Chen",
                "org": ""
            },
            {
                "name": "Jianghua Chen",
                "org": ""
            },
            {
                "name": "Xueqing Yu",
                "org": ""
            },
            {
                "name": "Di Xie",
                "org": ""
            },
            {
                "name": "Changlin Mei",
                "org": ""
            },
            {
                "name": "Fei Xiong",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Wei Zhou",
                "org": ""
            },
            {
                "name": "Xusheng Liu",
                "org": ""
            },
            {
                "name": "Shiren Sun",
                "org": ""
            },
            {
                "name": "Ping Zhang",
                "org": ""
            },
            {
                "name": "Xiao Yang",
                "org": ""
            },
            {
                "name": "Yixiang Zhang",
                "org": ""
            },
            {
                "name": "Yanmin Zhang",
                "org": ""
            },
            {
                "name": "Xinling Liang",
                "org": ""
            },
            {
                "name": "Zhimin Zhang",
                "org": ""
            },
            {
                "name": "Qizhan Lin",
                "org": ""
            },
            {
                "name": "Yan Yu",
                "org": ""
            },
            {
                "name": "Toshio Miyata",
                "org": ""
            },
            {
                "name": "Jianwei Tian",
                "org": ""
            },
            {
                "name": "Min Liang",
                "org": ""
            },
            {
                "name": "Weihong Luo",
                "org": ""
            },
            {
                "name": "Xin Xu",
                "org": ""
            },
            {
                "name": "Fanfan Hou",
                "org": ""
            }
        ],
        "venue": "Atherosclerosis",
        "year": 2012
    },
    "Zcl1w1Zp": {
        "id": "Zcl1w1Zp",
        "title": "Analysis of high voltage dielectric insulation materials of XLPE by THz-TDS system",
        "abstract": "",
        "keywords": [
            "spectroscopy",
            "fourier transforms",
            "refractive index",
            "terahertz radiation"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "zhijin yan",
                "org": ""
            },
            {
                "name": "lei yang",
                "org": ""
            },
            {
                "name": "yang dai",
                "org": ""
            },
            {
                "name": "like zhang",
                "org": ""
            },
            {
                "name": "kangkang bian",
                "org": ""
            },
            {
                "name": "lei hou",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "1MsIBhTY": {
        "id": "1MsIBhTY",
        "title": "PHYLOGENETIC RELATIONSHIP AND LENGTH VARIATION IN THE FIRST RIBOSOMAL INTERNAL TRANSCRIBED SPACER OF CYNOGLOSSINAE SPECIES",
        "abstract": "Previous studies on phylogenetic relationship of Cynoglossinae fish species relied mostly on morphological data. However,the morphology-based phylogeny and classification of them remain controversial.Recently,combined with morpho- logical data,large advancement has been made on molecular level and has yielded interesting results in regard to tonguefish taxa. In this study,the first ribosomal internal transcribed spacers (ITS 1) of nuclear ribosomal DNA from six species of the subfamily Cynoglossinae were used for phylogenetic analysis.The significant length variation of ITS I region was observed,with range of 404—744bp in length.Clade were established of three well-morphologically-defined groups.The first group,including C.pur- pureomaculatus and C.abbreviatus,was 404—405bp long;C.sinicus and P.japonica was,as the second group,in length of 462—463bp;and C.oligolepis and C.lighti,the last group,was 741—744bp long.The alignment length of ITS1 was 756 long, with variable sites of 286,of which 285 were parsimony informative.High variability was detected in the ITS1 region,and the conserved motifs were very short except for the motif (ACCCAACTCTCC),which was common for all species.The sequences contained relatively high GC content (from 66.2% to 69.5%),averaging 67.2%.The mean intra-group distance was 0.00248, 0.00217 and 0.00169 respectively,and the mean in-ter-group distance between GroupsⅠandⅡwas 0.3845,betweenⅡandⅢwas 0.9088,and betweenⅠandⅢwas 0.8685.The intra-group distances were very smaller than those of inter-group, suggesting that the species in the same group have very close relationship in evolution.The DNA data of these fishes were proc- essed using neighbor-joining (NJ) and maximum parsimony (MP) methods to build phylogenetic relationships within the sub- family of them.Based on morphological,nuclear DNA and mitochondrial DNA data available so far,it is regarded that C.abbre- viatus and C.purpureomaculatus could be the same species with different morphs.Different from morphological taxonomy,C. sinicus of genus Cynoglossus and P.japonica (the only one species under genus Paraplagusia) were placed in a same clade with support of a high bootstrap value,and C.oligolepis and C.lighti were grouped in a clade together.More in-depth researches on more samples are suggested to further clarify the position of the fish taxonomy.",
        "keywords": [
            "Phylogenetic relationship",
            "ITS1",
            "Cynoglossinae",
            "Length variation"
        ],
        "authors": [
            {
                "name": "XU Hui",
                "org": "The Key Laboratory of Mariculture,Ministry of Education,Fisheries College,Ocean University of China.Qingdao,"
            },
            {
                "name": "LI Jun",
                "org": "Institute of Oceanology,Chinese Academy of Sciences,Qingdao,"
            },
            {
                "name": "KONG Xiao-Yu",
                "org": "South China Sea Institute of Oceanology,Chinese Academy of Sciences Guangzhou,"
            },
            {
                "name": "XIAO Zhi-Zhong",
                "org": "Institute of Oceanology,Chinese Academy of Sciences,Qingdao,"
            },
            {
                "name": "LI Yu-Long",
                "org": "The Key Laboratory of Mariculture,Ministry of Education,Fisheries College,Ocean University of China.Qingdao,"
            },
            {
                "name": "ZHANG Yan-Chun",
                "org": "The Key Laboratory of Mariculture,Ministry of Education,Fisheries College,Ocean University of China.Qingdao,"
            },
            {
                "name": "SHI Wei",
                "org": "The Key Laboratory of Mariculture,Ministry of Education,Fisheries College,Ocean University of China.Qingdao,"
            },
            {
                "name": "WEI Zheng-Peng",
                "org": "The Key Laboratory of Mariculture,Ministry of Education,Fisheries College,Ocean University of China.Qingdao,"
            },
            {
                "name": "YU Zi-Niu",
                "org": "South China Sea Institute of Oceanology,Chinese Academy of Sciences Guangzhou,"
            }
        ],
        "venue": "Oceanologia Et Limnologia Sinica",
        "year": 2008
    },
    "LTjpGHDT": {
        "id": "LTjpGHDT",
        "title": "Improvement of the interferometric method for measuring electro-optic coefficients of poled polymer thin films.",
        "abstract": "The interferometric method for measuring the linear electro-optic coefficients of polymer films has been improved. This improved method is based on using the antipiezoelectric effect of a quartz crystal to compensate for the change in the optical path length that is due to the electro-optic effect of a polymer film. The electro-optic coefficients of six kinds of new poled polymer film have been determined at a wavelength of 633 nm by this new method. This technique offers a simple, rapid, and highly sensitive method for measuring the electro-optic coefficients of polymer films.",
        "keywords": [
            "spectrum",
            "nonlinear optics",
            "optical path length",
            "polymers",
            "thin film"
        ],
        "authors": [
            {
                "name": "Xin Yin",
                "org": ""
            },
            {
                "name": "Qiwei Pan",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "Applied optics",
        "year": 2002
    },
    "sNYz5zAU": {
        "id": "sNYz5zAU",
        "title": "The New Progress in the Study of Mesozoic Tectonics of South China",
        "abstract": "Mesozoic tectonic regime underwent the transform from the Meso-Tethyan tectonic domain to the west Pacific tectonic domain,which caused intense intraplate orogenesis and magmatism in South China,forming a wide and complex intracontinental orogen and igneous province in this region of East Asia.Some progresses have been achieved recently in the study of this Mesozoic tectonics of South China,which are summarized as follows:(1) On the basis of field analysis of fault kinematics affecting different lithostratigraphic units of the Yuanma basin in central South China,a five-stage tectonic stress evolution history from Late Mesozoic to Early Cenozoic period was established,which included Middle-Late Jurassic E-W compression,Early Cretaceous NW-SE extension,Early Cretaceous NW-SE compression,Late Cretaceous N-S extension and Paleogene NE-SW compression.The change in tectonic stress directions was interpreted in terms of the change either in plate tectonic settings or in deep-seated crustal process.(2) Superposed folds involving Late Paleozoic to Mesozoic strata in Hunan Province were recognized;it is considered that these cross folds might record the effects of plate boundary tectonics,i.e.,the earlier W-E to WNW-ESE trending folds were formed in response to the Triassic collision of the South China Block with the North China Block and the Indochina Block,and the late NE to NNE trending folds were generated as the far-field effect of a low angle subduction of the Paleo-Pacific oceanic plate beneath the South China Block,which occurred in Mid-Late Jurassic.(3) The Hengshan metamorphic core complex was determined on the basis of detailed field investigation of a normal detachment fault zone developed along the western margin.SHRIPM U-Pb dating of zircons from strongly sheared albite made sure that the normal faulting was initiated in Early Cretaceous,at about 137 Ma.(4) Field observations and U-Pb dating of zircons revealed that the Changle-Nan’ao tectonic zone along the coast of southeast China corresponds to a Late Mesozoic orogenic zone formed in Late Jurassic to Early Cretaceous;it was materialized by gneissic granites,migmatites and amphibolite facies metamorphic rocks,which were dated to be 147-135 Ma.This orogenic zone began to collapse in 135-117 Ma,characterized by fine-grained granites.Based on the above results,this paper discusses the manifestations and plate tectonic backgrounds of the Indosinian and Yanshannian movements,and the time of the change from the compressive tectonic regime to the extensional region in Early Cretaceous.",
        "keywords": [
            "intra-continental orogenesis",
            "Yuanma basin",
            "tectonic stress field",
            "South China",
            "Mesozoic tectonics change in tectonic regime",
            "cross folds",
            "Changle-Nan’ao tectonic zone"
        ],
        "authors": [
            {
                "name": "ZHANG Yue-qiao",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "DONG Shu-wen",
                "org": " Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "LI Jian-hua",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "CUI Jian-jun",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "SU Jin-bao",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            },
            {
                "name": "LI Yong",
                "org": " 1) Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            }
        ],
        "venue": "Acta Geoscientica Sinica",
        "year": 2012
    },
    "CfyNX30j": {
        "id": "CfyNX30j",
        "title": "Cenozoic evolution of the Haiyuan fault zone in the northeast margin of the Tibetan Plateau",
        "abstract": "The Haiyuan fault zone,one of intensive deformational zones in the northeastern Tibetan Plateau,records the information about the northeastward growth of the Tibetan Plateau.On the basis of detailed structural measuring,we proposed the sequences of the Cenozoic paleo-stress fields and the tectonic evolution of the Haiyuan fault zone.Our studies show a five-stage tectonic evolution as follows.The first was the widespread development of the basins along the Haiyuan fault zone from the Eocene to the Miocene due to the NW SE extension;secondly,the Haiyuan fault zone was featured by right strike-slip activity in the late Miocene to the Pliocene controlled by the NNE SSW compression;thirdly,the fault intensively thrusted northeastward in the Late Pliocene to the Early Pleistocene owing to the NE SW compression,which resulted in the geomorphic formation;fourthly,Late Pleistocene basins occurred,caused by the NE SW extension;lastly,Haiyuan fault zone was marked by sinistral strike-slip movement since the later Late pleistocene,and some pull-part basins formed along the fault.The neotectonics of the Haiyuan fault zone will provide some new structural evidences for probing the northeastward extending of the Tibetan Plateau.",
        "keywords": [
            "Cenozoic",
            "Haiyuan fault zone",
            "Northeastern Tibetan Plateau",
            "Stress field",
            "Tectonic evolution"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "LIU Yuan",
                "org": "College of Earth Science and Resources,Chang'an University,Xi'an ,China"
            },
            {
                "name": "LIU Yang",
                "org": "Faculty of Land Resource Engineering,Kunming University of Science and Technology,Kunming ,China"
            },
            {
                "name": "CHEN Peng",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "CHEN Long",
                "org": "School of Geosciences and Environmental Engineering,Central South University,Changsha ,China"
            },
            {
                "name": "CEN Min",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "HUANG Xingfu",
                "org": "School of Earth Sciences and Resources,China University of Geosciences%%#Beijing%%#,Beijing ,China"
            },
            {
                "name": "LI Hengqiang",
                "org": "School of Earth Sciences and Resources,China University of Geosciences%%#Beijing%%#,Beijing ,China"
            }
        ],
        "venue": "Earth Science Frontiers",
        "year": 2013
    },
    "ZnsTCOQ8": {
        "id": "ZnsTCOQ8",
        "title": "Study on the Lightning Intruding Over-voltage in 750kV GIS Substation",
        "abstract": "There are many factors affecting the lightning intruding over-voltage in substation, except impulse corona and the tower model, the mode and length of GIS outgoing line are also the factors. On the basis of the Q-V characteristics of transmission lines, in this paper, a simple circuit model is presented to simulate characteristics of corona on the transmission lines and the effect of corona on lightning over voltage has been studied. Three tower models that is lumped inductance model, single surge impedance model and multi-surge impedance model are built, and the effect of tower model on lightning over voltage has been studied. Considering the influence of every factor,through two types of lightning stroke, that is lightning stroke on the top of a tower and shielding failure, the lightning over-voltages on circuit breaker(CB), current transformer(CT) and transformer are calculated by EMTP when lightning waves intrude into 750kV GIS substation in this paper. The study indicates that corona makes lightning intrusive wave attenuate and distort greatly, so the amplitude and gradient of lightning wave are reduced greatly, the attenuation in the section of ingoing line caused by corona takes up about 5% of the total lightning over voltage. Among three tower models, the over voltage derived from lumped inductance model is bigger than that of single surge impedance, and the over voltage derived from single surge impedance model is bigger than that of multi-surge impedance model. The discrepancy between three models is nearly 10%.",
        "keywords": [
            "impulse corona",
            "lightning intruding over-voltage",
            "tower model",
            "GIL",
            "GIS"
        ],
        "authors": [
            {
                "name": "CHEN Liangjin",
                "org": "Zhejiang Electric Power Test and Research Institute, Hangzhou , China"
            },
            {
                "name": "LI Sinan",
                "org": "Zhejiang Electric Power Test and Research Institute, Hangzhou , China"
            },
            {
                "name": "XIE Peng",
                "org": "School of Electrical Engineering, Xi’an Jiaotong University, Xi’an , China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering, Xi’an Jiaotong University, Xi’an , China"
            }
        ],
        "venue": "High Voltage Engineering",
        "year": 2006
    },
    "D8Z44m91": {
        "id": "D8Z44m91",
        "title": "Design on High-Speed Data Acquisition System based on Ethernet",
        "abstract": "The design of high-speed data acquisition system based on Ethernet is discussed in this paper.It is introduced that how to using LPC2292 ARM to control RTL8019AS to realize the hardware design of high-speed data transmission based on TCP/IP protocol.At last,the method of using VB to transfer Winsock to complete data reception is descriped.",
        "keywords": [
            "high-speed data acquisition",
            "VB",
            "RTL8019AS",
            "ARM",
            "Winsock",
            "LPC2292"
        ],
        "authors": [
            {
                "name": "Li Manchang",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Shi Wei",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Sun Jian",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Jiang Lihua",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Wu Yanli",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            }
        ],
        "venue": "Engineering & Test",
        "year": 2010
    },
    "z65MU8RF": {
        "id": "z65MU8RF",
        "title": "Tegaserod for the treatment of irritable bowel syndrome:a systematic review",
        "abstract": "Objective To assess the effectiveness and safety of tegaserod in the treatment of patients with irritable bowel syndrome(IBS).Methods A systematic review of randomized controlled trials(RCTs)of tegaserod for constipation predominant or non-diarrhoea predominant IBS was performed.Trials were identified by searching MEDLINE,EMBASE,the Cochrane Library,Chinese Biological Medicine Database,CNKI Chinese Journal Full-Text Database and the USA Food and Drug Administration(http://www.fda.gov).Results Thirteen trials involving 7 189 patients were included.For the patients with constipation predominant IBS,the responder rates for the Subjects Global Assessment(SGA)of relief at endpoint were significantly higher with tegaserod 12 mg(OR 1.33,95%CI=1.15-1.53)and 4 mg(OR 1.25,95%CI=1.03-1.53)compared with placebo,with a number needed to treat(NNT)of 14 and 20 respectively.For the patients with non-diarrhoea predominant IBS,the proportion of patients with overall satisfactory relief was greater in the tegaserod group than that in the placebo(OR 1.77,95%CI=1.39-2.26,NNT=8).Tegaserod did not significantly improve the symptom of abdominal pain/discomfort.The OR was 1.22(95%CI=0.86-1.73)and 1.14(95%CI=0.77-1.69)in tegaserod 12 mg and 4 mg compared with placebo,respectively.Effects of tegaserod on bloating were not consistent across the studies.Some GI symptoms such as number of bowel movements and stool consistency were improved with tegaserod.Diarrhoea was significantly higher in the tegaserod group compared with placebo(OR 3.40,95%CI=2.51-4.61),with a number needed to harm(NNH)of 17.Two patients with coronary artery disease were reported in the tegaserod group.There was no significant difference in serious adverse events between the tegaserod and placebo groups.The OR was 0.74(95%CI=0.35-1.58).Conclusions Tegaserod is an effective in relieving global IBS symptoms for patients with non-diarrhoea predominant IBS,but it might not improve symptoms of abdominal pain/discomfort and bloating.The major side-effect is diarrhoea.",
        "keywords": [
            "Meta-analysis",
            "Systematic review",
            "Irritable bowel syndrome",
            "Tegaserod"
        ],
        "authors": [
            {
                "name": "SUN Xiaobin",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "NONG Chunyan",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "CHAO Qichang",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "LI Yu",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "ZENG Chao",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "ZHAO Cong",
                "org": "the Second People's Hospital of Chengdu,Chengdu ,China"
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2008
    },
    "hTcUGQfO": {
        "id": "hTcUGQfO",
        "title": "Static Unbalanced Tensions of Suspension Towers in Medium and Heavy Icing Area",
        "abstract": "During Jan to Feb in 2008,the lasting extreme weather at low temperature for 50 years a meet causes cascade inverting of suspension towers in the the central and southwestern provinces such as Hunan,Jianxi and Zhejiang.It is mainly due to the span and height difference in continuous spans of one strain section and inhomogeneous ice accretion or shedding,which leads to the unbalanced tensions on the two sides of the suspension tower.Computing it needs use three mechanical models and apply programs on MATLAB to analyze the influence of unbalanced tensions and suspention insulators by span,height difference and ice thickness.Therefore,it will prove the ration of raising the percentages about the design of the unbalanced tensions in medium and heavy icing area and offer reference for anti-icing designers and shedding-icing workers of transmission lines.",
        "keywords": [
            "unbalanced tensions",
            "medium and heavy icing area",
            "suspension towers"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "LI Yan-xia",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            },
            {
                "name": "SUN Zi-tang",
                "org": "School of Civil Engineering,Northeast Dianli University,Jilin ,China"
            }
        ],
        "venue": "Central China Electric Power",
        "year": 2011
    },
    "uV30ZiIM": {
        "id": "uV30ZiIM",
        "title": "The Evaluation of Coronary Artery Calcification by Multislice Spiral CT Scan in Hemodialysis Patients and Its Association with Cardiovascular Events",
        "abstract": "Aim To evaluate coronary artery calcification(CAC) by multislice spiral CT scan in patients starting to undergo hemodialysis,and to analyse its association with cardiovascular events in the follow-up. Methods 29 patients starting to undergo chronic hemodialysis(duration of hemodialysis under 6 months) were enrolled in this study.CAC score,along with related parameters,was quantified by Multislice Spiral CT scan at the initiation of this study.The patients were followed up for about 18 months for appraising cardiovascular events. Results 18 cases of CAC(62.07%) were identified by CT scan in 29 patients starting to undergo chronic hemodialysis,with average CAC score being 482.41±739.97.During the 18 months follow-up,significant difference of cardiovascular events was documented among patients with CAC(22 times) and without CAC(1 time)(P=0.001).CAC was independently associated with cardiovascular events(Spearman's Rho=0.882,P<0.0005).Stepwise regression analysis in 29 patients indicated that CAC score was related with age and serum PO4(P=0.013,P=0.043).However,CRP,Ca,iPTH,Chol,TG,HDL-C,LDL-C,BMI,SBP and DBP were excluded from this regression equation(P>0.05). 6 cases(15.79%) were died of cardiovascular events during the 18 months follow-up,including 5 cases with CAC and 1 case without CAC.Kaplan-Meier survival analysis showed that there was no significant difference between patients with CAC and without CAC(P=0.2930). Conclusion Multislice Spiral CT based coronary artery calcification scoring is helpful in risk evaluation of cardiovascular events of hemodialysis patients.",
        "keywords": [
            "Coronary Artery",
            "Calcification",
            "Cardiovascular Events",
            "Hemodialysis"
        ],
        "authors": [
            {
                "name": "ZHANG Bin",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "HE Chao-Sheng",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIANG Xin-Ling",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-Xin",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIN Qiu-Xiong",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "LIANG Yong-Zheng",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            },
            {
                "name": "YE Zhi-Ming",
                "org": "Department of Nephrology & Blood Purification Center,Guangdong General Hospital and Guangdong Academy of Medical Science,Guangzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Arteriosclerosis",
        "year": 2009
    },
    "ikg613F4": {
        "id": "ikg613F4",
        "title": "A new infrared nonlinear crystal - CsGeCl3",
        "abstract": "CsGeCl3 crystal is a new infrared nonlinear crystal. It can be grown from solution. It has higher nonlinear coefficient(about 5 times as that of KDP) and high damage threshold(>200MW/cm2) as well as wide transparency range from 0.38 to 20 μ m.",
        "keywords": [
            "infrared"
        ],
        "authors": [
            {
                "name": "Qingtian Gu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Qiwei Pan",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Wei Shi",
                "org": "Shandong University(Shandong University),Jinan,China"
            },
            {
                "name": "Changshui Fang",
                "org": "Shandong University(Shandong University),Jinan,China"
            }
        ],
        "venue": "Pacific Rim Conference on Lasers and Electro-Optics, CLEO - Technical Digest",
        "year": 2001
    },
    "fOPJ33WG": {
        "id": "fOPJ33WG",
        "title": "Study on a new IR nonlinear optics crystal CsGeCl 3",
        "abstract": "",
        "keywords": [
            "nonlinear optics",
            "frequency doubling",
            "crystal growth",
            "infrared"
        ],
        "authors": [
            {
                "name": "qingtian gu",
                "org": ""
            },
            {
                "name": "qiwei pan",
                "org": ""
            },
            {
                "name": "xiangwen wu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "changshui fang",
                "org": ""
            }
        ],
        "venue": "Journal of Crystal Growth",
        "year": 2000
    },
    "0vWrAuoC": {
        "id": "0vWrAuoC",
        "title": "The Study on the Effect of Warming Yang and Strengthening Spleen Therapy on the Renal Function and Clinical Manifestation of the Rats with Acute Aristolochic Acid Nephropathy",
        "abstract": "Objectives:To investigate the effect of Warming Yang and Strengthening Spleen therapy on the renal function and the clinical manifestations of the rats with acute aristolochic acid nephropathy.Methods:Model group were made into the model of acute aristolochic acid nephropathy by intragastric administration of aristolochiae manshuriensis decoction.The changes of the renal function(BUN;Scr)and the integral calculus of clinical symptoms were observed in every groups.Results:There were the symptoms of spleen-Yang deficiency and significant increase of the BUN,Scr level in rats of the model group(P<0.01);Compared with model group,there were significant reduction of the BUN,Scr level and integral calculus of clinical symptoms in the rats of control group and Chinese Medicine group(P<0.01).Compared with control group,there were significant reduction of the BUN,Scr level and integral calculus of clinical symptoms in the rats of Chinese Medicine group(P<0.05).Conclusions:The rats with acute aristolochic acid nephropathy demonstrate the symptoms of spleen-Yang deficiency.The renal function and the clinical manifestations of the rats with acute aristolochic acid nephropathy could be improved,which suggests the effect of Warming Yang and Strengthening Spleen on the acute aristolochic acid nephropath.",
        "keywords": [
            "Warming Yang and Strengthening Spleen aristolochic acid nephropathy rats kidney function spleen Yang-Deficiency"
        ],
        "authors": [
            {
                "name": "Xie Yongxiang",
                "org": "Nanning Guangxi ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Nanning Guangxi ,China"
            }
        ],
        "venue": "Journal of Sichuan of Traditional Chinese Medicine",
        "year": 2009
    },
    "aAxKPoB2": {
        "id": "aAxKPoB2",
        "title": "k'/k-Dominant Skyline Query over Multiple Time Series",
        "abstract": "Time series have been widely used in many fields of nature and society.And they can be divided into single time series and multiple time series.Multiple time series,consisting of interrelated single time series,can describe an object by many aspects.Therefore,multiple time series are more complex than single time series.At present the research of time series mainly focuses on single time series,and the research of multiple time series is relatively little,such as the query over multiple time series.However,multiple time series are very useful in our life.In addition,most of researches of single time series cannot be used in or extended to multiple time series directly,which makes the study of multiple time series necessary.In this paper we give the definition of the dominant relation between multiple time series,and then propose the k'/k-dominant skyline query over multiple time series.We also present the proof of correctness of algorithms in this paper.Finally a set of experiments are conducted on both synthetic and real data to verify the proposed algorithms.The experiment results prove that both of these two algorithms are effective,and GMI algorithm is much more efficient than GMS.",
        "keywords": [
            "GMI algorithm",
            "GMS algorithm",
            "K'/k-dominant",
            "Multiple time series",
            "Severest ground motion selection method",
            "Skyline query"
        ],
        "authors": [
            {
                "name": "Xu Yajun",
                "org": "School of Software,Tsinghua University,Beijing ;Tsinghua National Laboratory for Information Science and Technology,Beijing ;Key Laboratory for Information System Security(Tsinghua University"
            },
            {
                "name": "Wang Chaokun",
                "org": "School of Software,Tsinghua University,Beijing ;Tsinghua National Laboratory for Information Science and Technology,Beijing ;Key Laboratory for Information System Security(Tsinghua University"
            },
            {
                "name": "Shi Wei",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ;Key Laboratory of Civil Engineering Safety and Durability of China(Tsinghua University"
            },
            {
                "name": "Pan Peng",
                "org": "Department of Civil Engineering,Tsinghua University,Beijing ;Key Laboratory of Civil Engineering Safety and Durability of China(Tsinghua University"
            },
            {
                "name": "DongMei Wei",
                "org": "Tsinghua University(Tsinghua University,Tsinghua Univ,Tsinghua Univ.),Beijing,China"
            }
        ],
        "venue": "Journal of Computer Research and Development",
        "year": 2011
    },
    "BwL1uRuH": {
        "id": "BwL1uRuH",
        "title": "The Design of Residential Quarter's Wireless Parking Barrier by Using ETC Technology",
        "abstract": "In the light of the optional occupation of reserved parking spaces in residential quarter,this paper puts forward an automatically controlled parking lot barrier system,which is equipped with wireless automatic controller keeping the car owners from manually locking and unlocking the parking barriers each time or using the wireless controllers.The tests show that this design can solve intelligently the optional occupation of reserved parking spaces.",
        "keywords": [
            "wireless parking barrier",
            "ETC technology",
            "RSU program"
        ],
        "authors": [
            {
                "name": "LU Xing",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2011
    },
    "CfeiSShm": {
        "id": "CfeiSShm",
        "title": "Study on anti-cracking properties of mass concrete with PCM for temperature control",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Northeast Dianli University Civil Engineering Institute,Jilin ,Jilin,China"
            },
            {
                "name": "ZHANG Xiong",
                "org": "Tongji University Building Material Institute,Shanghai 20009,China"
            }
        ],
        "venue": "New Building Materials",
        "year": 2008
    },
    "N6ZekkYd": {
        "id": "N6ZekkYd",
        "title": "Prospective study of the early diagnosis value for cystatin C in acute renal failure",
        "abstract": "Objective To prospectively study the early diagnosis value of cystatin C in acute renal failure (ARF). Methods One hundred and three critically ill patients hospitalized in intensive care unit were enrolled in the study and blood samples were collected daily. Serum creatinine (Scr) and cystatin C were detected by enzymic method and particle-enhanced turbidimetric immunoassay (PETIA), respectively. Glomerular filtration rate (GFR) was estimated by Cockroft-Gault equation. ARF was diagnosed by RIFLE criteria of ADQI (R: Scr increased by ≥ 50%, I: Scr increased by ≥ 100%, F: Scr increased by ≥200%, L: Loss of kidney function, E:ESRD). Simultaneously, ARF was detected when cystatin C increased by ≥50%, ≥100%, ≥200%. Results Twenty-seven patients (26.2%) developed ARF at different degree, the other 76 cases without ARF were served as control group. During the following up of 27 ARF patients, 15 cases experienced R criteria, 18 cases experienced I criteria, 9 cases experienced R criteria and 3 cases experienced IE criteria. Cystatin C in 27 ARF patients was dramatically increased as compared to that of control group(P < 0.01). Signiflcant linear correlation was found between cystatin C and Scr (r=0.747, P < 0.01), [cystatin C]-1 and estimated GFR(R=0.815, P < 0.01). Diagnostic medium time of ARF by cystatin C and Scr was as following: R criteria of 15 patients 2 days (range 1~4 days)and 3 days(range 2-6 days) (P=0. 011), 1 criteria of 18 patients 4 days(range 1-8 days)and 5.5 days(range 2-10 days) (P=0.006), F criteria of 5 days (range 3-11 days)and 6 days (range 3-13 days) (P=0.02), respectively. ROC analysis confirmed diagnostic accuracy for Cystatin C in ARF, area covered under the AUC curve was 0.995 (95% confidence interval:0.984~1.006)(P<0.001). With the cut-off value of Cystatin C increased ≥ 50%,the diagnostic sensitivity and specificity in ARF were 93% and 96%, respectively. Conclusions Serum cystatin C is superior to serum creatinine as a predictive marker of ARF in an early stage. Cystatin C can be one of the early detection markers of ARF.",
        "keywords": [
            "Diagnosis",
            "Kidney failure",
            "Cystatins C",
            "Prospective study",
            "acute"
        ],
        "authors": [
            {
                "name": "LIANG Xin-ling",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "SHI Wei",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "PENG Yan-qiang",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "ZENG Hong-ke",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "LI Hui",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "ZENG Fang-fang",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "YE Zhi-ming",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            },
            {
                "name": "Wang Wen-jian",
                "org": ". Department of Nephrology, Guangdong Provincial People's Hospital, Guangzhou , China"
            }
        ],
        "venue": "Chinese Journal of Nephrology",
        "year": 2006
    },
    "hvRSgZVs": {
        "id": "hvRSgZVs",
        "title": "Design and Implementation of Wireless Monitoring System Based on Linux socket for Coal",
        "abstract": "It proposes a method which changes the current domestic backward technology status of coal mine safety monitoring,and solves difficulties and problems in coal mine safety monitoring using the advantages of wireless sensor networks in the coal mine safety monitoring,combining with the features of Linux socket's convenient,safe and efficient to.Using ZIGBEE transmission system as a hardware platform,it designs the multi-functional portable wireless sensor nodes for coal mine safety monitoring and the base station sensor nodes.PC uses Socket technology of Linux operating system,sends data into the master site computer,and generates charts to complete system statistics and monitoring.It completely solves a series of technical problems as the bottleneck that conventional RFID monitoring communication distance is limited,not intuitive discrete data which is difficult to provide analysis basis for analysts.The method proposed in this paper has some innovative and practical,and also has important significance for studying for new programs of coal mine safety data collection.",
        "keywords": [
            "node",
            "mine monitoring",
            "base station",
            "Linux socket",
            "Wireless sensor networks"
        ],
        "authors": [
            {
                "name": "LI Lili",
                "org": "School of Electronic and Information Engineering,Liaoning Technical University,Fuxin ,Liaoning"
            },
            {
                "name": "Shi Wei",
                "org": "School of Electronic and Information Engineering,Liaoning Technical University,Fuxin ,Liaoning"
            }
        ],
        "venue": "Computer Measurement & Control",
        "year": 2011
    },
    "YNULuHOA": {
        "id": "YNULuHOA",
        "title": "Ageing reduces the reproductive performance of male white shrimp Litopenaeus vannamei by altering sperm intracellular Ca 2+ concentrations and interfering with sperm apoptosis.",
        "abstract": "Although the effects of age on the reproductive performance of various invertebrates, including white shrimp Litopenaeus vannamei are increasingly well documented, the mechanisms manifesting these impacts remain poorly understood. To ascertain the mechanisms of age on reproductive performance, the sperm quality, intracellular contents of Ca2+, insemination and hatching rates, and status of sperm apoptosis in terms of the expression of key regulatory genes were investigated in 11 and 16 month old male L. vannamei. The aged male individuals (16 months) had lesser reproductive performance in terms of fertilization and hatching rates. In addition, fewer and less viable sperm were detected in aged shrimp, which may be due to the altered expression of apoptosis-related genes. Furthermore, the aged males had lesser intracellular contents of Ca2+ in the sperm which may decrease the capacity of these gametes to undergo a complete acrosome reaction. In general, due to the decrease in intracellular contents of Ca2+ and alterations in the process of apoptosis, aged L. vannamei have relatively lesser quality sperm and may, therefore, have lesser reproductive performance.",
        "keywords": [
            "Litopenaeus vannamei",
            "Age",
            "Ca2+",
            "Reproductive performance"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang Univ, Coll Anim Sci, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "Shanjie Zha",
                "org": "Zhejiang Univ, Coll Anim Sci, Hangzhou, Zhejiang, Peoples R China"
            },
            {
                "name": "Lihua Hu",
                "org": "Mariculture Res Inst Zhejiang Prov, Wenzhou, Peoples R China"
            },
            {
                "name": "Xianke Huang",
                "org": "Mariculture Res Inst Zhejiang Prov, Wenzhou, Peoples R China"
            },
            {
                "name": "Jiongming Zhang",
                "org": "Mariculture Res Inst Zhejiang Prov, Wenzhou, Peoples R China"
            },
            {
                "name": "Maocang Yan",
                "org": "Mariculture Res Inst Zhejiang Prov, Wenzhou, Peoples R China"
            },
            {
                "name": "Guangxu Liu",
                "org": "Zhejiang Univ, Coll Anim Sci, Hangzhou, Zhejiang, Peoples R China"
            }
        ],
        "venue": "ANIMAL REPRODUCTION SCIENCE",
        "year": 2018
    },
    "WFLeEM3b": {
        "id": "WFLeEM3b",
        "title": "Engineering carrier scattering at the interfaces in polyaniline based nanocomposites for high thermoelectric performances",
        "abstract": "We have developed a novel strategy to in situ synthesize water-soluble ternary PANI/SWNT/Te nanocomposites with uniform structures and high thermoelectric (TE) properties. An abnormally high Seebeck coefficient was obtained for the ternary PANI/SWNT/Te nanocomposite films due to the energy filtering effect at the interfaces of PANI/SWNTs and PANI/Te, while the electrical conductivity still remained relatively high. As a result, the TE power factor of the ternary composite films was up to 101 mu W m(-1) K-2, which was much higher than that of the individual components (PANI, SWNTs and Te nanorods). Moreover, a TE module made up of the ternary PANI/SWNT/Te nanocomposite films was fabricated, which was able to generate a high power density of 62.4 mu W cm(-2). Our results reveal a successful approach through designing the nanostructures and energy barriers of ternary nanocomposites to improve the TE properties of PANI.",
        "keywords": "",
        "authors": [
            {
                "name": "Liming Wang",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "MATERIALS CHEMISTRY FRONTIERS",
        "year": 2017
    },
    "02sfte5Z": {
        "id": "02sfte5Z",
        "title": "Identification of thyroid receptor ant/agonists in water sources using mass balance analysis and monte carlo simulation.",
        "abstract": "Some synthetic chemicals, which have been shown to disrupt thyroid hormone (TH) function, have been detected in surface waters and people have the potential to be exposed through water-drinking. Here, the presence of thyroid-active chemicals and their toxic potential in drinking water sources in Yangtze River Delta were investigated by use of instrumental analysis combined with cell-based reporter gene assay. A novel approach was developed to use Monte Carlo simulation, for evaluation of the potential risks of measured concentrations of TH agonists and antagonists and to determine the major contributors to observed thyroid receptor (TR) antagonist potency. None of the extracts exhibited TR agonist potency, while 12 of 14 water samples exhibited TR antagonistic potency. The most probable observed antagonist equivalents ranged from 1.4 to 5.6 µg di-n-butyl phthalate (DNBP)/L, which posed potential risk in water sources. Based on Monte Carlo simulation related mass balance analysis, DNBP accounted for 64.4% for the entire observed antagonist toxic unit in water sources, while diisobutyl phthalate (DIBP), di-n-octyl phthalate (DNOP) and di-2-ethylhexyl phthalate (DEHP) also contributed. The most probable observed equivalent and most probable relative potency (REP) derived from Monte Carlo simulation is useful for potency comparison and responsible chemicals screening.",
        "keywords": [
            "physics",
            "chemistry",
            "gene expression",
            "biology",
            "cell line",
            "china",
            "monte carlo method",
            "biological assay",
            "medicine",
            "geography",
            "computer simulation",
            "engineering"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xin-Xin Hu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Guan-Jiu Hu",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Cu-Lan Chen",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Xin-Ru Wang",
                "org": "Nanjing Medical University(Nanjing Medical University),Nanjing,China"
            },
            {
                "name": "John P Giesy",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hong-Xia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "PloS one",
        "year": 2013
    },
    "e5fAu48N": {
        "id": "e5fAu48N",
        "title": "Enhanced performance and electrocatalytic kinetics of Ni-Mo/graphene nanocatalysts towards alkaline urea oxidation reaction",
        "abstract": "Abstract   Nickel-molybdenum/graphene (Ni-Mo/G) nanocatalysts have been fabricated for alkaline urea electrooxidation. The optimal Ni 2 Mo 1 /G catalysts exhibit fine mesoporous geometric structure (pore size: 3.75 nm, particle size: 20 ∼ 40 nm) and superior electronic structure with richer MoO x  species and Ni 3+  electroactive sites. Owing to the structural/electronic effects, the Ni 2 Mo 1 /G catalysts achieve higher activity and stability (128 mA cm −2  at 0.53 V; 76% retention for 1000 s at 0.50 V) but comparable kinetics (onset potential: 0.39 V; Tafel slope: 120 mV dec −1 ) comparing with the Ni/G nanocatalysts (107 mA cm −2  at 0.51 V; 55% retention for 1000 s at 0.50 V; 0.36 V; 105 mV dec −1 ). Cyclic voltammetry (CV) results reveal the typical catalyst regeneration mechanism (EC’) and diffusion-kinetics mixed processes for the Ni 2 Mo 1 /G catalysts towards alkaline urea electrooxiation, showing the charge transfer coefficient ( α ) and diffusion coefficient ( D ) respective values of 0.73 and 1.11 × 10 −5  cm 2  s −1 . Linear sweep voltammetry (LSV) and Tafel results display the average Tafel slopes (113 mV dec −1 ; 110 mV dec −1 ) and the chemical reaction orders (1.03; 0.60/-0.38/0.32) towards KOH and urea concentrations respectively. Chronoamperometry (CA) results indicate a favorable electrocatalytic endurance by proper Mo doping. The structural/electronic effects tend to produce more Ni 3+  electroactive species and promote the oxidation of urea intermediates via the bi-functional mechanism of the MoO x . The direct urea-hydrogen peroxide fuel cell (DUHPFC) with the Ni 2 Mo 1 /G anode catalysts has also shown superior performance.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            }
        ],
        "venue": "Electrochimica Acta",
        "year": 2017
    },
    "FdpjnZKj": {
        "id": "FdpjnZKj",
        "title": "Research of Electro-Hydraulic Servo Testing Machine Controller Based on ISA Bus",
        "abstract": "A Electro-Hydraulic Servo Testing Machine controller based on DSP and ISA bus is introduced in this paper. Hardware design, DSP and PC software design are introduced in detail. The practical results show that this controller has stable performance and complete function.",
        "keywords": [
            "electro-hydraulic servo",
            "controller",
            "ISA bus"
        ],
        "authors": [
            {
                "name": "Li Jian",
                "org": " Changchun Research Institute for Testing Machine,Jilin Changchun  "
            },
            {
                "name": "Zhang Yong",
                "org": " Changchun Research Institute for Testing Machine,Jilin Changchun  "
            },
            {
                "name": "Shi Wei",
                "org": " Changchun Research Institute for Testing Machine,Jilin Changchun  "
            }
        ],
        "venue": "Test Technology and Testing Machine",
        "year": 2007
    },
    "ZZBkWZod": {
        "id": "ZZBkWZod",
        "title": "Prehistory Sites and Environmental Characteristics in The Three Gorges Region",
        "abstract": "Having observed the sites in Zhongba, Yuxi, Wachadi and Xiaopengzui etc. in The Three Gorges Region, combined with the researches of the forefathers, the following knowledge is found; (1) The types of sites mainly include the residences and salt sites; (2) The sites are restrained by natural conditions with obvious secondary structure; (3) Because of the characteristics of the regional environmental condition, fishing and hunting in The Three Gorges Region were more advantageous than planting.",
        "keywords": [
            "The Three Gorges Region",
            "cultural sequences",
            "types of sites",
            "environmental condition",
            "prehistory"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " Department of Geography, Jiangsu Institute of Education, Nanjing, ; Institute of Oceanology & Geography Sciences, Nanjing University, Nanjing, "
            },
            {
                "name": "ZHANG Jing",
                "org": " Nanhu Middle School in Nanjing City, Nanjing, "
            }
        ],
        "venue": "Journal of Jiangsu Institute of Education(Natural Sciences)",
        "year": 2008
    },
    "F12iArgA": {
        "id": "F12iArgA",
        "title": "Low serum fetuin A is a risk factor of coronary artery calcification in patients starting hemodialysis]",
        "abstract": "To examine the relationship between reduction of serum fetuin A and coronary artery calcification (CAC) in patients starting hemodialysis.Twenty-nine patients on chronic hemodialysis (duration of hemodialysis less than 6 months) were enrolled in this study. Serum fetuin A and such potential CAC-related risk factors as C-reactive protein (CRP), Ca, P, iPTH, body mass index (BMI) were examined. CAC was detected by multislice spiral CT scan (MSCT) and quantified by the modified Agaston's scoring system. All the 29 patients were followed up for 18 months to appraise the cardiovascular events defined as cardiac failure, angina pectoris or myocardial infarction.Eleven patients (78.57%) were found to have CAC as detected by MSCT in low serum fetuin A (below the average serum concentration of 0.71 g/L) group, a rate significantly higher than that in high serum fetuin A group (7 patients, 46.67%, P<0.05). Serum fetuin A in these 29 patients was related with CAC score (Pearson correlation coefficient of -0.734, P=0.001) and stepwise regression analysis indicated that serum fetuin A (standardized beta=-0.568, P=0.003) and age (standardized beta=0.416, P=0.019) were independently correlated to CAC. Such factors as CRP, Ca, P, iPTH, Chol, TG, HDL-C, LDL-C, BMI and blood pressure were excluded from the regression equation. Reduction of serum fetuin A was associated with cardiovascular events (Spearman's rho -0.758, P<0.01). No significant difference was found between low and high serum fetuin A groups by Kaplan-Meier survival analysis (P=0.065).Reduced serum fetuin A may be a potential risk factor of coronary artery calcification, and can contribute to cardiovascular events in patients starting hemodialysis.",
        "keywords": [
            "fetuin a",
            "calcification",
            "hemodialysis",
            "coronary artery"
        ],
        "authors": [
            {
                "name": "Bin Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China;Southern Medical University, Guangzhou , China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China;Southern Medical University, Guangzhou , China"
            },
            {
                "name": "Chao-sheng He",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China"
            },
            {
                "name": "Xing-ling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China"
            },
            {
                "name": "Shuang-xin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China"
            },
            {
                "name": "Yong-zheng Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangzhou , China"
            }
        ],
        "venue": "Nan fang yi ke da xue xue bao = Journal of Southern Medical University",
        "year": 2010
    },
    "TGIv82Oe": {
        "id": "TGIv82Oe",
        "title": "Photoluminescence Spectra of Porous Silicon- polymer PFTD Composite Films",
        "abstract": "In the paper,red-emitting polymer(PFTD) film was coated onto the surface of porous silicon(PSi).The photoluminescence of PSi,PFTD/PSi,PFTD/Si,and PFTD in toluene was investigated.The experiment results showed that the luminescence intensity of PFTD/PSi was higher than PFTD/Si.Compared with PFTD in toluene and PFTD/Si,the photoluminescence spectra of PFTD/PSi showed a red shift,which were attributed to enhancement of conjugate of polymer in solid state.",
        "keywords": [
            "PFTD",
            "photoluminescence",
            "porous silicon",
            "red-emitting polymer"
        ],
        "authors": [
            {
                "name": "Mo Jiaqing",
                "org": "College of Information Science and Technology,Xinjiang University,Urumqi,"
            },
            {
                "name": "Shi Wei",
                "org": "Key Laboratory of Petroleum and Gas Fine Chemicals,Educational Ministry,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "Lv Xiaoyi",
                "org": "College of Information Science and Technology,Xinjiang University,Urumqi,"
            }
        ],
        "venue": "Guangdong Chemical Industry",
        "year": 2012
    },
    "H6oUmufX": {
        "id": "H6oUmufX",
        "title": "Mechanisms of gene rearrangement in 13 bothids based on comparison with a newly completed mitogenome of the threespot flounder, Grammatobothus polyophthalmus (Pleuronectiformes: Bothidae).",
        "abstract": "The mitogenomes of 12 teleost fish of the bothid family (order Pleuronectiformes) indicated that the genomic-scale rearrangements characterized in previous work. A novel mechanism of genomic rearrangement called the Dimer-Mitogenome and Non-Random Loss (DMNL) model was used to account for the rearrangement found in one of these bothids, Crossorhombus azureus. The 18,170 bp mitogenome of G. polyophthalmus contains 37 genes, two control regions (CRs), and the origin of replication of the L-strand (OL). This mitogenome is characterized by genomic-scale rearrangements: genes located on the L-strand are grouped in an 8-gene cluster (Q-A-C-Y-S1-ND6-E-P) that does not include tRNA-N; genes found on the H-strand are grouped together (F-12S … CytB-T) except for tRNA-D that was translocated inside the 8-gene L-strand cluster. Compared to non-rearranged mitogenomes of teleost fishes, gene organization in the mitogenome of G. polyophthalmus and in that of the other 12 bothids characterized thus far is very similar. These rearrangements could be sorted into four types (Type I, II, III and IV), differing in the particular combination of the CR, tRNA-D gene and 8-gene cluster and the shuffling of tRNA-V. The DMNL model was used to account for all but one gene rearrangement found in all 13 bothid mitogenomes. Translocation of tRNA-D most likely occurred after the DMNL process in 10 bothid mitogenomes and could have occurred either before or after DMNL in the three other species. During the DMNL process, the tRNA-N gene was retained rather than the expected tRNA-N′ gene. tRNA-N appears to assist in or act as OL function when the OL secondary structure could not be formed from intergenic sequences. A striking finding was that each of the non-transcribed genes has degenerated to a shorter intergenic spacer during the DMNL process. These findings highlight a rare phenomenon in teleost fish. This result provides significant evidence to support the existence of dynamic dimeric mitogenomes and the DMNL model as the mechanism of gene rearrangement in bothid mitogenomes, which not only promotes the understanding of mitogenome structural diversity, but also sheds light on mechanisms of mitochondrial genome rearrangement and replication.",
        "keywords": [
            "Flatfish",
            " Bothidae",
            " Mitogenome",
            " Rearrangement mechanism",
            " Dimeric mitogenomes",
            " Intergenic spacer"
        ],
        "authors": [
            {
                "name": "Hairong Luo",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Guangzhou, China"
            },
            {
                "name": "Xiaoyu Kong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Guangzhou, China"
            },
            {
                "name": "Shixi Chen",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Guangzhou, China"
            },
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Guangzhou, China"
            }
        ],
        "venue": "BMC Genomics",
        "year": 2019
    },
    "hdLpQKfY": {
        "id": "hdLpQKfY",
        "title": "A Study on Load Evaluation and Analysis for Foundation of the Offshore Wind Turbine System",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "daeyong kwon",
                "org": ""
            },
            {
                "name": "hyunchul park",
                "org": ""
            },
            {
                "name": "chinwha chung",
                "org": ""
            },
            {
                "name": "yongchun kim",
                "org": ""
            },
            {
                "name": "seungmin lee",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2010
    },
    "wCBmffMX": {
        "id": "wCBmffMX",
        "title": "Modern Knowledge Philosophy Viewed from the Logic of the Western Philosophy",
        "abstract": "Modern philosophy is celebrated for knowledge.It feels,in fact incorrect of the ossification giving person at first glance always one kind of basis doctrine,nature doctrine,soul poured being moving by the mother's body digging modern philosophy deep,from the inside that development of entire west philosophy to inspect with the logic,in it deeply longing for having embodied life,liberty and value to person.How to reveal west modern philosophy is the course running after significance,entirely understand inherent west philosophy logic or not thought west philosophy is that a volume has important significance unceasingly to open history of person with have the nothing significance or not,very good assurance.",
        "keywords": [
            "the inherent logic",
            "knowledge comment",
            "the modern philosophy"
        ],
        "authors": [
            {
                "name": "HAN Qiu-hong",
                "org": "School of Politics and Laws,Northeast Normal University,Changchun ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Politics and Laws,Northeast Normal University,Changchun ,China"
            }
        ],
        "venue": "Journal of Northeast Normal University(Philosophy and Social Sciences)",
        "year": 2007
    },
    "WSZpfnvF": {
        "id": "WSZpfnvF",
        "title": "Synthesis and Characterization of Conjugated Copolymers of p-Benzoquinone Diimine and p-Phenyleneethylene by Metal Complexes Catalyzed Polymerization",
        "abstract": "Under the presence of metal complex,poly(N,N′-p-benzoquinone diimine-alt-1,4-diethynyl-2,5-bis(n-alkoxy) benzene(PAn-PPE) was synthesized via cross coupling reaction between the N,N′-dich-loro-p-benzoquinone diimine and 1,4-diethynyl-2,5-bis(n-alkoxy) benzene,which was characterized by FT-IR、1H-NMR、GPC、XRD、UV-Vis、PL and TGA.Results show that UV-Vis maximum absorption wavelength of PAn-PPE in THF and TFA is about 440 nm and 490 nm respectively.The photoluminescence excitation and emission peak are about 450 nm and 475 nm,respectively.The copolymers have good electrochemical activities and thermal stability.",
        "keywords": [
            "p-benzoquinone diimine",
            "alternative copolymerization",
            "p-phenyleneethylene"
        ],
        "authors": [
            {
                "name": "ZHANG Jian-ping",
                "org": "Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            },
            {
                "name": "LI Juan-juan",
                "org": "Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education,School of Chemistry and Chemical Engineering,Xinjiang University,Urumqi ,China"
            }
        ],
        "venue": "Journal of Functional Polymers",
        "year": 2011
    },
    "8lkucIPK": {
        "id": "8lkucIPK",
        "title": "Fabrication of 4×4 tapered MMI coupler with large cross section",
        "abstract": "MMI coupler with large cross section has low coupling loss between the device and fiber. However, large chip area is required. Recently proposed N/spl times/N tapered MMI coupler shows a substantial reduction in device geometry. No such kind of devices with N>2 has yet been realized up to now. The authors have demonstrated a 4/spl times/4 parabolically tapered MMI coupler with large cross section ...",
        "keywords": [
            "Fabrication",
            "Silicon on insulator technology",
            "Optical fiber couplers",
            "Optical fiber devices",
            "Integrated circuit technology",
            "Geometry",
            "Coupling circuits",
            "Samarium",
            "Optical losses",
            "Integrated optics"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Inst. of Semicond., Acad. Sinica, Beijing, China"
            },
            {
                "name": "Jinzhong Yu",
                "org": ""
            },
            {
                "name": "Zhongli Liu",
                "org": ""
            },
            {
                "name": "Xiaofeng Zhang",
                "org": "Institut fur Informatik"
            },
            {
                "name": "Wei Shi",
                "org": "E.E. Dept"
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "IEEE Photonics Technology Letters",
        "year": 2001
    },
    "isJvGGcs": {
        "id": "isJvGGcs",
        "title": "Hierarchical mesoporous Ni-P@MnO2 composite for high performance supercapacitors",
        "abstract": "Abstract   Hierarchical mesoporous Ni-P@MnO 2  composite has been synthesized by solvothermal fabrication of Ni-P and subsequent chemical deposition of MnO 2 . Owing to the synergistic effect between Ni-P and MnO 2 , the Ni-P@MnO 2  composite exhibits a superior specific capacitance and rate capability (1130 F g −1  at 1 A g −1 , 352 F g −1  at 16 A g −  1 ) compared with the bare Ni-P materials. Furthermore, the AC//Ni-P@MnO 2  asymmetric capacitor outdoes the AC//Ni-P asymmetric capacitor, exhibiting high energy/power densties of 10.9 Wh kg −1 /5.6 kW kg −  1  with excellent cycling behavior (no decay after 10,000 cycles at 2 A g −1 ). The high performance makes the hierarchical mesoporous Ni-P@MnO 2  composite promising electrode materials for supercapacitors.",
        "keywords": "",
        "authors": [
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Luo Wang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Haxia Jiang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Zeng Yang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2017
    },
    "m0WA3erj": {
        "id": "m0WA3erj",
        "title": "Harmonious wisdom and sapiential harmony——be upper in the thought of \"Number\" primitive in Pythagoras",
        "abstract": "\"Number\" primitive thought of Pythagoras is all things on earth's harmoniously with harmonious number superficial characteristics,with the number wisdom superficial characteristics the universe wisdom,philosophy expounds and proves by the fact that \"what the wisdom \"—\"Number \",\"what finest\"——\"harmonious\",have reached each other harmonious wisdom of truth ,good and beauty ,give philosophy to the beginning of plain's ,this true significance \"Philosophy \".",
        "keywords": [
            "\"number\"Primitive",
            "wisdom",
            "harmonious"
        ],
        "authors": [
            {
                "name": "HAN Qiu-hong",
                "org": "Northeast Normal University politics and law academy"
            },
            {
                "name": "Shi Wei",
                "org": "Northeast Normal University politics and law academy"
            }
        ],
        "venue": "The Northern Forum",
        "year": 2008
    },
    "zIcUUFCa": {
        "id": "zIcUUFCa",
        "title": "Investigation of the polyetherketone guest–host DR1/PEK-c polymer films by real-time monitoring of the second-harmonic generation",
        "abstract": "The real-time monitoring of the second-harmonic generation (SHG) was used to optimize the poling condition and to study the nonlinear optical (NLO) properties of the polyetherketone (PEK-c) guest–host polymer films. The high second-order NLO coefficient χ 33 (2) =11.02 pm/v measured at 1.064 μm was achieved when the weight percent of DR1 guest in the polymer system is 20%. The NLO activity of the poled DR1/PEK-c polymer film can maintain more than 80% of its initial value when temperature is under 100°C, and the normalized second-order NLO coefficient can maintain more than 85% after 2400 s at 80°C. Keywords Polymer films Second-harmonic generation Poling Nonlinear optical coefficient 1 Introduction The development of thin film polymer materials that are suitable for the fabrication of high-speed integrated optical devices is presently a major focus of research in nonlinear optics [1–3] . Polymer materials have been demonstrated to possess large NLO activity compared to traditional inorganic materials, and the intrinsic low dielectric constant, ease of processing into thin films and compatibility with microelectronic processes are the other major advantages of the polymers. Significant progress in device design and architecture with implementation of poled polymers into prototype electro-optical devices has been reported recently [4,5] . However, the unpoled NLO polymer is isotropic, i.e. the orientational distribution of NLO chromophores in the unpoled polymer films is isotropic. The corona-onset poling at elevated temperature (COPET) is a favored technique for producing noncentrosymmetric NLO polymeric films [6] . The NLO activity of poled polymers originated from the chromophores that exhibit a strong NLO effect and from the angular alignment of these chromophores by electric field poling. So, highly efficient poling is necessary to realize large NLO activity. The COPET generally involves heating the NLO polymer to just below its glass transition temperature ( T g ), applying a large electric field to orient the chromophore molecules, and cooling the NLO polymer while the field is still applied. In this paper, the optimal poling temperature and poling time at this temperature were derived by means of well-controlled corona poling with in situ SHG signal intensity probing, and the high second-order NLO coefficient χ (2) 33 =11.02 pm/v (at 1.064 μm) was achieved for the DR1/PEK-c guest–host polymer film. Furthermore, the temporal and temperature stability of the polymer system was demonstrated by in situ SHG signal intensity measurements. 2 Experiments and results The host polymer PEK-c is a highly transparent polymer with high glass transition temperature T g ∼228°C. It is an ideal polymer host for device fabrication because it is mechanically strong, easily processed into low optical loss thin films, and thermally stable up to 400–500°C. The DR1 is a common chromophore, but its guest–host polymer systems are always used for fabricating polymer waveguide devices. DR1 and PEK-c were dissolved in 1,2-dichlorethane, respectively. When guest DR1 and host PEK-c were wholly dissolved in 1,2-dichlorethane, they were mixed together. Then pre-mixed solution was filtered through a syringe with a 0.2 μm filter attached. The final polymer solution can be easily spin coated onto ITO glass substrates to form polymer thin films such that the doped concentration of DR1 in polymer system is 20%. Then the films were cured at 80°C for several hours to remove the residual solvent. The schematic drawing of the experimental set-up for in situ SHG signal intensity measurement is shown in Fig. 1 . The polarized beam of a Q-switched Nd-YAG laser ( λ =1.064 μm) was focused onto the sample with an angle of incidence of 45°. A tungsten needle was located about 1.5 cm above the sample. The fundamental wave was blocked by high-pass filters and a 532 nm-interference filter. The SHG signal was detected by a photomultiplier tube then amplified and averaged in a boxcar integrator. The boxcar output was registered by a microcomputer. Fig. 2 shows in situ SHG signal intensity ( I 2 ω ) profile with the poling temperature increasing (the rate of temperature increase is 5°C/min). When temperature is under 140°C, the SHG signal intensity is very small except a low peak at nearly 85°C (the reason will be analyzed in another paper). When temperature is above 140°C, the SHG signal intensity increases rapidly because more chromophores in the polymer film are oriented along the electric field due to the greater mobility of the polymer at this temperature. But the SHG signal intensity decreases quickly when temperature is above 155°C which can be regarded as a critical temperature [7] . The following are the main reasons to explain this decrease of the SHG signal intensity when temperature is beyond the critical temperature. The chromophores in the guest–host polymer system would sublimate and crystallize (or aggregate) at this high temperature [8] . The dramatic increment of conductivity of the polymer film can occur at this temperature, and results in the decrease of the effective electric field strength in the polymer film [9] . So, the optimal poling temperature for this polymer system can be determined as 150°C which is lower than its glass transition temperature 168°C measured by DSC (this glass transition temperature is lower than that of pure PEK-c polymer because of the plasticization induced by DR1 guest). From experiments, the optimal poling voltage applied to the tungsten needle is 6 kV for the investigated polymer system. Fig. 3 shows the poling time dependence of the SHG signal intensity at 150°C (poling voltage is 6 kV). From Fig. 3 , we can see that the SHG signal intensity can reach saturation in a short period of about 300 s. When the poling time passes beyond 300 s at 150°C, the SHG signal intensity decreases gradually due to the sublimation, aggregation, decomposition and oxidation of the chromophores in the polymer films. This means that the orientation of the chromophores in the polymer films induced by electric field can be fulfilled in a short period of time at 150°C. So the optimal poling time can be derived as 300 s at 150°C. According to the above optimal poling conditions, the polymer films were poled at 150°C with COPET by applying 6 kV voltage to the tungsten needle located 1.5 cm above thin films. After poling for 300 s at 150°C, the sample was cooled to room temperature while maintaining the poling voltage unchanged. The second-order NLO coefficient χ (2) 33 of the poled polymer film was 11.02 pm/v measured with Maker fringe method [10] . The refractive index was measured by using prism–coupler waveguide method [11] . The temperature stability of the poled polymer film was measured by probing the SHG signal intensity with temperature increasing at a rate of 5°C/min. The in situ measurement of NLO response for the poled film as a function of temperature is shown in Fig. 4 . The poled film shows a good temperature stability of NLO activity. The NLO activity undergoes very small decay for temperature below 80°C, and maintains approximately 80% of the initial value at 100°C and approximately 50% at 125°C. When temperature is above 150°C, there is almost no SHG signal intensity because of the reorientation of the chromophores in the polymer host that has greater mobility at this temperature. In order to test the temporal stability of the poled polymer film, the SHG signal intensity was measured after the sample was heated isothermally at 80°C over a period. Fig. 5 shows the time dependence of I 2ω (t)/I 2ω (0) , where I 2 ω ( t ) is the SHG signal intensity at time t as a function of time at 80°C and I 2 ω (0) is its initial value. Since the normalized second-order NLO coefficient χ (2) 33 (t)/χ (2) 33 (0)= I 2ω (t)/I 2ω (0) , the decay of the second-order NLO coefficient is represented in Fig. 5 [12] . It is obvious that there is little relaxation of the NLO activity for the investigated guest–host polymer film at 80°C. The NLO activity can maintain more than 85% of its initial value after 2400 s at 80°C. The orientational relaxation phenomena of the NLO activity can be empirically described by Kohlrausch–Williams–Watts (KWW) stretched exponential function [13,14] (1) χ (2) 33 (t) χ (2) 33 (0) = I 2ω (t) I 2ω (0) = exp − t τ β . where τ is the characteristic time of relaxation and β is a constant between 0 and unity, describing the deviation from the ideal exponential decay process. In fitting our data with this approach, we plotted ln{−ln[ χ (2) 33 ( t )/ χ (2) 33 (0)]} against ln( t ). From the intercept and slope of the fitting line, we obtain the values of β =0.31705 and τ =1392310 s. Another alternative for fitting the experimental data is a biexponential function [15,16] (2) χ (2) 33 (t) χ (2) 33 (0) = I 2ω (t) I 2ω(0) =A 1 exp − t τ 1 +A 2 exp − t τ 2 . where A 1 + A 2 =1, τ 1 and τ 2 are the short and long characteristic relaxation times extracted from the biexponential fitting and are 125 and 1886 s, respectively. The corresponding values of A 1 and A 2 from the fitting are 0.33 and 0.67, respectively. From the two fitting lines in Fig. 5 , it is found that KWW-stretched exponential function produces a better fitting result than the biexponential function. 3 Conclusions By the in situ SHG signal intensity measurement, the optimal poling condition can be achieved. For the investigated DR1/PEK-c polymer film, the optical poling temperature, time, and voltage are 150°C, 300 s and 6 kV, respectively. Under this optimal poling condition, the high second-order NLO coefficient χ 33 (2) =11.02 pm/v has been obtained for the PEK-c polymer film doped DR1 by weight percent of 20%. The DR1/PEK-c guest–host polymer system has good temporal and temperature stability of NLO activity. The SHG signal intensity can maintain more than 80% of its initial value when temperature is under 100°C, and the normalized second-order NLO coefficient can maintain more than 85% after 2400 s at 80°C. The temporal stability of the NLO activity of poled DR1/PEK-c polymer film can be better fitted by KWW-stretched exponential function than the biexponential function. Acknowledgements We gratefully acknowledge the National Natural Science Foundation of China (Grant No. 69990540). References [1] D.M. Burland R.D. Miller C.A. Walsh Second-order nonlinearity in poled-polymer systems Chem Rev 94 1 1994 31 75 [2] S.M. Marder B. Kippelen A.K.Y. Jen Peyghambarian N. Design and synthesis of chromophores and polymers for electro-optic and photorefractive applications Nature 388 1997 845 851 [3] R.H. Page M.C. Jurich B. Reck A. Sen R.J. Twieg J.D. Swalen G.C. Bjorklund C.G. Willson Electrochromic and optical waveguide studies of corona-poled electro-optic polymer films J Opt Soc Am B 7 7 1990 1239 1250 [4] L.R. Dalton Polymeric electro-optic modulators Chem Ind 7 1997 510 514 [5] A. Chen V. Chuyanov S. Garner H. Zhan W.H. Steier J. Chen Low- V π electro-optic modulator with a high- μβ chromophore and a constant-bias field Opt Lett 23 6 1998 478 480 [6] M.A. Mortazavi A. Knoesen S.T. Kowel B.G. Higgins A. Dienes Second-harmonic generation and absorption studies of polymer-dey films oriented by corona-onset poling at elevated temperatures J Opt Soc Am B 6 4 1989 733 741 [7] Q.M. Tao Z.J. Hou L.Y. Liu Optical nonlinearity study of poled cyano-group modified phenylhydrazone doped polymer films Acta Opt Sinica 19 5 1999 672 676 [8] A.W. Harper S. Sun L.R. Dalton S.M. Garner A. Chen S. Kalluri Translating microscopic optical nonlinerity into macroscopic optical nonlinearity: the role of chromophore-chromophore electrostatic interactions J Opt Soc Am B 15 1 1998 329 337 [9] R. Blum M. Sprave J. Sablotny M. Eich High-electric-field poling of nonlinear optical polymers J Opt Soc Am B 15 1 1998 318 328 [10] M. Eich H. Looser Y.D. Yoon R. Twieg G. Bjorklund J.C. Baumert Second-harmonic generation in poled organic monomeric glass J Opt Soc Am B 6 8 1989 1590 1597 [11] Q. Ren Z. Wang S. Guo D. Xu S. Shang Thickness and dielectric property of PT-PEK-c electrooptic polymer film Acta Photonica Sinica 26 12 1997 1115 1118 [12] M.M. Stähelin D. Burland M.M. Ebert R.D. Miller B.A. Smith R.J. Twieg Re-evaluation of the thermal stability of optically nonlinear polymeric guest–host systems Appl Phys Lett 61 14 1992 1626 1628 [13] M.G. Kuzyk R.C. Moor L.A. King Second harmonic-generation measurement of the elastic constant of a molecule in a polymer matrix J Opt Soc Am B 7 1990 64 72 [14] K. Singer L. King Relaxation phenomena in polymer nonlinear optical-materials J Appl Phys 70 1991 3251 3255 [15] H. Hampsch J.M. Torkelson J. Yang G.K. Wang Second harmonic-generation in doped glass polymer-films as a function of physical aging and dopant size Polymer Commun 30 1989 40 43 [16] C.P.J.M. Vorst R.A.P. Gassel Thermal relaxation of poled nonlinear optical sidechain polymers: a new, semi-empirical model Macromol Symp 90 1994 47 64",
        "keywords": [
            "second harmonic generation",
            "nonlinear optics",
            "second order"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Zhiling Xu",
                "org": "State Key Laboratory For Materials Modification by Laser, Ion and Electron Beams, Department of Physics, Fu Dan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hongzhen Wei",
                "org": "Institute of Semiconductors, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Optics and Lasers in Engineering",
        "year": 1999
    },
    "Kbwg3Yvr": {
        "id": "Kbwg3Yvr",
        "title": "Bimetallic Co-Mn Perovskite Fluorides as Highly-Stable Electrode Materials for Supercapacitors.",
        "abstract": "Bimetallic Co-Mn perovskite fluorides (KCo Mn F , denoted as K-Co-Mn-F) with various Co/Mn ratios (1:0, 12:1, 6:1, 3:1, 1:1, 1:3, 0:1) were prepared through a one-pot solvothermal strategy and further used as electrode materials for supercapacitors. The optimal K-Co-Mn-F candidate (Co/Mn=6:1) showed a size range of 0.1-1 μm and uniform elemental distribution; exhibiting small changes in XRD peaks and XPS binding energy in comparison to the bare K-Co-F and K-Mn-F, due to the structural/electronic effects. Owing to the stronger synergistic effect of Co/Mn redox species, the K-Co-Mn-F (Co/Mn=6:1) electrode exhibited superior specific capacity and rate behavior (113-100 C g at 1-16 Ag ) together with excellent cycling stability (118 % for 5000 cycles at 8 Ag ), and the activated carbon (AC)//K-Co-Mn-F (Co/Mn=6:1) asymmetric capacitor showed superior energy and power densities (8.0-2.4 Wh kg at 0.14-8.7 kW kg ) along with high cycling stability (90 % for 10 000 cycles at 5 Ag ).",
        "keywords": [
            "cobalt",
            "manganese",
            "perovskite fluorides",
            "solvothermal reactions",
            "supercapacitors"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Danfeng Ying",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Yongfa Huang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, P.R. China."
            }
        ],
        "venue": "Chemistry (Weinheim an der Bergstrasse, Germany)",
        "year": 2017
    },
    "6aszToQJ": {
        "id": "6aszToQJ",
        "title": "Study on the lightning intruding over-voltage in 750 kV GIS substation",
        "abstract": "There are many factors affecting the lightning intruding over-voltage in substation, except impulse corona and the tower model, the mode and length of GIS outgoing line are also the factors. On the basis of the Q-V characteristics of transmission lines, in this paper, a simple circuit model is presented to simulate characteristics of corona on the transmission lines, and the effect of corona on lightning over voltage has been studied. Three tower models that are lumped inductance model, single surge impedance model and multi-surge impedance model, are built, and the effect of tower model on lightning over voltage has been studied. Considering the influence of every factor, through two types of lightning stroke, that is lightning stroke on the top of a tower and shielding failure, the lightning over-voltages on circuit breaker(CB), current transformer(CT) and transformer are calculated by EMTP when lightning waves intrude into 750kV GIS substation in this paper. The study indicates that corona makes lightning intrusive wave attenuated and distorted greatly, so the amplitude and gradient of lightning wave are reduced greatly, the attenuation in the section of ingoing line caused by corona takes up about 5% of the total lightning over voltage. Among three tower models, the over voltage derived from lumped inductance model is bigger than that derived from single surge impedance model, and the over voltage derived from single surge impedance model is bigger than that derived from multi-surge impedance model. The discrepancy between three models is nearly 10%.",
        "keywords": [
            "GIL",
            "GIS",
            "Impulse corona",
            "Lightning intruding over-voltage",
            "Tower model"
        ],
        "authors": [
            {
                "name": "Liangjin Chen",
                "org": "Zhejiang Electric Power Test and Research Institute(Zhejiang Electric Power Test and Research Institute),Hangzhou,China"
            },
            {
                "name": "Sinan Li",
                "org": "Zhejiang Electric Power Test and Research Institute(Zhejiang Electric Power Test and Research Institute),Hangzhou,China"
            },
            {
                "name": "Peng Xie",
                "org": "Guangdong Grid Corporation(Guangdong Grid Corporation),,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            }
        ],
        "venue": "Gaodianya Jishu/High Voltage Engineering",
        "year": 2006
    },
    "sbN5fVDc": {
        "id": "sbN5fVDc",
        "title": "Distribution Characteristics of Chinese Medicine Symptoms in Diabetic Nephropathy and Its Relationship with Serum Fibrosis Factors",
        "abstract": "Objective To investigate the distribution characteristics of traditional Chinese medicine symptoms in diabetic nephropathy(DN) and its relationship with serum fibrosis factors including type Ⅲ collagen fiber(CoL-Ⅲ),type Ⅳ collagen fiber(CoL-Ⅳ) and Laminin(LN).Methods The clinical stages and syndrome type of traditional Chinese medicine were described in 360 patients with diabetic nephropathy by means of statistics,and enzyme-linked immunosorbent assay was performed to detect the level of CoL-Ⅲ,CoL-Ⅳ and LN.Results There were 136 DN patients in stage Ⅲ,144 patients in stage Ⅳ,and 80 patients in stage Ⅴ.Patients with syndrome type of traditional Chinese medicine in stage Ⅲ mainly showed Yin deficiency of liver and kidney,while patients in stage Ⅳ mainly showed deficiency of Qi and Yin,and patients in stage Ⅴ showed Yang deficiency of spleen and kidney.There was the law of development from Yin deficiency to dual deficiency of Qi and Yin,then to deficiency of Yang in traditional Chinese medicine symptoms in DN patients.The levels of CoL-Ⅲ,CoL-Ⅳ and LN increased in DN patents in each stage(P<0.05);The increase was highest in patients in stage Ⅲ,but lowest in patients in stage Ⅴ(P<0.05).Conclusion Diabetic nephropathy develops according to the law from Yin deficiency to dual deficiency of Qi and Yin,then to deficiency of Yang.Sacrificial traditional Chinese medicine symptoms in diabetic nephropathy is dominated by blood stasis and damp-turbidity symptoms.The levels of CoL-Ⅲ,CoL-Ⅳ and LN are not only regarded as the early diagnosis indices of DN,but also have certain significance for judgement of DN stage,severity of disease and prognosis.",
        "keywords": [
            "Traditional Chinese medicine symptom",
            "Serum fibrosis factor",
            "Diabetic nephropathy"
        ],
        "authors": [
            {
                "name": "WU Jin-yu",
                "org": " Department of Nephrology,the First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "HUANG Ren-fa",
                "org": " Department of Nephrology,Affiliated Ruikang Hospital,Guangxi University of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephrology,the First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "HUANG Xue-xia",
                "org": " Department of Nephrology,the First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "TANG Yu",
                "org": " Department of Nephrology,the First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine,Nanning ,China"
            },
            {
                "name": "LAI Shen-chang",
                "org": ""
            }
        ],
        "venue": "Guangxi Medical Journal",
        "year": 2012
    },
    "qTyKqocF": {
        "id": "qTyKqocF",
        "title": "The Investigation on Managers' Time Management Disposition and Self-worth",
        "abstract": "The Time Management Disposition Scale and Self-Worth Scale were used to investigate 256 managers in Chongqing.The results showed: 1) Private enterprise managers' time monitor and time efficacy were apparently higher than public enterprise managers'.Time monitor and time efficacy were influenced by the degree of education.2) Private enterprise managers' general self-worth and special self-worth were evidently higher than public enterprise managers',but there was no difference in global self-worth and no gender-difference.The three levels of self-worth were affected by the degree of education.3) The three dimensions of time management disposition had a positive correlation with global self-worth,general self-worth and special self-worth.Especially,time efficacy was an evidently predictive variable to the three levels of self-worth.",
        "keywords": [
            "time management disposition",
            "managers",
            "self-worth"
        ],
        "authors": [
            {
                "name": "Lu Lin",
                "org": "College of Management,Southwest University,Chongqing,"
            },
            {
                "name": "Shi Wei",
                "org": "College of Management,Southwest University,Chongqing,"
            }
        ],
        "venue": "Psychological Science",
        "year": 2006
    },
    "QUBtHsYe": {
        "id": "QUBtHsYe",
        "title": "Dissolution of Calcite at Up to 250 °C and 1450 bar and the Presence of Mixed Salts",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "mason b tomson",
                "org": ""
            },
            {
                "name": "nan zhang",
                "org": ""
            },
            {
                "name": "amy t kan",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "Industrial & Engineering Chemistry Research",
        "year": 2013
    },
    "0DKQR3KG": {
        "id": "0DKQR3KG",
        "title": "A tri-site fluorescent probe for simultaneous sensing of hydrogen sulfide and glutathione and its bioimaging applications.",
        "abstract": "Hydrogen sulfide (H2S) and biothiol molecules, such as glutathione (GSH), cysteine (Cys), and homocysteine (Hcy), play an important role in biology. However, understanding the complicated relationship between H2S and biothiols remains an enormous challenge owing to the difficulty in sensing H2S and biothiols simultaneously. Therefore, the development of probes for detecting H2S and biothiols is of great importance in biological science. In this work, we reported a novel fluorescent probe for the sensitive and selective detection of H2S and glutathione (GSH) simultaneously in different buffer solutions. The key design principle is based on a coumarin as the fluorophore structuring a fluorescent probe with three potential sites which could react with H2S and biothiols. This probe displays a rapid response with highly sensitive and selective detection of H2S and GSH (the detection limit of 75 nM and 280 nM, respectively). Moreover, with the assistance of a confocal fluorescence microscope, we demonstrated that the probe can be successfully applied for imaging H2S and GSH in MCF-7 cells.",
        "keywords": "",
        "authors": [
            {
                "name": "Fengzao Chen",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Deman Han",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Heng Liu",
                "org": "Hubei Univ, Coll Chem & Chem Engn, Wuhan 430062, Hubei, Peoples R China"
            },
            {
                "name": "Shengfu Wang",
                "org": "Hubei Univ, Coll Chem & Chem Engn, Wuhan 430062, Hubei, Peoples R China"
            },
            {
                "name": "Kai-Bin Li",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Siqi Zhang",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Taizhou Univ, Dept Chem, Jiaojiang 318000, Peoples R China"
            }
        ],
        "venue": "ANALYST",
        "year": 2017
    },
    "XcHDKL9A": {
        "id": "XcHDKL9A",
        "title": "Side radical influence on the nonlinear optical properties and thermal stability of poled polymer films",
        "abstract": "Films of polyetherketone doped with the chromophores Disperse Red 1 (DR1) and Disperse Red 13 (DR13) were prepared by spin-coating method. By the in situ Second-harmonic Generation (SHG) signal intensity measurement, the optimal poling temperatures were obtained. For the investigated polyetherketone polymer doped with DR1 (DR1/PEK-c) and polyetherketone polymer doped with DR13 (DR13/PEK-c) films, the optimal poling temperatures were 150°C and 140°C, respectively. Under the optimal poling conditions, the high second-order nonlinear optical coefficient ?33(2) = 11.02 pm/V has been obtained for the DR1/PEK-c; and for DR13/PEK-c at the same conditions the coefficient is 17.9 pm/V. The SHG signal intensity DR1/PEK-c could maintain more than 80% of its initial value when the temperature was under 100°C, and the SHG signal intensity of the DR13/PEK-c could maintain more than 80% of its initial value when the temperature was under 135°C.",
        "keywords": [
            "Polymer",
            "Thermal Stability",
            "Signal Intensity",
            "Optical Property",
            "Intensity Measurement"
        ],
        "authors": [
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials Shandong University Jinan 250100 People's Republic of China"
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials Shandong University Jinan 250100 People's Republic of China"
            },
            {
                "name": "Zhihui Qin",
                "org": "State Key Laboratory of Crystal Materials Shandong University Jinan 250100 People's Republic of China"
            },
            {
                "name": "Qingtian Gu",
                "org": "State Key Laboratory of Crystal Materials Shandong University Jinan 250100 People's Republic of China"
            },
            {
                "name": "Wei Shi",
                "org": "State Key Laboratory of Crystal Materials Shandong University Jinan 250100 People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Institute of Semiconductors Academia Sinica Beijing 100083 People's Republic of China"
            }
        ],
        "venue": "Journal of Materials Science",
        "year": 2002
    },
    "libYOwlb": {
        "id": "libYOwlb",
        "title": "Risk factors of hypertension in IgA nephropathy]",
        "abstract": "To explore the risk factors of hypertension in patients with IgA nephropathy in South China.The clinical and renal pathological data of 280 primary IgA nephropathy patients diagnosed by biopsy were analyzed to extinguish the risk factors of hypertension.A total of 96 patients were suffered with hypertension (34.3%). A single-variable analysis showed that the age (>or= 40 years), body weight (>or= 60 kg), absence of macrohematuria, duration of disease (>or= 60 months), blood urea nitrogen >or= 8 mmol/L, serum creatinine (>or= 133 micromol/L), hyperuricaemia, degree of 24 h-proteinuria (>or= 1.5 g), segmental glomerular lesions (>or= 25%), globe glomerular sclerosis (>or= 10%), tubular atrophy (>or= 25%), interstitial fibrosis (>or= 25%), interstitial inflammation (>or= 25%) and arteriole hypertrophy (>or= 10%) were all risk factors related to hypertension; multivariate logistic regression analysis showed that serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors.Many factors were related the hypertension in patients with IgA nephropathy, while serum creatinine, age, arteriole hypertrophy, body weight and 24 h-proteinuria were the independent risk factors of hypertension.",
        "keywords": [],
        "authors": [
            {
                "name": "Shen-heng Li",
                "org": "Department of Nephropathy, Guangdong Provincial People's Hospital, Guangzhou 510080, China."
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Wen-jian Wang",
                "org": ""
            },
            {
                "name": "Xin-ling Liang",
                "org": ""
            },
            {
                "name": "Shuang-xin Liu",
                "org": ""
            },
            {
                "name": "Zhi-ming Ye",
                "org": ""
            },
            {
                "name": "Bin Zhang",
                "org": ""
            },
            {
                "name": "Chao-sheng He",
                "org": ""
            },
            {
                "name": "Yun-feng Xia",
                "org": ""
            },
            {
                "name": "Jian-chao Ma",
                "org": ""
            }
        ],
        "venue": "Zhonghua nei ke za zhi",
        "year": 2008
    },
    "0VMYZYZF": {
        "id": "0VMYZYZF",
        "title": "Thinking and Suggestion on the Teaching of the New Edition \"Elementary Geology\"",
        "abstract": "The new edition\"Elementary Geology\"compared with the old One,we find that there are some obvious variations between them,including the sides of the teaching material such as structure,content,development tendency and penetration with other correlation subjects.So hew to grasp the key,how to make the students understand the structure and knowledge of the new edition\"Elementary Geology\"according to the teaching program which there are more hlgh-level and up-tu-date standards of it.It is necessary that we must probe into the new One,and suggest some rational and feasible proposes for the teaching practice in the days to come.",
        "keywords": [
            "teaching",
            "the new edition\"Elementary Geology\"",
            "thinking and suggestion"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Departmen of Geography,Jiangsu Institute of Education,Nanjing ,China;Department of Urban & Resource Sciences,Nanjing University,Nanjing ,China"
            },
            {
                "name": "ZHANG Jing",
                "org": "Nanhu No.2 Middle School in Nanjing City,Nanjing,,China"
            }
        ],
        "venue": "Journal of Jiangsu Institute of Education(Natural Sciences)",
        "year": 2007
    },
    "1V267AL4": {
        "id": "1V267AL4",
        "title": "DEM DRAINAGE ANALYSIS OF THE SHANXI-SHAANXI GORGE IN THE MIDDLE REACHES OF THE HUANGHE RIVER AND ITS NEOTECTONIC IMPLICATIONS",
        "abstract": "The S-N oriented Shanxi-Shaanxi Gorge crosses the east margin of the Ordos Plateau where the river systems and sub-basins are characterized by an asymmetric E-W-oriented form.Based on Digital Elevation Model(DEM),combing with field observation,this paper analyzed some typical parameters of the drainage development,such as the area,the shape index,the maximum channel length,the maximum channel drop,the network density,and the channel ramification ratio of the Shanxi-Shaanxi Gorge.The result shows that river systems and sub-basins developed in the Shanxi-Shaanxi Gorge is marked by an asymmetric E-W-oriented form.For example,the sub-basins(area>5000km2)are all developed in the west flank of the gorge,and the average area size of sub-basins in the west flank is 1314.55km2,far bigger than in the east.Similarly,compared with that in the west flank,shape index of sub-basins in the west flank is usually much greater.In addition,maximum channel length in the west flank is 200km,much longer than in the east.Likewise,network density of sub-basins in the west flank is at least 10.Contrarily,maximum channel drop in the east flank is 100m at least,markedly bigger than in the west.In the same way,channel ramification ratio of subbasins in the west flank is much bigger than in the east.The differences of river system developed in the Shanxi-shaanxi Gorge may imply that river systems and sub-basins in the west of the Ordos Plateau might have more developed than those in the east which is likely caused by neotectonic differences.Causing analysis indicates that because of the existence of several episodes of different uplifts in the flanks of the Ordos Plateau during the Late Cenozoic,Lüliang Mountains uplift more rapidly than the Ordos Plateau and the Sanmen Lake disappeared,resulting in the strong incising of rivers here and the asymmetrical E-W-oriented development of sub-basins.The formation of the Shanxi-Shaanxi Gorge might have been related mainly to episodic fast eastward tectonic extrusion of the Qinghai-Tibetan Plateau and to the differential vertical uplift in the east margin of the Ordos Plateau during the Late Cenozoic.Features of tectonic morphology of the Shanxi-Shaanxi Gorge can be used to reveal the development history of the Huanghe Rvier.They can also provide quantified geological information for the study of uplift of the east margin of the Ordos Plateau since Late Cenozoic.",
        "keywords": [
            "Huanghe River",
            "Digital Elevation Model",
            "neotectonic",
            "Ordos Plateau",
            "the Shanxi-Shaanxi Gorge"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing "
            }
        ],
        "venue": "Quaternary Sciences",
        "year": 2008
    },
    "aQ5GCYgt": {
        "id": "aQ5GCYgt",
        "title": "Research on APF DC Side Voltage Control Based on TS Type Fuzzy Neural Network Controller",
        "abstract": "Focusing on DC capacitor voltage control problems for the three-phase shunt APF,considering that it is easy to combine TS type fuzzy inference with PID control method,this paper presented a fuzzy neural network controller based on TS fuzzy reasoning(TS-FNNC) and used it for the APF DC side voltage control.The APF instruction current operational structure was identified based on TS-FFNC.The corresponding control strategy was researched.The TS-FNNC connection weights and second layer node membership functions were adjusted by least squares and BP algorithm respectively,so it had fast response speed.The simulation and experimental results verified the effectiveness of the control strategy.",
        "keywords": [
            "fuzzy neural network controller(FNNC)",
            "TS type fuzzy inference",
            "DC side voltage control",
            "active power filter(APF)"
        ],
        "authors": [
            {
                "name": "HUANG Chuanjin",
                "org": "Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "CAO Wensi",
                "org": "North China University of Water Resources and Electric Power,Zhengzhou ,China"
            },
            {
                "name": "GONG Luhong",
                "org": "Zhengzhou Xianghe Group Electric Equipment Co.,Ltd.,Zhengzhou ,China"
            }
        ],
        "venue": "Low Voltage Apparatus",
        "year": 2013
    },
    "7jH0yANS": {
        "id": "7jH0yANS",
        "title": "Intra-genomic variability and pseudogenes in ribosomal ITS regions of Paraplagusia blochii (Pleuronectiformes: Cynoglossidae)",
        "abstract": "Eukaryotic nuclear ribosomal DNA (rDNA) typically evolves in a concerted manner. in which hundreds of rDNA sequences within species show little or no variations, whereas the sequences of different species diverge. There are few studies of the internal transcribed spacer regions (ITS1-5.8S-ITS2) in teleostean fishes and only one report on flatfishes. Here, we reported the discovery of two types of highly divergent ITS1-5.8S-ITS2 rDNA sequences (Type A and B) in the genome of the Bloch's tonguesole. Paraplagusia blochii. These sequences mainly differ in sequence length, secondary structure, and minimum free energy. According to the potential features of pseudogenes. Type B sequences are speculated to be putative pseudogenic ITS regions. Cluster analyses also supported two major clades that corresponded to the sequence type. To the best of our knowledge, this is the first report of the ITS regions of tonguefish, and may therefore provide useful information for future studies of the rDNA of flatfishes as well as the patterns of rDNA evolution in teleostean fishes.",
        "keywords": [
            "Bloch's tonguesole",
            "flatfish",
            "non-concerted evolution",
            "ribosomal RNA",
            "secondary structure"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": "Zhejiang Ocean Univ, Natl Engn Lab Marine Germplasm Resources Explorat, Zhoushan 316022, Peoples R China"
            },
            {
                "name": "Xiaoyu Kong",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510000, Peoples R China"
            },
            {
                "name": "Hairong Luo",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510000, Peoples R China"
            },
            {
                "name": "Shixi Chen",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510000, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510000, Peoples R China"
            },
            {
                "name": "Min Yang",
                "org": "Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, Guangzhou 510000, Peoples R China"
            }
        ],
        "venue": "ANIMAL BIOLOGY",
        "year": 2019
    },
    "6pEoN2vV": {
        "id": "6pEoN2vV",
        "title": "Model Parameters Analysis of Lithium Iron Phosphate Battery for Electric Vehicle",
        "abstract": "In view of that the fitting accuracy of battery model parameters obtained by traditional parameter identification method is relatively poor because the characteristics of lithium iron phosphate(LiFePO4) battery for pure electric vehicle significantly differ at different states of charge,the parameters of equivalent circuit model are analyzed by using electrochemical impedance spectroscopy to study the voltage and dynamic power characteristics of battery in this paper.By comprehensively analyzing the main features of practical charge and discharge conditions,the typical parameter identification working modes of battery are extracted and the model parameters are analyzed with particle swarm optimization algorithm.The validation at different temperatures and usage intervals show that the accuracy of the scheme is rather high.This provides a basis for further investigation into lithium iron phosphate battery.",
        "keywords": [
            "particle swarm optimization",
            "equivalent circuit model",
            "parameter identification",
            "lithium iron phosphate battery"
        ],
        "authors": [
            {
                "name": "Niu Liyong",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Shi Wei",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Jiang Jiuchun",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Zhang Yanru",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Jiang Jun",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "Cao Xueming",
                "org": " School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            }
        ],
        "venue": "Automotive Engineering",
        "year": 2013
    },
    "nILuqND4": {
        "id": "nILuqND4",
        "title": "Design of Embedded Wireless Temperature Control System for Agricultural Greenhouse",
        "abstract": "In order to dynamically real-time monitor the agricultural greenhouse temperature effectively, it proposed to designing a greenhouse temperature control system based on Zigbee wireless network and Linux embedded operating system. The system designed with C/S structure, was composed of lower computer and upper computer in two parts. The lower computer system including temperature acquisition nodes and aggregation nodes: the temperature acquisition nodes complete function of temperature information collection and wireless data transmission in different locations inside the greenhouse, aggregation nodes in addition to completing the data gathering tasks can turn on the fans or heating systems according to feedback control commands from upper computer. The server-side upper computer system stores and analyzes data, and real-time controls lower computer system according to its analysis results. It had proved in practice that the system can accurately monitor the greenhouse temperature, effectively reduced wiring costs and it is helpful to reduce labor costs and increase crop yields.",
        "keywords": [
            "agricultural greenhouses",
            "lower computer",
            "upper computer",
            "temperature monitoring"
        ],
        "authors": [
            {
                "name": "Li Lili",
                "org": "School of Electronic and Information Engineering, Liaoning Technical University, Fuxin Liaoning "
            },
            {
                "name": "Shi Wei",
                "org": "School of Electronic and Information Engineering, Liaoning Technical University, Fuxin Liaoning "
            }
        ],
        "venue": "Chinese Agricultural Science Bulletin",
        "year": 2011
    },
    "1JFepQNB": {
        "id": "1JFepQNB",
        "title": "Forecasting the Effect of Water Infusion for Coal Seam Based on BP Neural Network",
        "abstract": "The scientific forecasting of water infusion for coal seam effect is the important basis adjusting water infusion technological parameter.Water infusion for coal seam effect is affected by many factors,and it is a very complicated non-linear problem,so it is very difficult to be solved by traditional mathematical methods.Specifically for the geology factor and water infusion technological parameter affecting the coal seam water infusion effect,the neural network with the non-linear mapping function is adopt to forecast coal seam water infusion effect,whose error is 6.25%.With comparison and the examples,the method using in this paper has higher accuracy than others,and can be used for guiding the actual water infusion for coal seam engineering.",
        "keywords": [
            "Influencing factor",
            "Coal seam water infusion effect",
            "Forecasting",
            "Neural network"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin Liaoning ,China"
            },
            {
                "name": "LIU Jian-hui",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin Liaoning ,China"
            },
            {
                "name": "QIN Shu-yu",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin Liaoning ,China"
            }
        ],
        "venue": "Computer Simulation",
        "year": 2009
    },
    "YqJlNfog": {
        "id": "YqJlNfog",
        "title": "The complete mitochondrial genome sequence of Asterorhombus intermedius (Pleuronectiformes: Bothidae)",
        "abstract": "AbstractThe complete mitogenome of Asterorhombus intermedius is 16,886 bp in length, containing 37 genes, among them, ND6 and eight tRNA genes are encoded by L-strand, and other genes by H-strand, which are the same as those of typical mitogenome in fishes. A striking finding is a novel genomic-scale gene rearrangement related nine genes, including ND6 and six tRNA encoded by the L-strand grouped to a cluster of Gln-Ala-Cys-Tyr-Ser1-ND6-Glu. Also, the genes of this cluster with identical transcriptional polarities maintained the original gene order. In addition, the order of 12S-Val-16S-Leu1 fragment rearranged to 12S-16S-Val-Leu1, and that of Ser1-Asp-COII fragment rearranged to Ser1-Asp-ND6.",
        "keywords": "",
        "authors": [
            {
                "name": "Shixi Chen",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Hairong Luo",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            },
            {
                "name": "Xiaoyu Kong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China;"
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2019
    },
    "lIOKU1H7": {
        "id": "lIOKU1H7",
        "title": "An IDH1 mutation inhibits growth of glioma cells via GSH depletion and ROS generation.",
        "abstract": "The isocitrate dehydrogenase 1 (IDH1) gene mutation occurs frequently in glioma. While some studies have demonstrated that IDH1 mutations are associated with prolonged survival, the mechanism remains unclear. In this study, we found that growth was significantly inhibited in glioma cells overexpressing the mutated IDH1 gene. Furthermore, these cells were characterized by decreased intracellular NADPH levels accompanied by glutathione (GSH) depletion and reactive oxygen species (ROS) generation. Moreover, the increased apoptosis and the decreased proliferation were found in the glioma cells overexpressing the mutant IDH1 gene. Accordingly, our study demonstrates that using H2O2-regulated mutant IDH1 glioma cells could obviously increase the inhibition of cell growth; nevertheless, GSH had the opposite result. Our study provides direct evidence that mutation of IDH1 profoundly inhibits the growth of glioma cells, and we speculate that this is the major factor behind its association with prolonged survival in glioma. Finally, our study indicates that depletion of GSH and generation of ROS are the primary cellular events associated with this mutation.",
        "keywords": [
            "Glioma",
            " IDH1",
            " ROS",
            " GSH"
        ],
        "authors": [
            {
                "name": "Jinlong Shi",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001, Jiangsu, People's Republic of China."
            },
            {
                "name": "Hao Zuo",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Lanchun Ni",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Liang Xia",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Longxiang Zhao",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Mingjie Gong",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Dekang Nie",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Peipei Gong",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Daming Cui",
                "org": "Department of Neurosurgery, Shanghai Tenth People’s Hospital,Tongji University School of Medicine,Shanghai,People’s Republic of China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            }
        ],
        "venue": "Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology",
        "year": 2014
    },
    "0ubPwOqK": {
        "id": "0ubPwOqK",
        "title": "Clinical observation of different blood purification treatments on uremic encephalopathy",
        "abstract": "Objective:To observe the different effects of CBP,HDF and HD on UE.Methods: 46 patients with UE were divided into CBP group(n=15),HD group(n=16) and HDFgroup(n=15) randomly.The therapeutic efficacy,remission rate,electrolytes,serum Bun,serum Cr and MAP were observed in the process of treatment.Results: The remission rates within a week were 100%(CBP group),86.7%(HDF group)and 62.5%(HD group) respectivey(P<0.05);CBP could most remove BUN,Scr and correct turbulenice of electrolyte and acid-alkali(P<0.05);The change of MAP was insignificationly in CBP,the hypotision occurred 4 times(4/75)in HDF group and 11 times(11/80) in HD group respectively.Conclusion: CBP could most remove BUN,Scr and correct turbulence of electrolyteand acid-alkali,The side effect is very small to cardiovascular system with CBP therapy.The paients can tolerance mostly.",
        "keywords": [
            "renaldalysis",
            "brain diseases",
            "decontamination",
            "uremia",
            "blood",
            "hemodiafiltration"
        ],
        "authors": [
            {
                "name": "XIANG Qing",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical Universitiy,Nanning ,China"
            },
            {
                "name": "YIN You-sheng",
                "org": "Department of Nephrology,Affiliated Hospital of GuiLin Medical College,Guilin ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical Universitiy,Nanning ,China"
            },
            {
                "name": "WU Jin-yu",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical Universitiy,Nanning ,China"
            },
            {
                "name": "XIANG Cai-chun",
                "org": "Department of Nephrology,First Affiliated Hospital,Guangxi Traditional Chinese Medical Universitiy,Nanning ,China"
            }
        ],
        "venue": "Academic Journal of PLA Postgraduate Medical School",
        "year": 2008
    },
    "rzQL3hWQ": {
        "id": "rzQL3hWQ",
        "title": "Effect of Tianqi Injection in Patients with Chronic Renal Failure",
        "abstract": "Objective:To investigate the effect of Tianqi Injection in patients with chronic renal failure(CRF). Methods:52 patients with CRF were randomized into the treating group(n=28) and the control group(n=24). Base on the routine therapy, Tianqi Injection was used to the treating group additionally, and Amino Acid Injection was used to the control group, 4 weeks constituted one treatment course. The changes of blood-lipid and renal function were observed before and after treatment. Results:The total effective rate was 85.71% in treating group and 58.33% in control group (P<0.01). After treatment, the serum levels of total cholesterol(TC),triglycerides (TG) ,and low density lipoprotein (LDL) were decreased in treating group (P<0.01 or P<0.05), and the effect was better than that in the control group(P<0.01). TG and high density lipoprotein (HDL) in control group after treatment did not differ from those before treatment. The levels of BUN and Scr were significantly decreased in 2 groups after treatment, and the effect of treating group was better than that in the control group(P<0.01 or P<0.05). Conclusion:Tianqi Injection could delay CRF progression by improving the blood-lipid and renal function of patients with CRF. It was worth applying to clinical therapy further.",
        "keywords": [
            "traditional Chinese medicine therapy",
            "Tianqi Injection",
            "chronic renal failure"
        ],
        "authors": [
            {
                "name": "WU Jin-yu",
                "org": " Department of Nephrology, The First Affiliated Hospital of Guangxi College of TCM, Nanning ,Guangxi,China"
            },
            {
                "name": "HUANG Xue-xia",
                "org": " Department of Nephrology, The First Affiliated Hospital of Guangxi College of TCM, Nanning ,Guangxi,China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Nephrology, The First Affiliated Hospital of Guangxi College of TCM, Nanning ,Guangxi,China"
            }
        ],
        "venue": "Liaoning Journal of Traditional Chinese Medicine",
        "year": 2005
    },
    "qUx5B9H9": {
        "id": "qUx5B9H9",
        "title": "Study of carrier lifetime of silicon by OPTP method",
        "abstract": "",
        "keywords": [
            "refractive index",
            "spectroscopy",
            "absorption",
            "silicon"
        ],
        "authors": [
            {
                "name": "lei hou",
                "org": ""
            },
            {
                "name": "xianjin shao",
                "org": ""
            },
            {
                "name": "lei yang",
                "org": ""
            },
            {
                "name": "zhiquan wang",
                "org": ""
            },
            {
                "name": "like zhang",
                "org": ""
            },
            {
                "name": "mengmeng zhao",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2015
    },
    "pfzA4PAN": {
        "id": "pfzA4PAN",
        "title": "The sedimentary characteristics in the Late Pleistocene in Southern Ningxia and its tectonic significance",
        "abstract": "The studies of the Quaternary sediments,the sedimentation in southern Ningxia and the Quaternary chronologic dating show many late Pleistocene sedimentary basins occurred in southern Ningxia in the late Pleistocene.The Late Pleistocene sediments in the basins are mainly featured by alluvial fan sediments,lacustrine argillaceous-silty sediments,basin-margin-slope lithofacies associations,first-terrace sediments of modern fluvial and loess sediment.The sedimentation of these basins suggests that the late Pleistocene sedimentary basin was controlled by regionally tectonic extension,which indicates that an obvious tectonic extension affected the southern Ningxia in the northeastward growth and uplift of the Tibetan Plateau,and provides a sedimentological evidence for the phasal uplift of the Tibetan Plateau.",
        "keywords": [
            "Late Pleistocene",
            "Northeastern margin of the Tibetan Plateau",
            "Sedimentary basin",
            "Southern Ningxia",
            "Tectonic extension"
        ],
        "authors": [
            {
                "name": "XU Tao",
                "org": "College of Earth Science and Resources,Chang'an University,Xi'an ,China"
            },
            {
                "name": "YANG Jiaxi",
                "org": "College of Earth Science and Resources,Chang'an University,Xi'an ,China"
            },
            {
                "name": "LIU Yuan",
                "org": "College of Earth Science and Resources,Chang'an University,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "WEI Wei",
                "org": "Balikun Tonghe Mining Co.Ltd.,Hami ,China"
            }
        ],
        "venue": "Earth Science Frontiers",
        "year": 2013
    },
    "E29fPOgT": {
        "id": "E29fPOgT",
        "title": "Building and validation of a prognostic model for predicting extracorporeal circuit clotting in patients with continuous renal replacement therapy.",
        "abstract": "To develop a predictive model for circuit clotting in patients with continuous renal replacement therapy (CRRT).A total of 425 cases were selected. 302 cases were used to develop a predictive model of extracorporeal circuit life span during CRRT without citrate anticoagulation in 24 h, and 123 cases were used to validate the model. The prediction formula was developed using multivariate Cox proportional-hazards regression analysis, from which a risk score was assigned.The mean survival time of the circuit was 15.0 ± 1.3 h, and the rate of circuit clotting was 66.6 % during 24 h of CRRT. Five significant variables were assigned a predicting score according to the regression coefficient: insufficient blood flow, no anticoagulation, hematocrit ≥0.37, lactic acid of arterial blood gas analysis ≤3 mmol/L and APTT < 44.2 s. The Hosmer-Lemeshow test showed no significant difference between the predicted and actual circuit clotting (R (2) = 0.232; P = 0.301).A risk score that includes the five above-mentioned variables can be used to predict the likelihood of extracorporeal circuit clotting in patients undergoing CRRT.",
        "keywords": [
            "Continuous renal replacement therapy",
            " Empirical formula",
            " Predictive model",
            " Circuit clotting",
            " Circuit life span"
        ],
        "authors": [
            {
                "name": "Xia Fu",
                "org": "Southern Medical University, Guangzhou, 510080, China, fx-rena@163.com."
            },
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Li Song",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Huigen Huang",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Jing Wang",
                "org": "Nursing Systems Department,University of Texas Health Science Center at Houston School of Nursing,Houston,USA"
            },
            {
                "name": "Yuanhan Chen",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Li Zhang",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Zilin Quan",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology,Guangdong General Hospital and Guangdong Academy of Medical Sciences,Guangzhou,China"
            }
        ],
        "venue": "International urology and nephrology",
        "year": 2014
    },
    "SHZJpm8R": {
        "id": "SHZJpm8R",
        "title": "Hierarchical porous Co(OH)F/Ni(OH)2: A new hybrid for supercapacitors",
        "abstract": "Abstract   A new hybrid hierarchical porous Co(OH)F/Ni(OH) 2  for supercapacitors was fabricated via one-pot hydrothermal method. X-ray diffraction (XRD) revealed that the Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid was composed of orthorhombic Co(OH)F and hexagonal Ni(OH) 2  phases. X-ray photoelectron spectra (XPS) illustrated the presence of O1s, F1s, Co2p and Ni2p for the Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid. The scanning/transmission electron microscopy (SEM/TEM) showed that the Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid exhibited the morphology of both the nanorods of bare Co(OH)F and nanoflakes of bare Ni(OH) 2 . The energy dispersive spectrometry (EDS) and mapping results showed the Co/Ni ratio of 3.1:1 and uniform distributions of O, F, Co and Ni elements of the Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid. Nitrogen sorption measurements suggest the hierarchical porous structure of the Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid. The Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) hybrid showed the more attractive electrochemical performance than the other Co(OH)F/Ni(OH) 2  candidates (Co/Ni = 1:0, 1:1, 1:3, 0:1) due to the stronger synergistic effect of Co and Ni redox species, exhibiting high specific capacity and rate behavior (104-98 C g −1  at 1–16 A g −1 ) together with excellent cycling stability (116% retention/5000 cycles/6 A g −1 ). Furthermore, the designed activated carbon (AC)//Co(OH)F/Ni(OH) 2  (Co/Ni = 3:1) asymmetric capacitor exported both high energy and power densities (13.8–8 Wh kg −1 /0.53–4.7 kW kg −1 ) along with excellent cycle life (121% retention/10,000 cycles/4 A g −1 ), showing the superior performance than the other AC//Co(OH)F/Ni(OH) 2  capacitors (Co/Ni = 1:0, 1:1, 1:3, 0:1).",
        "keywords": "",
        "authors": [
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Danfeng Ying",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Yongfa Huang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan, 411105, PR China"
            }
        ],
        "venue": "Electrochimica Acta",
        "year": 2018
    },
    "ssaJiY1r": {
        "id": "ssaJiY1r",
        "title": "The Multi-time Scale Analysis on Climate Change and Runoff Processes in the Tianshan Mountains,Xinjiang",
        "abstract": "Based on the temperature,precipitation and annual runoff data of the Tianshan Mountains,the paper studied the changing trend and multi-time scale correlation between the annual runoff and climatic factors by using methods of wavelet transform and nonparametric test.The results show that: 1) the increasing trends of the annual runoff,temperature and precipitation are significant in the Manas River Basin and Tarim River Basin;2) the primary periods of the temperature are respectively 11,18 and 22 years,that of precipitation are 10,20 and 22 years on decadal time scale in the headstream areas of the Tarim River Basin;in addition,the temperature of the Manas River Basin holds the periods of 10 and 22 years and the precipitation represents the periodic variation of 20 and 22 years;meanwhile,both temperature and precipitation show the inter-annual periodic variation of 3-6 years in the headstream areas of the Manas River and Tarim River;3) the abrupt change points of annual runoff,temperature and precipitation occurred respectively in 1993,1993 and 1992,however,that of the Manas River are significant in 1995,1988 and 1996;and 4) the multi time scale correlativity is significant between the annual runoff and climatic factors in the headstream areas of the two basins.",
        "keywords": [
            "climatology",
            "cross-wavelet",
            "multi scale correlation",
            "climate change"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China"
            },
            {
                "name": "ZHANG Qing-qing",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography,CAS,Urumqi ,China;Graduate University of Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Natural Resources",
        "year": 2011
    },
    "K3YzZRUC": {
        "id": "K3YzZRUC",
        "title": "Applied anatomy of A1 segment of anterior cerebral artery",
        "abstract": "Objective:To study the A1 segment of anteriorg cerebral artery(ACA) via pterional approach under the operative microscope,we expect to provide useful anatomic data for the surgical operation in this area.Method:10 adult cadaveric heads in which the arteries were injected with the colored emulsion were dissected,exposing the A1 segments of anterior cerebral artery via pterional approach under the operative microscope step by step.Making an observation and measuring its structures,perforating branch and adjacent vessel.Result:A1 segment of ACA was found in each cerebral hemisphere.The difference of bilateral A1 segment diameter and length was not significant in the same cadaver heads.Many anatomical variations related to shapes、perforating artery and adjacency were found in A1 segment of ACA.A lot of perforating branches arose from the inferior wall within 3mm distance near the original of all A1 segments Most Heubner's recurrent arteries coursed companying with the distal A1 segments.Conclusion:The variations of A1 segments of anterior cerebral artery are not only related to the formation of anterior communicating artery aneurysms but also provide the difficulty to clip the aneurysms.A1 segment send out a lot of important perforating branches which should be discerned and protected carefully during operation.Well understanding of the microanatomy of A1 segments can provide guidance to the operation,protect the important vessel and nerves,reduce the serious operative complications.",
        "keywords": [
            "A1 segment of anterior cerebral artery",
            "Pterional approach",
            "Anatomy"
        ],
        "authors": [
            {
                "name": "XU Hui",
                "org": "Department of Neurosurgery,Nantong Hospital of traditional Chinese Medicine,Nantong "
            },
            {
                "name": "GU Zhikai",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University"
            }
        ],
        "venue": "Journal of Nantong University(Medical Sciences)",
        "year": 2010
    },
    "xCVe5H7f": {
        "id": "xCVe5H7f",
        "title": "Cultural Roots on University Internal Quality Assurance System",
        "abstract": "University internal quality assurance system has its cultural roots,and scientific and rational internal quality assurance system needs strong cultural roots.Academic cultural is the essential characteristics of the university culture based on its organization characteristics.University quality culture is a cultural system contains academic cultural as the premise,human culture as the key,science culture as the core and public culture as the supplement.University needs reshape quality culture system through designing the system culture,interpreting cultural orientation,revealing the culture,encouraging cultural behavior and so on,to strengthen the cultural roots of university internal quality assurance system.",
        "keywords": [
            "academic culture",
            "culture system",
            "internal quality assurance"
        ],
        "authors": [
            {
                "name": "Liu Xuezhong",
                "org": "Persident's Office,Fuyang Normal College,Fuyang "
            },
            {
                "name": "Shi Wei",
                "org": "Persident's Office,Fuyang Normal College,Fuyang "
            }
        ],
        "venue": "China Higher Education Research",
        "year": 2012
    },
    "tFELJ1Db": {
        "id": "tFELJ1Db",
        "title": "Occurrence of perfluoroalkyl acids including perfluorooctane sulfonate isomers in Huai River Basin and Taihu Lake in Jiangsu Province, China.",
        "abstract": "The spatial distribution of 10 perfluoroalkyl acids including linear and branched (six monotrifluoromethyl isomers) perfluorooctane sulfonate (PFOS) in surface water was investigated in Huai River Basin and Taihu Lake in Jiangsu Province, China. In the water samples from Huai River Basin, perfluorooctanoic acid (PFOA) and PFOS were the predominant compounds (mean 18 ng/L and 4.7 ng/L, respectively), while in samples from Taihu Lake, PFOA, perfluorohexanoic acid (PFHxA), and PFOS were the predominant compounds (mean 56 ng/L, 19 ng/L, and 15 ng/L, respectively). Branched PFOS (Br-PFOS) isomers accounting for 48.1% to 62.5% of total PFOS were enriched in all samples from Taihu Lake, compared to technical electrochemical fluorination (ECF) PFOS (Br-PFOS ∼30.0%), while the similar phenomena were not found in samples from Huai River Basin (Br-PFOS 29.0-35.0%). Principal component analysis (PCA) on the percentages of the individual isomer showed that the first two components accounted for 78.4% and 15.3% of the overall observed data variance. Samples from Huai River Basin were grouped together with the ECF PFOS standard suggesting the profiles were similar, while samples from Taihu Lake were grouped by themselves, suggesting that isomer profiles in these samples were different from that of Huai River Basin. The obvious difference in isomer profiles probably results from the different environmental behaviors of PFOS isomers and/or unknown sources (PFOS or PFOS precursors).",
        "keywords": [],
        "authors": [
            {
                "name": "Nanyang Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Beibei Zhang",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Guanyong Su",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jianfang Feng",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiaowei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2013
    },
    "YMYrQzFz": {
        "id": "YMYrQzFz",
        "title": "Signal bandwidth of general n/spl times/n multimode interference couplers",
        "abstract": "",
        "keywords": [
            "wavelength division multiplexing",
            "light interference"
        ],
        "authors": [
            {
                "name": "hongzhen wei",
                "org": ""
            },
            {
                "name": "jinzhong yu",
                "org": ""
            },
            {
                "name": "zhongli liu",
                "org": ""
            },
            {
                "name": "xiaofeng zhang",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "changshui fang",
                "org": ""
            }
        ],
        "venue": "Journal of Lightwave Technology",
        "year": 2001
    },
    "yhV1GH9M": {
        "id": "yhV1GH9M",
        "title": "Fabrication of 2 × 2 tapered multimode interference coupler",
        "abstract": "The authors demonstrate a 3 dB 2/spl times/2 parabolically tapered multimode interference (MMI) coupler with a large cross-section and space between the different ports using silicon-on-insulator technology. The device exhibits a uniformity of <0.8 dB and can be used in the realisation of an MMI-based optical switch with a high extinction ratio.",
        "keywords": [
            "optical couplers"
        ],
        "authors": [
            {
                "name": "Hongzhen Wei",
                "org": "Inst. of Semicond., Acad. Sinica, Beijing, China"
            },
            {
                "name": "Jinzhong Yu",
                "org": ""
            },
            {
                "name": "Zhongli Liu",
                "org": ""
            },
            {
                "name": "Xioafeng Zhang",
                "org": ""
            },
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": ""
            }
        ],
        "venue": "Electronics Letters",
        "year": 2000
    },
    "isCowbaY": {
        "id": "isCowbaY",
        "title": "Bragg reflectors and 2D photonic crystals in the THz region",
        "abstract": "",
        "keywords": [
            "photonic crystal",
            "reflection",
            "deep reactive ion etching",
            "lasers",
            "photonic crystals",
            "terahertz radiation"
        ],
        "authors": [
            {
                "name": "hongqian sun",
                "org": "lehigh university"
            },
            {
                "name": "wei shi",
                "org": "lehigh university"
            },
            {
                "name": "zhan fu",
                "org": "lehigh university"
            },
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            },
            {
                "name": "yuliya b zotova",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2005
    },
    "PcgjHrvc": {
        "id": "PcgjHrvc",
        "title": "Analysis of on-site partial-discharge test on 750 kV transformers",
        "abstract": "This paper analyzes the problems concerning procedure, standards, and process in the on-site acceptance partial-discharge (PD) test on the 750 kV transformers. Some suggestions are therefore offered as follows: (1) increase the power frequency withstand test voltage for 750 kV transformers; (2) avoid to perform PD test repeatedly; (3) take practical measures if PD quantity exceeds the criterion stated in standard; (4) redefine the PD inception voltage and extinction voltage; (5) use reliable on-line monitoring apparatus when necessary. These suggestions can also serve as a reference for the same test on 1000 kV transformer.",
        "keywords": [
            "Partial discharge",
            "Test",
            "Transformer"
        ],
        "authors": [
            {
                "name": "LI Yun-ge",
                "org": "Northwest Grid Company(Northwest Grid Company),Lanzhou,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an Jiaotong University(Xi'an Jiaotong University,Xi'an Jiaotong Univ,Xi'an Jiaotong Univ.),Xi An,China"
            },
            {
                "name": "ZHANG Xiang-quan",
                "org": "Northwest Grid Company(Northwest Grid Company),Lanzhou,China"
            },
            {
                "name": "Shao Zhou Han",
                "org": "Northwest Grid Company(Northwest Grid Company),Lanzhou,China"
            },
            {
                "name": "Xuan Wang",
                "org": "China Electric Power Research Institute(China Electric Power Research Institute,Electric Power Research Inst),Beijing,China"
            },
            {
                "name": "Rong Xing Wan",
                "org": "Northwest Grid Company(Northwest Grid Company),Lanzhou,China"
            },
            {
                "name": "SONG Zhao-hui",
                "org": "Northwest Grid Company(Northwest Grid Company),Lanzhou,China"
            }
        ],
        "venue": "Gaoya Dianqi/High Voltage Apparatus",
        "year": 2007
    },
    "IJO6WmSD": {
        "id": "IJO6WmSD",
        "title": "Mesozoic deformation of Dabashan curvilinear structural belt of Qinling orogen",
        "abstract": "The Dabashan structural belt is a part of south Qinling Mountains,which has been regarded as a foreland thrusting belt of the collisional belt of the north and south China plates.The results of the researches show that the curvilinear structural belt,to the south of Chengkou-Fangxian thrust fault in the Dabashan mountains,has undergone strong superimposed deformation during the Mesozoic.The Dabashan curvilinear structural belt is composed of linear folds with curvilinear fold hinges and some curvilinear thrust faults(D2),which was formed during the major phase of deformation of south Dabashan.In the western curvilinear structural belt,the folds of D2 with fold axes of nearly south to north trending superimposed on the early wide folds with axis of nearly west to east(D1),and formed a typical cross superimposed structure.In the central and eastern parts,fold axes of D2 were gradually turned to nearly east-west.The geological mapping shows that there existed a phase of deformation that the fold axes were of north to nearly south to north direction before the formation of the curvilinear structural belt.Based on the deformational sequence,deformed strata,and regional geology,the authors believe that the time of D1,both in western and in central and eastern Dabashan curvilinear structural belt,is the late Triassic to the early Jurassic.It is possible that the deformation D1 was related to the collision between north China block and Yangtze block.On the other hand,the geological relationship,geochronology and AFT data show that the main deformation time of D2,is about the late Jurassic to the early Cretaceous(160-110 Ma).So the Dabashan curvilinear structural belt recorded two phases of deformation which were formed during different tectonic settings.It is of great significance for the understanding of the evolution of Qinling orogen.",
        "keywords": [
            "Mesozoic deformation",
            "Qinling orogen",
            "Dabashan curvilinear structural belt",
            "detachment deformation"
        ],
        "authors": [
            {
                "name": "Hu Jianmin",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "Shi Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "Qu Hongjie",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "Chen Hong",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            },
            {
                "name": "Wu Guoli",
                "org": "Institute of Geology and Geophysics,Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "Tian Mi",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijing ,China"
            }
        ],
        "venue": "Earth Science Frontiers",
        "year": 2009
    },
    "Z5ZbX3sK": {
        "id": "Z5ZbX3sK",
        "title": "Effects of pulse high-volume hemofiltration on serum concentration of moxifloxacin in patients with continuous renal replacement therapy",
        "abstract": "AIM: To study the changes of the serum moxifloxacin concentration in the patients with continuous renal replacement therapy when applied for pulse high-volume hemofiltration(PHVHF).METHODS: The patients applied for PHVHF were intravenously given moxifloxacin at the dose of 400 mg in 60 min.Blood samples were collected from the arterial(input) and venous(output) lines of the extracorporeal circuit immediately at different time points after the beginning of infusion,and replacement fluid was taken at the corresponding time points.The serum concentration of moxifloxacin was measured by high-performance liquid chromatography(HPLC).The pharmacokinetics parameters were determined using DAS 2.1.1 software.RESULTS: Two-compartment model was used to achieve the best concentration-time relation of moxifloxacin.The levels of blood urea nitrogen(BUN),serum creatinine(SCr) and serum K+ were obviously decreased after application of PHVHF(P<0.05).The peak serum concentration(Cmax) of moxifloxacin was(4.843±1.854) mg/L.The half-life(T1/2) was(4.822±2.126) h and the peak time(Tmax) was(1.31±0.59) h.The total volume of distribution(Vd) was(82.63±24.69) L.The total clearance(CLtot) was(14.36±8.43) L/h.All the ratios of area under the concentration-time curve(AUC) to 90% minimal inhibitory concentration(MIC90) were more than 100 when the values of MIC90 were 0.25 mg/L,0.12 mg/L and 0.03 mg/L.All the values of Cmax/MIC90 were more than 10 when the values of MIC90 were 0.25 mg/L,0.12 mg/L and 0.03 mg/L.CONCLUSION: Application of PHVHF obviously improves the renal functions and eliminates a part of moxifloxacin in the serum.However,the serum concentration of moxifloxacin remains at the effective level for controlling the pathogenic bacteria.",
        "keywords": [
            "Moxifloxacin",
            "Pulse high-volume hemofiltration",
            "Renal replacement therapy"
        ],
        "authors": [
            {
                "name": "LI Li",
                "org": "Graduate School,Southern Medical University,Guangzhou ,China;Department of Critical Care Medicine,Yuebei People's Hospital,Shaoguan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "CHEN Tie-feng",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": "Department of Nephrology,Guangdong General Hospital,Guangzhou ,China"
            }
        ],
        "venue": "Chinese Journal of Pathophysiology",
        "year": 2011
    },
    "2iwzINrP": {
        "id": "2iwzINrP",
        "title": "Tandem Duplication and Random Loss for mitogenome rearrangement in Symphurus (Teleost: Pleuronectiformes).",
        "abstract": "The mitochondrial genomes (mitogenomes) of flatfishes (Pleuronectiformes) exhibit highly diversified types of large-scale gene rearrangements. We have reported that the mitogenomes of Crossorhombus azureus (Bothidae), Samariscus latus (Samaridae) and Cynoglossus fishes (Cynoglossidae) show different types of gene rearrangements.In the present study, the complete mitogenomes of two Symphurus species (Cynoglossidae), Symphurus plagiusa and Symphurus orientalis, were determined. The gene order in the S. plagiusa mitogenome is the same as that of a typical vertebrate (without any gene rearrangements). Surprisingly, large-scale gene rearrangements have occurred in S. orientalis. In the rearranged fragment from the control region (CR) to the WANCY tRNA cluster (tRNA cluster of tRNA-W, tRNA-A, tRNA-N, tRNA-C and tRNA-Y) in the S. orientalis mitogenome, tRNA-V and tRNA-M have been translocated to the 3' end of the 16S rRNA gene, with six large intergenic spacers over 20 bp in length. In addition, an origin for light-strand replication (OL) structure that is typically located in the WANCY region was absent in both the S. plagiusa and S. orientalis mitogenomes. It is generally recognized that a sequence in the WANCY region that encodes tRNAs forms a hairpin structure (OL-like structure) and can act as the OL when the typical locus is lost. Moreover, an additional OL-like structure was identified near the control region in the S. plagiusa mitogenome.The positions of the intergenic spacers and the rearranged genes of the S. orientalis mitogenome strongly indicate that the mechanism underlying the rearrangement of this mitogenome was Tandem Duplication and Random Loss. Additionally, two OL-like regions substituting for the typical locus were found in the S. plagiusa mitogenome. We speculate that the ancestral mitogenomes of S. plagiusa and S. orientalis also had this characteristic, such that if both OL-like structures functioned during mitochondrial replication, they could initiate duplicate replications of the light strand (L-strand), leading to duplication of the region between the two structures. We consider that this mechanism may account for the gene duplication that occurred during the gene rearrangement process in the evolution of the ancestral mitogenome to the S. orientalis mitogenome.",
        "keywords": [
            "proteomics",
            "microarrays"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, PR China. shiwei@scsio.ac.cn."
            },
            {
                "name": "Li Gong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, PR China. gongli1027@163.com."
            },
            {
                "name": "Shu-Ying Wang",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, PR China. czwangshuying@163.com."
            },
            {
                "name": "Xian-Guang Miao",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, PR China. miaoxianguang2008@163.com."
            },
            {
                "name": "Xiao-Yu Kong",
                "org": "CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou, 510301, PR China. xykong@scsio.ac.cn."
            }
        ],
        "venue": "BMC genomics",
        "year": 2015
    },
    "OOdSQgeC": {
        "id": "OOdSQgeC",
        "title": "Research on Three-phase Four-wire APF Based on Predictive Current Control Trategy",
        "abstract": "Focusing on the problem of reduction of the APF compensating ability caused by the system inherit time delay of the Active Power Filter,a control strategy is givh based on NNPC which is studied deeply in basic principle,designs the NNPC model on which the predictive current control of the three-phase four-wire APF is achieved.The simulation results prove that the NNPC strategy has the benefit of good tracing capacity and eliminates the current glitch on the network side.",
        "keywords": [
            "three-phase four-wire active power filter predictive controller"
        ],
        "authors": [
            {
                "name": "CHEN Liang",
                "org": "Zhongzhou University1,Zhengzhou ,P.R.China"
            },
            {
                "name": "HUANG Chuan-jin",
                "org": "Zhongzhou University1,Zhengzhou ,P.R.China"
            },
            {
                "name": "CAO Wen-si",
                "org": "North China Institute of Water Conservancy and Hydroelectric Power2,Zhengzhou ,P.R.China"
            },
            {
                "name": "SHI Wei",
                "org": "Zhongzhou University1,Zhengzhou ,P.R.China"
            }
        ],
        "venue": "Science Technology and Engineering",
        "year": 2012
    },
    "3Fn0k03g": {
        "id": "3Fn0k03g",
        "title": "Soluble Urokinase Plasminogen Activator Receptor is Associated with Coronary Artery Calcification and Cardiovascular Disease in Patients Undergoing Hemodialysis.",
        "abstract": "suPAR is associated with the CAC score and is a risk factor for new-onset CVD in patients undergoing hemodialysis.",
        "keywords": [
            "Cardiovascular diseases",
            "Hemodialysis",
            "SuPAR",
            "Vascular calcification"
        ],
        "authors": [
            {
                "name": "Wenjuan Wu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Yanhai Cui",
                "org": "Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, China."
            },
            {
                "name": "Juan Hu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Ruyi Liao",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Sijia Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Liyi Mo",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Lixia Xu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Yuanhan Chen",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Zhiwen Lian",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Xiulan Tian",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Zhuo Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Ruizhao Li",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Li Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Huaban Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Jianchao Ma",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Ting Lin",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Zhonglin Feng",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Wei Dong",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Guibao Ke",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Pingjiang Ge",
                "org": "Department of Otolaryngology, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou, China."
            },
            {
                "name": "Zhiming Ye",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Wenjiang Wang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Bing Zhang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Wei Shi",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Xinling Liang",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            },
            {
                "name": "Shuangxin Liu",
                "org": "Department of Nephrology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangdong Geriatrics Institute, Guangzhou, China."
            }
        ],
        "venue": "Kidney & blood pressure research",
        "year": 2018
    },
    "qlPYfaxm": {
        "id": "qlPYfaxm",
        "title": "Base on MSP430 and DL/PT645 Communication Protocol Of Intelligent power-convertor’s Design",
        "abstract": "The technology about the Intelligent apparatus is a recently rising technology,it based on the computer and communication.This paper introduces the related knowledge,developing state.the current achievements in the field are summarized.It analyzes the existing abuse of the electrodynamic meter’s charge nowadays.Intelligent power-convertor’s charge changes the past serving manner of manual work,avoids the disadvantages of the manual work,such as the wrong,liaking,and estimating reading,the great time lag,the low efficiency,the existing hidden safety problems.It not only saves the manpower and material resources,but also enhances the security. This paper’main content is Base on DL/PT645 communication protocol of Intelligent power-convertor’s hardware design process. Users will be at home for the cumulative and surplus electricity quantity.This system’s main content involves the hardware chooses to use with design and the software to use with design.The system in consumption and stability is optinal effect through selection hardware.",
        "keywords": [
            "microcontroller",
            "Intelligent apparatus",
            "Remote meter-reading",
            "Intelligent power-convertor"
        ],
        "authors": [
            {
                "name": "SUN Meijun",
                "org": "College of Information Engineering,Taiyuan University of Technology,Taiyuan "
            },
            {
                "name": "SHI Wei",
                "org": "College of Information Engineering,Taiyuan University of Technology,Taiyuan "
            }
        ],
        "venue": "Software",
        "year": 2012
    },
    "qTj2grNQ": {
        "id": "qTj2grNQ",
        "title": "The Effect of Injected Multimode Vacuum Field Upon Y-Squeezing of Generalized Electric-Field Component of Multimode Functional Superposition State Light-Field",
        "abstract": "The multimode squeezed state theory is used to analyze and research the effect of both squeezed amplitude and squeezed quantity of equal-power 2m-power Y-squeezing of the generalized electric-field component on multimode functional superposition state light-field upon the injected multimode vacuum field in detail.The findings indicate that the injected multimode vacuum light-field can make the generalized electric-fielcl component of 3MFSS(3 states superposed multimode functional superposition state)light-field appear the Y-sqneezing eggect of 2m-power under the certain condition,can cause the squeezed effect of the quantum light field to build up,and squeezed amplitude to increase,and squeezed degree to deepen.",
        "keywords": [
            "2m-th power Y-squeezing",
            "injected multimode vacuum field",
            "quantum optics",
            "multimode squeezed state",
            "3MFSS light-field"
        ],
        "authors": [
            {
                "name": "XUE Hong",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China;Physics Department,Weinan Teachers College,Weinan,Shannxi ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Sciences,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2008
    },
    "Fe725Gbm": {
        "id": "Fe725Gbm",
        "title": "A new perspective for cardiorenal syndrome",
        "abstract": "The relationship between renal and cardiac diseases has been closely recognized in recent years.Recently,the concept of cardiorenal syndrome(CRS)is widely applied.From an epidemiological perspective,CRS is a common syndrome in hospital patients and associated with poor prognosis.Increasing evidences support the roles of central venous congestion,neurohormonal elaboration,anemia,oxidative stress,and renal sympathetic activity as potential contributors to this complex syndrome.This review stresses the epidemiology,pathophysiology and treatment of the CRS.",
        "keywords": [
            "Epidemiology",
            "Cardiorenal syndrome",
            "Pathologic physiology",
            "Treatment"
        ],
        "authors": [
            {
                "name": "LIANG Xin-ling",
                "org": "Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangdong ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,Guangdong Academy of Medical Sciences,Guangdong General Hospital,Guangdong ,China"
            }
        ],
        "venue": "Practical Journal of Clinical Medicine",
        "year": 2012
    },
    "T0MbCKa4": {
        "id": "T0MbCKa4",
        "title": "In vitro assessment of thyroid hormone disrupting activities in drinking water sources along the Yangtze River.",
        "abstract": "The thyroid hormone disrupting activities of drinking water sources from the lower reaches of Yangtze River were examined using a reporter gene assay based on African green monkey kidney fibroblast (CV-1) cells. None of the eleven tested samples showed thyroid receptor (TR) agonist activity. Nine water samples exhibited TR antagonist activities with the equivalents referring to Di-n-butyl phthalate (DNBP) (TR antagonist activity equivalents, ATR-EQ(50)s) ranging from 6.92 × 10(1) to 2.85 × 10(2) μg DNBP/L. The ATR-EQ(50)s and TR antagonist equivalent ranges (ATR-EQ(30-80) ranges) for TR antagonist activities indicated that the water sample from site WX-8 posed the greatest health risks. The ATR-EQ(80)s of the water samples ranging from 1.56 × 10(3) to 6.14 × 10(3) μg DNBP/L were higher than the NOEC of DNBP. The results from instrumental analysis showed that DNBP might be responsible for the TR antagonist activities in these water samples. Water sources along Yangtze River had thyroid hormone disrupting potential.",
        "keywords": [
            "thyroid receptor antagonist equivalent",
            "drinking water source",
            "reporter gene assay",
            "thyroid hormone disrupting activity",
            "thyroid receptor antagonist equivalent range"
        ],
        "authors": [
            {
                "name": "Xinxin Hu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Fengxian Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Fu Cao",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Guanjiu Hu",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Yingqun Hao",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xinru Wang",
                "org": "Nanjing Medical University(Nanjing Medical University),Nanjing,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Environmental pollution (Barking, Essex : 1987)",
        "year": 2013
    },
    "Tg1cdnGy": {
        "id": "Tg1cdnGy",
        "title": "Poling and characterization of nonlinear polymer DCNP/PEK-c thin films",
        "abstract": "Polyetherketone (PEK-c) guest–host polymer thin films doped with 3-(1,1-dicyanothenyl)-1-phenyl-4, 5-dihydro-1H-pryazole (DCNP) were prepared. The poling profiles of the polymer film were investigated by using the in situ second-harmonic generation (SHG) measurement. The corona poling condition was optimized by the poling profiles. The second-order nonlinear optical (NLO) coefficient χ 33 (2) =20.86 pm/V at λ=1064 nm was determined by using the Maker fringe method after poling under the optimal poling condition. The temperature stability of the second-order optical properties of the poled polymer film was measured by the in situ SHG intensity probing. Moreover, the relaxation of the electric field-induced polar orientation of the chromophores in the poled polymer film was measured by the thermally stimulated discharge current (TSDC) technique. Keywords A. Polymers, elastomers, and plastics D. Electronic transport D. Optical properties E. Nonlinear optics",
        "keywords": [
            "second harmonic generation",
            "thin film",
            "electric field",
            "nonlinear optics",
            "induced polarization",
            "electron transport",
            "second order"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": ""
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Zhiling Xu",
                "org": "State Key Laboratory for Materials Modification by Laser, Ion and Electron Beams, Department of Physics, Fu Dan University, Shanghai 200433, People's Republic of China"
            },
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Qintian Gu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Dong Xu",
                "org": "State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, People's Republic of China"
            },
            {
                "name": "Hongzheng Wei",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            },
            {
                "name": "Jinzhong Yu",
                "org": "Semiconductor Institute Region of State Key Laboratory on Integrated Optoelectronics, Chinese Academy of Science, Beijing 100083, People's Republic of China"
            }
        ],
        "venue": "Solid State Communications",
        "year": 2000
    },
    "HdofKih7": {
        "id": "HdofKih7",
        "title": "Micro-anatomic study of petroclival region by keyhole approach of suboccipital-retrosigmoid suprameatal",
        "abstract": "Objective To study the micro-anatomic structure of petroclival region via suboccipital-retrosigmoid suprameatal keyhole approach.Methods Ten formalin-fixed adult cadaveric heads(20 sides) were used for simulating suboccipital-retrosigmoid suprameatal keyhole approach to observe the structure of petroclival region.Results Via suboccipital-retrosigmoid suprameatal keyhole approach,petroclival region could be reached from post-lateral and the lateral side of cerebellar hemisphere,petrosal bone,cranial nerve(CN) Ⅴ,Ⅶ,Ⅷ,part of CN Ⅸ-Ⅻ,lateral side of the pons,petrosal vein,vertebral artery,anterior inferior cerebellavar artery and posterior inferior cerebellar artery were exposed clearly.The exposure of internal acoustic meatus was enlarged by stripping part of the petrosal bone.After discission of the tentorial,part of CN Ⅳ was exposed.Conclusion The suboccipital-retrosigmoid approach has an advantage of using a compatible hole to diminish the ineffective exposure of the brain with less damage and complication,which is an effective,safe and convenient way to resect the small tumor whose bulk located in the posterior cranial fossa.",
        "keywords": [
            "Suboccipital-retrosigmoid approach",
            "Anatomy of petroclival region"
        ],
        "authors": [
            {
                "name": "LI Zhengyi",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong , CHINA"
            },
            {
                "name": "SHI Wei",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong , CHINA"
            },
            {
                "name": "NI Lanchun",
                "org": ",et al.Department of Neurosurgery,Affiliated Hospital,Nantong University,Nantong , CHINA"
            }
        ],
        "venue": "Jiangsu Medical Journal",
        "year": 2009
    },
    "Mg2AYj8m": {
        "id": "Mg2AYj8m",
        "title": "Analysis and Optimizing Design For Matching Transmission Characteristics of Ultra-Fast Photoconductive Semiconductor Switches",
        "abstract": "The output of an ultra-fast photoconductive semiconductor switch(PCSS) is ultra-wideband electric pulses,so that the good design of transmission line from the switch to the load has a great effect upon the output waveforms.The coaxial-to-microstrip transition,a classic transition structure of planar PCSS,is analyzed in this paper.Considering the transient resistance of the linear-mode PCSS,the reflections of electromagnetic wave caused at the impedances discontinuity points are calculated.Its influences on the output waveform and on the voltage transmission efficiency are computed.And then,the contrasts are made with the real measured pulse waveforms,thus accounting for the shoulder peak phenomenon.Finally,in accordance with the simulation results,three kinds of optimized schemes of improving PCSS transmission characteristics are suggested.",
        "keywords": [
            "electric pulse",
            "photoconductive semiconductor switch",
            "transmission characteristic"
        ],
        "authors": [
            {
                "name": "WANG Xinmei",
                "org": "Faculty of Automation and Information Engineering,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "JI Weili",
                "org": "Faculty of Science,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Faculty of Science,Xi'an University of Technology,Xi'an ,China"
            },
            {
                "name": "ZHANG Miaomiao",
                "org": "Faculty of Science,Xi'an University of Technology,Xi'an ,China"
            }
        ],
        "venue": "Journal of Xi'an University of Technology",
        "year": 2013
    },
    "yJ6VuR1c": {
        "id": "yJ6VuR1c",
        "title": "GEOLOGICAL CHARACTERISTICS AND METALLOGENIC MODEL OF SUPER-LARGE KOUNRAD PORPHYRY COPPER DEPOSIT,KAZAKHSTAN",
        "abstract": "The Kounrad porphyry copper deposit was discovered 70 years ago in the Balkhash Metallogenic Belt of the Central Asian Metallogenic Domain,.It is a typical super-large porphyry copper deposit developed under the tectonic environment of continental margin arc,with a metallogenic model of granodiorite.The vertical and lateral zonings of the wall rock alteration and ore mineral assemblages are obviously observed in the deposit.High content ore in the leaching zone and the ore deposition at a very shallow depth made it easy to be mined.It is suggested that the metallogenesis of the deposit was controlled by the circular structure,and had a very close relation with the secondary quartzite and argillic alteration.",
        "keywords": [
            "porphyry copper deposit",
            "developing future",
            "Kounrad",
            "metallogenic model",
            "geological characteristics"
        ],
        "authors": [
            {
                "name": "HAN Shuqin",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijijng ,China"
            },
            {
                "name": "CHEN Xuanhua",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijijng ,China"
            },
            {
                "name": "YANG Nong",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijijng ,China"
            },
            {
                "name": "CHEN Zhengle",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijijng ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Institute of Geomechanics,Chinese Academy of Geological Sciences,Beijijng ,China"
            },
            {
                "name": "Ye Baoying",
                "org": "China University of Geosciences,Beijing ,China"
            }
        ],
        "venue": "Journal of Geomechanics",
        "year": 2010
    },
    "p9Jae8mM": {
        "id": "p9Jae8mM",
        "title": "Designing Power Analysis Resistant and High Performance Block Cipher Coprocessor using WDDL and Wave-Pipelining",
        "abstract": "Novel design method and design flow of block cipher is presented based on the WDDL(Wave Dynamic Differential Logic)and Wave-Pipelining techniques.This design flow utilized the current commercially available EDA tools to a large degree.The WDDL and wave-pipelining based coprocessor not only resists power analysis,but also achieves high performance and low power consumption in nature.According to the design flow,this paper implements a DES coprocessor.The simulation results show that the novel design method achieves high performance,low power consumption and power analysis resistant ability at the cost of chip area.",
        "keywords": [
            "design flow",
            "power analysis attack",
            "block cipher",
            "coprocessor",
            "high performance",
            "WDDL",
            "wave-pipelining"
        ],
        "authors": [
            {
                "name": "TONG Yuan-Man",
                "org": "School of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "WANG Zhi-Ying",
                "org": "School of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "DAI Kui",
                "org": "School of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "LU Hong-Yi",
                "org": "School of Computer,National University of Defense Technology,Changsha "
            },
            {
                "name": "SHI Wei",
                "org": "School of Computer,National University of Defense Technology,Changsha "
            }
        ],
        "venue": "Chinese Journal of Computers",
        "year": 2008
    },
    "iWOluf82": {
        "id": "iWOluf82",
        "title": "Karyotype analysis of the Calligonum mongolicum complex (Polygonaceae) from Northwest China",
        "abstract": "",
        "keywords": [
            "china",
            "idiogram",
            "chromosomes"
        ],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "borong pan",
                "org": ""
            }
        ],
        "venue": "Caryologia",
        "year": 2015
    },
    "SWPQZuBM": {
        "id": "SWPQZuBM",
        "title": "Solubility of Barite up to 250 °C and 1500 bar in up to 6 m NaCl Solution",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "amy t kan",
                "org": ""
            },
            {
                "name": "chunfang fan",
                "org": ""
            },
            {
                "name": "mason b tomson",
                "org": ""
            }
        ],
        "venue": "Industrial & Engineering Chemistry Research",
        "year": 2012
    },
    "xarDWuBP": {
        "id": "xarDWuBP",
        "title": "Electrochemical exfoliation of graphene-like two-dimensional nanomaterials",
        "abstract": "Unlike zero-dimensional quantum dots, one-dimensional nanowires/nanorods, and three-dimensional networks or even their bulk counterparts, the charge carriers in two-dimensional (2D) materials are confined along the thickness while being allowed to move along the plane. They have distinct characteristics like strong quantum confinement, tunable thickness, and high specific surface area, which makes them a promising candidate in a wide range of applications such as electronics, topological spintronic devices, energy storage, energy conversion, sensors, biomedicine, catalysis, and so on. After the discovery of the extraordinary properties of graphene, other graphene-like 2D materials have attracted a great deal of attention. Like graphene, to realize their potential applications, high efficiency and low cost industrial scale methods should be developed to produce high-quality 2D materials. The electrochemical methods usually performed under mild conditions are convenient, controllable, and suitable for mass production. In this review, we introduce the latest and most representative investigations on the fabrication of 2D monoelemental Xenes, 2D transition-metal dichalcogenides, and other important emerging 2D materials such as organic framework (MOF) nanosheets and MXenes through electrochemical exfoliation. The electrochemical exfoliation conditions of the bulk layered materials are discussed. The numerous factors which will affect the quality of the exfoliated 2D materials, the possible exfoliating mechanism and potential applications are summarized and discussed in detail. A summary of the discussion together with perspectives and challenges for the future of this emerging field is also provided in the last section.",
        "keywords": "",
        "authors": [
            {
                "name": "Yingchang Yang",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Hongshuai Hou",
                "org": "College of Chemistry and Chemical Engineering, Central South University,Changsha 410083,China"
            },
            {
                "name": "Guoqiang Zou",
                "org": "College of Chemistry and Chemical Engineering, Central South University,Changsha 410083,China"
            },
            {
                "name": "Wei Shi",
                "org": "College of Material and Chemical Engineering, Tongren University,Tongren 554300,China"
            },
            {
                "name": "Honglei Shuai",
                "org": "College of Chemistry and Chemical Engineering, Central South University,Changsha 410083,China"
            },
            {
                "name": "Jiayang Li",
                "org": "College of Chemistry and Chemical Engineering, Central South University,Changsha 410083,China"
            },
            {
                "name": "Xiaobo Ji",
                "org": "College of Chemistry and Chemical Engineering, Central South University,Changsha 410083,China"
            }
        ],
        "venue": "Nanoscale",
        "year": 2019
    },
    "nhn6fg2W": {
        "id": "nhn6fg2W",
        "title": "Dual Dimensions of Western Marxist Criticism of Modernity",
        "abstract": "Western Marxism criticizes modernity in dual dimensions:the temporal dimension and the spacial dimension,the unity of which represents the consistence of critical spirit of modernity with metaphysics of human reason.",
        "keywords": [
            "double dimensions",
            "Western Marxism",
            "criticism of modernity"
        ],
        "authors": [
            {
                "name": "Han Qiuhong",
                "org": ""
            },
            {
                "name": "Shi Wei",
                "org": ""
            }
        ],
        "venue": "Jiangsu Social Sciences",
        "year": 2010
    },
    "6HYYXxiY": {
        "id": "6HYYXxiY",
        "title": "Probucol combined with valsartan in immunoglobulin A nephropathy: A multi-centre, open labelled, randomized controlled study: Probucol plus valsartan and IgA nephropathy",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wenjian wang",
                "org": ""
            },
            {
                "name": "zonglin feng",
                "org": ""
            },
            {
                "name": "liping wang",
                "org": ""
            },
            {
                "name": "yongzheng liang",
                "org": ""
            },
            {
                "name": "honghong yan",
                "org": ""
            },
            {
                "name": "bin zhang",
                "org": ""
            },
            {
                "name": "yunfeng xia",
                "org": ""
            },
            {
                "name": "shuan hou",
                "org": ""
            },
            {
                "name": "weiqiang zhong",
                "org": ""
            },
            {
                "name": "xiaofeng shi",
                "org": ""
            },
            {
                "name": "haitang hu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "lixia xu",
                "org": ""
            },
            {
                "name": "li zhang",
                "org": ""
            },
            {
                "name": "zhiming ye",
                "org": ""
            }
        ],
        "venue": "Nephrology",
        "year": 2014
    },
    "wEw6pOHL": {
        "id": "wEw6pOHL",
        "title": "Advance in the Research of Abzyme",
        "abstract": "Catalytic antibody(also known as abzyme) is a kind of immunoglobulin with catalytic.Because it has high selectivity and amazing diversity as antibodies and highly catalytic as enzymes,it is anticipated that using abzyme preparation technology one can obtain any kind of tailor-made biocatalysts,including those not occurred in nature,for various kinds of practical application.Thus,abzyme study has an important value in theory and practice for biology,chemistry and research are summarized with a special emphasis on the breadth and scope of new antibody-catalyzed reactions and novel hapten design strategies.The advances of catalytic antibodies research are summarized with abzymes structure,of nature and their preparings,a method to produce and the filtering method,enzymology character and the latest progresses in catalytic antibodies.",
        "keywords": [
            "Abzymes",
            "Catalytic antibodies",
            "Enzymology character",
            "Selection"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Chengdu Vocational College of Agricultural Science and Technology,Chengdu ,China"
            }
        ],
        "venue": "Inner Mongolia Agricultural Science and Technology",
        "year": 2011
    },
    "zfteOHkH": {
        "id": "zfteOHkH",
        "title": "Multi-functional battery management system and its applications",
        "abstract": "For the research of paralleled battery characteristics,a new multi-functional battery management system(BMS) was developed,which could measure branch currents and calculate each paralleled battery's state-of-charge(SOC),and also could measure battery voltage and temperature,and communicate with other apparatus.The hardware and software structures of the BMS were introduced and its branch-current measured ability was highlighted in this paper.The voltage calibration principle and method were presented.Also,the results obtained in the paralleled battery characteristics research were discussed.At last,a battery life test platform was introduced,which validated the reliability and durability of BMS.",
        "keywords": [
            "parallel",
            "battery life",
            "branch current",
            "battery management system",
            "voltage calibration"
        ],
        "authors": [
            {
                "name": "LIN Si-qi",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "JIANG Jiu-chun",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "ZHANG Wei-ge",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            },
            {
                "name": "JIA Rong-da",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing ,China"
            }
        ],
        "venue": "Chinese Journal of Power Sources",
        "year": 2012
    },
    "DEu8JUw9": {
        "id": "DEu8JUw9",
        "title": "Design and Realization on the Experimental Personal Management System Based on J2EE",
        "abstract": "With the fast development and wide application of network technology,it is very necessary to build the system of enterprise personal management.A kind of enterprise personal management system is desighed based on the technical of J2EE,which adopts the most popular SSH framework of J2EE,uses Tomcat as application server,selects SQL Server2005 as the database and the system has good stability,development and to maintain.",
        "keywords": [
            "enterprise personal management",
            "SQL Server2005",
            "J2EE",
            "Tomcat"
        ],
        "authors": [
            {
                "name": "Liu Fangyu",
                "org": "1.Department of Physics,Taiyuan University of Technology,Taiyuan "
            },
            {
                "name": "Shi Wei",
                "org": " 2.College of Information Engineering,Taiyuan University of Technology,Taiyuan ,China"
            }
        ],
        "venue": "Journal of Taiyuan Normal University(Natural Science Edition)",
        "year": 2011
    },
    "ReH3o8zR": {
        "id": "ReH3o8zR",
        "title": "Mood and the Self-Esteem Memory Effect",
        "abstract": "The experiment replicated and verified the model of the self-esteem memory effect.It clarified that mood was an irrelevant variable that had an effect on selective memory,and the self-esteem memory effect was definitely the result of trait self-esteem.In addition,with regard to the negative self-referent information,the self-referent memory effect was not found.",
        "keywords": [
            "self-esteem",
            "self-esteem's memory effect",
            "mood",
            "self-referent effect"
        ],
        "authors": [
            {
                "name": "Shi Wei",
                "org": " School of Culture and Social Development Studies,Southwest University,Chongqing,"
            },
            {
                "name": "Huang Xiting",
                "org": " School of Psychology,Southwest University,Chongqing,"
            }
        ],
        "venue": "Psychological Science",
        "year": 2008
    },
    "IyRiWMox": {
        "id": "IyRiWMox",
        "title": "Coherent THz waves based on difference-frequency generation",
        "abstract": "",
        "keywords": [
            "second order",
            "gallium arsenide"
        ],
        "authors": [
            {
                "name": "yujie j ding",
                "org": "lehigh university"
            },
            {
                "name": "wei shi",
                "org": "lehigh university"
            }
        ],
        "venue": "",
        "year": 2003
    },
    "U1SenN0a": {
        "id": "U1SenN0a",
        "title": "The expression patterns of Septin-9 after traumatic brain injury in rat brain.",
        "abstract": "Septins are a novel group of GTPases, which are first identified in yeast and more recently found in a wide range of animal cells. Septin-9, a novel septin family member, is expressed ubiquitously and involved in an increasing number of signaling cascades. However, information regarding its distribution and possible function in the central nervous system (CNS) is limited. In this study, western blot analysis and immunohistochemistry showed a significant upregulation of Septin-9 in the ipsilateral peritrauma cortex compared with the sham group. Immunofluorescent labeling indicated that Septin-9 was localized strikingly in the cytoplasm of neurons, but not astrocytes and oligodendrocytes. The co-localization of Septin-9 and active caspase-3 was also examined in the ipsilateral cortex. In addition, the expression patterns of active caspase-3 were parallel with that of Septin-9. Quantitative real-time RT-PCR also was used to detect Seption-9 mRNA level. Based on our data, we speculated that traumatic brain injury may be a stimulus to induce the Septin-9 expression, and Septin-9 might play an important role in the pathophysiology process in the CNS after traumatic brain injury. Taken together, this is the first description of Septin-9 expression changes during the central nervous system lesion and repair, but further studies are needed to understand the cell signaling pathway which can direct the exact role of Septin-9 following traumatic brain injury.",
        "keywords": [
            "Septin-9",
            " Traumatic brain injury",
            " Apoptosis",
            " Rat"
        ],
        "authors": [
            {
                "name": "Hui Mao",
                "org": "Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, 226001, People's Republic of China."
            },
            {
                "name": "Jiao Liu",
                "org": "Department of Public Health,Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Wei Shi",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Qingfeng Huang",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Xide Xu",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Lanchun Ni",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Feihui Zou",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Jinlong Shi",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Debao Li",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Yonghua Liu",
                "org": "Department of Microbiology and Immunology,Medical College, Nantong University,Nantong,People’s Republic of China"
            },
            {
                "name": "Jian Chen",
                "org": "Department of Neurosurgery,Affiliated Hospital of Nantong University,Nantong,People’s Republic of China"
            }
        ],
        "venue": "Journal of molecular neuroscience : MN",
        "year": 2013
    },
    "vcpYvZ2M": {
        "id": "vcpYvZ2M",
        "title": "Engineered Molecular Chain Ordering in Single-Walled Carbon Nanotubes/Polyaniline Composite Films for High-Performance Organic Thermoelectric Materials.",
        "abstract": "Single-walled carbon nanotubes (SWNTs)/polyaniline (PANI) composite films with enhanced thermoelectric properties were prepared by combining insitu polymerization and solution processing. Conductive atomic force microscopy and X-ray diffraction measurements confirmed that solution processing and strong - interactions between the PANI and SWNTs induced the PANI molecules to form a highly ordered structure. The improved degree of order of the PANI molecular arrangement increased the carrier mobility and thereby enhanced the electrical transport properties of PANI. The maximum in-plane electrical conductivity and power factor of the SWNTs/PANI composite films reached 1.44x10(3)Scm(-1) and 217Wm(-1)K(-2), respectively, at room temperature. Furthermore, a thermoelectric generator fabricated with the SWNTs/PANI composite films showed good electric generation ability and stability. A high power density of 10.4Wcm(-2)K(-1) was obtained, which is superior to most reported results obtained in organic thermoelectric modules.",
        "keywords": [
            "composite materials",
            "pi interactions",
            "nanostructures",
            "carbon nanotubes",
            "thermoelectric materials"
        ],
        "authors": [
            {
                "name": "Liming Wang",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Juanxiu Xiao",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Kaiyang Zeng",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qun Wang",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "CHEMISTRY-AN ASIAN JOURNAL",
        "year": 2016
    },
    "y7F6ohhK": {
        "id": "y7F6ohhK",
        "title": "Synthesis and characterization of thiazolylazo chromophore for nonlinear optical applications",
        "abstract": "Bathochromic thiazolylazo second-order nonlinear optical chromophore, having 2-hydroxylethyl group in a molecule, has been prepared. The temperature decomposition of the chromophore was measured by differential scanning calorimetry (DSC). The second-order polarizabilities at zero energy and the dispersion of second-order polarizabilities were measured by solvatochromic method. The other parameters of the chromophore were also measured.",
        "keywords": [
            "solvatochromic method",
            "hyperpolarizability",
            "78.20",
            "73.61",
            "nonlinear optical material",
            "78.40",
            "thiazolylazo chromophore",
            "differential scanning calorimetry",
            "nonlinear optics",
            "second order"
        ],
        "authors": [
            {
                "name": "Qiwei Pan",
                "org": "State Key Laboratory, Institute of Crystal Materials, Shandong University, Jinan 250100, China"
            },
            {
                "name": "Zhenyu Zhang",
                "org": "Chemistry and Environment Department of Shandong University, Jinan 250100, China"
            },
            {
                "name": "Changshui Fang",
                "org": "State Key Laboratory, Institute of Crystal Materials, Shandong University, Jinan 250100, China"
            },
            {
                "name": "Wei Shi",
                "org": "State Key Laboratory, Institute of Crystal Materials, Shandong University, Jinan 250100, China"
            },
            {
                "name": "Qingtian Gu",
                "org": "State Key Laboratory, Institute of Crystal Materials, Shandong University, Jinan 250100, China"
            },
            {
                "name": "Xiangwen Wu",
                "org": "State Key Laboratory, Institute of Crystal Materials, Shandong University, Jinan 250100, China"
            }
        ],
        "venue": "Materials Letters",
        "year": 2001
    },
    "VHima40l": {
        "id": "VHima40l",
        "title": "Research on Three-Phase Four-Wire APF Control Strategy Based on GPC",
        "abstract": "Focusing on the problem of the reduction that active power fifter(APF) compensating ability caused by the system inherit time propagation delay of APF,this paper gave a control strategy based on generalized predictive conlrol(GPC).The GPC model and the CARIMA model of three-phase four-wire APF were designed on which the predictable current control of the three-phase four-wire APF was achieved.The optimized control rules were designed.The simulation results prove that the GPC strategy has the benefit of good tracing capacity and eliminates the current glitch on the network side.",
        "keywords": [
            "generalized predictive control(GPC)",
            "active power filter(APF)",
            "three-phase four-wire"
        ],
        "authors": [
            {
                "name": "HUANG Chuanjin",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            },
            {
                "name": "CHEN Tiejun",
                "org": "School of Electrical Engineering,Zhengzhou Univrsity,Zhengzhou ,China"
            },
            {
                "name": "SONG Haijun",
                "org": "School of Engineering Technology,Zhongzhou University,Zhengzhou ,China"
            }
        ],
        "venue": "Low Voltage Apparatus",
        "year": 2012
    },
    "idWJVk33": {
        "id": "idWJVk33",
        "title": "Huoxuehuayu Act on the Treatment of Refractory Nephrotic Syndrome",
        "abstract": "From the Chinese medicine medical therapy (basic addition and subtraction to treatment, Traditional Chinese Medicine Research) outside the therapy of Chinese medicine, acupuncture therapy and evaluation with the vision, huoxuehuayu Act on the Treatment of refractory nephrotic syndrome. Pointed out:blood in clinical use is widely, but is still a lack of multicenter, large sample, randomized study of systemic lupus.",
        "keywords": [
            "refractory nephrotic syndrome",
            "promoting blood circulation by removing blood stasis"
        ],
        "authors": [
            {
                "name": "Liang Li-feng",
                "org": "Guangxi Traditional Chinese Medicine College First Affiliated Hospital,Nanning ,Guangxi,China"
            },
            {
                "name": "Shi Wei",
                "org": "Guangxi Traditional Chinese Medicine College First Affiliated Hospital,Nanning ,Guangxi,China"
            },
            {
                "name": "Zhao Jun-ya",
                "org": "Guangxi Traditional Chinese Medicine College First Affiliated Hospital,Nanning ,Guangxi,China"
            }
        ],
        "venue": "Journal of Practical Traditional Chinese Internal Medicine",
        "year": 2009
    },
    "aUkYuvUj": {
        "id": "aUkYuvUj",
        "title": "Introduction of EDC580 Dynamic Controller and Software Design",
        "abstract": "The characteristics of EDC580 dynamic controller and the method for test software design are introduced,and the main interface functions are discussed in detail.",
        "keywords": [
            "API",
            "VISUALBASIC",
            "dynamic test software",
            "EDC580"
        ],
        "authors": [
            {
                "name": "Li Manchang",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Shi Wei",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Sun Jian",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Jiang Lihua",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            },
            {
                "name": "Wang Yan",
                "org": "Changchun Research Institute for Mechanical Science Co.,Ltd.Changchun ,Jilin,China"
            }
        ],
        "venue": "Engineering & Test",
        "year": 2011
    },
    "PRi0jOx7": {
        "id": "PRi0jOx7",
        "title": "The value of AKICS score for the prediction of acute kidney injury after cardiac surgery in Chinese elderly patients",
        "abstract": "Objective The purpose of present study was to externally validate AKICS score for acute kidney injury(AKI) after cardiac surgery in Chinese elderly patients.Method We conducted a retrospective research in patients undergoing coronary artery bypass grafting surgery and(or) valve replacement in our center between January 1,2007 and December 31,2009.The primary outcome was AKI according to RIFLE criteria.The baseline serum creatinine was defined as the latest serum creatinine before surgery.For evaluation of the performance of the model,discrimination and calibration of AKICS score were measured in elderly patients undergoing surgery and those who did not expose contrast media within 7 days prior to surgery.Results Among 227 patients included in the present study,141 patients did not expose contrast media within 7 days before surgery.In the 227 elderly patients and the 141 patients who did not expose contrast media within 7 days before surgery,the incidence of AKI was 63.9%(145/227) and 66.7%(94/141),respectively.In the 227 elderly patients,the discrimination of score using the area under the receiver operating characteristic(ROC) curve was 0.702(95%CI 0.631～0.772),and the calibration using Hosmer-Lemeshow goodness-of-fit test was 0.704.In the 141 patients who did not expose contrast media within 7 days before surgery,the area under ROC was 0.764(95% CI 0.684 ～ 0.844),and the calibration was 0.906.Conclusion AKICS score offers better performance and accurately predicts AKI according to RIFLE criteria in elderly patients undergoing cardiac surgery.This scoring model is more suitable for elderly patients who did not expose contrast media within 7 days before cardiac surgery.",
        "keywords": [
            "Cardiac surgery",
            "Acute kidney injury",
            "Elderly",
            "AKICS score"
        ],
        "authors": [
            {
                "name": "HU Peng-hua",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China.;Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "CHEN Yuan-han",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China."
            },
            {
                "name": "LIANG Xin-ling",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China."
            },
            {
                "name": "LI Rui-zhao",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China."
            },
            {
                "name": "LI Zhi-lian",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China."
            },
            {
                "name": "JIANG Fen",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China.;Southern Medical University,Guangzhou ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Division of Nephrology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou ,China."
            }
        ],
        "venue": "Chinese Journal of Blood Purification",
        "year": 2013
    },
    "I46rwTyc": {
        "id": "I46rwTyc",
        "title": "WIDELY-TUNABLE, MONOCHROMATIC, AND HIGH-POWER TERAHERTZ SOURCES AND THEIR APPLICATIONS",
        "abstract": "",
        "keywords": [
            "terahertz",
            "second order",
            "conversion efficiency",
            "absorption coefficient"
        ],
        "authors": [
            {
                "name": "yujie j ding",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "Journal of Nonlinear Optical Physics & Materials",
        "year": 2012
    },
    "ujohg9ta": {
        "id": "ujohg9ta",
        "title": "Effect of Shenkang-Ⅱ on Hypothalamo-pituitary-adrenal Axis in Nephrotic Syndrome Rats during Glucocorticoids Withdrawal",
        "abstract": "Objective To observe the effect of Shenkang-Ⅱ on hypothalamus-pituitary-adrenal axis (HPA axis) in nephrotic syndrome rats during high-dose glucocorticoids withdrawal, and provide a theoretical basis for clinical application of Shenkang-Ⅱ during the withdrawing and maintaining stages of glucocorticoids in the treatment of nephrotic syndrome. Methods The models of nephrotic syndrome in rats were established with adriamycin, and treated with high-dose glucocorticoid which can cause HPA axis suppression. After the HPA axis was suppressed, the hormone was reduced gradually. At the same time, the rats were treated by intragastric administration with different doses of Shenkang-Ⅱ. The changes of serum ACTH, cortisol and adrenal morphological in large dose of Shenkang-Ⅱ group, small dose of Shenkang-Ⅱ group, hormone control group, nephrotic syndrome model group and normal group were observed after two weeks. Results In the stage of withdrawing glucocorticoids, there were some amelioration in the changes of serum ACTH, cortisol in every group. After 2 weeks, those changes didn’t return to normal level. However, compared with the level of hormone control group, there were obvious increases in the levels of serum ACTH and cortisol in the large and small dose of Shenkang-Ⅱ group (P <0.05), and levels of serum ACTH and cortisol in the large dose of Shenkang-Ⅱ group ameliorated obviously than that in the small dose of Shenkang-Ⅱ group (P <0.05). In the Shenkang-Ⅱ treatment group, there were less atrophy in fascicular zone of adrenal cortex and less cell arrangement disorder in adrenal gland, and the amelioration of morphology was more in the large dose of Shenkang-Ⅱ group than that in the small dose of Shenkang-Ⅱ group. Conclusion Shenkang-Ⅱ can improve the suppressive effect of glucocorticoids on the HPA axis, indicating that we may prolong the course of treatment and increase the dose properly in clinic.",
        "keywords": [
            "cortisol",
            "hypothalamo-pituitary-adrenal axis",
            "rat",
            "adrenocorticotropic hormone",
            "Shenkang-Ⅱ"
        ],
        "authors": [
            {
                "name": "CHEN Yan-qiang",
                "org": "Guangxi College of TCM, Nanning , China"
            },
            {
                "name": "HUANG Yu-yin",
                "org": "Guangxi College of TCM, Nanning , China"
            },
            {
                "name": "SHI Wei",
                "org": "The First Hospital Affiliated to Guangxi TCM College, Nanning , China"
            }
        ],
        "venue": "Chinese Journal of Information on Traditional Chinese Medicine",
        "year": 2010
    },
    "JYsItleF": {
        "id": "JYsItleF",
        "title": "A Meta-analysis on Randomized Controlled Trials of Statins to Prevent Atrial Fibrillation",
        "abstract": "Objective To synthesize the available evidence on the efficacy of using statins in the prevention of recurrent and new-onset atrial fibrillation(AF).Methods We searched PubMed,EMbase,EMB Reviews-Cochrane Central Register of Controlled Trials(Issue 3,2007),CBMdisc,VIP,and CNKI databases from establishment to 15th Sep. 2007 to identify randomized controlled trials(RCTs)covering the use of statins for the patients with persistent AF after electrical cardioversion,paroxysmal and postoperative AF.Meta-analysis was performed using RevMan 4.3 software after the strict evaluation of the methodological quality of the included RCTs.Results Five RCTs including 470 patients were included.Significant heterogeneity was found when the data were pooled,so a random effect model was used for meta- analysis.Compared with placebo or no use of statins,the statins decreased risk of AF recurrence and postoperative AF (RR=0.61,95%CI 0.43 to 0.88,P=0.008).Sensitivity analysis showed that the result was stable.The fail-safe number was 52.91.Conclusion The statins may decrease incidence of AF recurrence and postoperative AF.Because of the low quality and the small number of included studies,larger sample-size,randomized,double-blinded controlled trials are needed.",
        "keywords": [
            "Statins",
            "Meta-analysis",
            "Atrial fibrillation"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": " Department of Cardiology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "LIU Zeng-zhang",
                "org": " Department of Cardiology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "SU Li",
                "org": " Department of Cardiology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing ,China"
            },
            {
                "name": "YIN Yue-hui",
                "org": " Department of Cardiology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing ,China"
            }
        ],
        "venue": "Chinese Journal of Evidence-Based Medicine",
        "year": 2009
    },
    "Q1D2hFOn": {
        "id": "Q1D2hFOn",
        "title": "Primary study of using confocal endoscopy in diagnosis of mucosal lesions in upper gastrointestinal tract",
        "abstract": "[Objective] To explore the possibility of diagnosing mucosal lesions in upper gastrointestinal tract by confocal endoscopy. [Methods] Nine patients underwent confocal gastroendoscopy were involved in the study. Normal mucosa and suspected lesions were observed by confocal endoscopy and compared with corresponding histopathological results. [Results] 1587 confocal images were captured from 74 sites, which included 39 sites of normal mucosa, 31 sites of chronic gastritis, 3 sites of esophageal squamous cell carcinoma and 1 site of ectopic gastric mucosa in esophagus. Different sites and lesions had corresponding morphological features by confocal endoscopy. The sensitivity, specificity and accuracy in the diagnosis of intestinal metaplasia of gastric mucosa were 85.7%, 95.8% and 93.5%, respectively. [Conclusion] Confocal endoscopy may display the histological and cytological features of the upper gastrointestinal tract mucosa. It is a valuable method for the diagnosis of intestinal metaplasia of gastric mucosa.",
        "keywords": [
            "confocal",
            "endoscopy",
            "upper gastrointestinal tract",
            "mucosal lesion"
        ],
        "authors": [
            {
                "name": "SUN Xiao-bin",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "LI Yu",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "WANG Qiong",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "XI Wei-dong",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "YUAN De-qiang",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "NONG Chun-yan",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            },
            {
                "name": "YANG Xiu-lan",
                "org": "Department of Gastroenterology, the Third People′s Hospital of Chengdu, Chengdu, Sichuan , P.R.China"
            }
        ],
        "venue": "China Journal of Endoscopy",
        "year": 2008
    },
    "5GpxzpWx": {
        "id": "5GpxzpWx",
        "title": "Occurrence and potential causes of androgenic activities in source and drinking water in China.",
        "abstract": "The increased incidences of disorders of male reproductive tract as well as testicular and prostate cancers have been attributed to androgenic pollutants in the environment. Drinking water is one pathway of exposure through which humans can be exposed. In this study, both potencies of androgen receptor (AR) agonists and antagonists were determined in organic extracts of raw source water as well as finished water from waterworks, tap water, boiled water, and poured boiled water in eastern China. Ten of 13 samples of source water exhibited detectable AR antagonistic potencies with AR antagonist equivalents (Ant-AR-EQs) ranging from <15.3 (detection limit) to 140 μg flutamide/L. However, no AR agonistic activity was detected in any source water. All finished water from waterworks, tap water, boiled water, and poured boiled water exhibited neither AR agonistic nor antagonistic activity. Although potential risks are posed by source water, water treatment processes effectively removed AR antagonists. Boiling and pouring of water further removed these pollutants. Phthalate esters (PAEs) including diisobutyl phthalate (DIBP) and dibutyl phthalate (DBP) were identified as major contributors to AR antagonistic potencies in source waters. Metabolites of PAEs exhibited no AR antagonistic activity and did not increase potencies of PAEs when they coexist.",
        "keywords": [],
        "authors": [
            {
                "name": "Xinxin Hu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Si Wei",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Xiaowei Zhang",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Jianfang Feng",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Guanjiu Hu",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "Sulan Chen",
                "org": "Jiangsu Provincial Environmental Monitoring Center(Jiangsu Provincial Environmental Monitoring Center),Nanjing,China"
            },
            {
                "name": "John P Giesy",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            },
            {
                "name": "Hongxia Yu",
                "org": "Nanjing University(Nanjing University),Nanjing,China"
            }
        ],
        "venue": "Environmental science & technology",
        "year": 2013
    },
    "DrPuEbYh": {
        "id": "DrPuEbYh",
        "title": "p38 MAPK signal transduction pathways involved in MMP2 expression in rat mesangial cells",
        "abstract": "Objective To investigate the signal transduction pathways involved in matrix metalloproteinases-2 in rat mesangial cell.Methods Rat mesangial cells were cultured using routine.The effects of p38 inhibitor SB203580,MEK inhibitor U0126,extracellular signal-regulated kinase(ERK) inhibitor PD098059,phosphatidylinositaol 3-kinase(PI3K) inhibitor LY294002,and tyrosine kinase inhibitor herbimycin A on production and secretion of MMP-2 in mesangial cell were determined by gelatin zymography,semiquantitative reverse transcriptase(RTPCR) and Western blot.Results The p38 inhibitor SB203580 depressed MMP-2 production by about 25% at a 72-hour culture(P<0.05),but MEK inhibitor U0126,extracellular signal-regulated kinase(ERK) inhibitor PD098059,phosphatidylinositaol 3-kinase(PI3K) inhibitor LY294002,and tyrosine kinase inhibitor herbimycin A didn't affect the activity,protein and gene expression of MMP-2 in masangial cell.When concentrations of SB203580 were 10,20,30,and(40 μmol/L) in different groups,the ratios of MMP-2 depression were 7.2%,13.5%,21.3%,and 28% at 48 hours respectively.Conclusion p38 MAPK signal transduction pathways may be involved in the production of matrix metalloproteinases-2,and have dose-dependen regulation production of MMP-2 in mesangial cell.",
        "keywords": [
            "matrix metalloproteinases",
            "masangial cell",
            "signal transduction pathways",
            "p38MAPK"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou ,China"
            },
            {
                "name": "LIU Shuang-xin",
                "org": "Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou ,China"
            },
            {
                "name": "WANG Wen-jian",
                "org": "Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou ,China"
            },
            {
                "name": "YE Zhi-ming",
                "org": "Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou ,China"
            },
            {
                "name": "LIANG Yong-zheng",
                "org": "Department of Nephrology,Guangdong Provincial People's Hospital,Guangzhou ,China"
            }
        ],
        "venue": "Basic Medical Sciences and Clinics",
        "year": 2005
    },
    "mBE01S2e": {
        "id": "mBE01S2e",
        "title": "The complete mitochondrial genome of Solea ovata (Pleuronectiformes: Soleidae).",
        "abstract": "Solea ovata (Pleuronectiformes: Soleidae) is characterized by eyes on right side and an ovata body with small ctenoid scales on both sides. In this article, the complete mitogenome of Solea ovata was first determined. The total length is 16,782 bp, containing 13 protein-coding genes, 22 tRNA genes, and 2 rRNA genes (12S and 16S), as well as a putative control region and a L-strand replication origin (OL). Except eight tRNA and ND6 genes, all other mitochondrial genes are encoded on the heavy strand. Overall base composition is 29.2% A, 29.4% C, 15.9% G, and 25.5% T with a slight AT bias of 54.7%. The determination of S. ovata complete mitogenome could contribute to understanding the systematic evolution of the genus Solea and further phylogenetic study on Soleidae and Pleuronectiformes.",
        "keywords": [
            "complete mitochondrial genome",
            "flatfish",
            "ovate sole"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Marine Bio-resources Sustainable Utilization, Marine Biodiversity Collection of South China Sea, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou , China and."
            },
            {
                "name": "Li Gong",
                "org": ""
            },
            {
                "name": "Shu-Ying Wang",
                "org": ""
            },
            {
                "name": "Xiao-Yu Kong",
                "org": ""
            }
        ],
        "venue": "Mitochondrial DNA",
        "year": 2014
    },
    "HjlXxWal": {
        "id": "HjlXxWal",
        "title": "Design of intelligent control system of solar street light",
        "abstract": "In order to better use and promote solar as a kind of green clean energy,in this paper a solar street light intelligent control system was designed,describing its hardware components,software and test process in detail.At first,in order to guarantee the full charge of battery in a short time in rainy days,the photosensitive resistor was used to realize the real time track of sunlight.Secondly,the light control and time control were used together to avoid the susceptibility of light control method to interference and the frequent time sets of the time control method.To save energy,the light was turned off according to the time setting,when there were few passersby in deep night,and turned on in early morning when there were more passersby.Finally,the overcharge and overdischarge protection strategies was designed to improve battery life.The actual tests prove that the error of automatic sun tracking is within 2 degrees,and the battery charge and discharge voltage is controlled strictly within the range setting.The system has some reference and promotion value.",
        "keywords": [
            "automatic tracking",
            "charging strategy",
            "intelligent control",
            "solar"
        ],
        "authors": [
            {
                "name": "LI Li-li",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin Liaoning ,China"
            },
            {
                "name": "SHI Wei",
                "org": "School of Electronics and Information Engineering,Liaoning Technical University,Fuxin Liaoning ,China"
            }
        ],
        "venue": "Chinese Journal of Power Sources",
        "year": 2012
    },
    "zjUgXuIo": {
        "id": "zjUgXuIo",
        "title": "Design of Li-Ion battery pack charging in trolleybus",
        "abstract": "By analyzing the inadequacies of using the traditional charging mode in trolleybus to charge Li-Ion battery pack,a charging mode that the car charger is controlled by battery management system is proposed.Battery management system collects and analysis data on Li-ion battery pack to obtain charging allowed signal,charging current,charging limit voltage and other information,exchanges data with car charger through CAN bus to control car charger to charge Li-ion battery pack safely and quickly.",
        "keywords": [
            "charge control",
            "battery management system",
            "Li-ion battery pack",
            "trolley bus"
        ],
        "authors": [
            {
                "name": "ZHANG Jin-ling",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "ZHANG Wei-ge",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "JIANG Jiu-chun",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            },
            {
                "name": "SHI Wei",
                "org": "School of Electrical Engineering,Beijing Jiaotong University,Beijing "
            }
        ],
        "venue": "Chinese Battery Industry",
        "year": 2010
    },
    "m1cS9U45": {
        "id": "m1cS9U45",
        "title": "The complete mitochondrial genome sequence of Siganus sutor (Perciformes: Siganidae)",
        "abstract": "AbstractThe complete mitochondrial genome of a marine fish Siganus sutor was completely sequenced by the high throughput sequencing method. This complete mitochondrial genome was 16,497 bp in length, consisted of 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one large non-coding region. The gene arrangement of S. sutor is identical to those in typical fishes. Phylogenetic tree based on 13 protein-coding genes shows that Siganidae has a closer phylogenetic relationship to Luvaridae than to Ephippidae or Scatophagidae.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Wei Shi",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            },
            {
                "name": "Shixi Chen",
                "org": " CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology Chinese Academy of Sciences, Guangzhou, China"
            },
            {
                "name": "Hui Yu",
                "org": " College of Life Science, Foshan University, Foshan, Guangdong, China; "
            }
        ],
        "venue": "Mitochondrial DNA Part B",
        "year": 2018
    },
    "JA8iAEPf": {
        "id": "JA8iAEPf",
        "title": "Modeling the Thermodynamic Properties of Common Minerals at High Temperature, Pressure and Salinity with Complex Ions",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "mason b tomson",
                "org": ""
            },
            {
                "name": "amy t kan",
                "org": ""
            },
            {
                "name": "chunfang fan",
                "org": ""
            },
            {
                "name": "nan zhang",
                "org": ""
            },
            {
                "name": "haiping lu",
                "org": ""
            },
            {
                "name": "wei shi",
                "org": ""
            }
        ],
        "venue": "open source systems",
        "year": 2012
    },
    "aUhXv25j": {
        "id": "aUhXv25j",
        "title": "Mesoporous Ni-P nanocatalysts for alkaline urea electrooxidation",
        "abstract": "Abstract   Mesoporous nickel phosphide (Ni-P) nanocatalysts have been synthesized via a facile solvothermal strategy and used for urea electrooxidation in alkaline medium. The physicochemical properties and electrocatalytic performances have been investigated. Due to the structural effect and electronic effect, the Ni-P nanocatalysts achieve a lower overpotential, higher activity and better stability compared with the Ni nanocatalysts. Therefore, an onset oxidation potential of 1.37 V (vs. RHE), a peak current density of 70 mA cm −2  and a good current retention of 58% for 1000 s at 1.52 V have been achieved by the Ni-P nanocatalysts, which show enhanced performance compared to the Ni nanocatalysts (1.42 V, 62 mA cm −2 , 39% retention), indicating a promising application of the mesoporous Ni-P nanocatalysts towards alkaline urea electrooxidation.",
        "keywords": "",
        "authors": [
            {
                "name": "Rui Ding",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Xudong Li",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Qilei Xu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Luo Wang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Haixia Jiang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Zeng Yang",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            },
            {
                "name": "Enhui Liu",
                "org": "Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Hunan 411105, PR China"
            }
        ],
        "venue": "Electrochimica Acta",
        "year": 2016
    },
    "bUkpp9q4": {
        "id": "bUkpp9q4",
        "title": "Immunotoxicity of nanoparticle nTiO 2 to a commercial marine bivalve species, Tegillarca granosa.",
        "abstract": "The increasing production and extensive application of nanoparticles (NPs) inevitably leads to increased release of NPs into the marine environment and therefore poses a potential threat to marine organisms, especially the sessile benthic bivalves. However, the impacts of NPs on the immunity of commercial and ecological important bivalve species, Tegillarca granosa, still remain unknown to date. In addition, the molecular mechanism of the immunotoxicity of NPs still remains unclear in marine invertebrates. Therefore, the immunotoxicity of nTiO exposure to T. granosa at environmental realistic concentrations was investigated in the present study. Results obtained showed that the total number, phagocytic activity, and red granulocytes ratio of the haemocytes were significantly reduced after 30 days nTiO exposures at the concentrations of 10 and 100 μg/L. Furthermore, the expressions of genes encoding Pattern Recognition Receptors (PPRs) and downstream immune-related molecules were significantly down-regulated by nTiO exposures, indicating a reduced sensitivity to pathogen challenges. In conclusion, evident immunotoxicity of nTiO to T. granosa at environmental realistic concentrations was detected by the present study. In addition, the gene expression analysis suggests that the PRRs (both TLRs and RIG1 investigated) may be the molecules for NPs recognition in marine invertebrates.",
        "keywords": [
            "Blood clam",
            "Gene expression",
            "Immunotoxicity",
            "Nanoparticles",
            "Pattern Recognition Receptors"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yu Han",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Cheng Guo",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Xinguo Zhao",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Saixi Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Wenhao Su",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Shanjie Zha",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Yichen Wang",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China."
            },
            {
                "name": "Guangxu Liu",
                "org": "College of Animal Sciences, Zhejiang University, Hangzhou, PR China. Electronic address: guangxu_liu@zju.edu.cn."
            }
        ],
        "venue": "Fish & shellfish immunology",
        "year": 2017
    },
    "QjaYiamn": {
        "id": "QjaYiamn",
        "title": "Ripple Effects of CEO Awards: Investigating the Acquisition Activities of Superstar CEOs' Competitors",
        "abstract": "Research SummaryThis study proposes that CEOs may undertake intensive acquisition activities to increase their social recognition and status after witnessing their competitors’ winning CEO awards. Using a sample of U.S. Su0026P 1500 firm CEOs, we find that CEOs engage in more intensive acquisition activities in the period after their competitors won CEO awards (i.e., post-award period), compared to the pre-award period. Moreover, this effect is stronger when focal CEOs themselves had a high likelihood of winning CEO awards. Our findings also show that acquisitions by focal CEO firms in the post-award period realize lower announcement returns compared to acquisitions by the same CEOs in the pre-award period.Managerial SummaryEach year a few CEOs receive CEO awards from business media and CEOs who receive such awards become instant celebrities, i.e., superstar CEOs. This study explores how superstar CEOs’ competitors react to not winning CEO awards. We find that superstar CEOs’ competitors undertake more intensive acquisition activities in the post-award period compared to the pre-award period. This is particularly true for competitors who were close yet did not win CEO awards. In addition, acquisitions by superstar CEOs’ competitors are associated with lower announcement returns in the post-award compared to the pre-award period. These findings collectively indicate that acquisitions may be used as a channel for superstar CEOs’ competitors to elevate their own social status, but at a cost to shareholders.",
        "keywords": "",
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Kelley School of Business Indiana University Indianapolis Indiana"
            },
            {
                "name": "Yan Zhang",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas"
            },
            {
                "name": "Robert E. Hoskisson",
                "org": "Jesse H. Jones Graduate School of Business Rice University Houston Texas"
            }
        ],
        "venue": "Strategic Management Journal",
        "year": 2017
    },
    "nkYbTsH1": {
        "id": "nkYbTsH1",
        "title": "Study on the Testing Technology of the Circuit Board in Digital Computer System of Certain Equipment",
        "abstract": "This paper designs a tester for the circuit board of the digital computer system, and puts forward a method for testing the circuit board based on the fault diagnosis.",
        "keywords": [
            "circuit board",
            "GAL",
            "testing technology",
            "digital computer system"
        ],
        "authors": [
            {
                "name": "LIU Jian-zhong",
                "org": ""
            },
            {
                "name": "SHI Wei",
                "org": ""
            },
            {
                "name": "PENG Shun-tang",
                "org": ""
            }
        ],
        "venue": "Sci-Tech Information Development & Economy",
        "year": 2008
    },
    "lF6IKxcu": {
        "id": "lF6IKxcu",
        "title": "Light controlled prebreakdown characteristics of a semi-insulating GaAs photoconductive switch",
        "abstract": "A 4 mm gap semi-insulating (SI) GaAs photoconductive switch (PCSS) was triggered by a pulse laser with a wavelength of 1064 nm and a pulse energy of 0.5 mJ. In the experiment, when the bias field was 4 kV, the switch did not induce self-maintained discharge but worked in nonlinear (lock-on) mode. The phenomenon is analyzed as follows: an exciton effect contributes to photoconduction in the generation and dissociation of excitons. Collision ionization, avalanche multiplication and the exciton effect can supply carrier concentration and energy when an outside light source was removed. Under the combined influence of these factors, the SI-GaAs PCSS develops into self-maintained discharge rather than just in the light-controlled prebreakdown status. The characteristics of the filament affect the degree of damage to the switch. © 2011 Chinese Institute of Electronics.",
        "keywords": [
            "exciton effect",
            "light controlled prebreakdown",
            "photo activated charge domain",
            "self-maintained discharge"
        ],
        "authors": [
            {
                "name": "Xiangrong Ma",
                "org": "Xinjiang Normal University(Xinjiang Normal University),Urumqi,China"
            },
            {
                "name": "Wei Shi",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Weili Ji",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            },
            {
                "name": "Hong Xue",
                "org": "Xi'an University of Technology(Xi'an University of Technology,Xi'an Univ. of Technol.),Xi An,China"
            }
        ],
        "venue": "Journal of Semiconductors",
        "year": 2011
    },
    "CGPBcLEy": {
        "id": "CGPBcLEy",
        "title": "Optimizing the Thermoelectric Performance of Poly(3-hexylthiophene) through Molecular-Weight Engineering",
        "abstract": "Poly(3-hexylthiophene) (P3HT) films with various molecular weights (MWs) were successfully prepared, and both their molecular structures and thermoelectric (TE) properties were investigated. It was found that the molecular weight of P3HT had an important effect on the carrier-transport properties by affecting the molecular structure and, as a result, also had an effect on the TE performance. The electrical conductivity of the P3HT films first increased upon increasing the molecular weight and then decreased at high molecular weights, whereas the Seebeck coefficient remained at the same level. As a result, the P3HT-M-50k (MW approximate to 50 000 g mol(-1)) film reached an electrical conductivity of (103.8 +/- 1.2) S cm, which is more than 20 times higher than the electrical conductivity of P3HT-M-10k (MW approximate to 10 000 g mol(-1)) and almost 30 % higher than the electrical conductivity of P3HT-M-100k (MW approximate to 100 000 g mol(-1)). Consequently, the maximum TE power factor of P3HT-M-50k at room temperature was as high as (22.6 +/- 0.6) mu W mK(-2), which is much higher than that of either P3HT-M-10k or P3HT-M-100k. Microstructure analysis combined with C-AFM suggested that carrier transport between most of the ordered and amorphous regions was unconnected in films with low molecular weights, and this resulted in a high migration barrier and poor carrier mobility. Upon increasing the molecular weight, the long molecular chain provided enough connectivity for the charge to move through the ordered regions, which decreased the carrier barrier and increased carrier mobility. Therefore, both the conductivity and Seebeck coefficient were significantly improved. However, a too-high molecular weight could cause more folding of the polymer chain, which would deteriorate the electrical-transport properties. The experimental results not only reveal the intrinsic effect of molecular weight on the electric transporting properties of conducting polymers but also suggest that molecular-weight engineering is an effective way to design and screen high-performance polymer TE materials.",
        "keywords": [
            "electrical transport",
            "molecular weight",
            "organic thermoelectrics",
            "polymers",
            "thin films"
        ],
        "authors": [
            {
                "name": "Sanyin Qu",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Qin Yao",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Bingxue Yu",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Kaiyang Zeng",
                "org": "Natl Univ Singapore, Dept Mech Engn, Singapore 117576, Singapore"
            },
            {
                "name": "Wei Shi",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Yanling Chen",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            },
            {
                "name": "Lidong Chen",
                "org": "Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China"
            }
        ],
        "venue": "CHEMISTRY-AN ASIAN JOURNAL",
        "year": 2018
    },
    "fbcnyenA": {
        "id": "fbcnyenA",
        "title": "Exploration and Practice on the Bilingual Education in Mechanical Courses for Provincial Level University",
        "abstract": "Bilingual teaching practices of structural mechanics are performed in some civil engineering classes in order to pursue the effective bilingual education methods for provincial level university.Some important factors that effect the bilingual education such as the characteristics of mechanical courses,the textbook,the bilingual ratio,the demand for teachers,and the teaching methods are discussed and analyzed.Bilingual education aims to enhance the students learning of professional knowledge,to equip students with the ability of using bilinguals not just the mother tongue to learn professional knowledge,and to meet the requirements that higher education should cultivate internationally competitive complex talent.",
        "keywords": [
            "Educational reform",
            "Provincial level university",
            "Mechanical courses",
            "Bilingual education"
        ],
        "authors": [
            {
                "name": "HOU Jing-peng",
                "org": "Architecture Engineering College,Northeast Dianli University,Jilin Jilin "
            },
            {
                "name": "SHI Wei",
                "org": "Architecture Engineering College,Northeast Dianli University,Jilin Jilin "
            },
            {
                "name": "JU Yan-zhong",
                "org": "Architecture Engineering College,Northeast Dianli University,Jilin Jilin "
            },
            {
                "name": "MA Li",
                "org": "Architecture Engineering College,Northeast Dianli University,Jilin Jilin "
            }
        ],
        "venue": "Journal of Northeast Dianli University",
        "year": 2011
    },
    "IgeeM6ss": {
        "id": "IgeeM6ss",
        "title": "The Annual Runoff Variation Trends in the Three Headstreams of Tarim River",
        "abstract": "Based on the observed annual runoff data of 5 hydrological stations in Tarim River headstreams areas from 1957 to 2008,the paper studied the annual trend,abrupt change,periodicity and the coming period trends by use of the nonparametric test,R/S analysis and wavelet analysis and so on.The results showed that:(1) Both Aksu river and Yarkand river of which the jump points happened at 1993 hold significant step change,but Hetian river expressed a slightly decreasing step trend and is not significant;(2)Aksu river holds a significant increasing trend but Yarkand river the trend is not,and based on the Hurst exponents(Aksu:0.777>0.5,Yarkand:0.485 7<0.5) of two the streams,the annual runoff of Aksu river will keep an increasing trend and Yarkand river will be in reverse in the coming period;Hetian river has a slightly decreasing trend and the Hurst exponent is 0.501 4,which equals 0.5 approximately and indicates that the annual runoff process is in chaos,then it can not be taken a long-term predict.(3) The primary periods of Aksu river and Hetian river are 6a,18a,22a and 9a,17a respectively,otherwise,Yarkant river is at 3a,9a,13a and 17a.",
        "keywords": [
            "runoff trends",
            "headstreams",
            "abrupt change",
            "nonparametric test"
        ],
        "authors": [
            {
                "name": "LING Hong-bo",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi,Xinjiang ,China;Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi,Xinjiang ,China"
            },
            {
                "name": "ZHANG Qing-qing",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi,Xinjiang ,China;Chinese Academy of Sciences,Beijing ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography,Chinese Academy of Sciences,Urumqi,Xinjiang ,China;Chinese Academy of Sciences,Beijing ,China"
            }
        ],
        "venue": "Scientia Geographica Sinica",
        "year": 2011
    },
    "f51RAn6O": {
        "id": "f51RAn6O",
        "title": "The Fractal and Fractal Dimensions of Manas River Valley Soil Spatial Distribution Based on RS/GIS",
        "abstract": "The fractal theory has advantages in describing the irregular geometry. Based on this theory, this paper researched the soil spatial fractal of Manas River Valley. The circumference- area quantitative relationship of different types of soil patches was established, and their fractal dimensions and stability indices were calculated. Some results were that there was a significant double logarithmic relationship between the circumference and area of soil patches, which indicated the existence of the soil spatial fractal in Manas River Valley. The fractal dimensions in different types of soil patches were different, declining gradually from south to north. The dimension of meadow saline soil, 1.7091, was the largest, and that of irrigated farming meadow calcareous soil, 1.0524, the smallest. While the stability index of irrigation farming meadow calcareous soil was the highest as 0.4476, and that of gray desert soil the lowest as 0.0223. The above parameters described quantitatively the soil characters in the Manas River Valley and provided reference for studies on the inner complexity of soil systems.",
        "keywords": [
            "Soil",
            "Fractal dimension",
            "Spatial distribution",
            "Manas River Valley",
            "Fractal"
        ],
        "authors": [
            {
                "name": "YU Pu-jia",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            },
            {
                "name": "XU Hai-liang",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            },
            {
                "name": "QIAO Mu",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            },
            {
                "name": "SHI Wei",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            },
            {
                "name": "LIU Shi-wei",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            },
            {
                "name": "AN Hong-yan",
                "org": "Xinjiang Institute of Ecology and Geography, Chinese Academy of Science, Urumqi, , China"
            }
        ],
        "venue": "Chinese Journal of Soil Science",
        "year": 2010
    },
    "eRArSsid": {
        "id": "eRArSsid",
        "title": "Application-oriented Context Modeling and Reasoning in Pervasive Computing",
        "abstract": "Context-awareness is considered as a key problem in designing more adaptive applications in pervasive computing community. Context modeling and reasoning, which deal with high-level abstraction and inference of pervasive contextual information, are important research areas of context-awareness computing. Efforts have been put into these two areas and several prototype systems have been proposed. However, the huge amounts of contextual information in pervasive environment make existing systems inefficient, even useless. In this paper, we propose enhanced application-oriented context modeling and reasoning (EACMR) system to deal with this problem. In EACMR system, we develop a context ontology (ACMRONT) to model the contexts in the pervasive computing. Different from previous researches, a context filter is designed to classify contexts by their importance. To promote the performance of the system, the reasoner in EACMR only deals with the application-related contextual information rather than all the available contextual information. Experiments about EACMR system demonstrate its higher performance than those of previous systems",
        "keywords": [
            "pervasive environment",
            "pervasive contextual information",
            "inference mechanisms",
            "context reasoning",
            "prototype system",
            "pervasive computing",
            "contextual information",
            "pervasive computing community",
            "context ontology",
            "previous system",
            "available contextual information",
            "ubiquitous computing",
            "context filter",
            "application-oriented context modeling",
            "ontologies (artificial intelligence)",
            "eacmr system",
            "context-awareness",
            "applicationrelated contextual information",
            "context model"
        ],
        "authors": [
            {
                "name": "Xin Lin",
                "org": "Zhejiang University"
            },
            {
                "name": "Shanping Li",
                "org": "Zhejiang University"
            },
            {
                "name": "Zhaohui Yang",
                "org": "Zhejiang University"
            },
            {
                "name": "Wei Shi",
                "org": "Zhejiang University"
            }
        ],
        "venue": "CIT",
        "year": 2005
    },
    "nZxTgkpX": {
        "id": "nZxTgkpX",
        "title": "Protein Chromatography Separation",
        "abstract": "Based on protein purification process often use of three kinds of methods,namely gel chromatography,ion exchange chromatography filterChromatography and affinity chromatography this three kinds of chromatography method,the principle of the major media and operating procedures are reviewed.",
        "keywords": [
            "Affinity chromatography",
            "Ion exchange chromatography",
            "Gel filtering chromatography"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Chengdu Vocational College of Agricultural Science and Technology,Chengdu ,China"
            }
        ],
        "venue": "Inner Mongolia Agricultural Science and Technology",
        "year": 2011
    },
    "2O6SqD3g": {
        "id": "2O6SqD3g",
        "title": "Effect of Guizhi Fuling Capsule on the Inflammatory Cytokines in Uterine Tissue of the Female Rats with Experimental Pelvic Inflammatory Disease",
        "abstract": "OBJECTIVE To investigate the effect of promoting blood circulation therapy on the expression of tumor necrosis factor-α(TNF-α) of inflammatory cytokines,transforming growth factor-β1(TGF-β1) of adhesion repairing-related indicators,vascular endothelial growth factor(VEGF),intercellular adhesion molecule-1(ICAM-1),and matrix metalloproteinase-2(MMP-2) in the uterine tissue of the female rats with pelvic inflammatory disease(PID).METHODS Mixed bacteria plus mechanical damage was used to establish animal model of PID.60 female rats were divided into five groups randomly and averagely:model group(PID group),three experimental groups with high,medium and low dose of Guizhi Fuling Capsule respectively,and positive control group(treated with Shaofu Zhuyu Capsule).In addition,sham operation group and normal control group were also set up with 12 rats in each group.The expression of TNF-α,TGF-β1 and VEGF were measured by immunohistochemical S-P method.RESULTS All index of model group were significantly higher than those of normal group and sham operation group(P<0.01,P<0.05).The expression of TNF-α,TGF-β1 and VEGF in experimental group and positive control group were a little higher than those of normal group and sham operation group without a significant difference(P>0.05).CONCLUSION The excessive inflammatory response exists in the uterine tissue of female rats with PID.The promoting blood circulation therapy may relieve or remove the local inflammation and decrease the incidence of PID sequela,by reducing the expression of TNF-α,TGF-β1,VEGF.",
        "keywords": [
            "promoting blood circulation therapy",
            "vascular endothelial growth factor",
            "uterine tissue of rats",
            "tumor necrosis factor-α",
            "transforming growth factor-β1",
            "pelvic inflammatory disease"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "The Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan,,China"
            },
            {
                "name": "LIU Rui-fen",
                "org": "The Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan,,China"
            },
            {
                "name": "YANG Xiao-na",
                "org": "Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing,,China"
            },
            {
                "name": "XU Li",
                "org": "Shandong Provincial Hospital,Ji'nan,,China"
            }
        ],
        "venue": "Journal of Nanjing University of Traditional Chinese Medicine",
        "year": 2012
    },
    "Fn1WJRYc": {
        "id": "Fn1WJRYc",
        "title": "Energy-efficient broadcasting algorithm in mobile ad hoc networks",
        "abstract": "Some nodes with many neighbors in the virtual backbone of broadcasting based on minimum connected dominating set (MCDS) are prone to being drained out quickly for more frequent packets relaying. A new relaying efficiency model was employed to reflect the trade off between network lifetime and global energy consumption according to the energy model of data transmission in mobile ad hoc networks and the battery-operated characteristic of mobile devices. The model considered the transmission power of different nodes and evaluated the lifetime of each node by its recent energy consumption based on the remained energy and the number of its neighbors. Then a multipoint-relaying based energy-efficient broadcasting algorithm (EE-MPR) was proposed. The algorithm constructed a broadcasting tree on the fly with smaller broadcasting cost by selecting fewer nodes with high relaying priority as relaying nodes. The energy load was evenly distributed among devices and the lifetime of network was prolonged. Simulation shows that EE-MPR outperforms the existing broadcasting algorithms in terms of the longest network lifetime and the minimum energy cost.",
        "keywords": [
            "Broadcasting algorithm",
            "Energy efficiency",
            "Mobile ad hoc networks",
            "Multipoint relaying"
        ],
        "authors": [
            {
                "name": "Wei Shi",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "LI Shan-ping",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "YANG Zhao-hui",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            },
            {
                "name": "Qing Gao",
                "org": "Zhejiang University(Zhejiang University),Hangzhou,China"
            }
        ],
        "venue": "Zhejiang Daxue Xuebao (Gongxue Ban)/Journal of Zhejiang University (Engineering Science)",
        "year": 2008
    },
    "2tVOmopc": {
        "id": "2tVOmopc",
        "title": "Long duplication of 18S ribosomal DNA in  (Pleuronectiformes: Cynoglossidae): novel molecular evidence for unequal crossing over model",
        "abstract": "Although 18S rDNA sequence is extremely conservative, the polymorphism still has been found in few species. In the present study, three types (Type A, B and C) of 18S rDNA sequence coexisted in Cynoglossus lineolatus genome, suggesting a non-concerted evolution process, rather than a strictly concerted evolution fashion. Based on the differences of sequence variation, GC content, secondary structure and minimum free energy, Types A and B were speculated as the potential pseudogenes. Additionally, a fascinating finding was a 189-bp duplication of 18S rDNA in Type A sequence. To our knowledge, this is the first report on such a long duplication in teleostean ribosomal DNA. Compared with several theories accounting for the formation of tandem repeats, the unequal crossing over model was thought to be the most likely mechanism to generate the 189-bp duplication of 18S rDNA. These results not only provide a novel molecular evidence for the unequal crossing over model, but also benefit for the further study on 18S rDNA in fishes.",
        "keywords": [
            "nrDNA",
            "Cynoglossus lineolatus",
            "tandem repeat",
            "pseudogene",
            "polymorphism",
            "non-concerted evolution"
        ],
        "authors": [
            {
                "name": "Li Gong",
                "org": "Guangxi Key Laboratory of Mangrove Conservation and Utilization, Guangxi Mangrove Research Center,Guangxi Academy of Sciences,Beihai,ChinaKey Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,ChinaUniversity of the Chinese Academy of Sciences,Beijing,China"
            },
            {
                "name": "Wei Shi",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,China"
            },
            {
                "name": "Min Yang",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,ChinaUniversity of the Chinese Academy of Sciences,Beijing,China"
            },
            {
                "name": "Lizhen Si",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,ChinaUniversity of the Chinese Academy of Sciences,Beijing,China"
            },
            {
                "name": "Xiaoyu Kong",
                "org": "Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,China"
            }
        ],
        "venue": "Acta Oceanologica Sinica",
        "year": 2016
    },
    "TZEWoHPq": {
        "id": "TZEWoHPq",
        "title": "Photoluminescence and Optical Absorption Properties of InGaN/GaN Single Quantum Well Grown by MOVPE",
        "abstract": "Gallium nitride and its ternary alloys have been attracting much attention because of their unique physical and chemical properties and their great potentialities for semiconductor industrial applications, such as light emitting diodes(LEDs), laser diodes(LDs) operating from green to ultraviolet(UV), UV-detectors and microwave power devices. The primary object of this study is to investigate the influence of different thickness of Fixed-Indium-Content InGaN layer on the shift of the photoluminescence(PL) spectra and optical absorption of the whole system structure. Photoluminescence(PL) and absorption properties of the Fixed-Indium-Content InGaN/GaN heterojunction single quantum well (SQW) structures have been investigated using photoluminescence spectrum and ultraviolet-vi-sible spectrophotometer at room temperature, respectively. The films were grown by metal-organic vapor phase epitaxy (MOVPE), using GaN buffer layer on sapphire substrates. The width of InGaN layer (<3 nm) in the SQW was varied while keeping other growth parameters fixed. Sample A has an InGaN active layer of thickness 1.5 nm, and Sample B has an InGaN active layer of thickness 2.5 nm. Two samples were capped with a 25 nm GaN layer. PL measurements show that the PL peak position (432 nm in Sample A and 465 nm in Sample B) was redshifted by 33 nm, the intensity was reduced about 8%, and the full width at half maximum (FWHM) of PL spectrum increases with increasing (1 nm) of the potential well layer width. The spectra of transmission and reflection show that transmission T is very high there can be only few reflection R as no absorption R+T exceeds 100% in the near infrared ranges for the sample with InGaN layer of thickness 1.5 nm. The reasons of these results are discussed. The significance of these studies is multifold and these results provide further information of importance toward the design optimization of optoelectronic devices employing the Ⅲ-nitrides.",
        "keywords": [
            "reflection spectra",
            "photoluminescence",
            "transmission spectra",
            "single quantum well",
            "InGaN/GaN"
        ],
        "authors": [
            {
                "name": "WANG Yue",
                "org": " Department of Applied Physics, Xi'an University of Technology, Xi'an , China"
            },
            {
                "name": "SHI Wei",
                "org": " Department of Applied Physics, Xi'an University of Technology, Xi'an , China"
            },
            {
                "name": "YUAN Jin-she",
                "org": " Department of Applied Physics, Xi'an University of Technology, Xi'an , China"
            },
            {
                "name": "HE Xun-jun",
                "org": " Department of Electronic Science and Technology, Harbin University of Science and Technology, Harbin , China"
            },
            {
                "name": "HU Hui",
                "org": " Department of Applied Physics, Xi'an University of Technology, Xi'an , China"
            },
            {
                "name": "JI Guang-ju",
                "org": " Department of Electronic Science and Technology, Harbin University of Science and Technology, Harbin , China"
            }
        ],
        "venue": "Chinese Journal of Luminescence",
        "year": 2007
    },
    "ei9WvBcO": {
        "id": "ei9WvBcO",
        "title": "Analysis of 643 cases with eminence lesions in the upper gastrointestinal tract by miniprobe endoscopic ultrasonography",
        "abstract": "Objective To evaluate the diagnostic value of the miniprobe endoscopic ultrasonography(mEUS) in the eminence lesions of upper gastrointestinal tract.Methods The 643 cases of upper gastrointestinal eminence lesions were examined by gastroscope within 626 patients then subsequently received mEUS,and the results were analyzed. Results With mEUS,339 lesions were located in the stomach,218 cases in the esophagus,69 cases in the duodenum and 17 cases in the cardia.Of 643 lesions,307 cases were diagnosed ultrasonographally as gastrointestinal stromal tumor(GIST),leiomyoma or leiomyosarcoma,62 etopic pancreas,25 adipoma,53 polypus,39 cyst and 9 angioma,respectively. Compression formed by extra-gastrointestinal lesions or adjacent normal organs were found in 89 cases.In 142 lesions,tissue samples were taken for pathological diagnosis.And 126 of them were consistent with mEUS findings.Conclusion mEUS is an ideal diagnostic modality in distinguishing different layers of the wall of the gastrointestinal tract,and thus of important value in precise localization of lesions beneath the mucosa. Although definite diagnosis still depends on pathology.It is now possible to accurately predict the histological nature in most cases based on such evidence obtained from mEUS as the location and imaging features of the lesion.However,difficulties apparently exist in differentiation of the GIST from the leiomyoma or leiomyosarcoma,and also between malignant and benign in myogenic tumors.",
        "keywords": [
            "Diagnosis",
            "Upper gastrointestinal tract",
            "Eminence lesions",
            "Miniprobe endoscopic ultrasonography"
        ],
        "authors": [
            {
                "name": "SHI Wei",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "SUN Xiaobin",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "ZHAO Cong",
                "org": "The Second People's Hospital of Chengdu,China"
            },
            {
                "name": "XI Weidong",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "YUAN Deqiang",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            },
            {
                "name": "NONG Chunyan",
                "org": "Department of Gastroenterology,the Third People's Hospital of Chengdu,Chengdu "
            }
        ],
        "venue": "Chinese Journal of Gastroenterology and Hepatology",
        "year": 2008
    },
    "NEZU4Jds": {
        "id": "NEZU4Jds",
        "title": "Novel Approaches to THz Sources and Detectors at Room Temperature for Imaging",
        "abstract": "",
        "keywords": [],
        "authors": [
            {
                "name": "wei shi",
                "org": ""
            },
            {
                "name": "yujie j ding",
                "org": ""
            }
        ],
        "venue": "",
        "year": 2005
    },
    "32V5XZRW": {
        "id": "32V5XZRW",
        "title": "Design of Power Management System Based on ZigBee and GPRS Network",
        "abstract": "In order to realize the automated management of the electricity sector,to improve their technical and management level,the authors proposed a data communication system combining ZigBee communication network and the GPRS network together.The program used CC2430 RF chip in the system,and the hardware and software design of data acquisition equipment,data concentrator equipment and ZigBee node were provided.The system is of the characteristics of low cost,fast response and easy maintenence,consistent with the concept of real-time and efficient management of electrical energy.",
        "keywords": [
            "GPRS network",
            "ZigBee communication network",
            "power management system"
        ],
        "authors": [
            {
                "name": "LU Juan",
                "org": "Taiyuan University of Technology,Taiyuan ,China"
            },
            {
                "name": "SHI Wei",
                "org": "Taiyuan University of Technology,Taiyuan ,China"
            }
        ],
        "venue": "Mechanical Engineering & Automation",
        "year": 2012
    },
    "EpYiUB4M": {
        "id": "EpYiUB4M",
        "title": "Structures and stability of small Ga_mAs_n clusters",
        "abstract": "Geometric structures and stability of GamAsn(m=1,2;n=1～5) clusters have been studied using the density functional theory(DFT).Structural optimization and frequency analysis were carried out at the B3LYP/6-31G* level.All ground state structures and meta-stable state structures of GamAsn(m=1,2;n=1～5) clusters have been obtained.Our calculations reveal the stability of GamAsn(m=1,2;n=1～5) clusters tends to increase with the increase of the number of total atoms.As-rich clusters are more stable than Ga-rich clusters generally among clusters with the same total atoms.The energy gap Egap between the highest-occupied molecular orbital(HOMO) and the lowest-unoccupied molecular orbital(LUMO),which depend on composition of the clusters and show an even/odd alteration